Titre : Système digestif

Système digestif : Questions médicales fréquentes

Termes MeSH sélectionnés :

Cross-Over Studies

Questions fréquentes et termes MeSH associés

Diagnostic 5

#1

Comment diagnostiquer une maladie digestive ?

Un diagnostic peut inclure des examens cliniques, des analyses de sang et des imageries.
Maladies digestives Diagnostic médical
#2

Quels tests sont utilisés pour le reflux gastro-œsophagien ?

Les tests incluent la pH-métrie, l'endoscopie et la manométrie œsophagienne.
Reflux gastro-œsophagien Endoscopie
#3

Quelles sont les méthodes d'imagerie pour le système digestif ?

Les méthodes incluent l'échographie, la tomodensitométrie et l'IRM.
Imagerie médicale Système digestif
#4

Comment détecter une infection intestinale ?

Des analyses de selles et des cultures bactériennes sont souvent réalisées.
Infections intestinales Analyses de selles
#5

Quels marqueurs sanguins indiquent une maladie hépatique ?

Les transaminases, la bilirubine et l'albumine sont des marqueurs clés.
Maladies hépatiques Tests sanguins

Symptômes 5

#1

Quels sont les symptômes d'une gastrite ?

Les symptômes incluent des douleurs abdominales, des nausées et des vomissements.
Gastrite Symptômes
#2

Comment reconnaître une colite ?

Les signes incluent des douleurs abdominales, des diarrhées et des saignements.
Colite Diarrhée
#3

Quels symptômes indiquent une appendicite ?

Douleur abdominale, nausées, vomissements et fièvre sont des indicateurs.
Appendicite Symptômes
#4

Quels signes d'alerte pour une pancréatite ?

Douleurs abdominales sévères, nausées et vomissements fréquents sont alarmants.
Pancréatite Douleur abdominale
#5

Quels symptômes d'une maladie cœliaque ?

Les symptômes incluent des douleurs abdominales, des ballonnements et de la diarrhée.
Maladie cœliaque Symptômes

Prévention 5

#1

Comment prévenir les maladies digestives ?

Une alimentation équilibrée, l'hydratation et l'exercice régulier aident à prévenir.
Prévention Santé digestive
#2

Quelles habitudes alimentaires pour éviter le reflux ?

Éviter les aliments gras, épicés et les repas copieux aide à prévenir le reflux.
Reflux gastro-œsophagien Habitudes alimentaires
#3

Comment réduire le risque de cancer colorectal ?

Un régime riche en fibres, l'exercice et des dépistages réguliers sont recommandés.
Cancer colorectal Prévention
#4

Quelles mesures pour éviter les infections intestinales ?

Se laver les mains, cuire les aliments correctement et éviter l'eau contaminée sont essentiels.
Infections intestinales Hygiène
#5

Comment prévenir la constipation ?

Une alimentation riche en fibres et une hydratation adéquate aident à prévenir la constipation.
Constipation Prévention

Traitements 5

#1

Quels traitements pour le reflux gastro-œsophagien ?

Les traitements incluent des médicaments, des changements alimentaires et parfois la chirurgie.
Reflux gastro-œsophagien Traitements
#2

Comment traiter une infection intestinale ?

Le traitement peut inclure des antibiotiques et des réhydratations.
Infections intestinales Antibiotiques
#3

Quelles options pour la maladie de Crohn ?

Les options incluent des médicaments anti-inflammatoires et des interventions chirurgicales.
Maladie de Crohn Traitements
#4

Comment traiter une gastrite chronique ?

Le traitement peut comprendre des médicaments antiacides et des changements alimentaires.
Gastrite Médicaments antiacides
#5

Quels traitements pour les calculs biliaires ?

Les traitements incluent des médicaments, des changements alimentaires et parfois la chirurgie.
Calculs biliaires Chirurgie

Complications 5

#1

Quelles complications de la maladie de Crohn ?

Les complications incluent des fistules, des obstructions intestinales et des malnutritions.
Maladie de Crohn Complications
#2

Quels risques d'une appendicite non traitée ?

Une appendicite non traitée peut entraîner une péritonite et des infections graves.
Appendicite Péritonite
#3

Quelles complications du reflux gastro-œsophagien ?

Les complications incluent l'œsophagite, les sténoses et le cancer de l'œsophage.
Reflux gastro-œsophagien Complications
#4

Quels dangers d'une colite ulcéreuse ?

Les dangers incluent des saignements, des perforations et un risque accru de cancer colorectal.
Colite ulcéreuse Complications
#5

Quelles complications des calculs biliaires ?

Les complications peuvent inclure des infections, des pancréatites et des obstructions biliaires.
Calculs biliaires Complications

Facteurs de risque 5

#1

Quels facteurs de risque pour le cancer colorectal ?

Les facteurs incluent l'âge, les antécédents familiaux et un régime pauvre en fibres.
Cancer colorectal Facteurs de risque
#2

Quels risques liés à l'obésité pour le système digestif ?

L'obésité augmente le risque de reflux gastro-œsophagien et de maladies hépatiques.
Obésité Système digestif
#3

Comment le tabagisme affecte-t-il le système digestif ?

Le tabagisme augmente le risque de maladies digestives, y compris le cancer de l'œsophage.
Tabagisme Système digestif
#4

Quels facteurs de risque pour les maladies hépatiques ?

Les facteurs incluent la consommation excessive d'alcool, l'obésité et les hépatites virales.
Maladies hépatiques Facteurs de risque
#5

Quels risques liés à une alimentation riche en graisses ?

Une alimentation riche en graisses augmente le risque de maladies digestives et de calculs biliaires.
Alimentation Maladies digestives
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Electronic address: lwl512@zjgsu.edu.cn." } }, { "@type": "Person", "name": "Rosario Martín-Orti", "url": "https://questionsmedicales.fr/author/Rosario%20Mart%C3%ADn-Orti", "affiliation": { "@type": "Organization", "name": "Departamento de Anatomía y Embriología, Sección Departamental de Anatomía y Embriología (Veterinaria), Facultad de Veterinaria, Universidad Complutense, Avenida Puerta de Hierro s/n, 28040 Madrid, Spain." } }, { "@type": "Person", "name": "Carlos Tostado-Marcos", "url": "https://questionsmedicales.fr/author/Carlos%20Tostado-Marcos", "affiliation": { "@type": "Organization", "name": "Fundación Mundo Marino. Av. X 157, San Clemente del Tuyú B7105, Provincia de Buenos Aires, Argentina." } }, { "@type": "Person", "name": "Juan-Pablo Loureiro", "url": "https://questionsmedicales.fr/author/Juan-Pablo%20Loureiro", "affiliation": { "@type": "Organization", "name": "Fundación Mundo Marino. Av. 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"Symptômes", "headline": "Symptômes sur Système digestif", "description": "Quels sont les symptômes d'une gastrite ?\nComment reconnaître une colite ?\nQuels symptômes indiquent une appendicite ?\nQuels signes d'alerte pour une pancréatite ?\nQuels symptômes d'une maladie cœliaque ?", "url": "https://questionsmedicales.fr/mesh/D004064?mesh_terms=Cross-Over+Studies#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Système digestif", "description": "Comment prévenir les maladies digestives ?\nQuelles habitudes alimentaires pour éviter le reflux ?\nComment réduire le risque de cancer colorectal ?\nQuelles mesures pour éviter les infections intestinales ?\nComment prévenir la constipation ?", "url": "https://questionsmedicales.fr/mesh/D004064?mesh_terms=Cross-Over+Studies#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Système digestif", "description": "Quels traitements pour le reflux gastro-œsophagien ?\nComment traiter une infection intestinale ?\nQuelles options pour la maladie de Crohn ?\nComment traiter une gastrite chronique ?\nQuels traitements pour les calculs biliaires ?", "url": "https://questionsmedicales.fr/mesh/D004064?mesh_terms=Cross-Over+Studies#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Système digestif", "description": "Quelles complications de la maladie de Crohn ?\nQuels risques d'une appendicite non traitée ?\nQuelles complications du reflux gastro-œsophagien ?\nQuels dangers d'une colite ulcéreuse ?\nQuelles complications des calculs biliaires ?", "url": "https://questionsmedicales.fr/mesh/D004064?mesh_terms=Cross-Over+Studies#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Système digestif", "description": "Quels facteurs de risque pour le cancer colorectal ?\nQuels risques liés à l'obésité pour le système digestif ?\nComment le tabagisme affecte-t-il le système digestif ?\nQuels facteurs de risque pour les maladies hépatiques ?\nQuels risques liés à une alimentation riche en graisses ?", "url": "https://questionsmedicales.fr/mesh/D004064?mesh_terms=Cross-Over+Studies#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment diagnostiquer une maladie digestive ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "Un diagnostic peut inclure des examens cliniques, des analyses de sang et des imageries." } }, { "@type": "Question", "name": "Quels tests sont utilisés pour le reflux gastro-œsophagien ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Les tests incluent la pH-métrie, l'endoscopie et la manométrie œsophagienne." } }, { "@type": "Question", "name": "Quelles sont les méthodes d'imagerie pour le système digestif ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Les méthodes incluent l'échographie, la tomodensitométrie et l'IRM." } }, { "@type": "Question", "name": "Comment détecter une infection intestinale ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Des analyses de selles et des cultures bactériennes sont souvent réalisées." } }, { "@type": "Question", "name": "Quels marqueurs sanguins indiquent une maladie hépatique ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "Les transaminases, la bilirubine et l'albumine sont des marqueurs clés." } }, { "@type": "Question", "name": "Quels sont les symptômes d'une gastrite ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Les symptômes incluent des douleurs abdominales, des nausées et des vomissements." } }, { "@type": "Question", "name": "Comment reconnaître une colite ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Les signes incluent des douleurs abdominales, des diarrhées et des saignements." } }, { "@type": "Question", "name": "Quels symptômes indiquent une appendicite ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Douleur abdominale, nausées, vomissements et fièvre sont des indicateurs." } }, { "@type": "Question", "name": "Quels signes d'alerte pour une pancréatite ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Douleurs abdominales sévères, nausées et vomissements fréquents sont alarmants." } }, { "@type": "Question", "name": "Quels symptômes d'une maladie cœliaque ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Les symptômes incluent des douleurs abdominales, des ballonnements et de la diarrhée." } }, { "@type": "Question", "name": "Comment prévenir les maladies digestives ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "Une alimentation équilibrée, l'hydratation et l'exercice régulier aident à prévenir." } }, { "@type": "Question", "name": "Quelles habitudes alimentaires pour éviter le reflux ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Éviter les aliments gras, épicés et les repas copieux aide à prévenir le reflux." } }, { "@type": "Question", "name": "Comment réduire le risque de cancer colorectal ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Un régime riche en fibres, l'exercice et des dépistages réguliers sont recommandés." } }, { "@type": "Question", "name": "Quelles mesures pour éviter les infections intestinales ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Se laver les mains, cuire les aliments correctement et éviter l'eau contaminée sont essentiels." } }, { "@type": "Question", "name": "Comment prévenir la constipation ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Une alimentation riche en fibres et une hydratation adéquate aident à prévenir la constipation." } }, { "@type": "Question", "name": "Quels traitements pour le reflux gastro-œsophagien ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Les traitements incluent des médicaments, des changements alimentaires et parfois la chirurgie." } }, { "@type": "Question", "name": "Comment traiter une infection intestinale ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "Le traitement peut inclure des antibiotiques et des réhydratations." } }, { "@type": "Question", "name": "Quelles options pour la maladie de Crohn ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "Les options incluent des médicaments anti-inflammatoires et des interventions chirurgicales." } }, { "@type": "Question", "name": "Comment traiter une gastrite chronique ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Le traitement peut comprendre des médicaments antiacides et des changements alimentaires." } }, { "@type": "Question", "name": "Quels traitements pour les calculs biliaires ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "Les traitements incluent des médicaments, des changements alimentaires et parfois la chirurgie." } }, { "@type": "Question", "name": "Quelles complications de la maladie de Crohn ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Les complications incluent des fistules, des obstructions intestinales et des malnutritions." } }, { "@type": "Question", "name": "Quels risques d'une appendicite non traitée ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Une appendicite non traitée peut entraîner une péritonite et des infections graves." } }, { "@type": "Question", "name": "Quelles complications du reflux gastro-œsophagien ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "Les complications incluent l'œsophagite, les sténoses et le cancer de l'œsophage." } }, { "@type": "Question", "name": "Quels dangers d'une colite ulcéreuse ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Les dangers incluent des saignements, des perforations et un risque accru de cancer colorectal." } }, { "@type": "Question", "name": "Quelles complications des calculs biliaires ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "Les complications peuvent inclure des infections, des pancréatites et des obstructions biliaires." } }, { "@type": "Question", "name": "Quels facteurs de risque pour le cancer colorectal ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "Les facteurs incluent l'âge, les antécédents familiaux et un régime pauvre en fibres." } }, { "@type": "Question", "name": "Quels risques liés à l'obésité pour le système digestif ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "L'obésité augmente le risque de reflux gastro-œsophagien et de maladies hépatiques." } }, { "@type": "Question", "name": "Comment le tabagisme affecte-t-il le système digestif ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "Le tabagisme augmente le risque de maladies digestives, y compris le cancer de l'œsophage." } }, { "@type": "Question", "name": "Quels facteurs de risque pour les maladies hépatiques ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Les facteurs incluent la consommation excessive d'alcool, l'obésité et les hépatites virales." } }, { "@type": "Question", "name": "Quels risques liés à une alimentation riche en graisses ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "Une alimentation riche en graisses augmente le risque de maladies digestives et de calculs biliaires." } } ] } ] }
Dr Olivier Menir

Contenu validé par Dr Olivier Menir

Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale


Validation scientifique effectuée le 27/04/2025

Contenu vérifié selon les dernières recommandations médicales

Sous-catégories

43 au total
└─

Voies biliaires

Biliary Tract D001659 - A03.159
└─

Tube digestif

Gastrointestinal Tract D041981 - A03.556
└─

Foie

Liver D008099 - A03.620
└─

Pancréas

Pancreas D010179 - A03.734
└─└─

Conduits biliaires

Bile Ducts D001652 - A03.159.183
└─└─

Vésicule biliaire

Gallbladder D005704 - A03.159.439
└─└─

Intestins

Intestines D007422 - A03.556.124
└─└─

Tube digestif inférieur

Lower Gastrointestinal Tract D041741 - A03.556.249
└─└─

Tube digestif supérieur

Upper Gastrointestinal Tract D041742 - A03.556.875
└─└─

Conduits biliaires intrahépatiques

Bile Ducts, Intrahepatic D001653 - A03.620.150
└─└─

Conduits pancréatiques

Pancreatic Ducts D010183 - A03.734.667
└─└─└─

Conduits biliaires extrahépatiques

Bile Ducts, Extrahepatic D017734 - A03.159.183.079
└─└─└─

Intestin grêle

Intestine, Small D007421 - A03.556.124.684
└─└─└─

Iléum

Ileum D007082 - A03.556.249.124
└─└─└─

Gros intestin

Intestine, Large D007420 - A03.556.249.249
└─└─└─

Jéjunum

Jejunum D007583 - A03.556.249.750
└─└─└─

Duodénum

Duodenum D004386 - A03.556.875.249
└─└─└─

Oesophage

Esophagus D004947 - A03.556.875.500
└─└─└─

Estomac

Stomach D013270 - A03.556.875.875
└─└─└─

Canalicules biliaires

Bile Canaliculi D001648 - A03.620.150.125
└─└─└─

Ampoule hépatopancréatique

Ampulla of Vater D014670 - A03.734.667.500
└─└─└─└─

Conduit cholédoque

Common Bile Duct D003135 - A03.159.183.079.300
└─└─└─└─

Conduit cystique

Cystic Duct D003549 - A03.159.183.079.450
└─└─└─└─

Conduit hépatique commun

Hepatic Duct, Common D006500 - A03.159.183.079.600
└─└─└─└─

Valvule iléocaecale

Ileocecal Valve D007080 - A03.556.249.124.400
└─└─└─└─

Canal anal

Anal Canal D001003 - A03.556.249.249.070
└─└─└─└─

Caecum

Cecum D002432 - A03.556.249.249.209
└─└─└─└─

Côlon

Colon D003106 - A03.556.249.249.356
└─└─└─└─

Rectum

Rectum D012007 - A03.556.249.249.767
└─└─└─└─

Glandes duodénales

Brunner Glands D002011 - A03.556.875.249.322
└─└─└─└─

Cardia

Cardia D002299 - A03.556.875.875.163
└─└─└─└─

Jonction oesogastrique

Esophagogastric Junction D004943 - A03.556.875.875.330
└─└─└─└─

Fundus gastrique

Gastric Fundus D005748 - A03.556.875.875.419
└─└─└─└─

Moignon gastrique

Gastric Stump D018530 - A03.556.875.875.578
└─└─└─└─

Antre pylorique

Pyloric Antrum D011706 - A03.556.875.875.716
└─└─└─└─

Pylore

Pylorus D011708 - A03.556.875.875.799
└─└─└─└─└─

Appendice vermiforme

Appendix D001065 - A03.556.249.249.209.290
└─└─└─└─└─

Côlon ascendant

Colon, Ascending D044682 - A03.556.249.249.356.333
└─└─└─└─└─

Côlon descendant

Colon, Descending D044683 - A03.556.249.249.356.500
└─└─└─└─└─

Côlon sigmoïde

Colon, Sigmoid D012809 - A03.556.249.249.356.668
└─└─└─└─└─

Côlon transverse

Colon, Transverse D044684 - A03.556.249.249.356.834
└─└─└─└─└─

Muscle sphincter de l'ampoule hépatopancréatique

Sphincter of Oddi D009803 - A03.556.875.249.160.572
└─└─└─└─└─

Sphincter inférieur de l'oesophage

Esophageal Sphincter, Lower D049630 - A03.556.875.875.330.350

Auteurs principaux

Jianzhong Han

3 publications dans cette catégorie

Affiliations :
  • School of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310018, PR China.

Weilin Liu

3 publications dans cette catégorie

Affiliations :
  • School of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310018, PR China. Electronic address: lwl512@zjgsu.edu.cn.

Rosario Martín-Orti

2 publications dans cette catégorie

Affiliations :
  • Departamento de Anatomía y Embriología, Sección Departamental de Anatomía y Embriología (Veterinaria), Facultad de Veterinaria, Universidad Complutense, Avenida Puerta de Hierro s/n, 28040 Madrid, Spain.
Publications dans "Système digestif" :

Carlos Tostado-Marcos

2 publications dans cette catégorie

Affiliations :
  • Fundación Mundo Marino. Av. X 157, San Clemente del Tuyú B7105, Provincia de Buenos Aires, Argentina.
Publications dans "Système digestif" :

Juan-Pablo Loureiro

2 publications dans cette catégorie

Affiliations :
  • Fundación Mundo Marino. Av. X 157, San Clemente del Tuyú B7105, Provincia de Buenos Aires, Argentina.
Publications dans "Système digestif" :

Ignacio Molpeceres-Diego

2 publications dans cette catégorie

Affiliations :
  • Fundación Mundo Marino. Av. X 157, San Clemente del Tuyú B7105, Provincia de Buenos Aires, Argentina.
Publications dans "Système digestif" :

Enrique Tendillo-Domínguez

2 publications dans cette catégorie

Affiliations :
  • Fundación Mundo Marino. Av. X 157, San Clemente del Tuyú B7105, Provincia de Buenos Aires, Argentina.
Publications dans "Système digestif" :

Inmaculada Santos-Álvarez

2 publications dans cette catégorie

Affiliations :
  • Departamento de Anatomía y Embriología, Sección Departamental de Anatomía y Embriología (Veterinaria), Facultad de Veterinaria, Universidad Complutense, Avenida Puerta de Hierro s/n, 28040 Madrid, Spain.
Publications dans "Système digestif" :

Pilar Pérez-Lloret

2 publications dans cette catégorie

Affiliations :
  • Departamento de Anatomía y Embriología, Sección Departamental de Anatomía y Embriología (Veterinaria), Facultad de Veterinaria, Universidad Complutense, Avenida Puerta de Hierro s/n, 28040 Madrid, Spain.
Publications dans "Système digestif" :

Juncal González-Soriano

2 publications dans cette catégorie

Affiliations :
  • Departamento de Anatomía y Embriología, Sección Departamental de Anatomía y Embriología (Veterinaria), Facultad de Veterinaria, Universidad Complutense, Avenida Puerta de Hierro s/n, 28040 Madrid, Spain.
Publications dans "Système digestif" :

Zhechuan Mei

2 publications dans cette catégorie

Affiliations :
  • The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Publications dans "Système digestif" :

Olivia Ménard

2 publications dans cette catégorie

Affiliations :
  • STLO, UMR 1253, INRA, Agrocampus Ouest, 35000 Rennes, France.
Publications dans "Système digestif" :

Didier Dupont

2 publications dans cette catégorie

Affiliations :
  • STLO, UMR 1253, INRA, Agrocampus Ouest, 35000 Rennes, France.
Publications dans "Système digestif" :

Lina Sun

1 publication dans cette catégorie

Affiliations :
  • Department of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University, 710061, Xi'an, Shaanxi, China.
  • Institute of Infection and Immunity, Xi'an Jiaotong University Health Science Center, Translational Medicine Institute, 710061, Xi'an, Shaanxi, China.
  • Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education, 710061, Xi'an, Shaanxi, China.
  • Xi'an Key Laboratory of Immune Related Diseases, 710061, Xi'an, Shannxi, China.
Publications dans "Système digestif" :

Baojun Zhang

1 publication dans cette catégorie

Affiliations :
  • Department of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University, 710061, Xi'an, Shaanxi, China. bj.zhang@mail.xjtu.edu.cn.
  • Institute of Infection and Immunity, Xi'an Jiaotong University Health Science Center, Translational Medicine Institute, 710061, Xi'an, Shaanxi, China. bj.zhang@mail.xjtu.edu.cn.
  • Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education, 710061, Xi'an, Shaanxi, China. bj.zhang@mail.xjtu.edu.cn.
  • Xi'an Key Laboratory of Immune Related Diseases, 710061, Xi'an, Shannxi, China. bj.zhang@mail.xjtu.edu.cn.
Publications dans "Système digestif" :

B Gavilán

1 publication dans cette catégorie

Affiliations :
  • Departament de Genètica, Microbiologia i Estadística, Universitat de Barcelona, Av. Diagonal 643, 08028, Barcelona, Spain.
Publications dans "Système digestif" :

S G Sprecher

1 publication dans cette catégorie

Affiliations :
  • Department of Biology, University of Fribourg, 10, ch. Du Musée, 1700, Fribourg, Switzerland.
Publications dans "Système digestif" :

V Hartenstein

1 publication dans cette catégorie

Affiliations :
  • Department of Biology, University of California, Los Angeles, CA, USA. volkerh@mcdb.ucla.edu.
Publications dans "Système digestif" :

P Martinez

1 publication dans cette catégorie

Affiliations :
  • Departament de Genètica, Microbiologia i Estadística, Universitat de Barcelona, Av. Diagonal 643, 08028, Barcelona, Spain. Pedro.martinez@ub.edu.
  • Institut Català de Recerca i Estudis Avançats (ICREA), Barcelona, Spain. Pedro.martinez@ub.edu.
Publications dans "Système digestif" :

Yuwei Ye

1 publication dans cette catégorie

Affiliations :
  • State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, China.
Publications dans "Système digestif" :

Sources (10000 au total)

Pharmacokinetic boosting of olaparib: A randomised, cross-over study (PROACTIVE-study).

Pharmacokinetic (PK) boosting is the intentional use of a drug-drug interaction to enhance systemic drug exposure. PK boosting of olaparib, a CYP3A-substrate, has the potential to reduce PK variabilit... This cross-over, multicentre trial compared olaparib 300 mg twice daily (BID) with olaparib 100 mg BID boosted with the strong CYP3A-inhibitor cobicistat 150 mg BID. Patients were randomised to the st... Of 15 included patients, 12 were eligible for PK analysis. The GMR of the AUC... Boosting a 100 mg BID olaparib dose with cobicistat increases olaparib exposure 1.45-fold, compared to the standard dose of 300 mg BID. Equivalence of the boosted olaparib was thus not established. Bo...

A randomized cross-over study of cryopreserved platelets in prophylactic transfusions of thrombocytopenic patients.

The short shelf-life of liquid-stored platelets (LP) at 20-24°C poses shortage and wastage challenges. Cryopreserved platelets have significantly extended shelf-life, and were safe and efficacious for... We performed a phase 1b/2a randomized cross-over study comparing the safety and efficacy of cryopreserved buffy coat-derived pooled platelets (CP) to LP in the prophylactic transfusions of thrombocyto... A total of 18 adults were randomly assigned 1:1 to CP and LP for their first thrombocytopenic period (TP) of up to 28-days. A total of 14 crossed over to the other platelet-arm for the second TP. Over... During shortages, CP may supplement LP in prophylactic transfusions of thrombocytopenic patients....

Webtool to enhance the accuracy of diagnostic algorithms for HFpEF: a prospective cross-over study.

Diagnosis of heart failure with preserved ejection fraction (HFpEF) can be challenging. This study aimed to evaluate the potential of a webtool to enhance the scoring accuracy when applying the comple... We developed an online tool, the HFpEF calculator, that enables the automatic calculation of current HFpEF algorithms. We assessed the accuracy of manual vs. automatic scoring, defined as the percenta... Manual calculation of HFpEF diagnostic algorithms is often inaccurate. Using an automated webtool to calculate HFpEF algorithms significantly improved correct scoring. This new approach may impact the...

Physical intradialytic patient-reported outcome measures in haemodialysis and haemodiafiltration: A cross-over study.

Standard haemodialysis (sHD) is associated with a poor survival and marked adverse intradialytic patient-reported outcome measures (ID-PROMs). Whereas physical ID-PROMs (PID-PROMs) are alleviated by c... To assess whether PID-PROMs and thermal perception differ between sHD, cHD, low volume HDF (lvHDF) and high volume HDF (hvHDF), 40 patients were cross-over randomized to each modality for 2 weeks. Dia... Except for the item 'feeling cold' during cHD (p = .01), PID-PROMs did not differ between modalities, but varied markedly between patients (11/13 items, p < .05). T... (1) PID-PROMs did not differ between modalities, but varied markedly between patients. Hence, PID-PROMs are largely patient-dependent. (2) While T...

Caution with competitive gamification in medical education: unexpected results of a randomised cross-over study.

To intrinsically motivate students in the long term, longitudinal e-learning systems combined with repeated testing and competitive gamification seem promising. The effects of this approach have never... Participants were 5.-9. semester medical students (n = 48), recruited in an elective evidence-based medicine subject and randomly distributed to two groups (group 1: n = 23; group 2: n = 25). Both acc... Students' improvements in e-test scores after training with the corresponding topics in the learning application can be attributed to chance. Even though the majority enjoyed playing and felt motivate... The authors found no evidence for benefits of the investigated learning programme on students' risk competence or on their internal motivation. The majority disapproved the competitive concept, indica...

Face masks while exercising trial (MERIT): a cross-over randomised controlled study.

Physical exertion is a high-risk activity for aerosol emission of respiratory pathogens. We aimed to determine the safety and tolerability of healthy young adults wearing different types of face mask ... Cross-over randomised controlled study, completed between June 2021 and January 2022.... Volunteers aged 18-35 years, who exercised regularly and had no significant pre-existing health conditions.... Comparison of wearing a surgical, cloth and filtering face piece (FFP3) mask to no mask during 4×15 min bouts of exercise. Exercise was running outdoors or indoor rowing at moderate-to-high intensity,... The primary outcome was change in oxygen saturations. Secondary outcomes were change in heart rate, perceived impact of face mask wearing during exercise and willingness to wear a face mask for future... All 72 volunteers (mean age 23.9) completed the study. Changes in oxygen saturations did not exceed the prespecified non-inferiority margin (2% difference) with any mask type compared with no mask. At... This study adds to previous findings (mostly from non-randomised studies) that exercising at moderate-to-high intensity wearing a face mask appears to be safe in healthy, young adults.... NCT04932226....

The effect of pre-match sexual intercourse on football players' performance: a prospective cross over study.

Current research suggests that pre-competition sexual intercourse does not influence athletes' performance. Yet, high quality studies in this field are scarce.... We aimed to investigate whether sexual activity negatively influences physiological performance. We conducted a prospective cross over study, which enrolled active players from the first team of a foo... We enrolled 14 participants who participated in 88 football matches. The mean age was 29.7 (±3.8) years and the majority were in permanent relationships for longer than 6 months (78.6%). We identified... To the best of our knowledge, this study is the first to show that sexual intercourse the night before a football match may have a negative influence on players' performance....

Characterising applied forces during positive pressure ventilation: a randomised cross-over simulation study.

To characterise applied force on the face and head during simulated mask ventilation with varying mask, device and expertise level.... Randomised cross-over simulation study.... A quiet, empty room in the children's hospital.... Neonatal healthcare providers, categorised as novices and experts in positive pressure ventilation (PPV).... PPV for 2 min each in a 2×2 within-subjects design with two masks (round and anatomic) and two ventilation devices (T-piece and self-inflating bag (SIB)).... Applied force (Newton (N)) measured under the head and at four locations on the manikin's face (nasal bridge, mentum, left and right zygomatic arches) and symmetry of force applied around the mask rim... For the 51 participants, force applied to the head was greater with the SIB than the T-piece (mean (SD): 16.03 (6.96) N vs 14.31 (5.16) N) and greater with the anatomic mask than the round mask (mean ... We characterised an initial dataset of applied forces on the face and head during simulated PPV and described differences in force when considering mask type, device type and expertise....

Pediatric olfactory home testing using regular household items: A cross-over validation study.

To develop an olfactory test that can be conducted by an untrained person using common household items and to introduce a German version of the Chemosensory Pleasure Scale for Children (CPS-C(de)).... This olfactory home test was developed in phases including evaluation of odors for suitability in a home setting. Parents of 50 children (ages 6-17) were then equipped with instruction manuals and par... Fourteen items were tested for feasibility, and all were identified on a sufficient rate (≥66%, mean ± SD of 93.3% ± 9.5%). Bland Altman Plot analysis between home testing and the U-Sniff test was nea... Remote olfactory testing in children using household items is feasible. The CPS-C(de) may be of value for future olfactory studies....