Muhammad Tehseen

Affiliations

Bioscience Program, Division of Biological and Environmental Sciences and Engineering, King Abdullah University of Science and Technology, Thuwal 23955, Saudi Arabia.

Publications (30)

Elevated Soluble Galectin-3 as a Marker of Chemotherapy Efficacy in Breast Cancer Patients: A Prospective Study.

International journal of breast cancer

Avec: Arooj Shafiq , January Moore , Aliya Suleman , Sabeen Faiz , Omar Farooq , Adnan Arshad , Mohammad Tehseen , Ammarah Zafar , Syed Haider Ali , Nasir Ud Din , Asif Loya , Neelam Siddiqui , Fatima K Rehman

Single-molecule characterization of SV40 replisome and novel factors: human FPC and Mcm10.

Nucleic acids research

Avec: Yujing Ouyang , Amani Al-Amodi , Muhammad Tehseen , Lubna Alhudhali , Afnan Shirbini , Masateru Takahashi , Vlad-Stefan Raducanu , Gang Yi , Ammar Usman Danazumi , Alfredo De Biasio , Samir M Hamdan

Modulation of the microhomology-mediated end joining pathway suppresses large deletions and enhances homology-directed repair following CRISPR-Cas9-induced DNA breaks.

BMC biology

Avec: Baolei Yuan , Chongwei Bi , Yeteng Tian , Jincheng Wang , Yiqing Jin , Khaled Alsayegh , Muhammad Tehseen , Gang Yi , Xuan Zhou , Yanjiao Shao , Fernanda Vargas Romero , Wolfgang Fischle , Juan Carlos Izpisua Belmonte , Samir Hamdan , Yanyi Huang , Mo Li

Development of Multiplex Real-Time RT-qPCR Assays for the Detection of SARS-CoV-2, Influenza A/B, and MERS-CoV.

Journal of visualized experiments : JoVE

Avec: Atheer Althobaiti , Kareem Hamdan , Mohamed A Sobhy , Renad Rawas , Masateru Takahashi , Olga Artyukh , Muhammad Tehseen

Functional binding of E-selectin to its ligands is enhanced by structural features beyond its lectin domain.

The Journal of biological chemistry

Avec: Fajr A Aleisa , Kosuke Sakashita , Jae Man Lee , Dina B AbuSamra , Bader Al Alwan , Shuho Nozue , Muhammad Tehseen , Samir M Hamdan , Satoshi Habuchi , Takahiro Kusakabe , Jasmeen S Merzaban

Fusion of the Cas9 endonuclease and the VirD2 relaxase facilitates homology-directed repair for precise genome engineering in rice.

Communications biology

Avec: Zahir Ali , Ashwag Shami , Khalid Sedeek , Radwa Kamel , Abdulrahman Alhabsi , Muhammad Tehseen , Norhan Hassan , Haroon Butt , Ahad Kababji , Samir M Hamdan , Magdy M Mahfouz

Initial state of DNA-Dye complex sets the stage for protein induced fluorescence modulation.

Nature communications

Avec: Fahad Rashid , Vlad-Stefan Raducanu , Manal S Zaher , Muhammad Tehseen , Satoshi Habuchi , Samir M Hamdan

Single-Molecule Förster Resonance Energy Transfer Methods for Real-Time Investigation of the Holliday Junction Resolution by GEN1.

Journal of visualized experiments : JoVE

Avec: Mohamed A Sobhy , Amer Bralić , Vlad-Stefan Raducanu , Muhammad Tehseen , Yujing Ouyang , Masateru Takahashi , Fahad Rashid , Manal S Zaher , Samir M Hamdan

Bio-SCAN: A CRISPR/dCas9-Based Lateral Flow Assay for Rapid, Specific, and Sensitive Detection of SARS-CoV-2.

ACS synthetic biology

Avec: Zahir Ali , Edith Sánchez , Muhammad Tehseen , Ahmed Mahas , Tin Marsic , Rashid Aman , Gundra Sivakrishna Rao , Fatimah Saeed Alhamlan , Madain S Alsanea , Ahmed A Al-Qahtani , Samir Hamdan , Magdy Mahfouz

Resolution of the Holliday junction recombination intermediate by human GEN1 at the single-molecule level.

Nucleic acids research

Avec: Mohamed A Sobhy , Amer Bralić , Vlad-Stefan Raducanu , Masateru Takahashi , Muhammad Tehseen , Fahad Rashid , Manal S Zaher , Samir M Hamdan

Two chromatographic schemes for protein purification involving the biotin/avidin interaction under native conditions.

Journal of chromatography. A

Avec: Vlad-Stefan Raducanu , Muhammad Tehseen , Afnan Shirbini , Daniela-Violeta Raducanu , Samir M Hamdan

Implementing fluorescence enhancement, quenching, and FRET for investigating flap endonuclease 1 enzymatic reaction at the single-molecule level.

Computational and structural biotechnology journal

Avec: Mohamed A Sobhy , Muhammad Tehseen , Masateru Takahashi , Amer Bralić , Alfredo De Biasio , Samir M Hamdan

Wiskott-Aldrich syndrome protein forms nuclear condensates and regulates alternative splicing.

Nature communications

Avec: Baolei Yuan , Xuan Zhou , Keiichiro Suzuki , Gerardo Ramos-Mandujano , Mengge Wang , Muhammad Tehseen , Lorena V Cortés-Medina , James J Moresco , Sarah Dunn , Reyna Hernandez-Benitez , Tomoaki Hishida , Na Young Kim , Manal M Andijani , Chongwei Bi , Manching Ku , Yuta Takahashi , Jinna Xu , Jinsong Qiu , Ling Huang , Christopher Benner , Emi Aizawa , Jing Qu , Guang-Hui Liu , Zhongwei Li , Fei Yi , Yanal Ghosheh , Changwei Shao , Maxim Shokhirev , Patrizia Comoli , Francesco Frassoni , John R Yates , Xiang-Dong Fu , Concepcion Rodriguez Esteban , Samir Hamdan , Juan Carlos Izpisua Belmonte , Mo Li

Efficient in planta production of amidated antimicrobial peptides that are active against drug-resistant ESKAPE pathogens.

Nature communications

Avec: Shahid Chaudhary , Zahir Ali , Muhammad Tehseen , Evan F Haney , Aarón Pantoja-Angles , Salwa Alshehri , Tiannyu Wang , Gerard J Clancy , Maya Ayach , Charlotte Hauser , Pei-Ying Hong , Samir M Hamdan , Robert E W Hancock , Magdy Mahfouz

Quick and Easy Assembly of a One-Step qRT-PCR Kit for COVID-19 Diagnostics Using In-House Enzymes.

ACS omega

Avec: Masateru Takahashi , Muhammad Tehseen , Rahul Salunke , Etsuko Takahashi , Sara Mfarrej , Mohamed A Sobhy , Fatimah S Alhamlan , Sharif Hala , Gerardo Ramos-Mandujano , Ahmed A Al-Qahtani , Fadwa S Alofi , Afrah Alsomali , Anwar M Hashem , Asim Khogeer , Naif A M Almontashiri , Jae Man Lee , Hiroaki Mon , Kosuke Sakashita , Mo Li , Takahiro Kusakabe , Arnab Pain , Samir M Hamdan

TSGIT: An N- and C-terminal tandem tag system for purification of native and intein-mediated ligation-ready proteins.

Protein science : a publication of the Protein Society

Avec: Vlad-Stefan Raducanu , Daniela-Violeta Raducanu , Yujing Ouyang , Muhammad Tehseen , Masateru Takahashi , Samir M Hamdan

Using Eukaryotic Expression Systems to Generate Human α1,3-Fucosyltransferases That Effectively Create Selectin-Binding Glycans on Stem Cells.

Biochemistry

Avec: Asma S Al-Amoodi , Kosuke Sakashita , Amal J Ali , Ruoyu Zhou , Jae Man Lee , Muhammad Tehseen , Mo Li , Juan Carlos I Belmonte , Takahiro Kusakabe , Jasmeen S Merzaban

Vigilant: An Engineered VirD2-Cas9 Complex for Lateral Flow Assay-Based Detection of SARS-CoV2.

Nano letters

Avec: Tin Marsic , Zahir Ali , Muhammad Tehseen , Ahmed Mahas , Samir Hamdan , Magdy Mahfouz

Cryo-EM structure of human Pol κ bound to DNA and mono-ubiquitylated PCNA.

Nature communications

Avec: Claudia Lancey , Muhammad Tehseen , Souvika Bakshi , Matthew Percival , Masateru Takahashi , Mohamed A Sobhy , Vlad S Raducanu , Kerry Blair , Frederick W Muskett , Timothy J Ragan , Ramon Crehuet , Samir M Hamdan , Alfredo De Biasio

Mechanistic investigation of human maturation of Okazaki fragments reveals slow kinetics.

Nature communications

Avec: Vlad-Stefan Raducanu , Muhammad Tehseen , Amani Al-Amodi , Luay I Joudeh , Alfredo De Biasio , Samir M Hamdan

A scanning-to-incision switch in TFIIH-XPG induced by DNA damage licenses nucleotide excision repair.

Nucleic acids research

Avec: Amer Bralić , Muhammad Tehseen , Mohamed A Sobhy , Chi-Lin Tsai , Lubna Alhudhali , Gang Yi , Jina Yu , Chunli Yan , Ivaylo Ivanov , Susan E Tsutakawa , John A Tainer , Samir M Hamdan

Mechanism of human Lig1 regulation by PCNA in Okazaki fragment sealing.

Nature communications

Avec: Kerry Blair , Muhammad Tehseen , Vlad-Stefan Raducanu , Taha Shahid , Claudia Lancey , Fahad Rashid , Ramon Crehuet , Samir M Hamdan , Alfredo De Biasio

Structure of the processive human Pol δ holoenzyme.

Nature communications

Avec: Claudia Lancey , Muhammad Tehseen , Vlad-Stefan Raducanu , Fahad Rashid , Nekane Merino , Timothy J Ragan , Christos G Savva , Manal S Zaher , Afnan Shirbini , Francisco J Blanco , Samir M Hamdan , Alfredo De Biasio

iSCAN: An RT-LAMP-coupled CRISPR-Cas12 module for rapid, sensitive detection of SARS-CoV-2.

Virus research

Avec: Zahir Ali , Rashid Aman , Ahmed Mahas , Gundra Sivakrishna Rao , Muhammad Tehseen , Tin Marsic , Rahul Salunke , Amit K Subudhi , Sharif M Hala , Samir M Hamdan , Arnab Pain , Fadwa S Alofi , Afrah Alsomali , Anwar M Hashem , Asim Khogeer , Naif A M Almontashiri , Malak Abedalthagafi , Norhan Hassan , Magdy M Mahfouz

Proliferating cell nuclear antigen-agarose column: A tag-free and tag-dependent tool for protein purification affinity chromatography.

Journal of chromatography. A

Avec: Muhammad Tehseen , Vlad-Stefan Raducanu , Fahad Rashid , Afnan Shirbini , Masateru Takahashi , Samir M Hamdan

An open-source, automated, and cost-effective platform for COVID-19 diagnosis and rapid portable genomic surveillance using nanopore sequencing.

Scientific reports

Avec: Gerardo Ramos-Mandujano , Raik Grünberg , Yingzi Zhang , Chongwei Bi , Francisco J Guzmán-Vega , Muhammad Shuaib , Rodion V Gorchakov , Jinna Xu , Muhammad Tehseen , Masateru Takahashi , Etsuko Takahashi , Ashraf Dada , Adeel Nazir Ahmad , Samir M Hamdan , Arnab Pain , Stefan T Arold , Mo Li

Cryo-electron structures of the extreme thermostable enzymes Sulfur Oxygenase Reductase and Lumazine Synthase.

PloS one

Avec: Mohamed A Sobhy , Lingyun Zhao , Dalaver Anjum , Ali Behzad , Masateru Takahashi , Muhammad Tehseen , Alfredo De Biasio , Rachid Sougrat , Samir Hamdan

Interaction of human HelQ with DNA polymerase delta halts DNA synthesis and stimulates DNA single-strand annealing.

Nucleic acids research

Avec: Liu He , Rebecca Lever , Andrew Cubbon , Muhammad Tehseen , Tabitha Jenkins , Alice O Nottingham , Anya Horton , Hannah Betts , Martin Fisher , Samir M Hamdan , Panos Soultanas , Edward L Bolt

Severe Combined Immunodeficiency from a Homozygous DNA Ligase 1 Mutant with Reduced Catalytic Activity but Increased Ligation Fidelity.

Journal of clinical immunology

Avec: Huda Alajlan , Vlad-Stefan Raducanu , Yossef Lopez de Los Santos , Muhammad Tehseen , Hibah Alruwaili , Amer Al-Mazrou , Reem Mohammad , Monther Al-Alwan , Alfredo De Biasio , Jasmeen S Merzaban , Hamoud Al-Mousa , Samir M Hamdan , Anas M Alazami

Revised mechanism of hydroxyurea-induced cell cycle arrest and an improved alternative.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Alisa E Shaw , Mattias N Mihelich , Jackson E Whitted , Hannah J Reitman , Adam J Timmerman , Muhammad Tehseen , Samir M Hamdan , Grant D Schauer

Réseau de co-auteurs

Samir M Hamdan 22 collaborations

Masateru Takahashi 11 collaborations

Vlad-Stefan Raducanu 11 collaborations

Alfredo De Biasio 8 collaborations

Mohamed A Sobhy 8 collaborations

Fahad Rashid 6 collaborations

Samir Hamdan 5 collaborations

Mo Li 5 collaborations

Zahir Ali 5 collaborations

Afnan Shirbini 4 collaborations

Manal S Zaher 4 collaborations

Amer Bralić 4 collaborations

Yujing Ouyang 3 collaborations

Gang Yi 3 collaborations

Chongwei Bi 3 collaborations

Kosuke Sakashita 3 collaborations

Jae Man Lee 3 collaborations

Takahiro Kusakabe 3 collaborations

Jasmeen S Merzaban 3 collaborations

Ahmed Mahas 3 collaborations

Tin Marsic 3 collaborations

Magdy Mahfouz 3 collaborations

Gerardo Ramos-Mandujano 3 collaborations

Arnab Pain 3 collaborations

Claudia Lancey 3 collaborations

Amani Al-Amodi 2 collaborations

Lubna Alhudhali 2 collaborations

Baolei Yuan 2 collaborations

Xuan Zhou 2 collaborations

Juan Carlos Izpisua Belmonte 2 collaborations

Satoshi Habuchi 2 collaborations

Norhan Hassan 2 collaborations

Magdy M Mahfouz 2 collaborations

Rashid Aman 2 collaborations

Gundra Sivakrishna Rao 2 collaborations

Ahmed A Al-Qahtani 2 collaborations

Daniela-Violeta Raducanu 2 collaborations

Jinna Xu 2 collaborations

Rahul Salunke 2 collaborations

Etsuko Takahashi 2 collaborations

Fadwa S Alofi 2 collaborations

Afrah Alsomali 2 collaborations

Anwar M Hashem 2 collaborations

Asim Khogeer 2 collaborations

Naif A M Almontashiri 2 collaborations

Kerry Blair 2 collaborations

Timothy J Ragan 2 collaborations

Ramon Crehuet 2 collaborations

Arooj Shafiq 1 collaboration

January Moore 1 collaboration

Aliya Suleman 1 collaboration

Sabeen Faiz 1 collaboration

Omar Farooq 1 collaboration

Adnan Arshad 1 collaboration

Mohammad Tehseen 1 collaboration

Ammarah Zafar 1 collaboration

Syed Haider Ali 1 collaboration

Nasir Ud Din 1 collaboration

Asif Loya 1 collaboration

Neelam Siddiqui 1 collaboration

Fatima K Rehman 1 collaboration

Ammar Usman Danazumi 1 collaboration

Yeteng Tian 1 collaboration

Jincheng Wang 1 collaboration

Yiqing Jin 1 collaboration

Khaled Alsayegh 1 collaboration

Yanjiao Shao 1 collaboration

Fernanda Vargas Romero 1 collaboration

Wolfgang Fischle 1 collaboration

Yanyi Huang 1 collaboration

Atheer Althobaiti 1 collaboration

Kareem Hamdan 1 collaboration

Renad Rawas 1 collaboration

Olga Artyukh 1 collaboration

Fajr A Aleisa 1 collaboration

Dina B AbuSamra 1 collaboration

Bader Al Alwan 1 collaboration

Shuho Nozue 1 collaboration

Ashwag Shami 1 collaboration

Khalid Sedeek 1 collaboration

Radwa Kamel 1 collaboration

Abdulrahman Alhabsi 1 collaboration

Haroon Butt 1 collaboration

Ahad Kababji 1 collaboration

Edith Sánchez 1 collaboration

Fatimah Saeed Alhamlan 1 collaboration

Madain S Alsanea 1 collaboration

Keiichiro Suzuki 1 collaboration

Mengge Wang 1 collaboration

Lorena V Cortés-Medina 1 collaboration

James J Moresco 1 collaboration

Sarah Dunn 1 collaboration

Reyna Hernandez-Benitez 1 collaboration

Tomoaki Hishida 1 collaboration

Na Young Kim 1 collaboration

Manal M Andijani 1 collaboration

Manching Ku 1 collaboration

Yuta Takahashi 1 collaboration

Jinsong Qiu 1 collaboration

Ling Huang 1 collaboration

Christopher Benner 1 collaboration

Emi Aizawa 1 collaboration

Jing Qu 1 collaboration

Guang-Hui Liu 1 collaboration

Zhongwei Li 1 collaboration

Fei Yi 1 collaboration

Yanal Ghosheh 1 collaboration

Changwei Shao 1 collaboration

Maxim Shokhirev 1 collaboration

Patrizia Comoli 1 collaboration

Francesco Frassoni 1 collaboration

John R Yates 1 collaboration

Xiang-Dong Fu 1 collaboration

Concepcion Rodriguez Esteban 1 collaboration

Shahid Chaudhary 1 collaboration

Evan F Haney 1 collaboration

Aarón Pantoja-Angles 1 collaboration

Salwa Alshehri 1 collaboration

Tiannyu Wang 1 collaboration

Gerard J Clancy 1 collaboration

Maya Ayach 1 collaboration

Charlotte Hauser 1 collaboration

Pei-Ying Hong 1 collaboration

Robert E W Hancock 1 collaboration

Sara Mfarrej 1 collaboration

Fatimah S Alhamlan 1 collaboration

Sharif Hala 1 collaboration

Hiroaki Mon 1 collaboration

Asma S Al-Amoodi 1 collaboration

Amal J Ali 1 collaboration

Ruoyu Zhou 1 collaboration

Juan Carlos I Belmonte 1 collaboration

Souvika Bakshi 1 collaboration

Matthew Percival 1 collaboration

Vlad S Raducanu 1 collaboration

Frederick W Muskett 1 collaboration

Luay I Joudeh 1 collaboration

Chi-Lin Tsai 1 collaboration

Jina Yu 1 collaboration

Chunli Yan 1 collaboration

Ivaylo Ivanov 1 collaboration

Susan E Tsutakawa 1 collaboration

John A Tainer 1 collaboration

Taha Shahid 1 collaboration

Nekane Merino 1 collaboration

Christos G Savva 1 collaboration

Francisco J Blanco 1 collaboration

Amit K Subudhi 1 collaboration

Sharif M Hala 1 collaboration

Malak Abedalthagafi 1 collaboration

Raik Grünberg 1 collaboration

Yingzi Zhang 1 collaboration

Francisco J Guzmán-Vega 1 collaboration

Muhammad Shuaib 1 collaboration

Rodion V Gorchakov 1 collaboration

Ashraf Dada 1 collaboration

Adeel Nazir Ahmad 1 collaboration

Stefan T Arold 1 collaboration

Lingyun Zhao 1 collaboration

Dalaver Anjum 1 collaboration

Ali Behzad 1 collaboration

Rachid Sougrat 1 collaboration

Liu He 1 collaboration

Rebecca Lever 1 collaboration

Andrew Cubbon 1 collaboration

Tabitha Jenkins 1 collaboration

Alice O Nottingham 1 collaboration

Anya Horton 1 collaboration

Hannah Betts 1 collaboration

Martin Fisher 1 collaboration

Panos Soultanas 1 collaboration

Edward L Bolt 1 collaboration

Huda Alajlan 1 collaboration

Yossef Lopez de Los Santos 1 collaboration

Hibah Alruwaili 1 collaboration

Amer Al-Mazrou 1 collaboration

Reem Mohammad 1 collaboration

Monther Al-Alwan 1 collaboration

Hamoud Al-Mousa 1 collaboration

Anas M Alazami 1 collaboration

Alisa E Shaw 1 collaboration

Mattias N Mihelich 1 collaboration

Jackson E Whitted 1 collaboration

Hannah J Reitman 1 collaboration

Adam J Timmerman 1 collaboration

Grant D Schauer 1 collaboration