Saiful E Syafruddin

Affiliations

UKM Medical Molecular Biology Institute (UMBI), Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur 56000, Malaysia.

Publications (28)

Epigenome-Wide DNA Methylation Profiling in Colorectal Cancer and Normal Adjacent Colon Using Infinium Human Methylation 450K.

Diagnostics (Basel, Switzerland)

Avec: Rashidah Baharudin , Muhiddin Ishak , Azliana Muhamad Yusof , Sazuita Saidin , Saiful Effendi Syafruddin , Wan Fahmi Wan Mohamad Nazarie , Learn-Han Lee , Nurul-Syakima Ab Mutalib

Recent progress in mass spectrometry-based strategies for elucidating protein-protein interactions.

Cellular and molecular life sciences : CMLS

Avec: Teck Yew Low , Saiful Effendi Syafruddin , M Aiman Mohtar , Adaikkalam Vellaichamy , Nisa Syakila A Rahman , Yuh-Fen Pung , Chris Soon Heng Tan

Potential Roles of microRNAs for Assessing Cardiovascular Risk in Pre-Eclampsia-Exposed Postpartum Women and Offspring.

International journal of molecular sciences

Avec: Nurul Iffah Mohd Isa , Saiful Effendi Syafruddin , Mohd Helmy Mokhtar , Shahidee Zainal Abidin , Farah Hanan Fathihah Jaffar , Azizah Ugusman , Adila A Hamid

Cancer Cell-Derived PDGFB Stimulates mTORC1 Activation in Renal Carcinoma.

International journal of molecular sciences

Avec: Asmaa Y Abuhamad , Nurul Nadia Mohamad Zamberi , Sakari Vanharanta , Siti Nur Hasanah Mohd Yusuf , M Aiman Mohtar , Saiful Effendi Syafruddin

dCas9 Tells Tales: Probing Gene Function and Transcription Regulation in Cancer.

The CRISPR journal

Avec: Nurul Nadia Mohamad Zamberi , Asmaa Y Abuhamad , Teck Yew Low , M Aiman Mohtar , Saiful Effendi Syafruddin

IL-8 and PI3K pathway influence the susceptibility of TRAIL-sensitive colorectal cancer cells to TRAIL-induced cell death.

Molecular biology reports

Avec: Kelly Xue Jing Jong , Elsa Haniffah Mejia Mohamed , Saiful Effendi Syafruddin , Farid Nazer Faruqu , Kumutha Malar Vellasamy , Kamariah Ibrahim , Zaridatul Aini Ibrahim

Two Sides of the Same Coin: The Roles of KLF6 in Physiology and Pathophysiology.

Biomolecules

Avec: Saiful E Syafruddin , M Aiman Mohtar , Wan Fahmi Wan Mohamad Nazarie , Teck Yew Low

CD44: A Multifunctional Mediator of Cancer Progression.

Biomolecules

Avec: Malak Hassn Mesrati , Saiful Effendi Syafruddin , M Aiman Mohtar , Amir Syahir

Functions and mechanisms of protein disulfide isomerase family in cancer emergence.

Cell & bioscience

Avec: Nisa Syakila A Rahman , Syazalina Zahari , Saiful Effendi Syafruddin , Mohd Firdaus-Raih , Teck Yew Low , M Aiman Mohtar

HOXA10 DNA Methylation Level in the Endometrium Women with Endometriosis: A Systematic Review.

Biology

Avec: Marjanu Hikmah Elias , Nurunnajah Lazim , Zulazmi Sutaji , Mohammad Azrai Abu , Abdul Kadir Abdul Karim , Azizah Ugusman , Saiful Effendi Syafruddin , Mohd Helmy Mokhtar , Mohd Faizal Ahmad

Impact of the Cancer Cell Secretome in Driving Breast Cancer Progression.

Cancers

Avec: Syazalina Zahari , Saiful Effendi Syafruddin , M Aiman Mohtar

Revisiting the Roles of Pro-Metastatic EpCAM in Cancer.

Biomolecules

Avec: M Aiman Mohtar , Saiful Effendi Syafruddin , Siti Nurmi Nasir , Teck Yew Low

Integration of RNA-Seq and proteomics data identifies glioblastoma multiforme surfaceome signature.

BMC cancer

Avec: Saiful Effendi Syafruddin , Wan Fahmi Wan Mohamad Nazarie , Nurshahirah Ashikin Moidu , Bee Hong Soon , M Aiman Mohtar

Interleukin-1 alpha and high mobility group box-1 secretion in polyinosinic:polycytidylic-induced colorectal cancer cells occur via RIPK1-dependent mechanism and participate in tumourigenesis.

Journal of cell communication and signaling

Avec: Kim Jun Cheng , Elsa Haniffah Mejia Mohamed , Saiful Effendi Syafruddin , Zaridatul Aini Ibrahim

Whole genome sequencing of Malaysian colorectal cancer patients reveals specific druggable somatic mutations.

Frontiers in molecular biosciences

Avec: Ryia Illani Mohd Yunos , Nurul-Syakima Ab Mutalib , Jia-Shiun Khoo , Sazuita Saidin , Muhiddin Ishak , Saiful Effendi Syafruddin , Francis Yew Fu Tieng , Najwa Farhah Md Yusof , Mohd Ridhwan Abd Razak , Norshahidah Mahamad Nadzir , Nadiah Abu , Isa Md Rose , Ismail Sagap , Luqman Mazlan , Rahman Jamal

Profiling of Differentially Expressed MicroRNAs in Human Umbilical Vein Endothelial Cells Exposed to Hyperglycemia via RNA Sequencing.

Life (Basel, Switzerland)

Avec: Nur Syakirah Othman , Amilia Aminuddin , Shahidee Zainal Abidin , Saiful Effendi Syafruddin , Mohd Faizal Ahmad , Norfilza Mohd Mokhtar , Jaya Kumar , Adila A Hamid , Azizah Ugusman

The Promises and Pitfalls of CRISPR-Mediated Base Editing in Stem Cells.

The CRISPR journal

Avec: Poh Kuan Wong , Nurul Nadia Mohamad Zamberi , Saiful Effendi Syafruddin , Fook Choe Cheah , Norazrina Azmi , Jia Xian Law , Eng Wee Chua

A KLF6-driven transcriptional network links lipid homeostasis and tumour growth in renal carcinoma.

Nature communications

Avec: Saiful E Syafruddin , Paulo Rodrigues , Erika Vojtasova , Saroor A Patel , M Nazhif Zaini , Johanna Burge , Anne Y Warren , Grant D Stewart , Tim Eisen , Dóra Bihary , Shamith A Samarajiwa , Sakari Vanharanta

More Than Meets the Eye: Revisiting the Roles of Heat Shock Factor 4 in Health and Diseases.

Biomolecules

Avec: Saiful Effendi Syafruddin , Sheen Ling , Teck Yew Low , M Aiman Mohtar

CRISPR Gene-Editing Models Geared Toward Therapy for Hereditary and Developmental Neurological Disorders.

Frontiers in pediatrics

Avec: Poh Kuan Wong , Fook Choe Cheah , Saiful Effendi Syafruddin , M Aiman Mohtar , Norazrina Azmi , Pei Yuen Ng , Eng Wee Chua

Expression of

International journal of molecular sciences

Avec: Nurunnajah Lazim , Marjanu Hikmah Elias , Zulazmi Sutaji , Abdul Kadir Abdul Karim , Mohammad Azrai Abu , Azizah Ugusman , Saiful Effendi Syafruddin , Mohd Helmy Mokhtar , Mohd Faizal Ahmad

Unravelling the role of HAS2, GREM1, and PTGS2 gene expression in cumulus cells: implications for human oocyte development competency - a systematic review and integrated bioinformatic analysis.

Frontiers in endocrinology

Avec: Ahmad Mohd Faizal , Marjanu Hikmah Elias , Norazilah Mat Jin , Muhammad Azrai Abu , Saiful Effendi Syafruddin , Ani Amelia Zainuddin , Nao Suzuki , Abdul Kadir Abdul Karim

Secretion of pro-oncogenic AGR2 protein in cancer.

Heliyon

Avec: Nurshahirah Ashikin Moidu , Nisa Syakila A Rahman , Saiful Effendi Syafruddin , Teck Yew Low , M Aiman Mohtar

Corrigendum: VHL-Mediated Regulation of CHCHD4 and Mitochondrial Function.

Frontiers in oncology

Avec: Thomas Briston , Jenna M Stephen , Luke W Thomas , Cinzia Esposito , Yuen-Li Chung , Saiful E Syafruddin , Mark Turmaine , Lucas A Maddalena , Basma Greef , Gyorgy Szabadkai , Patrick H Maxwell , Sakari Vanharanta , Margaret Ashcroft

Short open reading frames (sORFs) and microproteins: an update on their identification and validation measures.

Journal of biomedical science

Avec: Alyssa Zi-Xin Leong , Pey Yee Lee , M Aiman Mohtar , Saiful Effendi Syafruddin , Yuh-Fen Pung , Teck Yew Low

The renal lineage factor PAX8 controls oncogenic signalling in kidney cancer.

Nature

Avec: Saroor A Patel , Shoko Hirosue , Paulo Rodrigues , Erika Vojtasova , Emma K Richardson , Jianfeng Ge , Saiful E Syafruddin , Alyson Speed , Evangelia K Papachristou , David Baker , David Clarke , Stephenie Purvis , Ludovic Wesolowski , Anna Dyas , Leticia Castillon , Veronica Caraffini , Dóra Bihary , Cissy Yong , David J Harrison , Grant D Stewart , Mitchell J Machiela , Mark P Purdue , Stephen J Chanock , Anne Y Warren , Shamith A Samarajiwa , Jason S Carroll , Sakari Vanharanta

Reverting

Cells

Avec: Asmaa Y Abuhamad , Nurul Nadia Mohamad Zamberi , Ling Sheen , Safaa M Naes , Siti Nur Hasanah Mohd Yusuf , Asilah Ahmad Tajudin , M Aiman Mohtar , Amir Syahir Amir Hamzah , Saiful Effendi Syafruddin

Insights into the molecular mechanisms and signalling pathways of epithelial to mesenchymal transition (EMT) in colorectal cancer: A systematic review and bioinformatic analysis of gene expression.

Gene

Avec: Suha Azizan , Kim Jun Cheng , Elsa Haniffah Mejia Mohamed , Kamariah Ibrahim , Farid Nazer Faruqu , Kumutha Malar Vellasamy , Tak Loon Khong , Saiful Effendi Syafruddin , Zaridatul Aini Ibrahim

Réseau de co-auteurs

Saiful Effendi Syafruddin 24 collaborations

M Aiman Mohtar 14 collaborations

Teck Yew Low 8 collaborations

Azizah Ugusman 4 collaborations

Nurul Nadia Mohamad Zamberi 4 collaborations

Sakari Vanharanta 4 collaborations

Wan Fahmi Wan Mohamad Nazarie 3 collaborations

Nisa Syakila A Rahman 3 collaborations

Mohd Helmy Mokhtar 3 collaborations

Asmaa Y Abuhamad 3 collaborations

Elsa Haniffah Mejia Mohamed 3 collaborations

Zaridatul Aini Ibrahim 3 collaborations

Marjanu Hikmah Elias 3 collaborations

Abdul Kadir Abdul Karim 3 collaborations

Mohd Faizal Ahmad 3 collaborations

Muhiddin Ishak 2 collaborations

Sazuita Saidin 2 collaborations

Nurul-Syakima Ab Mutalib 2 collaborations

Yuh-Fen Pung 2 collaborations

Shahidee Zainal Abidin 2 collaborations

Adila A Hamid 2 collaborations

Siti Nur Hasanah Mohd Yusuf 2 collaborations

Farid Nazer Faruqu 2 collaborations

Kumutha Malar Vellasamy 2 collaborations

Kamariah Ibrahim 2 collaborations

Syazalina Zahari 2 collaborations

Nurunnajah Lazim 2 collaborations

Zulazmi Sutaji 2 collaborations

Mohammad Azrai Abu 2 collaborations

Nurshahirah Ashikin Moidu 2 collaborations

Kim Jun Cheng 2 collaborations

Poh Kuan Wong 2 collaborations

Fook Choe Cheah 2 collaborations

Norazrina Azmi 2 collaborations

Eng Wee Chua 2 collaborations

Paulo Rodrigues 2 collaborations

Erika Vojtasova 2 collaborations

Saroor A Patel 2 collaborations

Anne Y Warren 2 collaborations

Grant D Stewart 2 collaborations

Dóra Bihary 2 collaborations

Shamith A Samarajiwa 2 collaborations

Rashidah Baharudin 1 collaboration

Azliana Muhamad Yusof 1 collaboration

Learn-Han Lee 1 collaboration

Adaikkalam Vellaichamy 1 collaboration

Chris Soon Heng Tan 1 collaboration

Nurul Iffah Mohd Isa 1 collaboration

Farah Hanan Fathihah Jaffar 1 collaboration

Kelly Xue Jing Jong 1 collaboration

Malak Hassn Mesrati 1 collaboration

Amir Syahir 1 collaboration

Mohd Firdaus-Raih 1 collaboration

Siti Nurmi Nasir 1 collaboration

Bee Hong Soon 1 collaboration

Ryia Illani Mohd Yunos 1 collaboration

Jia-Shiun Khoo 1 collaboration

Francis Yew Fu Tieng 1 collaboration

Najwa Farhah Md Yusof 1 collaboration

Mohd Ridhwan Abd Razak 1 collaboration

Norshahidah Mahamad Nadzir 1 collaboration

Nadiah Abu 1 collaboration

Isa Md Rose 1 collaboration

Ismail Sagap 1 collaboration

Luqman Mazlan 1 collaboration

Rahman Jamal 1 collaboration

Nur Syakirah Othman 1 collaboration

Amilia Aminuddin 1 collaboration

Norfilza Mohd Mokhtar 1 collaboration

Jaya Kumar 1 collaboration

Jia Xian Law 1 collaboration

M Nazhif Zaini 1 collaboration

Johanna Burge 1 collaboration

Tim Eisen 1 collaboration

Sheen Ling 1 collaboration

Pei Yuen Ng 1 collaboration

Ahmad Mohd Faizal 1 collaboration

Norazilah Mat Jin 1 collaboration

Muhammad Azrai Abu 1 collaboration

Ani Amelia Zainuddin 1 collaboration

Nao Suzuki 1 collaboration

Thomas Briston 1 collaboration

Jenna M Stephen 1 collaboration

Luke W Thomas 1 collaboration

Cinzia Esposito 1 collaboration

Yuen-Li Chung 1 collaboration

Mark Turmaine 1 collaboration

Lucas A Maddalena 1 collaboration

Basma Greef 1 collaboration

Gyorgy Szabadkai 1 collaboration

Patrick H Maxwell 1 collaboration

Margaret Ashcroft 1 collaboration

Alyssa Zi-Xin Leong 1 collaboration

Pey Yee Lee 1 collaboration

Shoko Hirosue 1 collaboration

Emma K Richardson 1 collaboration

Jianfeng Ge 1 collaboration

Alyson Speed 1 collaboration

Evangelia K Papachristou 1 collaboration

David Baker 1 collaboration

David Clarke 1 collaboration

Stephenie Purvis 1 collaboration

Ludovic Wesolowski 1 collaboration

Anna Dyas 1 collaboration

Leticia Castillon 1 collaboration

Veronica Caraffini 1 collaboration

Cissy Yong 1 collaboration

David J Harrison 1 collaboration

Mitchell J Machiela 1 collaboration

Mark P Purdue 1 collaboration

Stephen J Chanock 1 collaboration

Jason S Carroll 1 collaboration

Ling Sheen 1 collaboration

Safaa M Naes 1 collaboration

Asilah Ahmad Tajudin 1 collaboration

Amir Syahir Amir Hamzah 1 collaboration

Suha Azizan 1 collaboration

Tak Loon Khong 1 collaboration