questionsmedicales.fr
Phénomènes génétiques
Structures génétiques
Génome
Composants de génome
Gènes
Gènes régulateurs
Gènes switch
Gènes switch : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Analyse génétique
Expression génique
Marqueurs épigénétiques
Méthylation
Symptômes
5
Symptômes
Troubles métaboliques
Développement embryonnaire
Développement cellulaire
Anomalies congénitales
Cancers
Comportement
Traits cognitifs
Troubles neurologiques
Dysrégulation
Prévention
5
Dépistage génétique
Interventions précoces
Mode de vie sain
Alimentation équilibrée
Conseils génétiques
Évaluation des risques
Suivi médical
Détection précoce
Traitements
5
Thérapie génique
Médicaments ciblés
Médecine personnalisée
Profil génétique
Essais cliniques
Thérapies
Efficacité des traitements
Pathologie
Effets secondaires
Réactions immunitaires
Complications
5
Cancers
Troubles métaboliques
Maladies héréditaires
Génétique
Transmission familiale
Génétique
Complications
Gestion des maladies
Longévité
Espérance de vie
Facteurs de risque
5
Facteurs environnementaux
Génétique
Variations génétiques
Prédisposition
Infections
Expression génique
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"@type": "Question",
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"name": "Les gènes switch influencent-ils le comportement ?",
"position": 9,
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"acceptedAnswer": {
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}
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"@type": "Question",
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"@type": "Question",
"name": "Quels modes de vie peuvent aider à prévenir ces maladies ?",
"position": 12,
"acceptedAnswer": {
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"text": "Un mode de vie sain, incluant une alimentation équilibrée et de l'exercice, est bénéfique."
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"@type": "Question",
"name": "Les conseils génétiques sont-ils utiles ?",
"position": 13,
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"@type": "Question",
"name": "Y a-t-il des vaccins pour prévenir les effets des gènes switch ?",
"position": 14,
"acceptedAnswer": {
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"text": "Actuellement, il n'existe pas de vaccins spécifiques pour les gènes switch."
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{
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"name": "Comment traiter les dysfonctionnements des gènes switch ?",
"position": 16,
"acceptedAnswer": {
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"text": "Des thérapies géniques et des médicaments ciblés peuvent être utilisés."
}
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"position": 17,
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}
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"name": "Y a-t-il des essais cliniques pour ces traitements ?",
"position": 18,
"acceptedAnswer": {
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}
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{
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"name": "Les traitements sont-ils efficaces ?",
"position": 19,
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{
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"position": 20,
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"position": 21,
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"@type": "Question",
"name": "Les gènes switch peuvent-ils causer des maladies héréditaires ?",
"position": 22,
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}
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{
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"name": "Y a-t-il des risques de transmission familiale ?",
"position": 23,
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}
},
{
"@type": "Question",
"name": "Les complications sont-elles réversibles ?",
"position": 24,
"acceptedAnswer": {
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"text": "Certaines complications peuvent être gérées, mais d'autres peuvent être irréversibles."
}
},
{
"@type": "Question",
"name": "Comment les gènes switch affectent-ils la longévité ?",
"position": 25,
"acceptedAnswer": {
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"text": "Des dysfonctionnements peuvent réduire l'espérance de vie en augmentant le risque de maladies."
}
},
{
"@type": "Question",
"name": "Quels facteurs de risque sont associés aux gènes switch ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des facteurs environnementaux, génétiques et comportementaux peuvent influencer leur activité."
}
},
{
"@type": "Question",
"name": "L'âge est-il un facteur de risque ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'âge peut affecter l'expression des gènes switch et le risque de maladies."
}
},
{
"@type": "Question",
"name": "Le mode de vie influence-t-il les gènes switch ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des habitudes comme le tabagisme ou l'alimentation peuvent moduler leur activité."
}
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{
"@type": "Question",
"name": "Les facteurs génétiques jouent-ils un rôle ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des variations génétiques peuvent prédisposer à des dysfonctionnements des gènes switch."
}
},
{
"@type": "Question",
"name": "Les infections peuvent-elles affecter les gènes switch ?",
"position": 30,
"acceptedAnswer": {
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"text": "Certaines infections peuvent altérer l'expression des gènes switch et provoquer des maladies."
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Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 14/03/2025
Contenu vérifié selon les dernières recommandations médicales
5 publications dans cette catégorie
Affiliations :
ETH Zürich, Department of Biosystems Science and Engineering, Mattenstrasse 26, 4058, Basel, Switzerland; University of Basel, Faculty of Life Science, Basel, Switzerland. Electronic address: fussenegger@bsse.ethz.ch.
Publications dans "Gènes switch" :
3 publications dans cette catégorie
Affiliations :
ETH Zürich, Department of Biosystems Science and Engineering, Mattenstrasse 26, 4058, Basel, Switzerland.
Publications dans "Gènes switch" :
2 publications dans cette catégorie
Affiliations :
Department of Chemistry, Physics and Applied Mathematics, State University of New York at Stony Brook, Stony Brook, New York 11794, USA.
Publications dans "Gènes switch" :
2 publications dans cette catégorie
Affiliations :
Department of Chemistry, University of Konstanz, Universitätsstraße 10, 78457 Konstanz, Germany; Konstanz Research School Chemical Biology (KoRS-CB), University of Konstanz, Universitätsstraße 10, 78457 Konstanz, Germany. Electronic address: joerg.hartig@uni-konstanz.de.
Publications dans "Gènes switch" :
2 publications dans cette catégorie
Publications dans "Gènes switch" :
2 publications dans cette catégorie
Affiliations :
Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden. daniel.bojar@gu.se.
Department of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg, Sweden. daniel.bojar@gu.se.
Publications dans "Gènes switch" :
2 publications dans cette catégorie
Affiliations :
Departamento de Genética, Facultad de Biología, Universidad de Sevilla, Apartado 1095, 41080, Sevilla, Spain.
Publications dans "Gènes switch" :
2 publications dans cette catégorie
Affiliations :
Department of Medical Biochemistry and Microbiology, Uppsala University, 751 23, Uppsala, Sweden.
Publications dans "Gènes switch" :
2 publications dans cette catégorie
Affiliations :
Departamento de Genética, Facultad de Biología, Universidad de Sevilla, Apartado 1095, 41080, Sevilla, Spain.
Publications dans "Gènes switch" :
2 publications dans cette catégorie
Affiliations :
Departamento de Genética, Facultad de Biología, Universidad de Sevilla, Apartado 1095, 41080, Sevilla, Spain.
Centre for Research in Agricultural Genomics, CSIC-IRTA-UAB-UB, Campus UAB, Bellaterra, 08193, Barcelona, Spain.
Publications dans "Gènes switch" :
2 publications dans cette catégorie
Affiliations :
Department of Medical Biochemistry and Microbiology, Uppsala University, 751 23, Uppsala, Sweden.
Publications dans "Gènes switch" :
2 publications dans cette catégorie
Affiliations :
Departamento de Genética, Facultad de Biología, Universidad de Sevilla, Apartado 1095, 41080, Sevilla, Spain. casadesus@us.es.
Publications dans "Gènes switch" :
2 publications dans cette catégorie
Affiliations :
Arizona State University, Tempe, AZ, 85281, USA. dsun25@asu.edu.
Publications dans "Gènes switch" :
2 publications dans cette catégorie
Affiliations :
Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Dr. Aiguader 88, Barcelona, 08003, Spain.
Publications dans "Gènes switch" :
2 publications dans cette catégorie
Affiliations :
Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Dr. Aiguader 88, Barcelona, 08003, Spain.
Publications dans "Gènes switch" :
2 publications dans cette catégorie
Affiliations :
Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Dr. Aiguader 88, Barcelona, 08003, Spain.
Publications dans "Gènes switch" :
2 publications dans cette catégorie
Affiliations :
Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Dr. Aiguader 88, Barcelona, 08003, Spain.
Publications dans "Gènes switch" :
2 publications dans cette catégorie
Affiliations :
Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Dr. Aiguader 88, Barcelona, 08003, Spain. ben.lehner@crg.eu.
Universitat Pompeu Fabra (UPF), Barcelona, Spain. ben.lehner@crg.eu.
ICREA, Pg. Luis Companys 23, Barcelona, 08010, Spain. ben.lehner@crg.eu.
Publications dans "Gènes switch" :
2 publications dans cette catégorie
Affiliations :
Computational Bioscience Research Center (CBRC), Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division, King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia. xin.gao@kaust.edu.sa.
Publications dans "Gènes switch" :
2 publications dans cette catégorie
Affiliations :
ETH Zurich, Department of Biosystems Science and Engineering, Mattenstrasse 26, CH-4058, Basel, Switzerland.
Publications dans "Gènes switch" :
Research on achievement goals is voluminous but focused primarily on intrapersonal regulation. In the present article, we emphasize the integral role that achievement goals also play in the broader pr...
Seriously ill patients whose prioritized healthcare goals are understood by their clinicians are likely better positioned to receive goal-concordant care....
To examine the proportion of seriously ill patients whose prioritized healthcare goal is accurately perceived by their clinician and identify factors associated with accurate perception....
Secondary analysis of a multicenter cluster-randomized trial of outpatients with serious illness and their clinicians. Approximately two weeks after a clinic visit, patients reported their current pri...
Of 252 patients with a prioritized healthcare goal, 60% had their goal accurately perceived by their clinician, 27% were cared for by clinicians who perceived prioritization of the alternative goal, a...
A majority of seriously ill outpatients are cared for by clinicians who accurately perceive their patients' prioritized healthcare goals. However, a substantial portion are not and may be at higher ri...
Across rehabilitation fields, rehabilitees and professionals meet to set rehabilitation goals. Portrayed as an ordinary, yet foundational practice in rehabilitation, participants often find goal-setti...
Studies of goal setting in later life tend to focus on health-related goal setting, are pre-determined by the researcher (i.e., tick box), and/or are focused on a specific geographical area (i.e., one...
Through a cross-sectional, online survey (N = 1,551), this exploratory study examined the qualitative goal content of older adults. Thematic analysis was used to analyze the qualitative data, and biva...
Over 60% of the participants reported setting goals, and participants from the Australia-NZ and Canada-USA regions were more likely to set goals than the UK-Ireland region. The following six overarchi...
This study supports previous research that demonstrates that older adults can and do set personal goals that are wide ranging. These findings support the need for health professionals to consider diff...
This research challenges the idea that teams from more collectivistic cultures tend to perform better. We propose that in contexts in which there are tradeoffs between group goals (i.e., what is best ...
Adult Spinal Deformity (ASD) is a complex pathologic condition with significant impact on quality of life, including pain, loss of function, and fatigue. Achieving realignment goals is crucial for lon...
To develop an expert-informed (including end users) recovery goal menu for adults recovering from critical illness applicable to the community/home setting....
Stage 1 Item generation: iterative development of domains, sub-domains, and goals in consultation with former intensive care patients, family members and expert clinicians. Stage 2 Content validity as...
Virtual consultation meetings facilitated by the research team at King's College London and Guy's and St Thomas' NHS Foundation Trust....
Content validity as assessed by: the Item-Content Validity Index (I-CVI), Scale Level-Content Validity Index/Universal Agreement (S-CVI/UA) score, the Scale Level-Content Validity Index/Average (S-CVI...
Item generation resulted in a goal menu comprising 4 domains, 22 sub-domains and 95 goals assigned as follows: Self-care: 9 sub-domains with 37 goals, Productivity: 7 sub-domains with 13 goals, Leisur...
An expert informed recovery goal menu for former intensive care patients has been developed with excellent content validity. The final goal menu comprises 169 goals within 24 sub-domains grouped under...
This menu will help patients to set goals and increase our understanding of how individuals recover from critical illness....
Goals provide insight into what is important to an individual. We describe the development and application of a mixed methods approach to elicit goals and perceptions about goals in patients with adva...
Patients receiving first-line treatment for advanced lung cancer participated in semi-structured interviews about their goals. Participants self-generated goals, then selected and ranked their three m...
Participants (N = 75, M...
A majority of participant goals focused on meaningful engagement and living well. Goals were largely viewed as attainable and under participants' control. Cancer clinicians may consider how to support...
Patient-centered care reflecting patient preferences and needs is integral to high-quality care. Individualized care is important for psychosocially complex or high-risk patients with multiple chronic...
We sought to clarify facilitators and barriers perceived by primary care physicians in the Veterans Health Administration to delivering patient-centered care for high-risk or complex patients with mul...
We conducted semi-structured telephone interviews from April to July 2020 among physicians across 20 clinical sites. Findings were analyzed with deductive content analysis based on conceptual models o...
Of 23 physicians interviewed, most were female (n = 14/23, 61%), serving in hospital-affiliated outpatient clinics (n = 14/23, 61%). Participants had a mean of 21 (SD = 11.3) years of experience....
Facilitators included the following: effective physician-patient communication to individualize care, prioritize among multiple needs, and elicit goals to improve patient engagement; access to care, e...
Physicians perceived individual physician-patient interactions were the greatest facilitators or barriers to patient-centered care. Efforts to increase primary care patient-centeredness for complex or...
While previous studies have highlighted the role of episodic future thinking in goal pursuit, the underlying cognitive mechanisms remain unexplored. Episodic future thinking may promote goal pursuit b...