C Cremolini

Affiliations

Department of Translational Research and New Technologies in Medicine and Surgery, Unit of Medical Oncology, Azienda Ospedaliero-Universitaria Pisana, University of Pisa, Pisa. Electronic address: chiaracremolini@gmail.com.

Publications (100)

Prognostic impact of ATM mutations in patients with metastatic colorectal cancer.

Scientific reports

Avec: Giovanni Randon , Giovanni Fucà , Daniele Rossini , Alessandra Raimondi , Filippo Pagani , Federica Perrone , Elena Tamborini , Adele Busico , Giorgia Peverelli , Federica Morano , Monica Niger , Maria Antista , Salvatore Corallo , Serena Saggio , Beatrice Borelli , Gemma Zucchelli , Massimo Milione , Giancarlo Pruneri , Maria Di Bartolomeo , Alfredo Falcone , Filippo de Braud , Chiara Cremolini , Filippo Pietrantonio

DPYD6 plays an important role in fluoropyrimidine toxicity in addition to DPYD2A and c.2846A>T: a comprehensive analysis in 1254 patients.

The pharmacogenomics journal

Avec: Marzia Del Re , Saverio Cinieri , Angela Michelucci , Stefano Salvadori , Fotios Loupakis , Marta Schirripa , Chiara Cremolini , Stefania Crucitta , Cecilia Barbara , Angelo Di Leo , Tiziana Pia Latiano , Filippo Pietrantonio , Samantha Di Donato , Paolo Simi , Alessandro Passardi , Filippo De Braud , Giuseppe Altavilla , Claudio Zamagni , Roberto Bordonaro , Alfredo Butera , Evaristo Maiello , Carmine Pinto , Alfredo Falcone , Valentina Mazzotti , Riccardo Morganti , Romano Danesi

Phase II randomised study of maintenance treatment with bevacizumab or bevacizumab plus metronomic chemotherapy after first-line induction with FOLFOXIRI plus Bevacizumab for metastatic colorectal cancer patients: the MOMA trial.

European journal of cancer (Oxford, England : 1990)

Avec: Chiara Cremolini , Federica Marmorino , Francesca Bergamo , Giuseppe Aprile , Lisa Salvatore , Gianluca Masi , Emanuela Dell'Aquila , Carlotta Antoniotti , Sabina Murgioni , Giacomo Allegrini , Beatrice Borelli , Donatello Gemma , Mariaelena Casagrande , Cristina Granetto , Sara Delfanti , Samantha Di Donato , Marta Schirripa , Elisa Sensi , Giuseppe Tonini , Sara Lonardi , Gabriella Fontanini , Luca Boni , Alfredo Falcone

Early modifications of circulating microRNAs levels in metastatic colorectal cancer patients treated with regorafenib.

The pharmacogenomics journal

Avec: Marta Schirripa , Beatrice Borelli , Romina D'Aurizio , Simone Lubrano , Chiara Cremolini , Gemma Zucchelli , Carlotta Antoniotti , Federica Marmorino , Alessandra Anna Prete , Sabina Murgioni , Francesca Bergamo , Vittorina Zagonel , Andrea Tuccoli , Andrea Marranci , Milena Rizzo , Lorena Tedeschi , Letizia Magnoni , Alfredo Falcone , Fotios Loupakis , Laura Poliseno

Impact of age and gender on the safety and efficacy of chemotherapy plus bevacizumab in metastatic colorectal cancer: a pooled analysis of TRIBE and TRIBE2 studies.

Annals of oncology : official journal of the European Society for Medical Oncology

Avec: F Marmorino , D Rossini , S Lonardi , R Moretto , G Zucchelli , G Aprile , E Dell'Aquila , M Ratti , F Bergamo , G Masi , F Urbano , M Ronzoni , M Libertini , B Borelli , G Randon , A Buonadonna , G Allegrini , N Pella , V Ricci , A Boccaccino , T P Latiano , S Cordio , A Passardi , E Tamburini , L Boni , A Falcone , C Cremolini

Quantitative evidence for early metastatic seeding in colorectal cancer.

Nature genetics

Avec: Zheng Hu , Jie Ding , Zhicheng Ma , Ruping Sun , Jose A Seoane , J Scott Shaffer , Carlos J Suarez , Anna S Berghoff , Chiara Cremolini , Alfredo Falcone , Fotios Loupakis , Peter Birner , Matthias Preusser , Heinz-Josef Lenz , Christina Curtis

Long Term Survival With Regorafenib: REALITY (Real Life in Italy) Trial - A GISCAD Study.

Clinical colorectal cancer

Avec: Eleonora Lai , Marco Puzzoni , Pina Ziranu , Chiara Cremolini , Sara Lonardi , Maria Banzi , Stefano Mariani , Nicole Liscia , Saverio Cinieri , Manuela Dettori , Manlio Mencoboni , Floriana Nappo , Giulia Piacentini , Roberto Labianca , Gemma Zucchelli , Alessandra Boccaccino , Veronica Conca , Valeria Pusceddu , Alberto Zaniboni , Mario Scartozzi , Auteur inconnu

Nomogram to predict the outcomes of patients with microsatellite instability-high metastatic colorectal cancer receiving immune checkpoint inhibitors.

Journal for immunotherapy of cancer

Avec: Filippo Pietrantonio , Sara Lonardi , Francesca Corti , Gabriele Infante , Maria Elena Elez , Marwan Fakih , Priya Jayachandran , Aakash Tushar Shah , Massimiliano Salati , Elisabetta Fenocchio , Lisa Salvatore , Giuseppe Curigliano , Chiara Cremolini , Margherita Ambrosini , Javier Ros , Rossana Intini , Floriana Nappo , Silvia Damian , Federica Morano , Giovanni Fucà , Michael Overman , Rosalba Miceli

Prognostic impact of early tumor shrinkage and depth of response in patients with microsatellite instability-high metastatic colorectal cancer receiving immune checkpoint inhibitors.

Journal for immunotherapy of cancer

Avec: Giovanni Fucà , Francesca Corti , Margherita Ambrosini , Rossana Intini , Massimiliano Salati , Elisabetta Fenocchio , Paolo Manca , Chiara Manai , Francesca Daniel , Alessandra Raimondi , Federica Morano , Salvatore Corallo , Michele Prisciandaro , Andrea Spallanzani , Virginia Quarà , Carmen Belli , Marta Vaiani , Giuseppe Curigliano , Chiara Cremolini , Filippo De Braud , Maria Di Bartolomeo , Vittorina Zagonel , Sara Lonardi , Filippo Pietrantonio

Polymorphisms within Immune Regulatory Pathways Predict Cetuximab Efficacy and Survival in Metastatic Colorectal Cancer Patients.

Cancers

Avec: Nico B Volz , Diana L Hanna , Sebastian Stintzing , Wu Zhang , Dongyun Yang , Shu Cao , Yan Ning , Satoshi Matsusaka , Yu Sunakawa , Martin D Berger , Chiara Cremolini , Fotios Loupakis , Alfredo Falcone , Heinz-Josef Lenz

Management of patients with early-stage colon cancer: guidelines of the Italian Medical Oncology Association.

ESMO open

Avec: Lisa Salvatore , Marco Imperatori , Ermenegildo Arnoldi , Carlo Carnaghi , Stefano Cordio , Maurizio Cosimelli , Chiara Cremolini , Evaristo Maiello , Erika Martinelli , Nicola Normanno , Stefania Sciallero , Renato Cannizzaro , Daniela Musio , Michela Cinquini , Ivan Moschetti , Veronica Andrea Fittipaldo , Giuseppe Aprile , Giordano D Beretta

FOLFOXIRI-Bevacizumab or FOLFOX-Panitumumab in Patients with Left-Sided RAS/BRAF Wild-Type Metastatic Colorectal Cancer: A Propensity Score-Based Analysis.

The oncologist

Avec: Filippo Pietrantonio , Giovanni Fucà , Daniele Rossini , Hans-Joachim Schmoll , Johanna C Bendell , Federica Morano , Carlotta Antoniotti , Salvatore Corallo , Beatrice Borelli , Alessandra Raimondi , Federica Marmorino , Monica Niger , Alessandra Boccaccino , Gianluca Masi , Sara Lonardi , Luca Boni , Filippo de Braud , Maria Di Bartolomeo , Alfredo Falcone , Chiara Cremolini

Treatments after first progression in metastatic colorectal cancer. A literature review and evidence-based algorithm.

Cancer treatment reviews

Avec: Carlotta Antoniotti , Roberto Moretto , Daniele Rossini , Gianluca Masi , Alfredo Falcone , Chiara Cremolini

RNA-Binding Protein Polymorphisms as Novel Biomarkers to Predict Outcomes of Metastatic Colorectal Cancer: A Meta-analysis from TRIBE, FIRE-3, and MAVERICC.

Molecular cancer therapeutics

Avec: Hiroyuki Arai , Shu Cao , Francesca Battaglin , Jingyuan Wang , Natsuko Kawanishi , Ryuma Tokunaga , Fotios Loupakis , Sebastian Stintzing , Shivani Soni , Wu Zhang , Christoph Mancao , Bodour Salhia , Shannon M Mumenthaler , Chiara Cremolini , Volker Heinemann , Alfredo Falcone , Joshua Millstein , Heinz-Josef Lenz

TremelImumab and Durvalumab Combination for the Non-OperatIve Management (NOM) of Microsatellite InstabiliTY (MSI)-High Resectable Gastric or Gastroesophageal Junction Cancer: The Multicentre, Single-Arm, Multi-Cohort, Phase II INFINITY Study.

Cancers

Avec: Alessandra Raimondi , Federica Palermo , Michele Prisciandaro , Massimo Aglietta , Lorenzo Antonuzzo , Giuseppe Aprile , Rossana Berardi , Giovanni G Cardellino , Giovanni De Manzoni , Ferdinando De Vita , Massimo Di Maio , Lorenzo Fornaro , Giovanni L Frassineti , Cristina Granetto , Francesco Iachetta , Sara Lonardi , Roberto Murialdo , Elena Ongaro , Francesca Pucci , Margherita Ratti , Nicola Silvestris , Valeria Smiroldo , Andrea Spallanzani , Antonia Strippoli , Stefano Tamberi , Emiliano Tamburini , Alberto Zaniboni , Maria Di Bartolomeo , Chiara Cremolini , Carlo Sposito , Vincenzo Mazzaferro , Filippo Pietrantonio

Rationale and Study Design of the PARERE Trial: Randomized phase II Study of Panitumumab Re-Treatment Followed by Regorafenib Versus the Reverse Sequence in RAS and BRAF Wild-Type Chemo-Refractory Metastatic Colorectal Cancer Patients.

Clinical colorectal cancer

Avec: Roberto Moretto , Daniele Rossini , Iolanda Capone , Alessandra Boccaccino , Federica Perrone , Elena Tamborini , Gianluca Masi , Carlotta Antoniotti , Federica Marmorino , Veronica Conca , Beatrice Borelli , Angelo Martignetti , Irene Pecora , Francesca Simionato , Samanta Cupini , Margherita Ambrosini , Paolo Manca , Filippo Pietrantonio , Alfredo Falcone , Chiara Cremolini

Tumour mutational burden, microsatellite instability, and actionable alterations in metastatic colorectal cancer: Next-generation sequencing results of TRIBE2 study.

European journal of cancer (Oxford, England : 1990)

Avec: Carlotta Antoniotti , W Michael Korn , Federica Marmorino , Daniele Rossini , Sara Lonardi , Gianluca Masi , Giovanni Randon , Veronica Conca , Alessandra Boccaccino , Gianluca Tomasello , Alessandro Passardi , Jeff Swensen , Clara Ugolini , Matthew Oberley , Emiliano Tamburini , Mariaelena Casagrande , Valeriy Domenyuk , Gabriella Fontanini , Mirella Giordano , Jim Abraham , David Spetzler , Alfredo Falcone , Heinz-Josef Lenz , Chiara Cremolini

CEA increase as a marker of disease progression after first-line induction therapy in metastatic colorectal cancer patients. A pooled analysis of TRIBE and TRIBE2 studies.

British journal of cancer

Avec: Roberto Moretto , Daniele Rossini , Veronica Conca , Sara Lonardi , Cosimo Rasola , Carlotta Antoniotti , Daniele Santini , Federica Marmorino , Gianluca Tomasello , Beatrice Borelli , Salvatore Caponnetto , Gemma Zucchelli , Alberto Zaniboni , Margherita Ambrosini , Angela Buonadonna , Laura Fanchini , Samanta Cupini , Gianluca Masi , Alfredo Falcone , Chiara Cremolini

FOLFOXIRI and bevacizumab in patients with early-onset metastatic colorectal cancer. A pooled analysis of TRIBE and TRIBE2 studies.

European journal of cancer (Oxford, England : 1990)

Avec: Carlotta Antoniotti , Marco M Germani , Daniele Rossini , Sara Lonardi , Filippo Pietrantonio , Daniele Santini , Federica Marmorino , Giacomo Allegrini , Francesca Daniel , Alessandra Raimondi , Beatrice Borelli , Alberto Zaniboni , Veronica Conca , Jim Abraham , David Spetzler , Evaristo Maiello , Alessandra Boccaccino , Alessandro Passardi , Mirella Giordano , Emiliano Tamburini , Michael W Korn , Gianluca Masi , Chiara Cremolini

Benefit from upfront FOLFOXIRI and bevacizumab in BRAFV600E-mutated metastatic colorectal cancer patients: does primary tumour location matter?

British journal of cancer

Avec: Roberto Moretto , Andrew Elliott , Daniele Rossini , Rossana Intini , Veronica Conca , Filippo Pietrantonio , Andrea Sartore-Bianchi , Carlotta Antoniotti , Cosimo Rasola , Mario Scartozzi , Massimiliano Salati , Nicoletta Pella , Maria Alessandra Calegari , Martina Carullo , Francesca Corti , Gianluca Mauri , Matteo Fassan , Gianluca Masi , Pavel Brodskiy , Heinz-Josef Lenz , Anthony Shields , Sara Lonardi , Michael Korn , Chiara Cremolini

Upfront Modified Fluorouracil, Leucovorin, Oxaliplatin, and Irinotecan Plus Panitumumab Versus Fluorouracil, Leucovorin, and Oxaliplatin Plus Panitumumab for Patients With

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Avec: Daniele Rossini , Carlotta Antoniotti , Sara Lonardi , Filippo Pietrantonio , Roberto Moretto , Lorenzo Antonuzzo , Alessandra Boccaccino , Federica Morano , Marco Brugia , Carmelo Pozzo , Federica Marmorino , Francesca Bergamo , Emiliano Tamburini , Alessandro Passardi , Giovanni Randon , Sabina Murgioni , Beatrice Borelli , Angela Buonadonna , Mirella Giordano , Gabriella Fontanini , Veronica Conca , Vincenzo Formica , Massimo Aglietta , Roberto Bordonaro , Giuseppe Aprile , Gianluca Masi , Luca Boni , Chiara Cremolini

Steroid treatment in the management of destructive thyrotoxicosis induced by PD1 blockade.

European thyroid journal

Avec: Alessandro Brancatella , Laura Pierotti , Nicola Viola , Isabella Lupi , Lucia Montanelli , Chiara Cremolini , Paolo Piaggi , Antonio Chella , Andrea Antonuzzo , Daniele Sgrò , Lucia Antonangeli , Chiara Sardella , Sandra Brogioni , Claudio Marcocci , Ferruccio Santini , Francesco Latrofa

Safety and Activity of PolyPEPI1018 Combined with Maintenance Therapy in Metastatic Colorectal Cancer: an Open-Label, Multicenter, Phase Ib Study.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Joleen M Hubbard , Enikő R Tőke , Roberto Moretto , Rondell P Graham , Hagop Youssoufian , Orsolya Lőrincz , Levente Molnár , Zsolt Csiszovszki , Jessica L Mitchell , Jaclynn Wessling , József Tóth , Chiara Cremolini

Dissecting tumor lymphocyte infiltration to predict benefit from immune-checkpoint inhibitors in metastatic colorectal cancer: lessons from the AtezoT RIBE study.

Journal for immunotherapy of cancer

Avec: Roberto Moretto , Daniele Rossini , Aurélie Catteau , Carlotta Antoniotti , Mirella Giordano , Alessandra Boccaccino , Clara Ugolini , Agnese Proietti , Veronica Conca , Alboukadel Kassambara , Filippo Pietrantonio , Lisa Salvatore , Sara Lonardi , Stefano Tamberi , Emiliano Tamburini , Anello Marcello Poma , Jacques Fieschi , Gabriella Fontanini , Gianluca Masi , Jérôme Galon , Chiara Cremolini

Negative hyper-selection of patients with HER2-positive and RAS wild-type metastatic colorectal cancer receiving dual HER2 blockade: the PRESSING-HER2 study.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Giovanni Randon , Yoshiaki Nakamura , Rona Yaeger , Sara Lonardi , Chiara Cremolini , Elena Élez , Federico Nichetti , Filippo Ghelardi , Vincenzo Nasca , Francesca Bergamo , Veronica Conca , Javier Ros , Hideaki Bando , Giulia Maddalena , Simone Oldani , Michele Prisciandaro , Alessandra Raimondi , Alexa B Schrock , Luca Agnelli , Henry Walch , Takayuki Yoshino , Filippo Pietrantonio

A Misleading Case of NTRK-Rearranged Papillary Thyroid Carcinoma.

The oncologist

Avec: Marco Maria Germani , Chiara Boccaccio , Antonio Matrone , Eleonora Molinaro , Greta Alì , Mirella Giordano , Rossella Elisei , Gabriella Fontanini , Chiara Cremolini

Reinduction of an Anti-EGFR-based First-line Regimen in Patients with RAS Wild-type Metastatic Colorectal Cancer Enrolled in the Valentino Study.

The oncologist

Avec: Giovanni Fucà , Alessandra Raimondi , Michele Prisciandaro , Sara Lonardi , Chiara Cremolini , Margherita Ratti , Matteo Clavarezza , Roberto Murialdo , Andrea Sartore-Bianchi , Valeria Smiroldo , Rosa Berenato , Patrizia Racca , Francesca Bergamo , Salvatore Corallo , Maria Di Bartolomeo , Filippo de Braud , Federica Morano , Filippo Pietrantonio

Surgery combined with intra-operative microwaves ablation for the management of colorectal cancer liver metastasis: A case-matched analysis and evaluation of recurrences.

Frontiers in oncology

Avec: Simone Guadagni , Federica Marmorino , Niccolò Furbetta , Martina Carullo , Desirée Gianardi , Matteo Palmeri , Gregorio Di Franco , Annalisa Comandatore , Roberto Moretto , Elisa Cecilia , Giovanni Dima , Gianluca Masi , Chiara Cremolini , Giulio Di Candio , Luca Morelli

Association of immune-related adverse events with the outcomes of immune checkpoint inhibitors in patients with dMMR/MSI-H metastatic colorectal cancer.

Journal for immunotherapy of cancer

Avec: Vincenzo Nasca , Francesco Barretta , Francesca Corti , Sara Lonardi , Monica Niger , Maria Elena Elez , Marwan Fakih , Priya Jayachandran , Aakash Tushar Shah , Massimiliano Salati , Elisabetta Fenocchio , Lisa Salvatore , Chiara Cremolini , Javier Ros , Margherita Ambrosini , Giacomo Mazzoli , Rossana Intini , Michael J Overman , Rosalba Miceli , Filippo Pietrantonio

Immune-related pan-cancer gene expression signatures of patient survival revealed by NanoString-based analyses.

PloS one

Avec: Alberto D'Angelo , Huseyin Kilili , Robert Chapman , Daniele Generali , Ingeborg Tinhofer , Stefano Luminari , Benedetta Donati , Alessia Ciarrocchi , Riccardo Giannini , Roberto Moretto , Chiara Cremolini , Filippo Pietrantonio , Navid Sobhani , Debora Bonazza , Robert Prins , Seung Geun Song , Yoon Kyung Jeon , Giuseppina Pisignano , Mattia Cinelli , Stefan Bagby , Araxi O Urrutia

Sotorasib plus Panitumumab in Refractory Colorectal Cancer with Mutated

The New England journal of medicine

Avec: Marwan G Fakih , Lisa Salvatore , Taito Esaki , Dominik P Modest , David P Lopez-Bravo , Julien Taieb , Michalis V Karamouzis , Erika Ruiz-Garcia , Tae-Won Kim , Yasutoshi Kuboki , Fausto Meriggi , David Cunningham , Kun-Huei Yeh , Emily Chan , Joseph Chao , Yaneth Saportas , Qui Tran , Chiara Cremolini , Filippo Pietrantonio

Hepatectomy versus systemic therapy for liver-limited BRAF V600E-mutated colorectal liver metastases: multicentre retrospective study.

The British journal of surgery

Avec: Georgios Antonios Margonis , Jaeyun Jane Wang , Thomas Boerner , Roberto Moretto , Stefan Buettner , Nikolaos Andreatos , Johan Gagnière , Doris Wagner , Inger Marie Løes , Francesca Bergamo , Filippo Pietrantonio , Mario Scartozzi , Andrea Spallanzani , Bruno Vincenzi , Efstathios Antoniou , Emmanouil Pikoulis , Andrea Sartore-Bianchi , Georgios Stasinos , Kazunari Sasaki , Timothy M Pawlik , Armando Orlandi , Nicoletta Pella , Fabian Fitschek , Klaus Kaczirek , Aurélien Dupré , Ioannis Pozios , Katharina Beyer , Peter Kornprat , Federico N Aucejo , Richard Burkhart , Matthew J Weiss , Per Eystein Lønning , George Poultsides , Chiara Cremolini , Martin E Kreis , Michael D'Angelica

Author Correction: The landscape of d16HER2 splice variant expression across HER2-positive cancers.

Scientific reports

Avec: Chiara Costanza Volpi , Filippo Pietrantonio , Annunziata Gloghini , Giovanni Fucà , Silvia Giordano , Simona Corso , Giancarlo Pruneri , Maria Antista , Chiara Cremolini , Elena Fasano , Serena Saggio , Simona Faraci , Maria Di Bartolomeo , Filippo de Braud , Massimo Di Nicola , Elda Tagliabue , Serenella Maria Pupa , Lorenzo Castagnoli

Prognostic impact of immune-microenvironment in colorectal liver metastases resected after triplets plus a biologic agent: A pooled analysis of five prospective trials.

European journal of cancer (Oxford, England : 1990)

Avec: Roberto Moretto , Salvatore Corallo , Antonino Belfiore , Daniele Rossini , Alessandra Boccaccino , Sara Lonardi , Giovanni Centonze , Federica Morano , Marco Maria Germani , Fotios Loupakis , Luca Morelli , Lucio Urbani , Silvia Brich , Federica Marmorino , Michele Prisciandaro , Giuseppe Aprile , Matteo Fassan , Umberto Cillo , Laura Cattaneo , Gabriella Fontanini , Filippo De Braud , Alfredo Falcone , Massimo Milione , Filippo Pietrantonio , Chiara Cremolini

Systemic Treatment of Patients With Gastrointestinal Cancers During the COVID-19 Outbreak: COVID-19-adapted Recommendations of the National Cancer Institute of Milan.

Clinical colorectal cancer

Avec: Filippo Pietrantonio , Federica Morano , Monica Niger , Salvatore Corallo , Maria Antista , Alessandra Raimondi , Michele Prisciandaro , Filippo Pagani , Natalie Prinzi , Federico Nichetti , Giovanni Randon , Martina Torchio , Francesca Corti , Margherita Ambrosini , Federica Palermo , Michele Palazzo , Lavinia Biamonte , Marco Platania , Carlo Sposito , Maurizio Cosimelli , Vincenzo Mazzaferro , Sara Pusceddu , Chiara Cremolini , Filippo de Braud , Maria Di Bartolomeo

A polymorphism within the R-spondin 2 gene predicts outcome in metastatic colorectal cancer patients treated with FOLFIRI/bevacizumab: data from FIRE-3 and TRIBE trials.

European journal of cancer (Oxford, England : 1990)

Avec: Martin D Berger , Yan Ning , Sebastian Stintzing , Volker Heinemann , Shu Cao , Wu Zhang , Dongyun Yang , Yuji Miyamoto , Mitsukuni Suenaga , Marta Schirripa , Diana L Hanna , Shivani Soni , Alberto Puccini , Ryuma Tokunaga , Madiha Naseem , Francesca Battaglin , Chiara Cremolini , Alfredo Falcone , Fotios Loupakis , Heinz-Josef Lenz

Individual Patient Data Meta-Analysis of FOLFOXIRI Plus Bevacizumab Versus Doublets Plus Bevacizumab as Initial Therapy of Unresectable Metastatic Colorectal Cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Avec: Chiara Cremolini , Carlotta Antoniotti , Alexander Stein , Johanna Bendell , Thomas Gruenberger , Daniele Rossini , Gianluca Masi , Elena Ongaro , Herbert Hurwitz , Alfredo Falcone , Hans-Joachim Schmoll , Massimo Di Maio

Anti-EGFR Therapy in Metastatic Small Bowel Adenocarcinoma: Myth or Reality?

Clinical Medicine Insights. Oncology

Avec: Emanuela Dell'Aquila , Tea Zeppola , Marco Stellato , Francesco Pantano , Mario Scartozzi , Cristina Madaudo , Filippo Pietrantonio , Chiara Cremolini , Giuseppe Aprile , Bruno Vincenzi , Roberto Moretto , Marco Puzzoni , Silvio Ken Garattini , Riccardo Lobefaro , Giuseppe Tonini , Daniele Santini

CK7 and consensus molecular subtypes as major prognosticators in

British journal of cancer

Avec: Fotios Loupakis , Paola Biason , Alessandra Anna Prete , Chiara Cremolini , Filippo Pietrantonio , Nicoletta Pella , Emanuela Dell'Aquila , Elisa Sperti , Clizia Zichi , Rossana Intini , Vincenzo Dadduzio , Marta Schirripa , Francesca Bergamo , Carlotta Antoniotti , Federica Morano , Francesco Cortiula , Giovanna De Maglio , Lorenza Rimassa , Valeria Smiroldo , Lorenzo Calvetti , Giuseppe Aprile , Lisa Salvatore , Daniele Santini , Giada Munari , Roberta Salmaso , Vincenza Guzzardo , Claudia Mescoli , Sara Lonardi , Massimo Rugge , Vittorina Zagonel , Massimo Di Maio , Matteo Fassan

Is a pharmacogenomic panel useful to estimate the risk of oxaliplatin-related neurotoxicity in colorectal cancer patients?

The pharmacogenomics journal

Avec: Federico Nichetti , Felicia Stefania Falvella , Rosalba Miceli , Stefania Cheli , Raffaella Gaetano , Giovanni Fucà , Gabriele Infante , Antonia Martinetti , Carlotta Antoniotti , Alfredo Falcone , Maria Di Bartolomeo , Chiara Cremolini , Filippo de Braud , Filippo Pietrantonio

The landscape of d16HER2 splice variant expression across HER2-positive cancers.

Scientific reports

Metronomic Capecitabine With Cyclophosphamide Regimen in Unresectable or Relapsed Pseudomyxoma Peritonei.

Clinical colorectal cancer

Avec: Alessandra Raimondi , Salvatore Corallo , Monica Niger , Maria Antista , Giovanni Randon , Federica Morano , Massimo Milione , Shigeki Kusamura , Dario Baratti , Marcello Guaglio , Chiara Cremolini , Federica Marmorino , Maria Di Bartolomeo , Marcello Deraco , Filippo De Braud , Filippo Pietrantonio

Class 1, 2, and 3

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Marta Schirripa , Paola Biason , Sara Lonardi , Nicoletta Pella , Maria Simona Pino , Federica Urbano , Carlotta Antoniotti , Chiara Cremolini , Salvatore Corallo , Filippo Pietrantonio , Fabio Gelsomino , Stefano Cascinu , Armando Orlandi , Giada Munari , Umberto Malapelle , Serena Saggio , Gabriella Fontanini , Massimo Rugge , Claudia Mescoli , Stefano Lazzi , Luca Reggiani Bonetti , Giovanni Lanza , Angelo Paolo Dei Tos , Giovanna De Maglio , Maurizio Martini , Francesca Bergamo , Vittorina Zagonel , Fotios Loupakis , Matteo Fassan

Pharmacological effects of the simultaneous and sequential combinations of trifluridine/tipiracil (TAS-102) and 5-fluorouracil in fluoropyrimidine-sensitive colon cancer cells.

Investigational new drugs

Avec: Paola Orlandi , Daniela Gentile , Marta Banchi , Federico Cucchiara , Teresa Di Desidero , Chiara Cremolini , Roberto Moretto , Alfredo Falcone , Guido Bocci

Robotic-assisted surgery for colorectal liver metastasis: A single-centre experience.

Journal of minimal access surgery

Avec: Simone Guadagni , Niccolò Furbetta , Gregorio Di Franco , Matteo Palmeri , Desirée Gianardi , Matteo Bianchini , Martina Guadagnucci , Luca Pollina , Gianluca Masi , Chiara Cremolini , Alfredo Falcone , Franco Mosca , Giulio Di Candio , Luca Morelli

KRAS and BRAF Mutations in Stage II and III Colon Cancer: A Systematic Review and Meta-Analysis.

Journal of the National Cancer Institute

Avec: Vincenzo Formica , Francesco Sera , Chiara Cremolini , Silvia Riondino , Cristina Morelli , Hendrik-Tobias Arkenau , Mario Roselli

Immune Profiling of Deficient Mismatch Repair Colorectal Cancer Tumor Microenvironment Reveals Different Levels of Immune System Activation.

The Journal of molecular diagnostics : JMD

Avec: Riccardo Giannini , Gemma Zucchelli , Mirella Giordano , Clara Ugolini , Roberto Moretto , Katarzyna Ambryszewska , Michele Leonardi , Elisa Sensi , Federica Morano , Filippo Pietrantonio , Chiara Cremolini , Alfredo Falcone , Gabriella Fontanini

Random survival forests identify pathways with polymorphisms predictive of survival in KRAS mutant and KRAS wild-type metastatic colorectal cancer patients.

Scientific reports

Avec: Madiha Naseem , Shu Cao , Dongyun Yang , Joshua Millstein , Alberto Puccini , Fotios Loupakis , Sebastian Stintzing , Chiara Cremolini , Ryuma Tokunaga , Francesca Battaglin , Shivani Soni , Martin D Berger , Afsaneh Barzi , Wu Zhang , Alfredo Falcone , Volker Heinemann , Heinz-Josef Lenz

Encorafenib plus cetuximab treatment in BRAF V600E-mutated metastatic colorectal cancer patients pre-treated with an anti-EGFR: An AGEO-GONO case series.

European journal of cancer (Oxford, England : 1990)

Avec: Emilie Hafliger , Alessandra Boccaccino , Alexandra Lapeyre-Prost , Audrey Perret , Claire Gallois , Maria Antista , Lorenzo Pilla , Thierry Lecomte , Mario Scartozzi , Emilie Soularue , Lisa Salvatore , Vincent Bourgeois , Massimiliano Salati , David Tougeron , Ludovic Evesque , Jean-Nicolas Vaillant , Reem El-Khoury , Sara Lonardi , Chiara Cremolini , Julien Taieb

Considerations in the management of younger patients with colorectal cancer.

Clinical advances in hematology & oncology : H&O

Avec: Joleen M Hubbard , Cathy Eng , Chiara Cremolini , John L Marshall

Efficacy of immune checkpoint inhibitors for metastatic colorectal cancer with microsatellite instability in second or latter line using synthetic control arms: A non-randomised evaluation.

European journal of cancer (Oxford, England : 1990)

Avec: Romain Cohen , Morteza Raeisi , Benoist Chibaudel , Takayuki Yoshino , Qian Shi , John R Zalcberg , Richard Adams , Chiara Cremolini , Axel Grothey , Robert J Mayer , Eric Van Cutsem , Josep Tabernero , Hideaki Bando , Toshihiro Misumi , Michael J Overman , Thierry André , Aimery de Gramont

Primary Tumor Resection in Synchronous Metastatic Colorectal Cancer Patients Treated with Upfront Chemotherapy plus Bevacizumab: A Pooled Analysis of TRIBE and TRIBE2 Studies.

Cancers

Avec: Valentina Fanotto , Daniele Rossini , Mariaelena Casagrande , Francesca Bergamo , Andrea Spagnoletti , Daniele Santini , Carlotta Antoniotti , Samanta Cupini , Francesca Daniel , Vincenzo Nasca , Guglielmo Vetere , Alberto Zaniboni , Beatrice Borelli , Martina Carullo , Veronica Conca , Alessandro Passardi , Emiliano Tamburini , Gianluca Masi , Nicoletta Pella , Chiara Cremolini

Pattern of recurrence and survival after D2 right colectomy for cancer: is there place for a routine more extended lymphadenectomy?

Updates in surgery

Avec: Matteo Palmeri , Andrea Peri , Valentina Pucci , Niccolò Furbetta , Virginia Gallo , Gregorio Di Franco , Anna Pagani , Chiara Dauccia , Camilla Farè , Desirée Gianardi , Simone Guadagni , Matteo Bianchini , Annalisa Comandatore , Gianluca Masi , Chiara Cremolini , Beatrice Borelli , Luca Emanuele Pollina , Giulio Di Candio , Andrea Pietrabissa , Luca Morelli

Real-world first-line treatment of patients with BRAF

ESMO open

Avec: E Martinelli , C Cremolini , T Mazard , J Vidal , I Virchow , D Tougeron , P-J Cuyle , B Chibaudel , S Kim , I Ghanem , B Asselain , C Castagné , A Zkik , S Khan , D Arnold

RNF43 mutations predict response to anti-BRAF/EGFR combinatory therapies in BRAF

Nature medicine

Avec: Elena Elez , Javier Ros , Jose Fernández , Guillermo Villacampa , Ana Belén Moreno-Cárdenas , Carlota Arenillas , Kinga Bernatowicz , Raquel Comas , Shanshan Li , David Philip Kodack , Roberta Fasani , Ariadna Garcia , Javier Gonzalo-Ruiz , Alejandro Piris-Gimenez , Paolo Nuciforo , Grainne Kerr , Rossana Intini , Aldo Montagna , Marco Maria Germani , Giovanni Randon , Ana Vivancos , Ron Smits , Diana Graus , Raquel Perez-Lopez , Chiara Cremolini , Sara Lonardi , Filippo Pietrantonio , Rodrigo Dienstmann , Josep Tabernero , Rodrigo A Toledo

Trop-2 and Nectin-4 immunohistochemical expression in metastatic colorectal cancer: searching for the right population for drugs' development.

British journal of cancer

Avec: Roberto Moretto , Marco Maria Germani , Mirella Giordano , Veronica Conca , Agnese Proietti , Cristina Niccoli , Filippo Pietrantonio , Sara Lonardi , Emiliano Tamburini , Alberto Zaniboni , Alessandro Passardi , Tiziana Pia Latiano , Valentina Fanotto , Samantha Di Donato , Michele Prisciandaro , Francesca Bergamo , Gianluca Masi , Gabriella Fontanini , Clara Ugolini , Chiara Cremolini

Total neoadjuvant treatment and organ preservation strategies in the management of localized rectal cancer: A narrative review and evidence-based algorithm.

Critical reviews in oncology/hematology

Avec: Beatrice Borelli , Marco Maria Germani , Martina Carullo , Roberto Mattioni , Bruno Manfredi , Aldo Sainato , Piercarlo Rossi , Paola Vagli , Riccardo Balestri , Piero Buccianti , Luca Morelli , Carlotta Antoniotti , Chiara Cremolini , Gianluca Masi , Roberto Moretto

Cetuximab as third-line rechallenge plus either irinotecan or avelumab is an effective treatment in metastatic colorectal cancer patients with baseline plasma RAS/BRAF wild-type circulating tumor DNA: Individual patient data pooled analysis of CRICKET and CAVE trials.

Cancer medicine

Avec: G Martini , D Ciardiello , V Famiglietti , D Rossini , C Antoniotti , T Troiani , S Napolitano , L Esposito , T P Latiano , E Maiello , M Del Re , S Lonardi , G Aprile , D Santini , G Masi , A Avallone , N Normanno , F Pietrantonio , C Pinto , F Ciardiello , C Cremolini , E Martinelli

An Immune-Related Gene Expression Signature Predicts Benefit from Adding Atezolizumab to FOLFOXIRI plus Bevacizumab in Metastatic Colorectal Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Carlotta Antoniotti , Alessandra Boccaccino , Robert Seitz , Mirella Giordano , Aurélie Catteau , Daniele Rossini , Filippo Pietrantonio , Lisa Salvatore , Kimberly McGregor , Francesca Bergamo , Veronica Conca , Simone Leonetti , Federica Morano , Giorgio Papiani , Emiliano Tamburini , Maria Bensi , Sabina Murgioni , Douglas Teller Ross , Alessandro Passardi , Isabelle Boquet , Tyler J Nielsen , Jérôme Galon , Matthew Gordon Varga , Brock L Schweitzer , Chiara Cremolini

Transcriptomic Signatures of MSI-High Metastatic Colorectal Cancer Predict Efficacy of Immune Checkpoint Inhibitors.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Claire Gallois , Matteo Landi , Julien Taieb , Marine Sroussi , Bahar Saberzadeh-Ardestani , Antoine Cazelles , Sara Lonardi , Francesca Bergamo , Rossana Intini , Giulia Maddalena , Filippo Pietrantonio , Francesca Corti , Margherita Ambrosini , Antonia Martinetti , Marco Maria Germani , Chiara Boccaccio , Guglielmo Vetere , Sophie Mouillet-Richard , Aurélien de Reynies , Frank A Sinicrope , Chiara Cremolini , Pierre Laurent-Puig

Dynamic Profiling of the Immune Tumor Microenvironment in Locally Advanced Gastric Cancer Treated with Perioperative Chemotherapy.

Oncology

Avec: Irene Pecora , Clara Ugolini , Riccardo Giannini , Mirella Giordano , Caterina Vivaldi , Monica Lencioni , Stefano Santi , Valentina Massa , Giovanni Pallabazzer , Silvia Catanese , Francesca Salani , Mario Antonio Belluomini , Enrico Vasile , Chiara Cremolini , Gabriella Fontanini , Gianluca Masi , Lorenzo Fornaro

Evaluation of Intratumoral Response Heterogeneity in Metastatic Colorectal Cancer and Its Impact on Patient Overall Survival: Findings from 10,551 Patients in the ARCAD Database.

Cancers

Avec: Fang-Shu Ou , Daniel H Ahn , Jesse G Dixon , Axel Grothey , Yiyue Lou , Pashtoon M Kasi , Joleen M Hubbard , Eric Van Cutsem , Leonard B Saltz , Hans-Joachim Schmoll , Richard M Goldberg , Alan P Venook , Paulo Hoff , Jean-Yves Douillard , J Randolph Hecht , Herbert Hurwitz , Cornelis J A Punt , Miriam Koopman , Carsten Bokemeyer , Charles S Fuchs , Eduardo Diaz-Rubio , Niall C Tebbutt , Chiara Cremolini , Fairooz F Kabbinavar , Tanios Bekaii-Saab , Benoist Chibaudel , Takayuki Yoshino , John Zalcberg , Richard A Adams , Aimery de Gramont , Qian Shi

Fruquintinib versus placebo in patients with refractory metastatic colorectal cancer (FRESCO-2): an international, multicentre, randomised, double-blind, phase 3 study.

Lancet (London, England)

Avec: Arvind Dasari , Sara Lonardi , Rocio Garcia-Carbonero , Elena Elez , Takayuki Yoshino , Alberto Sobrero , James Yao , Pilar García-Alfonso , Judit Kocsis , Antonio Cubillo Gracian , Andrea Sartore-Bianchi , Taroh Satoh , Violaine Randrian , Jiri Tomasek , Geoff Chong , Andrew Scott Paulson , Toshiki Masuishi , Jeremy Jones , Tibor Csőszi , Chiara Cremolini , Francois Ghiringhelli , Ardaman Shergill , Howard S Hochster , John Krauss , Ali Bassam , Michel Ducreux , Anneli Elme , Laurence Faugeras , Stefan Kasper , Eric Van Cutsem , Dirk Arnold , Shivani Nanda , Zhao Yang , William R Schelman , Marek Kania , Josep Tabernero , Cathy Eng , Auteur inconnu

Anti-EGFR Rechallenge in Patients With Refractory ctDNA RAS/BRAF wt Metastatic Colorectal Cancer: A Nonrandomized Controlled Trial.

JAMA network open

Avec: Davide Ciardiello , Erika Martinelli , Teresa Troiani , Gianluca Mauri , Daniele Rossini , Giulia Martini , Stefania Napolitano , Vincenzo Famiglietti , Sara Del Tufo , Gianluca Masi , Daniele Santini , Antonio Avallone , Filippo Pietrantonio , Sara Lonardi , Massimo Di Maio , Maria Giulia Zampino , Nicola Fazio , Alberto Bardelli , Salvatore Siena , Chiara Cremolini , Andrea Sartore-Bianchi , Fortunato Ciardiello

Waiting for the "liquid revolution" in the adjuvant treatment of colon cancer patients: a review of ongoing trials.

Cancer treatment reviews

Avec: V Conca , P Ciracì , C Boccaccio , A Minelli , C Antoniotti , C Cremolini

AXL is a predictor of poor survival and of resistance to anti-EGFR therapy in RAS wild-type metastatic colorectal cancer.

European journal of cancer (Oxford, England : 1990)

Avec: Claudia Cardone , Bernadette Blauensteiner , Veronica Moreno-Viedma , Giulia Martini , Vittorio Simeon , Pietro P Vitiello , Davide Ciardiello , Valentina Belli , Nunzia Matrone , Teresa Troiani , Floriana Morgillo , Federica Zito Marino , Monica Dentice , Annarita Nappi , Alessandra Boccaccino , Carlotta Antoniotti , Chiara Cremolini , Filippo Pietrantonio , Gerald W Prager , Nicola Normanno , Evaristo Maiello , Guillem Argiles , Elena Elez , Giuseppe Signoriello , Renato Franco , Alfredo Falcone , Josep Tabernero , Maria Sibilia , Fortunato Ciardiello , Erika Martinelli

Immune Checkpoint Inhibitors in pMMR Metastatic Colorectal Cancer: A Tough Challenge.

Cancers

Avec: Federica Marmorino , Alessandra Boccaccino , Marco Maria Germani , Alfredo Falcone , Chiara Cremolini

Prognostic and Predictive Biomarkers in Patients with Metastatic Colorectal Cancer Receiving Regorafenib.

Molecular cancer therapeutics

Avec: Yingmiao Liu , Jing Lyu , Kirsten Bell Burdett , Alexander B Sibley , Ace J Hatch , Mark D Starr , John C Brady , Kelli Hammond , Federica Marmorino , Daniele Rossini , Richard M Goldberg , Alfredo Falcone , Chiara Cremolini , Kouros Owzar , Anastasia Ivanova , Dominic T Moore , Michael S Lee , Hanna K Sanoff , Federico Innocenti , Andrew B Nixon

The Pan-Immune-Inflammation Value is a new prognostic biomarker in metastatic colorectal cancer: results from a pooled-analysis of the Valentino and TRIBE first-line trials.

British journal of cancer

Avec: Giovanni Fucà , Vincenzo Guarini , Carlotta Antoniotti , Federica Morano , Roberto Moretto , Salvatore Corallo , Federica Marmorino , Sara Lonardi , Lorenza Rimassa , Andrea Sartore-Bianchi , Beatrice Borelli , Marco Tampellini , Sara Bustreo , Matteo Claravezza , Alessandra Boccaccino , Roberto Murialdo , Alberto Zaniboni , Gianluca Tomasello , Fotios Loupakis , Vincenzo Adamo , Giuseppe Tonini , Enrico Cortesi , Filippo de Braud , Chiara Cremolini , Filippo Pietrantonio

Single Nucleotide Polymorphisms in MiRNA Binding Sites of Nucleotide Excision Repair-Related Genes Predict Clinical Benefit of Oxaliplatin in FOLFOXIRI Plus Bevacizumab: Analysis of the TRIBE Trial.

Cancers

Avec: Mitsukuni Suenaga , Marta Schirripa , Shu Cao , Wu Zhang , Dongyun Yang , Chiara Cremolini , Sabina Murgioni , Sara Lonardi , Yan Ning , Satoshi Okazaki , Martin D Berger , Yuji Miyamoto , Afsaneh Barzi , Fotios Loupakis , Alfredo Falcone , Heinz-Josef Lenz

A validated prognostic classifier for

European journal of cancer (Oxford, England : 1990)

Avec: Fotios Loupakis , Rossana Intini , Chiara Cremolini , Armando Orlandi , Andrea Sartore-Bianchi , Filippo Pietrantonio , Nicoletta Pella , Andrea Spallanzani , Emanuela Dell'Aquila , Mario Scartozzi , Emmanuele De Luca , Lorenza Rimassa , Vincenzo Formica , Francesco Leone , Lorenzo Calvetti , Giuseppe Aprile , Lorenzo Antonuzzo , Federica Urbano , Hans Prenen , Francesca Negri , Samantha Di Donato , Pasquale Buonandi , Gianluca Tomasello , Antonio Avallone , Fable Zustovich , Roberto Moretto , Carlotta Antoniotti , Lisa Salvatore , Maria Alessandra Calegari , Salvatore Siena , Federica Morano , Elena Ongaro , Stefano Cascinu , Daniele Santini , Pina Ziranu , Marta Schirripa , Federica Buggin , Alessandra Anna Prete , Ilaria Depetris , Paola Biason , Sara Lonardi , Vittorina Zagonel , Matteo Fassan , Massimo Di Maio

Negative Hyperselection of Patients With

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Avec: Federica Morano , Salvatore Corallo , Sara Lonardi , Alessandra Raimondi , Chiara Cremolini , Lorenza Rimassa , Roberto Murialdo , Alberto Zaniboni , Andrea Sartore-Bianchi , Gianluca Tomasello , Patrizia Racca , Matteo Clavarezza , Vincenzo Adamo , Federica Perrone , Annunziata Gloghini , Elena Tamborini , Adele Busico , Antonia Martinetti , Federica Palermo , Fotios Loupakis , Massimo Milione , Giovanni Fucà , Maria Di Bartolomeo , Filippo de Braud , Filippo Pietrantonio

AMPK variant, a candidate of novel predictor for chemotherapy in metastatic colorectal cancer: A meta-analysis using TRIBE, MAVERICC and FIRE3.

International journal of cancer

Avec: Ryuma Tokunaga , Shu Cao , Madiha Naseem , Francesca Battaglin , Jae Ho Lo , Hiroyuki Arai , Fotios Loupakis , Sebastian Stintzing , Alberto Puccini , Martin D Berger , Shivani Soni , Wu Zhang , Christoph Mancao , Bodour Salhia , Shannon M Mumenthaler , Daniel J Weisenberger , Gangning Liang , Chiara Cremolini , Volker Heinemann , Alfredo Falcone , Joshua Millstein , Heinz-Josef Lenz

Prognostic Effect of Adenosine-related Genetic Variants in Metastatic Colorectal Cancer Treated With Bevacizumab-based Chemotherapy.

Clinical colorectal cancer

Avec: Ryuma Tokunaga , Shu Cao , Madiha Naseem , Jae Ho Lo , Francesca Battaglin , Alberto Puccini , Martin D Berger , Shivani Soni , Joshua Millstein , Wu Zhang , Sebastian Stintzing , Fotios Loupakis , Chiara Cremolini , Volker Heinemann , Alfredo Falcone , Heinz-Josef Lenz

Clinical Validation of a Machine-learning-derived Signature Predictive of Outcomes from First-line Oxaliplatin-based Chemotherapy in Advanced Colorectal Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Jim P Abraham , Daniel Magee , Chiara Cremolini , Carlotta Antoniotti , David D Halbert , Joanne Xiu , Phillip Stafford , Donald A Berry , Matthew J Oberley , Anthony F Shields , John L Marshall , Mohamed E Salem , Alfredo Falcone , Axel Grothey , Michael J Hall , Alan P Venook , Heinz-Josef Lenz , Anthony Helmstetter , W Michael Korn , David B Spetzler

A polymorphism in the cachexia-associated gene INHBA predicts efficacy of regorafenib in patients with refractory metastatic colorectal cancer.

PloS one

Avec: Yuji Miyamoto , Marta Schirripa , Mitsukuni Suenaga , Shu Cao , Wu Zhang , Satoshi Okazaki , Martin D Berger , Satoshi Matsusaka , Dongyun Yang , Yan Ning , Hideo Baba , Fotios Loupakis , Sara Lonardi , Filippo Pietrantonio , Beatrice Borelli , Chiara Cremolini , Toshiharu Yamaguchi , Heinz-Josef Lenz

Validation of the Colon Life nomogram in patients with refractory metastatic colorectal cancer enrolled in the RECOURSE trial.

Tumori

Avec: Filippo Pietrantonio , Giovanni Fucà , Paolo Manca , Filippo Pagani , Alessandra Raimondi , Michele Prisciandaro , Giovanni Randon , Francesca Corti , Filippo de Braud , Chiara Cremolini , Rosalba Miceli

EGFR Amplification in Metastatic Colorectal Cancer.

Journal of the National Cancer Institute

Avec: Giovanni Randon , Rona Yaeger , Jaclyn F Hechtman , Paolo Manca , Giovanni Fucà , Henry Walch , Jeeyun Lee , Elena Élez , Jenny Seligmann , Benedetta Mussolin , Filippo Pagani , Marco Maria Germani , Margherita Ambrosini , Daniele Rossini , Margherita Ratti , Francesc Salvà , Susan D Richman , Henry Wood , Gouri Nanjangud , Annunziata Gloghini , Massimo Milione , Alberto Bardelli , Filippo de Braud , Federica Morano , Chiara Cremolini , Filippo Pietrantonio

RAS as a positive predictive biomarker: focus on lung and colorectal cancer patients.

European journal of cancer (Oxford, England : 1990)

Avec: Umberto Malapelle , Francesco Passiglia , Chiara Cremolini , Maria Lucia Reale , Francesco Pepe , Pasquale Pisapia , Antonio Avallone , Diego Cortinovis , Alfonso De Stefano , Matteo Fassan , Gabriella Fontanini , Domenico Galetta , Calogero Lauricella , Angela Listì , Fotios Loupakis , Fabio Pagni , Filippo Pietrantonio , Sara Pilotto , Luisella Righi , Andrea Sartore Bianchi , Hector Soto Parra , Marcello Tiseo , Michela Verzè , Giancarlo Troncone , Silvia Novello

Advanced Nanotechnology for Enhancing Immune Checkpoint Blockade Therapy.

Nanomaterials (Basel, Switzerland)

Avec: Chiara Cremolini , Emanuela Vitale , Raffaella Rastaldo , Claudia Giachino

[Clinical applications of bevacizumab in the treatment of colorectal and ovarian cancer.]

Recenti progressi in medicina

Avec: Romano Danesi , Chiara Cremolini , Francesca Ciccarone , Domenica Lorusso

Homologous Recombination Deficiency Alterations in Colorectal Cancer: Clinical, Molecular, and Prognostic Implications.

Journal of the National Cancer Institute

Avec: Roberto Moretto , Andrew Elliott , Jian Zhang , Hiroyuki Arai , Marco Maria Germani , Veronica Conca , Joanne Xiu , Phillip Stafford , Matthew Oberley , Jim Abraham , David Spetzler , Daniele Rossini , Carlotta Antoniotti , John Marshall , Anthony Shields , Gilberto Lopes , Sara Lonardi , Filippo Pietrantonio , Gianluca Tomasello , Alessandro Passardi , Emiliano Tamburini , Daniele Santini , Giuseppe Aprile , Gianluca Masi , Alfredo Falcone , Heinz-Josef Lenz , Michael Korn , Chiara Cremolini

Tumour mutational burden predicts resistance to EGFR/BRAF blockade in BRAF-mutated microsatellite stable metastatic colorectal cancer.

European journal of cancer (Oxford, England : 1990)

Avec: Giovanni Randon , Rossana Intini , Chiara Cremolini , Elena Elez , Michael J Overman , Jeeyun Lee , Paolo Manca , Francesca Bergamo , Filippo Pagani , Maria Antista , Valentina Angerilli , Francisco Javier Ros Montaña , Daniele Lavacchi , Alessandra Boccaccino , Giovanni Fucà , Silvia Brich , Laura Cattaneo , Matteo Fassan , Filippo Pietrantonio , Sara Lonardi

Early modulation of Angiopoietin-2 plasma levels predicts benefit from regorafenib in patients with metastatic colorectal cancer.

European journal of cancer (Oxford, England : 1990)

Avec: Carlotta Antoniotti , Federica Marmorino , Alessandra Boccaccino , Silvia Martini , Maria Antista , Daniele Rossini , Valentina Zuco , Michele Prisciandaro , Veronica Conca , Gemma Zucchelli , Beatrice Borelli , Paola Cosentino , Marco M Germani , Maria F Bosco , Martina Carullo , Guglielmo Vetere , Roberto Moretto , Mirella Giordano , Gianluca Masi , Filippo Pietrantonio , Nadia Zaffaroni , Chiara Cremolini

The management of colorectal liver metastases amenable of surgical resection: How to shape treatment strategies according to clinical, radiological, pathological and molecular features.

Cancer treatment reviews

Avec: Marco Maria Germani , Beatrice Borelli , Piero Boraschi , Carlotta Antoniotti , Clara Ugolini , Lucio Urbani , Luca Morelli , Gabriella Fontanini , Gianluca Masi , Chiara Cremolini , Roberto Moretto

Encorafenib plus cetuximab with or without binimetinib in patients with BRAF V600E-mutated metastatic colorectal cancer: real-life data from an Italian multicenter experience.

ESMO open

Avec: A Boccaccino , B Borelli , R Intini , M Antista , M Bensi , D Rossini , A Passardi , S Tamberi , R Giampieri , L Antonuzzo , L Noto , G Roviello , C Zichi , M Salati , A Puccini , C Noto , A Parisi , K Rihawi , M Persano , V Crespi , M Libertini , M Giordano , R Moretto , S Lonardi , C Cremolini

Genetic variants involved in the cGAS-STING pathway predict outcome in patients with metastatic colorectal cancer: Data from FIRE-3 and TRIBE trials.

European journal of cancer (Oxford, England : 1990)

Avec: Jingyuan Wang , Yi Xiao , Fotios Loupakis , Sebastian Stintzing , Yan Yang , Hiroyuki Arai , Francesca Battaglin , Natsuko Kawanishi , Priya Jayachandran , Shivani Soni , Wu Zhang , Christoph Mancao , Chiara Cremolini , Tianshu Liu , Volker Heinemann , Alfredo Falcone , Lin Shen , Joshua Millstein , Heinz-Josef Lenz

Negative Ultraselection of Patients With

JCO precision oncology

Avec: Giovanni Randon , Giulia Maddalena , Marco Maria Germani , Chiara Carlotta Pircher , Paolo Manca , Francesca Bergamo , Mirella Giordano , Caterina Sposetti , Aldo Montagna , Guglielmo Vetere , Luca Zambelli , Cosimo Rasola , Alessandra Boccaccino , Filippo Pagani , Margherita Ambrosini , Marco Massafra , Gabriella Fontanini , Massimo Milione , Matteo Fassan , Chiara Cremolini , Sara Lonardi , Filippo Pietrantonio

Treatments after second progression in metastatic colorectal cancer: A pooled analysis of the TRIBE and TRIBE2 studies.

European journal of cancer (Oxford, England : 1990)

Avec: Daniele Rossini , Marco M Germani , Sara Lonardi , Filippo Pietrantonio , Emanuela Dell'Aquila , Beatrice Borelli , Giacomo Allegrini , Giulia Maddalena , Giovanni Randon , Federica Marmorino , Alberto Zaniboni , Angela Buonadonna , Alessandra Boccaccino , Veronica Conca , Carlotta Antoniotti , Alessandro Passardi , Gianluca Masi , Chiara Cremolini

Temozolomide Followed by Combination With Low-Dose Ipilimumab and Nivolumab in Patients With Microsatellite-Stable, O

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Avec: Federica Morano , Alessandra Raimondi , Filippo Pagani , Sara Lonardi , Lisa Salvatore , Chiara Cremolini , Sabina Murgioni , Giovanni Randon , Federica Palermo , Lorenzo Antonuzzo , Nicoletta Pella , Patrizia Racca , Michele Prisciandaro , Monica Niger , Francesca Corti , Francesca Bergamo , Alberto Zaniboni , Margherita Ratti , Michele Palazzo , Celeste Cagnazzo , Maria Alessandra Calegari , Federica Marmorino , Iolanda Capone , Elena Conca , Adele Busico , Silvia Brich , Elena Tamborini , Federica Perrone , Massimo Di Maio , Massimo Milione , Maria Di Bartolomeo , Filippo de Braud , Filippo Pietrantonio

Atypical

JCO precision oncology

Avec: Filippo Pietrantonio , Rona Yaeger , Alexa B Schrock , Giovanni Randon , Sandra Romero-Cordoba , Daniele Rossini , Giovanni Fucà , Jeffrey S Ross , Daisuke Kotani , Russell Madison , Seung Tae Kim , Lisa Salvatore , Alessandra Raimondi , Filippo Pagani , Beatrice Borelli , Federica Perrone , Maria Di Bartolomeo , Vincent A Miller , Siraj M Ali , Jeeyun Lee , Takayuki Yoshino , Filippo de Braud , Alfredo Falcone , Jaclyn F Hechtman , Chiara Cremolini

Upper transversal hepatectomy with double hepatic vein resection and reconstruction to treat colorectal cancer liver metastases at the hepatocaval confluence: a strategy to achieve R0 liver-sparing resection.

Langenbeck's archives of surgery

Avec: Lucio Urbani , Nicolò Roffi , Stefano Signori , Riccardo Balestri , Piero Colombatto , Gabriella Licitra , Chiara Leoni , Daniele Meiattini , Roberto Moretto , Chiara Cremolini , Gianluca Masi , Piero Boraschi , Francesca Quilici , Piero Buccianti , Marco Puccini

Comparison of digital PCR systems for the analysis of liquid biopsy samples of patients affected by lung and colorectal cancer.

Clinica chimica acta; international journal of clinical chemistry

Avec: Stefania Crucitta , Martina Ruglioni , Claudia Novi , Mascia Manganiello , Roberta Arici , Iacopo Petrini , Eleonora Pardini , Federico Cucchiara , Federica Marmorino , Chiara Cremolini , Stefano Fogli , Romano Danesi , Marzia Del Re

TK-1, TP, Ang-2, and Tie-2 mRNA expression in plasma-derived microvesicles of chemo-refractory metastatic colorectal cancer patients.

Tumori

Avec: Beatrice Borelli , Stefania Crucitta , Alessandra Boccaccino , Maria Antista , Carlotta Antoniotti , Federica Marmorino , Daniele Rossini , Veronica Conca , Marco Maria Germani , Leonardo Provenzano , Andrea Spagnoletti , Alberto Giovanni Leone , Federico Cucchiara , Filippo Pietrantonio , Marzia Del Re , Romano Danesi , Gianluca Masi , Chiara Cremolini , Roberto Moretto

Primary tumour side as a driver for treatment choice in RAS wild-type metastatic colorectal cancer patients: a systematic review and pooled analysis of randomised trials.

European journal of cancer (Oxford, England : 1990)

Avec: Daniele Rossini , Alessandra Boccaccino , Martina Carullo , Carlotta Antoniotti , Giovanni Dima , Paolo Ciracì , Federica Marmorino , Roberto Moretto , Gianluca Masi , Chiara Cremolini

Light on life: immunoscore immune-checkpoint, a predictor of immunotherapy response.

Oncoimmunology

Avec: Assia Hijazi , Carlotta Antoniotti , Chiara Cremolini , Jérôme Galon

Divarasib plus cetuximab in KRAS G12C-positive colorectal cancer: a phase 1b trial.

Nature medicine

Avec: Jayesh Desai , Guzman Alonso , Se Hyun Kim , Andres Cervantes , Thomas Karasic , Laura Medina , Einat Shacham-Shmueli , Rasha Cosman , Alejandro Falcon , Eelke Gort , Tormod Guren , Erminia Massarelli , Wilson H Miller , Luis Paz-Ares , Hans Prenen , Alessio Amatu , Chiara Cremolini , Tae Won Kim , Victor Moreno , Sai-Hong I Ou , Alessandro Passardi , Adrian Sacher , Armando Santoro , Rafal Stec , Susanna Ulahannan , Kathryn Arbour , Patricia Lorusso , Jia Luo , Manish R Patel , Yoonha Choi , Zhen Shi , Sandhya Mandlekar , Mark T Lin , Stephanie Royer-Joo , Julie Chang , Tomi Jun , Neekesh V Dharia , Jennifer L Schutzman , Auteur inconnu , Sae-Won Han

Prognostic value of liver metastases in colorectal cancer treated by systemic therapy: An ARCAD pooled analysis.

European journal of cancer (Oxford, England : 1990)

Avec: Romain Cohen , Morteza Raeisi , Benoist Chibaudel , Qian Shi , Takayuki Yoshino , John R Zalcberg , Richard Adams , Chiara Cremolini , Eric Van Cutsem , Volker Heinemann , Josep Tabernero , Cornelis J A Punt , Dirk Arnold , Herbert I Hurwitz , Jean-Yves Douillard , Alan P Venook , Leonard B Saltz , Timothy S Maughan , Fairooz Kabbinavar , Carsten Bokemeyer , Axel Grothey , Robert J Mayer , Richard Kaplan , Niall C Tebbutt , J Randolph Hecht , Bruce J Giantonio , Eduardo Díaz-Rubio , Alberto F Sobrero , Marc Peeters , Miriam Koopman , Richard M Goldberg , Thierry Andre , Aimery de Gramont

Treatments after progression to first-line FOLFOXIRI and bevacizumab in metastatic colorectal cancer: a pooled analysis of TRIBE and TRIBE2 studies by GONO.

British journal of cancer

Avec: Daniele Rossini , Sara Lonardi , Carlotta Antoniotti , Daniele Santini , Gianluca Tomasello , Paola Ermacora , Marco Maria Germani , Francesca Bergamo , Vincenzo Ricci , Salvatore Caponnetto , Roberto Moretto , Alberto Zaniboni , Filippo Pietrantonio , Angela Buonadonna , Giuliana Ritorto , Gianluca Masi , Tiziana Pia Latiano , Stefania Rapisardi , Alfredo Falcone , Chiara Cremolini

Immunogenic cell death pathway polymorphisms for predicting oxaliplatin efficacy in metastatic colorectal cancer.

Journal for immunotherapy of cancer

Avec: Hiroyuki Arai , Yi Xiao , Fotios Loupakis , Natsuko Kawanishi , Jingyuan Wang , Francesca Battaglin , Shivani Soni , Wu Zhang , Christoph Mancao , Bodour Salhia , Shannon M Mumenthaler , Daniel J Weisenberger , Gangning Liang , Chiara Cremolini , Alfredo Falcone , Joshua Millstein , Heinz-Josef Lenz

Réseau de co-auteurs

Chiara Cremolini 95 collaborations

Filippo Pietrantonio 49 collaborations

Sara Lonardi 35 collaborations

Alfredo Falcone 32 collaborations

Carlotta Antoniotti 30 collaborations

Gianluca Masi 27 collaborations

Roberto Moretto 25 collaborations

Daniele Rossini 24 collaborations

Fotios Loupakis 20 collaborations

Federica Marmorino 20 collaborations

Alessandra Boccaccino 19 collaborations

Beatrice Borelli 18 collaborations

Federica Morano 17 collaborations

Francesca Bergamo 16 collaborations

Veronica Conca 16 collaborations

Heinz-Josef Lenz 15 collaborations

Giovanni Randon 14 collaborations

Giovanni Fucà 14 collaborations

Alessandra Raimondi 13 collaborations

Maria Di Bartolomeo 13 collaborations

Filippo de Braud 13 collaborations

Gabriella Fontanini 13 collaborations

Marco Maria Germani 13 collaborations

Lisa Salvatore 12 collaborations

Alberto Zaniboni 11 collaborations

Mirella Giordano 11 collaborations

Salvatore Corallo 10 collaborations

Alessandro Passardi 10 collaborations

Michele Prisciandaro 10 collaborations

Wu Zhang 10 collaborations

Maria Antista 9 collaborations

Marta Schirripa 9 collaborations

Giuseppe Aprile 9 collaborations

Margherita Ambrosini 9 collaborations

Rossana Intini 9 collaborations

Emiliano Tamburini 9 collaborations

Daniele Santini 9 collaborations

Filippo Pagani 8 collaborations

Francesca Corti 8 collaborations

Shu Cao 8 collaborations

Andrea Sartore-Bianchi 8 collaborations

Matteo Fassan 8 collaborations

Massimo Milione 7 collaborations

Sebastian Stintzing 7 collaborations

Martin D Berger 7 collaborations

Francesca Battaglin 7 collaborations

Shivani Soni 7 collaborations

Volker Heinemann 7 collaborations

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Nicoletta Pella 7 collaborations

Monica Niger 6 collaborations

Gemma Zucchelli 6 collaborations

Sabina Murgioni 6 collaborations

Mario Scartozzi 6 collaborations

Paolo Manca 6 collaborations

Joshua Millstein 6 collaborations

Massimo Di Maio 6 collaborations

Clara Ugolini 6 collaborations

Martina Carullo 6 collaborations

Takayuki Yoshino 6 collaborations

Luca Morelli 6 collaborations

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Hiroyuki Arai 5 collaborations

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Josep Tabernero 5 collaborations

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Serena Saggio 4 collaborations

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Filippo De Braud 4 collaborations

Evaristo Maiello 4 collaborations

Romano Danesi 4 collaborations

Javier Ros 4 collaborations

Rosalba Miceli 4 collaborations

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Yan Ning 4 collaborations

Christoph Mancao 4 collaborations

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Roberto Murialdo 4 collaborations

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S Lonardi 3 collaborations

None None 3 collaborations

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R Moretto 2 collaborations

G Aprile 2 collaborations

G Masi 2 collaborations

M Libertini 2 collaborations

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