Hedda Wardemann

Affiliations

Division of B Cell Immunology, German Cancer Research Center, Heidelberg, Germany.

ORCID: http://orcid.org/0000-0003-3921-5933

Publications (27)

ALDH4A1 is an atherosclerosis auto-antigen targeted by protective antibodies.

Nature

Avec: Cristina Lorenzo , Pilar Delgado , Christian E Busse , Alejandro Sanz-Bravo , Inmaculada Martos-Folgado , Elena Bonzon-Kulichenko , Alessia Ferrarini , Ileana B Gonzalez-Valdes , Sonia M Mur , Raquel Roldán-Montero , Diego Martinez-Lopez , Jose L Martin-Ventura , Jesús Vázquez , Hedda Wardemann , Almudena R Ramiro

MDA-LDL vaccination induces athero-protective germinal-center-derived antibody responses.

Cell reports

Avec: Inmaculada Martos-Folgado , Alberto Del Monte-Monge , Cristina Lorenzo , Christian E Busse , Pilar Delgado , Sonia M Mur , Laura Cobos-Figueroa , Joan C Escolà-Gil , Jose L Martín-Ventura , Hedda Wardemann , Almudena R Ramiro

Repertoire and Neutralizing Activity of Antibodies Against Hepatitis C Virus E2 Peptide in Patients With Spontaneous Resolution of Hepatitis C.

The Journal of infectious diseases

Avec: Anne Olbrich , Hedda Wardemann , Stephan Böhm , Karen Rother , Che C Colpitts , Florian Wrensch , Thomas F Baumert , Thomas Berg , Julia Benckert

Clonal evolution and TCR specificity of the human T

Science immunology

Avec: Ilka Wahl , Anna S Obraztsova , Julia Puchan , Rebecca Hundsdorfer , Sumana Chakravarty , B Kim Lee Sim , Stephen L Hoffman , Peter G Kremsner , Benjamin Mordmüller , Hedda Wardemann

Sterilizing immunity: Understanding COVID-19.

Immunity

Avec: Ilka Wahl , Hedda Wardemann

Progress in vaccine development for infectious diseases-a Keystone Symposia report.

Annals of the New York Academy of Sciences

Avec: Jennifer Cable , Barney S Graham , Richard A Koup , Robert A Seder , Katalin Karikó , Norbert Pardi , Dan H Barouch , Bhawna Sharma , Susanne Rauch , Raffael Nachbagauer , Mattias N E Forsell , Michael Schotsaert , Ali H Ellebedy , Karin Loré , Darrell J Irvine , Emily Pilkington , Siri Tahtinen , Elizabeth A Thompson , Yanis Feraoun , Neil P King , Kevin Saunders , Galit Alter , Syed M Moin , Kwinten Sliepen , Gunilla B Karlsson Hedestam , Hedda Wardemann , Bali Pulendran , Nicole A Doria-Rose , Wan-Ting He , Jennifer A Juno , Sila Ataca , Adam K Wheatley , Jason S McLellan , Laura M Walker , Julia Lederhofer , Lisa C Lindesmith , Holger Wille , Peter J Hotez , Linda-Gail Bekker

Affinity-independent memory B cell origin of the early antibody-secreting cell response in naive individuals upon SARS-CoV-2 vaccination.

Immunity

Avec: Zhe Li , Anna Obraztsova , Fuwei Shang , Opeyemi Ernest Oludada , Joshua Malapit , Katrin Busch , Monique van Straaten , Erec Stebbins , Rajagopal Murugan , Hedda Wardemann

Antibodies against Plasmodium falciparum malaria at the molecular level.

Nature reviews. Immunology

Avec: Jean-Philippe Julien , Hedda Wardemann

Differences in Self-Recognition between Secreted Antibody and Membrane-Bound B Cell Antigen Receptor.

Journal of immunology (Baltimore, Md. : 1950)

Avec: Joseena Iype , Moumita Datta , Ahmad Khadour , Rudolf Übelhart , Antonella Nicolò , Tim Rollenske , Marcus Dühren-von Minden , Hedda Wardemann , Palash C Maity , Hassan Jumaa

Human IgA binds a diverse array of commensal bacteria.

The Journal of experimental medicine

Avec: Delphine Sterlin , Jehane Fadlallah , Olivia Adams , Claire Fieschi , Christophe Parizot , Karim Dorgham , Asok Rajkumar , Gaëlle Autaa , Hela El-Kafsi , Jean-Luc Charuel , Catherine Juste , Friederike Jönsson , Thomas Candela , Hedda Wardemann , Alexandra Aubry , Carmen Capito , Hélène Brisson , Christophe Tresallet , Richard D Cummings , Martin Larsen , Hans Yssel , Stephan von Gunten , Guy Gorochov

Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs.

Nature medicine

Avec: Rajagopal Murugan , Stephen W Scally , Giulia Costa , Ghulam Mustafa , Elaine Thai , Tizian Decker , Alexandre Bosch , Katherine Prieto , Elena A Levashina , Jean-Philippe Julien , Hedda Wardemann

Molecular and functional properties of human Plasmodium falciparum CSP C-terminus antibodies.

EMBO molecular medicine

Avec: Opeyemi Ernest Oludada , Giulia Costa , Clare Burn Aschner , Anna S Obraztsova , Katherine Prieto , Caterina Canetta , Stephen L Hoffman , Peter G Kremsner , Benjamin Mordmüller , Rajagopal Murugan , Jean-Philippe Julien , Elena A Levashina , Hedda Wardemann

Glycosylated nanoparticle-based PfCSP vaccine confers long-lasting antibody responses and sterile protection in mouse malaria model.

NPJ vaccines

Avec: Julia Ludwig , Stephen W Scally , Giulia Costa , Sandro Hoffmann , Rajagopal Murugan , Jana Lossin , Katherine Prieto , Anna Obraztsova , Nina Lobeto , Blandine Franke-Fayard , Chris J Janse , Celia Lebas , Nicolas Collin , Spela Binter , Paul Kellam , Elena A Levashina , Hedda Wardemann , Jean-Philippe Julien

Proceedings of the National Academy of Sciences of the United States of America

Avec: Palash C Maity , Mayas Bilal , Marvyn T Koning , Marc Young , Cornelis A M van Bergen , Valerio Renna , Antonella Nicolò , Moumita Datta , Eva Gentner-Göbel , Rob S Barendse , Sebastiaan F Somers , Ruben A L de Groen , Joost S P Vermaat , Daniela Steinbrecher , Christof Schneider , Eugen Tausch , Tamara Bittolo , Riccardo Bomben , Andrea Nicola Mazzarello , Giovanni Del Poeta , Wilma G M Kroes , J Tom van Wezel , Katharina Imkeller , Christian E Busse , Massimo Degano , Tamam Bakchoul , Axel Ronald Schulz , Henrik Mei , Paolo Ghia , Konstantia Kotta , Kostas Stamatopoulos , Hedda Wardemann , Antonella Zucchetto , Nicholas Chiorazzi , Valter Gattei , Stephan Stilgenbauer , Hendrik Veelken , Hassan Jumaa

High-throughput single-cell sequencing of paired TCRα and TCRβ genes for the direct expression-cloning and functional analysis of murine T-cell receptors.

European journal of immunology

Avec: Julia Ludwig , Ann-Kathrin Huber , Ilka Bartsch , Christian E Busse , Hedda Wardemann

How to induce protective humoral immunity against Plasmodium falciparum circumsporozoite protein.

The Journal of experimental medicine

Avec: Ilka Wahl , Hedda Wardemann

An efficient single-cell based method for linking human T cell phenotype to T cell receptor sequence and specificity.

European journal of immunology

Avec: Ilka Wahl , Sandro Hoffmann , Rebecca Hundsdorfer , Julia Puchan , Stephen L Hoffman , Peter G Kremsner , Benjamin Mordmüller , Christian E Busse , Hedda Wardemann

Phagocytosis of Plasmodium falciparum ring-stage parasites predicts protection against malaria.

Nature communications

Avec: Fauzia K Musasia , Irene N Nkumama , Roland Frank , Victor Kipkemboi , Martin Schneider , Kennedy Mwai , Dennis O Odera , Micha Rosenkranz , Kristin Fürle , Domitila Kimani , James Tuju , Patricia Njuguna , Mainga Hamaluba , Melissa C Kapulu , Hedda Wardemann , Auteur inconnu , Faith H A Osier

High-density binding to Plasmodium falciparum circumsporozoite protein repeats by inhibitory antibody elicited in mouse with human immunoglobulin repertoire.

PLoS pathogens

Avec: Iga Kucharska , Špela Binter , Rajagopal Murugan , Stephen W Scally , Julia Ludwig , Katherine Prieto , Elaine Thai , Giulia Costa , Kan Li , Gillian Q Horn , Yevel Flores-Garcia , Alexandre Bosch , Taylor Sicard , John L Rubinstein , Fidel Zavala , S Moses Dennison , Georgia D Tomaras , Elena A Levashina , Paul Kellam , Hedda Wardemann , Jean-Philippe Julien

HIV-1 Envelope Recognition by Polyreactive and Cross-Reactive Intestinal B Cells.

Cell reports

Avec: Cyril Planchais , Ayrin Kök , Alexia Kanyavuz , Valérie Lorin , Timothée Bruel , Florence Guivel-Benhassine , Tim Rollenske , Julie Prigent , Thierry Hieu , Thierry Prazuck , Laurent Lefrou , Hedda Wardemann , Olivier Schwartz , Jordan D Dimitrov , Laurent Hocqueloux , Hugo Mouquet

N-methyl-D-aspartate receptor dysfunction by unmutated human antibodies against the NR1 subunit.

Annals of neurology

Avec: Nina Kerstin Wenke , Jakob Kreye , Ewa Andrzejak , Adriana van Casteren , Jonas Leubner , Manuela S Murgueitio , S Momsen Reincke , Christopher Secker , Lars Schmidl , Christian Geis , Frauke Ackermann , Marc Nikolaus , Craig C Garner , Hedda Wardemann , Gerhard Wolber , Harald Prüss

Expression Cloning of Antibodies from Single Human B Cells.

Methods in molecular biology (Clifton, N.J.)

Avec: Hedda Wardemann , Christian E Busse

High microbiota reactivity of adult human intestinal IgA requires somatic mutations.

The Journal of experimental medicine

Avec: Johanna Kabbert , Julia Benckert , Tim Rollenske , Thomas C A Hitch , Thomas Clavel , Vuk Cerovic , Hedda Wardemann , Oliver Pabst

A high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity.

The Journal of experimental medicine

Avec: Elaine Thai , Giulia Costa , Anna Weyrich , Rajagopal Murugan , David Oyen , Yevel Flores-Garcia , Katherine Prieto , Alexandre Bosch , Angelo Valleriani , Nicholas C Wu , Tossapol Pholcharee , Stephen W Scally , Ian A Wilson , Hedda Wardemann , Jean-Philippe Julien , Elena A Levashina

Parallelism of intestinal secretory IgA shapes functional microbial fitness.

Nature

Avec: Tim Rollenske , Sophie Burkhalter , Lukas Muerner , Stephan von Gunten , Jolanta Lukasiewicz , Hedda Wardemann , Andrew J Macpherson

From Multiplex Serology to Serolomics-A Novel Approach to the Antibody Response against the SARS-CoV-2 Proteome.

Viruses

Avec: Julia Butt , Rajagopal Murugan , Theresa Hippchen , Sylvia Olberg , Monique van Straaten , Hedda Wardemann , Erec Stebbins , Hans-Georg Kräusslich , Ralf Bartenschlager , Hermann Brenner , Vibor Laketa , Ben Schöttker , Barbara Müller , Uta Merle , Tim Waterboer

Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein.

Cell reports

Avec: Elaine Thai , Rajagopal Murugan , Špela Binter , Clare Burn Aschner , Katherine Prieto , Audrey Kassardjian , Anna S Obraztsova , Ryu Won Kang , Yevel Flores-Garcia , Shamika Mathis-Torres , Kan Li , Gillian Q Horn , Richard H C Huntwork , Judith M Bolscher , Marloes H C de Bruijni , Robert Sauerwein , S Moses Dennison , Georgia D Tomaras , Fidel Zavala , Paul Kellam , Hedda Wardemann , Jean-Philippe Julien

Réseau de co-auteurs

Rajagopal Murugan 8 collaborations

Jean-Philippe Julien 7 collaborations

Christian E Busse 6 collaborations

Katherine Prieto 6 collaborations

Giulia Costa 5 collaborations

Elena A Levashina 5 collaborations

Ilka Wahl 4 collaborations

Tim Rollenske 4 collaborations

Stephen W Scally 4 collaborations

Elaine Thai 4 collaborations

Anna S Obraztsova 3 collaborations

Stephen L Hoffman 3 collaborations

Peter G Kremsner 3 collaborations

Benjamin Mordmüller 3 collaborations

Alexandre Bosch 3 collaborations

Julia Ludwig 3 collaborations

Paul Kellam 3 collaborations

Yevel Flores-Garcia 3 collaborations

Cristina Lorenzo 2 collaborations

Pilar Delgado 2 collaborations

Inmaculada Martos-Folgado 2 collaborations

Sonia M Mur 2 collaborations

Almudena R Ramiro 2 collaborations

Julia Benckert 2 collaborations

Julia Puchan 2 collaborations

Rebecca Hundsdorfer 2 collaborations

Anna Obraztsova 2 collaborations

Opeyemi Ernest Oludada 2 collaborations

Monique van Straaten 2 collaborations

Erec Stebbins 2 collaborations

Moumita Datta 2 collaborations

Antonella Nicolò 2 collaborations

Palash C Maity 2 collaborations

Hassan Jumaa 2 collaborations

Stephan von Gunten 2 collaborations

Clare Burn Aschner 2 collaborations

Sandro Hoffmann 2 collaborations

Špela Binter 2 collaborations

Kan Li 2 collaborations

Gillian Q Horn 2 collaborations

Fidel Zavala 2 collaborations

S Moses Dennison 2 collaborations

Georgia D Tomaras 2 collaborations

Alejandro Sanz-Bravo 1 collaboration

Elena Bonzon-Kulichenko 1 collaboration

Alessia Ferrarini 1 collaboration

Ileana B Gonzalez-Valdes 1 collaboration

Raquel Roldán-Montero 1 collaboration

Diego Martinez-Lopez 1 collaboration

Jose L Martin-Ventura 1 collaboration

Jesús Vázquez 1 collaboration

Alberto Del Monte-Monge 1 collaboration

Laura Cobos-Figueroa 1 collaboration

Joan C Escolà-Gil 1 collaboration

Jose L Martín-Ventura 1 collaboration

Anne Olbrich 1 collaboration

Stephan Böhm 1 collaboration

Karen Rother 1 collaboration

Che C Colpitts 1 collaboration

Florian Wrensch 1 collaboration

Thomas F Baumert 1 collaboration

Thomas Berg 1 collaboration

Sumana Chakravarty 1 collaboration

B Kim Lee Sim 1 collaboration

Jennifer Cable 1 collaboration

Barney S Graham 1 collaboration

Richard A Koup 1 collaboration

Robert A Seder 1 collaboration

Katalin Karikó 1 collaboration

Norbert Pardi 1 collaboration

Dan H Barouch 1 collaboration

Bhawna Sharma 1 collaboration

Susanne Rauch 1 collaboration

Raffael Nachbagauer 1 collaboration

Mattias N E Forsell 1 collaboration

Michael Schotsaert 1 collaboration

Ali H Ellebedy 1 collaboration

Karin Loré 1 collaboration

Darrell J Irvine 1 collaboration

Emily Pilkington 1 collaboration

Siri Tahtinen 1 collaboration

Elizabeth A Thompson 1 collaboration

Yanis Feraoun 1 collaboration

Neil P King 1 collaboration

Kevin Saunders 1 collaboration

Galit Alter 1 collaboration

Syed M Moin 1 collaboration

Kwinten Sliepen 1 collaboration

Gunilla B Karlsson Hedestam 1 collaboration

Bali Pulendran 1 collaboration

Nicole A Doria-Rose 1 collaboration

Wan-Ting He 1 collaboration

Jennifer A Juno 1 collaboration

Sila Ataca 1 collaboration

Adam K Wheatley 1 collaboration

Jason S McLellan 1 collaboration

Laura M Walker 1 collaboration

Julia Lederhofer 1 collaboration

Lisa C Lindesmith 1 collaboration

Holger Wille 1 collaboration

Peter J Hotez 1 collaboration

Linda-Gail Bekker 1 collaboration

Zhe Li 1 collaboration

Fuwei Shang 1 collaboration

Joshua Malapit 1 collaboration

Katrin Busch 1 collaboration

Joseena Iype 1 collaboration

Ahmad Khadour 1 collaboration

Rudolf Übelhart 1 collaboration

Marcus Dühren-von Minden 1 collaboration

Delphine Sterlin 1 collaboration

Jehane Fadlallah 1 collaboration

Olivia Adams 1 collaboration

Claire Fieschi 1 collaboration

Christophe Parizot 1 collaboration

Karim Dorgham 1 collaboration

Asok Rajkumar 1 collaboration

Gaëlle Autaa 1 collaboration

Hela El-Kafsi 1 collaboration

Jean-Luc Charuel 1 collaboration

Catherine Juste 1 collaboration

Friederike Jönsson 1 collaboration

Thomas Candela 1 collaboration

Alexandra Aubry 1 collaboration

Carmen Capito 1 collaboration

Hélène Brisson 1 collaboration

Christophe Tresallet 1 collaboration

Richard D Cummings 1 collaboration

Martin Larsen 1 collaboration

Hans Yssel 1 collaboration

Guy Gorochov 1 collaboration

Ghulam Mustafa 1 collaboration

Tizian Decker 1 collaboration

Caterina Canetta 1 collaboration

Jana Lossin 1 collaboration

Nina Lobeto 1 collaboration

Blandine Franke-Fayard 1 collaboration

Chris J Janse 1 collaboration

Celia Lebas 1 collaboration

Nicolas Collin 1 collaboration

Spela Binter 1 collaboration

Mayas Bilal 1 collaboration

Marvyn T Koning 1 collaboration

Marc Young 1 collaboration

Cornelis A M van Bergen 1 collaboration

Valerio Renna 1 collaboration

Eva Gentner-Göbel 1 collaboration

Rob S Barendse 1 collaboration

Sebastiaan F Somers 1 collaboration

Ruben A L de Groen 1 collaboration

Joost S P Vermaat 1 collaboration

Daniela Steinbrecher 1 collaboration

Christof Schneider 1 collaboration

Eugen Tausch 1 collaboration

Tamara Bittolo 1 collaboration

Riccardo Bomben 1 collaboration

Andrea Nicola Mazzarello 1 collaboration

Giovanni Del Poeta 1 collaboration

Wilma G M Kroes 1 collaboration

J Tom van Wezel 1 collaboration

Katharina Imkeller 1 collaboration

Massimo Degano 1 collaboration

Tamam Bakchoul 1 collaboration

Axel Ronald Schulz 1 collaboration

Henrik Mei 1 collaboration

Paolo Ghia 1 collaboration

Konstantia Kotta 1 collaboration

Kostas Stamatopoulos 1 collaboration

Antonella Zucchetto 1 collaboration

Nicholas Chiorazzi 1 collaboration

Valter Gattei 1 collaboration

Stephan Stilgenbauer 1 collaboration

Hendrik Veelken 1 collaboration

Ann-Kathrin Huber 1 collaboration

Ilka Bartsch 1 collaboration

Fauzia K Musasia 1 collaboration

Irene N Nkumama 1 collaboration

Roland Frank 1 collaboration

Victor Kipkemboi 1 collaboration

Martin Schneider 1 collaboration

Kennedy Mwai 1 collaboration

Dennis O Odera 1 collaboration

Micha Rosenkranz 1 collaboration

Kristin Fürle 1 collaboration

Domitila Kimani 1 collaboration

James Tuju 1 collaboration

Patricia Njuguna 1 collaboration

Mainga Hamaluba 1 collaboration

Melissa C Kapulu 1 collaboration

None None 1 collaboration

Faith H A Osier 1 collaboration

Iga Kucharska 1 collaboration

Taylor Sicard 1 collaboration

John L Rubinstein 1 collaboration

Cyril Planchais 1 collaboration

Ayrin Kök 1 collaboration

Alexia Kanyavuz 1 collaboration

Valérie Lorin 1 collaboration

Timothée Bruel 1 collaboration

Florence Guivel-Benhassine 1 collaboration

Julie Prigent 1 collaboration

Thierry Hieu 1 collaboration

Thierry Prazuck 1 collaboration

Laurent Lefrou 1 collaboration

Olivier Schwartz 1 collaboration

Jordan D Dimitrov 1 collaboration

Laurent Hocqueloux 1 collaboration

Hugo Mouquet 1 collaboration

Nina Kerstin Wenke 1 collaboration

Jakob Kreye 1 collaboration

Ewa Andrzejak 1 collaboration

Adriana van Casteren 1 collaboration

Jonas Leubner 1 collaboration

Manuela S Murgueitio 1 collaboration

S Momsen Reincke 1 collaboration

Christopher Secker 1 collaboration

Lars Schmidl 1 collaboration

Christian Geis 1 collaboration

Frauke Ackermann 1 collaboration

Marc Nikolaus 1 collaboration

Craig C Garner 1 collaboration

Gerhard Wolber 1 collaboration

Harald Prüss 1 collaboration

Johanna Kabbert 1 collaboration

Thomas C A Hitch 1 collaboration

Thomas Clavel 1 collaboration

Vuk Cerovic 1 collaboration

Oliver Pabst 1 collaboration

Anna Weyrich 1 collaboration

David Oyen 1 collaboration

Angelo Valleriani 1 collaboration

Nicholas C Wu 1 collaboration

Tossapol Pholcharee 1 collaboration

Ian A Wilson 1 collaboration

Sophie Burkhalter 1 collaboration

Lukas Muerner 1 collaboration

Jolanta Lukasiewicz 1 collaboration

Andrew J Macpherson 1 collaboration

Julia Butt 1 collaboration

Theresa Hippchen 1 collaboration

Sylvia Olberg 1 collaboration

Hans-Georg Kräusslich 1 collaboration

Ralf Bartenschlager 1 collaboration

Hermann Brenner 1 collaboration

Vibor Laketa 1 collaboration

Ben Schöttker 1 collaboration

Barbara Müller 1 collaboration

Uta Merle 1 collaboration

Tim Waterboer 1 collaboration

Audrey Kassardjian 1 collaboration

Ryu Won Kang 1 collaboration

Shamika Mathis-Torres 1 collaboration

Richard H C Huntwork 1 collaboration

Judith M Bolscher 1 collaboration

Marloes H C de Bruijni 1 collaboration

Robert Sauerwein 1 collaboration