Shiho Fujisaka

Affiliations

First Department of Internal Medicine, University of Toyama, 2630 Sugitani, Toyama-shi, Toyama 930-0194, Japan.

Publications (32)

Isoxanthohumol, a hop-derived flavonoid, alters the metabolomics profile of mouse feces.

Bioscience of microbiota, food and health

Avec: Shinya Fukizawa , Mai Yamashita , Shiho Fujisaka , Kazuyuki Tobe , Yuji Nonaka , Norihito Murayama

Type 1 diabetes woman with repeated miscarriages successfully gave birth after introducing an insulin pump with a predictive low glucose suspend feature.

Diabetology international

Avec: Hisae Honoki , Kunimasa Yagi , Sayaka Tsuda , Tsutomu Wada , Asako Enkaku , Maki Nakagawa-Yokoyama , Miki Kamigishi , Masataka Shikata , Akiko Takikawa-Nishiday , Shiho Fujisaka , Daisuke Chujo , Toshiyasu Sasaoka , Akitoshi Nakashima , Shigeru Saito , Kazuyuki Tobe

Fate of adipocyte progenitors during adipogenesis in mice fed a high-fat diet.

Molecular metabolism

Avec: Muhammad Bilal , Allah Nawaz , Tomonobu Kado , Muhammad Rahil Aslam , Yoshiko Igarashi , Ayumi Nishimura , Yoshiyuki Watanabe , Takahide Kuwano , Jianhui Liu , Hiroyuki Miwa , Takumi Era , Koichi Ikuta , Johji Imura , Kunimasa Yagi , Takashi Nakagawa , Shiho Fujisaka , Kazuyuki Tobe

Perioperative C-peptide index is associated with the status of diabetes management after pancreatectomy.

Journal of diabetes investigation

Avec: Masataka Shikata , Daisuke Chujo , Asako Enkaku , Akiko Takikawa-Nishida , Hisae Honoki , Shinnosuke Yamada-Matsukoshi , Maki Nakagawa-Yokoyama , Miki Kamigishi , Shinya Inagawa , Shiho Fujisaka , Kunimasa Yagi , Kazuto Shibuya , Tsutomu Fujii , Kazuyuki Tobe

Depletion of CD206

Nature communications

Avec: Allah Nawaz , Muhammad Bilal , Shiho Fujisaka , Tomonobu Kado , Muhammad Rahil Aslam , Saeed Ahmed , Keisuke Okabe , Yoshiko Igarashi , Yoshiyuki Watanabe , Takahide Kuwano , Koichi Tsuneyama , Ayumi Nishimura , Yasuhiro Nishida , Seiji Yamamoto , Masakiyo Sasahara , Johji Imura , Hisashi Mori , Martin M Matzuk , Fujimi Kudo , Ichiro Manabe , Akiyoshi Uezumi , Takashi Nakagawa , Yumiko Oishi , Kazuyuki Tobe

Impact of Vancomycin Treatment and Gut Microbiota on Bile Acid Metabolism and the Development of Non-Alcoholic Steatohepatitis in Mice.

International journal of molecular sciences

Avec: Kaichi Kasai , Naoya Igarashi , Yuki Tada , Koudai Kani , Shun Takano , Tsutomu Yanagibashi , Fumitake Usui-Kawanishi , Shiho Fujisaka , Shiro Watanabe , Mayuko Ichimura-Shimizu , Kiyoshi Takatsu , Kazuyuki Tobe , Koichi Tsuneyama , Yukihiro Furusawa , Yoshinori Nagai

Gut microbiota, determined by dietary nutrients, drive modification of the plasma lipid profile and insulin resistance.

iScience

Avec: Yoshiyuki Watanabe , Shiho Fujisaka , Kazutaka Ikeda , Masaki Ishikawa , Takahiro Yamada , Allah Nawaz , Tomonobu Kado , Takahide Kuwano , Ayumi Nishimura , Muhammad Bilal , Jianhui Liu , Kunimasa Yagi , Koji Hase , Kazuyuki Tobe

Generation and characterization of a Meflin-CreERT2 transgenic line for lineage tracing in white adipose tissue.

PloS one

Avec: Takahide Kuwano , Hironori Izumi , Muhammad Rahil Aslam , Yoshiko Igarashi , Muhammad Bilal , Ayumi Nishimura , Yoshiyuki Watanabe , Allah Nawaz , Tomonobu Kado , Koichi Ikuta , Seiji Yamamoto , Masakiyo Sasahara , Shiho Fujisaka , Kunimasa Yagi , Hisashi Mori , Kazuyuki Tobe

Isoxanthohumol improves obesity and glucose metabolism via inhibiting intestinal lipid absorption with a bloom of Akkermansia muciniphila in mice.

Molecular metabolism

Avec: Yoshiyuki Watanabe , Shiho Fujisaka , Yoshitomo Morinaga , Shiro Watanabe , Allah Nawaz , Hideki Hatta , Tomonobu Kado , Ayumi Nishimura , Muhammad Bilal , Muhammad Rahil Aslam , Keiko Honda , Yoshimi Nakagawa , Samir Softic , Kenichi Hirabayashi , Takashi Nakagawa , Yoshinori Nagai , Kazuyuki Tobe

Increased Number of Mucosal-Associated Invariant T Cells Is Associated with the Inhibition of Nonalcoholic Fatty Liver Disease in High Fat Diet-Fed Mice.

International journal of molecular sciences

Avec: Haruka Kishi , Isao Usui , Teruo Jojima , Shiho Fujisaka , Sho Wakamatsu , Yuiko Mizunuma-Inoue , Takafumi Niitani , Shintaro Sakurai , Toshie Iijima , Takuya Tomaru , Kazuyuki Tobe , Yoshimasa Aso

Fructose induced KHK-C can increase ER stress independent of its effect on lipogenesis to drive liver disease in diet-induced and genetic models of NAFLD.

Metabolism: clinical and experimental

Avec: Se-Hyung Park , Robert N Helsley , Taghreed Fadhul , Jennifer L S Willoughby , Leila Noetzli , Ho-Chou Tu , Marie H Solheim , Shiho Fujisaka , Hui Pan , Jonathan M Dreyfuss , Joanna Bons , Jacob Rose , Christina D King , Birgit Schilling , Aldons J Lusis , Calvin Pan , Manoj Gupta , Rohit N Kulkarni , Kevin Fitzgerald , Philip A Kern , Senad Divanovic , C Ronald Kahn , Samir Softic

Bofutsushosan improves gut barrier function with a bloom of Akkermansia muciniphila and improves glucose metabolism in mice with diet-induced obesity.

Scientific reports

Avec: Shiho Fujisaka , Isao Usui , Allah Nawaz , Yoshiko Igarashi , Keisuke Okabe , Yukihiro Furusawa , Shiro Watanabe , Seiji Yamamoto , Masakiyo Sasahara , Yoshiyuki Watanabe , Yoshinori Nagai , Kunimasa Yagi , Takashi Nakagawa , Kazuyuki Tobe

Macrophage-specific hypoxia-inducible factor-1α deletion suppresses the development of liver tumors in high-fat diet-fed obese and diabetic mice.

Journal of diabetes investigation

Avec: Akiko Takikawa , Isao Usui , Shiho Fujisaka , Koichi Tsuneyama , Keisuke Okabe , Takashi Nakagawa , Allah Nawaz , Tomonobu Kado , Teruo Jojima , Yoshimasa Aso , Yoshihiro Hayakawa , Kunikimi Yagi , Kazuyuki Tobe

Heterogeneity of adipose tissue-resident macrophages-beyond M1/M2 paradigm.

Diabetology international

Avec: Allah Nawaz , Shiho Fujisaka , Tomonobu Kado , Ishtiaq Jeelani , Kazuyuki Tobe

Fructose Induced KHK-C Increases ER Stress and Modulates Hepatic Transcriptome to Drive Liver Disease in Diet-Induced and Genetic Models of NAFLD.

bioRxiv : the preprint server for biology

Dietary Sugars Alter Hepatic Fatty Acid Oxidation via Transcriptional and Post-translational Modifications of Mitochondrial Proteins.

Cell metabolism

Avec: Samir Softic , Jesse G Meyer , Guo-Xiao Wang , Manoj K Gupta , Thiago M Batista , Hans P M M Lauritzen , Shiho Fujisaka , Dolors Serra , Laura Herrero , Jennifer Willoughby , Kevin Fitzgerald , Olga Ilkayeva , Christopher B Newgard , Bradford W Gibson , Birgit Schilling , David E Cohen , C Ronald Kahn

The gut microbiome: a core regulator of metabolism.

The Journal of endocrinology

Avec: Shiho Fujisaka , Yoshiyuki Watanabe , Kazuyuki Tobe

Negative correlation between organ heteroplasmy, particularly hepatic heteroplasmy, and age at death revealed by post-mortem studies of m.3243A > G cases.

Molecular genetics and metabolism

Avec: Kunimasa Yagi , Satoko Okazaki , Azusa Ohbatake , Masako Nakaya , Jianhui Liu , Eiko Arite , Yukiko Miyamoto , Naoko Ito , Kaoru Nakano , Naoto Yamaaki , Hisae Honoki , Shiho Fujisaka , Daisuke Chujo , Shin-Ichiro Tsunoda , Kunio Yanagimoto , Tsuyoshi Nozue , Masayo Yamada , Kotaro Ooe , Tsutomu Araki , Akikatsu Nakashima , Yasushi Azami , Yukio Sodemoto , Kenichi Tadokoro , Makoto Nagano , Tohru Noguchi , Atushi Nohara , Hideki Origasa , Yo Niida , Hayato Tada

Deep Learning of Cancer Stem Cell Morphology Using Conditional Generative Adversarial Networks.

Biomolecules

Avec: Saori Aida , Junpei Okugawa , Serena Fujisaka , Tomonari Kasai , Hiroyuki Kameda , Tomoyasu Sugiyama

Anti-obesity effect of a hop-derived prenylflavonoid isoxanthohumol in a high-fat diet-induced obese mouse model.

Bioscience of microbiota, food and health

Avec: Shinya Fukizawa , Mai Yamashita , Ken-Ichi Wakabayashi , Shiho Fujisaka , Kazuyuki Tobe , Yuji Nonaka , Norihito Murayama

Clinical manifestations of a sporadic maturity-onset diabetes of the young (MODY) 5 with a whole deletion of HNF1B based on 17q12 microdeletion.

Endocrine journal

Avec: Yoshiyuki Omura , Kunimasa Yagi , Hisae Honoki , Minoru Iwata , Asako Enkaku , Akiko Takikawa , Takahide Kuwano , Yoshiyuki Watanabe , Ayumi Nishimura , Jianhui Liu , Daisuke Chujo , Shiho Fujisaka , Mayumi Enya , Yukio Horikawa , Kazuyuki Tobe

Diastolic Cardiac Function Improvement by Liraglutide Is Mainly Body Weight Reduction Dependent but Independently Contributes to B-Type Natriuretic Peptide Reduction in Patients with Type 2 Diabetes with Preserved Ejection Fraction.

Journal of diabetes research

Avec: Kunimasa Yagi , Teruhiko Imamura , Hayato Tada , Daisuke Chujo , Jianhui Liu , Yuuki Shima , Azusa Ohbatake , Yukiko Miyamoto , Satoko Okazaki , Naoko Ito , Kaoru Nakano , Masataka Shikata , Asako Enkaku , Akiko Takikawa , Hisae Honoki , Shiho Fujisaka , Hideki Origasa , Kazuyuki Tobe

High prevalence of fragmented QRS on electrocardiography in Japanese patients with diabetes irrespective of metabolic syndrome.

Journal of diabetes investigation

Avec: Kunimasa Yagi , Yoshiki Nagata , Takashi Yamagami , Daisuke Chujo , Miki Kamigishi , Maki Yokoyama-Nakagawa , Masataka Shikata , Asako Enkaku , Akiko Takikawa-Nishida , Hisae Honoki , Shiho Fujisaka , Hideki Origasa , Kazuyuki Tobe

The role of adipose tissue M1/M2 macrophages in type 2 diabetes mellitus.

Diabetology international

Avec: Shiho Fujisaka

Astaxanthin stimulates mitochondrial biogenesis in insulin resistant muscle via activation of AMPK pathway.

Journal of cachexia, sarcopenia and muscle

Avec: Yasuhiro Nishida , Allah Nawaz , Tomonobu Kado , Akiko Takikawa , Yoshiko Igarashi , Yasuhiro Onogi , Tsutomu Wada , Toshiyasu Sasaoka , Seiji Yamamoto , Masakiyo Sasahara , Johji Imura , Kumpei Tokuyama , Isao Usui , Takashi Nakagawa , Shiho Fujisaka , Yagi Kunimasa , Kazuyuki Tobe

Astaxanthin, a Marine Carotenoid, Maintains the Tolerance and Integrity of Adipose Tissue and Contributes to Its Healthy Functions.

Nutrients

Avec: Allah Nawaz , Yasuhiro Nishida , Akiko Takikawa , Shiho Fujisaka , Tomonobu Kado , Aminuddin Aminuddin , Muhammad Bilal , Ishtiaq Jeelani , Muhammad Rahil Aslam , Ayumi Nishimura , Takahide Kuwano , Yoshiyuki Watanabe , Yoshiko Igarashi , Keisuke Okabe , Saeed Ahmed , Azhar Manzoor , Isao Usui , Kunimasa Yagi , Takashi Nakagawa , Kazuyuki Tobe

Fragmented QRS on electrocardiography as a predictor for diastolic cardiac dysfunction in type 2 diabetes.

Journal of diabetes investigation

Avec: Kunimasa Yagi , Teruhiko Imamura , Hayato Tada , Jianhui Liu , Yukiko Miyamoto , Azusa Ohbatake , Naoko Ito , Masataka Shikata , Asako Enkaku , Akiko Takikawa , Hisae Honoki , Shiho Fujisaka , Daisuke Chujo , Hideki Origasa , Koichiro Kinugawa , Kazuyuki Tobe

Gut Microbiota Regulate Pancreatic Growth, Exocrine Function, and Gut Hormones.

Diabetes

Avec: Khyati Girdhar , Marion Soto , Qian Huang , Lucie Orliaguet , Carly Cederquist , Bharathi Sundaresh , Jiang Hu , Maximilian Figura , Amol Raisingani , Emanuel E Canfora , Ercument Dirice , Shiho Fujisaka , Gijs H Goossens , Ellen E Blaak , Rohit N Kulkarni , C Ronald Kahn , Emrah Altindis

Isoliquiritigenin Attenuates Adipose Tissue Inflammation and Metabolic Syndrome by Modifying Gut Bacteria Composition in Mice.

Molecular nutrition & food research

Avec: Riko Ishibashi , Yukihiro Furusawa , Hiroe Honda , Yasuharu Watanabe , Shiho Fujisaka , Miyu Nishikawa , Shinichi Ikushiro , Shin Kurihara , Yoshiaki Tabuchi , Kazuyuki Tobe , Kiyoshi Takatsu , Yoshinori Nagai

A New Method for Albuminuria Measurement Using a Specific Reaction between Albumin and the Luciferin of the Firefly Squid

International journal of molecular sciences

Avec: Tetsuya Ishimoto , Takuya Okada , Shiho Fujisaka , Kunimasa Yagi , Kazuyuki Tobe , Naoki Toyooka , Hisashi Mori

Short-term recovery of insulin secretion in response to a meal is associated with future glycemic control in type 2 diabetes patients.

Journal of diabetes investigation

Avec: Asako Enkaku , Daisuke Chujo , Miki Kamigishi , Shinya Inagawa , Shinnosuke Matsukoshi , Waka Sakai , Akiko Takikawa , Shiho Fujisaka , Kazuyuki Tobe

Identification of herbal drug extracts that promote growth of

Diabetology international

Avec: Shiho Fujisaka , Yoshiyuki Watanabe , Kazufumi Toume , Yoshitomo Morinaga , Allah Nawaz , Tomonobu Kado , Ayumi Nishimura , Muhammad Bilal , Muhammad Rahil Aslam , Yoshiko Igarashi , Yoshimi Nakagawa , Kazuyuki Tobe

Réseau de co-auteurs

Kazuyuki Tobe 25 collaborations

Kunimasa Yagi 13 collaborations

Allah Nawaz 11 collaborations

Tomonobu Kado 10 collaborations

Yoshiyuki Watanabe 10 collaborations

Daisuke Chujo 8 collaborations

Ayumi Nishimura 8 collaborations

Hisae Honoki 7 collaborations

Asako Enkaku 7 collaborations

Muhammad Bilal 7 collaborations

Yoshiko Igarashi 7 collaborations

Takashi Nakagawa 7 collaborations

Akiko Takikawa 7 collaborations

Muhammad Rahil Aslam 6 collaborations

Takahide Kuwano 6 collaborations

Jianhui Liu 6 collaborations

Masataka Shikata 5 collaborations

Isao Usui 5 collaborations

Miki Kamigishi 4 collaborations

Keisuke Okabe 4 collaborations

Seiji Yamamoto 4 collaborations

Masakiyo Sasahara 4 collaborations

Yoshinori Nagai 4 collaborations

Samir Softic 4 collaborations

C Ronald Kahn 4 collaborations

Hideki Origasa 4 collaborations

Johji Imura 3 collaborations

Koichi Tsuneyama 3 collaborations

Yasuhiro Nishida 3 collaborations

Hisashi Mori 3 collaborations

Shiro Watanabe 3 collaborations

Yukihiro Furusawa 3 collaborations

Birgit Schilling 3 collaborations

Rohit N Kulkarni 3 collaborations

Kevin Fitzgerald 3 collaborations

Azusa Ohbatake 3 collaborations

Yukiko Miyamoto 3 collaborations

Naoko Ito 3 collaborations

Hayato Tada 3 collaborations

Shinya Fukizawa 2 collaborations

Mai Yamashita 2 collaborations

Yuji Nonaka 2 collaborations

Norihito Murayama 2 collaborations

Tsutomu Wada 2 collaborations

Maki Nakagawa-Yokoyama 2 collaborations

Toshiyasu Sasaoka 2 collaborations

Koichi Ikuta 2 collaborations

Akiko Takikawa-Nishida 2 collaborations

Shinya Inagawa 2 collaborations

Saeed Ahmed 2 collaborations

Kiyoshi Takatsu 2 collaborations

Yoshitomo Morinaga 2 collaborations

Yoshimi Nakagawa 2 collaborations

Teruo Jojima 2 collaborations

Yoshimasa Aso 2 collaborations

Se-Hyung Park 2 collaborations

Robert N Helsley 2 collaborations

Taghreed Fadhul 2 collaborations

Jennifer L S Willoughby 2 collaborations

Leila Noetzli 2 collaborations

Ho-Chou Tu 2 collaborations

Marie H Solheim 2 collaborations

Hui Pan 2 collaborations

Jonathan M Dreyfuss 2 collaborations

Joanna Bons 2 collaborations

Jacob Rose 2 collaborations

Christina D King 2 collaborations

Aldons J Lusis 2 collaborations

Calvin Pan 2 collaborations

Manoj Gupta 2 collaborations

Philip A Kern 2 collaborations

Senad Divanovic 2 collaborations

Ishtiaq Jeelani 2 collaborations

Satoko Okazaki 2 collaborations

Kaoru Nakano 2 collaborations

Teruhiko Imamura 2 collaborations

Sayaka Tsuda 1 collaboration

Akiko Takikawa-Nishiday 1 collaboration

Akitoshi Nakashima 1 collaboration

Shigeru Saito 1 collaboration

Hiroyuki Miwa 1 collaboration

Takumi Era 1 collaboration

Shinnosuke Yamada-Matsukoshi 1 collaboration

Kazuto Shibuya 1 collaboration

Tsutomu Fujii 1 collaboration

Martin M Matzuk 1 collaboration

Fujimi Kudo 1 collaboration

Ichiro Manabe 1 collaboration

Akiyoshi Uezumi 1 collaboration

Yumiko Oishi 1 collaboration

Kaichi Kasai 1 collaboration

Naoya Igarashi 1 collaboration

Yuki Tada 1 collaboration

Koudai Kani 1 collaboration

Shun Takano 1 collaboration

Tsutomu Yanagibashi 1 collaboration

Fumitake Usui-Kawanishi 1 collaboration

Mayuko Ichimura-Shimizu 1 collaboration

Kazutaka Ikeda 1 collaboration

Masaki Ishikawa 1 collaboration

Takahiro Yamada 1 collaboration

Koji Hase 1 collaboration

Hironori Izumi 1 collaboration

Hideki Hatta 1 collaboration

Keiko Honda 1 collaboration

Kenichi Hirabayashi 1 collaboration

Haruka Kishi 1 collaboration

Sho Wakamatsu 1 collaboration

Yuiko Mizunuma-Inoue 1 collaboration

Takafumi Niitani 1 collaboration

Shintaro Sakurai 1 collaboration

Toshie Iijima 1 collaboration

Takuya Tomaru 1 collaboration

Yoshihiro Hayakawa 1 collaboration

Kunikimi Yagi 1 collaboration

Jesse G Meyer 1 collaboration

Guo-Xiao Wang 1 collaboration

Manoj K Gupta 1 collaboration

Thiago M Batista 1 collaboration

Hans P M M Lauritzen 1 collaboration

Dolors Serra 1 collaboration

Laura Herrero 1 collaboration

Jennifer Willoughby 1 collaboration

Olga Ilkayeva 1 collaboration

Christopher B Newgard 1 collaboration

Bradford W Gibson 1 collaboration

David E Cohen 1 collaboration

Masako Nakaya 1 collaboration

Eiko Arite 1 collaboration

Naoto Yamaaki 1 collaboration

Shin-Ichiro Tsunoda 1 collaboration

Kunio Yanagimoto 1 collaboration

Tsuyoshi Nozue 1 collaboration

Masayo Yamada 1 collaboration

Kotaro Ooe 1 collaboration

Tsutomu Araki 1 collaboration

Akikatsu Nakashima 1 collaboration

Yasushi Azami 1 collaboration

Yukio Sodemoto 1 collaboration

Kenichi Tadokoro 1 collaboration

Makoto Nagano 1 collaboration

Tohru Noguchi 1 collaboration

Atushi Nohara 1 collaboration

Yo Niida 1 collaboration

Saori Aida 1 collaboration

Junpei Okugawa 1 collaboration

Serena Fujisaka 1 collaboration

Tomonari Kasai 1 collaboration

Hiroyuki Kameda 1 collaboration

Tomoyasu Sugiyama 1 collaboration

Ken-Ichi Wakabayashi 1 collaboration

Yoshiyuki Omura 1 collaboration

Minoru Iwata 1 collaboration

Mayumi Enya 1 collaboration

Yukio Horikawa 1 collaboration

Yuuki Shima 1 collaboration

Yoshiki Nagata 1 collaboration

Takashi Yamagami 1 collaboration

Maki Yokoyama-Nakagawa 1 collaboration

Yasuhiro Onogi 1 collaboration

Kumpei Tokuyama 1 collaboration

Yagi Kunimasa 1 collaboration

Aminuddin Aminuddin 1 collaboration

Azhar Manzoor 1 collaboration

Koichiro Kinugawa 1 collaboration

Khyati Girdhar 1 collaboration

Marion Soto 1 collaboration

Qian Huang 1 collaboration

Lucie Orliaguet 1 collaboration

Carly Cederquist 1 collaboration

Bharathi Sundaresh 1 collaboration

Jiang Hu 1 collaboration

Maximilian Figura 1 collaboration

Amol Raisingani 1 collaboration

Emanuel E Canfora 1 collaboration

Ercument Dirice 1 collaboration

Gijs H Goossens 1 collaboration

Ellen E Blaak 1 collaboration

Emrah Altindis 1 collaboration

Riko Ishibashi 1 collaboration

Hiroe Honda 1 collaboration

Yasuharu Watanabe 1 collaboration

Miyu Nishikawa 1 collaboration

Shinichi Ikushiro 1 collaboration

Shin Kurihara 1 collaboration

Yoshiaki Tabuchi 1 collaboration

Tetsuya Ishimoto 1 collaboration

Takuya Okada 1 collaboration

Naoki Toyooka 1 collaboration

Shinnosuke Matsukoshi 1 collaboration

Waka Sakai 1 collaboration

Kazufumi Toume 1 collaboration