Kevin Struhl

Affiliations

Dept. Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, United states of America.

ORCID: 0000-0002-4181-7856

Publications (23)

MafB, WDR77, and ß-catenin interact with each other and have similar genome association profiles.

PloS one

Avec: Lizhi He , Mingshi Gao , Henry Pratt , Zhiping Weng , Kevin Struhl

Condition-specific 3' mRNA isoform half-lives and stability elements in yeast.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Joseph V Geisberg , Zarmik Moqtaderi , Kevin Struhl

Chromatin regulates alternative polyadenylation via the RNA polymerase II elongation rate.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Joseph V Geisberg , Zarmik Moqtaderi , Kevin Struhl

S100A8/S100A9 cytokine acts as a transcriptional coactivator during breast cellular transformation.

Science advances

Avec: Ruisheng Song , Kevin Struhl

YAP and TAZ are transcriptional co-activators of AP-1 proteins and STAT3 during breast cellular transformation.

eLife

Avec: Lizhi He , Henry Pratt , Mingshi Gao , Fengxiang Wei , Zhiping Weng , Kevin Struhl

Nucleotide-level linkage of transcriptional elongation and polyadenylation.

eLife

Avec: Joseph V Geisberg , Zarmik Moqtaderi , Nova Fong , Benjamin Erickson , David L Bentley , Kevin Struhl

The distinction between epigenetics and epigenomics.

Trends in genetics : TIG

Avec: Kevin Struhl

A compensatory link between cleavage/polyadenylation and mRNA turnover regulates steady-state mRNA levels in yeast.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Zarmik Moqtaderi , Joseph V Geisberg , Kevin Struhl

Elongation rate of RNA polymerase II affects pausing patterns across 3' UTRs.

The Journal of biological chemistry

Avec: Alexandra Khitun , Christian Brion , Zarmik Moqtaderi , Joseph V Geisberg , L Stirling Churchman , Kevin Struhl

Non-canonical functions of enhancers: regulation of RNA polymerase III transcription, DNA replication, and V(D)J recombination.

Trends in genetics : TIG

Avec: Kevin Struhl

TRiC/CCT Chaperonin Governs RNA Polymerase II Activity in the Nucleus to Support RNA Homeostasis.

bioRxiv : the preprint server for biology

Avec: Zlata Gvozdenov , Audrey Yi Tyan Peng , Anusmita Biswas , Zeno Barcutean , Daniel Gestaut , Judith Frydman , Kevin Struhl , Brian C Freeman

Inflammatory regulatory network mediated by the joint action of NF-kB, STAT3, and AP-1 factors is involved in many human cancers.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Zhe Ji , Lizhi He , Aviv Regev , Kevin Struhl

Promoter-specific dynamics of TATA-binding protein association with the human genome.

Genome research

Avec: Yuko Hasegawa , Kevin Struhl

Lysine methyltransferase 2D regulates pancreatic carcinogenesis through metabolic reprogramming.

Gut

Avec: Marina Koutsioumpa , Maria Hatziapostolou , Christos Polytarchou , Ezequiel J Tolosa , Luciana L Almada , Swapna Mahurkar-Joshi , Jennifer Williams , Ana Belen Tirado-Rodriguez , Sara Huerta-Yepez , Dimitrios Karavias , Helen Kourea , George A Poultsides , Kevin Struhl , David W Dawson , Timothy R Donahue , Martín E Fernández-Zapico , Dimitrios Iliopoulos

The transcriptional elongation rate regulates alternative polyadenylation in yeast.

eLife

Avec: Joseph V Geisberg , Zarmik Moqtaderi , Kevin Struhl

Comparison of transcriptional initiation by RNA polymerase II across eukaryotic species.

eLife

Avec: Natalia Petrenko , Kevin Struhl

Pheno-RNA, a method to associate genes with a specific phenotype, identifies genes linked to cellular transformation.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Rabih Darwiche , Kevin Struhl

Requirements for RNA polymerase II preinitiation complex formation in vivo.

eLife

Avec: Natalia Petrenko , Yi Jin , Liguo Dong , Koon Ho Wong , Kevin Struhl

Different SP1 binding dynamics at individual genomic loci in human cells.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Yuko Hasegawa , Kevin Struhl

3' Untranslated Regions Are Modular Entities That Determine Polyadenylation Profiles.

Molecular and cellular biology

Avec: Kai Hin Lui , Joseph V Geisberg , Zarmik Moqtaderi , Kevin Struhl

Functional analysis of a random-sequence chromosome reveals a high level and the molecular nature of transcriptional noise in yeast cells.

Molecular cell

Avec: Zlata Gvozdenov , Zeno Barcutean , Kevin Struhl

How is polyadenylation restricted to 3'-untranslated regions?

Yeast (Chichester, England)

Avec: Kevin Struhl

Intrinsically disordered regions (IDRs): A vague and confusing concept for protein function.

Molecular cell

Avec: Kevin Struhl

Réseau de co-auteurs

Joseph V Geisberg 7 collaborations

Zarmik Moqtaderi 7 collaborations

Lizhi He 3 collaborations

Mingshi Gao 2 collaborations

Henry Pratt 2 collaborations

Zhiping Weng 2 collaborations

Zlata Gvozdenov 2 collaborations

Zeno Barcutean 2 collaborations

Yuko Hasegawa 2 collaborations

Natalia Petrenko 2 collaborations

Ruisheng Song 1 collaboration

Fengxiang Wei 1 collaboration

Nova Fong 1 collaboration

Benjamin Erickson 1 collaboration

David L Bentley 1 collaboration

Alexandra Khitun 1 collaboration

Christian Brion 1 collaboration

L Stirling Churchman 1 collaboration

Audrey Yi Tyan Peng 1 collaboration

Anusmita Biswas 1 collaboration

Daniel Gestaut 1 collaboration

Judith Frydman 1 collaboration

Brian C Freeman 1 collaboration

Zhe Ji 1 collaboration

Aviv Regev 1 collaboration

Marina Koutsioumpa 1 collaboration

Maria Hatziapostolou 1 collaboration

Christos Polytarchou 1 collaboration

Ezequiel J Tolosa 1 collaboration

Luciana L Almada 1 collaboration

Swapna Mahurkar-Joshi 1 collaboration

Jennifer Williams 1 collaboration

Ana Belen Tirado-Rodriguez 1 collaboration

Sara Huerta-Yepez 1 collaboration

Dimitrios Karavias 1 collaboration

Helen Kourea 1 collaboration

George A Poultsides 1 collaboration

David W Dawson 1 collaboration

Timothy R Donahue 1 collaboration

Martín E Fernández-Zapico 1 collaboration

Dimitrios Iliopoulos 1 collaboration

Rabih Darwiche 1 collaboration

Yi Jin 1 collaboration

Liguo Dong 1 collaboration

Koon Ho Wong 1 collaboration

Kai Hin Lui 1 collaboration