questionsmedicales.fr
Facteurs biologiques
Toxines biologiques
Toxines bactériennes
Endotoxines
Endotoxines : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Tests de laboratoire
Endotoxines
Culture bactérienne
Endotoxines
Symptômes
5
Système immunitaire
Choc septique
Choc septique
Hypotension
Prévention
5
Sécurité en laboratoire
Équipements de protection
Infections nosocomiales
Hygiène hospitalière
Traitements
5
Antibiotiques
Soins de soutien
Corticostéroïdes
Inflammation
Choc septique
Vasopresseurs
Antidotes
Traitement symptomatique
Prise en charge précoce
Complications
Complications
5
Choc septique
Insuffisance organique
Défaillance organique
Inflammation
Syndrome de détresse respiratoire
Inflammation pulmonaire
Dommages neurologiques
Inflammation systémique
Facteurs de risque
5
Facteurs de risque
Immunodépression
Infections bactériennes
Gram-négatif
Interventions chirurgicales
Infections
Diabète
Système immunitaire
Conditions de vie
Bactéries
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"text": "Le diagnostic repose sur des tests sanguins, cultures et évaluation clinique."
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{
"@type": "Question",
"name": "Quels tests sont utilisés pour détecter les endotoxines ?",
"position": 2,
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"@type": "Question",
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"position": 5,
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"@type": "Question",
"name": "Quels sont les symptômes d'une intoxication par endotoxines ?",
"position": 6,
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"@type": "Question",
"name": "Comment les endotoxines affectent-elles le système immunitaire ?",
"position": 7,
"acceptedAnswer": {
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}
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{
"@type": "Question",
"name": "Les endotoxines causent-elles des douleurs ?",
"position": 8,
"acceptedAnswer": {
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"text": "Oui, elles peuvent provoquer des douleurs abdominales et musculaires."
}
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{
"@type": "Question",
"name": "Quels signes indiquent un choc septique dû aux endotoxines ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Hypotension, tachycardie, confusion et peau froide sont des signes clés."
}
},
{
"@type": "Question",
"name": "Les symptômes varient-ils selon l'exposition ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'intensité des symptômes dépend de la dose et de la durée d'exposition."
}
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{
"@type": "Question",
"name": "Comment prévenir l'exposition aux endotoxines ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Éviter les environnements contaminés et respecter les protocoles d'hygiène."
}
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{
"@type": "Question",
"name": "Les vaccins peuvent-ils prévenir les infections à endotoxines ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il n'existe pas de vaccin spécifique contre les endotoxines, mais contre certaines bactéries."
}
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{
"@type": "Question",
"name": "Quelles mesures de sécurité en laboratoire sont nécessaires ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Utiliser des équipements de protection individuelle et des procédures de désinfection."
}
},
{
"@type": "Question",
"name": "Les antibiotiques préventifs sont-ils efficaces ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils peuvent être utilisés dans certains cas à risque, mais pas systématiquement."
}
},
{
"@type": "Question",
"name": "Comment réduire le risque d'infections nosocomiales ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Améliorer l'hygiène hospitalière et le contrôle des infections est essentiel."
}
},
{
"@type": "Question",
"name": "Quel est le traitement principal pour une intoxication par endotoxines ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le traitement inclut des antibiotiques et des soins de soutien pour stabiliser le patient."
}
},
{
"@type": "Question",
"name": "Les corticostéroïdes sont-ils efficaces contre les endotoxines ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils peuvent réduire l'inflammation, mais leur utilisation est controversée."
}
},
{
"@type": "Question",
"name": "Comment traiter le choc septique causé par des endotoxines ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le traitement nécessite des fluides intraveineux et des vasopresseurs."
}
},
{
"@type": "Question",
"name": "Les antidotes existent-ils pour les endotoxines ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il n'existe pas d'antidote spécifique, le traitement est symptomatique."
}
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{
"@type": "Question",
"name": "Quelle est l'importance de la prise en charge précoce ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une prise en charge rapide améliore les chances de survie et réduit les complications."
}
},
{
"@type": "Question",
"name": "Quelles sont les complications possibles d'une intoxication par endotoxines ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent le choc septique, l'insuffisance organique et la mort."
}
},
{
"@type": "Question",
"name": "Comment les endotoxines affectent-elles les organes ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles peuvent provoquer une défaillance multi-organique en raison de l'inflammation."
}
},
{
"@type": "Question",
"name": "Le syndrome de détresse respiratoire est-il lié aux endotoxines ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'inflammation pulmonaire peut entraîner un syndrome de détresse respiratoire."
}
},
{
"@type": "Question",
"name": "Les endotoxines peuvent-elles causer des dommages neurologiques ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles peuvent provoquer des troubles neurologiques en raison de l'inflammation systémique."
}
},
{
"@type": "Question",
"name": "Quel est le pronostic après une exposition aux endotoxines ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le pronostic dépend de la rapidité du traitement et de la gravité de l'exposition."
}
},
{
"@type": "Question",
"name": "Quels sont les principaux facteurs de risque d'intoxication par endotoxines ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les patients immunodéprimés, les personnes âgées et les hospitalisés sont à risque."
}
},
{
"@type": "Question",
"name": "Les infections bactériennes augmentent-elles le risque d'endotoxines ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les infections par des bactéries Gram-négatives sont un facteur de risque majeur."
}
},
{
"@type": "Question",
"name": "Les interventions chirurgicales augmentent-elles le risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les interventions chirurgicales peuvent exposer à des endotoxines, surtout en cas d'infection."
}
},
{
"@type": "Question",
"name": "Le diabète est-il un facteur de risque pour les endotoxines ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le diabète peut affaiblir le système immunitaire et augmenter le risque d'infections."
}
},
{
"@type": "Question",
"name": "Les conditions de vie insalubres augmentent-elles le risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elles favorisent la prolifération bactérienne et l'exposition aux endotoxines."
}
}
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}
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}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 06/02/2025
Contenu vérifié selon les dernières recommandations médicales
3 publications dans cette catégorie
Affiliations :
Microcoat Biotechnologie GmbH, Am Neuland 3, 82347 Bernried am Stanberger See, Germany. j.reich@microcoat.de.
Publications dans "Endotoxines" :
3 publications dans cette catégorie
Affiliations :
Department of Biochemistry, University of Cambridge, Cambridge, CB2 1QW, UK. gcb3@cam.ac.uk.
Publications dans "Endotoxines" :
3 publications dans cette catégorie
Affiliations :
Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Spectral Medical Inc., Toronto, Ontario, Canada.
Publications dans "Endotoxines" :
2 publications dans cette catégorie
Affiliations :
Nanomedicine and Molecular Imaging Group, Department of Clinical Medicine, Trinity Translational Medicine Institute, Dublin, Ireland.
Laboratory of Biological Characterization of Advanced Materials (LBCAM), Trinity Translational Medicine Institute, Trinity College Dublin, Dublin, Ireland.
Publications dans "Endotoxines" :
2 publications dans cette catégorie
Affiliations :
Nanomedicine and Molecular Imaging Group, Department of Clinical Medicine, Trinity Translational Medicine Institute, Dublin, Ireland.
Laboratory of Biological Characterization of Advanced Materials (LBCAM), Trinity Translational Medicine Institute, Trinity College Dublin, Dublin, Ireland.
Advanced Materials and Bioengineering Research (AMBER) Centre, CRANN institute, Trinity College Dublin, Dublin, Ireland.
Publications dans "Endotoxines" :
2 publications dans cette catégorie
Affiliations :
Laboratory of Biophotonics and Advanced Microscopy, Institute of Biochemistry and Cell Biology (IBBC), National Research Council (CNR), Napoli, Italy.
Publications dans "Endotoxines" :
2 publications dans cette catégorie
Affiliations :
Laboratory of Biophotonics and Advanced Microscopy, Institute of Biochemistry and Cell Biology (IBBC), National Research Council (CNR), Napoli, Italy.
Publications dans "Endotoxines" :
2 publications dans cette catégorie
Affiliations :
Laboratory of Innate Immunity, Inflammation and Immuno-nanosafety, IBBC-CNR, Napoli, Italy.
Publications dans "Endotoxines" :
2 publications dans cette catégorie
Affiliations :
Laboratory of Innate Immunity, Inflammation and Immuno-nanosafety, IBBC-CNR, Napoli, Italy.
Publications dans "Endotoxines" :
2 publications dans cette catégorie
Affiliations :
Laboratory of Biophotonics and Advanced Microscopy, Institute of Biochemistry and Cell Biology (IBBC), National Research Council (CNR), Napoli, Italy.
Publications dans "Endotoxines" :
2 publications dans cette catégorie
Affiliations :
Toray Medical Co., Ltd., Tokyo, Japan.
Publications dans "Endotoxines" :
2 publications dans cette catégorie
Affiliations :
Microbial Solutions, Charles River Laboratories, 1023 Wappoo Road, Suite 43-B, Charleston, SC 29407, United States.
Publications dans "Endotoxines" :
2 publications dans cette catégorie
Affiliations :
Department of Chemical and Biochemical Engineering, Missouri University of Science and Technology, Rolla, Missouri.
Publications dans "Endotoxines" :
2 publications dans cette catégorie
Affiliations :
Department of Chemical and Biochemical Engineering, Missouri University of Science and Technology, Rolla, Missouri.
Publications dans "Endotoxines" :
2 publications dans cette catégorie
Affiliations :
Department of Occupational and Environmental Health, University of Iowa, Iowa City, IA, United States.
Publications dans "Endotoxines" :
2 publications dans cette catégorie
Affiliations :
Department of Occupational and Environmental Health, University of Iowa, Iowa City, IA, United States.
Publications dans "Endotoxines" :
1 publication dans cette catégorie
Affiliations :
Microcoat Biotechnologie GmbH, Am Neuland 3, 82347 Bernried am Stanberger See, Germany. f.weyer@microcoat.de.
Publications dans "Endotoxines" :
1 publication dans cette catégorie
Affiliations :
LPS (Laboratory Program Support) Consulting Office, Tokyo 160-0023, Japan. htamura@lpsct.com.
Department of Host Defense and Biochemical Research, Juntendo University Graduate School of Medicine, Tokyo 113-8431, Japan. htamura@lpsct.com.
Publications dans "Endotoxines" :
1 publication dans cette catégorie
Affiliations :
Department of Host Defense and Biochemical Research, Juntendo University Graduate School of Medicine, Tokyo 113-8431, Japan. nagaokai@juntendo.ac.jp.
Publications dans "Endotoxines" :
1 publication dans cette catégorie
Affiliations :
Institute of Physical and Theoretical Chemistry, University of Regensburg, 93040 Regensburg, Germany. Hubert.Motschmann@chemie.uni-regensburg.de.
Publications dans "Endotoxines" :
Contrast sensitivity measurements using a computer display have been reported to lack accuracy when displaying small contrasts. This report investigates if the characterization/calibration of display ...
This study aimed to investigate what errors in contrast sensitivity may result from characterizing a display by fitting a gamma curve through physical or psychophysical luminance measurement data....
The luminance functions of four different in-plane switching liquid crystal displays (IPS LCDs) have been measured for all 256 gray levels (the actual luminance function). This has been compared with ...
The amount of error differs considerably between the displays. In general, for large contrasts (Michelson log CS <1.2), the error is acceptable (<<0.15 log unit). However, for smaller contrasts (Miche...
To improve the accuracy of testing contrast sensitivity with an LCD, it is necessary to fully characterize the display, measuring the luminance of each gray level instead of fitting a smooth gamma fun...
The contrast sensitivity function (CSF) is a fundamental signature of the visual system that has been measured extensively in several species. It is defined by the visibility threshold for sinusoidal ...
The purpose of this study was to determine intrasession repeatability of a worksheet style contrast sensitivity test (SpotChecks) in children and agreement with an established contrast sensitivity tes...
Forty-three children aged 4 to 12 years participated in this single visit study that included two administrations of the SpotChecks binocularly, a single administration of the Pelli-Robson test and ot...
The mean difference in log contrast sensitivity (logCS) between two administrations of the SpotChecks was 0.01, with a coefficient of repeatability (1.96*SD of differences) of 0.14 logCS. The mean dif...
The SpotChecks test shows good intrasession repeatability and excellent agreement with the Pelli-Robson test in children. Contrast sensitivity showed an increase in logCS with age in children for both...
We developed and validated digital twins (DTs) for contrast sensitivity function (CSF) across 12 prediction tasks using a data-driven, generative model approach based on a hierarchical Bayesian model ...
There are limited tests of contrast sensitivity (CS) for use in children. The Hiding Heidi (HH) is suitable for all cognitive abilities, but has a ceiling effect. The Double Happy (DH) test has compar...
Tests were repeated under different conditions to reduce the contrast. Room illumination was 20,900{plus minus}2% lux in bright conditions and 2,000{plus minus}2% lux in dim conditions, both condition...
50 participants, age 18-62 years (mean{plus minus}standard deviation: 24.5{plus minus}7.98), were assessed. On HH 94% (...
The DH test has better agreement with PR than HH and is better at detecting CS changes, highlighting the advantages of use in clinical practice....
Potential cognitive and physiological alterations due to space environments have been investigated in long-term space flight and various microgravity-like conditions, for example, head-down tilt (HDT)...
The binocular alignment of the eyes involves both voluntary and reflexive mechanisms, but little is known about the visual input and neurological pathway of the reflex component. Our studies examined ...
Contrast processing is a fundamental function of the visual system, and contrast sensitivity as a function of spatial frequency (CSF) provides critical information about the integrity of the system. H...
To determine the ability of the Internet-based Spaeth/Richman Contrast Sensitivity (SPARCS) in assessing the change in contrast sensitivity (both central and peripheral) post-treatment with travoprost...
This is a prospective observational study....
Data of 62 eyes (33 patients) undergoing treatment for naïve POAG patients were analysed. Patients were followed up for a period of six months after starting topical travoprost (Travatan 0.004%, Alcon...
Mean total SPARCS score at baseline was 69 ± 10.99, improved to 74.62 ± 9.50 after 6 months of therapy (p: 0.001) in all the glaucoma severity groups. Mean SPARCS score at baseline in mild glaucoma gr...
Both central and peripheral CS improve following IOP reduction with travoprost. Change in the CS has a significant correlation with RNFL thickness and the perimetric indices....
In this study, effects of smoking on colour vision with the Farnsworth−Munsell 100 Hue test (FM100h) and achromatic (A), red-green (RG), and blue-yellow (BY) contrast sensitivity functions were evalua...