questionsmedicales.fr
Facteurs biologiques
Toxines biologiques
Toxines bactériennes
Endotoxines
Endotoxines : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Tests de laboratoire
Endotoxines
Culture bactérienne
Endotoxines
Symptômes
5
Système immunitaire
Choc septique
Choc septique
Hypotension
Prévention
5
Sécurité en laboratoire
Équipements de protection
Infections nosocomiales
Hygiène hospitalière
Traitements
5
Antibiotiques
Soins de soutien
Corticostéroïdes
Inflammation
Choc septique
Vasopresseurs
Antidotes
Traitement symptomatique
Prise en charge précoce
Complications
Complications
5
Choc septique
Insuffisance organique
Défaillance organique
Inflammation
Syndrome de détresse respiratoire
Inflammation pulmonaire
Dommages neurologiques
Inflammation systémique
Facteurs de risque
5
Facteurs de risque
Immunodépression
Infections bactériennes
Gram-négatif
Interventions chirurgicales
Infections
Diabète
Système immunitaire
Conditions de vie
Bactéries
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"text": "Le diagnostic repose sur des tests sanguins, cultures et évaluation clinique."
}
},
{
"@type": "Question",
"name": "Quels tests sont utilisés pour détecter les endotoxines ?",
"position": 2,
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"@type": "Question",
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"position": 3,
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"@type": "Question",
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"@type": "Question",
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"position": 6,
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"@type": "Question",
"name": "Comment les endotoxines affectent-elles le système immunitaire ?",
"position": 7,
"acceptedAnswer": {
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"text": "Elles provoquent une réponse inflammatoire excessive, pouvant mener à un choc."
}
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{
"@type": "Question",
"name": "Les endotoxines causent-elles des douleurs ?",
"position": 8,
"acceptedAnswer": {
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"text": "Oui, elles peuvent provoquer des douleurs abdominales et musculaires."
}
},
{
"@type": "Question",
"name": "Quels signes indiquent un choc septique dû aux endotoxines ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Hypotension, tachycardie, confusion et peau froide sont des signes clés."
}
},
{
"@type": "Question",
"name": "Les symptômes varient-ils selon l'exposition ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'intensité des symptômes dépend de la dose et de la durée d'exposition."
}
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{
"@type": "Question",
"name": "Comment prévenir l'exposition aux endotoxines ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Éviter les environnements contaminés et respecter les protocoles d'hygiène."
}
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{
"@type": "Question",
"name": "Les vaccins peuvent-ils prévenir les infections à endotoxines ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il n'existe pas de vaccin spécifique contre les endotoxines, mais contre certaines bactéries."
}
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{
"@type": "Question",
"name": "Quelles mesures de sécurité en laboratoire sont nécessaires ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Utiliser des équipements de protection individuelle et des procédures de désinfection."
}
},
{
"@type": "Question",
"name": "Les antibiotiques préventifs sont-ils efficaces ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils peuvent être utilisés dans certains cas à risque, mais pas systématiquement."
}
},
{
"@type": "Question",
"name": "Comment réduire le risque d'infections nosocomiales ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Améliorer l'hygiène hospitalière et le contrôle des infections est essentiel."
}
},
{
"@type": "Question",
"name": "Quel est le traitement principal pour une intoxication par endotoxines ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le traitement inclut des antibiotiques et des soins de soutien pour stabiliser le patient."
}
},
{
"@type": "Question",
"name": "Les corticostéroïdes sont-ils efficaces contre les endotoxines ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils peuvent réduire l'inflammation, mais leur utilisation est controversée."
}
},
{
"@type": "Question",
"name": "Comment traiter le choc septique causé par des endotoxines ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le traitement nécessite des fluides intraveineux et des vasopresseurs."
}
},
{
"@type": "Question",
"name": "Les antidotes existent-ils pour les endotoxines ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il n'existe pas d'antidote spécifique, le traitement est symptomatique."
}
},
{
"@type": "Question",
"name": "Quelle est l'importance de la prise en charge précoce ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une prise en charge rapide améliore les chances de survie et réduit les complications."
}
},
{
"@type": "Question",
"name": "Quelles sont les complications possibles d'une intoxication par endotoxines ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent le choc septique, l'insuffisance organique et la mort."
}
},
{
"@type": "Question",
"name": "Comment les endotoxines affectent-elles les organes ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles peuvent provoquer une défaillance multi-organique en raison de l'inflammation."
}
},
{
"@type": "Question",
"name": "Le syndrome de détresse respiratoire est-il lié aux endotoxines ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'inflammation pulmonaire peut entraîner un syndrome de détresse respiratoire."
}
},
{
"@type": "Question",
"name": "Les endotoxines peuvent-elles causer des dommages neurologiques ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles peuvent provoquer des troubles neurologiques en raison de l'inflammation systémique."
}
},
{
"@type": "Question",
"name": "Quel est le pronostic après une exposition aux endotoxines ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le pronostic dépend de la rapidité du traitement et de la gravité de l'exposition."
}
},
{
"@type": "Question",
"name": "Quels sont les principaux facteurs de risque d'intoxication par endotoxines ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les patients immunodéprimés, les personnes âgées et les hospitalisés sont à risque."
}
},
{
"@type": "Question",
"name": "Les infections bactériennes augmentent-elles le risque d'endotoxines ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les infections par des bactéries Gram-négatives sont un facteur de risque majeur."
}
},
{
"@type": "Question",
"name": "Les interventions chirurgicales augmentent-elles le risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les interventions chirurgicales peuvent exposer à des endotoxines, surtout en cas d'infection."
}
},
{
"@type": "Question",
"name": "Le diabète est-il un facteur de risque pour les endotoxines ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le diabète peut affaiblir le système immunitaire et augmenter le risque d'infections."
}
},
{
"@type": "Question",
"name": "Les conditions de vie insalubres augmentent-elles le risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elles favorisent la prolifération bactérienne et l'exposition aux endotoxines."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 06/02/2025
Contenu vérifié selon les dernières recommandations médicales
3 publications dans cette catégorie
Affiliations :
Microcoat Biotechnologie GmbH, Am Neuland 3, 82347 Bernried am Stanberger See, Germany. j.reich@microcoat.de.
Publications dans "Endotoxines" :
3 publications dans cette catégorie
Affiliations :
Department of Biochemistry, University of Cambridge, Cambridge, CB2 1QW, UK. gcb3@cam.ac.uk.
Publications dans "Endotoxines" :
3 publications dans cette catégorie
Affiliations :
Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Spectral Medical Inc., Toronto, Ontario, Canada.
Publications dans "Endotoxines" :
2 publications dans cette catégorie
Affiliations :
Nanomedicine and Molecular Imaging Group, Department of Clinical Medicine, Trinity Translational Medicine Institute, Dublin, Ireland.
Laboratory of Biological Characterization of Advanced Materials (LBCAM), Trinity Translational Medicine Institute, Trinity College Dublin, Dublin, Ireland.
Publications dans "Endotoxines" :
2 publications dans cette catégorie
Affiliations :
Nanomedicine and Molecular Imaging Group, Department of Clinical Medicine, Trinity Translational Medicine Institute, Dublin, Ireland.
Laboratory of Biological Characterization of Advanced Materials (LBCAM), Trinity Translational Medicine Institute, Trinity College Dublin, Dublin, Ireland.
Advanced Materials and Bioengineering Research (AMBER) Centre, CRANN institute, Trinity College Dublin, Dublin, Ireland.
Publications dans "Endotoxines" :
2 publications dans cette catégorie
Affiliations :
Laboratory of Biophotonics and Advanced Microscopy, Institute of Biochemistry and Cell Biology (IBBC), National Research Council (CNR), Napoli, Italy.
Publications dans "Endotoxines" :
2 publications dans cette catégorie
Affiliations :
Laboratory of Biophotonics and Advanced Microscopy, Institute of Biochemistry and Cell Biology (IBBC), National Research Council (CNR), Napoli, Italy.
Publications dans "Endotoxines" :
2 publications dans cette catégorie
Affiliations :
Laboratory of Innate Immunity, Inflammation and Immuno-nanosafety, IBBC-CNR, Napoli, Italy.
Publications dans "Endotoxines" :
2 publications dans cette catégorie
Affiliations :
Laboratory of Innate Immunity, Inflammation and Immuno-nanosafety, IBBC-CNR, Napoli, Italy.
Publications dans "Endotoxines" :
2 publications dans cette catégorie
Affiliations :
Laboratory of Biophotonics and Advanced Microscopy, Institute of Biochemistry and Cell Biology (IBBC), National Research Council (CNR), Napoli, Italy.
Publications dans "Endotoxines" :
2 publications dans cette catégorie
Affiliations :
Toray Medical Co., Ltd., Tokyo, Japan.
Publications dans "Endotoxines" :
2 publications dans cette catégorie
Affiliations :
Microbial Solutions, Charles River Laboratories, 1023 Wappoo Road, Suite 43-B, Charleston, SC 29407, United States.
Publications dans "Endotoxines" :
2 publications dans cette catégorie
Affiliations :
Department of Chemical and Biochemical Engineering, Missouri University of Science and Technology, Rolla, Missouri.
Publications dans "Endotoxines" :
2 publications dans cette catégorie
Affiliations :
Department of Chemical and Biochemical Engineering, Missouri University of Science and Technology, Rolla, Missouri.
Publications dans "Endotoxines" :
2 publications dans cette catégorie
Affiliations :
Department of Occupational and Environmental Health, University of Iowa, Iowa City, IA, United States.
Publications dans "Endotoxines" :
2 publications dans cette catégorie
Affiliations :
Department of Occupational and Environmental Health, University of Iowa, Iowa City, IA, United States.
Publications dans "Endotoxines" :
1 publication dans cette catégorie
Affiliations :
Microcoat Biotechnologie GmbH, Am Neuland 3, 82347 Bernried am Stanberger See, Germany. f.weyer@microcoat.de.
Publications dans "Endotoxines" :
1 publication dans cette catégorie
Affiliations :
LPS (Laboratory Program Support) Consulting Office, Tokyo 160-0023, Japan. htamura@lpsct.com.
Department of Host Defense and Biochemical Research, Juntendo University Graduate School of Medicine, Tokyo 113-8431, Japan. htamura@lpsct.com.
Publications dans "Endotoxines" :
1 publication dans cette catégorie
Affiliations :
Department of Host Defense and Biochemical Research, Juntendo University Graduate School of Medicine, Tokyo 113-8431, Japan. nagaokai@juntendo.ac.jp.
Publications dans "Endotoxines" :
1 publication dans cette catégorie
Affiliations :
Institute of Physical and Theoretical Chemistry, University of Regensburg, 93040 Regensburg, Germany. Hubert.Motschmann@chemie.uni-regensburg.de.
Publications dans "Endotoxines" :
To investigate the clinical characteristics and associated factors of colonic polyps in patients with acromegaly....
Clinical characteristics and colonoscopy findings of 86 acromegaly patients who received treatment were retrospectively reviewed, and colonoscopy findings and the correlation with growth hormone (GH)-...
The prevalence of colonic polyps in acromegaly patients was 40.7% and increased significantly with advanced age, especially in those ≥50 years. Multiple polyps (62.8%) and colonic polyps in the left c...
The acromegalic patients are a population with a high prevalence of colonic polyps. GHPA volumes and IGF-1×ULN levels may be predictors of colonic polyp occurrence....
Combined endoscopic robotic surgery is a surgical technique that modifies traditional endoscopic laparoscopic surgery with robotic assistance to aid in the removal of complex colonic polyps. This tech...
This study aimed to evaluate the safety and outcomes of combined endoscopic robotic surgery....
A retrospective review of a prospective database....
East Jefferson General Hospital, Metairie, Louisiana....
Ninety-three consecutive patients who underwent combined endoscopic robotic surgery from March 2018 to October 2021 were included in the study....
Operative time, intraoperative complication, 30-day postoperative complication, hospital length of stay, and follow-up pathology report results were the main outcome measures....
Combined endoscopic robotic surgery was completed in 88 of 93 participants (95%). Among the 88 participants who completed combined endoscopic robotic surgery, the average age was 66 years (SD = 10), B...
Limitations for our study include a lack of randomization and follow-up rate to assess for recurrence. The low compliance rate may be due to procedure cancelations/difficulty scheduling because of cha...
Compared to literature-reported statistics for its laparoscopic counterpart, combined endoscopic robotic surgery was associated with decreased operation times and resection site polyp recurrence. See ...
ANTECEDENTES:La cirugía robótica endoscópica combinada es una técnica quirúrgica que modifica la cirugía laparoscópica endoscópica tradicional con asistencia robótica para ayudar en la extracción de p...
Sporadic colorectal cancer arises from an adenoma. As mutations in the adenomatous polyposis coli (APC) tumor suppressor gene have been frequently detected in colorectal adenomas, the APC gene is cons...
A significant problem encountered in the resection of large, complex colonic polyps is delayed bleeding. This can occur up to two weeks after the procedure and is a significant source of comorbidity. ...
To analyze our experience with adenoma detection rates in patients with liver cirrhosis in a community setting....
Colorectal cancer (CRC) is the third most common cancer and leading cause of cancer death in men and women in the USA. The majority of CRCs arise from premalignant polyps (adenomas), which are typical...
A total of 351 colonoscopies were performed (2006 to 2019) in patients with liver cirrhosis. Mean age was 62.3 ± 9.4 years, there were 158 females and 193 males. Adenomas were found in 159 procedures ...
Adenoma detection rates in patients with cirrhosis (49%) undergoing elective colonoscopy were higher than rates reported in the literature for LT candidates (22-42%) undergoing standardized screenings...
The fragmentation of polyps affects complete resection confirmation. The primary aim of this study was to assess the feasibility of a novel polyp retrieval bag for reducing the fragmentation rate of c...
Patients with a 5-15 mm colon polyp were recruited and randomized into two groups at a 1:1 ratio. After polyp resection, polyps obtained from patients in the treatment group were extracted via a novel...
From January to July 2022, 225 patients were assessed for eligibility. The study participants included 204 patients, and seven patients whose samples were not retrieved were excluded. Polyp fragmentat...
This study demonstrated that the polyp retrieval bag was safe and feasible for reducing the fragmentation rate of retrieved polyps....
The study was registered at ClinicalTrials.gov (NCT05189912, 1/12/2021)....
Colorectal cancer is the second most deadly and third most common cancer in the world. Its development is heterogenous, with multiple mechanisms of carcinogenesis. Two distinct mechanisms include the ...
Large (≥20 mm) nonpedunculated colorectal polyps (LNPCPs) may have synchronous LNPCPs in up to 18% of cases. The nature of this relationship has not been investigated. We aimed to examine the relation...
Consecutive patients referred for resection of LNPCPs over 130 months until March 2022 were enrolled. Serrated lesions and mixed granularity LNPCPs were excluded from analysis. Patients with multiple ...
There were 3149 of 3381 patients (93.1%) who had a single LNPCP. In 232 (6.9%) a synchronous lesion was detected. Solitary lesions had a median size of 35 mm with a predominant Paris 0-IIa morphology ...
We found that 6.9% of LNPCPs have synchronous disease, with NG-LNPCPs demonstrating a greater than 4-fold increased risk. With post-colonoscopy interval cancers exceeding 5%, endoscopists must be cogn...
gov, NCT01368289; NCT02000141; NCT02198729....
Pedunculated polyps (PPs) in the colon are usually resected with hot snare polypectomy to prevent immediate postpolypectomy bleeding (IPPB). This study aimed to evaluate the safety of CSP of <10 mm PP...
Patients undergoing colonoscopy from February 18, 2019, to April 24, 2020, and were found to have at least 1 ≤10 mm PP resected with CSP were included prospectively in a continuous quality improvement...
We found 239 eligible polyps in 182 patients. The mean (SD) age was 58.8 (8.3) years, and 61% were males. IPPB occurred in 72 of 239 polyps, corresponding to a per-polyp bleeding percentage of 30.1% a...
CSP can be used for resection of ≤10 mm PPs. It is associated with a lower risk of immediate bleeding than the common perception among gastroenterologists....
Polyp detection through colonoscopy is a widely used method to prevent colorectal cancer. The automation of this process aided by artificial intelligence allows faster and improved detection of polyps...