Matthew Spite

Affiliations

Center for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. mspite@bwh.harvard.edu.

ORCID: http://orcid.org/0000-0002-8868-3648

Publications (32)

Publisher Correction: Dynamic changes to lipid mediators support transitions among macrophage subtypes during muscle regeneration.

Nature immunology

Avec: Nikolas Giannakis , Brian E Sansbury , Andreas Patsalos , Tristan T Hays , Colin O Riley , Xianlin Han , Matthew Spite , Laszlo Nagy

Radiation-Induced Macrophage Senescence Impairs Resolution Programs and Drives Cardiovascular Inflammation.

Journal of immunology (Baltimore, Md. : 1950)

Avec: Sudeshna Sadhu , Christa Decker , Brian E Sansbury , Michael Marinello , Allison Seyfried , Jennifer Howard , Masayuki Mori , Zeinab Hosseini , Thilaka Arunachalam , Aloke V Finn , John M Lamar , David Jourd'heuil , Liang Guo , Katherine C MacNamara , Matthew Spite , Gabrielle Fredman

Dynamic changes to lipid mediators support transitions among macrophage subtypes during muscle regeneration.

Nature immunology

Avec: Nikolas Giannakis , Brian E Sansbury , Andreas Patsalos , Tristan T Hays , Colin O Riley , Xianlin Han , Matthew Spite , Laszlo Nagy

Resolvin D1 promotes the targeting and clearance of necroptotic cells.

Cell death and differentiation

Avec: Brennan D Gerlach , Michael Marinello , Justin Heinz , Nicholas Rymut , Brian E Sansbury , Colin O Riley , Sudeshna Sadhu , Zeinab Hosseini , Yoko Kojima , Dale D Tang , Nicholas J Leeper , Matthew Spite , Margarida Barroso , Katey J Rayner , Gabrielle Fredman

Fish Oil Increases Specialized Pro-resolving Lipid Mediators in PAD (The OMEGA-PAD II Trial).

The Journal of surgical research

Avec: Joel L Ramirez , Warren J Gasper , Sukaynah A Khetani , Greg J Zahner , Nancy K Hills , Pete T Mitchell , Brian E Sansbury , Michael S Conte , Matthew Spite , S Marlene Grenon

Resolving inflammation in nonalcoholic steatohepatitis.

The Journal of clinical investigation

Avec: Matthew Spite

The Resolvin D2-GPR18 Axis Enhances Bone Marrow Function and Limits Hepatic Fibrosis in Aging.

bioRxiv : the preprint server for biology

Avec: Hannah Fitzgerald , Jesse L Bonin , Sudeshna Sadhu , Masharh Lipscomb , Nirupam Biswas , Christa Decker , Melisande Nabage , Ramon Bossardi , Michael Marinello , Agustina Hebe Mena , Kurrim Gilliard , Matthew Spite , Alejandro Adam , Katherine C MacNamara , Gabrielle Fredman

PCTR1 Enhances Repair and Bacterial Clearance in Skin Wounds.

The American journal of pathology

Avec: Brian E Sansbury , Xiaofeng Li , Blenda Wong , Colin O Riley , Ashley E Shay , Robert Nshimiyimana , Nicos A Petasis , Charles N Serhan , Matthew Spite

12-Lipoxygenase Regulates Cold Adaptation and Glucose Metabolism by Producing the Omega-3 Lipid 12-HEPE from Brown Fat.

Cell metabolism

Avec: Luiz Osório Leiria , Chih-Hao Wang , Matthew D Lynes , Kunyan Yang , Farnaz Shamsi , Mari Sato , Satoru Sugimoto , Emily Y Chen , Valerie Bussberg , Niven R Narain , Brian E Sansbury , Justin Darcy , Tian Lian Huang , Sean D Kodani , Masaji Sakaguchi , Andréa L Rocha , Tim J Schulz , Alexander Bartelt , Gökhan S Hotamisligil , Michael F Hirshman , Klaus van Leyen , Laurie J Goodyear , Matthias Blüher , Aaron M Cypess , Michael A Kiebish , Matthew Spite , Yu-Hua Tseng

Obesity-linked suppression of membrane-bound

eLife

Avec: Robert N Helsley , Venkateshwari Varadharajan , Amanda L Brown , Anthony D Gromovsky , Rebecca C Schugar , Iyappan Ramachandiran , Kevin Fung , Mohammad Nasser Kabbany , Rakhee Banerjee , Chase K Neumann , Chelsea Finney , Preeti Pathak , Danny Orabi , Lucas J Osborn , William Massey , Renliang Zhang , Anagha Kadam , Brian E Sansbury , Calvin Pan , Jessica Sacks , Richard G Lee , Rosanne M Crooke , Mark J Graham , Madeleine E Lemieux , Valentin Gogonea , John P Kirwan , Daniela S Allende , Mete Civelek , Paul L Fox , Lawrence L Rudel , Aldons J Lusis , Matthew Spite , J Mark Brown

Netrin-1 Alters Adipose Tissue Macrophage Fate and Function in Obesity.

Immunometabolism

Avec: Monika Sharma , Martin Schlegel , Emily J Brown , Brian E Sansbury , Ada Weinstock , Milessa S Afonso , Emma M Corr , Coen van Solingen , Lianne C Shanley , Daniel Peled , Ravichandran Ramasamy , Ann Marie Schmidt , Matthew Spite , Edward A Fisher , Kathryn J Moore

Myeloid-Specific Deficiency of

Journal of immunology (Baltimore, Md. : 1950)

Avec: Andrew R Reeves , Brian E Sansbury , Meixia Pan , Xianlin Han , Matthew Spite , Andrew S Greenberg

Proresolving receptor tames inflammation in atherosclerosis.

The Journal of clinical investigation

Avec: Hebe Agustina Mena , Matthew Spite

Bioactive lipids and metabolic syndrome-a symposium report.

Annals of the New York Academy of Sciences

Avec: Loren M DeVito , Edward A Dennis , Barbara B Kahn , Gerald I Shulman , Joseph L Witztum , Sudeshna Sadhu , Joseph Nickels , Matthew Spite , Susan Smyth , Sarah Spiegel

Insights into the role of the resolvin D2-GPR18 signaling axis in cardiovascular physiology and disease.

Advances in pharmacology (San Diego, Calif.)

Avec: Matthew Spite , Gabrielle Fredman

Regulatory T Cells License Macrophage Pro-Resolving Functions During Atherosclerosis Regression.

Circulation research

Avec: Monika Sharma , Martin P Schlegel , Milessa S Afonso , Emily J Brown , Karishma Rahman , Ada Weinstock , Brian E Sansbury , Emma M Corr , Coen van Solingen , Graeme J Koelwyn , Lianne C Shanley , Lauren Beckett , Daniel Peled , Juan J Lafaille , Matthew Spite , P'ng Loke , Edward A Fisher , Kathryn J Moore

Resolvin D1 Enhances Necroptotic Cell Clearance Through Promoting Macrophage Fatty Acid Oxidation and Oxidative Phosphorylation.

Arteriosclerosis, thrombosis, and vascular biology

Avec: Zeinab Hosseini , Michael Marinello , Christa Decker , Brian E Sansbury , Sudeshna Sadhu , Brennan D Gerlach , Ramon Bossardi Ramos , Alejandro P Adam , Matthew Spite , Gabrielle Fredman

Brown adipose tissue-derived MaR2 contributes to cold-induced resolution of inflammation.

Nature metabolism

Avec: Satoru Sugimoto , Hebe Agustina Mena , Brian E Sansbury , Shio Kobayashi , Tadataka Tsuji , Chih-Hao Wang , Xuanzhi Yin , Tian Lian Huang , Joji Kusuyama , Sean D Kodani , Justin Darcy , Gerson Profeta , Nayara Pereira , Rudolph E Tanzi , Can Zhang , Thomas Serwold , Efi Kokkotou , Laurie J Goodyear , Aaron M Cypess , Luiz Osório Leiria , Matthew Spite , Yu-Hua Tseng

Resolvin D2-G-Protein Coupled Receptor 18 Enhances Bone Marrow Function and Limits Steatosis and Hepatic Collagen Accumulation in Aging.

The American journal of pathology

Avec: Hannah Fitzgerald , Jesse L Bonin , Sayeed Khan , Maya Eid , Sudeshna Sadhu , Allison Rahtes , Masharh Lipscomb , Nirupam Biswas , Christa Decker , Melisande Nabage , Ramon Bossardi Ramos , Giesse Albeche Duarte , Michael Marinello , Anne Chen , Hasan Basri Aydin , Hebe Agustina Mena , Kurrim Gilliard , Matthew Spite , C Michael DiPersio , Alejandro P Adam , Katherine C MacNamara , Gabrielle Fredman

Tissue factor targeting peptide enhances nanoparticle binding and delivery of a synthetic specialized pro-resolving lipid mediator to injured arteries.

JVS-vascular science

Avec: Elizabeth S Levy , Alexander S Kim , Evan Werlin , Mian Chen , Brian E Sansbury , Matthew Spite , Tejal A Desai , Michael S Conte

Brown adipose tissue activation in humans increases plasma levels of lipid mediators.

The Journal of clinical endocrinology and metabolism

Avec: Mary E Walker , Sean D Kodani , Hebe Agustina Mena , Yu-Hua Tseng , Aaron M Cypess , Matthew Spite

Resolvin D2-GPR18 Signaling on Myeloid Cells Limits Plaque Necrosis.

bioRxiv : the preprint server for biology

Avec: Masharh Lipscomb , Sean Walis , Michael Marinello , Hebe Agustina Mena , Matthew Spite , Gabrielle Fredman

Resolvin D1 promotes efferocytosis in aging by limiting senescent cell-induced MerTK cleavage.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Avec: Nicholas Rymut , Justin Heinz , Sudeshna Sadhu , Zeinab Hosseini , Colin O Riley , Michael Marinello , Jackson Maloney , Katherine C MacNamara , Matthew Spite , Gabrielle Fredman

Myeloid ALX/FPR2 regulates vascularization following tissue injury.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Brian E Sansbury , Xiaofeng Li , Blenda Wong , Andreas Patsalos , Nikolas Giannakis , Michael J Zhang , Laszlo Nagy , Matthew Spite

Platelet-conditioned media induces an anti-inflammatory macrophage phenotype through EP4.

Journal of thrombosis and haemostasis : JTH

Avec: Sean P Heffron , Ada Weinstock , Bianca Scolaro , Shiyu Chen , Brian E Sansbury , Greg Marecki , Christina C Rolling , Hanane El Bannoudi , Tessa Barrett , James W Canary , Matthew Spite , Jeffrey S Berger , Edward A Fisher

Wnt signaling enhances macrophage responses to IL-4 and promotes resolution of atherosclerosis.

eLife

Avec: Ada Weinstock , Karishma Rahman , Or Yaacov , Hitoo Nishi , Prashanthi Menon , Cyrus A Nikain , Michela L Garabedian , Stephanie Pena , Naveed Akbar , Brian E Sansbury , Sean P Heffron , Jianhua Liu , Gregory Marecki , Dawn Fernandez , Emily J Brown , Kelly V Ruggles , Stephen A Ramsey , Chiara Giannarelli , Matthew Spite , Robin P Choudhury , P'ng Loke , Edward A Fisher

Effect of stretching on inflammation in a subcutaneous carrageenan mouse model analyzed at single-cell resolution.

Journal of cellular physiology

Avec: Lisbeth Berrueta , Dennis Muñoz-Vergara , Daniel Martin , Rebecca Thompson , Brian E Sansbury , Matthew Spite , Gary J Badger , Helene M Langevin

Resolvin D2 limits atherosclerosis progression via myeloid cell-GPR18.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Avec: Masharh Lipscomb , Sean Walis , Michael Marinello , Hebe Agustina Mena , Katherine C MacNamara , Matthew Spite , Gabrielle Fredman

EGR2 is an epigenomic regulator of phagocytosis and antifungal immunity in alveolar macrophages.

JCI insight

Avec: Zsuzsanna Kolostyak , Dora Bojcsuk , Viktoria Baksa , Zsuzsa Mathene Szigeti , Krisztian Bene , Zsolt Czimmerer , Pal Boto , Lina Fadel , Szilard Poliska , Laszlo Halasz , Petros Tzerpos , Wilhelm K Berger , Andres Villabona-Rueda , Zsofia Varga , Tunde Kovacs , Andreas Patsalos , Attila Pap , György Vámosi , Peter Bai , Balazs Dezso , Matthew Spite , Franco R D'Alessio , Istvan Szatmari , Laszlo Nagy

Dynamic changes in proresolving lipid mediators and their receptors following acute vascular injury in male rats.

Physiological reports

Avec: Hideo Kagaya , Alexander S Kim , Mian Chen , Pei-Yu Lin , Xuanzhi Yin , Matthew Spite , Michael S Conte

Exercise-stimulated Resolvin Biosynthesis in Adipose Tissue is Abrogated by High Fat Diet-induced Adrenergic Deficiency.

bioRxiv : the preprint server for biology

Avec: Ernesto H Pena Calderin , Jing-Juan Zheng , Nolan L Boyd , Will Lynch , Brian E Sansbury , Matthew Spite , Bradford G Hill , Jason Hellmann

Improving Functional Muscle Regeneration in Volumetric Muscle Loss Injuries by Shifting the Balance of Inflammatory and Pro-Resolving Lipid Mediators.

bioRxiv : the preprint server for biology

Avec: Thomas C Turner , Frank S Pittman , Hongmanlin Zhang , Lauren A Hymel , Tianyi Zheng , Monica Behara , Shannon E Anderson , Julia Andraca Harrer , Kaitlyn A Link , Mashoor Al Ahammed , Kristal Maner-Smith , Xueyun Liu , Xuanzhi Yin , Hong S Lim , Matthew Spite , Peng Qiu , Andrés J García , Luke J Mortensen , Young C Jang , Nick J Willett , Edward A Botchwey

Réseau de co-auteurs

Brian E Sansbury 19 collaborations

Gabrielle Fredman 9 collaborations

Michael Marinello 8 collaborations

Sudeshna Sadhu 7 collaborations

Hebe Agustina Mena 6 collaborations

Colin O Riley 5 collaborations

Katherine C MacNamara 5 collaborations

Andreas Patsalos 4 collaborations

Laszlo Nagy 4 collaborations

Christa Decker 4 collaborations

Zeinab Hosseini 4 collaborations

Masharh Lipscomb 4 collaborations

Ada Weinstock 4 collaborations

Edward A Fisher 4 collaborations

Nikolas Giannakis 3 collaborations

Xianlin Han 3 collaborations

Michael S Conte 3 collaborations

Sean D Kodani 3 collaborations

Aaron M Cypess 3 collaborations

Yu-Hua Tseng 3 collaborations

Emily J Brown 3 collaborations

Xuanzhi Yin 3 collaborations

Tristan T Hays 2 collaborations

Brennan D Gerlach 2 collaborations

Justin Heinz 2 collaborations

Nicholas Rymut 2 collaborations

Hannah Fitzgerald 2 collaborations

Jesse L Bonin 2 collaborations

Nirupam Biswas 2 collaborations

Melisande Nabage 2 collaborations

Kurrim Gilliard 2 collaborations

Xiaofeng Li 2 collaborations

Blenda Wong 2 collaborations

Luiz Osório Leiria 2 collaborations

Chih-Hao Wang 2 collaborations

Satoru Sugimoto 2 collaborations

Justin Darcy 2 collaborations

Tian Lian Huang 2 collaborations

Laurie J Goodyear 2 collaborations

Monika Sharma 2 collaborations

Milessa S Afonso 2 collaborations

Emma M Corr 2 collaborations

Coen van Solingen 2 collaborations

Lianne C Shanley 2 collaborations

Daniel Peled 2 collaborations

Kathryn J Moore 2 collaborations

Karishma Rahman 2 collaborations

P'ng Loke 2 collaborations

Ramon Bossardi Ramos 2 collaborations

Alejandro P Adam 2 collaborations

Alexander S Kim 2 collaborations

Mian Chen 2 collaborations

Sean Walis 2 collaborations

Sean P Heffron 2 collaborations

Allison Seyfried 1 collaboration

Jennifer Howard 1 collaboration

Masayuki Mori 1 collaboration

Thilaka Arunachalam 1 collaboration

Aloke V Finn 1 collaboration

John M Lamar 1 collaboration

David Jourd'heuil 1 collaboration

Liang Guo 1 collaboration

Yoko Kojima 1 collaboration

Dale D Tang 1 collaboration

Nicholas J Leeper 1 collaboration

Margarida Barroso 1 collaboration

Katey J Rayner 1 collaboration

Joel L Ramirez 1 collaboration

Warren J Gasper 1 collaboration

Sukaynah A Khetani 1 collaboration

Greg J Zahner 1 collaboration

Nancy K Hills 1 collaboration

Pete T Mitchell 1 collaboration

S Marlene Grenon 1 collaboration

Ramon Bossardi 1 collaboration

Agustina Hebe Mena 1 collaboration

Alejandro Adam 1 collaboration

Ashley E Shay 1 collaboration

Robert Nshimiyimana 1 collaboration

Nicos A Petasis 1 collaboration

Charles N Serhan 1 collaboration

Matthew D Lynes 1 collaboration

Kunyan Yang 1 collaboration

Farnaz Shamsi 1 collaboration

Mari Sato 1 collaboration

Emily Y Chen 1 collaboration

Valerie Bussberg 1 collaboration

Niven R Narain 1 collaboration

Masaji Sakaguchi 1 collaboration

Andréa L Rocha 1 collaboration

Tim J Schulz 1 collaboration

Alexander Bartelt 1 collaboration

Gökhan S Hotamisligil 1 collaboration

Michael F Hirshman 1 collaboration

Klaus van Leyen 1 collaboration

Matthias Blüher 1 collaboration

Michael A Kiebish 1 collaboration

Robert N Helsley 1 collaboration

Venkateshwari Varadharajan 1 collaboration

Amanda L Brown 1 collaboration

Anthony D Gromovsky 1 collaboration

Rebecca C Schugar 1 collaboration

Iyappan Ramachandiran 1 collaboration

Kevin Fung 1 collaboration

Mohammad Nasser Kabbany 1 collaboration

Rakhee Banerjee 1 collaboration

Chase K Neumann 1 collaboration

Chelsea Finney 1 collaboration

Preeti Pathak 1 collaboration

Danny Orabi 1 collaboration

Lucas J Osborn 1 collaboration

William Massey 1 collaboration

Renliang Zhang 1 collaboration

Anagha Kadam 1 collaboration

Calvin Pan 1 collaboration

Jessica Sacks 1 collaboration

Richard G Lee 1 collaboration

Rosanne M Crooke 1 collaboration

Mark J Graham 1 collaboration

Madeleine E Lemieux 1 collaboration

Valentin Gogonea 1 collaboration

John P Kirwan 1 collaboration

Daniela S Allende 1 collaboration

Mete Civelek 1 collaboration

Paul L Fox 1 collaboration

Lawrence L Rudel 1 collaboration

Aldons J Lusis 1 collaboration

J Mark Brown 1 collaboration

Martin Schlegel 1 collaboration

Ravichandran Ramasamy 1 collaboration

Ann Marie Schmidt 1 collaboration

Andrew R Reeves 1 collaboration

Meixia Pan 1 collaboration

Andrew S Greenberg 1 collaboration

Loren M DeVito 1 collaboration

Edward A Dennis 1 collaboration

Barbara B Kahn 1 collaboration

Gerald I Shulman 1 collaboration

Joseph L Witztum 1 collaboration

Joseph Nickels 1 collaboration

Susan Smyth 1 collaboration

Sarah Spiegel 1 collaboration

Martin P Schlegel 1 collaboration

Graeme J Koelwyn 1 collaboration

Lauren Beckett 1 collaboration

Juan J Lafaille 1 collaboration

Shio Kobayashi 1 collaboration

Tadataka Tsuji 1 collaboration

Joji Kusuyama 1 collaboration

Gerson Profeta 1 collaboration

Nayara Pereira 1 collaboration

Rudolph E Tanzi 1 collaboration

Can Zhang 1 collaboration

Thomas Serwold 1 collaboration

Efi Kokkotou 1 collaboration

Sayeed Khan 1 collaboration

Maya Eid 1 collaboration

Allison Rahtes 1 collaboration

Giesse Albeche Duarte 1 collaboration

Anne Chen 1 collaboration

Hasan Basri Aydin 1 collaboration

C Michael DiPersio 1 collaboration

Elizabeth S Levy 1 collaboration

Evan Werlin 1 collaboration

Tejal A Desai 1 collaboration

Mary E Walker 1 collaboration

Jackson Maloney 1 collaboration

Michael J Zhang 1 collaboration

Bianca Scolaro 1 collaboration

Shiyu Chen 1 collaboration

Greg Marecki 1 collaboration

Christina C Rolling 1 collaboration

Hanane El Bannoudi 1 collaboration

Tessa Barrett 1 collaboration

James W Canary 1 collaboration

Jeffrey S Berger 1 collaboration

Or Yaacov 1 collaboration

Hitoo Nishi 1 collaboration

Prashanthi Menon 1 collaboration

Cyrus A Nikain 1 collaboration

Michela L Garabedian 1 collaboration

Stephanie Pena 1 collaboration

Naveed Akbar 1 collaboration

Jianhua Liu 1 collaboration

Gregory Marecki 1 collaboration

Dawn Fernandez 1 collaboration

Kelly V Ruggles 1 collaboration

Stephen A Ramsey 1 collaboration

Chiara Giannarelli 1 collaboration

Robin P Choudhury 1 collaboration

Lisbeth Berrueta 1 collaboration

Dennis Muñoz-Vergara 1 collaboration

Daniel Martin 1 collaboration

Rebecca Thompson 1 collaboration

Gary J Badger 1 collaboration

Helene M Langevin 1 collaboration

Zsuzsanna Kolostyak 1 collaboration

Dora Bojcsuk 1 collaboration

Viktoria Baksa 1 collaboration

Zsuzsa Mathene Szigeti 1 collaboration

Krisztian Bene 1 collaboration

Zsolt Czimmerer 1 collaboration

Pal Boto 1 collaboration

Lina Fadel 1 collaboration

Szilard Poliska 1 collaboration

Laszlo Halasz 1 collaboration

Petros Tzerpos 1 collaboration

Wilhelm K Berger 1 collaboration

Andres Villabona-Rueda 1 collaboration

Zsofia Varga 1 collaboration

Tunde Kovacs 1 collaboration

Attila Pap 1 collaboration

György Vámosi 1 collaboration

Peter Bai 1 collaboration

Balazs Dezso 1 collaboration

Franco R D'Alessio 1 collaboration

Istvan Szatmari 1 collaboration

Hideo Kagaya 1 collaboration

Pei-Yu Lin 1 collaboration

Ernesto H Pena Calderin 1 collaboration

Jing-Juan Zheng 1 collaboration

Nolan L Boyd 1 collaboration

Will Lynch 1 collaboration

Bradford G Hill 1 collaboration

Jason Hellmann 1 collaboration

Thomas C Turner 1 collaboration

Frank S Pittman 1 collaboration

Hongmanlin Zhang 1 collaboration

Lauren A Hymel 1 collaboration

Tianyi Zheng 1 collaboration

Monica Behara 1 collaboration

Shannon E Anderson 1 collaboration

Julia Andraca Harrer 1 collaboration

Kaitlyn A Link 1 collaboration

Mashoor Al Ahammed 1 collaboration

Kristal Maner-Smith 1 collaboration

Xueyun Liu 1 collaboration

Hong S Lim 1 collaboration

Peng Qiu 1 collaboration

Andrés J García 1 collaboration

Luke J Mortensen 1 collaboration

Young C Jang 1 collaboration

Nick J Willett 1 collaboration

Edward A Botchwey 1 collaboration