COVID-19 in lung transplant recipients.

Adenosine Monophosphate / analogs & derivatives Adult Aged Alanine / analogs & derivatives Antibodies, Monoclonal, Humanized / therapeutic use Antiviral Agents / therapeutic use COVID-19 / diagnostic imaging Cough / physiopathology Cross Infection / diagnostic imaging Cystic Fibrosis / surgery Dyspnea / physiopathology Female Fever / physiopathology Gastrointestinal Diseases / physiopathology Glucocorticoids / therapeutic use Graft Rejection / prevention & control Humans Idiopathic Pulmonary Fibrosis / surgery Immunoglobulins, Intravenous / therapeutic use Immunologic Factors / therapeutic use Immunosuppressive Agents / therapeutic use Interleukin 1 Receptor Antagonist Protein / therapeutic use Lung / diagnostic imaging Lung Transplantation Male Methylprednisolone / therapeutic use Middle Aged Pancreatitis, Acute Necrotizing Pulmonary Disease, Chronic Obstructive / surgery Pulse Therapy, Drug SARS-CoV-2 Sepsis Severity of Illness Index Tomography, X-Ray Computed
COVID-19 immune suppression lung transplant

Journal

Transplant infectious disease : an official journal of the Transplantation Society
ISSN: 1399-3062
Titre abrégé: Transpl Infect Dis
Pays: Denmark
ID NLM: 100883688

Informations de publication

Date de publication:
Dec 2020
Historique:
received: 26 05 2020
accepted: 27 05 2020
pubmed: 11 6 2020
medline: 12 1 2021
entrez: 11 6 2020
Statut: ppublish

Résumé

Solid organ transplant recipients are considered at high risk for COVID-19 infection due to chronic immune suppression; little data currently exists on the manifestations and outcomes of COVID-19 infection in lung transplant recipients. Here we report 8 cases of COVID-19 identified in patients with a history of lung transplant. We describe the clinical course of disease as well as preexisting characteristics of these patients.

Identifiants

DOI: 10.1111/tid.13364 PMID: 32521074 PMC: PMC7300568
pubmed: 32521074
doi: 10.1111/tid.13364
pmc: PMC7300568
doi:

Substances chimiques

Antibodies, Monoclonal, Humanized 0
Antiviral Agents 0
Glucocorticoids 0
Immunoglobulins, Intravenous 0
Immunologic Factors 0
Immunosuppressive Agents 0
Interleukin 1 Receptor Antagonist Protein 0
remdesivir 3QKI37EEHE
Adenosine Monophosphate 415SHH325A
tocilizumab I031V2H011
Alanine OF5P57N2ZX
Methylprednisolone X4W7ZR7023

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e13364

Informations de copyright

© 2020 Wiley Periodicals LLC.

Références

Ann Am Thorac Soc. 2020 Aug;17(8):922-925
pubmed: 32315201
N Engl J Med. 2020 Jun 18;382(25):2475-2477
pubmed: 32329975
J Heart Lung Transplant. 2020 Jun;39(6):610-611
pubmed: 32340870
Transpl Infect Dis. 2020 Dec;22(6):e13364
pubmed: 32521074
Am J Transplant. 2020 Jul;20(7):1800-1808
pubmed: 32330343

Auteurs

Catherine N Myers (CN)

Department of Thoracic Medicine and Surgery, Temple University Health Systems, Lewis Katz School of Medicine, Philadelphia, PA, USA.
ORCID: 0000-0002-3761-153X

John Harwood Scott (JH)

Department of Thoracic Medicine and Surgery, Temple University Health Systems, Lewis Katz School of Medicine, Philadelphia, PA, USA.

Gerard J Criner (GJ)

Department of Thoracic Medicine and Surgery, Temple University Health Systems, Lewis Katz School of Medicine, Philadelphia, PA, USA.

Francis C Cordova (FC)

Department of Thoracic Medicine and Surgery, Temple University Health Systems, Lewis Katz School of Medicine, Philadelphia, PA, USA.

Albert James Mamary (AJ)

Department of Thoracic Medicine and Surgery, Temple University Health Systems, Lewis Katz School of Medicine, Philadelphia, PA, USA.

Nathaniel Marchetti (N)

Department of Thoracic Medicine and Surgery, Temple University Health Systems, Lewis Katz School of Medicine, Philadelphia, PA, USA.

Kartik V Shenoy (KV)

Department of Thoracic Medicine and Surgery, Temple University Health Systems, Lewis Katz School of Medicine, Philadelphia, PA, USA.

Jonathan A Galli (JA)

Department of Thoracic Medicine and Surgery, Temple University Health Systems, Lewis Katz School of Medicine, Philadelphia, PA, USA.

Patrick D Mulhall (PD)

Department of Thoracic Medicine and Surgery, Temple University Health Systems, Lewis Katz School of Medicine, Philadelphia, PA, USA.

James C Brown (JC)

Department of Thoracic Medicine and Surgery, Temple University Health Systems, Lewis Katz School of Medicine, Philadelphia, PA, USA.

Norihisa Shigemura (N)

Department of Cardiovascular Surgery, Temple University Health Systems, Lewis Katz School of Medicine, Philadelphia, PA, USA.

Sameep Sehgal (S)

Department of Thoracic Medicine and Surgery, Temple University Health Systems, Lewis Katz School of Medicine, Philadelphia, PA, USA.

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Classifications MeSH

questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Nucléotides › Ribonucléotides › Nucléotides adényliques › AMP › COVID-19 in lung transplant recipients.
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › COVID-19 in lung transplant recipients.
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Sujet âgé › COVID-19 in lung transplant recipients.
questionsmedicales.fr › Acides aminés, peptides et protéines › Acides aminés › Alanine › COVID-19 in lung transplant recipients.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Globulines › Sérum-globulines › Immunoglobulines › Anticorps › Anticorps monoclonaux › Anticorps monoclonaux humanisés › COVID-19 in lung transplant recipients.
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antiviraux › COVID-19 in lung transplant recipients.
questionsmedicales.fr › Maladies de l'appareil respiratoire › Infections de l'appareil respiratoire › Pneumopathie infectieuse › Pneumopathie virale › COVID-19 › COVID-19 in lung transplant recipients.
questionsmedicales.fr › États, signes et symptômes pathologiques › Signes et symptômes › Signes et symptômes respiratoires › Toux › COVID-19 in lung transplant recipients.
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Caractéristiques de la maladie › Maladie iatrogène › Infection croisée › COVID-19 in lung transplant recipients.
questionsmedicales.fr › Malformations et maladies congénitales, héréditaires et néonatales › Maladies néonatales › Mucoviscidose › COVID-19 in lung transplant recipients.
questionsmedicales.fr › États, signes et symptômes pathologiques › Signes et symptômes › Signes et symptômes respiratoires › Dyspnée › COVID-19 in lung transplant recipients.
questionsmedicales.fr › États, signes et symptômes pathologiques › Signes et symptômes › Troubles de la température corporelle › Fièvre › COVID-19 in lung transplant recipients.
questionsmedicales.fr › Maladies de l'appareil digestif › Maladies gastro-intestinales › COVID-19 in lung transplant recipients.
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Hormones, substituts d'hormones et antagonistes d'hormones › Hormones › Glucocorticoïdes › COVID-19 in lung transplant recipients.
questionsmedicales.fr › Phénomènes du système immunitaire › Immunologie en transplantation › Réaction de l'hôte contre le greffon › Rejet du greffon › COVID-19 in lung transplant recipients.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › COVID-19 in lung transplant recipients.
questionsmedicales.fr › Maladies de l'appareil respiratoire › Maladies pulmonaires › Pneumopathies interstitielles › Fibrose pulmonaire idiopathique › COVID-19 in lung transplant recipients.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Globulines › Sérum-globulines › Immunoglobulines › Anticorps › Immunoglobulines par voie veineuse › COVID-19 in lung transplant recipients.
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Facteurs immunologiques › COVID-19 in lung transplant recipients.
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Facteurs immunologiques › Immunosuppresseurs › COVID-19 in lung transplant recipients.
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Antagoniste du récepteur à l'interleukine-1 › COVID-19 in lung transplant recipients.
questionsmedicales.fr › Appareil respiratoire › Poumon › COVID-19 in lung transplant recipients.
questionsmedicales.fr › Procédures de chirurgie opératoire › Transplantation › Transplantation d'organe › Transplantation pulmonaire › COVID-19 in lung transplant recipients.
questionsmedicales.fr › Composés polycycliques › Composés à cycles fusionnés › Stéroïdes › Prégnanes › Prégnadiènes › Prégnadiènetriols › Prednisolone › Méthylprednisolone › COVID-19 in lung transplant recipients.
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Adulte d'âge moyen › COVID-19 in lung transplant recipients.
questionsmedicales.fr › Maladies de l'appareil digestif › Maladies du pancréas › Pancréatite › Pancréatite aigüe nécrotique › COVID-19 in lung transplant recipients.
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Caractéristiques de la maladie › Maladie chronique › Broncho-pneumopathie chronique obstructive › COVID-19 in lung transplant recipients.
questionsmedicales.fr › Thérapeutique › Traitement médicamenteux › Calendrier d'administration des médicaments › Pharmacothérapie administrée en bolus › COVID-19 in lung transplant recipients.
questionsmedicales.fr › Virus › Virus à ARN › Virus à ARN à brin positif › Nidovirales › Coronaviridae › Coronavirus › Betacoronavirus › Virus du SRAS › SARS-CoV-2 › COVID-19 in lung transplant recipients.
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Inflammation › Sepsie › COVID-19 in lung transplant recipients.
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Collecte de données › Enquêtes et questionnaires › Enquêtes de santé › Indicateurs d'état de santé › Acuité des besoins du patient › Indice de gravité de la maladie › COVID-19 in lung transplant recipients.
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Imagerie diagnostique › Tomographie › Tomographie à rayons X › Tomodensitométrie › COVID-19 in lung transplant recipients.