questionsmedicales.fr
Enzymes et coenzymes
Enzymes
Transferases
One-carbon group transferases
Methyltransferases
Protein Methyltransferases
Protein-arginine N-methyltransferases
Protein-arginine N-methyltransferases : Questions médicales fréquentes
Termes MeSH sélectionnés :
Printing, Three-Dimensional
Diagnostic
5
Diagnostic
Tests génétiques
Tests enzymatiques
Activité enzymatique
Symptômes
Troubles neurologiques
Tests génétiques
Mutations
Symptômes
5
Carence
Troubles cognitifs
Troubles de l'humeur
Psychiatrie
Troubles neurologiques
Convulsions
Enfants
Retards de développement
Prévention
5
Prévention
Alimentation équilibrée
Dépistage
Conseils génétiques
Éducation à la santé
Sensibilisation
Suivi médical
État de santé
Traitements
5
Traitements
Suppléments nutritionnels
Médicaments
Régulation enzymatique
Thérapies géniques
Mutations
Nutrition
Fonction enzymatique
Traitements personnalisés
Besoins individuels
Complications
5
Complications
Neurologiques
Troubles cardiovasculaires
Risque
Qualité de vie
Limitations fonctionnelles
Complications chroniques
Santé globale
Prévention
Traitement précoce
Facteurs de risque
5
Facteurs de risque
Antécédents familiaux
Groupes à risque
Troubles métaboliques
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"@type": "Question",
"name": "Comment diagnostiquer une dysfonction des N-méthyltransférases ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests génétiques et des analyses biochimiques peuvent être utilisés pour diagnostiquer."
}
},
{
"@type": "Question",
"name": "Quels tests sont utilisés pour évaluer l'activité enzymatique ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests enzymatiques spécifiques mesurent l'activité des N-méthyltransférases dans les échantillons."
}
},
{
"@type": "Question",
"name": "Y a-t-il des biomarqueurs associés à ces enzymes ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des biomarqueurs comme la méthylation de l'arginine peuvent indiquer une activité enzymatique."
}
},
{
"@type": "Question",
"name": "Quels symptômes peuvent indiquer un problème enzymatique ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des symptômes variés comme des troubles neurologiques ou immunitaires peuvent survenir."
}
},
{
"@type": "Question",
"name": "Comment les tests génétiques aident-ils au diagnostic ?",
"position": 5,
"acceptedAnswer": {
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{
"@type": "Question",
"name": "Quels sont les symptômes d'une carence en N-méthyltransférases ?",
"position": 6,
"acceptedAnswer": {
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"text": "Les symptômes incluent fatigue, troubles cognitifs et anomalies immunitaires."
}
},
{
"@type": "Question",
"name": "Les troubles de l'humeur sont-ils liés à ces enzymes ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des déséquilibres peuvent affecter l'humeur et contribuer à des troubles psychiatriques."
}
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{
"@type": "Question",
"name": "Peut-on observer des symptômes neurologiques ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des troubles neurologiques comme des convulsions peuvent être présents."
}
},
{
"@type": "Question",
"name": "Y a-t-il des symptômes spécifiques chez les enfants ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les enfants peuvent présenter des retards de développement et des troubles d'apprentissage."
}
},
{
"@type": "Question",
"name": "Comment les symptômes varient-ils selon l'âge ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes peuvent être plus prononcés chez les jeunes enfants et les personnes âgées."
}
},
{
"@type": "Question",
"name": "Comment prévenir les troubles liés aux N-méthyltransférases ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation équilibrée et un mode de vie sain peuvent aider à prévenir ces troubles."
}
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{
"@type": "Question",
"name": "Y a-t-il des mesures préventives spécifiques ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des dépistages précoces et des conseils génétiques peuvent être bénéfiques."
}
},
{
"@type": "Question",
"name": "L'éducation sur la santé est-elle importante ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, sensibiliser les patients et les familles peut aider à identifier les symptômes tôt."
}
},
{
"@type": "Question",
"name": "Les vaccinations jouent-elles un rôle préventif ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines vaccinations peuvent prévenir des infections qui aggravent les symptômes."
}
},
{
"@type": "Question",
"name": "Comment le suivi médical aide-t-il à la prévention ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un suivi régulier permet de surveiller l'état de santé et d'ajuster les traitements."
}
},
{
"@type": "Question",
"name": "Quels traitements existent pour les dysfonctionnements enzymatiques ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements peuvent inclure des suppléments nutritionnels et des thérapies ciblées."
}
},
{
"@type": "Question",
"name": "Les médicaments peuvent-ils aider à réguler ces enzymes ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certains médicaments peuvent moduler l'activité des N-méthyltransférases."
}
},
{
"@type": "Question",
"name": "Y a-t-il des thérapies géniques disponibles ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des recherches sont en cours sur les thérapies géniques pour corriger les mutations."
}
},
{
"@type": "Question",
"name": "Comment la nutrition influence-t-elle le traitement ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation riche en nutriments peut soutenir la fonction enzymatique."
}
},
{
"@type": "Question",
"name": "Les traitements sont-ils personnalisés ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les traitements peuvent être adaptés en fonction des besoins individuels du patient."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec ces troubles ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications neurologiques, immunitaires et métaboliques peuvent se développer."
}
},
{
"@type": "Question",
"name": "Les troubles cardiovasculaires sont-ils possibles ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des déséquilibres peuvent augmenter le risque de maladies cardiovasculaires."
}
},
{
"@type": "Question",
"name": "Comment les complications affectent-elles la qualité de vie ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles peuvent entraîner des limitations fonctionnelles et des besoins de soins accrus."
}
},
{
"@type": "Question",
"name": "Y a-t-il des complications à long terme ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des complications chroniques peuvent affecter la santé globale et le bien-être."
}
},
{
"@type": "Question",
"name": "Les complications peuvent-elles être évitées ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines complications peuvent être évitées par un traitement précoce et approprié."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque associés ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent des antécédents familiaux, des mutations génétiques et des carences nutritionnelles."
}
},
{
"@type": "Question",
"name": "L'environnement joue-t-il un rôle ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des facteurs environnementaux comme la pollution peuvent influencer la fonction enzymatique."
}
},
{
"@type": "Question",
"name": "Le mode de vie affecte-t-il le risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un mode de vie sédentaire et une mauvaise alimentation augmentent le risque de troubles."
}
},
{
"@type": "Question",
"name": "Les infections peuvent-elles être un facteur de risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines infections peuvent exacerber les symptômes et augmenter le risque de complications."
}
},
{
"@type": "Question",
"name": "Y a-t-il des groupes à risque spécifiques ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les personnes avec des antécédents familiaux ou des troubles métaboliques sont plus à risque."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 23/03/2025
Contenu vérifié selon les dernières recommandations médicales
4 publications dans cette catégorie
Affiliations :
Department of Pharmaceutical and Biomedical Sciences, University of Georgia, Athens, GA 30602, United States. yzheng@uga.edu.
Publications dans "Protein-arginine N-methyltransferases" :
4 publications dans cette catégorie
Affiliations :
Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, British Columbia, Canada. Electronic address: adam.frankel@ubc.ca.
Publications dans "Protein-arginine N-methyltransferases" :
3 publications dans cette catégorie
Affiliations :
Department of Pharmacy, Epigenetic Med Chem Lab, University of Salerno, via Giovanni Paolo II 132, Fisciano ,I-84084 SA Italy.
Publications dans "Protein-arginine N-methyltransferases" :
3 publications dans cette catégorie
Affiliations :
Department of Pharmacy, Epigenetic Med Chem Lab, University of Salerno, via Giovanni Paolo II 132, Fisciano ,I-84084 SA Italy.
PhD Program in Drug Discovery and Development, University of Salerno, via Giovanni Paolo II 132, Fisciano ,I-84084 SA Italy.
Publications dans "Protein-arginine N-methyltransferases" :
3 publications dans cette catégorie
Affiliations :
Department of Pharmacy, Epigenetic Med Chem Lab, University of Salerno, via Giovanni Paolo II 132, Fisciano ,I-84084 SA Italy.
Publications dans "Protein-arginine N-methyltransferases" :
3 publications dans cette catégorie
Affiliations :
Department of Pharmacy, Epigenetic Med Chem Lab, University of Salerno, via Giovanni Paolo II 132, Fisciano ,I-84084 SA Italy.
Publications dans "Protein-arginine N-methyltransferases" :
3 publications dans cette catégorie
Affiliations :
Department of Pharmacy, Epigenetic Med Chem Lab, University of Salerno, via Giovanni Paolo II 132, Fisciano ,I-84084 SA Italy.
Publications dans "Protein-arginine N-methyltransferases" :
3 publications dans cette catégorie
Affiliations :
Department of Pharmacy, Epigenetic Med Chem Lab, University of Salerno, via Giovanni Paolo II 132, Fisciano ,I-84084 SA Italy.
Publications dans "Protein-arginine N-methyltransferases" :
3 publications dans cette catégorie
Affiliations :
Department of Pharmacy, Epigenetic Med Chem Lab, University of Salerno, via Giovanni Paolo II 132, Fisciano ,I-84084 SA Italy.
Publications dans "Protein-arginine N-methyltransferases" :
3 publications dans cette catégorie
Affiliations :
Department of Medicinal Chemistry and Molecular Pharmacology, Center for Cancer Research, Institute for Drug Discovery, Purdue University, West Lafayette, IN 47907, United States.
Publications dans "Protein-arginine N-methyltransferases" :
3 publications dans cette catégorie
Affiliations :
Department of Medicine, Rhode Island Hospital and Alpert Medical School, Brown University, Providence, RI, U.S.A.
Department of Nephrology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Publications dans "Protein-arginine N-methyltransferases" :
3 publications dans cette catégorie
Affiliations :
Department of Molecular Cell Biology, School of Medicine, Sungkyunkwan University, Suwon 16419, Korea.
Single Cell Network Research Center, Sungkyunkwan University, Suwon 16419, Korea.
Publications dans "Protein-arginine N-methyltransferases" :
2 publications dans cette catégorie
Affiliations :
Department of Pharmacy, Epigenetic Med Chem Lab, University of Salerno, via Giovanni Paolo II 132, Fisciano ,I-84084 SA Italy.
PhD Program in Drug Discovery and Development, University of Salerno, via Giovanni Paolo II 132, Fisciano ,I-84084 SA Italy.
Publications dans "Protein-arginine N-methyltransferases" :
2 publications dans cette catégorie
Affiliations :
Department of Chemistry and Biochemistry, and the Molecular Biology Institute, University of California, Los Angeles, California 90095, United States.
Publications dans "Protein-arginine N-methyltransferases" :
2 publications dans cette catégorie
Affiliations :
Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Publications dans "Protein-arginine N-methyltransferases" :
2 publications dans cette catégorie
Affiliations :
Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Veterans Affairs Pittsburgh Healthcare system, Pittsburgh, Pennsylvania, USA.
Publications dans "Protein-arginine N-methyltransferases" :
2 publications dans cette catégorie
Affiliations :
Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Publications dans "Protein-arginine N-methyltransferases" :
2 publications dans cette catégorie
Affiliations :
Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Veterans Affairs Pittsburgh Healthcare system, Pittsburgh, Pennsylvania, USA.
Publications dans "Protein-arginine N-methyltransferases" :
2 publications dans cette catégorie
Affiliations :
Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Publications dans "Protein-arginine N-methyltransferases" :
2 publications dans cette catégorie
Affiliations :
Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Publications dans "Protein-arginine N-methyltransferases" :
A variety of three-dimensional (3D) printing techniques and materials facilitate the creation of customized models that promise to improve surgical procedures and patient outcomes. Three-dimensional-p...
To analyze, in vitro, the dimensional stability over time of 3D-printed surgical guides....
Ten surgical guides, manufactured by digital light processing 3D-printing technology, were scanned immediately after post-processing and then after 5, 10, 15, and 20 days. The corresponding standard t...
MAD of the teeth intaglio surface showed less variation (minimum: 0.002, maximum: 0.014 mm) than that of the mucosa (minimum: 0.026, maximum: 0.074 mm). Axial variations of the sleeves' housings on th...
Within the limitations of the experimental design, postmanufacturing dimensional variations of surgical guides were statistically significant. Although limited, they are an additional source of variab...
Digital technology is one of the major advancements during the past years that changed many aspects of our daily life. Medicine and dentistry were positively affected from the very first years of this...
The three-dimensional (3D) printing technology has remarkable potential as an auxiliary tool for representing anatomical structures, facilitating diagnosis and therapy, and enhancing training and teac...
The women suspected with congenital uterine anomalies (CUAs) were enrolled in the study. The diagnose of CUAs were made by 3D-TVS scanning and further confirmed under the hysteroscopy examination. One...
3D printing models of normal uterus, incomplete septate uterus, complete septate uterus, uterus didelphys and unicornuate uterus were produced on ultrasonographic data of 3D-TVS....
Our research and practice made the first try in modeling CUAs successfully based on ultrasonographic data entirely, verifying that it's a feasible way to build 3D printed models of high-quality throug...
Repair and reconstruction of the myopectineal orifice area using meshes is the mainstay of surgical treatment of inguinal hernias. However, the limitations of existing meshes are becoming increasingly...
High-fidelity models are required for technical mastery of bronchoscopic procedures in the fields of anaesthesia, intensive care, surgery and respiratory medicine. Our group has created a three-dimens...
Orthodontic digitalization has progressed steadily. Recently, three-dimensional metal printing has revolutionized the way appliances are designed and manufactured. The process offers several advantage...
Intraoral scanning techniques, and the associated software, have revolutionized model acquisition, analysis, and virtual planning in orthodontics. Three-dimensional printing is the final aspect of thi...
To relate the creation and expert validation (face and content validity) of an affordable three-dimensional (3-D) printed model of temporal bones with chronic otitis media with cholesteatoma (COMC) as...
We performed computed tomography (CT) of the temporal bones of a patient with COMC followed at the University of São Paulo (USP) Hospital with 3-D Slicer to create a 3-D model of the affected bone usi...
Otologists consistently scored the model positively for fidelity, educational value, reactions, and the overall model quality. Nine otologists agreed that the model was a good educational device for s...
Using 3-D printing technology, we created the first anatomically accurate, low-cost, disease-reproducing 3-D model of temporal bones for mastoidectomy training for cholesteatoma....
The functionalities of peptide microstructures and nanostructures can be enhanced by controlling their crystallinity. Gaining control over the crystallinity within the desired structure, however, rema...