Shozo Ohtsuki

Affiliations

Department of Biopharmaceutics and Drug Metabolism, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan.

Publications (29)

Clinical outcomes after the endovascular treatments of pulmonary vein stenosis in patients with congenital heart disease.

Cardiology in the young

Avec: Yoshihiko Kurita , Kenji Baba , Maiko Kondo , Takahiro Eitoku , Shingo Kasahara , Tatsuo Iwasaki , Shinichi Ohtsuki , Hirokazu Tsukahara

Proteomic analysis of small intestinal epithelial cells in antibiotic-treated mice: Changes in drug transporters and metabolizing enzymes.

Drug metabolism and pharmacokinetics

Avec: Takuya Kuno , Mio Hirayama-Kurogi , Shingo Ito , Sumio Ohtsuki

Novel cyclic peptides facilitating transcellular blood-brain barrier transport of macromolecules in vitro and in vivo.

Journal of controlled release : official journal of the Controlled Release Society

Avec: Shunsuke Yamaguchi , Shingo Ito , Takeshi Masuda , Pierre-Olivier Couraud , Sumio Ohtsuki

Identification of a Specific Translational Machinery via TCTP-EF1A2 Interaction Regulating NF1-associated Tumor Growth by Affinity Purification and Data-independent Mass Spectrometry Acquisition (AP-DIA).

Molecular & cellular proteomics : MCP

Avec: Daiki Kobayashi , Takaho Tokuda , Kyosuke Sato , Hiroki Okanishi , Megumi Nagayama , Mio Hirayama-Kurogi , Sumio Ohtsuki , Norie Araki

Critical contribution of macrophage scavenger receptor 1 to the uptake of nanostructured DNA by immune cells.

Nanomedicine : nanotechnology, biology, and medicine

Avec: Keisuke Umemura , Shozo Ohtsuki , Makoto Nagaoka , Kosuke Kusamori , Takao Inoue , Yuki Takahashi , Yoshinobu Takakura , Makiya Nishikawa

Diurnal Changes in Protein Expression at the Blood-Brain Barrier in Mice.

Biological & pharmaceutical bulletin

Avec: Seiryo Ogata , Shingo Ito , Takeshi Masuda , Sumio Ohtsuki

Deficiency of the CD155-CD96 immune checkpoint controls IL-9 production in giant cell arteritis.

Cell reports. Medicine

Avec: Shozo Ohtsuki , Chenyao Wang , Ryu Watanabe , Hui Zhang , Mitsuhiro Akiyama , Melanie C Bois , Joseph J Maleszewski , Kenneth J Warrington , Gerald J Berry , Jörg J Goronzy , Cornelia M Weyand

Logistics and distribution of small extracellular vesicles from the subcutaneous space to the lymphatic system.

Journal of controlled release : official journal of the Controlled Release Society

Avec: Yu Sakurai , Asa Ohtani , Yuka Nakayama , Masaki Gomi , Takeshi Masuda , Sumio Ohtsuki , Hiroki Tanaka , Hidetaka Akita

A multi-center randomized controlled trial to investigate potential effects of exercise therapy on renal function stratified by renal disorders and renal pathology: beneficial or harmful effect in immunoglobulin a nephropathy.

Clinical and experimental nephrology

Avec: Takahide Kimura , Naoki Washida , Shigeaki Ohtsuki , Kazuya Sugita , Kozi Hosoya , Kiyotaka Uchiyama

Tumor cell-derived ANGPTL2 promotes β-catenin-driven intestinal tumorigenesis.

Oncogene

Avec: Haruki Horiguchi , Tsuyoshi Kadomatsu , Shinsei Yumoto , Takeshi Masuda , Keishi Miyata , Shuji Yamamura , Michio Sato , Jun Morinaga , Sumio Ohtsuki , Hideo Baba , Toshiro Moroishi , Yuichi Oike

The transcription factor RFX5 coordinates antigen-presenting function and resistance to nutrient stress in synovial macrophages.

Nature metabolism

Avec: Zhaolan Hu , Tuantuan V Zhao , Tao Huang , Shozo Ohtsuki , Ke Jin , Isabel N Goronzy , Bowen Wu , Matthew P Abdel , Jacob W Bettencourt , Gerald J Berry , Jörg J Goronzy , Cornelia M Weyand

Hyperactivity of the CD155 immune checkpoint suppresses anti-viral immunity in patients with coronary artery disease.

Nature cardiovascular research

Avec: Tuantuan V Zhao , Zhaolan Hu , Shozo Ohtsuki , Ke Jin , Bowen Wu , Gerald J Berry , Robert L Frye , Jörg J Goronzy , Cornelia M Weyand

SETD1A function in leukemia is mediated through interaction with mitotic regulators BuGZ/BUB3.

EMBO reports

Avec: Sarah Perlee , Sota Kikuchi , Tomoyoshi Nakadai , Takeshi Masuda , Sumio Ohtsuki , Makoto Matsumoto , Bahityar Rahmutulla , Masaki Fukuyo , Paolo Cifani , Alex Kentsis , Robert G Roeder , Atsushi Kaneda , Takayuki Hoshii

Identification of Cell-Surface Proteins Endocytosed by Human Brain Microvascular Endothelial Cells In Vitro.

Pharmaceutics

Avec: Shingo Ito , Mariko Oishi , Seiryo Ogata , Tatsuki Uemura , Pierre-Olivier Couraud , Takeshi Masuda , Sumio Ohtsuki

Effects of differences in pre-analytical processing on blood protein profiles determined with SWATH-MS.

Journal of proteomics

Avec: Madoka Nambu , Shin Nishiumi , Takashi Kobayashi , Takeshi Masuda , Shingo Ito , Masaru Yoshida , Sumio Ohtsuki

Targeted Proteomics-Based Quantitative Protein Atlas of Pannexin and Connexin Subtypes in Mouse and Human Tissues and Cancer Cell Lines.

Journal of pharmaceutical sciences

Avec: Masanori Tachikawa , Yosuke Kaneko , Sumio Ohtsuki , Yasuo Uchida , Michitoshi Watanabe , Hideo Ohtsuka , Tetsuya Terasaki

Cyclization of Single-Chain Fv Antibodies Markedly Suppressed Their Characteristic Aggregation Mediated by Inter-Chain VH-VL Interactions.

Molecules (Basel, Switzerland)

Avec: Soichiro Yamauchi , Yoshihiro Kobashigawa , Natsuki Fukuda , Manaka Teramoto , Yuya Toyota , Chenjiang Liu , Yuka Ikeguchi , Takashi Sato , Yuko Sato , Hiroshi Kimura , Takeshi Masuda , Sumio Ohtsuki , Kentaro Noi , Teru Ogura , Hiroshi Morioka

Involvement of Claudin-11 in Disruption of Blood-Brain, -Spinal Cord, and -Arachnoid Barriers in Multiple Sclerosis.

Molecular neurobiology

Avec: Yasuo Uchida , Tomohito Sumiya , Masanori Tachikawa , Tatsuya Yamakawa , Sho Murata , Yuta Yagi , Kazuki Sato , Alice Stephan , Katsuaki Ito , Sumio Ohtsuki , Pierre-Olivier Couraud , Takashi Suzuki , Tetsuya Terasaki

Advances in sample preparation for membrane proteome quantification.

Drug discovery today. Technologies

Avec: Takeshi Masuda , Shingo Ito , Sumio Ohtsuki

Innate and Adaptive Immunity in Giant Cell Arteritis.

Frontiers in immunology

Avec: Mitsuhiro Akiyama , Shozo Ohtsuki , Gerald J Berry , David H Liang , Jörg J Goronzy , Cornelia M Weyand

Cardiosphere-derived exosomal microRNAs for myocardial repair in pediatric dilated cardiomyopathy.

Science translational medicine

Avec: Kenta Hirai , Daiki Ousaka , Yosuke Fukushima , Maiko Kondo , Takahiro Eitoku , Yusuke Shigemitsu , Mayuko Hara , Kenji Baba , Tatsuo Iwasaki , Shingo Kasahara , Shinichi Ohtsuki , Hidemasa Oh

Efficacy of Wearable Device Gait Training on Parkinson's Disease: A Randomized Controlled Open-label Pilot Study.

Internal medicine (Tokyo, Japan)

Avec: Noriko Kawashima , Kazuko Hasegawa , Masako Iijima , Kayo Nagami , Tomomi Makimura , Aya Kumon , Shigeaki Ohtsuki

Proteomic alterations in the brain and blood-brain barrier during brain Aβ accumulation in an APP knock-in mouse model of Alzheimer's disease.

Fluids and barriers of the CNS

Avec: Shingo Ito , Ryotaro Yagi , Seiryo Ogata , Takeshi Masuda , Takashi Saito , Takaomi Saido , Sumio Ohtsuki

Influence of MDR1 gene polymorphism (2677G>T) on expression and function of P-glycoprotein at the blood-brain barrier: utilizing novel P-glycoprotein humanized mice with mutation.

Pharmacogenetics and genomics

Avec: Yuki Yamasaki , Takashi Moriwaki , Seiryo Ogata , Shingo Ito , Sumio Ohtsuki , Genki Minegishi , Satoshi Abe , Yumi Ohta , Kanako Kazuki , Kaoru Kobayashi , Yasuhiro Kazuki

Aging-associated HELIOS deficiency in naive CD4

Nature immunology

Avec: Huimin Zhang , Rohit R Jadhav , Wenqiang Cao , Isabel N Goronzy , Tuantuan V Zhao , Jun Jin , Shozo Ohtsuki , Zhaolan Hu , Jose Morales , William J Greenleaf , Cornelia M Weyand , Jörg J Goronzy

Insulin receptor at the blood-brain barrier: Transport and signaling.

Vitamins and hormones

Avec: Sumio Ohtsuki

Matrix mechanotransduction mediated by thrombospondin-1/integrin/YAP in the vascular remodeling.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Yoshito Yamashiro , Bui Quoc Thang , Karina Ramirez , Seung Jae Shin , Tomohiro Kohata , Shigeaki Ohata , Tram Anh Vu Nguyen , Sumio Ohtsuki , Kazuaki Nagayama , Hiromi Yanagisawa

Gelsolin inhibits malignant phenotype of glioblastoma and is regulated by miR-654-5p and miR-450b-5p.

Cancer science

Avec: Jiakang Zhang , Takuya Furuta , Hemragul Sabit , Sho Tamai , Shabierjiang Jiapaer , Yu Dong , Masashi Kinoshita , Yasuo Uchida , Sumio Ohtsuki , Tetsuya Terasaki , Shiguang Zhao , Mitsutoshi Nakada

Convenient method of producing cyclic single-chain Fv antibodies by split-intein-mediated protein ligation and chaperone co-expression.

Journal of biochemistry

Avec: Chenjiang Liu , Yoshihiro Kobashigawa , Soichiro Yamauchi , Natsuki Fukuda , Takashi Sato , Takeshi Masuda , Sumio Ohtsuki , Hiroshi Morioka

Réseau de co-auteurs

Sumio Ohtsuki 19 collaborations

Takeshi Masuda 11 collaborations

Shingo Ito 8 collaborations

Jörg J Goronzy 5 collaborations

Cornelia M Weyand 5 collaborations

Seiryo Ogata 4 collaborations

Gerald J Berry 4 collaborations

Pierre-Olivier Couraud 3 collaborations

Zhaolan Hu 3 collaborations

Tuantuan V Zhao 3 collaborations

Yasuo Uchida 3 collaborations

Tetsuya Terasaki 3 collaborations

Kenji Baba 2 collaborations

Maiko Kondo 2 collaborations

Takahiro Eitoku 2 collaborations

Shingo Kasahara 2 collaborations

Tatsuo Iwasaki 2 collaborations

Shinichi Ohtsuki 2 collaborations

Mio Hirayama-Kurogi 2 collaborations

Mitsuhiro Akiyama 2 collaborations

Shigeaki Ohtsuki 2 collaborations

Ke Jin 2 collaborations

Isabel N Goronzy 2 collaborations

Bowen Wu 2 collaborations

Masanori Tachikawa 2 collaborations

Soichiro Yamauchi 2 collaborations

Yoshihiro Kobashigawa 2 collaborations

Natsuki Fukuda 2 collaborations

Chenjiang Liu 2 collaborations

Takashi Sato 2 collaborations

Hiroshi Morioka 2 collaborations

Yoshihiko Kurita 1 collaboration

Hirokazu Tsukahara 1 collaboration

Takuya Kuno 1 collaboration

Shunsuke Yamaguchi 1 collaboration

Daiki Kobayashi 1 collaboration

Takaho Tokuda 1 collaboration

Kyosuke Sato 1 collaboration

Hiroki Okanishi 1 collaboration

Megumi Nagayama 1 collaboration

Norie Araki 1 collaboration

Keisuke Umemura 1 collaboration

Makoto Nagaoka 1 collaboration

Kosuke Kusamori 1 collaboration

Takao Inoue 1 collaboration

Yuki Takahashi 1 collaboration

Yoshinobu Takakura 1 collaboration

Makiya Nishikawa 1 collaboration

Chenyao Wang 1 collaboration

Ryu Watanabe 1 collaboration

Hui Zhang 1 collaboration

Melanie C Bois 1 collaboration

Joseph J Maleszewski 1 collaboration

Kenneth J Warrington 1 collaboration

Yu Sakurai 1 collaboration

Asa Ohtani 1 collaboration

Yuka Nakayama 1 collaboration

Masaki Gomi 1 collaboration

Hiroki Tanaka 1 collaboration

Hidetaka Akita 1 collaboration

Takahide Kimura 1 collaboration

Naoki Washida 1 collaboration

Kazuya Sugita 1 collaboration

Kozi Hosoya 1 collaboration

Kiyotaka Uchiyama 1 collaboration

Haruki Horiguchi 1 collaboration

Tsuyoshi Kadomatsu 1 collaboration

Shinsei Yumoto 1 collaboration

Keishi Miyata 1 collaboration

Shuji Yamamura 1 collaboration

Michio Sato 1 collaboration

Jun Morinaga 1 collaboration

Hideo Baba 1 collaboration

Toshiro Moroishi 1 collaboration

Yuichi Oike 1 collaboration

Tao Huang 1 collaboration

Matthew P Abdel 1 collaboration

Jacob W Bettencourt 1 collaboration

Robert L Frye 1 collaboration

Sarah Perlee 1 collaboration

Sota Kikuchi 1 collaboration

Tomoyoshi Nakadai 1 collaboration

Makoto Matsumoto 1 collaboration

Bahityar Rahmutulla 1 collaboration

Masaki Fukuyo 1 collaboration

Paolo Cifani 1 collaboration

Alex Kentsis 1 collaboration

Robert G Roeder 1 collaboration

Atsushi Kaneda 1 collaboration

Takayuki Hoshii 1 collaboration

Mariko Oishi 1 collaboration

Tatsuki Uemura 1 collaboration

Madoka Nambu 1 collaboration

Shin Nishiumi 1 collaboration

Takashi Kobayashi 1 collaboration

Masaru Yoshida 1 collaboration

Yosuke Kaneko 1 collaboration

Michitoshi Watanabe 1 collaboration

Hideo Ohtsuka 1 collaboration

Manaka Teramoto 1 collaboration

Yuya Toyota 1 collaboration

Yuka Ikeguchi 1 collaboration

Yuko Sato 1 collaboration

Hiroshi Kimura 1 collaboration

Kentaro Noi 1 collaboration

Teru Ogura 1 collaboration

Tomohito Sumiya 1 collaboration

Tatsuya Yamakawa 1 collaboration

Sho Murata 1 collaboration

Yuta Yagi 1 collaboration

Kazuki Sato 1 collaboration

Alice Stephan 1 collaboration

Katsuaki Ito 1 collaboration

Takashi Suzuki 1 collaboration

David H Liang 1 collaboration

Kenta Hirai 1 collaboration

Daiki Ousaka 1 collaboration

Yosuke Fukushima 1 collaboration

Yusuke Shigemitsu 1 collaboration

Mayuko Hara 1 collaboration

Hidemasa Oh 1 collaboration

Noriko Kawashima 1 collaboration

Kazuko Hasegawa 1 collaboration

Masako Iijima 1 collaboration

Kayo Nagami 1 collaboration

Tomomi Makimura 1 collaboration

Aya Kumon 1 collaboration

Ryotaro Yagi 1 collaboration

Takashi Saito 1 collaboration

Takaomi Saido 1 collaboration

Yuki Yamasaki 1 collaboration

Takashi Moriwaki 1 collaboration

Genki Minegishi 1 collaboration

Satoshi Abe 1 collaboration

Yumi Ohta 1 collaboration

Kanako Kazuki 1 collaboration

Kaoru Kobayashi 1 collaboration

Yasuhiro Kazuki 1 collaboration

Huimin Zhang 1 collaboration

Rohit R Jadhav 1 collaboration

Wenqiang Cao 1 collaboration

Jun Jin 1 collaboration

Jose Morales 1 collaboration

William J Greenleaf 1 collaboration

Yoshito Yamashiro 1 collaboration

Bui Quoc Thang 1 collaboration

Karina Ramirez 1 collaboration

Seung Jae Shin 1 collaboration

Tomohiro Kohata 1 collaboration

Shigeaki Ohata 1 collaboration

Tram Anh Vu Nguyen 1 collaboration

Kazuaki Nagayama 1 collaboration

Hiromi Yanagisawa 1 collaboration

Jiakang Zhang 1 collaboration

Takuya Furuta 1 collaboration

Hemragul Sabit 1 collaboration

Sho Tamai 1 collaboration

Shabierjiang Jiapaer 1 collaboration

Yu Dong 1 collaboration

Masashi Kinoshita 1 collaboration

Shiguang Zhao 1 collaboration

Mitsutoshi Nakada 1 collaboration