Christopher Rynn

Affiliations

Centre for Anatomy and Human Identification, University of Dundee, Scotland, UK.

Publications (13)

Design and Synthesis of Inhibitors of the E3 Ligase SMAD Specific E3 Ubiquitin Protein Ligase 1 as a Treatment for Lung Remodeling in Pulmonary Arterial Hypertension.

Journal of medicinal chemistry

Avec: Duncan E Shaw , Nichola Smith , Rene Beerli , Simona Cotesta , Pier-Luca D'Alessandro , Anne-Marie Edwards , Rene Lattmann , Dimitrios Lizos , Robert Pulz , Lisa Rooney , Bindi Sohal , Caroline Rynn , Jessica Taylor , Thomas Troxler , Gareth Williams , Sabine Guth , David Rowlands

Facial average soft tissue depth variation based on skeletal classes in Indonesian adult population: A retrospective lateral cephalometric study.

Legal medicine (Tokyo, Japan)

Avec: Erli Sarilita , Christopher Rynn , Peter A Mossey , Sue Black , Fahmi Oscandar

Craniofacial reconstruction of the Indus Valley Civilization individuals found at 4500-year-old Rakhigarhi cemetery.

Anatomical science international

Avec: Won Joon Lee , Vasant Shinde , Yong Jun Kim , Eun Jin Woo , Nilesh Jadhav , Pranjali Waghmare , Yogesh Yadav , Avradeep Munshi , Amrithavalli Panyam , Malavika Chatterjee , Chang Seok Oh , Jong Ha Hong , Caroline M Wilkinson , Christopher Rynn , Dong Hoon Shin

Chemical, Analytical and Pharmacokinetic Characterisation of RO7304898, an API Consisting of Two Rapidly Interconverting Diastereoisomers.

Pharmaceutical research

Avec: Katja Heinig , Filippo Sladojevich , Jeannine Petrig Schaffland , Georg Jaeschke , Alfred Ross , Philipp Koldewey , Saša M Miladinović , Jin Wang , Caroline Rynn

Estimation of the mandibular dimensions from linear cranial measurements for use in craniofacial reconstruction: A preliminary study.

Legal medicine (Tokyo, Japan)

Avec: Josie Ide , Christopher Rynn

Industry Perspective on the Pharmacokinetic and Absorption, Distribution, Metabolism, and Excretion Characterization of Heterobifunctional Protein Degraders.

Drug metabolism and disposition: the biological fate of chemicals

Avec: Laurie P Volak , Heide Marika Duevel , Sara Humphreys , David Nettleton , Colin Phipps , Andy Pike , Caroline Rynn , Paul Scott-Stevens , Donglu Zhang , Michael Zientek

Zygomaticus major muscle bony attachment site: a Thiel-embalmed cadaver study.

Morphologie : bulletin de l'Association des anatomistes

Avec: E Sarilita , C Rynn , P A Mossey , S Black

Fundamental aspects of DMPK optimization of targeted protein degraders.

Drug discovery today

Avec: Carina Cantrill , Prasoon Chaturvedi , Caroline Rynn , Jeannine Petrig Schaffland , Isabelle Walter , Matthias B Wittwer

Preclinical Characterization of a Next-Generation Brain Permeable, Paradox Breaker BRAF Inhibitor.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Jürgen Wichmann , Caroline Rynn , Thomas Friess , Jeannine Petrig-Schaffland , Martin Kornacker , Cornelia Handl , Jasmin Emmenegger , Jan Eckmann , Frank Herting , Nicolas Frances , Daniel Hunziker , Daniela Krummenacher , Dominik Rüttinger , Alison Ribeiro , Marina Bacac , Alessandro Brigo , David S Hewings , Reinhard Dummer , Mitchell P Levesque , Gabriel Schnetzler , Bruno Martoglio , James R Bischoff , Piergiorgio Pettazzoni

A revised nose tip shape validation method for facial reconstruction based on CT data from a modern German population.

Legal medicine (Tokyo, Japan)

Avec: Isabel D Burton , Christopher Rynn , Nicolle Thiemann-Freudenstein

Translating pharmacology models effectively to predict therapeutic benefit.

Drug discovery today

Avec: Sherri Dudal , Caterina Bissantz , Antonello Caruso , Pascale David-Pierson , Wouter Driessen , Erich Koller , Ben-Fillippo Krippendorff , Martin Lechmann , Andrés Olivares-Morales , Axel Paehler , Caroline Rynn , Dietrich Türck , Arthur Van De Vyver , Ken Wang , Lotte Winther

Discovery of Novel Allosteric EGFR L858R Inhibitors for the Treatment of Non-Small-Cell Lung Cancer as a Single Agent or in Combination with Osimertinib.

Journal of medicinal chemistry

Avec: Ulrike Obst-Sander , Antonio Ricci , Bernd Kuhn , Thomas Friess , Philipp Koldewey , Andreas Kuglstatter , David Hewings , Annick Goergler , Sandra Steiner , Daniel Rueher , Marie-Paule Imhoff , Noemi Raschetti , Hans-Peter Marty , Aline Dietzig , Caroline Rynn , Andreas Ehler , Dominique Burger , Martin Kornacker , Jeannine Petrig Schaffland , Frank Herting , William Pao , James R Bischoff , Bruno Martoglio , Yvonne Alice Nagel , Georg Jaeschke

A translational strategy employing physiologically based modelling to predict the pharmacological active dose of RO7119929, an oral prodrug of a targeted cancer immunotherapy TLR7 agonist.

Xenobiotica; the fate of foreign compounds in biological systems

Avec: Caroline Rynn , Kenichi Umehara , Tianyi Jiang , Malika Ait-Goughoulte , Neil Parrott

Réseau de co-auteurs

Caroline Rynn 8 collaborations

Jeannine Petrig Schaffland 3 collaborations

Georg Jaeschke 2 collaborations

Philipp Koldewey 2 collaborations

Thomas Friess 2 collaborations

Martin Kornacker 2 collaborations

Frank Herting 2 collaborations

Bruno Martoglio 2 collaborations

James R Bischoff 2 collaborations

Duncan E Shaw 1 collaboration

Nichola Smith 1 collaboration

Rene Beerli 1 collaboration

Simona Cotesta 1 collaboration

Pier-Luca D'Alessandro 1 collaboration

Anne-Marie Edwards 1 collaboration

Rene Lattmann 1 collaboration

Dimitrios Lizos 1 collaboration

Robert Pulz 1 collaboration

Lisa Rooney 1 collaboration

Bindi Sohal 1 collaboration

Jessica Taylor 1 collaboration

Thomas Troxler 1 collaboration

Gareth Williams 1 collaboration

Sabine Guth 1 collaboration

David Rowlands 1 collaboration

Erli Sarilita 1 collaboration

Peter A Mossey 1 collaboration

Sue Black 1 collaboration

Fahmi Oscandar 1 collaboration

Won Joon Lee 1 collaboration

Vasant Shinde 1 collaboration

Yong Jun Kim 1 collaboration

Eun Jin Woo 1 collaboration

Nilesh Jadhav 1 collaboration

Pranjali Waghmare 1 collaboration

Yogesh Yadav 1 collaboration

Avradeep Munshi 1 collaboration

Amrithavalli Panyam 1 collaboration

Malavika Chatterjee 1 collaboration

Chang Seok Oh 1 collaboration

Jong Ha Hong 1 collaboration

Caroline M Wilkinson 1 collaboration

Dong Hoon Shin 1 collaboration

Katja Heinig 1 collaboration

Filippo Sladojevich 1 collaboration

Alfred Ross 1 collaboration

Saša M Miladinović 1 collaboration

Jin Wang 1 collaboration

Josie Ide 1 collaboration

Laurie P Volak 1 collaboration

Heide Marika Duevel 1 collaboration

Sara Humphreys 1 collaboration

David Nettleton 1 collaboration

Colin Phipps 1 collaboration

Andy Pike 1 collaboration

Paul Scott-Stevens 1 collaboration

Donglu Zhang 1 collaboration

Michael Zientek 1 collaboration

E Sarilita 1 collaboration

C Rynn 1 collaboration

P A Mossey 1 collaboration

S Black 1 collaboration

Carina Cantrill 1 collaboration

Prasoon Chaturvedi 1 collaboration

Isabelle Walter 1 collaboration

Matthias B Wittwer 1 collaboration

Jürgen Wichmann 1 collaboration

Jeannine Petrig-Schaffland 1 collaboration

Cornelia Handl 1 collaboration

Jasmin Emmenegger 1 collaboration

Jan Eckmann 1 collaboration

Nicolas Frances 1 collaboration

Daniel Hunziker 1 collaboration

Daniela Krummenacher 1 collaboration

Dominik Rüttinger 1 collaboration

Alison Ribeiro 1 collaboration

Marina Bacac 1 collaboration

Alessandro Brigo 1 collaboration

David S Hewings 1 collaboration

Reinhard Dummer 1 collaboration

Mitchell P Levesque 1 collaboration

Gabriel Schnetzler 1 collaboration

Piergiorgio Pettazzoni 1 collaboration

Isabel D Burton 1 collaboration

Nicolle Thiemann-Freudenstein 1 collaboration

Sherri Dudal 1 collaboration

Caterina Bissantz 1 collaboration

Antonello Caruso 1 collaboration

Pascale David-Pierson 1 collaboration

Wouter Driessen 1 collaboration

Erich Koller 1 collaboration

Ben-Fillippo Krippendorff 1 collaboration

Martin Lechmann 1 collaboration

Andrés Olivares-Morales 1 collaboration

Axel Paehler 1 collaboration

Dietrich Türck 1 collaboration

Arthur Van De Vyver 1 collaboration

Ken Wang 1 collaboration

Lotte Winther 1 collaboration

Ulrike Obst-Sander 1 collaboration

Antonio Ricci 1 collaboration

Bernd Kuhn 1 collaboration

Andreas Kuglstatter 1 collaboration

David Hewings 1 collaboration

Annick Goergler 1 collaboration

Sandra Steiner 1 collaboration

Daniel Rueher 1 collaboration

Marie-Paule Imhoff 1 collaboration

Noemi Raschetti 1 collaboration

Hans-Peter Marty 1 collaboration

Aline Dietzig 1 collaboration

Andreas Ehler 1 collaboration

Dominique Burger 1 collaboration

William Pao 1 collaboration

Yvonne Alice Nagel 1 collaboration

Kenichi Umehara 1 collaboration

Tianyi Jiang 1 collaboration

Malika Ait-Goughoulte 1 collaboration

Neil Parrott 1 collaboration