Alexander Drilon

Affiliations

Memorial Sloan Kettering Cancer Center, New York, New York.
Weill Cornell Medical College, New York, New York.

Publications (95)

A Phase Ib/II Study of Ramucirumab in Combination with Emibetuzumab in Patients with Advanced Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: James J Harding , Andrew X Zhu , Todd M Bauer , Toni K Choueiri , Alexander Drilon , Martin H Voss , Charles S Fuchs , Ghassan K Abou-Alfa , Sameera R Wijayawardana , Xuejing Aimee Wang , Brian A Moser , Arantxa Uruñuela , Volker Wacheck , Johanna C Bendell

Five-Year Survival and Correlates Among Patients With Advanced Melanoma, Renal Cell Carcinoma, or Non-Small Cell Lung Cancer Treated With Nivolumab.

JAMA oncology

Avec: Suzanne L Topalian , F Stephen Hodi , Julie R Brahmer , Scott N Gettinger , David C Smith , David F McDermott , John D Powderly , Jeffrey A Sosman , Michael B Atkins , Philip D Leming , David R Spigel , Scott J Antonia , Alexander Drilon , Jedd D Wolchok , Richard D Carvajal , M Brent McHenry , Fareeda Hosein , Christopher T Harbison , Joseph F Grosso , Mario Sznol

Colorectal Carcinomas Containing Hypermethylated MLH1 Promoter and Wild-Type BRAF/KRAS Are Enriched for Targetable Kinase Fusions.

Cancer research

Avec: Emiliano Cocco , Jamal Benhamida , Sumit Middha , Ahmet Zehir , Kerry Mullaney , Jinru Shia , Rona Yaeger , Liying Zhang , Donna Wong , Liliana Villafania , Khedoudja Nafa , Maurizio Scaltriti , Alexander Drilon , Leonard Saltz , Alison M Schram , Zsofia K Stadler , David M Hyman , Ryma Benayed , Marc Ladanyi , Jaclyn F Hechtman

Optimizing the sequencing of tyrosine kinase inhibitors (TKIs) in epidermal growth factor receptor (EGFR) mutation-positive non-small cell lung cancer (NSCLC).

Lung cancer (Amsterdam, Netherlands)

Avec: Ana C Z Gelatti , Alexander Drilon , Fernando C Santini

Enrichment of kinase fusions in ESR1 wild-type, metastatic breast cancer revealed by a systematic analysis of 4854 patients.

Annals of oncology : official journal of the European Society for Medical Oncology

Avec: D S Ross , B Liu , A M Schram , P Razavi , S M Lagana , Y Zhang , M Scaltriti , J F Bromberg , M Ladanyi , D M Hyman , A Drilon , A Zehir , R Benayed , S Chandarlapaty , J F Hechtman

TRK inhibitors in TRK fusion-positive cancers.

Annals of oncology : official journal of the European Society for Medical Oncology

Avec: A Drilon

COVID-19 in patients with lung cancer.

Annals of oncology : official journal of the European Society for Medical Oncology

Avec: J Luo , H Rizvi , I R Preeshagul , J V Egger , D Hoyos , C Bandlamudi , C G McCarthy , C J Falcon , A J Schoenfeld , K C Arbour , J E Chaft , R M Daly , A Drilon , J Eng , A Iqbal , W V Lai , B T Li , P Lito , A Namakydoust , K Ng , M Offin , P K Paik , G J Riely , C M Rudin , H A Yu , M G Zauderer , M T A Donoghue , M Łuksza , B D Greenbaum , M G Kris , M D Hellmann

Larotrectinib in patients with TRK fusion-positive solid tumours: a pooled analysis of three phase 1/2 clinical trials.

The Lancet. Oncology

Avec: David S Hong , Steven G DuBois , Shivaani Kummar , Anna F Farago , Catherine M Albert , Kristoffer S Rohrberg , Cornelis M van Tilburg , Ramamoorthy Nagasubramanian , Jordan D Berlin , Noah Federman , Leo Mascarenhas , Birgit Geoerger , Afshin Dowlati , Alberto S Pappo , Stefan Bielack , François Doz , Ray McDermott , Jyoti D Patel , Russell J Schilder , Makoto Tahara , Stefan M Pfister , Olaf Witt , Marc Ladanyi , Erin R Rudzinski , Shivani Nanda , Barrett H Childs , Theodore W Laetsch , David M Hyman , Alexander Drilon

KRAS as a druggable target in NSCLC: Rising like a phoenix after decades of development failures.

Cancer treatment reviews

Avec: Alex Friedlaender , Alexander Drilon , Glen J Weiss , Giuseppe L Banna , Alfredo Addeo

RET inhibition in novel patient-derived models of RET-fusion positive lung adenocarcinoma reveals a role for MYC upregulation.

Disease models & mechanisms

Avec: Takuo Hayashi , Igor Odintsov , Roger S Smith , Kota Ishizawa , Allan J W Liu , Lukas Delasos , Christopher Kurzatkowski , Huichun Tai , Eric Gladstone , Morana Vojnic , Shinji Kohsaka , Ken Suzawa , Zebing Liu , Siddharth Kunte , Marissa S Mattar , Inna Khodos , Monika A Davare , Alexander Drilon , Emily Cheng , Elisa de Stanchina , Marc Ladanyi , Romel Somwar

A Performance Comparison of Commonly Used Assays to Detect RET Fusions.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Soo-Ryum Yang , Umut Aypar , Ezra Y Rosen , Douglas A Mata , Ryma Benayed , Kerry Mullaney , Gowtham Jayakumaran , Yanming Zhang , Denise Frosina , Alexander Drilon , Marc Ladanyi , Achim A Jungbluth , Natasha Rekhtman , Jaclyn F Hechtman

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Gregory D Jones , Raul Caso , Kay See Tan , Brooke Mastrogiacomo , Francisco Sanchez-Vega , Yuan Liu , James G Connolly , Yonina R Murciano-Goroff , Matthew J Bott , Prasad S Adusumilli , Daniela Molena , Gaetano Rocco , Valerie W Rusch , Smita Sihag , Sandra Misale , Rona Yaeger , Alexander Drilon , Kathryn C Arbour , Gregory J Riely , Neal Rosen , Piro Lito , Haiying Zhang , David C Lyden , Charles M Rudin , David R Jones , Bob T Li , James M Isbell

Efficacy and Safety of Larotrectinib in Patients With Tropomyosin Receptor Kinase Fusion-Positive Lung Cancers.

JCO precision oncology

Avec: Alexander Drilon , Daniel S W Tan , Ulrik N Lassen , Serge Leyvraz , Yongmei Liu , Jyoti D Patel , Lee Rosen , Benjamin Solomon , Ricarda Norenberg , Laura Dima , Nicoletta Brega , Lin Shen , Victor Moreno , Shivaani Kummar , Jessica J Lin

Correlation between treatment effects on response rate and progression-free survival and overall survival in trials of targeted therapies in molecularly enriched populations.

ESMO open

Avec: B J Solomon , H H Loong , Y Summers , Z M Thomas , P French , B K Lin , A Sashegyi , J Wolf , J C-H Yang , A Drilon

Larotrectinib Treatment for Patients With TRK Fusion-Positive Salivary Gland Cancers.

The oncologist

Avec: Xiuning Le , Christina Baik , Jessica Bauman , Jill Gilbert , Marcia S Brose , Juneko E Grilley-Olson , Tejas Patil , Ray McDermott , Luis E Raez , Jennifer M Johnson , Lin Shen , Makoto Tahara , Alan L Ho , Ricarda Norenberg , Laura Dima , Nicoletta Brega , Alexander Drilon , David S Hong

Immunogenicity and therapeutic targeting of a public neoantigen derived from mutated PIK3CA.

Nature medicine

Avec: Smita S Chandran , Jiaqi Ma , Martin G Klatt , Friederike Dündar , Chaitanya Bandlamudi , Pedram Razavi , Hannah Y Wen , Britta Weigelt , Paul Zumbo , Si Ning Fu , Lauren B Banks , Fei Yi , Enric Vercher , Inaki Etxeberria , Watchain D Bestman , Arnaud Da Cruz Paula , Ilinca S Aricescu , Alexander Drilon , Doron Betel , David A Scheinberg , Brian M Baker , Christopher A Klebanoff

Selpercatinib in Patients With

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Avec: Alexander Drilon , Vivek Subbiah , Oliver Gautschi , Pascale Tomasini , Filippo de Braud , Benjamin J Solomon , Daniel Shao-Weng Tan , Guzmán Alonso , Jürgen Wolf , Keunchil Park , Koichi Goto , Victoria Soldatenkova , Sylwia Szymczak , Scott S Barker , Tarun Puri , Aimee Bence Lin , Herbert Loong , Benjamin Besse

Outcomes With Local Therapy and Tyrosine Kinase Inhibition in Patients With

JCO precision oncology

Avec: Harper Hubbeling , Noura Choudhury , Jessica Flynn , Zhigang Zhang , Christina Falcon , Valerie W Rusch , Bernard J Park , Etay Ziv , Narek Shaverdian , Daphna Y Gelblum , Annemarie F Shepherd , Charles B Simone , Abraham J Wu , Daniel R Gomez , Alexander Drilon , Andreas Rimner

Central Nervous System Disease in Patients With RET Fusion-Positive NSCLC Treated With Selpercatinib.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

Avec: Yonina R Murciano-Goroff , Christina J Falcon , Sabrina T Lin , Christina Chacko , Grace Grimaldi , Dazhi Liu , Clare Wilhelm , Alexia Iasonos , Alexander Drilon

Case Report: Complete pathologic response to neoadjuvant selpercatinib in a patient with resectable early-stage

Frontiers in oncology

Avec: Jonathan W Goldman , Lynette M Sholl , Sanja Dacic , Michael C Fishbein , Yonina R Murciano-Goroff , Ravi Rajaram , Sylwia Szymczak , Anna M Szpurka , Bo H Chao , Alexander Drilon

Rationale and design of ON-TRK: a novel prospective non-interventional study in patients with TRK fusion cancer treated with larotrectinib.

BMC cancer

Avec: James C H Yang , Marcia S Brose , Gilberto Castro , Edward S Kim , Ulrik N Lassen , Serge Leyvraz , Alberto Pappo , Fernando López-Ríos , John A Reeves , Marc Fellous , Frédérique Penault-Llorca , Erin R Rudzinski , Ghazaleh Tabatabai , Gilles Vassal , Alexander Drilon , Jonathan Trent

Zurletrectinib is a next-generation TRK inhibitor with strong intracranial activity against NTRK fusion-positive tumours with on-target resistance to first-generation agents.

British journal of cancer

Avec: Paola Roa , Valentina Foglizzo , Guilherme Harada , Matteo Repetto , Amanda Kulick , Elisa de Stanchina , Michelle de Marchena , Supipi Auwardt , Shaza Sayed Ahmed , Nicole Virginia Bremer , Soo-Ryum Yang , Yangbo Feng , Chao Zhou , Norman Kong , Ruixia Liang , Haipeng Xu , Bin Zhang , Alberto Bardelli , Eneda Toska , Andrea Ventura , Alexander Drilon , Emiliano Cocco

Optimal systemic treatment and real-world clinical application of ctDNA in patients with metastatic HER2-mutant lung cancer.

European journal of cancer (Oxford, England : 1990)

Avec: Si-Yang Liu , Tatiana Erazo , Justin Jee , Andrea Arfe , Avantika Gupta , Luke R G Pike , Fernando C Santini , Bobby Daly , Adam Schoenfeld , Jordan Eichholz , Kaylie Johnson , Andres Martinez , Jane Sui , Nadeem Riaz , Jason Chang , Soo-Ryum Yang , William Travis , Maria E Arcila , Jiannan Guo , Eric Gagne , Kavita Garg , Frederick Baehner , Nancy Y Lee , Alexander Drilon , Mark G Kris , Howard I Scher , Pedram Razavi , Daniel R Gomez , David R Jones , Charles M Rudin , Sarat Chandarlapaty , James M Isbell , Bob T Li

RET Solvent Front Mutations Mediate Acquired Resistance to Selective RET Inhibition in RET-Driven Malignancies.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

Avec: Benjamin J Solomon , Lavinia Tan , Jessica J Lin , Stephen Q Wong , Sebastian Hollizeck , Kevin Ebata , Brian B Tuch , Satoshi Yoda , Justin F Gainor , Lecia V Sequist , Geoffrey R Oxnard , Oliver Gautschi , Alexander Drilon , Vivek Subbiah , Christine Khoo , Edward Y Zhu , Michele Nguyen , Dahlia Henry , Kevin R Condroski , Gabrielle R Kolakowski , Eliana Gomez , Joshua Ballard , Andrew T Metcalf , James F Blake , Sarah-Jane Dawson , Wayne Blosser , Louis F Stancato , Barbara J Brandhuber , Steve Andrews , Bruce G Robinson , S Michael Rothenberg

Characterization of on-target adverse events caused by TRK inhibitor therapy.

Annals of oncology : official journal of the European Society for Medical Oncology

Avec: D Liu , J Flory , A Lin , M Offin , C J Falcon , Y R Murciano-Goroff , E Rosen , R Guo , E Basu , B T Li , J J Harding , G Iyer , K Jhaveri , M M Gounder , N N Shukla , S S Roberts , J Glade-Bender , L Kaplanis , A Schram , D M Hyman , A Drilon

TRK Fusions Are Enriched in Cancers with Uncommon Histologies and the Absence of Canonical Driver Mutations.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Ezra Y Rosen , Debra A Goldman , Jaclyn F Hechtman , Ryma Benayed , Alison M Schram , Emiliano Cocco , Sophie Shifman , Yixiao Gong , Ritika Kundra , James P Solomon , Alberto Bardelli , Maurizio Scaltriti , Alexander Drilon , Alexia Iasonos , Barry S Taylor , David M Hyman

MET-dependent solid tumours - molecular diagnosis and targeted therapy.

Nature reviews. Clinical oncology

Avec: Robin Guo , Jia Luo , Jason Chang , Natasha Rekhtman , Maria Arcila , Alexander Drilon

Therapeutic Potential of Afatinib in NRG1 Fusion-Driven Solid Tumors: A Case Series.

The oncologist

Avec: Jacques Cadranel , Stephen V Liu , Michaël Duruisseaux , Eva Branden , Yasushi Goto , Benjamin A Weinberg , Christoph Heining , Richard F Schlenk , Parneet Cheema , Martin R Jones , Alexander Drilon , Domenico Trombetta , Lucia Anna Muscarella , Khaled Tolba , Valerie Gounant , Agnieszka Cseh , Flavio Solca , Janessa J Laskin , Daniel J Renouf

The METeoric rise of MET in lung cancer.

Cancer

Avec: Alex Friedlaender , Alexander Drilon , Giuseppe Luigi Banna , Solange Peters , Alfredo Addeo

Four-year survival with nivolumab in patients with previously treated advanced non-small-cell lung cancer: a pooled analysis.

The Lancet. Oncology

Avec: Scott J Antonia , Hossein Borghaei , Suresh S Ramalingam , Leora Horn , Javier De Castro Carpeño , Adam Pluzanski , Marco A Burgio , Marina Garassino , Laura Q M Chow , Scott Gettinger , Lucio Crinò , David Planchard , Charles Butts , Alexander Drilon , Joanna Wojcik-Tomaszewska , Gregory A Otterson , Shruti Agrawal , Ang Li , John R Penrod , Julie Brahmer

Tumor Mutation Burden and Efficacy of EGFR-Tyrosine Kinase Inhibitors in Patients with

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Michael Offin , Hira Rizvi , Megan Tenet , Andy Ni , Francisco Sanchez-Vega , Bob T Li , Alexander Drilon , Mark G Kris , Charles M Rudin , Nikolaus Schultz , Maria E Arcila , Marc Ladanyi , Gregory J Riely , Helena Yu , Matthew D Hellmann

Resistance to TRK inhibition mediated by convergent MAPK pathway activation.

Nature medicine

Avec: Emiliano Cocco , Alison M Schram , Amanda Kulick , Sandra Misale , Helen H Won , Rona Yaeger , Pedram Razavi , Ryan Ptashkin , Jaclyn F Hechtman , Eneda Toska , James Cownie , Romel Somwar , Sophie Shifman , Marissa Mattar , S Duygu Selçuklu , Aliaksandra Samoila , Sean Guzman , Brian B Tuch , Kevin Ebata , Elisa de Stanchina , Rebecca J Nagy , Richard B Lanman , Brian Houck-Loomis , Juber A Patel , Michael F Berger , Marc Ladanyi , David M Hyman , Alexander Drilon , Maurizio Scaltriti

Author Correction: HER kinase inhibition in patients with HER2- and HER3-mutant cancers.

Nature

Avec: David M Hyman , Sarina A Piha-Paul , Helen Won , Jordi Rodon , Cristina Saura , Geoffrey I Shapiro , Dejan Juric , David I Quinn , Victor Moreno , Bernard Doger , Ingrid A Mayer , Valentina Boni , Emiliano Calvo , Sherene Loi , Albert C Lockhart , Joseph P Erinjeri , Maurizio Scaltriti , Gary A Ulaner , Juber Patel , Jiabin Tang , Hannah Beer , S Duygu Selcuklu , Aphrothiti J Hanrahan , Nancy Bouvier , Myra Melcer , Rajmohan Murali , Alison M Schram , Lillian M Smyth , Komal Jhaveri , Bob T Li , Alexander Drilon , James J Harding , Gopa Iyer , Barry S Taylor , Michael F Berger , Richard E Cutler , Feng Xu , Anna Butturini , Lisa D Eli , Grace Mann , Cynthia Farrell , Alshad S Lalani , Richard P Bryce , Carlos L Arteaga , Funda Meric-Bernstam , José Baselga , David B Solit

CNS Metastases in Patients With

JCO precision oncology

Avec: Michael Offin , Jia Luo , Robin Guo , John K Lyo , Christina Falcon , Jordan Dienstag , Olivia Wilkins , Jason Chang , Charles M Rudin , Gregory Riely , Natasha Rekhtman , Maria E Arcila , Glenn Heller , Marc Ladanyi , Bob T Li , Mark G Kris , Paul Paik , Alexander Drilon

Real-World Outcomes of an Automated Physician Support System for Genome-Driven Oncology.

JCO precision oncology

Avec: Jessica J Tao , Michael H Eubank , Alison M Schram , Nicholas Cangemi , Erika Pamer , Ezra Y Rosen , Nikolaus Schultz , Debyani Chakravarty , John Philip , Jaclyn F Hechtman , James J Harding , Lillian M Smyth , Komal L Jhaveri , Alexander Drilon , Marc Ladanyi , David B Solit , Ahmet Zehir , Michael F Berger , Peter D Stetson , Stuart M Gardos , David M Hyman

Secretory Carcinoma of the Thyroid in a 49-Year-Old Man Treated with Larotrectinib: Protracted Clinical Course of Disease Despite the High-Grade Histologic Features.

Head and neck pathology

Avec: Maelle Saliba , Abhinita S Mohanty , Alan L Ho , Alexander Drilon , Snjezana Dogan

Phase 1 multicenter study of the HSP90 inhibitor SNX-5422 plus carboplatin and paclitaxel in patients with lung cancers.

Lung cancer (Amsterdam, Netherlands)

Avec: Martin Gutierrez , Robin Guo , Giuseppe Giaccone , Stephen V Liu , Zhonglin Hao , Christie Hilton , James M Hinson , Mark G Kris , Everardus Otto Orlemans , Alexander Drilon

The NCI-MATCH: A National, Collaborative Precision Oncology Trial for Diverse Tumor Histologies.

Cancer cell

Avec: Yonina R Murciano-Goroff , Alexander Drilon , Zsofia K Stadler

Comprehensive Molecular and Clinicopathologic Analysis of 200 Pulmonary Invasive Mucinous Adenocarcinomas Identifies Distinct Characteristics of Molecular Subtypes.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Jason C Chang , Michael Offin , Christina Falcon , David Brown , Brian R Houck-Loomis , Fanli Meng , Vasilisa A Rudneva , Helen H Won , Sharon Amir , Joseph Montecalvo , Patrice Desmeules , Kyuichi Kadota , Prasad S Adusumilli , Valerie W Rusch , Sarah Teed , Joshua K Sabari , Ryma Benayed , Khedoudja Nafa , Laetitia Borsu , Bob T Li , Alison M Schram , Maria E Arcila , William D Travis , Marc Ladanyi , Alexander Drilon , Natasha Rekhtman

Quality of Life in Adult and Pediatric Patients with Tropomyosin Receptor Kinase Fusion Cancer Receiving Larotrectinib.

Current problems in cancer

Avec: Shivaani Kummar , Jordan Berlin , Leo Mascarenhas , Cornelis M van Tilburg , Birgit Geoerger , Ulrik N Lassen , Russell J Schilder , Brian Turpin , Shivani Nanda , Karen Keating , Barrett H Childs , Costel Chirila , Theodore W Laetsch , David M Hyman , Alexander Drilon , David S Hong

Invasive Mucinous Adenocarcinomas With Spatially Separate Lung Lesions: Analysis of Clonal Relationship by Comparative Molecular Profiling.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

Avec: Soo-Ryum Yang , Jason C Chang , Charles Leduc , Kay See Tan , Snjezana Dogan , Ryma Benayed , Laetitia Borsu , Michael Offin , Alexander Drilon , William D Travis , Maria E Arcila , Marc Ladanyi , Natasha Rekhtman

Characterization and management of ERK inhibitor associated dermatologic adverse events: analysis from a nonrandomized trial of ulixertinib for advanced cancers.

Investigational new drugs

Avec: J Wu , D Liu , M Offin , C Lezcano , J M Torrisi , S Brownstein , D M Hyman , M M Gounder , W Abida , A Drilon , J J Harding , R J Sullivan , F Janku , D Welsch , M Varterasian , A Groover , B T Li , M E Lacouture

Clinical and Morphologic Characteristics of Fibroblast Growth Factor Receptor Inhibitor-Associated Retinopathy.

JAMA ophthalmology

Avec: Jasmine H Francis , James J Harding , Alison M Schram , Julia Canestraro , Dianna Haggag-Lindgren , Murk Heinemann , Anuja Kriplani , Komal Jhaveri , Martin H Voss , Dean Bajorin , Ghassan K Abou-Alfa , Gopa Iyer , Alexander Drilon , Jonathan Rosenberg , David H Abramson

TRK inhibitor activity and resistance in TRK fusion-positive cancers in adults.

Cancer genetics

Avec: Guilherme Harada , Alexander Drilon

Repotrectinib in

The New England journal of medicine

Avec: Alexander Drilon , D Ross Camidge , Jessica J Lin , Sang-We Kim , Benjamin J Solomon , Rafal Dziadziuszko , Benjamin Besse , Koichi Goto , Adrianus Johannes de Langen , Jürgen Wolf , Ki Hyeong Lee , Sanjay Popat , Christoph Springfeld , Misako Nagasaka , Enriqueta Felip , Nong Yang , Vamsidhar Velcheti , Shun Lu , Steven Kao , Christophe Dooms , Matthew G Krebs , Wenxiu Yao , Muhammad Shaalan Beg , Xiufeng Hu , Denis Moro-Sibilot , Parneet Cheema , Shanna Stopatschinskaja , Minal Mehta , Denise Trone , Armin Graber , Gregory Sims , Yong Yuan , Byoung Chul Cho , Auteur inconnu

Phase I study of lurbinectedin in combination with weekly paclitaxel with or without bevacizumab in patients with advanced solid tumors.

Investigational new drugs

Avec: Emiliano Calvo , Cristiana Sessa , Guilherme Harada , Maria de Miguel , Carmen Kahatt , Xarles Erik Luepke-Estefan , Mariano Siguero , Carlos Fernandez-Teruel , Martin Cullell-Young , Anastasios Stathis , Alexander Drilon

Tumour-agnostic efficacy and safety of selpercatinib in patients with RET fusion-positive solid tumours other than lung or thyroid tumours (LIBRETTO-001): a phase 1/2, open-label, basket trial.

The Lancet. Oncology

Avec: Vivek Subbiah , Jürgen Wolf , Bhavana Konda , Hyunseok Kang , Alexander Spira , Jared Weiss , Masayuki Takeda , Yuichiro Ohe , Saad Khan , Kadoaki Ohashi , Victoria Soldatenkova , Sylwia Szymczak , Loretta Sullivan , Jennifer Wright , Alexander Drilon

Precision Oncology: 2022 in Review.

Cancer discovery

Avec: Ezra Rosen , Alexander Drilon , Debyani Chakravarty

Precision oncology using organoids of a secretory carcinoma of the salivary gland treated with TRK-inhibitors.

Oral oncology

Avec: Gerben Lassche , Adriana C H van Engen-van Grunsven , Onno van Hooij , Tilly W Aalders , Jetty Am Weijers , Emiliano Cocco , Alexander Drilon , Alexander Hoischen , Kornelia Neveling , Jack A Schalken , Gerald W Verhaegh , Carla M L van Herpen

A demand-offer critical analysis of current drug development. Phase I drugs versus TCGA sequencing data.

European journal of cancer (Oxford, England : 1990)

Avec: Matteo Repetto , Edoardo Crimini , Carmen Belli , Luca Boscolo Bielo , Liliana Ascione , Funda Meric-Bernstam , Alexander Drilon , Giuseppe Curigliano

NTRK gene fusion testing and management in lung cancer.

Cancer treatment reviews

Avec: Matteo Repetto , Marina Chiara Garassino , Herbert H Loong , Fernando Lopez-Rios , Tony Mok , Solange Peters , David Planchard , Sanjay Popat , Erin R Rudzinski , Alexander Drilon , Caicun Zhou

Mitogen-Activated Pathway Kinase Inhibitor-Associated Retinopathy: Do Features Differ with Upstream versus Downstream Inhibition?

Ocular oncology and pathology

Avec: Jasmine H Francis , William Foulsham , Julia Canestraro , James J Harding , Eli L Diamond , Alexander Drilon , David H Abramson

Intratumoral Escherichia Is Associated With Improved Survival to Single-Agent Immune Checkpoint Inhibition in Patients With Advanced Non-Small-Cell Lung Cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Avec: Arielle Elkrief , Meagan Montesion , Smruthy Sivakumar , Caryn Hale , Anita S Bowman , Ayyüce Begüm Bektaş , Martina Bradic , Wenfei Kang , Eric Chan , Pooja Gogia , Katia Manova-Todorova , Douglas A Mata , Jacklynn V Egger , Hira Rizvi , Nicolas D Socci , Daniel W Kelly , Eric Rosiek , Fanli Meng , Grittney Tam , Ning Fan , Alexander Drilon , Helena A Yu , Gregory J Riely , Natasha Rekhtman , Álvaro Quintanal Villalonga , Snjezana Dogan , Umesh Bhanot , Mithat Gönen , Brian Loomis , Matthew D Hellmann , Adam J Schoenfeld , Marc Ladanyi , Charles M Rudin , Chad M Vanderbilt

ROS1-dependent cancers - biology, diagnostics and therapeutics.

Nature reviews. Clinical oncology

Avec: Alexander Drilon , Chelsea Jenkins , Sudarshan Iyer , Adam Schoenfeld , Clare Keddy , Monika A Davare

TRK inhibitors in TRK fusion-positive cancers.

Annals of oncology : official journal of the European Society for Medical Oncology

Avec: A Drilon

Entrectinib in patients with advanced or metastatic NTRK fusion-positive solid tumours: integrated analysis of three phase 1-2 trials.

The Lancet. Oncology

Avec: Robert C Doebele , Alexander Drilon , Luis Paz-Ares , Salvatore Siena , Alice T Shaw , Anna F Farago , Collin M Blakely , Takashi Seto , Byung Chul Cho , Diego Tosi , Benjamin Besse , Sant P Chawla , Lyudmila Bazhenova , John C Krauss , Young Kwang Chae , Minal Barve , Ignacio Garrido-Laguna , Stephen V Liu , Paul Conkling , Thomas John , Marwan Fakih , Darren Sigal , Herbert H Loong , Gary L Buchschacher , Pilar Garrido , Jorge Nieva , Conor Steuer , Tobias R Overbeck , Daniel W Bowles , Elizabeth Fox , Todd Riehl , Edna Chow-Maneval , Brian Simmons , Na Cui , Ann Johnson , Susan Eng , Timothy R Wilson , George D Demetri , Auteur inconnu

State-of-the-Art Strategies for Targeting

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Avec: Vivek Subbiah , Dong Yang , Vamsidhar Velcheti , Alexander Drilon , Funda Meric-Bernstam

NTRK fusion detection across multiple assays and 33,997 cases: diagnostic implications and pitfalls.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

Avec: James P Solomon , Irina Linkov , Andrea Rosado , Kerry Mullaney , Ezra Y Rosen , Denise Frosina , Achim A Jungbluth , Ahmet Zehir , Ryma Benayed , Alexander Drilon , David M Hyman , Marc Ladanyi , Anthony N Sireci , Jaclyn F Hechtman

The repertoire of genetic alterations in salivary duct carcinoma including a novel HNRNPH3-ALK rearrangement.

Human pathology

Avec: Snjezana Dogan , Charlotte K Y Ng , Bin Xu , Rahul Kumar , Lu Wang , Marcia Edelweiss , Sasinya N Scott , Ahmet Zehir , Alexander Drilon , Luc G T Morris , Nancy Y Lee , Cristina R Antonescu , Alan L Ho , Nora Katabi , Michael F Berger , Jorge S Reis-Filho

High Yield of RNA Sequencing for Targetable Kinase Fusions in Lung Adenocarcinomas with No Mitogenic Driver Alteration Detected by DNA Sequencing and Low Tumor Mutation Burden.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Ryma Benayed , Michael Offin , Kerry Mullaney , Purvil Sukhadia , Kelly Rios , Patrice Desmeules , Ryan Ptashkin , Helen Won , Jason Chang , Darragh Halpenny , Alison M Schram , Charles M Rudin , David M Hyman , Maria E Arcila , Michael F Berger , Ahmet Zehir , Mark G Kris , Alexander Drilon , Marc Ladanyi

MET IHC Is a Poor Screen for MET Amplification or MET Exon 14 Mutations in Lung Adenocarcinomas: Data from a Tri-Institutional Cohort of the Lung Cancer Mutation Consortium.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

Avec: Robin Guo , Lynne D Berry , Dara L Aisner , Jamie Sheren , Theresa Boyle , Paul A Bunn , Bruce E Johnson , David J Kwiatkowski , Alexander Drilon , Lynette M Sholl , Mark G Kris

A Prospective Study of Circulating Tumor DNA to Guide Matched Targeted Therapy in Lung Cancers.

Journal of the National Cancer Institute

Avec: Joshua K Sabari , Michael Offin , Dennis Stephens , Andy Ni , Adrian Lee , Nick Pavlakis , Stephen Clarke , Connie I Diakos , Sutirtha Datta , Nidhi Tandon , Andres Martinez , Mackenzie L Myers , Alex Makhnin , Ysleni Leger , Helena A Yu , Paul K Paik , Jamie E Chaft , Mark G Kris , Jeong O Jeon , Laetitia A Borsu , Marc Ladanyi , Maria E Arcila , Jennifer Hernandez , Samantha Henderson , Tristan Shaffer , Kavita Garg , Dan DiPasquo , Christopher K Raymond , Lee P Lim , Mark Li , Matthew D Hellmann , Alexander Drilon , Gregory J Riely , Valerie W Rusch , David R Jones , Andreas Rimner , Charles M Rudin , James M Isbell , Bob T Li

Spectrum of Mechanisms of Resistance to Crizotinib and Lorlatinib in

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Jessica J Lin , Noura J Choudhury , Satoshi Yoda , Viola W Zhu , Ted W Johnson , Ramin Sakhtemani , Ibiayi Dagogo-Jack , Subba R Digumarthy , Charlotte Lee , Andrew Do , Jennifer Peterson , Kylie Prutisto-Chang , Wafa Malik , Harper G Hubbeling , Adam Langenbucher , Adam J Schoenfeld , Christina J Falcon , Jennifer S Temel , Lecia V Sequist , Beow Y Yeap , Jochen K Lennerz , Alice T Shaw , Michael S Lawrence , Sai-Hong Ignatius Ou , Aaron N Hata , Alexander Drilon , Justin F Gainor

TRK xDFG Mutations Trigger a Sensitivity Switch from Type I to II Kinase Inhibitors.

Cancer discovery

Avec: Emiliano Cocco , Ji Eun Lee , Srinivasaraghavan Kannan , Alison M Schram , Helen H Won , Sophie Shifman , Amanda Kulick , Laura Baldino , Eneda Toska , Amaia Arruabarrena-Aristorena , Srushti Kittane , Fan Wu , Yanyan Cai , Sabrina Arena , Benedetta Mussolin , Ram Kannan , Neil Vasan , Alexander N Gorelick , Michael F Berger , Ofra Novoplansky , Sankar Jagadeeshan , Yi Liao , Uwe Rix , Sandra Misale , Barry S Taylor , Alberto Bardelli , Jaclyn F Hechtman , David M Hyman , Moshe Elkabets , Elisa de Stanchina , Chandra S Verma , Andrea Ventura , Alexander Drilon , Maurizio Scaltriti

Overcoming MET-Dependent Resistance to Selective RET Inhibition in Patients with RET Fusion-Positive Lung Cancer by Combining Selpercatinib with Crizotinib.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Ezra Y Rosen , Melissa L Johnson , Sarah E Clifford , Romel Somwar , Jennifer F Kherani , Jieun Son , Arrien A Bertram , Monika A Davare , Eric Gladstone , Elena V Ivanova , Dahlia N Henry , Elaine M Kelley , Mika Lin , Marina S D Milan , Binoj C Nair , Elizabeth A Olek , Jenna E Scanlon , Morana Vojnic , Kevin Ebata , Jaclyn F Hechtman , Bob T Li , Lynette M Sholl , Barry S Taylor , Marc Ladanyi , Pasi A Jänne , S Michael Rothenberg , Alexander Drilon , Geoffrey R Oxnard

Updated Integrated Analysis of the Efficacy and Safety of Entrectinib in Locally Advanced or Metastatic

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Avec: Rafal Dziadziuszko , Matthew G Krebs , Filippo De Braud , Salvatore Siena , Alexander Drilon , Robert C Doebele , Manish R Patel , Byoung Chul Cho , Stephen V Liu , Myung-Ju Ahn , Chao-Hua Chiu , Anna F Farago , Chia-Chi Lin , Christos S Karapetis , Yu-Chung Li , Bann-Mo Day , David Chen , Timothy R Wilson , Fabrice Barlesi

NTRK kinase domain mutations in cancer variably impact sensitivity to type I and type II inhibitors.

Communications biology

Avec: Romel Somwar , Nicolle E Hofmann , Bryan Smith , Igor Odintsov , Morana Vojnic , Irina Linkov , Ashley Tam , Inna Khodos , Marissa S Mattar , Elisa de Stanchina , Daniel Flynn , Marc Ladanyi , Alexander Drilon , Ujwal Shinde , Monika A Davare

Response to Immune Checkpoint Inhibition as Monotherapy or in Combination With Chemotherapy in Metastatic

JTO clinical and research reports

Avec: Noura J Choudhury , Jaime L Schneider , Tejas Patil , Viola W Zhu , Debra A Goldman , Soo-Ryum Yang , Christina J Falcon , Andrew Do , Yunan Nie , Andrew J Plodkowski , Jamie E Chaft , Subba R Digumarthy , Natasha Rekhtman , Maria E Arcila , Alexia Iasonos , Sai-Hong I Ou , Jessica J Lin , Alexander Drilon

Zenocutuzumab, a HER2xHER3 Bispecific Antibody, Is Effective Therapy for Tumors Driven by NRG1 Gene Rearrangements.

Cancer discovery

Avec: Alison M Schram , Igor Odintsov , Madelyn Espinosa-Cotton , Inna Khodos , Whitney J Sisso , Marissa S Mattar , Allan J W Lui , Morana Vojnic , Sara H Shameem , Thrusha Chauhan , Jean Torrisi , Jim Ford , Marie N O'Connor , Cecile A W Geuijen , Ron C J Schackmann , Jeroen J Lammerts van Bueren , Ernesto Wasserman , Elisa de Stanchina , Eileen M O'Reilly , Marc Ladanyi , Alexander Drilon , Romel Somwar

Updated Integrated Analysis of the Efficacy and Safety of Entrectinib in Patients With NTRK Fusion-Positive Solid Tumors.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: George D Demetri , Filippo De Braud , Alexander Drilon , Salvatore Siena , Manish R Patel , Byoung Chul Cho , Stephen V Liu , Myung-Ju Ahn , Chao-Hua Chiu , Jessica J Lin , Koichi Goto , Jeeyun Lee , Lyudmila Bazhenova , Thomas John , Marwan Fakih , Sant P Chawla , Rafal Dziadziuszko , Takashi Seto , Sebastian Heinzmann , Bethany Pitcher , David Chen , Timothy R Wilson , Christian Rolfo

Hypersensitivity Reactions to Selpercatinib Treatment With or Without Prior Immune Checkpoint Inhibitor Therapy in Patients With NSCLC in LIBRETTO-001.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

Avec: Caroline E McCoach , Christian Rolfo , Alexander Drilon , Mario Lacouture , Benjamin Besse , Koichi Goto , Viola W Zhu , Daniel S W Tan , Stephanie Farajian , Laura A Potter , Jennifer F Kherani , Victoria Soldatenkova , Elizabeth A Olek , Catherine E Muehlenbein , Keunchil Park

Clinical Utility and Performance of an Ultrarapid Multiplex RNA-Based Assay for Detection of ALK, ROS1, RET, and NTRK1/2/3 Rearrangements and MET Exon 14 Skipping Alterations.

The Journal of molecular diagnostics : JMD

Avec: Ying-Hsia Chu , Jada Barbee , Soo-Ryum Yang , Jason C Chang , Priscilla Liang , Kerry Mullaney , Roger Chan , Paulo Salazar , Ryma Benayed , Michael Offin , Alexander Drilon , Marc Ladanyi , Khedoudja Nafa , Maria E Arcila

Efficacy and safety of larotrectinib in TRK fusion-positive primary central nervous system tumors.

Neuro-oncology

Avec: François Doz , Cornelis M van Tilburg , Birgit Geoerger , Martin Højgaard , Ingrid Øra , Valentina Boni , Michael Capra , Julia Chisholm , Hyun Cheol Chung , Steven G DuBois , Soledad Gallego-Melcon , Nicolas U Gerber , Hiroaki Goto , Juneko E Grilley-Olson , Jordan R Hansford , David S Hong , Antoine Italiano , Hyoung Jin Kang , Karsten Nysom , Anne Thorwarth , Joanna Stefanowicz , Makoto Tahara , David S Ziegler , Igor T Gavrilovic , Ricarda Norenberg , Laura Dima , Esther De La Cuesta , Theodore W Laetsch , Alexander Drilon , Sebastien Perreault

The evolution of RET inhibitor resistance in RET-driven lung and thyroid cancers.

Nature communications

Avec: Ezra Y Rosen , Helen H Won , Youyun Zheng , Emiliano Cocco , Duygu Selcuklu , Yixiao Gong , Noah D Friedman , Ino de Bruijn , Onur Sumer , Craig M Bielski , Casey Savin , Caitlin Bourque , Christina Falcon , Nikeysha Clarke , Xiaohong Jing , Fanli Meng , Catherine Zimel , Sophie Shifman , Srushti Kittane , Fan Wu , Marc Ladanyi , Kevin Ebata , Jennifer Kherani , Barbara J Brandhuber , James Fagin , Eric J Sherman , Natasha Rekhtman , Michael F Berger , Maurizio Scaltriti , David M Hyman , Barry S Taylor , Alexander Drilon

MYC Promotes Tyrosine Kinase Inhibitor Resistance in ROS1-Fusion-Positive Lung Cancer.

Molecular cancer research : MCR

Avec: Sudarshan R Iyer , Igor Odintsov , Adam J Schoenfeld , Evan Siau , Marissa S Mattar , Elisa de Stanchina , Inna Khodos , Alexander Drilon , Gregory J Riely , Marc Ladanyi , Romel Somwar , Monika A Davare

Reversion mutations in germline BRCA1/2-mutant tumors reveal a BRCA-mediated phenotype in non-canonical histologies.

Nature communications

Avec: Yonina R Murciano-Goroff , Alison M Schram , Ezra Y Rosen , Helen Won , Yixiao Gong , Anne Marie Noronha , Yelena Y Janjigian , Zsofia K Stadler , Jason C Chang , Soo-Ryum Yang , Diana Mandelker , Kenneth Offit , Michael F Berger , Mark T A Donoghue , Chaitanya Bandlamudi , Alexander Drilon

Avec: Shivaani Kummar , Lin Shen , David S Hong , Ray McDermott , Vicki L Keedy , Michela Casanova , George D Demetri , Afshin Dowlati , Soledad Gallego Melcón , Ulrik N Lassen , Serge Leyvraz , Tianshu Liu , Victor Moreno , Jyoti Patel , Tejas Patil , Atrayee Basu Mallick , Nuno Sousa , Makoto Tahara , David S Ziegler , Ricarda Norenberg , Pierre Arvis , Nicoletta Brega , Alexander Drilon , Daniel S W Tan

Precision Oncology: 2023 in Review.

Cancer discovery

Avec: Yonina R Murciano-Goroff , Sarah P Suehnholz , Alexander Drilon , Debyani Chakravarty

TKI Type Switching Overcomes ROS1 L2086F in ROS1 Fusion-Positive Cancers.

bioRxiv : the preprint server for biology

Avec: Rajat Thawani , Matteo Repetto , Clare Keddy , Katelyn Nicholson , Kristen Jones , Kevin Nusser , Catherine Z Beach , Guilherme Harada , Alexander Drilon , Monika A Davare

NVL-655 Is a Selective and Brain-Penetrant Inhibitor of Diverse ALK-Mutant Oncoproteins, Including Lorlatinib-Resistant Compound Mutations.

Cancer discovery

Avec: Jessica J Lin , Joshua C Horan , Anupong Tangpeerachaikul , Aurélie Swalduz , Augusto Valdivia , Melissa L Johnson , Benjamin Besse , D Ross Camidge , Toshio Fujino , Satoshi Yoda , Linh Nguyen-Phuong , Hayato Mizuta , Ludovic Bigot , Catline Nobre , Jii Bum Lee , Mi Ra Yu , Scot Mente , Yuting Sun , Nancy E Kohl , James R Porter , Matthew D Shair , Viola W Zhu , Enriqueta Felip , Byoung Chul Cho , Luc Friboulet , Aaron N Hata , Henry E Pelish , Alexander Drilon

Repotrectinib: Redefining the therapeutic landscape for patients with ROS1 fusion-driven non-small cell lung cancer.

Clinical and translational medicine

Avec: Antoine Desilets , Matteo Repetto , Alexander Drilon

Larotrectinib versus Prior Therapies in Tropomyosin Receptor Kinase Fusion Cancer: An Intra-Patient Comparative Analysis.

Cancers

Avec: Antoine Italiano , Shivani Nanda , Andrew Briggs , Jesus Garcia-Foncillas , Ulrik Lassen , Gilles Vassal , Shivaani Kummar , Cornelis M van Tilburg , David S Hong , Theodore W Laetsch , Karen Keating , John A Reeves , Marc Fellous , Barrett H Childs , Alexander Drilon , David M Hyman

Immune checkpoint inhibitors for patients with advanced lung cancer and oncogenic driver alterations: results from the IMMUNOTARGET registry.

Annals of oncology : official journal of the European Society for Medical Oncology

Avec: J Mazieres , A Drilon , A Lusque , L Mhanna , A B Cortot , L Mezquita , A A Thai , C Mascaux , S Couraud , R Veillon , M Van den Heuvel , J Neal , N Peled , M Früh , T L Ng , V Gounant , S Popat , J Diebold , J Sabari , V W Zhu , S I Rothschild , P Bironzo , A Martinez-Marti , A Curioni-Fontecedro , R Rosell , M Lattuca-Truc , M Wiesweg , B Besse , B Solomon , F Barlesi , R D Schouten , H Wakelee , D R Camidge , G Zalcman , S Novello , S I Ou , J Milia , O Gautschi

Frequency and outcomes of brain metastases in patients with HER2-mutant lung cancers.

Cancer

Avec: Michael Offin , Daniel Feldman , Ai Ni , Mackenzie L Myers , W Victoria Lai , Elena Pentsova , Adrienne Boire , Mariza Daras , Emmet J Jordan , David B Solit , Maria E Arcila , David R Jones , James M Isbell , Kathryn Beal , Robert J Young , Charles M Rudin , Gregory J Riely , Alexander Drilon , Viviane Tabar , Lisa M DeAngelis , Helena A Yu , Mark G Kris , Bob T Li

Activating mutations in CSF1R and additional receptor tyrosine kinases in histiocytic neoplasms.

Nature medicine

Avec: Benjamin H Durham , Estibaliz Lopez Rodrigo , Jennifer Picarsic , David Abramson , Veronica Rotemberg , Steven De Munck , Erwin Pannecoucke , Sydney X Lu , Alessandro Pastore , Akihide Yoshimi , Diana Mandelker , Ozge Ceyhan-Birsoy , Gary A Ulaner , Michael Walsh , Mariko Yabe , Kseniya Petrova-Drus , Maria E Arcila , Marc Ladanyi , David B Solit , Michael F Berger , David M Hyman , Mario E Lacouture , Caroline Erickson , Ruth Saganty , Michelle Ki , Ira J Dunkel , Vicente Santa-María López , Jaume Mora , Julien Haroche , Jean-Francois Emile , Olivier Decaux , Frederic Geissmann , Savvas N Savvides , Alexander Drilon , Eli L Diamond , Omar Abdel-Wahab

Repotrectinib Exhibits Potent Antitumor Activity in Treatment-Naïve and Solvent-Front-Mutant ROS1-Rearranged Non-Small Cell Lung Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Mi Ran Yun , Dong Hwi Kim , Seok-Young Kim , Hyeong-Seok Joo , You Won Lee , Hun Mi Choi , Chae Won Park , Seong Gu Heo , Han Na Kang , Sung Sook Lee , Adam J Schoenfeld , Alexander Drilon , Seok-Gu Kang , Hyo Sup Shim , Min Hee Hong , J Jean Cui , Hye Ryun Kim , Byoung Chul Cho

Efficacy of Selpercatinib in

The New England journal of medicine

Avec: Alexander Drilon , Geoffrey R Oxnard , Daniel S W Tan , Herbert H F Loong , Melissa Johnson , Justin Gainor , Caroline E McCoach , Oliver Gautschi , Benjamin Besse , Byoung C Cho , Nir Peled , Jared Weiss , Yu-Jung Kim , Yuichiro Ohe , Makoto Nishio , Keunchil Park , Jyoti Patel , Takashi Seto , Tomohiro Sakamoto , Ezra Rosen , Manisha H Shah , Fabrice Barlesi , Philippe A Cassier , Lyudmila Bazhenova , Filippo De Braud , Elena Garralda , Vamsidhar Velcheti , Miyako Satouchi , Kadoaki Ohashi , Nathan A Pennell , Karen L Reckamp , Grace K Dy , Jürgen Wolf , Benjamin Solomon , Gerald Falchook , Kevin Ebata , Michele Nguyen , Binoj Nair , Edward Y Zhu , Luxi Yang , Xin Huang , Elizabeth Olek , S Michael Rothenberg , Koichi Goto , Vivek Subbiah

MAPK Pathway Alterations Correlate with Poor Survival and Drive Resistance to Therapy in Patients with Lung Cancers Driven by

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Hiroki Sato , Adam J Schoenfeld , Evan Siau , Yue Christine Lu , Huichun Tai , Ken Suzawa , Daisuke Kubota , Allan J W Lui , Besnik Qeriqi , Marissa Mattar , Michael Offin , Masakiyo Sakaguchi , Shinichi Toyooka , Alexander Drilon , Neal X Rosen , Mark G Kris , David Solit , Elisa De Stanchina , Monika A Davare , Gregory J Riely , Marc Ladanyi , Romel Somwar

Clinicopathologic Features and Response to Therapy of

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Avec: Alexander Drilon , Michael Duruisseaux , Ji-Youn Han , Masaoki Ito , Christina Falcon , Soo-Ryum Yang , Yonina R Murciano-Goroff , Haiquan Chen , Morihito Okada , Miguel Angel Molina , Marie Wislez , Philippe Brun , Clarisse Dupont , Eva Branden , Giulio Rossi , Alexa Schrock , Siraj Ali , Valérie Gounant , Fanny Magne , Torsten Gerriet Blum , Alison M Schram , Isabelle Monnet , Jin-Yuan Shih , Joshua Sabari , Maurice Pérol , Viola W Zhu , Misako Nagasaka , Robert Doebele , D Ross Camidge , Maria Arcila , Sai-Hong Ignatius Ou , Denis Moro-Sibilot , Rafael Rosell , Lucia Anna Muscarella , Stephen V Liu , Jacques Cadranel

Clinical utility of next-generation sequencing-based ctDNA testing for common and novel ALK fusions.

Lung cancer (Amsterdam, Netherlands)

Avec: Sebastian Mondaca , Emily S Lebow , Azadeh Namakydoust , Pedram Razavi , Jorge S Reis-Filho , Ronglai Shen , Michael Offin , Hai-Yan Tu , Yonina Murciano-Goroff , Chongrui Xu , Alex Makhnin , Andres Martinez , Nick Pavlakis , Stephen Clarke , Malinda Itchins , Adrian Lee , Andreas Rimner , Daniel Gomez , Gaetano Rocco , Jamie E Chaft , Gregory J Riely , Charles M Rudin , David R Jones , Mark Li , Tristan Shaffer , Seyed Ali Hosseini , Caterina Bertucci , Lee P Lim , Alexander Drilon , Michael F Berger , Ryma Benayed , Maria E Arcila , James M Isbell , Bob T Li

Diagnostic testing approaches for the identification of patients with TRK fusion cancer prior to enrollment in clinical trials investigating larotrectinib.

Cancer genetics

Avec: Erin R Rudzinski , Jaclyn Hechtman , Sinchita Roy-Chowdhuri , Marion Rudolph , Christina M Lockwood , Josh Silvertown , Justyna Wierzbinska , Kui Shen , Ricarda Norenberg , Hendrik Nogai , David S Hong , Alexander Drilon , Theodore W Laetsch

Brief Report: Chylothorax and Chylous Ascites During RET Tyrosine Kinase Inhibitor Therapy.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

Avec: Or Kalchiem-Dekel , Christina J Falcon , Christine M Bestvina , Dazhi Liu , Lauren A Kaplanis , Clare Wilhelm , Jordan Eichholz , Guilherme Harada , Lori J Wirth , Subba R Digumarthy , Robert P Lee , David Kadosh , Robin B Mendelsohn , Jessica Donington , Justin F Gainor , Alexander Drilon , Jessica J Lin

Réseau de co-auteurs

Marc Ladanyi 22 collaborations

David M Hyman 13 collaborations

Alison M Schram 12 collaborations

Maria E Arcila 12 collaborations

Bob T Li 10 collaborations

Michael Offin 10 collaborations

Michael F Berger 10 collaborations

Ryma Benayed 9 collaborations

Soo-Ryum Yang 9 collaborations

Charles M Rudin 9 collaborations

Mark G Kris 9 collaborations

Emiliano Cocco 8 collaborations

Jaclyn F Hechtman 8 collaborations

A Drilon 8 collaborations

Natasha Rekhtman 8 collaborations

Gregory J Riely 8 collaborations

Jessica J Lin 8 collaborations

David S Hong 7 collaborations

Monika A Davare 7 collaborations

Elisa de Stanchina 7 collaborations

Romel Somwar 7 collaborations

Ezra Y Rosen 7 collaborations

Yonina R Murciano-Goroff 7 collaborations

Maurizio Scaltriti 6 collaborations

Theodore W Laetsch 6 collaborations

Benjamin Besse 6 collaborations

Guilherme Harada 6 collaborations

Stephen V Liu 6 collaborations

James J Harding 5 collaborations

Ahmet Zehir 5 collaborations

Kerry Mullaney 5 collaborations

Shivaani Kummar 5 collaborations

Erin R Rudzinski 5 collaborations

David R Jones 5 collaborations

James M Isbell 5 collaborations

Ricarda Norenberg 5 collaborations

Vivek Subbiah 5 collaborations

Koichi Goto 5 collaborations

Christina Falcon 5 collaborations

Matteo Repetto 5 collaborations

Kevin Ebata 5 collaborations

Barry S Taylor 5 collaborations

Robin Guo 5 collaborations

Byoung Chul Cho 5 collaborations

Adam J Schoenfeld 5 collaborations

Viola W Zhu 5 collaborations

Cornelis M van Tilburg 4 collaborations

Makoto Tahara 4 collaborations

Igor Odintsov 4 collaborations

Morana Vojnic 4 collaborations

Marissa S Mattar 4 collaborations

Inna Khodos 4 collaborations

Valerie W Rusch 4 collaborations

Daniel S W Tan 4 collaborations

Ulrik N Lassen 4 collaborations

Pedram Razavi 4 collaborations

Jürgen Wolf 4 collaborations

Christina J Falcon 4 collaborations

Jason Chang 4 collaborations

Sophie Shifman 4 collaborations

Helen H Won 4 collaborations

David B Solit 4 collaborations

Snjezana Dogan 4 collaborations

Jason C Chang 4 collaborations

Rona Yaeger 3 collaborations

Khedoudja Nafa 3 collaborations

Zsofia K Stadler 3 collaborations

D M Hyman 3 collaborations

B T Li 3 collaborations

M Offin 3 collaborations

Anna F Farago 3 collaborations

Birgit Geoerger 3 collaborations

Ray McDermott 3 collaborations

Shivani Nanda 3 collaborations

Barrett H Childs 3 collaborations

Sandra Misale 3 collaborations

Serge Leyvraz 3 collaborations

Laura Dima 3 collaborations

Nicoletta Brega 3 collaborations

Lin Shen 3 collaborations

Victor Moreno 3 collaborations

Tejas Patil 3 collaborations

Alan L Ho 3 collaborations

Oliver Gautschi 3 collaborations

Benjamin J Solomon 3 collaborations

Keunchil Park 3 collaborations

Victoria Soldatenkova 3 collaborations

Sylwia Szymczak 3 collaborations

Andreas Rimner 3 collaborations

Alexia Iasonos 3 collaborations

Lynette M Sholl 3 collaborations

Amanda Kulick 3 collaborations

Alberto Bardelli 3 collaborations

Eneda Toska 3 collaborations

Andres Martinez 3 collaborations

Satoshi Yoda 3 collaborations

Justin F Gainor 3 collaborations

Geoffrey R Oxnard 3 collaborations

S Michael Rothenberg 3 collaborations

Yixiao Gong 3 collaborations

Matthew D Hellmann 3 collaborations

Helen Won 3 collaborations

Funda Meric-Bernstam 3 collaborations

Debyani Chakravarty 3 collaborations

Fanli Meng 3 collaborations

D Ross Camidge 3 collaborations

Rafal Dziadziuszko 3 collaborations

Vamsidhar Velcheti 3 collaborations

Helena A Yu 3 collaborations

Salvatore Siena 3 collaborations

Takashi Seto 3 collaborations

Lyudmila Bazhenova 3 collaborations

Timothy R Wilson 3 collaborations

George D Demetri 3 collaborations

Jamie E Chaft 3 collaborations

Subba R Digumarthy 3 collaborations

Filippo De Braud 3 collaborations

Martin H Voss 2 collaborations

Ghassan K Abou-Alfa 2 collaborations

Scott J Antonia 2 collaborations

Fernando C Santini 2 collaborations

C J Falcon 2 collaborations

Steven G DuBois 2 collaborations

Leo Mascarenhas 2 collaborations

Afshin Dowlati 2 collaborations

François Doz 2 collaborations

Jyoti D Patel 2 collaborations

Russell J Schilder 2 collaborations

Alex Friedlaender 2 collaborations

Alfredo Addeo 2 collaborations

Huichun Tai 2 collaborations

Eric Gladstone 2 collaborations

Ken Suzawa 2 collaborations

Douglas A Mata 2 collaborations

Denise Frosina 2 collaborations

Achim A Jungbluth 2 collaborations

Kay See Tan 2 collaborations

Francisco Sanchez-Vega 2 collaborations

Prasad S Adusumilli 2 collaborations

Gaetano Rocco 2 collaborations

Benjamin Solomon 2 collaborations

Marcia S Brose 2 collaborations

Juneko E Grilley-Olson 2 collaborations

Chaitanya Bandlamudi 2 collaborations

Daniel R Gomez 2 collaborations

Dazhi Liu 2 collaborations

Clare Wilhelm 2 collaborations

John A Reeves 2 collaborations

Marc Fellous 2 collaborations

Gilles Vassal 2 collaborations

Andrea Ventura 2 collaborations

Adam Schoenfeld 2 collaborations

Jordan Eichholz 2 collaborations

Kavita Garg 2 collaborations

Nancy Y Lee 2 collaborations

Brian B Tuch 2 collaborations

Lecia V Sequist 2 collaborations

Edward Y Zhu 2 collaborations

Michele Nguyen 2 collaborations

Barbara J Brandhuber 2 collaborations

D Liu 2 collaborations

J J Harding 2 collaborations

M M Gounder 2 collaborations

Debra A Goldman 2 collaborations

James P Solomon 2 collaborations

Jia Luo 2 collaborations

Maria Arcila 2 collaborations

Jacques Cadranel 2 collaborations

Eva Branden 2 collaborations

Parneet Cheema 2 collaborations

Lucia Anna Muscarella 2 collaborations

Solange Peters 2 collaborations

David Planchard 2 collaborations

Hira Rizvi 2 collaborations

Andy Ni 2 collaborations

Nikolaus Schultz 2 collaborations

Ryan Ptashkin 2 collaborations

Marissa Mattar 2 collaborations

Valentina Boni 2 collaborations

Emiliano Calvo 2 collaborations

Gary A Ulaner 2 collaborations

Lillian M Smyth 2 collaborations

Komal Jhaveri 2 collaborations

Gopa Iyer 2 collaborations

Patrice Desmeules 2 collaborations

Joshua K Sabari 2 collaborations

Laetitia Borsu 2 collaborations

William D Travis 2 collaborations

Karen Keating 2 collaborations

Jasmine H Francis 2 collaborations

Julia Canestraro 2 collaborations

David H Abramson 2 collaborations

Sanjay Popat 2 collaborations

Misako Nagasaka 2 collaborations

Enriqueta Felip 2 collaborations

Matthew G Krebs 2 collaborations

Denis Moro-Sibilot 2 collaborations

None None 2 collaborations

Jared Weiss 2 collaborations

Yuichiro Ohe 2 collaborations

Kadoaki Ohashi 2 collaborations

Ezra Rosen 2 collaborations

Herbert H Loong 2 collaborations

Eli L Diamond 2 collaborations

Clare Keddy 2 collaborations

Robert C Doebele 2 collaborations

Alice T Shaw 2 collaborations

Sant P Chawla 2 collaborations

Thomas John 2 collaborations

Marwan Fakih 2 collaborations

Irina Linkov 2 collaborations

Jorge S Reis-Filho 2 collaborations

Adrian Lee 2 collaborations

Nick Pavlakis 2 collaborations

Stephen Clarke 2 collaborations

Mackenzie L Myers 2 collaborations

Alex Makhnin 2 collaborations

Tristan Shaffer 2 collaborations

Lee P Lim 2 collaborations

Mark Li 2 collaborations

Noura J Choudhury 2 collaborations

Andrew Do 2 collaborations

Sai-Hong Ignatius Ou 2 collaborations

Aaron N Hata 2 collaborations

Srushti Kittane 2 collaborations

Fan Wu 2 collaborations

Melissa L Johnson 2 collaborations

Jennifer F Kherani 2 collaborations

Elizabeth A Olek 2 collaborations

Manish R Patel 2 collaborations

Myung-Ju Ahn 2 collaborations

Chao-Hua Chiu 2 collaborations

David Chen 2 collaborations

Fabrice Barlesi 2 collaborations

Allan J W Lui 2 collaborations

Christian Rolfo 2 collaborations

Caroline E McCoach 2 collaborations

Antoine Italiano 2 collaborations

David S Ziegler 2 collaborations

Evan Siau 2 collaborations

Diana Mandelker 2 collaborations

Jyoti Patel 2 collaborations

Andrew X Zhu 1 collaboration

Todd M Bauer 1 collaboration

Toni K Choueiri 1 collaboration

Charles S Fuchs 1 collaboration

Sameera R Wijayawardana 1 collaboration

Xuejing Aimee Wang 1 collaboration

Brian A Moser 1 collaboration

Arantxa Uruñuela 1 collaboration

Volker Wacheck 1 collaboration

Johanna C Bendell 1 collaboration

Suzanne L Topalian 1 collaboration

F Stephen Hodi 1 collaboration

Julie R Brahmer 1 collaboration

Scott N Gettinger 1 collaboration

David C Smith 1 collaboration

David F McDermott 1 collaboration

John D Powderly 1 collaboration

Jeffrey A Sosman 1 collaboration

Michael B Atkins 1 collaboration

Philip D Leming 1 collaboration

David R Spigel 1 collaboration

Jedd D Wolchok 1 collaboration

Richard D Carvajal 1 collaboration

M Brent McHenry 1 collaboration

Fareeda Hosein 1 collaboration

Christopher T Harbison 1 collaboration

Joseph F Grosso 1 collaboration

Mario Sznol 1 collaboration

Jamal Benhamida 1 collaboration

Sumit Middha 1 collaboration

Jinru Shia 1 collaboration

Liying Zhang 1 collaboration

Donna Wong 1 collaboration

Liliana Villafania 1 collaboration

Leonard Saltz 1 collaboration

Ana C Z Gelatti 1 collaboration

D S Ross 1 collaboration

B Liu 1 collaboration

A M Schram 1 collaboration

P Razavi 1 collaboration

S M Lagana 1 collaboration

Y Zhang 1 collaboration

M Scaltriti 1 collaboration

J F Bromberg 1 collaboration

M Ladanyi 1 collaboration

A Zehir 1 collaboration

R Benayed 1 collaboration

S Chandarlapaty 1 collaboration

J F Hechtman 1 collaboration

J Luo 1 collaboration

H Rizvi 1 collaboration

I R Preeshagul 1 collaboration

J V Egger 1 collaboration

D Hoyos 1 collaboration

C Bandlamudi 1 collaboration

C G McCarthy 1 collaboration

A J Schoenfeld 1 collaboration

K C Arbour 1 collaboration

J E Chaft 1 collaboration

R M Daly 1 collaboration

J Eng 1 collaboration

A Iqbal 1 collaboration

W V Lai 1 collaboration

P Lito 1 collaboration

A Namakydoust 1 collaboration

K Ng 1 collaboration

P K Paik 1 collaboration

G J Riely 1 collaboration

C M Rudin 1 collaboration

H A Yu 1 collaboration

M G Zauderer 1 collaboration

M T A Donoghue 1 collaboration

M Łuksza 1 collaboration

B D Greenbaum 1 collaboration

M G Kris 1 collaboration

M D Hellmann 1 collaboration

Catherine M Albert 1 collaboration

Kristoffer S Rohrberg 1 collaboration

Ramamoorthy Nagasubramanian 1 collaboration

Jordan D Berlin 1 collaboration

Noah Federman 1 collaboration

Alberto S Pappo 1 collaboration

Stefan Bielack 1 collaboration

Stefan M Pfister 1 collaboration

Olaf Witt 1 collaboration

Glen J Weiss 1 collaboration

Giuseppe L Banna 1 collaboration

Takuo Hayashi 1 collaboration

Roger S Smith 1 collaboration

Kota Ishizawa 1 collaboration

Allan J W Liu 1 collaboration

Lukas Delasos 1 collaboration

Christopher Kurzatkowski 1 collaboration

Shinji Kohsaka 1 collaboration

Zebing Liu 1 collaboration

Siddharth Kunte 1 collaboration

Emily Cheng 1 collaboration

Umut Aypar 1 collaboration

Gowtham Jayakumaran 1 collaboration

Yanming Zhang 1 collaboration

Gregory D Jones 1 collaboration

Raul Caso 1 collaboration

Brooke Mastrogiacomo 1 collaboration

Yuan Liu 1 collaboration

James G Connolly 1 collaboration

Matthew J Bott 1 collaboration

Daniela Molena 1 collaboration

Smita Sihag 1 collaboration

Kathryn C Arbour 1 collaboration

Neal Rosen 1 collaboration

Piro Lito 1 collaboration

Haiying Zhang 1 collaboration

David C Lyden 1 collaboration

Yongmei Liu 1 collaboration

Lee Rosen 1 collaboration

B J Solomon 1 collaboration

H H Loong 1 collaboration

Y Summers 1 collaboration

Z M Thomas 1 collaboration

P French 1 collaboration

B K Lin 1 collaboration

A Sashegyi 1 collaboration

J Wolf 1 collaboration

J C-H Yang 1 collaboration

Xiuning Le 1 collaboration

Christina Baik 1 collaboration

Jessica Bauman 1 collaboration

Jill Gilbert 1 collaboration

Luis E Raez 1 collaboration

Jennifer M Johnson 1 collaboration

Smita S Chandran 1 collaboration

Jiaqi Ma 1 collaboration

Martin G Klatt 1 collaboration

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