Christoph Springfeld

Affiliations
  • Nationales Centrum für Tumorerkrankungen (NCT), Abt. Medizinische Onkologie Universitätsklinikum Heidelberg, Heidelberg, Germany.

Publications (68)

Quality of life and outcome of patients with metastatic pancreatic cancer receiving first-line chemotherapy with nab-paclitaxel and gemcitabine: Real-life results from the prospective QOLIXANE trial of the Platform for Outcome, Quality of Life and Translational Research on Pancreatic Cancer registry.

International journal of cancer
Avec: Salah-Eddin Al-Batran , Ralf-Dieter Hofheinz , Alexander Reichart , Claudia Pauligk , Caroline Schönherr , Rudolf Schlag , Gabriele Siegler , Steffen Dörfel , Michael Koenigsmann , Mark-Oliver Zahn , Jörg Schubert , Ali Aldaoud , Heinz-Gert Höffkes , Holger Schulz , Lars Hahn , Jens Uhlig , Wolfgang Blau , Martina Stauch , Jörg Weniger , Martin Wolf , Lutz Jacobasch , Stephan Bildat , Jürgen Wehmeyer , Nils Homann , Jörg Trojan , Oliver Waidmann , Thomas Fietz , Hans-Peter Feustel , Matthias Groschek , Jan Wierecky , Karin Waibel , Stefan Mahlmann , Uwe Schwindel , Uwe Peters , Gunter Schuch , Daniel Pink , Henning Eschenburg , Marcus-A Wörns , Hans-Detlev Harich , Ludwig Fischer von Weikersthal , Klaus-Ulrich Däßler , Dirk M Behringer , Helmut Messmann , Albrecht Kretzschmar , Eike Gallmeier , Helmut Forstbauer , Volker Kunzmann , Jens Papke , Petra Büchner-Steudel , Ursula Vehling-Kaiser , Christoph Springfeld , Arndt Vogel , Thomas J Ettrich , Marina Schaaf , Gerrit Zur Hausen , Thorsten Oliver Götze , Auteur inconnu

RNA-Based Detection of Gene Fusions in Formalin-Fixed and Paraffin-Embedded Solid Cancer Samples.

Cancers
Avec: Martina Kirchner , Olaf Neumann , Anna-Lena Volckmar , Fabian Stögbauer , Michael Allgäuer , Daniel Kazdal , Jan Budczies , Eugen Rempel , Regine Brandt , Suranand Babu Talla , Moritz von Winterfeld , Jonas Leichsenring , Tilmann Bochtler , Alwin Krämer , Christoph Springfeld , Peter Schirmacher , Roland Penzel , Volker Endris , Albrecht Stenzinger

Prognostic Impact of Carboxylesterase 2 in Cholangiocarcinoma.

Scientific reports
Avec: Benjamin Goeppert , Marcus Renner , Stephan Singer , Thomas Albrecht , Qiangnu Zhang , Arianeb Mehrabi , Anita Pathil , Christoph Springfeld , Bruno Köhler , Christian Rupp , Karl Heinz Weiss , Anja A Kühl , Ruza Arsenic , Ulrich Frank Pape , Arndt Vogel , Peter Schirmacher , Stephanie Roessler , Nalân Utku

Programmed cell death ligand 1 (PD-L1, CD274) in cholangiocarcinoma - correlation with clinicopathological data and comparison of antibodies.

BMC cancer
Avec: Mark Kriegsmann , Stephanie Roessler , Katharina Kriegsmann , Marcus Renner , Rémi Longuespée , Thomas Albrecht , Moritz Loeffler , Stephan Singer , Arianeb Mehrabi , Monika Nadja Vogel , Anita Pathil , Bruno Köhler , Christoph Springfeld , Christian Rupp , Karl Heinz Weiss , Benjamin Goeppert

Actual Five-year Survival After Upfront Resection for Pancreatic Ductal Adenocarcinoma: Who Beats the Odds?

Annals of surgery
Avec: Oliver Strobel , Philipp Lorenz , Ulf Hinz , Matthias Gaida , Anna-Katharina König , Thomas Hank , Willem Niesen , J Ö Rg Kaiser , Mohammed Al-Saeedi , Frank Bergmann , Christoph Springfeld , Christoph Berchtold , Markus K Diener , Martin Schneider , Arianeb Mehrabi , Beat P Müller-Stich , Thilo Hackert , Dirk Jager , Markus W Büchler

Sequencing of serially passaged measles virus affirms its genomic stability and reveals a nonrandom distribution of consensus mutations.

The Journal of general virology
Avec: Mathias Felix Leber , Birgit Hoyler , Stefanie Prien , Serge Neault , Christine E Engeland , Judith M Förster , Sascha Bossow , Christoph Springfeld , Christof von Kalle , Dirk Jäger , John C Bell , Guy Ungerechts

Distal Bile Duct Cancer: Radical (R0 > 1 mm) Resection Achieves Favorable Survival.

Annals of surgery
Avec: Christine Tjaden , Ulf Hinz , Ulla Klaiber , Ulrike Heger , Christoph Springfeld , Benjamin Goeppert , Thomas Schmidt , Arianeb Mehrabi , Oliver Strobel , Christoph Berchtold , Martin Schneider , Markus Diener , John P Neoptolemos , Thilo Hackert , Markus W Büchler

Repeat liver resection for recurrent intrahepatic cholangiocarcinoma: meta-analysis.

The British journal of surgery
Avec: Ali Ramouz , Sadeq Ali-Hasan-Al-Saegh , Saeed Shafiei , Sanam Fakour , Elias Khajeh , Ali Majlesara , Ali Adeliansedehi , Pascal Probst , Christoph Springfeld , De-Hua Chang , Christian Rupp , Carlos Carvalho , Mohammad Golriz , Katrin Hoffmann , Arianeb Mehrabi

Etiology-independent activation of the LTβ-LTβR-RELB axis drives aggressiveness and predicts poor prognosis in Hepatocellular carcinoma.

Hepatology (Baltimore, Md.)
Avec: Anna-Lena Scherr , Luisa Nader , Kaiyu Xu , Christin Elssner , Dirk A Ridder , Federico Nichetti , Manuel Mastel , Sarah Fritzsche , Eblina Kelmendi , Nathalie Schmitt , Paula Hoffmeister-Wittmann , Sofia M E Weiler , Felix Korell , Thomas Albrecht , Maximilian Schwab , Hanna Isele , Annika Kessler , Jennifer Hüllein , Agnieszka Seretny , Liangtao Ye , Toni Urbanik , Stefan Welte , Anne-Laure Leblond , Christoph E Heilig , Mohammad Rahbari , Adnan Ali , Suchira Gallage , Bénédicte Lenoir , Nina Wilhelm , Ulrike Gärtner , Simon J Ogrodnik , Christoph Springfeld , Darjus Tschaharganeh , Stefan Fröhling , Thomas Longerich , Henning Schulze-Bergkamen , Dirk Jäger , Lydia Brandl , Peter Schirmacher , Beate K Straub , Achim Weber , Enrico N De Toni , Benjamin Goeppert , Mathias Heikenwalder , Rene Jackstadt , Stephanie Roessler , Kai Breuhahn , Bruno C Köhler

Mismatch repair deficiency is a rare but putative therapeutically relevant finding in non-liver fluke associated cholangiocarcinoma.

British journal of cancer
Avec: Benjamin Goeppert , Stephanie Roessler , Marcus Renner , Stephan Singer , Arianeb Mehrabi , Monika Nadja Vogel , Anita Pathil , Elena Czink , Bruno Köhler , Christoph Springfeld , Jan Pfeiffenberger , Christian Rupp , Karl Heinz Weiss , Peter Schirmacher , Magnus von Knebel Doeberitz , Matthias Kloor

Metastatic Acinar Cell Carcinoma of the Pancreas: A Retrospective Cohort Study on Systemic Chemotherapy and Review of the Literature.

Pancreas
Avec: Elena Busch , Wiebke Werft , Nina Bougatf , Thilo Hackert , Dirk Jäger , Christoph Springfeld , Anne Katrin Berger

Integrative analysis reveals early and distinct genetic and epigenetic changes in intraductal papillary and tubulopapillary cholangiocarcinogenesis.

Gut
Avec: Benjamin Goeppert , Damian Stichel , Reka Toth , Sarah Fritzsche , Moritz Anton Loeffler , Anna Melissa Schlitter , Olaf Neumann , Yassen Assenov , Monika Nadja Vogel , Arianeb Mehrabi , Katrin Hoffmann , Bruno Köhler , Christoph Springfeld , Dieter Weichenhan , Christoph Plass , Irene Esposito , Peter Schirmacher , Andreas von Deimling , Stephanie Roessler

Co-expression of YAP and TAZ associates with chromosomal instability in human cholangiocarcinoma.

BMC cancer
Avec: Marcell Tóth , Lilija Wehling , Lena Thiess , Fabian Rose , Jennifer Schmitt , Sofia M E Weiler , Carsten Sticht , Carolina De La Torre , Melina Rausch , Thomas Albrecht , Niels Grabe , Lea Duwe , Jesper B Andersen , Bruno C Köhler , Christoph Springfeld , Arianeb Mehrabi , Yakup Kulu , Peter Schirmacher , Stephanie Roessler , Benjamin Goeppert , Kai Breuhahn

Tertiary lymphoid structures and their association to immune phenotypes and circulatory IL2 levels in pancreatic ductal adenocarcinoma.

Oncoimmunology
Avec: Azaz Ahmed , Sophia Köhler , Rosa Klotz , Nathalia Giese , Thilo Hackert , Christoph Springfeld , Inka Zörnig , Dirk Jäger , Niels Halama

FLOT Versus FLOT/Trastuzumab/Pertuzumab Perioperative Therapy of Human Epidermal Growth Factor Receptor 2-Positive Resectable Esophagogastric Adenocarcinoma: A Randomized Phase II Trial of the AIO EGA Study Group.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Avec: Ralf-Dieter Hofheinz , Kirsten Merx , Georg M Haag , Christoph Springfeld , Thomas Ettrich , Kersten Borchert , Albrecht Kretzschmar , Christian Teschendorf , Gabriele Siegler , Matthias P Ebert , Eray Goekkurt , Rolf Mahlberg , Nils Homann , Daniel Pink , Wolf Bechstein , Peter Reichardt , Hagen Flach , Timo Gaiser , Achim Battmann , Fuat S Oduncu , Maria Loose , Disorn Sookthai , Claudia Pauligk , Thorsten O Göetze , Salah-Eddin Al-Batran

Cytokine release syndrome-like serum responses after COVID-19 vaccination are frequent and clinically inapparent under cancer immunotherapy.

Nature cancer
Avec: Thomas Walle , Sunanjay Bajaj , Joscha A Kraske , Thomas Rösner , Christiane S Cussigh , Katharina A Kälber , Lisa Jasmin Müller , Sophia Boyoung Strobel , Jana Burghaus , Stefan M Kallenberger , Christoph K Stein-Thöringer , Maximilian Jenzer , Antonia Schubert , Steffen Kahle , Anja Williams , Birgit Hoyler , Lin Zielske , Renate Skatula , Stefanie Sawall , Mathias F Leber , Russell Z Kunes , Johannes Krisam , Carlo Fremd , Andreas Schneeweiss , Jürgen Krauss , Leonidas Apostolidis , Anne Katrin Berger , Georg M Haag , Stefanie Zschäbitz , Niels Halama , Christoph Springfeld , Romy Kirsten , Jessica C Hassel , Dirk Jäger , Auteur inconnu , Guy Ungerechts

Immediate surgery compared with short-course neoadjuvant gemcitabine plus capecitabine, FOLFIRINOX, or chemoradiotherapy in patients with borderline resectable pancreatic cancer (ESPAC5): a four-arm, multicentre, randomised, phase 2 trial.

The lancet. Gastroenterology & hepatology
Avec: Paula Ghaneh , Daniel Palmer , Silvia Cicconi , Richard Jackson , Christopher Michael Halloran , Charlotte Rawcliffe , Rajaram Sripadam , Somnath Mukherjee , Zahir Soonawalla , Jonathan Wadsley , Ahmed Al-Mukhtar , Euan Dickson , Janet Graham , Long Jiao , Harpreet S Wasan , Iain S Tait , Andreas Prachalias , Paul Ross , Juan W Valle , Derek A O'Reilly , Bilal Al-Sarireh , Sarah Gwynne , Irfan Ahmed , Kate Connolly , Kein-Long Yim , David Cunningham , Thomas Armstrong , Caroline Archer , Keith Roberts , Yuk Ting Ma , Christoph Springfeld , Christine Tjaden , Thilo Hackert , Markus W Büchler , John P Neoptolemos , Auteur inconnu

Association of perioperative use of statins, metformin, and aspirin with recurrence after curative liver resection in patients with hepatocellular carcinoma: A propensity score matching analysis.

Cancer medicine
Avec: Elias Khajeh , Ehsan Aminizadeh , Arash Dooghaie Moghadam , Ali Ramouz , Rosa Klotz , Mohammad Golriz , Uta Merle , Christoph Springfeld , De-Hua Chang , Thomas Longerich , Markus W Büchler , Arianeb Mehrabi

A phase Ib/II trial of capmatinib plus spartalizumab

JHEP reports : innovation in hepatology
Avec: Armando Santoro , Eric Assenat , Thomas Yau , Jean-Pierre Delord , Michela Maur , Jennifer Knox , Stephane Cattan , Kyung-Hun Lee , Gianluca Del Conte , Christoph Springfeld , Elisa Leo , Alexandros Xyrafas , Lauren Fairchild , Feby Mardjuadi , Stephen L Chan

Lymphotoxin beta-activated LTBR/NIK/RELB axis drives proliferation in cholangiocarcinoma.

Liver international : official journal of the International Association for the Study of the Liver
Avec: Kaiyu Xu , Annika Kessler , Federico Nichetti , Paula Hoffmeister-Wittmann , Anna-Lena Scherr , Luisa Nader , Eblina Kelmendi , Nathalie Schmitt , Maximilian Schwab , María García-Beccaria , Benjamin Sobol , Osama Azzam Nieto , Hanna Isele , Ulrike Gärtner , Nuria Vaquero-Siguero , Julia Volk , Felix Korell , Andreas Mock , Danijela Heide , Pierluigi Ramadori , Bénédicte Lenoir , Thomas Albrecht , Jennifer Hüllein , Dirk Jäger , Stefan Fröhling , Christoph Springfeld , Rene Jackstadt , Mathias Heikenwälder , Michael T Dill , Stephanie Roessler , Benjamin Goeppert , Bruno C Köhler

Impact of interventions and tumor stage on health-related quality of life in patients with hepatocellular carcinoma.

Journal of cancer research and clinical oncology
Avec: Cyrill Wehling , Daniel Hornuss , Pasquale Schneider , Christoph Springfeld , Katrin Hoffmann , De-Hua Chang , Patrick Naumann , Markus Mieth , Thomas Longerich , Clemens Kratochwil , Arianeb Mehrabi , Annika Gauss , Karl Heinz Weiss , Jan Pfeiffenberger

Prognostic significance of microsatellite-instability in gastric and gastroesophageal junction cancer patients undergoing neoadjuvant chemotherapy.

International journal of cancer
Avec: Georg Martin Haag , Elena Czink , Aysel Ahadova , Thomas Schmidt , Leila Sisic , Susanne Blank , Ulrike Heger , Leonidas Apostolidis , Anne Katrin Berger , Christoph Springfeld , Felix Lasitschka , Dirk Jäger , Magnus von Knebel Doeberitz , Matthias Kloor

[Neoadjuvant and adjuvant treatment of pancreatic cancer].

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen
Avec: C Springfeld , T Hackert , D Jäger , M W Büchler , J P Neoptolemos

HER2 gene (ERBB2) amplification is a low-frequency driver with potential predictive value in gallbladder carcinoma.

Virchows Archiv : an international journal of pathology
Avec: Thomas Albrecht , Melina Rausch , Stephanie Roessler , Veronika Geissler , Michael Albrecht , Christine Halske , Carolin Seifert , Marcus Renner , Stephan Singer , Arianeb Mehrabi , Monika Nadja Vogel , Anita Pathil-Warth , Elena Busch , Bruno Köhler , Christian Rupp , Karl Heinz Weiss , Christoph Springfeld , Christoph Röcken , Peter Schirmacher , Benjamin Goeppert

Phase 2 Trial of Oncolytic H-1 Parvovirus Therapy Shows Safety and Signs of Immune System Activation in Patients With Metastatic Pancreatic Ductal Adenocarcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research
Avec: Jacek Hajda , Barbara Leuchs , Assia L Angelova , Veronika Frehtman , Jean Rommelaere , Mieke Mertens , Maximilian Pilz , Meinhard Kieser , Ottheinz Krebs , Michael Dahm , Bernard Huber , Christine E Engeland , Athanasios Mavratzas , Nicolas Hohmann , Jutta Schreiber , Dirk Jäger , Niels Halama , Oliver Sedlaczek , Matthias M Gaida , Volker Daniel , Christoph Springfeld , Guy Ungerechts

Programmed Death Ligand-1 (PD-L1) Is an Independent Negative Prognosticator in Western-World Gallbladder Cancer.

Cancers
Avec: Thomas Albrecht , Fritz Brinkmann , Michael Albrecht , Anke S Lonsdorf , Arianeb Mehrabi , Katrin Hoffmann , Yakup Kulu , Alphonse Charbel , Monika N Vogel , Christian Rupp , Bruno Köhler , Christoph Springfeld , Peter Schirmacher , Stephanie Roessler , Benjamin Goeppert

Peripheral blood and tissue assessment highlights differential tumor-circulatory gradients of IL2 and MIF with prognostic significance in resectable pancreatic ductal adenocarcinoma.

Oncoimmunology
Avec: Azaz Ahmed , Sophia Köhler , Rosa Klotz , Nathalia Giese , Felix Lasitschka , Thilo Hackert , Christoph Springfeld , Inka Zörnig , Dirk Jäger , Niels Halama

Corrigendum: Clinical impact of molecular subtyping of pancreatic cancer.

Frontiers in cell and developmental biology
Avec: Xu Zhou , Kai Hu , Peter Bailey , Christoph Springfeld , Susanne Roth , Roma Kurilov , Benedikt Brors , Thomas Gress , Malte Buchholz , Jingyu An , Kongyuan Wei , Teresa Peccerella , Markus W Büchler , Thilo Hackert , John P Neoptolemos

Durvalumab Plus Gemcitabine and Cisplatin in Patients with Advanced Biliary Tract Cancer: An Exploratory Analysis of Real-World Data.

Targeted oncology
Avec: Alexander Olkus , Aurelie Tomczak , Anne Katrin Berger , Conrad Rauber , Philip Puchas , Cyrill Wehling , Thomas Longerich , Arianeb Mehrabi , De-Hua Chang , Jakob Liermann , Sophia Schäfer , Jan Pfeiffenberger , Dirk Jäger , Patrick Michl , Christoph Springfeld , Michael T Dill

Promising Outcomes of Modified ALPPS for Staged Hepatectomy in Cholangiocarcinoma.

Cancers
Avec: Arianeb Mehrabi , Mohammad Golriz , Ali Ramouz , Elias Khajeh , Ahmed Hammad , Thilo Hackert , Beat Müller-Stich , Oliver Strobel , Sadeq Ali-Hasan-Al-Saegh , Omid Ghamarnejad , Mohammed Al-Saeedi , Christoph Springfeld , Christian Rupp , Philipp Mayer , Markus Mieth , Benjamin Goeppert , Katrin Hoffmann , Markus W Büchler

The phase I/II eNRGy trial: Zenocutuzumab in patients with cancers harboring

Future oncology (London, England)
Avec: Dong-Wan Kim , Alison M Schram , Antoine Hollebecque , Kazumi Nishino , Teresa Macarulla , Sun Young Rha , Michaël Duruisseaux , Stephen V Liu , Mohammed Najeeb Al Hallak , Kumiko Umemoto , Claas Wesseler , James M Cleary , Christoph Springfeld , Cindy Neuzillet , Andrew Joe , Shekeab Jauhari , Jim Ford , Koichi Goto

Bcl-x

Liver international : official journal of the International Association for the Study of the Liver
Avec: Paula Hoffmeister-Wittmann , Andreas Mock , Federico Nichetti , Felix Korell , Christoph E Heilig , Anna-Lena Scherr , Michael Günther , Thomas Albrecht , Eblina Kelmendi , Kaiyu Xu , Luisa Nader , Annika Kessler , Nathalie Schmitt , Sarah Fritzsche , Sofia Weiler , Benjamin Sobol , Albrecht Stenzinger , Stefan Boeck , Christoph B Westphalen , Klaus Schulze-Osthoff , Jörg Trojan , Thomas Kindler , Wilko Weichert , Karsten Spiekermann , Michael Bitzer , Gunnar Folprecht , Anna L Illert , Melanie Boerries , Frederick Klauschen , Sebastian Ochsenreither , Jens Siveke , Sebastian Bauer , Hanno Glimm , Benedikt Brors , Jennifer Hüllein , Daniel Hübschmann , Sebastian Uhrig , Peter Horak , Simon Kreutzfeldt , Jesus M Banales , Christoph Springfeld , Dirk Jäger , Peter Schirmacher , Stephanie Roessler , Steffen Ormanns , Benjamin Goeppert , Stefan Fröhling , Bruno C Köhler

Immune features of the peritumoral stroma in pancreatic ductal adenocarcinoma.

Frontiers in immunology
Avec: Azaz Ahmed , Rosa Klotz , Sophia Köhler , Nathalia Giese , Thilo Hackert , Christoph Springfeld , Dirk Jäger , Niels Halama

Applicability of scoring systems predicting outcome of transarterial chemoembolization for hepatocellular carcinoma.

Journal of cancer research and clinical oncology
Avec: Marie Vogeler , Isabelle Mohr , Jan Pfeiffenberger , Simon David Sprengel , Miriam Klauss , Andreas Teufel , De-Hua Chang , Christoph Springfeld , Thomas Longerich , Uta Merle , Arianeb Mehrabi , Karl Heinz Weiss , Markus Mieth

Successful BRAF/MEK inhibition in a patient with

Cold Spring Harbor molecular case studies
Avec: Elena Busch , Simon Kreutzfeldt , Abbas Agaimy , Gunhild Mechtersheimer , Peter Horak , Benedikt Brors , Barbara Hutter , Martina Fröhlich , Sebastian Uhrig , Philipp Mayer , Evelin Schröck , Albrecht Stenzinger , Hanno Glimm , Dirk Jäger , Christoph Springfeld , Stefan Fröhling , Stefanie Zschäbitz

Cetuximab in Pancreatic Cancer Therapy: A Systematic Review and Meta-Analysis.

Oncology
Avec: Tobias Forster , Felix J Huettner , Christoph Springfeld , Matthias Loehr , Eva Kalkum , Matthes Hackbusch , Thilo Hackert , Markus K Diener , Pascal Probst

Chemotherapy for pancreatic cancer.

Presse medicale (Paris, France : 1983)
Avec: Christoph Springfeld , Dirk Jäger , Markus W Büchler , Oliver Strobel , Thilo Hackert , Daniel H Palmer , John P Neoptolemos

HER2 gene (ERBB2) amplification is a rare event in non-liver-fluke associated cholangiocarcinogenesis.

BMC cancer
Avec: Thomas Albrecht , Melina Rausch , Stephanie Rössler , Michael Albrecht , Jana Dorothea Braun , Veronika Geissler , Arianeb Mehrabi , Monika Nadja Vogel , Anita Pathil-Warth , Gunhild Mechtersheimer , Marcus Renner , Christian Rupp , Karl Heinz Weiss , Elena Busch , Bruno Köhler , Christoph Springfeld , Peter Schirmacher , Benjamin Goeppert

miRNA profiling of biliary intraepithelial neoplasia reveals stepwise tumorigenesis in distal cholangiocarcinoma via the miR-451a/ATF2 axis.

The Journal of pathology
Avec: Moritz A Loeffler , Jun Hu , Martina Kirchner , Xiyang Wei , Yi Xiao , Thomas Albrecht , Carolina De La Torre , Carsten Sticht , Jesus M Banales , Monika N Vogel , Anita Pathil-Warth , Arianeb Mehrabi , Katrin Hoffmann , Christian Rupp , Bruno Köhler , Christoph Springfeld , Peter Schirmacher , Junfang Ji , Stephanie Roessler , Benjamin Goeppert

Clinical Impact of Molecular Subtyping of Pancreatic Cancer.

Frontiers in cell and developmental biology
Avec: Xu Zhou , Kai Hu , Peter Bailey , Christoph Springfeld , Susanne Roth , Roma Kurilov , Benedikt Brors , Thomas Gress , Malte Buchholz , Jingyu An , Kongyuan Wei , Teresa Peccerella , Markus W Büchler , Thilo Hackert , John P Neoptolemos

STAT1 and STAT3 Exhibit a Crosstalk and Are Associated with Increased Inflammation in Hepatocellular Carcinoma.

Cancers
Avec: Carolin Ploeger , Johannes Schreck , Thorben Huth , Angelika Fraas , Thomas Albrecht , Alphonse Charbel , Junfang Ji , Stephan Singer , Kai Breuhahn , Stefan Pusch , Bruno Christian Köhler , Christoph Springfeld , Peter Schirmacher , Arianeb Mehrabi , Benjamin Goeppert , Stephanie Roessler

Clinical effects and safety of different transarterial chemoembolization methods for bridging and palliative treatments in hepatocellular carcinoma.

Journal of cancer research and clinical oncology
Avec: Isabelle Mohr , Marie Vogeler , Jan Pfeiffenberger , Simon David Sprengel , Miriam Klauss , Boris Radeleff , Andreas Teufel , De-Hua Chang , Christoph Springfeld , Thomas Longerich , Uta Merle , Arianeb Mehrabi , Karl Heinz Weiss , Markus Mieth

Statin use is associated with the reduction in hepatocellular carcinoma recurrence after liver surgery.

BMC cancer
Avec: Elias Khajeh , Arash Dooghaie Moghadam , Pegah Eslami , Sadeq Ali-Hasan-Al-Saegh , Ali Ramouz , Saeed Shafiei , Omid Ghamarnejad , Sepehr Abbasi Dezfouli , Christian Rupp , Christoph Springfeld , Carlos Carvalho , Pascal Probst , Seyed Mostafa Mousavizadeh , Arianeb Mehrabi

Repotrectinib in

The New England journal of medicine
Avec: Alexander Drilon , D Ross Camidge , Jessica J Lin , Sang-We Kim , Benjamin J Solomon , Rafal Dziadziuszko , Benjamin Besse , Koichi Goto , Adrianus Johannes de Langen , Jürgen Wolf , Ki Hyeong Lee , Sanjay Popat , Christoph Springfeld , Misako Nagasaka , Enriqueta Felip , Nong Yang , Vamsidhar Velcheti , Shun Lu , Steven Kao , Christophe Dooms , Matthew G Krebs , Wenxiu Yao , Muhammad Shaalan Beg , Xiufeng Hu , Denis Moro-Sibilot , Parneet Cheema , Shanna Stopatschinskaja , Minal Mehta , Denise Trone , Armin Graber , Gregory Sims , Yong Yuan , Byoung Chul Cho , Auteur inconnu

Persister cell phenotypes contribute to poor patient outcomes after neoadjuvant chemotherapy in PDAC.

Nature cancer
Avec: Xu Zhou , Jingyu An , Roma Kurilov , Benedikt Brors , Kai Hu , Teresa Peccerella , Stephanie Roessler , Katrin Pfütze , Angela Schulz , Stephan Wolf , Nicolas Hohmann , Dirk Theile , Max Sauter , Jürgen Burhenne , Shigenori Ei , Ulrike Heger , Oliver Strobel , Simon T Barry , Christoph Springfeld , Christine Tjaden , Frank Bergmann , Markus Büchler , Thilo Hackert , Franco Fortunato , John P Neoptolemos , Peter Bailey

Sex Differences in the Systemic and Local Immune Response of Pancreatic Cancer Patients.

Cancers
Avec: Azaz Ahmed , Sophia Köhler , Rosa Klotz , Nathalia Giese , Thilo Hackert , Christoph Springfeld , Dirk Jäger , Niels Halama

Neoadjuvant therapy for pancreatic cancer.

Nature reviews. Clinical oncology
Avec: Christoph Springfeld , Cristina R Ferrone , Matthew H G Katz , Philip A Philip , Theodore S Hong , Thilo Hackert , Markus W Büchler , John Neoptolemos

Refining the Treatment of Pancreatic Cancer From Big Data to Improved Individual Survival.

Function (Oxford, England)
Avec: Peter Bailey , Xu Zhou , Jingyu An , Teresa Peccerella , Kai Hu , Christoph Springfeld , Markus Büchler , John P Neoptolemos

Deep Learning-Enabled Diagnosis of Liver Adenocarcinoma.

Gastroenterology
Avec: Thomas Albrecht , Annik Rossberg , Jana Dorothea Albrecht , Jan Peter Nicolay , Beate Katharina Straub , Tiemo Sven Gerber , Michael Albrecht , Fritz Brinkmann , Alphonse Charbel , Constantin Schwab , Johannes Schreck , Alexander Brobeil , Christa Flechtenmacher , Moritz von Winterfeld , Bruno Christian Köhler , Christoph Springfeld , Arianeb Mehrabi , Stephan Singer , Monika Nadja Vogel , Olaf Neumann , Albrecht Stenzinger , Peter Schirmacher , Cleo-Aron Weis , Stephanie Roessler , Jakob Nikolas Kather , Benjamin Goeppert

Metavert synergises with standard cytotoxics in human PDAC organoids and is associated with transcriptomic signatures of therapeutic response.

Translational oncology
Avec: Jingyu An , Roma Kurilov , Teresa Peccerella , Frank Bergmann , Mouad Edderkaoui , Adrian Lim , Xu Zhou , Katrin Pfütze , Angela Schulz , Stephan Wolf , Kai Hu , Christoph Springfeld , Sadaf S Mughal , Lenart Zezlina , Franco Fortunato , Georg Beyer , Julia Mayerle , Susanne Roth , Johannes Hulkkonen , Daniela Merz , Shigenori Ei , Arianeb Mehrabi , Martin Loos , Mohammed Al-Saeedi , Christoph W Michalski , Markus W Büchler , Thilo Hackert , Benedikt Brors , Stephen J Pandol , Peter Bailey , John P Neoptolemos

NUC-1031/cisplatin versus gemcitabine/cisplatin in untreated locally advanced/metastatic biliary tract cancer (NuTide:121).

Future oncology (London, England)
Avec: Mairéad Geraldine McNamara , Lipika Goyal , Mark Doherty , Christoph Springfeld , David Cosgrove , Katrin Marie Sjoquist , Joon Oh Park , Helena Verdaguer , Chiara Braconi , Paul J Ross , Aimery De Gramont , John Raymond Zalcberg , Daniel H Palmer , Juan W Valle , Jennifer J Knox

Metastatic adult pancreatoblastoma: Multimodal treatment and molecular characterization of a very rare disease.

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]
Avec: Anne Katrin Berger , Sadaf Shabbir Mughal , Michael Allgäuer , Christoph Springfeld , Thilo Hackert , Tim Frederik Weber , Patrick Naumann , Barbara Hutter , Peter Horak , Arne Jahn , Evelin Schröck , Georg Martin Haag , Leonidas Apostolidis , Dirk Jäger , Albrecht Stenzinger , Stefan Fröhling , Hanno Glimm , Christoph Heining

Induction chemotherapy in pancreatic cancer: CA 19-9 may predict resectability and survival.

HPB : the official journal of the International Hepato Pancreato Biliary Association
Avec: Ulrike Heger , Huihui Sun , Ulf Hinz , Ulla Klaiber , Masayuki Tanaka , Bing Liu , Milena Sachsenmaier , Christoph Springfeld , Christoph W Michalski , Markus W Büchler , Thilo Hackert

Low frequency of mismatch repair deficiency in gallbladder cancer.

Diagnostic pathology
Avec: Benjamin Goeppert , Stephanie Roessler , Marcus Renner , Moritz Loeffler , Stephan Singer , Melina Rausch , Thomas Albrecht , Arianeb Mehrabi , Monika Nadja Vogel , Anita Pathil , Elena Czink , Bruno Köhler , Christoph Springfeld , Christian Rupp , Karl Heinz Weiss , Peter Schirmacher , Magnus von Knebel Doeberitz , Matthias Kloor

Protocol of a prospective, monocentric phase I/II feasibility study investigating the safety of multimodality treatment with a combination of intraoperative chemotherapy and surgical resection in locally confined or borderline resectable pancreatic cancer: the combiCaRe study.

BMJ open
Avec: Susanne Roth , Christoph Springfeld , Markus K Diener , Christine Tjaden , Phillip Knebel , Ulla Klaiber , Christoph W Michalski , Markus Mieth , Dirk Jäger , Markus W Büchler , Thilo Hackert

The Transmembrane Receptor TIRC7 Identifies a Distinct Subset of Immune Cells with Prognostic Implications in Cholangiocarcinoma.

Cancers
Avec: Thomas Albrecht , Benjamin Goeppert , Fritz Brinkmann , Alphonse Charbel , Qiangnu Zhang , Johannes Schreck , Nina Wilhelm , Stephan Singer , Bruno C Köhler , Christoph Springfeld , Arianeb Mehrabi , Peter Schirmacher , Anja A Kühl , Monika N Vogel , Holger Jansen , Nalân Utku , Stephanie Roessler

Association of circulating PLA2G7 levels with cancer cachexia and assessment of darapladib as a therapy.

Journal of cachexia, sarcopenia and muscle
Avec: Pauline Morigny , Doris Kaltenecker , Julia Zuber , Juliano Machado , Lisa Mehr , Foivos-Filippos Tsokanos , Hanna Kuzi , Chris D Hermann , Michael Voelkl , German Monogarov , Christoph Springfeld , Victor Laurent , Bernd Engelmann , Helmut Friess , Inka Zörnig , Achim Krüger , Jeroen Krijgsveld , Olga Prokopchuk , Søren Fisker Schmidt , Maria Rohm , Stephan Herzig , Mauricio Berriel Diaz

Poly(ADP-ribose) polymerase inhibition in pancreatic cancer.

Genes, chromosomes & cancer
Avec: Hans Martin Singh , Peter Bailey , Daniel Hübschmann , Anne Katrin Berger , John P Neoptolemos , Dirk Jäger , Jens Siveke , Christoph Springfeld

Treatment stage migration and treatment sequences in patients with hepatocellular carcinoma: drawbacks and opportunities.

Journal of cancer research and clinical oncology
Avec: Cyrill Wehling , Michael T Dill , Alexander Olkus , Christoph Springfeld , De-Hua Chang , Patrick Naumann , Thomas Longerich , Clemens Kratochwil , Arianeb Mehrabi , Uta Merle , Jan Pfeiffenberger , Christian Rupp , Karl Heinz Weiss , Markus Mieth

Improving radiologic communication in oncology: a single-centre experience with structured reporting for cancer patients.

Insights into imaging
Avec: Tim Frederik Weber , Manuela Spurny , Felix Christian Hasse , Oliver Sedlaczek , Georg Martin Haag , Christoph Springfeld , Theresa Mokry , Dirk Jäger , Hans-Ulrich Kauczor , Anne Katrin Berger

Pembrolizumab and maraviroc in refractory mismatch repair proficient/microsatellite-stable metastatic colorectal cancer - The PICCASSO phase I trial.

European journal of cancer (Oxford, England : 1990)
Avec: Georg Martin Haag , Christoph Springfeld , Barbara Grün , Leonidas Apostolidis , Stefanie Zschäbitz , Mareike Dietrich , Anne-Katrin Berger , Tim Frederik Weber , Inka Zoernig , Marina Schaaf , Lisa Waberer , Daniel Wilhelm Müller , Salah-Eddin Al-Batran , Niels Halama , Dirk Jaeger

CATCH: A Prospective Precision Oncology Trial in Metastatic Breast Cancer.

JCO precision oncology
Avec: Mario Hlevnjak , Markus Schulze , Shaymaa Elgaafary , Carlo Fremd , Laura Michel , Katja Beck , Katrin Pfütze , Daniela Richter , Stephan Wolf , Peter Horak , Simon Kreutzfeldt , Constantin Pixberg , Barbara Hutter , Naveed Ishaque , Steffen Hirsch , Laura Gieldon , Albrecht Stenzinger , Christoph Springfeld , Katharina Smetanay , Julia Seitz , Athanasios Mavratzas , Benedikt Brors , Romy Kirsten , Florian Schuetz , Stefan Fröhling , Hans-Peter Sinn , Dirk Jäger , Verena Thewes , Marc Zapatka , Peter Lichter , Andreas Schneeweiss

Spatiotemporal analysis of tumour-infiltrating immune cells in biliary carcinogenesis.

British journal of cancer
Avec: Alphonse Charbel , Luca Tavernar , Thomas Albrecht , Fritz Brinkmann , Joanne Verheij , Eva Roos , Monika Nadja Vogel , Bruno Köhler , Christoph Springfeld , Alexander Brobeil , Peter Schirmacher , Stephan Singer , Arianeb Mehrabi , Stephanie Roessler , Benjamin Goeppert

Precision oncology for intrahepatic cholangiocarcinoma in clinical practice.

British journal of cancer
Avec: Aurelie Tomczak , Christoph Springfeld , Michael T Dill , De-Hua Chang , Daniel Kazdal , Ursula Wagner , Arianeb Mehrabi , Antje Brockschmidt , Tom Luedde , Patrick Naumann , Albrecht Stenzinger , Peter Schirmacher , Thomas Longerich

Prognostic Value of Red Blood Cell Distribution Width (RDW) in the Recurrence of Hepatocellular Carcinoma Following Curative Resection.

Journal of hepatocellular carcinoma
Avec: Mohammad Golriz , Ali Ramouz , Sadeq Ali-Hasan-Al-Saegh , Saeed Shafiei , Ehsan Aminizadeh , Ahmed Hammad , Markus Mieth , Christian Rupp , Christoph Springfeld , Katrin Hoffmann , Markus Büchler , Arianeb Mehrabi

Protocol of the IntenSify-Trial: An open-label phase I trial of the CYP3A inhibitor cobicistat and the cytostatics gemcitabine and nab-paclitaxel in patients with advanced stage or metastatic pancreatic ductal adenocarcinoma to evaluate the combination's pharmacokinetics, safety, and efficacy.

Clinical and translational science
Avec: Nicolas Hohmann , Martin Ronald Sprick , Moritz Pohl , Azaz Ahmed , Jürgen Burhenne , Marietta Kirchner , Lucian Le Cornet , Markus Kratzmann , Jacek Hajda , Albrecht Stenzinger , Karen Steindorf , Stefan Delorme , Heinz-Peter Schlemmer , Sabine Riethdorf , Ron van Schaik , Klaus Pantel , Jens Siveke , Thomas Seufferlein , Dirk Jäger , Walter E Haefeli , Andreas Trumpp , Christoph Springfeld

Surgical management of primary liver cancers during the COVID-19 pandemic: overcoming the dilemma with standardization.

HPB : the official journal of the International Hepato Pancreato Biliary Association
Avec: Ali Ramouz , Sanam Fakour , Marzieh Jafari , Elias Khajeh , Mohammad Golriz , Ali Majlesara , Uta Merle , Christoph Springfeld , Thomas Longerich , Markus Mieth , Arianeb Mehrabi

Carbon ion radiotherapy of hepatocellular carcinoma provides excellent local control: The prospective phase I PROMETHEUS trial.

JHEP reports : innovation in hepatology
Avec: Philipp Hoegen-Saßmannshausen , Patrick Naumann , Paula Hoffmeister-Wittmann , Semi Ben Harrabi , Katharina Seidensaal , Fabian Weykamp , Thomas Mielke , Malte Ellerbrock , Daniel Habermehl , Christoph Springfeld , Michael T Dill , Thomas Longerich , Peter Schirmacher , Arianeb Mehrabi , De-Hua Chang , Juliane Hörner-Rieber , Oliver Jäkel , Thomas Haberer , Stephanie E Combs , Jürgen Debus , Klaus Herfarth , Jakob Liermann

Réseau de co-auteurs

Arianeb Mehrabi 30 collaborations
Dirk Jäger 21 collaborations
Benjamin Goeppert 19 collaborations
Thilo Hackert 19 collaborations
Peter Schirmacher 18 collaborations
Stephanie Roessler 17 collaborations
Thomas Albrecht 15 collaborations
Christian Rupp 13 collaborations
Markus W Büchler 12 collaborations
Bruno Köhler 10 collaborations
Karl Heinz Weiss 10 collaborations
Thomas Longerich 10 collaborations
Stephan Singer 9 collaborations
John P Neoptolemos 9 collaborations
De-Hua Chang 9 collaborations
Albrecht Stenzinger 8 collaborations
Monika Nadja Vogel 8 collaborations
Markus Mieth 8 collaborations
Katrin Hoffmann 7 collaborations
Anne Katrin Berger 7 collaborations
Niels Halama 7 collaborations
Benedikt Brors 7 collaborations
Marcus Renner 6 collaborations
Ali Ramouz 6 collaborations
Stefan Fröhling 6 collaborations
Jan Pfeiffenberger 6 collaborations
Peter Bailey 6 collaborations
Oliver Strobel 5 collaborations
Elias Khajeh 5 collaborations
Mohammad Golriz 5 collaborations
Bruno C Köhler 5 collaborations
Azaz Ahmed 5 collaborations
Rosa Klotz 5 collaborations
Uta Merle 5 collaborations
Michael T Dill 5 collaborations
Patrick Naumann 5 collaborations
Alphonse Charbel 5 collaborations
Xu Zhou 5 collaborations
Kai Hu 5 collaborations
Jingyu An 5 collaborations
Teresa Peccerella 5 collaborations
None None 4 collaborations
Anita Pathil 4 collaborations
Christine Tjaden 4 collaborations
Ulrike Heger 4 collaborations
Sadeq Ali-Hasan-Al-Saegh 4 collaborations
Paula Hoffmeister-Wittmann 4 collaborations
Elena Busch 4 collaborations
Melina Rausch 4 collaborations
Sophia Köhler 4 collaborations
Nathalia Giese 4 collaborations
Leonidas Apostolidis 4 collaborations
Georg Martin Haag 4 collaborations
Michael Albrecht 4 collaborations
Fritz Brinkmann 4 collaborations
Susanne Roth 4 collaborations
Roma Kurilov 4 collaborations
Peter Horak 4 collaborations
Salah-Eddin Al-Batran 3 collaborations
Olaf Neumann 3 collaborations
Ulf Hinz 3 collaborations
Mohammed Al-Saeedi 3 collaborations
Frank Bergmann 3 collaborations
Markus K Diener 3 collaborations
Guy Ungerechts 3 collaborations
Ulla Klaiber 3 collaborations
Saeed Shafiei 3 collaborations
Pascal Probst 3 collaborations
Anna-Lena Scherr 3 collaborations
Luisa Nader 3 collaborations
Kaiyu Xu 3 collaborations
Federico Nichetti 3 collaborations
Sarah Fritzsche 3 collaborations
Eblina Kelmendi 3 collaborations
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Felix Korell 3 collaborations
Annika Kessler 3 collaborations
Jennifer Hüllein 3 collaborations
Kai Breuhahn 3 collaborations
Elena Czink 3 collaborations
Magnus von Knebel Doeberitz 3 collaborations
Matthias Kloor 3 collaborations
Inka Zörnig 3 collaborations
Stefanie Zschäbitz 3 collaborations
Cyrill Wehling 3 collaborations
Anita Pathil-Warth 3 collaborations
Nicolas Hohmann 3 collaborations
Monika N Vogel 3 collaborations
Jens Siveke 3 collaborations
Hanno Glimm 3 collaborations
Simon Kreutzfeldt 3 collaborations
Barbara Hutter 3 collaborations
Johannes Schreck 3 collaborations
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Markus Büchler 3 collaborations
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Qiangnu Zhang 2 collaborations
Anja A Kühl 2 collaborations
Nalân Utku 2 collaborations
Moritz Loeffler 2 collaborations
Christoph Berchtold 2 collaborations
Martin Schneider 2 collaborations
Birgit Hoyler 2 collaborations
Christine E Engeland 2 collaborations
Thomas Schmidt 2 collaborations
Sanam Fakour 2 collaborations
Ali Majlesara 2 collaborations
Carlos Carvalho 2 collaborations
Sofia M E Weiler 2 collaborations
Maximilian Schwab 2 collaborations
Hanna Isele 2 collaborations
Christoph E Heilig 2 collaborations
Bénédicte Lenoir 2 collaborations
Nina Wilhelm 2 collaborations
Ulrike Gärtner 2 collaborations
Rene Jackstadt 2 collaborations
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Georg M Haag 2 collaborations
Carlo Fremd 2 collaborations
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Ehsan Aminizadeh 2 collaborations
Arash Dooghaie Moghadam 2 collaborations
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Evelin Schröck 2 collaborations
Daniel H Palmer 2 collaborations
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