questionsmedicales.fr
Techniques d'investigation
Techniques de chimie analytique
Chromatographie
Chromatographie en phase liquide
Chromatographie en phase liquide : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Chromatographie
Analyse de sang
Échantillons biologiques
Analyse de tissus
Toxines
Analyse de contaminants
Symptômes
5
Déséquilibres hormonaux
Symptômes endocriniens
Maladies métaboliques
Métabolites
Intoxication médicamenteuse
Symptômes
Prévention
5
Prévention des maladies
Biomarqueurs
Dépistage précoce
Diabète
Santé publique
Surveillance des maladies
Intoxications alimentaires
Contaminants
Recherche en santé publique
Épidémiologie
Traitements
5
Surveillance thérapeutique
Médicaments
Ajustement de traitement
Concentration de médicaments
Efficacité du traitement
Biomarqueurs
Traitements du cancer
Maladies infectieuses
Effets secondaires
Métabolites
Complications
5
Erreurs d'analyse
Diagnostics erronés
Effets indésirables
Méthodes analytiques
Échantillonnage
Infection
Protocoles de laboratoire
Manipulation des échantillons
Résultats erronés
Complications cliniques
Facteurs de risque
5
Facteurs de risque
Qualité des échantillons
Habitudes alimentaires
Métabolites
Médicaments
Interférences
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"name": "Comment la chromatographie en phase liquide est-elle utilisée en diagnostic ?",
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"text": "Elle permet d'analyser des échantillons biologiques pour détecter des substances spécifiques."
}
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{
"@type": "Question",
"name": "Quels types d'échantillons peuvent être analysés ?",
"position": 2,
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"@type": "Question",
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"position": 3,
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"text": "Elle offre une haute résolution et une grande sensibilité pour détecter des analytes."
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"@type": "Question",
"name": "Peut-on utiliser cette technique pour des médicaments ?",
"position": 4,
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"@type": "Question",
"name": "La chromatographie peut-elle aider à diagnostiquer des allergies ?",
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"text": "Oui, elle peut identifier des allergènes dans des échantillons biologiques."
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"name": "Quels symptômes sont liés à des déséquilibres hormonaux ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Fatigue, changements de poids, et irrégularités menstruelles peuvent être des indicateurs."
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"name": "Peut-on détecter des maladies métaboliques avec cette technique ?",
"position": 9,
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"text": "Oui, elle permet d'analyser des métabolites pour diagnostiquer des maladies métaboliques."
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"name": "Quels symptômes peuvent indiquer une intoxication médicamenteuse ?",
"position": 10,
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"name": "Comment la chromatographie contribue-t-elle à la prévention des maladies ?",
"position": 11,
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"text": "Elle permet de détecter précocement des biomarqueurs de maladies, facilitant l'intervention."
}
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"@type": "Question",
"name": "Peut-on utiliser cette technique pour le dépistage précoce ?",
"position": 12,
"acceptedAnswer": {
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"text": "Oui, elle est utilisée pour le dépistage de maladies comme le diabète et le cancer."
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"name": "Quels programmes de santé publique utilisent la chromatographie ?",
"position": 13,
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"text": "Des programmes de dépistage des drogues et de surveillance des maladies infectieuses."
}
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"@type": "Question",
"name": "La chromatographie peut-elle aider à prévenir les intoxications ?",
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"name": "Comment cette technique aide-t-elle à la recherche en santé publique ?",
"position": 15,
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"text": "Elle permet d'analyser des échantillons pour étudier l'épidémiologie des maladies."
}
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"@type": "Question",
"name": "La chromatographie en phase liquide est-elle utilisée dans le traitement ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Indirectement, elle aide à surveiller les niveaux de médicaments dans le sang."
}
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"@type": "Question",
"name": "Comment cette technique aide-t-elle à ajuster les traitements ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle permet de mesurer la concentration des médicaments pour optimiser les doses."
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"@type": "Question",
"name": "Peut-on utiliser la chromatographie pour évaluer l'efficacité d'un traitement ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle permet de quantifier les biomarqueurs et les médicaments dans le corps."
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"@type": "Question",
"name": "Quels traitements peuvent être surveillés par cette méthode ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements pour le cancer, les maladies infectieuses et les troubles psychiatriques."
}
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"@type": "Question",
"name": "La chromatographie peut-elle aider à détecter des effets secondaires ?",
"position": 20,
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"text": "Oui, elle peut identifier des métabolites associés à des effets indésirables."
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"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des risques d'infection ou de complications liées à la collecte d'échantillons biologiques."
}
},
{
"@type": "Question",
"name": "Comment minimiser les complications lors de l'analyse ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "En suivant des protocoles stricts de manipulation et d'analyse des échantillons."
}
},
{
"@type": "Question",
"name": "Les résultats erronés peuvent-ils entraîner des complications cliniques ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des résultats incorrects peuvent mener à des traitements inappropriés et à des complications."
}
},
{
"@type": "Question",
"name": "Quels facteurs de risque influencent l'analyse par chromatographie ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "La qualité des échantillons, la technique utilisée et l'expérience de l'opérateur."
}
},
{
"@type": "Question",
"name": "L'âge peut-il être un facteur de risque pour certaines analyses ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines maladies sont plus fréquentes chez les personnes âgées, influençant les résultats."
}
},
{
"@type": "Question",
"name": "Les habitudes alimentaires affectent-elles les résultats ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'alimentation peut influencer les niveaux de métabolites détectés dans les échantillons."
}
},
{
"@type": "Question",
"name": "Le mode de vie peut-il impacter les résultats d'analyse ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le tabagisme, l'alcool et d'autres facteurs de mode de vie peuvent affecter les résultats."
}
},
{
"@type": "Question",
"name": "Les médicaments pris peuvent-ils influencer les résultats ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certains médicaments peuvent interférer avec les analyses et fausser les résultats."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 13/03/2025
Contenu vérifié selon les dernières recommandations médicales
7 publications dans cette catégorie
Affiliations :
Biothermodynamics, TUM School of Life Sciences Weihenstephan, Technical University of Munich, Maximus-von-Imhof-Forum 2, 85354 Freising, Germany. Electronic address: mirjana.minceva@tum.de.
4 publications dans cette catégorie
Affiliations :
Biothermodynamics, TUM School of Life Sciences, Technical University of Munich, 85354 Freising, Germany.
Publications dans "Chromatographie en phase liquide" :
4 publications dans cette catégorie
Affiliations :
Biothermodynamics, TUM School of Life Sciences, Technical University of Munich, 85354 Freising, Germany.
Publications dans "Chromatographie en phase liquide" :
3 publications dans cette catégorie
Affiliations :
College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, 310032, China. Electronic address: sqtong@zjut.edu.cn.
Publications dans "Chromatographie en phase liquide" :
3 publications dans cette catégorie
Affiliations :
Department of Chemical Engineering, Vrije Universiteit Brussel, Pleinlaan 2, B-1050 Brussel, Belgium.
Publications dans "Chromatographie en phase liquide" :
3 publications dans cette catégorie
Affiliations :
Department of Analytical Chemistry, University of Valencia, c/Dr. Moliner 50, Burjassot, Spain.
Publications dans "Chromatographie en phase liquide" :
3 publications dans cette catégorie
Affiliations :
Department of Analytical Chemistry, University of Valencia, c/Dr. Moliner 50, Burjassot, Spain. Electronic address: celia.garcia@uv.es.
Publications dans "Chromatographie en phase liquide" :
2 publications dans cette catégorie
Publications dans "Chromatographie en phase liquide" :
2 publications dans cette catégorie
Affiliations :
College of Pharmaceutical Science, Zhejiang University of Technology, Chaowang Road 18, Chaohui No. 6 District, Hangzhou, 310032, China.
Publications dans "Chromatographie en phase liquide" :
2 publications dans cette catégorie
Affiliations :
Biothermodynamics, TUM School of Life Sciences Weihenstephan, Technical University of Munich, Maximus-von-Imhof-Forum 2, 85354 Freising, Germany.
Publications dans "Chromatographie en phase liquide" :
2 publications dans cette catégorie
Affiliations :
Advachrom, P.O. Box 1243, Wilmington, DE 19801, USA. Electronic address: leon@advachrom.com.
Publications dans "Chromatographie en phase liquide" :
2 publications dans cette catégorie
Affiliations :
Univ. Lille, CHU Lille, Inserm, Institut Pasteur de Lille, U1167 - Risk factors and molecular determinants of aging-related diseases, F-59000 Lille, France. Electronic address: emmanuelle.lipka@univ-lille.fr.
Publications dans "Chromatographie en phase liquide" :
2 publications dans cette catégorie
Affiliations :
Separation Science Group, Department of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281-S4, B-9000 Ghent, Belgium.
Publications dans "Chromatographie en phase liquide" :
2 publications dans cette catégorie
Affiliations :
Separation Science Group, Department of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281-S4, B-9000 Ghent, Belgium.
Publications dans "Chromatographie en phase liquide" :
2 publications dans cette catégorie
Affiliations :
Department of Chemistry, University of "La Sapienza", Rome, Italy.
Publications dans "Chromatographie en phase liquide" :
2 publications dans cette catégorie
Affiliations :
Department of Chemistry, University of "La Sapienza", Rome, Italy.
Publications dans "Chromatographie en phase liquide" :
2 publications dans cette catégorie
Affiliations :
Istituto per i Sistemi Biologici (ISB), CNR - Consiglio Nazionale delle Ricerche, Montelibretti, Rome, Italy.
Publications dans "Chromatographie en phase liquide" :
2 publications dans cette catégorie
Affiliations :
Department of Analytical Chemistry, University of Valencia, c/Dr. Moliner 50, Burjassot, Spain.
Publications dans "Chromatographie en phase liquide" :
2 publications dans cette catégorie
Affiliations :
Department of Analytical Chemistry, University of Valencia, c/Dr. Moliner 50, Burjassot, Spain.
Publications dans "Chromatographie en phase liquide" :
2 publications dans cette catégorie
Affiliations :
Waters Corporation, 34 Maple Street, Milford, MA 01757, USA. Electronic address: Martin_Gilar@waters.com.
Publications dans "Chromatographie en phase liquide" :
This Position Statement on root resorption represents the consensus of an expert committee convened by the European Society of Endodontology (ESE). The statement is based on current clinical and scien...
The current literature on multiple idiopathic cervical root resorption (MICRR), a rare and aggressive form of external root resorption, is limited to case reports and series. Therefore, we performed a...
This study aimed to understand the influence of periodontal fibroblasts (PDLFs) on clastic differentiation of macrophages (Mφ) in different resorptive environments....
PDLF-Mφ direct coculture (juxtacrine) was seeded on dentin, cementum, and polystyrene with/without lipopolysaccharide, macrophage colony-stimulating factor, and receptor activator of nuclear factor ka...
PDLF-Mφ coculture showed a higher number of TRAP-positive multinucleated cells than Mφ monoculture on dentin and polystyrene. No TRAP-positive multinucleated cells were observed in paracrine and cemen...
The study highlights the juxtacrine effect of PDLFs on the clastic differentiation of Mφ with a difference in clastic activity between dentin and cementum. The study also emphasizes the temporal effec...
The literature reports the association of external root resorption (ERR) with orthodontic movement. In cases of premolars extractions, orthodontic movement of anterior teeth is usually quite expressiv...
The aim of this study was to assess the root morphology of maxillary canines and incisors in patients submitted to four premolar extraction and orthodontic retraction of the anterior teeth, by means o...
The sample consisted of six adult patients, five female and one male, with a mean age of 23.5 ± 6.5 years, who underwent orthodontic treatment. All patients presented bimaxillary dental protrusion, wi...
All average differences were close to zero and, even when evaluating the extreme values, the observed changes were always smaller than the accuracy of the CBCT....
A mild resorption trend was observed, although it was not clinically significant, with values lower than the tomography accuracy....
External inflammatory root resorption (EIRR) and external replacement root resorption (ERRR) are the most common adverse outcomes after luxation injuries or dental injuries. They are usually detected ...
An a priori protocol was prepared by a multidisciplinary expert group, as per the Cochrane handbook and PRISMA guidelines. The systematic search was conducted in six databases and grey-literature sour...
Eight studies were included in the systematic review and could be categorized as per the source of biomarkers, namely epithelial cells from mucosa, gingival crevicular fluid and extracted teeth. The s...
Among the three sources, the inflammatory gingival crevicular fluid appeared to be the most non-invasive source of biomarkers for predicting trauma-induced root resorption, although the evidence about...
Class II malocclusion treatment efficiency with maxillary premolar extractions has been reported. However, no study evaluated the root resorption associated with this protocol. Therefore, this study a...
The sample consisted of 56 patients with complete Class II malocclusion, divided into 2 groups. Group 1 comprised 28 patients (10 female, 18 male) treated with maxillary first premolar extractions, an...
Overjet, overbite, inclination, vertical positional changes, and vertical and horizontal apical displacements of maxillary incisors were similar between groups. There was no statistically significant ...
Treating complete Class II malocclusion with 2 maxillary premolar extractions resulted in a similar root resorption as treating without maxillary premolar extractions. An individualized evaluation of ...
External apical root resorption (EARR) is a common undesirable outcome of orthodontic treatment, this study aimed to identify genetic polymorphisms associated with the susceptibility to extreme orthod...
Genomic DNA was isolated from the saliva of 77 patients who underwent orthodontic treatment involving two maxillary premolar extractions. The patients were divided into two groups based on EARR values...
SNPs related to genes TNFSF11, TNFRSF11B, WNT3A, SFRP2, LRP6, P2RX7, and LRP1 were found to be significantly associated with severe EARR (p < 0.05, pre-Bonferroni correction p-values). Additionally, t...
Extreme phenotype analysis has identified eleven SNPs related to genes TNFSF11, TNFRSF11B, WNT3A, SFRP2, LRP6, P2RX7, and LRP1 that are associated with severe root resorption in the Korean population....
The aim of this study was to estimate the prevalence and severity of external root resorption (RR) caused by retained third molars (M3), to compare the sensitivity of panoramic radiography (PAN) and c...
In a retrospective cross-sectional analysis, we included patients (N = 367) who underwent PAN and CBCT imaging between December 2017 and July 2019. Previous orthodontic treatment, age, gender, superim...
While less than 5% of PANs suggested RR associated with M3, CBCT showed RR in 20% of all M2 with adjacent retained M3. The angle of inclination of M3, patient age and vertical level of molar contact e...
Within the limitations of our study, these data confirm the poor performance of PAN in the diagnosis of RR. CBCT may be helpful in detecting RR in mesioangulated and deeply retained M3 in elderly pati...
Our study may help to decide whether CBCT should be considered prior to M3 surgery....
This study aimed to analyze the scientific production of genetic polymorphisms and external apical root resorption (EARR) to establish main findings, geographic trends, and research gaps for possible ...
Unrestricted publications were searched using the Scopus database (March 2023) to include studies that addressed the association between genetic polymorphisms and EARR. Case-control, cohort, cross-sec...
Of the 44 studies analyzed, "Iglesias-Linares A" was the most cited author. The University of Seville (Spain) conducted the most research on this topic. Brazil, Spain, and the USA were the leading cou...
Endodontics is an area of research that should focus more on root resorption and genetic polymorphisms, as it still underexplored, compared to orthodontics. Polymorphisms have been studied as possible...
External root resorption (ERR) has a multifactorial etiology and is difficult to diagnose, which means that is continues to be of research interest. This work mainly aims to determine whether external...
The Checklist for Reporting In-vitro Studies (CRIS) guidelines were followed throughout this study. This experiment highlights the preparation and generation of standardized synthetic teeth measured o...
ICC values for intra- and inter-examiner agreement were appropriate. DPR overestimated ERR detection compared to the actual and CBCT measurements [Mean diff = 0.765 and 0.768, respectively]. CBCT diag...
The results of this study highlight that both CBCT and DPR are good diagnostic methods for ERR. Nevertheless, root canal filling material influences diagnostic capability in ERR. The clinical signific...