Evolutionary and phylogenetic analyses of the barcoding region suggest geographical relationships among Blastocystis sp., ST3 in humans.
Blastocystis
Haplotype network
Nucleotide diversity
Population analysis
Subtype 3
Journal
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
ISSN: 1567-7257
Titre abrégé: Infect Genet Evol
Pays: Netherlands
ID NLM: 101084138
Informations de publication
Date de publication:
12 2021
12 2021
Historique:
received:
27
02
2021
revised:
11
11
2021
accepted:
16
11
2021
pubmed:
22
11
2021
medline:
15
1
2022
entrez:
21
11
2021
Statut:
ppublish
Résumé
Blastocystis sp., has 21 distinct subtypes of which ST3 thought to be the most prevalent subtype. This study aims to analyze the global variations of ST3. In total, 496 sequences with more than 400 nucleotides from Asia, Europe, Africa, and America were included in this study. Results show that allele 34 was the most prevalent allele in all continents. The lowest and highest allele diversity were observed in Europe and Africa, respectively. The nucleotide diversity ranged from 0.0077 in Europe to 0.02 in Africa, and haplotype diversity ranged from 0.461 in America to 0.6 in Africa. The haplotype network and Bayesian structure showed at least two major clusters including Asia and Europe-Africa-America. Tajima's D values for all continents were negative and statistically significant, indicating an excess of rare nucleotide variants. Similarly, the Fu's FS test showed negative values for all regions, indicating an excess of rare haplotypes. Pairwise F
Identifiants
pubmed: 34801757
pii: S1567-1348(21)00451-2
doi: 10.1016/j.meegid.2021.105151
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
105151Informations de copyright
Copyright © 2021 The Author(s). Published by Elsevier B.V. All rights reserved.