Comment diagnostiquer une activation des JNK ?

Des tests de signalisation cellulaire et des analyses protéomiques peuvent être utilisés.

Quels biomarqueurs indiquent l'activation des JNK ?

Des niveaux élevés de protéines phosphorylées c-Jun peuvent indiquer une activation.

Les tests génétiques sont-ils utiles pour les JNK ?

Oui, des tests peuvent identifier des mutations affectant la voie JNK.

Quels examens d'imagerie sont utilisés pour les JNK ?

L'imagerie par résonance magnétique peut aider à visualiser des effets cellulaires.

Peut-on mesurer l'activité des JNK dans le sang ?

Des échantillons sanguins peuvent être analysés pour des marqueurs d'activation.

Quels symptômes sont liés à l'activation des JNK ?

L'activation peut entraîner inflammation, apoptose et dysfonction cellulaire.

Les JNK sont-ils impliqués dans des maladies ?

Oui, ils sont associés à des maladies comme le cancer et les maladies neurodégénératives.

Comment les JNK affectent-ils la douleur ?

Ils modulent la signalisation de la douleur, contribuant à des douleurs chroniques.

Les JNK influencent-ils le métabolisme ?

Oui, ils jouent un rôle dans la régulation du métabolisme énergétique.

Y a-t-il des symptômes neurologiques associés aux JNK ?

Des troubles cognitifs et des troubles de l'humeur peuvent être observés.

Comment prévenir l'activation des JNK ?

Un mode de vie sain, incluant une alimentation équilibrée et de l'exercice, peut aider.

Le stress influence-t-il les JNK ?

Oui, le stress oxydatif peut activer les JNK, donc la gestion du stress est cruciale.

Les antioxydants aident-ils à prévenir l'activation des JNK ?

Oui, les antioxydants peuvent réduire le stress oxydatif et l'activation des JNK.

L'exercice physique prévient-il l'activation des JNK ?

Oui, l'exercice régulier peut moduler positivement l'activité des JNK.

Les habitudes alimentaires influencent-elles les JNK ?

Une alimentation riche en nutriments peut réduire l'activation des JNK.

Quels traitements ciblent les JNK ?

Des inhibiteurs spécifiques des JNK sont en développement pour diverses maladies.

Les anti-inflammatoires affectent-ils les JNK ?

Oui, certains anti-inflammatoires peuvent moduler l'activité des JNK.

La thérapie génique peut-elle cibler les JNK ?

La thérapie génique est explorée pour corriger des dysfonctionnements des JNK.

Les traitements naturels influencent-ils les JNK ?

Certaines plantes médicinales peuvent avoir un effet sur l'activation des JNK.

Les traitements anticancéreux ciblent-ils les JNK ?

Oui, des traitements anticancéreux visent à inhiber les voies JNK dans les cellules tumorales.

Quelles complications sont liées à l'activation des JNK ?

L'activation excessive des JNK peut entraîner des maladies inflammatoires et cancéreuses.

Les JNK sont-ils liés à des complications cardiovasculaires ?

Oui, l'activation des JNK est associée à des maladies cardiovasculaires.

Les JNK influencent-ils le vieillissement cellulaire ?

Oui, une activation prolongée des JNK peut accélérer le vieillissement cellulaire.

Y a-t-il des complications neurologiques liées aux JNK ?

Oui, l'activation des JNK est impliquée dans des troubles neurodégénératifs.

Les JNK sont-ils impliqués dans des complications métaboliques ?

Oui, ils sont liés à des troubles métaboliques comme le diabète.

Quels facteurs de risque influencent les JNK ?

Le stress, l'inflammation chronique et l'obésité sont des facteurs de risque connus.

L'alimentation affecte-t-elle les JNK ?

Oui, une alimentation riche en graisses saturées peut augmenter l'activation des JNK.

Le tabagisme influence-t-il les JNK ?

Oui, le tabagisme est un facteur de risque qui peut activer les JNK.

L'exposition à des toxines affecte-t-elle les JNK ?

Oui, l'exposition à des toxines environnementales peut activer les JNK.

Le manque d'exercice est-il un facteur de risque pour les JNK ?

Oui, un mode de vie sédentaire peut augmenter le risque d'activation des JNK.

JNK Mitogen-Activated Protein Kinases - Informations médicales vérifiées

A hypnotic turbo-induction technique for wisdom tooth extraction.

Apr 2023

DOI: 10.1080/00029157.2022.2123774 PMID: 36201742

The hypnotic turbo-induction technique has been used for more than three decades for various indications in dentistry and medicine. The use of the technique is described step by step using therapeutic...

Male Adult Humans Middle Aged Hypnosis +4 autres

Factors influencing opioid prescribing after tooth extraction.

09 2022

DOI: 10.1016/j.adaj.2022.05.001 PMID: 35691709

Tooth extractions account for most opioid prescriptions from dentists, but specific characteristics that influence likelihood are less established. Improving understanding can facilitate development o... The authors performed a retrospective review of patients 12 years and older undergoing tooth extraction at the College of Dentistry at the University of Kentucky from 2013 through 2020. The primary en... In 44,387 eligible records analyzed, 10,628 (23.9%) patients received an opioid prescription. Results of multivariable logistic regression found that the factors associated with an opioid prescription... Opioid prescriptions after tooth extraction were common in patients undergoing more extensive procedures. Provider perceptions, habits, and several clinical factors appeared to influence prescribing p... The decision to prescribe an opioid appears to be associated with habits and factors perceived to modulate postoperative pain, which may serve as targets for opioid reduction strategies....

Analgesics, Opioid Humans Pain, Postoperative Practice Patterns, Dentists' Practice Patterns, Physicians' +2 autres

Radiographic predictors for MRONJ in oncologic patients undergoing tooth extraction.

04 07 2022

DOI: 10.1038/s41598-022-15254-y PMID: 35789184

Tooth extraction is a risk factor for the development of osteonecrosis of the jaw following treatment with antiresorptive drugs (ARDs), but not all extraction sites develop this pathology. Therefore, ...

Bisphosphonate-Associated Osteonecrosis of the Jaw Bone Density Conservation Agents Humans Longitudinal Studies Respiratory Distress Syndrome +2 autres

3D bio-printing of photocrosslinked anatomically tooth-shaped scaffolds for alveolar ridge preservation after tooth extraction.

26 10 2022

DOI: 10.1039/d2tb01229d PMID: 36218074

Alveolar ridge preservation techniques have been developed as a possible method to maintain the optimum ridge contour and dimensions. Grafting a bone substitute is paramount to prevent alveolar ridge ...

Humans Alveolar Ridge Augmentation Bone Substitutes Polyurethanes Nacre +5 autres

Effects of dental anxiety and anesthesia on vital signs during tooth extraction.

29 May 2024

DOI: 10.1186/s12903-024-04404-5 PMID: 38811912

Anxiety is common preceding tooth extraction; hence, it is crucial to identify patients with dental anxiety (DA) and to manage DA. This study assessed the level of DA and influencing factors in tooth ... The study was a cohort study. The Dental Anxiety Scale (DAS) was used to assess the level of DA of 120 patients before tooth extraction. A Demographics and Oral Health Self-Assessment Form was used to... Based on the DAS score, 12.5% of the participants were identified as suffering from DA. DA was related to age, gender, and the self-assessment of oral health. The DAS score was correlated with increas... The prevalence of DA in adults was 12.5% in this study population. DA was related to gender, age, and the self-assessment of oral health. The score of DAS was correlated with BP. Compare to local anes...

Humans Dental Anxiety Tooth Extraction Female Male +13 autres

Tooth extraction prior to radiotherapy for oropharyngeal cancer increases the risk of osteoradionecrosis.

30 Mar 2023

DOI: 10.2334/josnusd.22-0392 PMID: 36858604

Osteoradionecrosis of the jaw is a therapy-resistant condition that may occur after treatment for head and neck cancer. The aim of this study was to investigate the incidence of osteoradionecrosis in ... Patients who had undergone radiation therapy for oropharyngeal cancer 5-10 years earlier were included and evaluated for the development of osteoradionecrosis (n = 75).... Among the 75 patients, 62 had molar teeth present in the >50 Gy radiation field and 36 of those patients had teeth extracted prior to radiation therapy. Extraction of molars before radiotherapy signif... Tooth extraction prior to radiation therapy increases the risk of developing osteoradionecrosis. For patients with good oral hygiene and absence of dental disease, avoidance of tooth extraction in the...

Tooth Extraction Oropharyngeal Neoplasms Osteoradionecrosis Jaw Diseases Head and Neck Neoplasms

Research on a novel digital tooth sectioning guide system for tooth sectioning during mandibular third molar extraction: An in vitro study.

02 2023

DOI: 10.1016/j.jormas.2023.101383 PMID: 36646285

To construct a novel portable tooth sectioning guide to improve the accuracy of mandibular third molar extraction.... First, 72 samples of an identical 3D-printed double-rooted mandibular third molar were obtained and used in 36 mandibular models. Three different models were constructed (class B vertical, mesial, and... Overall, the mean apical deviation of experienced/inexperienced operators using the conventional section technique was 1.120 mm (0.7 mm, 2.3 mm) and 1.54± 0.84 mm, respectively. Correspondingly, the m... In the digital guide technique, sectioning is more predictable and accurate, and the success of the operation is achievable with different proficiencies among dental surgeons.... This technique will not only reduce the difficulty of tooth extraction but also reduce the risk of damage to the surrounding soft and hard tissues, especially damage to the inferior alveolar nerve....

Humans Molar, Third Molar Tooth, Impacted Mandible +1 autres

Level of difficulty of tooth extractions among roughly 100,000 procedures in primary care.

Aug 2023

DOI: 10.1007/s00784-023-05073-4 PMID: 37231272

The study examined treatment codes of extracted teeth and aimed to assess degree of difficulty concerning all tooth extractions.... Retrospective data on treatment codes of all tooth extractions during a two-year period were obtained from the patient register in primary oral healthcare of the City of Helsinki, Finland. Prevalence,... Total number of extraction procedures was 97,276, including 121,342 extracted teeth. The most frequent procedure was a routine extraction of a tooth with forceps (55%, n = 53,642). The main reason for... Two-thirds of all tooth extractions in primary care were relatively simple. However, 29% of procedures were classified as demanding.... As earlier methods for assessing level of difficulty were aimed at third molars alone, an analysis was presented for all tooth extractions. This approach may be useful for research purposes, and the p...

Humans Retrospective Studies Tooth Extraction Dental Caries Molar, Third +1 autres

Quantification and visualization of the tooth extraction effects on face with spatially dense geometric morphometrics.

May 2023

DOI: 10.1111/ocr.12597 PMID: 35751510

To apply geometric morphometrics and multivariate statistics to evaluate changes of the face for female Chinese patients who underwent orthodontic treatment with different type of anchorage control.... Forty-six adult female patients were enrolled including 33 four first premolar extraction cases (17 patients with mini-implants for maximum anchorage control and 16 patients without mini-implants) and... The upper and lower lips were retruded significantly after treatment in the extraction groups. In the maximum anchorage control group, the temple and cheek were depressed by approximately 1 mm, and th... The anchorage choice and the removal of four first premolar extraction influence lip shape as well as the perioral regions. However, extraction treatment does not impact the appearance of the cheeks a...

Humans Female Cephalometry Tooth Extraction Lip

Antibiotic prescription after tooth extraction in adults: a retrospective cohort study in Austria.

20 11 2022

DOI: 10.1186/s12903-022-02556-w PMID: 36404324

Broad spectrum antibiotics are often used for the prophylaxis of infectious endocarditis and treatment of odontogenic infections, but there are limited data related to antibiotic use and adherence to ... From 43,863 patients with tooth extraction, 53% were female, and 3,983 patients (9.1%) filled a prescription for antibiotic medicine. From 43,863 patients, 157 patients (0.4%) had endocarditis risk, b... In this retrospective cohort study, dentists did not discriminate prophylactic antibiotic prescription with regard to endocarditis risk status. A factor influencing prescribing behaviour of antibiotic...

Humans Adult Female Male Anti-Bacterial Agents +5 autres

JNK Mitogen-Activated Protein Kinases : Questions médicales fréquentes

Termes MeSH sélectionnés :

Questions fréquentes et termes MeSH associés

Diagnostic 5

Symptômes 5

Prévention 5

Traitements 5

Complications 5

Facteurs de risque 5

Contenu validé par Dr Olivier Menir

Sous-catégories

Mitogen-Activated Protein Kinase 8

Mitogen-Activated Protein Kinase 9

Mitogen-Activated Protein Kinase 10

Auteurs principaux

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