M Packer

Affiliations

School of Physics and Astronomy, University of Nottingham, Nottingham, NG7 2RD, UK.

Publications (31)

SGLT2 inhibitors in patients with heart failure with reduced ejection fraction: a meta-analysis of the EMPEROR-Reduced and DAPA-HF trials.

Lancet (London, England)

Avec: Faiez Zannad , João Pedro Ferreira , Stuart J Pocock , Stefan D Anker , Javed Butler , Gerasimos Filippatos , Martina Brueckmann , Anne Pernille Ofstad , Egon Pfarr , Waheed Jamal , Milton Packer

Angiotensin-Neprilysin Inhibition and Renal Outcomes in Heart Failure With Preserved Ejection Fraction.

Circulation

Avec: Finnian R Mc Causland , Martin P Lefkowitz , Brian Claggett , Nagesh S Anavekar , Michele Senni , Mauro Gori , Pardeep S Jhund , Martina M McGrath , Milton Packer , Victor Shi , Dirk J Van Veldhuisen , Faiez Zannad , Josep Comin-Colet , Marc A Pfeffer , John J V McMurray , Scott D Solomon

Serum potassium in the PARADIGM-HF trial.

European journal of heart failure

Avec: João Pedro Ferreira , Ulrik M Mogensen , Pardeep S Jhund , Akshay S Desai , Jean-Lucien Rouleau , Michael R Zile , Patrick Rossignol , Faiez Zannad , Milton Packer , Scott D Solomon , John J V McMurray

Guideline-directed medical therapy for heart failure does not exist: a non-judgmental framework for describing the level of adherence to evidence-based drug treatments for patients with a reduced ejection fraction.

European journal of heart failure

Avec: Milton Packer , Marco Metra

Liver function and prognosis, and influence of sacubitril/valsartan in patients with heart failure with reduced ejection fraction.

European journal of heart failure

Avec: Kota Suzuki , Brian Claggett , Masatoshi Minamisawa , Milton Packer , Michael R Zile , Jean Rouleau , Karl Swedberg , Martin Lefkowitz , Victor Shi , John J V McMurray , Stephen D Zucker , Scott D Solomon

Critical examination of mechanisms underlying the reduction in heart failure events with SGLT2 inhibitors: identification of a molecular link between their actions to stimulate erythrocytosis and to alleviate cellular stress.

Cardiovascular research

Avec: Milton Packer

Effects of Sacubitril-Valsartan Versus Valsartan in Women Compared With Men With Heart Failure and Preserved Ejection Fraction: Insights From PARAGON-HF.

Circulation

Avec: John J V McMurray , Alice M Jackson , Carolyn S P Lam , Margaret M Redfield , Inder S Anand , Junbo Ge , Marty P Lefkowitz , Aldo P Maggioni , Felipe Martinez , Milton Packer , Marc A Pfeffer , Burkert Pieske , Adel R Rizkala , Shalini V Sabarwal , Amil M Shah , Sanjiv J Shah , Victor C Shi , Dirk J van Veldhuisen , Faiez Zannad , Michael R Zile , Maja Cikes , Eva Goncalvesova , Tzvetana Katova , Anamaria Kosztin , Malgorzata Lelonek , Nancy Sweitzer , Orly Vardeny , Brian Claggett , Pardeep S Jhund , Scott D Solomon

Impact of Renal Impairment on Beta-Blocker Efficacy in Patients With Heart Failure.

Journal of the American College of Cardiology

Avec: Dipak Kotecha , Simrat K Gill , Marcus D Flather , Jane Holmes , Milton Packer , Giuseppe Rosano , Michael Böhm , John J V McMurray , John Wikstrand , Stefan D Anker , Dirk J van Veldhuisen , Luis Manzano , Thomas G von Lueder , Alan S Rigby , Bert Andersson , John Kjekshus , Hans Wedel , Frank Ruschitzka , John G F Cleland , Kevin Damman , Josep Redon , Andrew J S Coats , Auteur inconnu

Effects of Sacubitril/Valsartan on Biomarkers of Extracellular Matrix Regulation in Patients With HFrEF.

Journal of the American College of Cardiology

Avec: Michael R Zile , Eileen O'Meara , Brian Claggett , Margaret F Prescott , Scott D Solomon , Karl Swedberg , Milton Packer , John J V McMurray , Victor Shi , Martin Lefkowitz , Jean Rouleau

Income Inequality and Outcomes in Heart Failure: A Global Between-Country Analysis.

JACC. Heart failure

Avec: Pooja Dewan , Rasmus Rørth , Pardeep S Jhund , Joao Pedro Ferreira , Faiez Zannad , Li Shen , Lars Køber , William T Abraham , Akshay S Desai , Kenneth Dickstein , Milton Packer , Jean L Rouleau , Scott D Solomon , Karl Swedberg , Michael R Zile , John J V McMurray , Auteur inconnu

Reduced loop diuretic use in patients taking sacubitril/valsartan compared with enalapril: the PARADIGM-HF trial.

European journal of heart failure

Avec: Orly Vardeny , Brian Claggett , Jessica Kachadourian , Akshay S Desai , Milton Packer , Jean Rouleau , Michael R Zile , Karl Swedberg , Martin Lefkowitz , Victor Shi , John J V McMurray , Scott D Solomon

A Compelling Case for Less Aggressive Arrhythmia Management in Patients With Chronic Heart Failure and Long-Standing Atrial Fibrillation.

Journal of cardiac failure

Avec: Milton Packer

Epicardial Adipose Tissue Inflammation Can Cause the Distinctive Pattern of Cardiovascular Disorders Seen in Psoriasis.

The American journal of medicine

Avec: Milton Packer

Differential Impact of Heart Failure With Reduced Ejection Fraction on Men and Women.

Journal of the American College of Cardiology

Avec: Pooja Dewan , Rasmus Rørth , Pardeep S Jhund , Li Shen , Valeria Raparelli , Mark C Petrie , William T Abraham , Akshay S Desai , Kenneth Dickstein , Lars Køber , Ulrik M Mogensen , Milton Packer , Jean L Rouleau , Scott D Solomon , Karl Swedberg , Michael R Zile , John J V McMurray

The conundrum of patients with obesity, exercise intolerance, elevated ventricular filling pressures and a measured ejection fraction in the normal range.

European journal of heart failure

Avec: Milton Packer

Proportionate and Disproportionate Functional Mitral Regurgitation: A New Conceptual Framework That Reconciles the Results of the MITRA-FR and COAPT Trials.

JACC. Cardiovascular imaging

Avec: Paul A Grayburn , Anna Sannino , Milton Packer

Cardioprotective Effects of Sirtuin-1 and Its Downstream Effectors: Potential Role in Mediating the Heart Failure Benefits of SGLT2 (Sodium-Glucose Cotransporter 2) Inhibitors.

Circulation. Heart failure

Avec: Milton Packer

Cardiac and Kidney Benefits of Empagliflozin in Heart Failure Across the Spectrum of Kidney Function: Insights From EMPEROR-Reduced.

Circulation

Avec: Faiez Zannad , João Pedro Ferreira , Stuart J Pocock , Cordula Zeller , Stefan D Anker , Javed Butler , Gerasimos Filippatos , Sibylle Jenny Hauske , Martina Brueckmann , Egon Pfarr , Janet Schnee , Christoph Wanner , Milton Packer

Effect of Empagliflozin on the Clinical Stability of Patients With Heart Failure and a Reduced Ejection Fraction: The EMPEROR-Reduced Trial.

Circulation

Avec: Milton Packer , Stefan D Anker , Javed Butler , Gerasimos Filippatos , João Pedro Ferreira , Stuart J Pocock , Peter Carson , Inder Anand , Wolfram Doehner , Markus Haass , Michel Komajda , Alan Miller , Steen Pehrson , John R Teerlink , Martina Brueckmann , Waheed Jamal , Cordula Zeller , Sven Schnaidt , Faiez Zannad

A novel mechanism for the loss of mRNA activity in lipid nanoparticle delivery systems.

Nature communications

Avec: Meredith Packer , Dipendra Gyawali , Ravikiran Yerabolu , Joseph Schariter , Phil White

Effect of sacubitril/valsartan vs. enalapril on changes in heart failure therapies over time: the PARADIGM-HF trial.

European journal of heart failure

Avec: Ankeet S Bhatt , Muthiah Vaduganathan , Brian L Claggett , Jiankang Liu , Milton Packer , Akshay S Desai , Martin P Lefkowitz , Jean L Rouleau , Victor C Shi , Michael R Zile , Karl Swedberg , Orly Vardeny , John J V McMurray , Scott D Solomon

Influence of study discontinuation during the run-in period on the estimated efficacy of sacubitril/valsartan in the PARAGON-HF trial.

European journal of heart failure

Avec: Kota Suzuki , Brian Claggett , Masatoshi Minamisawa , Milton Packer , Michael R Zile , Marc A Pfeffer , Lu-May Chiang , Martin Lefkowitz , John J V McMurray , Scott D Solomon , Akshay S Desai

Effect of empagliflozin in patients with heart failure across the spectrum of left ventricular ejection fraction.

European heart journal

Avec: Javed Butler , Milton Packer , Gerasimos Filippatos , Joao Pedro Ferreira , Cordula Zeller , Janet Schnee , Martina Brueckmann , Stuart J Pocock , Faiez Zannad , Stefan D Anker

Effects of sacubitril/valsartan versus valsartan on renal function in patients with and without diabetes and heart failure with preserved ejection fraction: insights from PARAGON-HF.

European journal of heart failure

Avec: Alexander Peikert , Muthiah Vaduganathan , Finnian Mc Causland , Brian L Claggett , Safia Chatur , Milton Packer , Marc A Pfeffer , Faiez Zannad , Martin P Lefkowitz , Burkert Pieske , Hans-Dirk Düngen , John J V McMurray , Scott D Solomon

Early changes in estimated glomerular filtration rate post-initiation of empagliflozin in EMPEROR-Reduced.

European journal of heart failure

Avec: Faiez Zannad , João Pedro Ferreira , John Gregson , Bettina Johanna Kraus , Michaela Mattheus , Sibylle Jenny Hauske , Javed Butler , Gerasimos Filippatos , Christoph Wanner , Stefan D Anker , Stuart J Pocock , Milton Packer , Auteur inconnu

Bespoke magnetic field design for a magnetically shielded cold atom interferometer.

Scientific reports

Avec: P J Hobson , J Vovrosh , B Stray , M Packer , J Winch , N Holmes , F Hayati , K McGovern , R Bowtell , M J Brookes , K Bongs , T M Fromhold , M Holynski

Effect of sacubitril/valsartan on investigator-reported ventricular arrhythmias in PARADIGM-HF.

European journal of heart failure

Avec: James P Curtain , Alice M Jackson , Li Shen , Pardeep S Jhund , Kieran F Docherty , Mark C Petrie , Davide Castagno , Akshay S Desai , Luis E Rohde , Martin P Lefkowitz , Jean-Lucien Rouleau , Michael R Zile , Scott D Solomon , Karl Swedberg , Milton Packer , John J V McMurray

Weight change and clinical outcomes in heart failure with reduced ejection fraction: insights from EMPEROR-Reduced.

European journal of heart failure

Avec: Stefan D Anker , Muhammad Shahzeb Khan , Javed Butler , Anne Pernille Ofstad , Barbara Peil , Egon Pfarr , Wolfram Doehner , Naveed Sattar , Andrew J S Coats , Gerasimos Filippatos , João Pedro Ferreira , Faiez Zannad , Stuart Pocock , Milton Packer

Efficacy of a One-Piece Aberration Neutral Hydrophobic Acrylic Toric Intraocular Lens.

Clinical ophthalmology (Auckland, N.Z.)

Avec: Phillip J Buckhurst , George Lau , Jon I Williams , Mark Packer

Effect of empagliflozin on circulating proteomics in heart failure: mechanistic insights into the EMPEROR programme.

European heart journal

Avec: Faiez Zannad , João Pedro Ferreira , Javed Butler , Gerasimos Filippatos , James L Januzzi , Mikhail Sumin , Matthias Zwick , Maral Saadati , Stuart J Pocock , Naveed Sattar , Stefan D Anker , Milton Packer

Albiglutide in patients with type 2 diabetes and heart failure: a post-hoc analysis from Harmony Outcomes.

European journal of heart failure

Avec: João Pedro Ferreira , Abhinav Sharma , Francisco Vasques-Nóvoa , António Angélico-Gonçalves , Ana Rita Leite , Marta Borges-Canha , Davide Carvalho , Milton Packer , Faiez Zannad , Adelino Leite-Moreira , João Sérgio Neves

Réseau de co-auteurs

Milton Packer 28 collaborations

Faiez Zannad 13 collaborations

John J V McMurray 13 collaborations

Scott D Solomon 12 collaborations

Michael R Zile 10 collaborations

João Pedro Ferreira 8 collaborations

Stefan D Anker 8 collaborations

Javed Butler 7 collaborations

Gerasimos Filippatos 7 collaborations

Akshay S Desai 7 collaborations

Karl Swedberg 7 collaborations

Stuart J Pocock 6 collaborations

Brian Claggett 6 collaborations

Pardeep S Jhund 6 collaborations

Martina Brueckmann 4 collaborations

Martin P Lefkowitz 4 collaborations

Victor Shi 4 collaborations

Marc A Pfeffer 4 collaborations

Martin Lefkowitz 4 collaborations

Egon Pfarr 3 collaborations

Jean Rouleau 3 collaborations

Orly Vardeny 3 collaborations

None None 3 collaborations

Li Shen 3 collaborations

Jean L Rouleau 3 collaborations

Cordula Zeller 3 collaborations

Anne Pernille Ofstad 2 collaborations

Waheed Jamal 2 collaborations

Ulrik M Mogensen 2 collaborations

Jean-Lucien Rouleau 2 collaborations

Kota Suzuki 2 collaborations

Masatoshi Minamisawa 2 collaborations

Alice M Jackson 2 collaborations

Burkert Pieske 2 collaborations

Victor C Shi 2 collaborations

Dirk J van Veldhuisen 2 collaborations

Andrew J S Coats 2 collaborations

Pooja Dewan 2 collaborations

Rasmus Rørth 2 collaborations

Joao Pedro Ferreira 2 collaborations

Lars Køber 2 collaborations

William T Abraham 2 collaborations

Kenneth Dickstein 2 collaborations

Mark C Petrie 2 collaborations

Sibylle Jenny Hauske 2 collaborations

Janet Schnee 2 collaborations

Christoph Wanner 2 collaborations

Wolfram Doehner 2 collaborations

Muthiah Vaduganathan 2 collaborations

Brian L Claggett 2 collaborations

Naveed Sattar 2 collaborations

Finnian R Mc Causland 1 collaboration

Nagesh S Anavekar 1 collaboration

Michele Senni 1 collaboration

Mauro Gori 1 collaboration

Martina M McGrath 1 collaboration

Dirk J Van Veldhuisen 1 collaboration

Josep Comin-Colet 1 collaboration

Patrick Rossignol 1 collaboration

Marco Metra 1 collaboration

Stephen D Zucker 1 collaboration

Carolyn S P Lam 1 collaboration

Margaret M Redfield 1 collaboration

Inder S Anand 1 collaboration

Junbo Ge 1 collaboration

Marty P Lefkowitz 1 collaboration

Aldo P Maggioni 1 collaboration

Felipe Martinez 1 collaboration

Adel R Rizkala 1 collaboration

Shalini V Sabarwal 1 collaboration

Amil M Shah 1 collaboration

Sanjiv J Shah 1 collaboration

Maja Cikes 1 collaboration

Eva Goncalvesova 1 collaboration

Tzvetana Katova 1 collaboration

Anamaria Kosztin 1 collaboration

Malgorzata Lelonek 1 collaboration

Nancy Sweitzer 1 collaboration

Dipak Kotecha 1 collaboration

Simrat K Gill 1 collaboration

Marcus D Flather 1 collaboration

Jane Holmes 1 collaboration

Giuseppe Rosano 1 collaboration

Michael Böhm 1 collaboration

John Wikstrand 1 collaboration

Luis Manzano 1 collaboration

Thomas G von Lueder 1 collaboration

Alan S Rigby 1 collaboration

Bert Andersson 1 collaboration

John Kjekshus 1 collaboration

Hans Wedel 1 collaboration

Frank Ruschitzka 1 collaboration

John G F Cleland 1 collaboration

Kevin Damman 1 collaboration

Josep Redon 1 collaboration

Eileen O'Meara 1 collaboration

Margaret F Prescott 1 collaboration

Jessica Kachadourian 1 collaboration

Valeria Raparelli 1 collaboration

Paul A Grayburn 1 collaboration

Anna Sannino 1 collaboration

Peter Carson 1 collaboration

Inder Anand 1 collaboration

Markus Haass 1 collaboration

Michel Komajda 1 collaboration

Alan Miller 1 collaboration

Steen Pehrson 1 collaboration

John R Teerlink 1 collaboration

Sven Schnaidt 1 collaboration

Meredith Packer 1 collaboration

Dipendra Gyawali 1 collaboration

Ravikiran Yerabolu 1 collaboration

Joseph Schariter 1 collaboration

Phil White 1 collaboration

Ankeet S Bhatt 1 collaboration

Jiankang Liu 1 collaboration

Lu-May Chiang 1 collaboration

Alexander Peikert 1 collaboration

Finnian Mc Causland 1 collaboration

Safia Chatur 1 collaboration

Hans-Dirk Düngen 1 collaboration

John Gregson 1 collaboration

Bettina Johanna Kraus 1 collaboration

Michaela Mattheus 1 collaboration

P J Hobson 1 collaboration

J Vovrosh 1 collaboration

B Stray 1 collaboration

J Winch 1 collaboration

N Holmes 1 collaboration

F Hayati 1 collaboration

K McGovern 1 collaboration

R Bowtell 1 collaboration

M J Brookes 1 collaboration

K Bongs 1 collaboration

T M Fromhold 1 collaboration

M Holynski 1 collaboration

James P Curtain 1 collaboration

Kieran F Docherty 1 collaboration

Davide Castagno 1 collaboration

Luis E Rohde 1 collaboration

Muhammad Shahzeb Khan 1 collaboration

Barbara Peil 1 collaboration

Stuart Pocock 1 collaboration

Phillip J Buckhurst 1 collaboration

George Lau 1 collaboration

Jon I Williams 1 collaboration

Mark Packer 1 collaboration

James L Januzzi 1 collaboration

Mikhail Sumin 1 collaboration

Matthias Zwick 1 collaboration

Maral Saadati 1 collaboration

Abhinav Sharma 1 collaboration

Francisco Vasques-Nóvoa 1 collaboration

António Angélico-Gonçalves 1 collaboration

Ana Rita Leite 1 collaboration

Marta Borges-Canha 1 collaboration

Davide Carvalho 1 collaboration

Adelino Leite-Moreira 1 collaboration

João Sérgio Neves 1 collaboration