Biosynthetic Pathways of Tryptophan Metabolites in

Tryptophan / metabolism Saccharomyces cerevisiae / metabolism Serotonin / metabolism 5-Hydroxytryptophan / metabolism Biosynthetic Pathways Melatonin / metabolism Tandem Mass Spectrometry Chromatography, Liquid / methods
5-hydroxytryptophan LC-MS/MS indolamines melatonin probiotic strains serotonin sustainability yeast strain

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
26 Apr 2024
Historique:
received: 29 02 2024
revised: 15 04 2024
accepted: 24 04 2024
medline: 11 5 2024
pubmed: 11 5 2024
entrez: 11 5 2024
Statut: epublish

Résumé

Tryptophan metabolites, such as 5-hydroxytryptophan (5-HTP), serotonin, and melatonin, hold significant promise as supplements for managing various mood-related disorders, including depression and insomnia. However, their chemical production via chemical synthesis and phytochemical extraction presents drawbacks, such as the generation of toxic byproducts and low yields. In this study, we explore an alternative approach utilizing

Identifiants

DOI: 10.3390/ijms25094747 PMID: 38731967
pubmed: 38731967
pii: ijms25094747
doi: 10.3390/ijms25094747
pii:
doi:

Substances chimiques

Tryptophan 8DUH1N11BX
Serotonin 333DO1RDJY
5-Hydroxytryptophan C1LJO185Q9
Melatonin JL5DK93RCL

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Hsin-Chieh Kung (HC)

Institute of Environmental Toxin and Emerging Contaminant, Cheng Shiu University, Kaohsiung 83347, Taiwan.

Ngoc-Han Bui (NH)

Institute of Environmental Toxin and Emerging Contaminant, Cheng Shiu University, Kaohsiung 83347, Taiwan.

Bo-Wun Huang (BW)

Department of Mechanical and Institute of Mechatronic Engineering, Cheng Shiu University, Kaohsiung 83347, Taiwan.
ORCID: 0000-0002-6026-5110

Nicholas Kiprotich Cheruiyot (NK)

Institute of Environmental Toxin and Emerging Contaminant, Cheng Shiu University, Kaohsiung 83347, Taiwan.
Center for Environmental Toxin and Emerging-Contaminant Research, Cheng Shiu University, Kaohsiung 83347, Taiwan.
ORCID: 0000-0003-2746-107X

Guo-Ping Chang-Chien (GP)

Institute of Environmental Toxin and Emerging Contaminant, Cheng Shiu University, Kaohsiung 83347, Taiwan.
Center for Environmental Toxin and Emerging-Contaminant Research, Cheng Shiu University, Kaohsiung 83347, Taiwan.

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Acides aminés › Acides aminés essentiels › Tryptophane › Biosynthetic Pathways of Tryptophan Metabolites in
questionsmedicales.fr › Eucaryotes › Champignons › Levures › Saccharomyces › Saccharomyces cerevisiae › Biosynthetic Pathways of Tryptophan Metabolites in
questionsmedicales.fr › Facteurs biologiques › Médiateurs de l'inflammation › Autacoïdes › Sérotonine › Biosynthetic Pathways of Tryptophan Metabolites in
questionsmedicales.fr › Acides aminés, peptides et protéines › Acides aminés › Acides aminés cycliques › Acides aminés aromatiques › 5-Hydroxytryptophane › Biosynthetic Pathways of Tryptophan Metabolites in
questionsmedicales.fr › Métabolisme › Voies et réseaux métaboliques › Voies de biosynthèse › Biosynthetic Pathways of Tryptophan Metabolites in
questionsmedicales.fr › Mélatonine › Biosynthetic Pathways of Tryptophan Metabolites in
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Spectrométrie de masse › Spectrométrie de masse en tandem › Biosynthetic Pathways of Tryptophan Metabolites in
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Chromatographie › Chromatographie en phase liquide › Biosynthetic Pathways of Tryptophan Metabolites in