Adult
Aged
Aged, 80 and over
Biomarkers, Tumor
/ antagonists & inhibitors
DNA Mutational Analysis
Drug Resistance, Neoplasm
/ genetics
Exons
/ genetics
Female
Humans
Lung
/ pathology
Lung Neoplasms
/ drug therapy
Male
Middle Aged
Progression-Free Survival
Prospective Studies
Protein Kinase Inhibitors
/ pharmacology
Proto-Oncogene Proteins c-met
/ antagonists & inhibitors
Journal
Clinical cancer research : an official journal of the American Association for Cancer Research
ISSN: 1557-3265
Titre abrégé: Clin Cancer Res
Pays: United States
ID NLM: 9502500
Informations de publication
Date de publication:
01 02 2021
01 02 2021
Historique:
received:
22
07
2020
revised:
17
09
2020
accepted:
04
11
2020
pubmed:
12
11
2020
medline:
19
1
2022
entrez:
11
11
2020
Statut:
ppublish
Résumé
MET tyrosine kinase inhibitors (TKIs) can achieve modest clinical outcomes in We performed hybrid capture-based DNA sequencing, targeted RNA sequencing, cell-free DNA sequencing, selected reaction monitoring mass spectrometry (SRM-MS), and immunohistochemistry on patient samples of Seventy-five of 168 In
Identifiants
pubmed: 33172896
pii: 1078-0432.CCR-20-2861
doi: 10.1158/1078-0432.CCR-20-2861
pmc: PMC7854494
mid: NIHMS1645730
doi:
Substances chimiques
Biomarkers, Tumor
0
Protein Kinase Inhibitors
0
MET protein, human
EC 2.7.10.1
Proto-Oncogene Proteins c-met
EC 2.7.10.1
Types de publication
Journal Article
Observational Study
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
799-806Subventions
Organisme : NCI NIH HHS
ID : R25 CA020449
Pays : United States
Organisme : NCI NIH HHS
ID : T32 CA009207
Pays : United States
Organisme : NCI NIH HHS
ID : P30 CA008748
Pays : United States
Organisme : NCATS NIH HHS
ID : KL2 TR002385
Pays : United States
Organisme : NCI NIH HHS
ID : P01 CA129243
Pays : United States
Organisme : NIDDK NIH HHS
ID : R21 DK061004
Pays : United States
Informations de copyright
©2020 American Association for Cancer Research.
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