Megan Beetch

Affiliations

Food, Nutrition and Health Program, Faculty of Land and Food Systems, University of British Columbia, Vancouver, BC V6T 1Z4, Canada.

Publications (19)

Pterostilbene Changes Epigenetic Marks at Enhancer Regions of Oncogenes in Breast Cancer Cells.

Antioxidants (Basel, Switzerland)

Avec: Sadaf Harandi-Zadeh , Cayla Boycott , Megan Beetch , Tony Yang , Benjamin J E Martin , Kevin Ren , Anna Kwasniak , John H Dupuis , Katarzyna Lubecka , Rickey Y Yada , LeAnn J Howe , Barbara Stefanska

Reduction in O-GlcNAcylation Mitigates the Severity of Inflammatory Response in Cerulein-Induced Acute Pancreatitis in a Mouse Model.

Biology

Avec: Mackenzie Moore , Nandini Avula , Alicia Wong , Megan Beetch , Seokwon Jo , Emilyn U Alejandro

Targeted and selective knockout of the TLQP-21 neuropeptide unmasks its unique role in energy homeostasis.

Molecular metabolism

Avec: Bhavani S Sahu , Maria Razzoli , Seth McGonigle , Jean Pierre Pallais , Megin E Nguyen , Masato Sadahiro , Cheng Jiang , Wei-Jye Lin , Kevin A Kelley , Pedro Rodriguez , Rachel Mansk , Cheryl Cero , Giada Caviola , Paola Palanza , Loredana Rao , Megan Beetch , Emilyn Alejandro , Yuk Y Sham , Andrea Frontini , Stephen R Salton , Alessandro Bartolomucci

Stilbenoid-Mediated Epigenetic Activation of Semaphorin 3A in Breast Cancer Cells Involves Changes in Dynamic Interactions of DNA with DNMT3A and NF1C Transcription Factor.

Molecular nutrition & food research

Avec: Megan Beetch , Katarzyna Lubecka , Kate Shen , Kirsty Flower , Sadaf Harandi-Zadeh , Matthew Suderman , James M Flanagan , Barbara Stefanska

Author Correction: DNA methylation landscape of triple-negative ductal carcinoma in situ (DCIS) progressing to the invasive stage in canine breast cancer.

Scientific reports

Avec: Megan Beetch , Sadaf Harandi-Zadeh , Tony Yang , Cayla Boycott , Yihang Chen , Barbara Stefanska , Sulma I Mohammed

Pterostilbene leads to DNMT3B-mediated DNA methylation and silencing of OCT1-targeted oncogenes in breast cancer cells.

The Journal of nutritional biochemistry

Avec: Megan Beetch , Cayla Boycott , Sadaf Harandi-Zadeh , Tony Yang , Benjamin J E Martin , Thomas Dixon-McDougall , Kevin Ren , Allison Gacad , John H Dupuis , Melissa Ullmer , Katarzyna Lubecka , Rickey Y Yada , Carolyn J Brown , LeAnn J Howe , Barbara Stefanska

DNA hypermethylation of

Epigenetics

Avec: Kamil Ziarniak , Tony Yang , Cayla Boycott , Megan Beetch , Maciej Sassek , Emilia Grzeda , Yuexi Ma , Joanna H Sliwowska , Barbara Stefanska

DNA methylation landscape of triple-negative ductal carcinoma in situ (DCIS) progressing to the invasive stage in canine breast cancer.

Scientific reports

Avec: Megan Beetch , Sadaf Harandi-Zadeh , Tony Yang , Cayla Boycott , Yihang Chen , Barbara Stefanska , Sulma I Mohammed

Placental mTOR Signaling and Sexual Dimorphism in Metabolic Health across the Lifespan of Offspring.

Children (Basel, Switzerland)

Avec: Megan Beetch , Emilyn U Alejandro

O-linked N-acetylglucosamine transferase (OGT) regulates pancreatic α-cell function in mice.

The Journal of biological chemistry

Avec: Ahmad Essawy , Seokwon Jo , Megan Beetch , Amber Lockridge , Eric Gustafson , Emilyn U Alejandro

Placental Insulin Receptor Transiently Regulates Glucose Homeostasis in the Adult Mouse Offspring of Multiparous Dams.

Biomedicines

Avec: Grace Chung , Ramkumar Mohan , Megan Beetch , Seokwon Jo , Emilyn Uy Alejandro

Dietary antioxidants remodel DNA methylation patterns in chronic disease.

British journal of pharmacology

Avec: Megan Beetch , Sadaf Harandi-Zadeh , Kate Shen , Katarzyna Lubecka , David D Kitts , Heather M O'Hagan , Barbara Stefanska

Overexpression of Pdx1, reduction of p53, or deletion of CHOP attenuates pancreas hypoplasia in mice with pancreas-specific O-GlcNAc transferase deletion.

The Journal of biological chemistry

Avec: Alicia Wong , Samantha Pritchard , Mackenzie Moore , Brian Akhaphong , Nandini Avula , Megan Beetch , Yoshio Fujitani , Emilyn U Alejandro

Targeted and selective knockout of the TLQP-21 neuropeptide unmasks its unique role in energy homeostasis.

bioRxiv : the preprint server for biology

Epigenetic aberrations of gene expression in a rat model of hepatocellular carcinoma.

Epigenetics

Avec: Cayla Boycott , Megan Beetch , Tony Yang , Katarzyna Lubecka , Yuexi Ma , Jiaxi Zhang , Lucinda Kurzava Kendall , Melissa Ullmer , Benjamin S Ramsey , Sandra Torregrosa-Allen , Bennett D Elzey , Abigail Cox , Nadia Atallah Lanman , Alisa Hui , Nathaniel Villanueva , Aline de Conti , Tao Huan , Igor Pogribny , Barbara Stefanska

Placental mTOR complex 1 regulates fetal programming of obesity and insulin resistance in mice.

JCI insight

Avec: Brian Akhaphong , Daniel C Baumann , Megan Beetch , Amber D Lockridge , Seokwon Jo , Alicia Wong , Tate Zemanovic , Ramkumar Mohan , Danica L Fondevilla , Michelle Sia , Maria Ruth B Pineda-Cortel , Emilyn U Alejandro

Disruption of O-Linked N-Acetylglucosamine Signaling in Placenta Induces Insulin Sensitivity in Female Offspring.

International journal of molecular sciences

Avec: Mackenzie Moore , Nandini Avula , Seokwon Jo , Megan Beetch , Emilyn U Alejandro

Impact of placental mTOR deficiency on peripheral insulin signaling in adult mice offspring.

Journal of molecular endocrinology

Avec: Megan Beetch , Brian Akhaphong , Alicia Wong , Briana Clifton , Seokwon Jo , Ramkumar Mohan , Juan E Abrahante Llorens , Emilyn U Alejandro

Sex Differences in Pancreatic β-Cell Physiology and Glucose Homeostasis in C57BL/6J Mice.

Journal of the Endocrine Society

Avec: Seokwon Jo , Megan Beetch , Eric Gustafson , Alicia Wong , Eunice Oribamise , Grace Chung , Suryakiran Vadrevu , Leslie S Satin , Ernesto Bernal-Mizrachi , Emilyn U Alejandro

Réseau de co-auteurs

Barbara Stefanska 8 collaborations

Emilyn U Alejandro 8 collaborations

Seokwon Jo 7 collaborations

Sadaf Harandi-Zadeh 6 collaborations

Cayla Boycott 6 collaborations

Tony Yang 6 collaborations

Katarzyna Lubecka 5 collaborations

Alicia Wong 5 collaborations

Mackenzie Moore 3 collaborations

Nandini Avula 3 collaborations

Ramkumar Mohan 3 collaborations

Brian Akhaphong 3 collaborations

Benjamin J E Martin 2 collaborations

Kevin Ren 2 collaborations

John H Dupuis 2 collaborations

Rickey Y Yada 2 collaborations

LeAnn J Howe 2 collaborations

Bhavani S Sahu 2 collaborations

Maria Razzoli 2 collaborations

Seth McGonigle 2 collaborations

Jean Pierre Pallais 2 collaborations

Megin E Nguyen 2 collaborations

Masato Sadahiro 2 collaborations

Cheng Jiang 2 collaborations

Wei-Jye Lin 2 collaborations

Kevin A Kelley 2 collaborations

Pedro Rodriguez 2 collaborations

Rachel Mansk 2 collaborations

Cheryl Cero 2 collaborations

Giada Caviola 2 collaborations

Paola Palanza 2 collaborations

Loredana Rao 2 collaborations

Emilyn Alejandro 2 collaborations

Yuk Y Sham 2 collaborations

Andrea Frontini 2 collaborations

Stephen R Salton 2 collaborations

Alessandro Bartolomucci 2 collaborations

Kate Shen 2 collaborations

Yihang Chen 2 collaborations

Sulma I Mohammed 2 collaborations

Melissa Ullmer 2 collaborations

Yuexi Ma 2 collaborations

Eric Gustafson 2 collaborations

Grace Chung 2 collaborations

Anna Kwasniak 1 collaboration

Kirsty Flower 1 collaboration

Matthew Suderman 1 collaboration

James M Flanagan 1 collaboration

Thomas Dixon-McDougall 1 collaboration

Allison Gacad 1 collaboration

Carolyn J Brown 1 collaboration

Kamil Ziarniak 1 collaboration

Maciej Sassek 1 collaboration

Emilia Grzeda 1 collaboration

Joanna H Sliwowska 1 collaboration

Ahmad Essawy 1 collaboration

Amber Lockridge 1 collaboration

Emilyn Uy Alejandro 1 collaboration

David D Kitts 1 collaboration

Heather M O'Hagan 1 collaboration

Samantha Pritchard 1 collaboration

Yoshio Fujitani 1 collaboration

Jiaxi Zhang 1 collaboration

Lucinda Kurzava Kendall 1 collaboration

Benjamin S Ramsey 1 collaboration

Sandra Torregrosa-Allen 1 collaboration

Bennett D Elzey 1 collaboration

Abigail Cox 1 collaboration

Nadia Atallah Lanman 1 collaboration

Alisa Hui 1 collaboration

Nathaniel Villanueva 1 collaboration

Aline de Conti 1 collaboration

Tao Huan 1 collaboration

Igor Pogribny 1 collaboration

Daniel C Baumann 1 collaboration

Amber D Lockridge 1 collaboration

Tate Zemanovic 1 collaboration

Danica L Fondevilla 1 collaboration

Michelle Sia 1 collaboration

Maria Ruth B Pineda-Cortel 1 collaboration

Briana Clifton 1 collaboration

Juan E Abrahante Llorens 1 collaboration

Eunice Oribamise 1 collaboration

Suryakiran Vadrevu 1 collaboration

Leslie S Satin 1 collaboration

Ernesto Bernal-Mizrachi 1 collaboration