questionsmedicales.fr
Acides nucléiques, nucléotides et nucléosides
Acides nucléiques
ARN
ARN : Questions médicales fréquentes
Termes MeSH sélectionnés :
Mendelian Randomization Analysis
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"@type": "Question",
"name": "Quelles complications des infections à ARN ?",
"position": 21,
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{
"@type": "Question",
"name": "L'ARN peut-il causer des maladies auto-immunes ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines infections à ARN sont associées à des maladies auto-immunes."
}
},
{
"@type": "Question",
"name": "Des complications neurologiques possibles ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des infections à ARN peuvent entraîner des complications neurologiques graves."
}
},
{
"@type": "Question",
"name": "Les infections à ARN peuvent-elles être mortelles ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines infections virales à ARN peuvent entraîner des décès, surtout chez les vulnérables."
}
},
{
"@type": "Question",
"name": "Des complications à long terme après une infection ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des symptômes persistants comme la fatigue peuvent survenir après l'infection."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque d'infections à ARN ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Âge avancé, immunodépression et conditions médicales préexistantes augmentent le risque."
}
},
{
"@type": "Question",
"name": "Le mode de vie influence-t-il le risque ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le tabagisme et une mauvaise hygiène augmentent le risque d'infections."
}
},
{
"@type": "Question",
"name": "Les voyages augmentent-ils le risque d'infection ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, voyager dans des zones à forte incidence d'infections à ARN augmente le risque."
}
},
{
"@type": "Question",
"name": "Les contacts avec des animaux sont-ils un risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certains virus à ARN peuvent être transmis par des animaux à l'homme."
}
},
{
"@type": "Question",
"name": "Les conditions de vie affectent-elles le risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, vivre dans des environnements surpeuplés augmente le risque d'infections."
}
}
]
}
]
}
└─
ARN circulaire
RNA, Circular
D000079962 -
D13.444.735.032
└─
Isoformes d'ARN
RNA Isoforms
D059368 -
D13.444.735.064
└─
ARN des algues
RNA, Algal
D048030 -
D13.444.735.130
└─
ARN des archées
RNA, Archaeal
D019642 -
D13.444.735.300
└─
ARN bactérien
RNA, Bacterial
D012329 -
D13.444.735.473
└─
ARN fongique
RNA, Fungal
D012331 -
D13.444.735.500
└─
ARN des helminthes
RNA, Helminth
D018510 -
D13.444.735.520
└─
ARN messager
RNA, Messenger
D012333 -
D13.444.735.544
└─
ARN mitochondrial
RNA, Mitochondrial
D000077278 -
D13.444.735.580
└─
ARN tumoral
RNA, Neoplasm
D012334 -
D13.444.735.615
└─
ARN nucléaire
RNA, Nuclear
D015138 -
D13.444.735.628
└─
ARN des plantes
RNA, Plant
D018749 -
D13.444.735.635
└─
Précurseurs des ARN
RNA Precursors
D012322 -
D13.444.735.640
└─
ARN des protozoaires
RNA, Protozoan
D016053 -
D13.444.735.650
└─
ARN ribosomique
RNA, Ribosomal
D012335 -
D13.444.735.686
└─
ARN satellite
RNA, Satellite
D019244 -
D13.444.735.721
└─
ARN de transfert
RNA, Transfer
D012343 -
D13.444.735.757
└─
ARN non traduit
RNA, Untranslated
D022661 -
D13.444.735.790
└─
ARN viral
RNA, Viral
D012367 -
D13.444.735.828
└─└─
ARN messager stocké
RNA, Messenger, Stored
D023121 -
D13.444.735.544.527
└─└─
ARN nucléaire hétérogène
RNA, Heterogeneous Nuclear
D012332 -
D13.444.735.628.806
└─└─
ARN des chloroplastes
RNA, Chloroplast
D018747 -
D13.444.735.635.575
└─└─
ARN ribosomique 5S
RNA, Ribosomal, 5S
D012341 -
D13.444.735.686.650
└─└─
ARN ribosomique 5.8S
RNA, Ribosomal, 5.8S
D012340 -
D13.444.735.686.660
└─└─
ARN ribosomique 16S
RNA, Ribosomal, 16S
D012336 -
D13.444.735.686.670
└─└─
ARN ribosomique 18S
RNA, Ribosomal, 18S
D012337 -
D13.444.735.686.675
└─└─
ARN ribosomique 23S
RNA, Ribosomal, 23S
D012338 -
D13.444.735.686.680
└─└─
ARN ribosomique 28S
RNA, Ribosomal, 28S
D012339 -
D13.444.735.686.690
└─└─
Introns autoépissables d'ARN ribosomique
RNA, Ribosomal, Self-Splicing
D044563 -
D13.444.735.686.845
└─└─
Satellite du virus de la mosaïque du concombre
Cucumber Mosaic Virus Satellite
D019401 -
D13.444.735.721.250
└─└─
ARN de transfert spécifiques des différents acides aminés
RNA, Transfer, Amino Acid-Specific
D012345 -
D13.444.735.757.700
└─└─
ARN de transfert aminoacylés
RNA, Transfer, Amino Acyl
D012346 -
D13.444.735.757.715
└─└─
ARN catalytique
RNA, Catalytic
D016337 -
D13.444.735.790.199
└─└─
ARN long non codant
RNA, Long Noncoding
D062085 -
D13.444.735.790.375
└─└─
Petit ARN non traduit
RNA, Small Untranslated
D058727 -
D13.444.735.790.552
└─└─
ARN subgénomique
Subgenomic RNA
D000094762 -
D13.444.735.828.500
└─└─└─
ARN de transfert de l'alanine
RNA, Transfer, Ala
D012344 -
D13.444.735.757.700.050
└─└─└─
ARN de transfert de l'arginine
RNA, Transfer, Arg
D012347 -
D13.444.735.757.700.075
└─└─└─
ARN de transfert de l'asparagine
RNA, Transfer, Asn
D012348 -
D13.444.735.757.700.085
└─└─└─
ARN de transfert de l'acide aspartique
RNA, Transfer, Asp
D012349 -
D13.444.735.757.700.090
└─└─└─
ARN de transfert de la cystéine
RNA, Transfer, Cys
D012350 -
D13.444.735.757.700.200
└─└─└─
ARN de transfert de la glutamine
RNA, Transfer, Gln
D012351 -
D13.444.735.757.700.400
└─└─└─
ARN de transfert de l'acide glutamique
RNA, Transfer, Glu
D012352 -
D13.444.735.757.700.410
└─└─└─
ARN de transfert de la glycine
RNA, Transfer, Gly
D012353 -
D13.444.735.757.700.420
└─└─└─
ARN de transfert de l'histidine
RNA, Transfer, His
D012354 -
D13.444.735.757.700.450
└─└─└─
ARN de transfert de l'isoleucine
RNA, Transfer, Ile
D012355 -
D13.444.735.757.700.480
└─└─└─
ARN de transfert de la leucine
RNA, Transfer, Leu
D012356 -
D13.444.735.757.700.500
└─└─└─
ARN de transfert de la lysine
RNA, Transfer, Lys
D012357 -
D13.444.735.757.700.510
└─└─└─
ARN de transfert de la méthionine
RNA, Transfer, Met
D012358 -
D13.444.735.757.700.525
└─└─└─
ARN de transfert de la phénylalanine
RNA, Transfer, Phe
D012360 -
D13.444.735.757.700.650
└─└─└─
ARN de transfert de la proline
RNA, Transfer, Pro
D012361 -
D13.444.735.757.700.660
└─└─└─
ARN de transfert de la sérine
RNA, Transfer, Ser
D012362 -
D13.444.735.757.700.700
└─└─└─
ARN de transfert de la thréonine
RNA, Transfer, Thr
D012363 -
D13.444.735.757.700.725
└─└─└─
ARN de transfert du tryptophane
RNA, Transfer, Trp
D012364 -
D13.444.735.757.700.740
└─└─└─
ARN de transfert de la tyrosine
RNA, Transfer, Tyr
D012365 -
D13.444.735.757.700.750
└─└─└─
ARN de transfert de la valine
RNA, Transfer, Val
D012366 -
D13.444.735.757.700.900
└─└─└─
microARN
MicroRNAs
D035683 -
D13.444.735.790.552.500
└─└─└─
Systèmes CRISPR-Cas, ARN, guide
RNA, Guide, CRISPR-Cas Systems
D000094704 -
D13.444.735.790.552.563
└─└─└─
ARN guide
RNA, Guide, Kinetoplastida
D017394 -
D13.444.735.790.552.625
└─└─└─
Petit ARN cytoplasmique
RNA, Small Cytoplasmic
D020733 -
D13.444.735.790.552.750
└─└─└─
Petit ARN interférent
RNA, Small Interfering
D034741 -
D13.444.735.790.552.875
└─└─└─
Petit ARN nucléaire
RNA, Small Nuclear
D012342 -
D13.444.735.790.552.937
└─└─└─
ARN de tête épissé
RNA, Spliced Leader
D020038 -
D13.444.735.790.552.968
└─└─└─└─
MicroARN circulant
Circulating MicroRNA
D000074166 -
D13.444.735.790.552.500.500
└─└─└─└─
ARN interagissant avec Piwi
Piwi-Interacting RNA
D000094322 -
D13.444.735.790.552.875.500
└─└─└─└─
Petit ARN nucléolaire
RNA, Small Nucleolar
D020537 -
D13.444.735.790.552.937.800
Infection with...
Utilizing summary data from genome-wide association studies, we employed a two-sample Mendelian randomization method to investigate the association between 731 immunophenotypes and syphilis. Syphilis ...
Our findings revealed that 33, 36, and 27 immunophenotypes of peripheral blood were associated with syphilis (regardless of disease stage), early syphilis and late syphilis, respectively. Subsequent a...
Multiple immunophenotypes demonstrated associations with syphilis, showcasing substantial disparities between the early and late stages of the disease. These findings hold promise for informing immuno...
This study was conducted to evaluate the potential causality association of SOCS3 methylation with abdominal obesity using Mendelian randomization. A case-control study, including 1064 participants, w...
Whether the quantity and quality of sleep are the risk factors for the development of Parkinson's disease remains unclear though it has now been confirmed that the quality of sleep among patients with...
The summary-level data collected from the published genome-wide association studies was used for analysis. Besides, the genetic relationships between different sleep-related phenotypes, including self...
In general, there was insufficient evidence to support the causal effect of sleep-related phenotypes on risk (N cases/controls = 33,674/449,056) and age at the onset (N cases = 28,568) of Parkinson's ...
The results of this study suggest that insomnia-associated single nucleotide polymorphisms are more frequent in later onset Parkinson's disease patients compared to earlier onset patients. However, gi...
Emerging evidence suggests a tentative association between cathepsins and uterine leiomyoma (UL). Previous investigations have predominantly focused on the role of cathepsins in the metastasis and col...
The causal relationship between childhood obesity and hypertension in pregnancy remains unclear. To examine the causal association between childhood obesity and hypertension in pregnancy, two-sample M...
Single-nucleotide polymorphisms (SNPs) associated with childhood obesity were obtained from a published genome-wide association study (GWAS) of 13 848 European individuals. Summary-level data for hype...
Genetically determined childhood obesity significantly affects hypertension in pregnancy by IVW [odds ratio (OR) = 1.161, 95% confidence interval (CI) 1.086-1.039; P = 9.92 × 10 -6 ] and weighted medi...
A causal effect between genetically predicted childhood obesity and the risk of hypertension in pregnancy was identified. The prevention of hypertension in pregnancy should be promoted in populations ...
This analysis assessed the putative causal association between genetically predicted percent body fat and areal bone mineral density (aBMD) and, more specifically, the association between genetically ...
Mendelian randomization was used to assess the relationship of MFA and percent body fat with whole-body, lumbar spine, femoral neck, and forearm aBMD. Sex-stratified and age-stratified exploratory ana...
In all MR analyses, genetically predicted MFA was inversely associated with aBMD for the whole body (β = -0.053, p = 0.0002), lumbar spine (β = -0.075; p = 0.0001), femoral neck (β = -0.045; p = 0.008...
This study did not support the hypothesis that MFA protects against low aBMD. Instead, it showed that MFA may result in lower aBMD. Further research is needed to understand how MFA affects aBMD and ot...
A large number of observational studies showed that patients with psoriasis have a higher risk of cardiovascular disease (CVD), but most studies did not fully adjust for confounding factors, so it is ...
We used genetic instruments from the genome-wide association study (GWAS) of European descent for psoriasis to investigate its relationship with CVD. Inverse variance-weighted (IVW) MR analyses were u...
The fixed-effects IVW method indicated that genetic susceptibility to psoriasis was associated with a higher risk of heart failure (HF) [odds ratio (OR) = 1.04; 95% CI, 1.01-1.06, P = 2.72E-03], atria...
Our study provided evidence for a potential causal link between psoriasis and CVD. These findings partly suggest that early monitoring of cardiovascular risk in patients with psoriasis is intentional....
The immune microenvironment assumes a significant role in the pathogenesis of osteoarthritis (OA). However, the current biomarkers for the diagnosis and treatment of OA are not satisfactory. Our study...
The discovery dataset integrated the GSE89408 and GSE143514 datasets to identify biomarkers that were significantly associated with the OA immune microenvironment through multiple machine learning met...
Three signature genes (FCER1G, HLA-DMB, and HHLA-DPA1) associated with the OA immune microenvironment were identified as having good diagnostic performances, which can be used as biomarkers. MR result...
The present study identified the 3 potential immune-related biomarkers for OA, providing new perspectives for the prevention and treatment of OA. The MR study provides genetic support for the causal e...
There is little evidence on the genetic associations between life-course adiposity (including birth weight, childhood BMI, and adulthood BMI) and severe liver disease (SLD; including cirrhosis and liv...
Genetic variants were obtained from genome-wide association studies. Two-sample Mendelian randomization (MR) analyses were performed to assess the genetic associations of life-course adiposity with SL...
In observational analyses, genetic predispositions to childhood adiposity and adulthood adiposity were each associated with SLD. There was a U-shaped association between adulthood weight change and ri...
The current study provided genetic evidence on the associations between life-course adiposity and SLD....
The VITAL trial of vitamin D supplementation suggested a possible protective effect for autoimmune diseases but uncertainties remain. We investigated potential causal effects of vitamin D on composite...
We used data from 332,984 participants of the UK Biobank of whom 23,089 had at least one autoimmune disease defined using ICD code and/or self-report. Diseases were further considered in mechanistic s...
Genetically-predicted vitamin D was associated with lower risk of diseases in the autoinflammation group (OR 0.95 per 10 ng/ml increase in 25-hydroxycholecalciferol; 95%CI 0.91-0.99; p = 0.03) but not...
We found genetic evidence to support a causal link between 25-hydroxycholecalciferol concentrations and psoriasis and systemic lupus erythematosus. These results have implications for potential diseas...
