Genomic and Chemical Decryption of the Bacteroidetes Phylum for Its Potential to Biosynthesize Natural Products.

Bacteroidetes NRPS antifungal genomics metabolomics natural products

Journal

Microbiology spectrum
ISSN: 2165-0497
Titre abrégé: Microbiol Spectr
Pays: United States
ID NLM: 101634614

Informations de publication

Date de publication:
29 06 2022
Historique:
pubmed: 21 4 2022
medline: 2 7 2022
entrez: 20 4 2022
Statut: ppublish

Résumé

With progress in genome sequencing and data sharing, 1,000s of bacterial genomes are publicly available. Genome mining-using bioinformatics tools in terms of biosynthetic gene cluster (BGC) identification, analysis, and rating-has become a key technology to explore the capabilities for natural product (NP) biosynthesis. Comprehensively, analyzing the genetic potential of the phylum Bacteroidetes revealed

Identifiants

pubmed: 35442080
doi: 10.1128/spectrum.02479-21
pmc: PMC9248904
doi:

Substances chimiques

Biological Products 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0247921

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Auteurs

Stephan Brinkmann (S)

Fraunhofer Institute for Molecular Biology and Applied Ecologygrid.418010.c (IME), Branch for Bioresources, Giessen, Germany.

Michael Kurz (M)

Sanofi-Aventis Deutschland GmbH, Frankfurt am Main, Germany.

Maria A Patras (MA)

Fraunhofer Institute for Molecular Biology and Applied Ecologygrid.418010.c (IME), Branch for Bioresources, Giessen, Germany.

Christoph Hartwig (C)

Fraunhofer Institute for Molecular Biology and Applied Ecologygrid.418010.c (IME), Branch for Bioresources, Giessen, Germany.

Michael Marner (M)

Fraunhofer Institute for Molecular Biology and Applied Ecologygrid.418010.c (IME), Branch for Bioresources, Giessen, Germany.

Benedikt Leis (B)

Fraunhofer Institute for Molecular Biology and Applied Ecologygrid.418010.c (IME), Branch for Bioresources, Giessen, Germany.

André Billion (A)

Fraunhofer Institute for Molecular Biology and Applied Ecologygrid.418010.c (IME), Branch for Bioresources, Giessen, Germany.

Yolanda Kleiner (Y)

Fraunhofer Institute for Molecular Biology and Applied Ecologygrid.418010.c (IME), Branch for Bioresources, Giessen, Germany.

Armin Bauer (A)

Sanofi-Aventis Deutschland GmbH, Frankfurt am Main, Germany.

Luigi Toti (L)

Sanofi-Aventis Deutschland GmbH, Frankfurt am Main, Germany.

Christoph Pöverlein (C)

Sanofi-Aventis Deutschland GmbH, Frankfurt am Main, Germany.

Peter E Hammann (PE)

Evotec International GmbH, Göttingen, Germany.

Andreas Vilcinskas (A)

Fraunhofer Institute for Molecular Biology and Applied Ecologygrid.418010.c (IME), Branch for Bioresources, Giessen, Germany.
Institute for Insect Biotechnology, Justus-Liebig-University Giessen, Giessen, Germany.

Jens Glaeser (J)

Fraunhofer Institute for Molecular Biology and Applied Ecologygrid.418010.c (IME), Branch for Bioresources, Giessen, Germany.
Evotec International GmbH, Göttingen, Germany.

Marius Spohn (M)

Fraunhofer Institute for Molecular Biology and Applied Ecologygrid.418010.c (IME), Branch for Bioresources, Giessen, Germany.

Till F Schäberle (TF)

Fraunhofer Institute for Molecular Biology and Applied Ecologygrid.418010.c (IME), Branch for Bioresources, Giessen, Germany.
Institute for Insect Biotechnology, Justus-Liebig-University Giessen, Giessen, Germany.

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Classifications MeSH