Local nucleosome dynamics and eviction following a double-strand break are reversible by NHEJ-mediated repair in the absence of DNA replication.


Journal

Genome research
ISSN: 1549-5469
Titre abrégé: Genome Res
Pays: United States
ID NLM: 9518021

Informations de publication

Date de publication:
05 2021
Historique:
received: 01 09 2020
accepted: 26 03 2021
pubmed: 4 4 2021
medline: 11 3 2022
entrez: 3 4 2021
Statut: ppublish

Résumé

We interrogated at nucleotide resolution the spatiotemporal order of chromatin changes that occur immediately following a site-specific double-strand break (DSB) upstream of the

Identifiants

pubmed: 33811083
pii: gr.271155.120
doi: 10.1101/gr.271155.120
pmc: PMC8092003
doi:

Substances chimiques

DNA-Binding Proteins 0
Nucleosomes 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

775-788

Subventions

Organisme : NIGMS NIH HHS
ID : R01 GM061766
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM118551
Pays : United States
Organisme : NIGMS NIH HHS
ID : R35 GM127029
Pays : United States
Organisme : NIGMS NIH HHS
ID : R35 GM127062
Pays : United States

Informations de copyright

© 2021 Tripuraneni et al.; Published by Cold Spring Harbor Laboratory Press.

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Auteurs

Vinay Tripuraneni (V)

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

Gonen Memisoglu (G)

Department of Molecular Genetics and Cell Biology, The University of Chicago, Chicago, Illinois 60637, USA.

Heather K MacAlpine (HK)

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

Trung Q Tran (TQ)

Department of Computer Science, Duke University, Durham, North Carolina 27708, USA.

Wei Zhu (W)

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

Alexander J Hartemink (AJ)

Department of Computer Science, Duke University, Durham, North Carolina 27708, USA.

James E Haber (JE)

Department of Biology and Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, Massachusetts 02454, USA.

David M MacAlpine (DM)

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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Classifications MeSH