Laura Sandra Lello

Affiliations

Institute of Technology, University of Tartu, Tartu, Estonia.

Publications (11)

Cross-utilisation of template RNAs by alphavirus replicases.

PLoS pathogens

Avec: Laura Sandra Lello , Age Utt , Koen Bartholomeeusen , Sainan Wang , Kai Rausalu , Catherine Kendall , Sandra Coppens , Rennos Fragkoudis , Andrew Tuplin , Luke Alphey , Kevin K Ariën , Andres Merits

Synergistic Interferon-Alpha-Based Combinations for Treatment of SARS-CoV-2 and Other Viral Infections.

Viruses

Avec: Aleksandr Ianevski , Rouan Yao , Eva Zusinaite , Laura Sandra Lello , Sainan Wang , Eunji Jo , Jaewon Yang , Erlend Ravlo , Wei Wang , Hilde Lysvand , Kirsti Løseth , Valentyn Oksenych , Tanel Tenson , Marc P Windisch , Minna M Poranen , Anni I Nieminen , Svein Arne Nordbø , Mona Høysæter Fenstad , Gunnveig Grødeland , Pål Aukrust , Marius Trøseid , Anu Kantele , Eglė Lastauskienė , Astra Vitkauskienė , Nicolas Legrand , Andres Merits , Magnar Bjørås , Denis E Kainov

Activity, Template Preference, and Compatibility of Components of RNA Replicase of Eastern Equine Encephalitis Virus.

Journal of virology

Avec: Laura Sandra Lello , Agneta Miilimäe , Liubov Cherkashchenko , Ailar Omler , Rachel Skilton , Rachel Ireland , David Ulaeto , Andres Merits

LDL receptor in alphavirus entry: structural analysis and implications for antiviral therapy.

Nature communications

Avec: Ningning Wang , Andres Merits , Michael Veit , Laura Sandra Lello , Shuhan Kong , Houqi Jiao , Jie Chen , Yu Wang , Georgi Dobrikov , Félix A Rey , Shuo Su

Bortezomib inhibits chikungunya virus replication by interfering with viral protein synthesis.

PLoS neglected tropical diseases

Avec: Parveen Kaur , Laura Sandra Lello , Age Utt , Sujit Krishna Dutta , Andres Merits , Justin Jang Hann Chu

nsP4 Is a Major Determinant of Alphavirus Replicase Activity and Template Selectivity.

Journal of virology

Avec: Laura Sandra Lello , Koen Bartholomeeusen , Sainan Wang , Sandra Coppens , Rennos Fragkoudis , Luke Alphey , Kevin K Ariën , Andres Merits , Age Utt

A single-dose intranasal live-attenuated codon deoptimized vaccine provides broad protection against SARS-CoV-2 and its variants.

Nature communications

Avec: Xiang Liu , Wern Hann Ng , Eva Zusinaite , Joseph Freitas , Adam Taylor , Venugopal Yerragunta , Shukra Madhaha Aavula , Sambaiah Gorriparthi , Santhakumar Ponsekaran , Rama Lakshmi Bonda , Priyanka Mani , Sridevi V Nimmagadda , Sainan Wang , Laura Sandra Lello , Ali Zaid , Ujjwal Dua , Sharon A Taft-Benz , Elizabeth Anderson , Victoria K Baxter , Sanjay Sarkar , Zheng L Ling , Thomas M Ashhurst , Samuel M S Cheng , Priyabrata Pattnaik , Anand Kumar Kanakasapapathy , Ralph S Baric , Felicity J Burt , Malik Peiris , Mark T Heise , Nicholas J C King , Andres Merits , Rajendra Lingala , Suresh Mahalingam

A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 research.

PLoS biology

Avec: Suzannah J Rihn , Andres Merits , Siddharth Bakshi , Matthew L Turnbull , Arthur Wickenhagen , Akira J T Alexander , Carla Baillie , Benjamin Brennan , Fiona Brown , Kirstyn Brunker , Steven R Bryden , Kerry A Burness , Stephen Carmichael , Sarah J Cole , Vanessa M Cowton , Paul Davies , Chris Davis , Giuditta De Lorenzo , Claire L Donald , Mark Dorward , James I Dunlop , Matthew Elliott , Mazigh Fares , Ana da Silva Filipe , Joseph R Freitas , Wilhelm Furnon , Rommel J Gestuveo , Anna Geyer , Daniel Giesel , Daniel M Goldfarb , Nicola Goodman , Rory Gunson , C James Hastie , Vanessa Herder , Joseph Hughes , Clare Johnson , Natasha Johnson , Alain Kohl , Karen Kerr , Hannah Leech , Laura Sandra Lello , Kathy Li , Gauthier Lieber , Xiang Liu , Rajendra Lingala , Colin Loney , Daniel Mair , Marion J McElwee , Steven McFarlane , Jenna Nichols , Kyriaki Nomikou , Anne Orr , Richard J Orton , Massimo Palmarini , Yasmin A Parr , Rute Maria Pinto , Samantha Raggett , Elaine Reid , David L Robertson , Jamie Royle , Natalia Cameron-Ruiz , James G Shepherd , Katherine Smollett , Douglas G Stewart , Meredith Stewart , Elena Sugrue , Agnieszka M Szemiel , Aislynn Taggart , Emma C Thomson , Lily Tong , Leah S Torrie , Rachel Toth , Margus Varjak , Sainan Wang , Stuart G Wilkinson , Paul G Wyatt , Eva Zusinaite , Dario R Alessi , Arvind H Patel , Ali Zaid , Sam J Wilson , Suresh Mahalingam

Crystal structures of alphavirus nonstructural protein 4 (nsP4) reveal an intrinsically dynamic RNA-dependent RNA polymerase fold.

Nucleic acids research

Avec: Yaw Bia Tan , Laura Sandra Lello , Xin Liu , Yee-Song Law , Congbao Kang , Julien Lescar , Jie Zheng , Andres Merits , Dahai Luo

Bovine colostrum-derived antibodies against SARS-CoV-2 show great potential to serve as prophylactic agents.

PloS one

Avec: Kadri Kangro , Mihhail Kurašin , Kiira Gildemann , Eve Sankovski , Eva Žusinaite , Laura Sandra Lello , Raini Pert , Ants Kavak , Väino Poikalainen , Lembit Lepasalu , Marilin Kuusk , Robin Pau , Sander Piiskop , Siimu Rom , Ruth Oltjer , Kairi Tiirik , Karin Kogermann , Mario Plaas , Toomas Tiirats , Birgit Aasmäe , Mihkel Plaas , Karl Mumm , Dagni Krinka , Ene Talpsep , Meelis Kadaja , Joachim M Gerhold , Anu Planken , Andres Tover , Andres Merits , Andres Männik , Mart Ustav , Mart Ustav

4'-Fluorouridine inhibits alphavirus replication and infection

mBio

Avec: Peiqi Yin , Nicholas A May , Laura Sandra Lello , Atef Fayed , M Guston Parks , Adam M Drobish , Sainan Wang , Meghan Andrews , Zachary Sticher , Alexander A Kolykhalov , Michael G Natchus , George R Painter , Andres Merits , Margaret Kielian , Thomas E Morrison

Réseau de co-auteurs

Andres Merits 11 collaborations

Sainan Wang 6 collaborations

Age Utt 3 collaborations

Eva Zusinaite 3 collaborations

Koen Bartholomeeusen 2 collaborations

Sandra Coppens 2 collaborations

Rennos Fragkoudis 2 collaborations

Luke Alphey 2 collaborations

Kevin K Ariën 2 collaborations

Xiang Liu 2 collaborations

Ali Zaid 2 collaborations

Rajendra Lingala 2 collaborations

Suresh Mahalingam 2 collaborations

Mart Ustav 2 collaborations

Kai Rausalu 1 collaboration

Catherine Kendall 1 collaboration

Andrew Tuplin 1 collaboration

Aleksandr Ianevski 1 collaboration

Rouan Yao 1 collaboration

Eunji Jo 1 collaboration

Jaewon Yang 1 collaboration

Erlend Ravlo 1 collaboration

Wei Wang 1 collaboration

Hilde Lysvand 1 collaboration

Kirsti Løseth 1 collaboration

Valentyn Oksenych 1 collaboration

Tanel Tenson 1 collaboration

Marc P Windisch 1 collaboration

Minna M Poranen 1 collaboration

Anni I Nieminen 1 collaboration

Svein Arne Nordbø 1 collaboration

Mona Høysæter Fenstad 1 collaboration

Gunnveig Grødeland 1 collaboration

Pål Aukrust 1 collaboration

Marius Trøseid 1 collaboration

Anu Kantele 1 collaboration

Eglė Lastauskienė 1 collaboration

Astra Vitkauskienė 1 collaboration

Nicolas Legrand 1 collaboration

Magnar Bjørås 1 collaboration

Denis E Kainov 1 collaboration

Agneta Miilimäe 1 collaboration

Liubov Cherkashchenko 1 collaboration

Ailar Omler 1 collaboration

Rachel Skilton 1 collaboration

Rachel Ireland 1 collaboration

David Ulaeto 1 collaboration

Ningning Wang 1 collaboration

Michael Veit 1 collaboration

Shuhan Kong 1 collaboration

Houqi Jiao 1 collaboration

Jie Chen 1 collaboration

Yu Wang 1 collaboration

Georgi Dobrikov 1 collaboration

Félix A Rey 1 collaboration

Shuo Su 1 collaboration

Parveen Kaur 1 collaboration

Sujit Krishna Dutta 1 collaboration

Justin Jang Hann Chu 1 collaboration

Wern Hann Ng 1 collaboration

Joseph Freitas 1 collaboration

Adam Taylor 1 collaboration

Venugopal Yerragunta 1 collaboration

Shukra Madhaha Aavula 1 collaboration

Sambaiah Gorriparthi 1 collaboration

Santhakumar Ponsekaran 1 collaboration

Rama Lakshmi Bonda 1 collaboration

Priyanka Mani 1 collaboration

Sridevi V Nimmagadda 1 collaboration

Ujjwal Dua 1 collaboration

Sharon A Taft-Benz 1 collaboration

Elizabeth Anderson 1 collaboration

Victoria K Baxter 1 collaboration

Sanjay Sarkar 1 collaboration

Zheng L Ling 1 collaboration

Thomas M Ashhurst 1 collaboration

Samuel M S Cheng 1 collaboration

Priyabrata Pattnaik 1 collaboration

Anand Kumar Kanakasapapathy 1 collaboration

Ralph S Baric 1 collaboration

Felicity J Burt 1 collaboration

Malik Peiris 1 collaboration

Mark T Heise 1 collaboration

Nicholas J C King 1 collaboration

Suzannah J Rihn 1 collaboration

Siddharth Bakshi 1 collaboration

Matthew L Turnbull 1 collaboration

Arthur Wickenhagen 1 collaboration

Akira J T Alexander 1 collaboration

Carla Baillie 1 collaboration

Benjamin Brennan 1 collaboration

Fiona Brown 1 collaboration

Kirstyn Brunker 1 collaboration

Steven R Bryden 1 collaboration

Kerry A Burness 1 collaboration

Stephen Carmichael 1 collaboration

Sarah J Cole 1 collaboration

Vanessa M Cowton 1 collaboration

Paul Davies 1 collaboration

Chris Davis 1 collaboration

Giuditta De Lorenzo 1 collaboration

Claire L Donald 1 collaboration

Mark Dorward 1 collaboration

James I Dunlop 1 collaboration

Matthew Elliott 1 collaboration

Mazigh Fares 1 collaboration

Ana da Silva Filipe 1 collaboration

Joseph R Freitas 1 collaboration

Wilhelm Furnon 1 collaboration

Rommel J Gestuveo 1 collaboration

Anna Geyer 1 collaboration

Daniel Giesel 1 collaboration

Daniel M Goldfarb 1 collaboration

Nicola Goodman 1 collaboration

Rory Gunson 1 collaboration

C James Hastie 1 collaboration

Vanessa Herder 1 collaboration

Joseph Hughes 1 collaboration

Clare Johnson 1 collaboration

Natasha Johnson 1 collaboration

Alain Kohl 1 collaboration

Karen Kerr 1 collaboration

Hannah Leech 1 collaboration

Kathy Li 1 collaboration

Gauthier Lieber 1 collaboration

Colin Loney 1 collaboration

Daniel Mair 1 collaboration

Marion J McElwee 1 collaboration

Steven McFarlane 1 collaboration

Jenna Nichols 1 collaboration

Kyriaki Nomikou 1 collaboration

Anne Orr 1 collaboration

Richard J Orton 1 collaboration

Massimo Palmarini 1 collaboration

Yasmin A Parr 1 collaboration

Rute Maria Pinto 1 collaboration

Samantha Raggett 1 collaboration

Elaine Reid 1 collaboration

David L Robertson 1 collaboration

Jamie Royle 1 collaboration

Natalia Cameron-Ruiz 1 collaboration

James G Shepherd 1 collaboration

Katherine Smollett 1 collaboration

Douglas G Stewart 1 collaboration

Meredith Stewart 1 collaboration

Elena Sugrue 1 collaboration

Agnieszka M Szemiel 1 collaboration

Aislynn Taggart 1 collaboration

Emma C Thomson 1 collaboration

Lily Tong 1 collaboration

Leah S Torrie 1 collaboration

Rachel Toth 1 collaboration

Margus Varjak 1 collaboration

Stuart G Wilkinson 1 collaboration

Paul G Wyatt 1 collaboration

Dario R Alessi 1 collaboration

Arvind H Patel 1 collaboration

Sam J Wilson 1 collaboration

Yaw Bia Tan 1 collaboration

Xin Liu 1 collaboration

Yee-Song Law 1 collaboration

Congbao Kang 1 collaboration

Julien Lescar 1 collaboration

Jie Zheng 1 collaboration

Dahai Luo 1 collaboration

Kadri Kangro 1 collaboration

Mihhail Kurašin 1 collaboration

Kiira Gildemann 1 collaboration

Eve Sankovski 1 collaboration

Eva Žusinaite 1 collaboration

Raini Pert 1 collaboration

Ants Kavak 1 collaboration

Väino Poikalainen 1 collaboration

Lembit Lepasalu 1 collaboration

Marilin Kuusk 1 collaboration

Robin Pau 1 collaboration

Sander Piiskop 1 collaboration

Siimu Rom 1 collaboration

Ruth Oltjer 1 collaboration

Kairi Tiirik 1 collaboration

Karin Kogermann 1 collaboration

Mario Plaas 1 collaboration

Toomas Tiirats 1 collaboration

Birgit Aasmäe 1 collaboration

Mihkel Plaas 1 collaboration

Karl Mumm 1 collaboration

Dagni Krinka 1 collaboration

Ene Talpsep 1 collaboration

Meelis Kadaja 1 collaboration

Joachim M Gerhold 1 collaboration

Anu Planken 1 collaboration

Andres Tover 1 collaboration

Andres Männik 1 collaboration

Peiqi Yin 1 collaboration

Nicholas A May 1 collaboration

Atef Fayed 1 collaboration

M Guston Parks 1 collaboration

Adam M Drobish 1 collaboration

Meghan Andrews 1 collaboration

Zachary Sticher 1 collaboration

Alexander A Kolykhalov 1 collaboration

Michael G Natchus 1 collaboration

George R Painter 1 collaboration

Margaret Kielian 1 collaboration

Thomas E Morrison 1 collaboration