Ray Truant

Affiliations

Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8N3Z5, Canada. Electronic address: truantr@mcmaster.ca.

Publications (16)

Single Cell Technologies Define New Therapeutic Avenues for Huntington's Disease.

Neuron

Avec: Tamara Maiuri , Ray Truant

High-mobility group box 1 links sensing of reactive oxygen species by huntingtin to its nuclear entry.

The Journal of biological chemistry

Avec: Susie Son , Laura E Bowie , Tamara Maiuri , Claudia L K Hung , Carly R Desmond , Jianrun Xia , Ray Truant

Spinocerebellar Ataxia Type 1 protein Ataxin-1 is signaled to DNA damage by ataxia-telangiectasia mutated kinase.

Human molecular genetics

Avec: Celeste E Suart , Alma M Perez , Ismael Al-Ramahi , Tamara Maiuri , Juan Botas , Ray Truant

PAM-Flexible Genome Editing with an Engineered Chimeric Cas9.

Research square

Avec: Sabrina Koseki , Lauren Hong , Vivian Yudistyra , Teodora Stan , Emma Tysinger , Rachel Silverstein , Christian Kramme , Nadia Amrani , Natasha Savic , Martin Pacesa , Tomás Rodriguez , Manvitha Ponnapati , Joseph Jacobson , George Church , Ray Truant , Martin Jinek , Benjamin Kleinstiver , Erik Sontheimer , Pranam Chatterjee

DNA Repair Signaling of Huntingtin: The Next Link Between Late-Onset Neurodegenerative Disease and Oxidative DNA Damage.

DNA and cell biology

Avec: Tamara Maiuri , Laura E Bowie , Ray Truant

Huntingtin structure is orchestrated by HAP40 and shows a polyglutamine expansion-specific interaction with exon 1.

Communications biology

Avec: Rachel J Harding , Justin C Deme , Johannes F Hevler , Sem Tamara , Alexander Lemak , Jeffrey P Cantle , Magdalena M Szewczyk , Nola Begeja , Siobhan Goss , Xiaobing Zuo , Peter Loppnau , Alma Seitova , Ashley Hutchinson , Lixin Fan , Ray Truant , Matthieu Schapira , Jeffrey B Carroll , Albert J R Heck , Susan M Lea , Cheryl H Arrowsmith

Mod3D: A low-cost, flexible modular system of live-cell microscopy chambers and holders.

PloS one

Avec: Siobhan Goss , Carlos Barba Bazan , Kaitlyn Neuman , Christina Peng , Nola Begeja , Celeste Elisabeth Suart , Ray Truant

Recent Microscopy Advances and the Applications to Huntington's Disease Research.

Journal of Huntington's disease

Avec: Mouhanad Babi , Kaitlyn Neuman , Christina Y Peng , Tamara Maiuri , Celeste E Suart , Ray Truant

Functional characterization of variants of unknown significance in a spinocerebellar ataxia patient using an unsupervised machine learning pipeline.

Human genome variation

Avec: Siddharth Nath , Nicholas S Caron , Linda May , Oxana B Gluscencova , Jill Kolesar , Lauren Brady , Brett A Kaufman , Gabrielle L Boulianne , Amadeo R Rodriguez , Mark A Tarnopolsky , Ray Truant

Shedding a new light on Huntington's disease: how blood can both propagate and ameliorate disease pathology.

Molecular psychiatry

Avec: Marie Rieux , Melanie Alpaugh , Giacomo Sciacca , Martine Saint-Pierre , Maria Masnata , Hélèna L Denis , Sébastien A Lévesque , Frank Herrmann , Chantal Bazenet , Alexandre P Garneau , Paul Isenring , Ray Truant , Abid Oueslati , Peter V Gould , Anne Ast , Erich E Wanker , Steve Lacroix , Francesca Cicchetti

DNA Repair in Huntington's Disease and Spinocerebellar Ataxias: Somatic Instability and Alternative Hypotheses.

Journal of Huntington's disease

Avec: Tamara Maiuri , Claudia L K Hung , Celeste Suart , Nola Begeja , Carlos Barba-Bazan , Yi Peng , Natasha Savic , Timothy Wong , Ray Truant

The impact of the COVID-19 pandemic on perceived publication pressure among academic researchers in Canada.

PloS one

Avec: Celeste Suart , Kaitlyn Neuman , Ray Truant

PAM-flexible genome editing with an engineered chimeric Cas9.

Nature communications

Avec: Lin Zhao , Sabrina R T Koseki , Rachel A Silverstein , Nadia Amrani , Christina Peng , Christian Kramme , Natasha Savic , Martin Pacesa , Tomás C Rodríguez , Teodora Stan , Emma Tysinger , Lauren Hong , Vivian Yudistyra , Manvitha R Ponnapati , Joseph M Jacobson , George M Church , Noah Jakimo , Ray Truant , Martin Jinek , Benjamin P Kleinstiver , Erik J Sontheimer , Pranam Chatterjee

Poly ADP-ribose signaling is dysregulated in Huntington disease.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Tamara Maiuri , Carlos Barba Bazan , Rachel J Harding , Nola Begeja , Tae-In Kam , Lauren M Byrne , Filipe B Rodrigues , Monica M Warner , Kaitlyn Neuman , Muqtasid Mansoor , Mohsen Badiee , Morgan Dasovich , Keona Wang , Leslie M Thompson , Anthony K L Leung , Sara N Andres , Edward J Wild , Ted M Dawson , Valina L Dawson , Cheryl H Arrowsmith , Ray Truant

Development of a knowledge translation platform for ataxia: Impact on readers and volunteer contributors.

PloS one

Avec: Celeste Elisabeth Suart , Katherine Jean Graham , Theresa Nowlan Suart , Ray Truant

DNA Damage Repair in Huntington's Disease and Other Neurodegenerative Diseases.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

Avec: T Maiuri , C E Suart , C L K Hung , K J Graham , C A Barba Bazan , R Truant

Réseau de co-auteurs

Tamara Maiuri 7 collaborations

Nola Begeja 4 collaborations

Kaitlyn Neuman 4 collaborations

Natasha Savic 3 collaborations

Laura E Bowie 2 collaborations

Claudia L K Hung 2 collaborations

Celeste E Suart 2 collaborations

Lauren Hong 2 collaborations

Vivian Yudistyra 2 collaborations

Teodora Stan 2 collaborations

Emma Tysinger 2 collaborations

Christian Kramme 2 collaborations

Nadia Amrani 2 collaborations

Martin Pacesa 2 collaborations

Martin Jinek 2 collaborations

Pranam Chatterjee 2 collaborations

Rachel J Harding 2 collaborations

Siobhan Goss 2 collaborations

Cheryl H Arrowsmith 2 collaborations

Carlos Barba Bazan 2 collaborations

Christina Peng 2 collaborations

Celeste Elisabeth Suart 2 collaborations

Celeste Suart 2 collaborations

Susie Son 1 collaboration

Carly R Desmond 1 collaboration

Jianrun Xia 1 collaboration

Alma M Perez 1 collaboration

Ismael Al-Ramahi 1 collaboration

Juan Botas 1 collaboration

Sabrina Koseki 1 collaboration

Rachel Silverstein 1 collaboration

Tomás Rodriguez 1 collaboration

Manvitha Ponnapati 1 collaboration

Joseph Jacobson 1 collaboration

George Church 1 collaboration

Benjamin Kleinstiver 1 collaboration

Erik Sontheimer 1 collaboration

Justin C Deme 1 collaboration

Johannes F Hevler 1 collaboration

Sem Tamara 1 collaboration

Alexander Lemak 1 collaboration

Jeffrey P Cantle 1 collaboration

Magdalena M Szewczyk 1 collaboration

Xiaobing Zuo 1 collaboration

Peter Loppnau 1 collaboration

Alma Seitova 1 collaboration

Ashley Hutchinson 1 collaboration

Lixin Fan 1 collaboration

Matthieu Schapira 1 collaboration

Jeffrey B Carroll 1 collaboration

Albert J R Heck 1 collaboration

Susan M Lea 1 collaboration

Mouhanad Babi 1 collaboration

Christina Y Peng 1 collaboration

Siddharth Nath 1 collaboration

Nicholas S Caron 1 collaboration

Linda May 1 collaboration

Oxana B Gluscencova 1 collaboration

Jill Kolesar 1 collaboration

Lauren Brady 1 collaboration

Brett A Kaufman 1 collaboration

Gabrielle L Boulianne 1 collaboration

Amadeo R Rodriguez 1 collaboration

Mark A Tarnopolsky 1 collaboration

Marie Rieux 1 collaboration

Melanie Alpaugh 1 collaboration

Giacomo Sciacca 1 collaboration

Martine Saint-Pierre 1 collaboration

Maria Masnata 1 collaboration

Hélèna L Denis 1 collaboration

Sébastien A Lévesque 1 collaboration

Frank Herrmann 1 collaboration

Chantal Bazenet 1 collaboration

Alexandre P Garneau 1 collaboration

Paul Isenring 1 collaboration

Abid Oueslati 1 collaboration

Peter V Gould 1 collaboration

Anne Ast 1 collaboration

Erich E Wanker 1 collaboration

Steve Lacroix 1 collaboration

Francesca Cicchetti 1 collaboration

Carlos Barba-Bazan 1 collaboration

Yi Peng 1 collaboration

Timothy Wong 1 collaboration

Lin Zhao 1 collaboration

Sabrina R T Koseki 1 collaboration

Rachel A Silverstein 1 collaboration

Tomás C Rodríguez 1 collaboration

Manvitha R Ponnapati 1 collaboration

Joseph M Jacobson 1 collaboration

George M Church 1 collaboration

Noah Jakimo 1 collaboration

Benjamin P Kleinstiver 1 collaboration

Erik J Sontheimer 1 collaboration

Tae-In Kam 1 collaboration

Lauren M Byrne 1 collaboration

Filipe B Rodrigues 1 collaboration

Monica M Warner 1 collaboration

Muqtasid Mansoor 1 collaboration

Mohsen Badiee 1 collaboration

Morgan Dasovich 1 collaboration

Keona Wang 1 collaboration

Leslie M Thompson 1 collaboration

Anthony K L Leung 1 collaboration

Sara N Andres 1 collaboration

Edward J Wild 1 collaboration

Ted M Dawson 1 collaboration

Valina L Dawson 1 collaboration

Katherine Jean Graham 1 collaboration

Theresa Nowlan Suart 1 collaboration

T Maiuri 1 collaboration

C E Suart 1 collaboration

C L K Hung 1 collaboration

K J Graham 1 collaboration

C A Barba Bazan 1 collaboration

R Truant 1 collaboration