Biodegradation of deoxynivalenol and its derivatives by Devosia insulae A16.
3-keto-DON
Biodegradation
DON derivatives
Deoxynivalenol
Devosia insulae
Journal
Food chemistry
ISSN: 1873-7072
Titre abrégé: Food Chem
Pays: England
ID NLM: 7702639
Informations de publication
Date de publication:
15 Mar 2019
15 Mar 2019
Historique:
received:
24
04
2018
revised:
15
09
2018
accepted:
02
10
2018
entrez:
10
11
2018
pubmed:
10
11
2018
medline:
3
1
2019
Statut:
ppublish
Résumé
Deoxynivalenol (DON), a notorious mycotoxin mainly found in Fusarium-contaminated crops, causes great loss in livestock farming and severe safety risks to human health. Here we report the isolation of a Gram-negative bacterial strain with effective biodegrading abilities on DON and its derivatives including 3-acetyl-DON and 15-acetyl-DON. The strain was identified as Devosia insulae A16 on the basis of morphological and physiological characteristics and 16S rRNA-based phylogenetic analysis. D. insulae A16 was able to degrade 88% of 20 mg/l DON within 48 h under aerobic conditions at 35 °C and neutral pH. The major degradation product of DON and its derivatives was 3-keto-DON by the oxidation of the hydroxyl group at C-3. Both 3-acetyl-DON and 15-acetyl-DON underwent a deacetylation reaction to generate DON prior to the degradation to 3-keto-DON. The results provide the potential use of D. insulae A16 as a biodegradation agent to control DON contamination in cereals.
Identifiants
pubmed: 30409617
pii: S0308-8146(18)31776-X
doi: 10.1016/j.foodchem.2018.10.011
pii:
doi:
Substances chimiques
RNA, Ribosomal, 16S
0
Trichothecenes
0
3-acetyldeoxynivalenol
50722-38-8
15-acetyldeoxynivalenol
88337-96-6
deoxynivalenol
JT37HYP23V
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
436-442Informations de copyright
Copyright © 2018 Elsevier Ltd. All rights reserved.