Colleen M Niswender

Affiliations

Department of Pharmacology and Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, Tennessee, USA.
Vanderbilt Kennedy Center, Vanderbilt University, Nashville, Tennessee, USA.
Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee, USA.

Publications (65)

Profiling beneficial and potential adverse effects of MeCP2 overexpression in a hypomorphic Rett syndrome mouse model.

Genes, brain, and behavior

Avec: Sheryl Anne D Vermudez , Rocco G Gogliotti , Bright Arthur , Aditi Buch , Clarissa Morales , Yuta Moxley , Hemangi Rajpal , P Jeffrey Conn , Colleen M Niswender

Frontal cortex genetic ablation of metabotropic glutamate receptor subtype 3 (mGlu

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

Avec: Max E Joffe , Chiaki I Santiago , Sheryl Anne D Vermudez , Nicole M Fisher , Shalini Dogra , Colleen M Niswender , P Jeffrey Conn

Surveying heterocycles as amide bioisosteres within a series of mGlu

Bioorganic & medicinal chemistry letters

Avec: Carson W Reed , Jordan P Washecheck , Marc C Quitlag , Matthew T Jenkins , Alice L Rodriguez , Darren W Engers , Anna L Blobaum , P Jeffrey Conn , Colleen M Niswender , Craig W Lindsley

The discovery of VU0652957 (VU2957, Valiglurax): SAR and DMPK challenges en route to an mGlu

Bioorganic & medicinal chemistry letters

Avec: Joseph D Panarese , Darren W Engers , Yong-Jin Wu , Jason M Guernon , Aspen Chun , Alison R Gregro , Aaron M Bender , Rory A Capstick , Joshua M Wieting , Joanne J Bronson , John E Macor , Ryan Westphal , Matthew Soars , Julie E Engers , Andrew S Felts , Alice L Rodriguez , Kyle A Emmitte , Carrie K Jones , Anna L Blobaum , P Jeffrey Conn , Colleen M Niswender , Corey R Hopkins , Craig W Lindsley

Biased M

Science signaling

Avec: Sean P Moran , Zixiu Xiang , Catherine A Doyle , James Maksymetz , Xiaohui Lv , Sehr Faltin , Nicole M Fisher , Colleen M Niswender , Jerri M Rook , Craig W Lindsley , P Jeffrey Conn

Acute restraint stress redirects prefrontal cortex circuit function through mGlu

Neuron

Avec: Max E Joffe , James Maksymetz , Joseph R Luschinger , Shalini Dogra , Anthony S Ferranti , Deborah J Luessen , Isabel M Gallinger , Zixiu Xiang , Hannah Branthwaite , Patrick R Melugin , Kellie M Williford , Samuel W Centanni , Brenda C Shields , Craig W Lindsley , Erin S Calipari , Cody A Siciliano , Colleen M Niswender , Michael R Tadross , Danny G Winder , P Jeffrey Conn

Discovery of VU6007496: Challenges in the Development of an M

ACS chemical neuroscience

Avec: Julie L Engers , Katrina A Bollinger , Rory A Capstick , Madeline F Long , Aaron M Bender , Jonathan W Dickerson , Weimin Peng , Christopher C Presley , Hyekyung P Cho , Alice L Rodriguez , Colleen M Niswender , Sean P Moran , Zixiu Xiang , Anna L Blobaum , Olivier Boutaud , Jerri M Rook , Darren W Engers , P Jeffrey Conn , Craig W Lindsley

Development and profiling of mGlu

Bioorganic & medicinal chemistry letters

Avec: Carson W Reed , Alice L Rodriguez , Jacob J Kalbfleisch , Mabel Seto , Matthew T Jenkins , Anna L Blobaum , Sichen Chang , Craig W Lindsley , Colleen M Niswender

GRM7 gene mutations and consequences for neurodevelopment.

Pharmacology, biochemistry, and behavior

Avec: Geanne A Freitas , Colleen M Niswender

A Coordinated Attack: Rett Syndrome Therapeutic Development.

Trends in pharmacological sciences

Avec: Rocco G Gogliotti , Colleen M Niswender

Discovery, Structure-Activity Relationship, and Biological Characterization of a Novel Series of 6-((1 H-Pyrazolo[4,3- b]pyridin-3-yl)amino)-benzo[ d]isothiazole-3-carboxamides as Positive Allosteric Modulators of the Metabotropic Glutamate Receptor 4 (mGlu

Journal of medicinal chemistry

Avec: Sean R Bollinger , Darren W Engers , Joseph D Panarese , Mary West , Julie L Engers , Matthew T Loch , Alice L Rodriguez , Anna L Blobaum , Carrie K Jones , Analisa Thompson Gray , P Jeffrey Conn , Craig W Lindsley , Colleen M Niswender , Corey R Hopkins

Novel M

Bioorganic & medicinal chemistry letters

Avec: Michael S Poslusney , James M Salovich , Michael R Wood , Bruce J Melancon , Katrina A Bollinger , Vincent B Luscombe , Alice L Rodriguez , Darren W Engers , Thomas M Bridges , Colleen M Niswender , P Jeffrey Conn , Craig W Lindsley

mGlu

Cell reports

Avec: James Maksymetz , Nellie E Byun , Deborah J Luessen , Brianna Li , Robert L Barry , John C Gore , Colleen M Niswender , Craig W Lindsley , Max E Joffe , P Jeffrey Conn

Discovery of structurally distinct tricyclic M

Bioorganic & medicinal chemistry letters

Avec: Madeline F Long , Rory A Capstick , Paul K Spearing , Julie L Engers , Alison R Gregro , Sean R Bollinger , Sichen Chang , Vincent B Luscombe , Alice L Rodriguez , Hyekyung P Cho , Colleen M Niswender , Thomas M Bridges , P Jeffrey Conn , Craig W Lindsley , Darren W Engers , Kayla J Temple

Discovery and optimization of a novel CNS penetrant series of mGlu

Bioorganic & medicinal chemistry letters

Avec: Caitlin N Kent , Mark G Fulton , Kaylee J Stillwell , Jonathan W Dickerson , Matthew T Loch , Alice L Rodriguez , Anna L Blobaum , Olivier Boutaud , Jerri L Rook , Colleen M Niswender , P Jeffrey Conn , Craig W Lindsley

Regulation and functional consequences of mGlu

RNA (New York, N.Y.)

Avec: Christopher S Hofmann , Sheridan Carrington , Andrew N Keller , Karen J Gregory , Colleen M Niswender

mGlu

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

Avec: Deborah J Luessen , Isabel M Gallinger , Anthony S Ferranti , Daniel J Foster , Bruce J Melancon , Craig W Lindsley , Colleen M Niswender , P Jeffrey Conn

Exploration of group II metabotropic glutamate receptor modulation in mouse models of Rett syndrome and MECP2 Duplication syndrome.

Neuropharmacology

Avec: Sheryl Anne D Vermudez , Aditi Buch , Kelly Weiss , Rocco G Gogliotti , Colleen M Niswender

Novel pharmacological targets for GABAergic dysfunction in ADHD.

Neuropharmacology

Avec: Anthony S Ferranti , Deborah J Luessen , Colleen M Niswender

Development of a Selective and High Affinity Radioligand, [

Molecular pharmacology

Avec: Aidong Qi , Haley E Kling , Natasha Billard , Alice L Rodriguez , Li Peng , Jonathan W Dickerson , Julie L Engers , Aaron M Bender , Mark S Moehle , Craig W Lindsley , Jerri M Rook , Colleen M Niswender

Discovery of VU6016235: A Highly Selective, Orally Bioavailable, and Structurally Distinct Tricyclic M

ACS chemical neuroscience

Avec: Julie L Engers , Logan A Baker , Sichen Chang , Vincent B Luscombe , Alice L Rodriguez , Colleen M Niswender , Hyekyung P Cho , Michael Bubser , Analisa Thompson Gray , Carrie K Jones , Weimin Peng , Jerri M Rook , Thomas M Bridges , Olivier Boutaud , P Jeffrey Conn , Darren W Engers , Craig W Lindsley , Kayla J Temple

Phenotypic profiling of mGlu

Genes, brain, and behavior

Avec: Nicole M Fisher , Robert W Gould , Rocco G Gogliotti , Annalise J McDonald , Hana Badivuku , Susmita Chennareddy , Aditi B Buch , Annah M Moore , Matthew T Jenkins , W Hudson Robb , Craig W Lindsley , Carrie K Jones , P Jeffrey Conn , Colleen M Niswender

ACS pharmacology & translational science

Avec: Karen J Gregory , Thomas M Bridges , Rocco G Gogliotti , Shaun R Stauffer , Meredith J Noetzel , Carrie K Jones , Craig W Lindsley , P Jeffrey Conn , Colleen M Niswender

Discovery of a novel 2,3-dimethylimidazo[1,2-a]pyrazine-6-carboxamide M

Bioorganic & medicinal chemistry letters

Avec: Kayla J Temple , Julie L Engers , Madeline F Long , Katherine J Watson , Sichen Chang , Vincent B Luscombe , Matthew T Jenkins , Alice L Rodriguez , Colleen M Niswender , Thomas M Bridges , P Jeffrey Conn , Darren W Engers , Craig W Lindsley

Discovery of structurally distinct tricyclic M

Bioorganic & medicinal chemistry letters

Avec: Kayla J Temple , Madeline F Long , Julie L Engers , Katherine J Watson , Sichen Chang , Vincent B Luscombe , Alice L Rodriguez , Colleen M Niswender , Thomas M Bridges , P Jeffrey Conn , Darren W Engers , Craig W Lindsley

Discovery of a novel 3,4-dimethylcinnoline carboxamide M

Bioorganic & medicinal chemistry letters

Avec: Kayla J Temple , Julie L Engers , Madeline F Long , Alison R Gregro , Katherine J Watson , Sichen Chang , Matthew T Jenkins , Vincent B Luscombe , Alice L Rodriguez , Colleen M Niswender , Thomas M Bridges , P Jeffrey Conn , Darren W Engers , Craig W Lindsley

Further exploration of an N-aryl phenoxyethoxy pyridinone-based series of mGlu

Bioorganic & medicinal chemistry letters

Avec: Yosuke Yamada , Samantha E Yohn , Kristen Gilliland , Mathew T Loch , Michael L Schulte , Alice L Rodriguez , Anna L Blobaum , Colleen M Niswender , P Jeffrey Conn , Craig W Lindsley

Synthesis and characterization of chiral 6-azaspiro[2.5]octanes as potent and selective antagonists of the M

Bioorganic & medicinal chemistry letters

Avec: Aaron M Bender , Trever R Carter , Matthew Spock , Alice L Rodriguez , Jonathan W Dickerson , Jerri M Rook , Sichen Chang , Aidong Qi , Christopher C Presley , Darren W Engers , Joel M Harp , Thomas M Bridges , Colleen M Niswender , P Jeffrey Conn , Craig W Lindsley

A GRM7 mutation associated with developmental delay reduces mGlu7 expression and produces neurological phenotypes.

JCI insight

Avec: Nicole M Fisher , Aqeela AlHashim , Aditi B Buch , Hana Badivuku , Manar M Samman , Kelly M Weiss , Gabriela I Cestero , Mark D Does , Jerri M Rook , Craig W Lindsley , P Jeffrey Conn , Rocco G Gogliotti , Colleen M Niswender

Optimized Administration of the M

ACS chemical neuroscience

Avec: Jakub Cikowski , Calista Holt , Bright Arthur , Mackenzie Smith , Sonia Gonzalez , Craig W Lindsley , Colleen M Niswender , Rocco G Gogliotti

Discovery of a novel class of heteroaryl-pyrrolidinones as positive allosteric modulators of the muscarinic acetylcholine receptor M

Bioorganic & medicinal chemistry letters

Avec: Paul K Spearing , Hyekyung P Cho , Vincent B Luscombe , Anna L Blobaum , Olivier Boutaud , Darren W Engers , Alice L Rodriguez , Colleen M Niswender , P Jeffrey Conn , Craig W Lindsley , Aaron M Bender

Persistent challenges in the development of an mGlu

Bioorganic & medicinal chemistry letters

Avec: Jacob J Kalbfleisch , Alice L Rodriguez , Xia Lei , Kelly Weiss , Annie L Blobaum , Olivier Boutaud , Colleen M Niswender , Craig W Lindsley

Discovery of VU6008677: A Structurally Distinct Tricyclic M

ACS medicinal chemistry letters

Avec: Rory A Capstick , Sean R Bollinger , Julie L Engers , Madeline F Long , Sichen Chang , Vincent B Luscombe , Alice L Rodriguez , Colleen M Niswender , Thomas M Bridges , Olivier Boutaud , P Jeffrey Conn , Darren W Engers , Craig W Lindsley , Kayla J Temple

Elucidating the molecular logic of a metabotropic glutamate receptor heterodimer.

Nature communications

Avec: Xin Lin , Davide Provasi , Colleen M Niswender , Wesley B Asher , Jonathan A Javitch

Synthesis and pharmacological evaluation of bivalent tethered ligands to target the mGlu

Bioorganic & medicinal chemistry letters

Avec: Mark G Fulton , Matthew T Loch , Alice L Rodriguez , Xin Lin , Jonathan A Javitch , P Jeffrey Conn , Colleen M Niswender , Craig W Lindsley

VU6005806/AZN-00016130, an advanced M

Bioorganic & medicinal chemistry letters

Avec: Darren W Engers , Bruce J Melancon , Allison R Gregro , Jeanette L Bertron , Sean R Bollinger , Andrew S Felts , Leah C Konkol , Michael R Wood , Katrina A Bollinger , Vincent B Luscombe , Alice L Rodriguez , Carrie K Jones , Michael Bubser , Samantha E Yohn , Michael W Wood , Nicholas J Brandon , Mark E Dugan , Colleen M Niswender , P Jeffrey Conn , Thomas M Bridges , Craig W Lindsley

Discovery of VU2957 (Valiglurax): An mGlu

ACS medicinal chemistry letters

Avec: Joseph D Panarese , Darren W Engers , Yong-Jin Wu , Joanne J Bronson , John E Macor , Aspen Chun , Alice L Rodriguez , Andrew S Felts , Julie L Engers , Matthew T Loch , Kyle A Emmitte , Arlindo L Castelhano , Michael J Kates , Michael A Nader , Carrie K Jones , Anna L Blobaum , P Jeffrey Conn , Colleen M Niswender , Corey R Hopkins , Craig W Lindsley

SAR inspired by aldehyde oxidase (AO) metabolism: Discovery of novel, CNS penetrant tricyclic M

Bioorganic & medicinal chemistry letters

Avec: Trevor C Chopko , Changho Han , Alison R Gregro , Darren W Engers , Andrew S Felts , Mike S Poslusney , Katrina A Bollinger , Ryan D Morrison , Michael Bubser , Atin Lamsal , Vincent B Luscombe , Hyekyung P Cho , Nathalie C Schnetz-Boutaud , Alice L Rodriguez , Sichen Chang , J Scott Daniels , Donald F Stec , Colleen M Niswender , Carrie K Jones , Michael R Wood , Michael W Wood , Mark E Duggan , Nicholas J Brandon , P Jeffrey Conn , Thomas M Bridges , Craig W Lindsley , Bruce J Melancon

mGlu

ACS pharmacology & translational science

Avec: Zixiu Xiang , Xiaohui Lv , James Maksymetz , Branden J Stansley , Ayan Ghoshal , Rocco G Gogliotti , Colleen M Niswender , Craig W Lindsley , P Jeffrey Conn

Discovery of Novel Central Nervous System Penetrant Metabotropic Glutamate Receptor Subtype 2 (mGlu

Journal of medicinal chemistry

Avec: Elizabeth S Childress , Joshua M Wieting , Andrew S Felts , Megan M Breiner , Madeline F Long , Vincent B Luscombe , Alice L Rodriguez , Hyekyung P Cho , Anna L Blobaum , Colleen M Niswender , Kyle A Emmitte , P Jeffrey Conn , Craig W Lindsley

Input-specific regulation of glutamatergic synaptic transmission in the medial prefrontal cortex by mGlu

Science signaling

Avec: Zixiu Xiang , Xiaohui Lv , Xin Lin , Daniel E O'Brien , Molly K Altman , Craig W Lindsley , Jonathan A Javitch , Colleen M Niswender , P Jeffrey Conn

Discovery of the First Selective M

ACS pharmacology & translational science

Avec: Mark S Moehle , Aaron M Bender , Jonathan W Dickerson , Daniel J Foster , Aidong Qi , Hyekyung P Cho , Yuping Donsante , Weimin Peng , Zoey Bryant , Kaylee J Stillwell , Thomas M Bridges , Sichen Chang , Katherine J Watson , Jordan C O'Neill , Julie L Engers , Li Peng , Alice L Rodriguez , Colleen M Niswender , Craig W Lindsley , Ellen J Hess , P Jeffrey Conn , Jerri M Rook

Clinical and Preclinical Evidence for M

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

Avec: Mackenzie Smith , Bright Arthur , Jakub Cikowski , Calista Holt , Sonia Gonzalez , Nicole M Fisher , Sheryl Anne D Vermudez , Craig W Lindsley , Colleen M Niswender , Rocco G Gogliotti

Differential activity of mGlu

The Journal of biological chemistry

Avec: Xin Lin , Nicole M Fisher , Shalini Dogra , Rebecca K Senter , Carson W Reed , Jacob J Kalbfleisch , Craig W Lindsley , Wesley B Asher , Zixiu Xiang , Colleen M Niswender , Jonathan A Javitch

Discovery of a potent M

Bioorganic & medicinal chemistry letters

Avec: Rory A Capstick , David Whomble , Douglas L Orsi , Andrew S Felts , Alice L Rodriguez , Paige N Vinson , Sichen Chang , Anna L Blobaum , Colleen M Niswender , P Jeffrey Conn , Carrie K Jones , Craig W Lindsley , Changho Han

Differential Activity of Orthosteric Agonists and Allosteric Modulators at Metabotropic Glutamate Receptor 7.

Molecular pharmacology

Avec: Xia Lei , Christopher S Hofmann , Alice L Rodriguez , Colleen M Niswender

Discovery of "Molecular Switches" within a Series of mGlu

ACS bio & med chem Au

Avec: Lisa Barbaro , Alice L Rodriguez , Ashlyn N Blevins , Jonathan W Dickerson , Natasha Billard , Olivier Boutaud , Jerri L Rook , Colleen M Niswender , P Jeffrey Conn , Darren W Engers , Craig W Lindsley

Development of VU6036864: A Triazolopyridine-Based High-Quality Antagonist Tool Compound of the M

Journal of medicinal chemistry

Avec: Jinming Li , Douglas L Orsi , Julie L Engers , Madeline F Long , Rory A Capstick , Mallory A Maurer , Christopher C Presley , Paige N Vinson , Alice L Rodriguez , Allie Han , Hyekyung P Cho , Sichen Chang , Megan Jackson , Michael Bubser , Anna L Blobaum , Olivier Boutaud , Michael A Nader , Colleen M Niswender , P Jeffrey Conn , Carrie K Jones , Craig W Lindsley , Changho Han

Challenges in the Discovery and Optimization of mGlu

Letters in drug design & discovery

Avec: Mark Gallant Fulton , Matthew Thomas Loch , Caroline Anne Cuoco , Alice Lambert Rodriguez , Emily Days , Paige Newton Vinson , Krystian Andrezej Kozek , Charles David Weaver , Anna Louise Blobaum , Peter Jeffrey Conn , Colleen Marie Niswender , Craig William Lindsley

Synthesis and SAR of a series of mGlu

Bioorganic & medicinal chemistry letters

Avec: Jacob J Kalbfleisch , Carson W Reed , Charlotte Park , Paul K Spearing , Marc C Quitalig , Matthew T Jenkins , Alice L Rodriguez , Anna L Blobaum , P Jeffrey Conn , Colleen M Niswender , Craig W Lindsley

Evaluation of Synthetic Cytochrome P

ACS omega

Avec: Christopher C Presley , Charles K Perry , Elizabeth S Childress , Matthew J Mulder , Vincent B Luscombe , Alice L Rodriguez , Colleen M Niswender , P Jeffrey Conn , Craig W Lindsley

Discovery of an Orally Bioavailable and Central Nervous System (CNS) Penetrant mGlu

Journal of medicinal chemistry

Avec: Carson W Reed , Samantha E Yohn , Jordan P Washecheck , Hanna F Roenfanz , Marc C Quitalig , Vincent B Luscombe , Matthew T Jenkins , Alice L Rodriguez , Darren W Engers , Anna L Blobaum , P Jeffrey Conn , Colleen M Niswender , Craig W Lindsley

Discovery of 4-alkoxy-6-methylpicolinamide negative allosteric modulators of metabotropic glutamate receptor subtype 5.

Bioorganic & medicinal chemistry letters

Avec: Andrew S Felts , Katrina A Bollinger , Christopher J Brassard , Alice L Rodriguez , Ryan D Morrison , J Scott Daniels , Anna L Blobaum , Colleen M Niswender , Carrie K Jones , P Jeffrey Conn , Kyle A Emmitte , Craig W Lindsley

Discovery of Tricyclic Triazolo- and Imidazopyridine Lactams as M

ACS chemical neuroscience

Avec: Julie L Engers , Aaron M Bender , Jacob J Kalbfleisch , Hyekyung P Cho , Kaelyn S Lingenfelter , Vincent B Luscombe , Changho Han , Bruce J Melancon , Anna L Blobaum , Jonathan W Dickerson , Jerri M Rook , Colleen M Niswender , Kyle A Emmitte , P Jeffrey Conn , Craig W Lindsley

Activating mGlu

Biological psychiatry

Avec: Shalini Dogra , Branden J Stansley , Zixiu Xiang , Weilun Qian , Rocco G Gogliotti , Ferdinando Nicoletti , Craig W Lindsley , Colleen M Niswender , Max E Joffe , P Jeffrey Conn

Positive allosteric modulators (PAMs) of the group II metabotropic glutamate receptors: Design, synthesis, and evaluation as ex-vivo tool compounds.

Bioorganic & medicinal chemistry letters

Avec: Yousuke Yamada , Kristen Gilliland , Zixiu Xiang , Daniel Haymer , Katherine E Crocker , Matthew T Loch , Michael L Schulte , Alice L Rodriguez , Colleen M Niswender , P Jeffrey Conn , Craig W Lindsley , Bruce J Melancon

Lead optimization of the VU0486321 series of mGlu

Bioorganic & medicinal chemistry letters

Avec: Dexter C Davis , Joseph D Bungard , Sichen Chang , Alice L Rodriguez , Annie L Blobaum , Olivier Boutaud , Bruce J Melancon , Colleen M Niswender , P Jeffrey Conn , Craig W Lindsley

Discovery of VU6027459: A First-in-Class Selective and CNS Penetrant mGlu

ACS medicinal chemistry letters

Avec: Carson W Reed , Jacob J Kalbfleisch , Madison J Wong , Jordan P Washecheck , Ashton Hunter , Alice L Rodriguez , Anna L Blobaum , P Jeffrey Conn , Colleen M Niswender , Craig W Lindsley

Discovery of VU6028418: A Highly Selective and Orally Bioavailable M

ACS medicinal chemistry letters

Avec: Matthew Spock , Trever R Carter , Katrina A Bollinger , Changho Han , Logan A Baker , Alice L Rodriguez , Li Peng , Jonathan W Dickerson , Aidong Qi , Jerri M Rook , Jordan C O'Neill , Katherine J Watson , Sichen Chang , Thomas M Bridges , Julie L Engers , Darren W Engers , Colleen M Niswender , P Jeffrey Conn , Craig W Lindsley , Aaron M Bender

Development of

Journal of medicinal chemistry

Avec: Aaron T Garrison , Douglas L Orsi , Rory A Capstick , David Whomble , Jinming Li , Trever R Carter , Andrew S Felts , Paige N Vinson , Alice L Rodriguez , Allie Han , Krishma Hajari , Hyekyung P Cho , Laura B Teal , Madeline G Ragland , Masoud Ghamari-Langroudi , Michael Bubser , Sichen Chang , Nathalie C Schnetz-Boutaud , Olivier Boutaud , Anna L Blobaum , Daniel J Foster , Colleen M Niswender , P Jeffrey Conn , Craig W Lindsley , Carrie K Jones , Changho Han

Activation of metabotropic glutamate receptor 3 modulates thalamo-accumbal transmission and rescues schizophrenia-like physiological and behavioral deficits.

Biological psychiatry

Avec: Shalini Dogra , Caleb Aguayo , Zixiu Xiang , Jason Putnam , Joshua Smith , Curran Johnston , Daniel J Foster , Craig W Lindsley , Colleen M Niswender , P Jeffrey Conn

Discovery of a potent M

Bioorganic & medicinal chemistry letters

Avec: Douglas L Orsi , Andrew S Felts , Alice L Rodriguez , Paige N Vinson , Hyekyung P Cho , Sichen Chang , Anna L Blobaum , Colleen M Niswender , P Jeffrey Conn , Carrie K Jones , Craig W Lindsley , Changho Han

Therapeutic Potential for Metabotropic Glutamate Receptor 7 (mGlu

Molecular pharmacology

Avec: Harrison H Parent , Colleen M Niswender

MeCP2 gene therapy ameliorates disease phenotype in mouse model for Pitt Hopkins syndrome.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

Avec: Cassandra N Dennys , Sheryl Anne D Vermudez , Robert J M Deacon , J Andrea Sierra-Delgado , Kelly Rich , Xiaojin Zhang , Aditi Buch , Kelly Weiss , Yuta Moxley , Hemangi Rajpal , Francisca D Espinoza , Samantha Powers , Ariel S Ávila , Rocco G Gogliotti , Patricia Cogram , Colleen M Niswender , Kathrin C Meyer

Potentiation of the muscarinic acetylcholine receptor 1 modulates neurophysiological features in a mouse model of Rett syndrome.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

Avec: Hong-Wei Dong , Kelly Weiss , Kathryn Baugh , Mac J Meadows , Colleen M Niswender , Jeffrey L Neul

Réseau de co-auteurs

Craig W Lindsley 52 collaborations

P Jeffrey Conn 48 collaborations

Alice L Rodriguez 38 collaborations

Darren W Engers 19 collaborations

Anna L Blobaum 19 collaborations

Sichen Chang 16 collaborations

Julie L Engers 14 collaborations

Vincent B Luscombe 14 collaborations

Carrie K Jones 13 collaborations

Thomas M Bridges 13 collaborations

Rocco G Gogliotti 11 collaborations

Hyekyung P Cho 11 collaborations

Olivier Boutaud 10 collaborations

Andrew S Felts 9 collaborations

Zixiu Xiang 9 collaborations

Jerri M Rook 9 collaborations

Aaron M Bender 8 collaborations

Madeline F Long 8 collaborations

Jonathan W Dickerson 8 collaborations

Matthew T Jenkins 7 collaborations

Rory A Capstick 7 collaborations

Bruce J Melancon 7 collaborations

Changho Han 7 collaborations

Nicole M Fisher 6 collaborations

Carson W Reed 6 collaborations

Katrina A Bollinger 6 collaborations

Jacob J Kalbfleisch 6 collaborations

Kayla J Temple 6 collaborations

Sheryl Anne D Vermudez 5 collaborations

Shalini Dogra 5 collaborations

Kyle A Emmitte 5 collaborations

Matthew T Loch 5 collaborations

Michael Bubser 5 collaborations

Katherine J Watson 5 collaborations

Max E Joffe 4 collaborations

Alison R Gregro 4 collaborations

James Maksymetz 4 collaborations

Deborah J Luessen 4 collaborations

Christopher C Presley 4 collaborations

Sean R Bollinger 4 collaborations

Daniel J Foster 4 collaborations

Kelly Weiss 4 collaborations

Aidong Qi 4 collaborations

Xin Lin 4 collaborations

Jonathan A Javitch 4 collaborations

Douglas L Orsi 4 collaborations

Paige N Vinson 4 collaborations

Bright Arthur 3 collaborations

Aditi Buch 3 collaborations

Jordan P Washecheck 3 collaborations

Joseph D Panarese 3 collaborations

Corey R Hopkins 3 collaborations

Xiaohui Lv 3 collaborations

Anthony S Ferranti 3 collaborations

Weimin Peng 3 collaborations

Michael R Wood 3 collaborations

Paul K Spearing 3 collaborations

Li Peng 3 collaborations

Samantha E Yohn 3 collaborations

Trever R Carter 3 collaborations

Yuta Moxley 2 collaborations

Hemangi Rajpal 2 collaborations

Yong-Jin Wu 2 collaborations

Aspen Chun 2 collaborations

Joshua M Wieting 2 collaborations

Joanne J Bronson 2 collaborations

John E Macor 2 collaborations

Sean P Moran 2 collaborations

Isabel M Gallinger 2 collaborations

Analisa Thompson Gray 2 collaborations

Mark G Fulton 2 collaborations

Kaylee J Stillwell 2 collaborations

Jerri L Rook 2 collaborations

Christopher S Hofmann 2 collaborations

Karen J Gregory 2 collaborations

Natasha Billard 2 collaborations

Mark S Moehle 2 collaborations

Logan A Baker 2 collaborations

Hana Badivuku 2 collaborations

Aditi B Buch 2 collaborations

Kristen Gilliland 2 collaborations

Michael L Schulte 2 collaborations

Matthew Spock 2 collaborations

Jakub Cikowski 2 collaborations

Calista Holt 2 collaborations

Mackenzie Smith 2 collaborations

Sonia Gonzalez 2 collaborations

Xia Lei 2 collaborations

Annie L Blobaum 2 collaborations

Wesley B Asher 2 collaborations

Michael W Wood 2 collaborations

Nicholas J Brandon 2 collaborations

Michael A Nader 2 collaborations

Ryan D Morrison 2 collaborations

Nathalie C Schnetz-Boutaud 2 collaborations

J Scott Daniels 2 collaborations

Branden J Stansley 2 collaborations

Elizabeth S Childress 2 collaborations

Jordan C O'Neill 2 collaborations

David Whomble 2 collaborations

Jinming Li 2 collaborations

Allie Han 2 collaborations

Marc C Quitalig 2 collaborations

Clarissa Morales 1 collaboration

Chiaki I Santiago 1 collaboration

Marc C Quitlag 1 collaboration

Jason M Guernon 1 collaboration

Ryan Westphal 1 collaboration

Matthew Soars 1 collaboration

Julie E Engers 1 collaboration

Catherine A Doyle 1 collaboration

Sehr Faltin 1 collaboration

Joseph R Luschinger 1 collaboration

Hannah Branthwaite 1 collaboration

Patrick R Melugin 1 collaboration

Kellie M Williford 1 collaboration

Samuel W Centanni 1 collaboration

Brenda C Shields 1 collaboration

Erin S Calipari 1 collaboration

Cody A Siciliano 1 collaboration

Michael R Tadross 1 collaboration

Danny G Winder 1 collaboration

Mabel Seto 1 collaboration

Geanne A Freitas 1 collaboration

Mary West 1 collaboration

Michael S Poslusney 1 collaboration

James M Salovich 1 collaboration

Nellie E Byun 1 collaboration

Brianna Li 1 collaboration

Robert L Barry 1 collaboration

John C Gore 1 collaboration

Caitlin N Kent 1 collaboration

Sheridan Carrington 1 collaboration

Andrew N Keller 1 collaboration

Haley E Kling 1 collaboration

Robert W Gould 1 collaboration

Annalise J McDonald 1 collaboration

Susmita Chennareddy 1 collaboration

Annah M Moore 1 collaboration

W Hudson Robb 1 collaboration

Shaun R Stauffer 1 collaboration

Meredith J Noetzel 1 collaboration

Yosuke Yamada 1 collaboration

Mathew T Loch 1 collaboration

Joel M Harp 1 collaboration

Aqeela AlHashim 1 collaboration

Manar M Samman 1 collaboration

Kelly M Weiss 1 collaboration

Gabriela I Cestero 1 collaboration

Mark D Does 1 collaboration

Davide Provasi 1 collaboration

Allison R Gregro 1 collaboration

Jeanette L Bertron 1 collaboration

Leah C Konkol 1 collaboration

Mark E Dugan 1 collaboration

Arlindo L Castelhano 1 collaboration

Michael J Kates 1 collaboration

Trevor C Chopko 1 collaboration

Mike S Poslusney 1 collaboration

Atin Lamsal 1 collaboration

Donald F Stec 1 collaboration

Mark E Duggan 1 collaboration

Ayan Ghoshal 1 collaboration

Megan M Breiner 1 collaboration

Daniel E O'Brien 1 collaboration

Molly K Altman 1 collaboration

Yuping Donsante 1 collaboration

Zoey Bryant 1 collaboration

Ellen J Hess 1 collaboration

Rebecca K Senter 1 collaboration

Lisa Barbaro 1 collaboration

Ashlyn N Blevins 1 collaboration

Mallory A Maurer 1 collaboration

Megan Jackson 1 collaboration

Mark Gallant Fulton 1 collaboration

Matthew Thomas Loch 1 collaboration

Caroline Anne Cuoco 1 collaboration

Alice Lambert Rodriguez 1 collaboration

Emily Days 1 collaboration

Paige Newton Vinson 1 collaboration

Krystian Andrezej Kozek 1 collaboration

Charles David Weaver 1 collaboration

Anna Louise Blobaum 1 collaboration

Peter Jeffrey Conn 1 collaboration

Colleen Marie Niswender 1 collaboration

Craig William Lindsley 1 collaboration

Charlotte Park 1 collaboration

Charles K Perry 1 collaboration

Matthew J Mulder 1 collaboration

Hanna F Roenfanz 1 collaboration

Christopher J Brassard 1 collaboration

Kaelyn S Lingenfelter 1 collaboration

Weilun Qian 1 collaboration

Ferdinando Nicoletti 1 collaboration

Yousuke Yamada 1 collaboration

Daniel Haymer 1 collaboration

Katherine E Crocker 1 collaboration

Dexter C Davis 1 collaboration

Joseph D Bungard 1 collaboration

Madison J Wong 1 collaboration

Ashton Hunter 1 collaboration

Aaron T Garrison 1 collaboration

Krishma Hajari 1 collaboration

Laura B Teal 1 collaboration

Madeline G Ragland 1 collaboration

Masoud Ghamari-Langroudi 1 collaboration

Caleb Aguayo 1 collaboration

Jason Putnam 1 collaboration

Joshua Smith 1 collaboration

Curran Johnston 1 collaboration

Harrison H Parent 1 collaboration

Cassandra N Dennys 1 collaboration

Robert J M Deacon 1 collaboration

J Andrea Sierra-Delgado 1 collaboration

Kelly Rich 1 collaboration

Xiaojin Zhang 1 collaboration

Francisca D Espinoza 1 collaboration

Samantha Powers 1 collaboration

Ariel S Ávila 1 collaboration

Patricia Cogram 1 collaboration

Kathrin C Meyer 1 collaboration

Hong-Wei Dong 1 collaboration

Kathryn Baugh 1 collaboration

Mac J Meadows 1 collaboration

Jeffrey L Neul 1 collaboration