Titre : Protéines mitochondriales

Protéines mitochondriales : Questions médicales fréquentes

Nom anglais: Mitochondrial Proteins

Descriptor UI: D024101

Tree Number: D12.776.575

Termes MeSH sélectionnés :

Network Meta-Analysis

Questions fréquentes et termes MeSH associés

Diagnostic 5

#1

Comment diagnostiquer une dysfonction mitochondriale ?

Un diagnostic peut inclure des tests génétiques, des biopsies musculaires et des analyses biochimiques.
Dysfonction mitochondriale Biopsie musculaire
#2

Quels tests sanguins sont utilisés pour évaluer les protéines mitochondriales ?

Des tests de lactate, pyruvate et des enzymes spécifiques peuvent être effectués.
Lactate Enzymes
#3

Quels symptômes indiquent une maladie mitochondriale ?

Fatigue, faiblesse musculaire, troubles neurologiques et problèmes cardiaques peuvent indiquer une maladie.
Fatigue Maladies mitochondriales
#4

Les tests génétiques sont-ils fiables pour les maladies mitochondriales ?

Oui, les tests génétiques peuvent identifier des mutations spécifiques liées aux maladies mitochondriales.
Tests génétiques Mutations
#5

Quel rôle joue l'imagerie dans le diagnostic mitochondrial ?

L'imagerie par résonance magnétique (IRM) peut aider à visualiser des anomalies cérébrales.
Imagerie par résonance magnétique Anomalies cérébrales

Symptômes 5

#1

Quels sont les symptômes courants des maladies mitochondriales ?

Les symptômes incluent fatigue, douleurs musculaires, troubles de la vision et épilepsie.
Fatigue Épilepsie
#2

Les troubles cognitifs sont-ils liés aux protéines mitochondriales ?

Oui, des troubles cognitifs peuvent survenir en raison de dysfonctionnements mitochondriaux.
Troubles cognitifs Dysfonction mitochondriale
#3

Comment la myopathie mitochondriale se manifeste-t-elle ?

Elle se manifeste par une faiblesse musculaire, des crampes et une intolérance à l'exercice.
Myopathie mitochondriale Faiblesse musculaire
#4

Les troubles cardiaques sont-ils fréquents dans les maladies mitochondriales ?

Oui, des cardiomyopathies peuvent se développer en raison de dysfonctionnements mitochondriaux.
Cardiomyopathies Dysfonctionnements mitochondriaux
#5

Les symptômes varient-ils selon l'âge d'apparition ?

Oui, les symptômes peuvent varier considérablement selon l'âge d'apparition de la maladie.
Âge d'apparition Variabilité des symptômes

Prévention 5

#1

Peut-on prévenir les maladies mitochondriales ?

Certaines maladies génétiques ne peuvent pas être prévenues, mais un mode de vie sain aide.
Prévention Mode de vie sain
#2

L'exercice physique peut-il réduire les risques ?

Oui, l'exercice régulier peut améliorer la santé mitochondriale et réduire les risques.
Exercice physique Santé mitochondriale
#3

Les antioxydants jouent-ils un rôle préventif ?

Oui, les antioxydants peuvent protéger les mitochondries des dommages oxydatifs.
Antioxydants Dommages oxydatifs
#4

Une alimentation équilibrée est-elle importante ?

Oui, une alimentation riche en nutriments soutient la santé mitochondriale.
Alimentation équilibrée Nutriments
#5

Les dépistages précoces sont-ils recommandés ?

Oui, le dépistage précoce peut aider à identifier les risques et à intervenir rapidement.
Dépistage précoce Intervention rapide

Traitements 5

#1

Quels traitements sont disponibles pour les maladies mitochondriales ?

Les traitements incluent des suppléments, des thérapies symptomatiques et des approches nutritionnelles.
Suppléments Thérapies symptomatiques
#2

Les coenzymes Q10 sont-elles bénéfiques ?

Oui, le coenzyme Q10 peut améliorer la fonction mitochondriale et réduire les symptômes.
Coenzyme Q10 Fonction mitochondriale
#3

La thérapie génique est-elle une option pour ces maladies ?

La thérapie génique est en recherche, mais elle pourrait offrir des solutions futures.
Thérapie génique Recherche
#4

Les régimes alimentaires peuvent-ils aider ?

Oui, des régimes spécifiques peuvent soutenir la fonction mitochondriale et améliorer les symptômes.
Régimes alimentaires Fonction mitochondriale
#5

Les traitements varient-ils selon le type de maladie mitochondriale ?

Oui, les traitements doivent être adaptés au type spécifique de maladie mitochondriale.
Types de maladies mitochondriales Adaptation des traitements

Complications 5

#1

Quelles complications peuvent survenir avec les maladies mitochondriales ?

Les complications incluent des troubles neurologiques, cardiaques et endocriniens.
Complications Troubles neurologiques
#2

Les maladies mitochondriales peuvent-elles affecter la fertilité ?

Oui, certaines maladies mitochondriales peuvent entraîner des problèmes de fertilité.
Fertilité Maladies mitochondriales
#3

Les complications peuvent-elles être gérées ?

Certaines complications peuvent être gérées avec des traitements symptomatiques appropriés.
Gestion des complications Traitements symptomatiques
#4

Les maladies mitochondriales augmentent-elles le risque de cancer ?

Certaines études suggèrent un lien entre dysfonction mitochondriale et risque accru de cancer.
Risque de cancer Dysfonction mitochondriale
#5

Les complications cardiovasculaires sont-elles fréquentes ?

Oui, les maladies mitochondriales peuvent entraîner des cardiomyopathies et d'autres complications.
Complications cardiovasculaires Cardiomyopathies

Facteurs de risque 5

#1

Quels sont les facteurs de risque pour les maladies mitochondriales ?

Les facteurs incluent des antécédents familiaux, des mutations génétiques et des expositions environnementales.
Antécédents familiaux Mutations génétiques
#2

L'âge est-il un facteur de risque ?

Oui, certaines maladies mitochondriales se manifestent plus fréquemment avec l'âge.
Âge Maladies mitochondriales
#3

Les facteurs environnementaux influencent-ils les maladies mitochondriales ?

Oui, l'exposition à des toxines peut augmenter le risque de dysfonction mitochondriale.
Facteurs environnementaux Toxines
#4

Le stress oxydatif est-il un facteur de risque ?

Oui, le stress oxydatif peut endommager les mitochondries et contribuer à des maladies.
Stress oxydatif Dommages mitochondriaux
#5

Les habitudes alimentaires peuvent-elles influencer le risque ?

Oui, une alimentation pauvre en nutriments peut augmenter le risque de dysfonction mitochondriale.
Habitudes alimentaires Dysfonction mitochondriale
{ "@context": "https://schema.org", "@graph": [ { "@type": "MedicalWebPage", "name": "Protéines mitochondriales : Questions médicales les plus fréquentes", "headline": "Protéines mitochondriales : Comprendre les symptômes, diagnostics et traitements", "description": "Guide complet et accessible sur les Protéines mitochondriales : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.", "datePublished": "2024-04-12", "dateModified": "2025-04-07", "inLanguage": "fr", "medicalAudience": [ { "@type": "MedicalAudience", "name": "Grand public", "audienceType": "Patient", "healthCondition": { "@type": "MedicalCondition", "name": "Protéines mitochondriales" }, "suggestedMinAge": 18, "suggestedGender": "unisex" }, { "@type": "MedicalAudience", "name": "Médecins", "audienceType": "Physician", "geographicArea": { "@type": "AdministrativeArea", "name": "France" } }, { "@type": "MedicalAudience", "name": "Chercheurs", "audienceType": "Researcher", "geographicArea": { "@type": "AdministrativeArea", "name": "International" } } ], "reviewedBy": { "@type": "Person", "name": "Dr Olivier Menir", "jobTitle": "Expert en Médecine", "description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale", "url": "/static/pages/docteur-olivier-menir.html", "alumniOf": { "@type": "EducationalOrganization", "name": "Université Paris Descartes" } }, "isPartOf": { "@type": "MedicalWebPage", "name": "Protéines", "url": "https://questionsmedicales.fr/mesh/D011506", "about": { "@type": "MedicalCondition", "name": "Protéines", "code": { "@type": "MedicalCode", "code": "D011506", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D12.776" } } }, "hasPart": [ { "@type": "MedicalWebPage", "name": "Aldehyde dehydrogenase, mitochondrial", "alternateName": "Aldehyde Dehydrogenase, Mitochondrial", "url": "https://questionsmedicales.fr/mesh/D000071396", "about": { "@type": "MedicalCondition", "name": "Aldehyde dehydrogenase, mitochondrial", "code": { "@type": "MedicalCode", "code": "D000071396", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D12.776.575.093" } } }, { "@type": "MedicalWebPage", "name": "Mitochondrial creatine kinase", "alternateName": "Creatine Kinase, Mitochondrial Form", "url": "https://questionsmedicales.fr/mesh/D052281", "about": { "@type": "MedicalCondition", "name": "Mitochondrial creatine kinase", "code": { "@type": "MedicalCode", "code": "D052281", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D12.776.575.186" } } }, { "@type": "MedicalWebPage", "name": "DNA Polymerase gamma", "alternateName": "DNA Polymerase gamma", "url": "https://questionsmedicales.fr/mesh/D000074002", "about": { "@type": "MedicalCondition", "name": "DNA Polymerase gamma", "code": { "@type": "MedicalCode", "code": "D000074002", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D12.776.575.280" } } }, { "@type": "MedicalWebPage", "name": "Ferrochelatase", "alternateName": "Ferrochelatase", "url": "https://questionsmedicales.fr/mesh/D005294", "about": { "@type": "MedicalCondition", "name": "Ferrochelatase", "code": { "@type": "MedicalCode", "code": "D005294", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D12.776.575.562" } } }, { "@type": "MedicalWebPage", "name": "Protéines de transport de la membrane mitochondriale", "alternateName": "Mitochondrial Membrane Transport Proteins", "url": "https://questionsmedicales.fr/mesh/D033681", "about": { "@type": "MedicalCondition", "name": "Protéines de transport de la membrane mitochondriale", "code": { "@type": "MedicalCode", "code": "D033681", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D12.776.575.750" } }, "hasPart": [ { "@type": "MedicalWebPage", "name": "Mitochondrial ADP, ATP Translocases", "alternateName": "Mitochondrial ADP, ATP Translocases", "url": "https://questionsmedicales.fr/mesh/D000226", "about": { "@type": "MedicalCondition", "name": "Mitochondrial ADP, ATP Translocases", "code": { "@type": "MedicalCode", "code": "D000226", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D12.776.575.750.500" } }, "hasPart": [ { "@type": "MedicalWebPage", "name": "Translocateur-1 de nucléotides adényliques", "alternateName": "Adenine Nucleotide Translocator 1", "url": "https://questionsmedicales.fr/mesh/D033741", "about": { "@type": "MedicalCondition", "name": "Translocateur-1 de nucléotides adényliques", "code": { "@type": "MedicalCode", "code": "D033741", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D12.776.575.750.500.100" } } }, { "@type": "MedicalWebPage", "name": "Translocateur-2 de nucléotides adényliques", "alternateName": "Adenine Nucleotide Translocator 2", "url": "https://questionsmedicales.fr/mesh/D033742", "about": { "@type": "MedicalCondition", "name": "Translocateur-2 de nucléotides adényliques", "code": { "@type": "MedicalCode", "code": "D033742", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D12.776.575.750.500.200" } } }, { "@type": "MedicalWebPage", "name": "Translocateur-3 de nucléotides adényliques", "alternateName": "Adenine Nucleotide Translocator 3", "url": "https://questionsmedicales.fr/mesh/D033781", "about": { "@type": "MedicalCondition", "name": "Translocateur-3 de nucléotides adényliques", "code": { "@type": "MedicalCode", "code": "D033781", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D12.776.575.750.500.300" } } } ] }, { "@type": "MedicalWebPage", "name": "Translocateur-1 de nucléotides adényliques", "alternateName": "Adenine Nucleotide Translocator 1", "url": "https://questionsmedicales.fr/mesh/D033741", "about": { "@type": "MedicalCondition", "name": "Translocateur-1 de nucléotides adényliques", "code": { "@type": "MedicalCode", "code": "D033741", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D12.776.575.750.500.100" } } }, { "@type": "MedicalWebPage", "name": "Translocateur-2 de nucléotides adényliques", "alternateName": "Adenine Nucleotide Translocator 2", "url": "https://questionsmedicales.fr/mesh/D033742", "about": { "@type": "MedicalCondition", "name": "Translocateur-2 de nucléotides adényliques", "code": { "@type": "MedicalCode", "code": "D033742", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D12.776.575.750.500.200" } } }, { "@type": "MedicalWebPage", "name": "Translocateur-3 de nucléotides adényliques", "alternateName": "Adenine Nucleotide Translocator 3", "url": "https://questionsmedicales.fr/mesh/D033781", "about": { "@type": "MedicalCondition", "name": "Translocateur-3 de nucléotides adényliques", "code": { "@type": "MedicalCode", "code": "D033781", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D12.776.575.750.500.300" } } }, { "@type": "MedicalWebPage", "name": "Pore de transition de perméabilité mitochondriale", "alternateName": "Mitochondrial Permeability Transition Pore", "url": "https://questionsmedicales.fr/mesh/D000083162", "about": { "@type": "MedicalCondition", "name": "Pore de transition de perméabilité mitochondriale", "code": { "@type": "MedicalCode", "code": "D000083162", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D12.776.575.750.563" } } }, { "@type": "MedicalWebPage", "name": "Protéines du complexe d'import des protéines précurseurs mitochondriales", "alternateName": "Mitochondrial Precursor Protein Import Complex Proteins", "url": "https://questionsmedicales.fr/mesh/D000090622", "about": { "@type": "MedicalCondition", "name": "Protéines du complexe d'import des protéines précurseurs mitochondriales", "code": { "@type": "MedicalCode", "code": "D000090622", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D12.776.575.750.594" } } }, { "@type": "MedicalWebPage", "name": "Mitochondrial Proton-Translocating ATPases", "alternateName": "Mitochondrial Proton-Translocating ATPases", "url": "https://questionsmedicales.fr/mesh/D025261", "about": { "@type": "MedicalCondition", "name": "Mitochondrial Proton-Translocating ATPases", "code": { "@type": "MedicalCode", "code": "D025261", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D12.776.575.750.625" } } }, { "@type": "MedicalWebPage", "name": "Protéines de découplage mitochondrial", "alternateName": "Mitochondrial Uncoupling Proteins", "url": "https://questionsmedicales.fr/mesh/D000071245", "about": { "@type": "MedicalCondition", "name": "Protéines de découplage mitochondrial", "code": { "@type": "MedicalCode", "code": "D000071245", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D12.776.575.750.688" } }, "hasPart": [ { "@type": "MedicalWebPage", "name": "Protéine-1 de découplage", "alternateName": "Uncoupling Protein 1", "url": "https://questionsmedicales.fr/mesh/D000071256", "about": { "@type": "MedicalCondition", "name": "Protéine-1 de découplage", "code": { "@type": "MedicalCode", "code": "D000071256", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D12.776.575.750.688.500" } } }, { "@type": "MedicalWebPage", "name": "Protéine-2 de découplage", "alternateName": "Uncoupling Protein 2", "url": "https://questionsmedicales.fr/mesh/D000071246", "about": { "@type": "MedicalCondition", "name": "Protéine-2 de découplage", "code": { "@type": "MedicalCode", "code": "D000071246", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D12.776.575.750.688.750" } } }, { "@type": "MedicalWebPage", "name": "Protéine-3 de découplage", "alternateName": "Uncoupling Protein 3", "url": "https://questionsmedicales.fr/mesh/D000071247", "about": { "@type": "MedicalCondition", "name": "Protéine-3 de découplage", "code": { "@type": "MedicalCode", "code": "D000071247", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D12.776.575.750.688.875" } } } ] }, { "@type": "MedicalWebPage", "name": "Protéine-1 de découplage", "alternateName": "Uncoupling Protein 1", "url": "https://questionsmedicales.fr/mesh/D000071256", "about": { "@type": "MedicalCondition", "name": "Protéine-1 de découplage", "code": { "@type": "MedicalCode", "code": "D000071256", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D12.776.575.750.688.500" } } }, { "@type": "MedicalWebPage", "name": "Protéine-2 de découplage", "alternateName": "Uncoupling Protein 2", "url": "https://questionsmedicales.fr/mesh/D000071246", "about": { "@type": "MedicalCondition", "name": "Protéine-2 de découplage", "code": { "@type": "MedicalCode", "code": "D000071246", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D12.776.575.750.688.750" } } }, { "@type": "MedicalWebPage", "name": "Protéine-3 de découplage", "alternateName": "Uncoupling Protein 3", "url": "https://questionsmedicales.fr/mesh/D000071247", "about": { "@type": "MedicalCondition", "name": "Protéine-3 de découplage", "code": { "@type": "MedicalCode", "code": "D000071247", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D12.776.575.750.688.875" } } }, { "@type": "MedicalWebPage", "name": "Canal anionique-1 voltage-dépendant", "alternateName": "Voltage-Dependent Anion Channel 1", "url": "https://questionsmedicales.fr/mesh/D050995", "about": { "@type": "MedicalCondition", "name": "Canal anionique-1 voltage-dépendant", "code": { "@type": "MedicalCode", "code": "D050995", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D12.776.575.750.750" } } }, { "@type": "MedicalWebPage", "name": "Canal anionique-2 voltage-dépendant", "alternateName": "Voltage-Dependent Anion Channel 2", "url": "https://questionsmedicales.fr/mesh/D050996", "about": { "@type": "MedicalCondition", "name": "Canal anionique-2 voltage-dépendant", "code": { "@type": "MedicalCode", "code": "D050996", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D12.776.575.750.875" } } } ] }, { "@type": "MedicalWebPage", "name": "Protéine trifonctionnelle mitochondriale", "alternateName": "Mitochondrial Trifunctional Protein", "url": "https://questionsmedicales.fr/mesh/D063991", "about": { "@type": "MedicalCondition", "name": "Protéine trifonctionnelle mitochondriale", "code": { "@type": "MedicalCode", "code": "D063991", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D12.776.575.765" } }, "hasPart": [ { "@type": "MedicalWebPage", "name": "Sous-unité alpha de la protéine trifonctionnelle mitochondriale", "alternateName": "Mitochondrial Trifunctional Protein, alpha Subunit", "url": "https://questionsmedicales.fr/mesh/D063992", "about": { "@type": "MedicalCondition", "name": "Sous-unité alpha de la protéine trifonctionnelle mitochondriale", "code": { "@type": "MedicalCode", "code": "D063992", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D12.776.575.765.200" } } }, { "@type": "MedicalWebPage", "name": "Sous-unité bêta de la protéine trifonctionnelle mitochondriale", "alternateName": "Mitochondrial Trifunctional Protein, beta Subunit", "url": "https://questionsmedicales.fr/mesh/D063993", "about": { "@type": "MedicalCondition", "name": "Sous-unité bêta de la protéine trifonctionnelle mitochondriale", "code": { "@type": "MedicalCode", "code": "D063993", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D12.776.575.765.500" } } } ] }, { "@type": "MedicalWebPage", "name": "Nucleoside diphosphate kinase D", "alternateName": "Nucleoside Diphosphate Kinase D", "url": "https://questionsmedicales.fr/mesh/D061107", "about": { "@type": "MedicalCondition", "name": "Nucleoside diphosphate kinase D", "code": { "@type": "MedicalCode", "code": "D061107", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D12.776.575.781" } } }, { "@type": "MedicalWebPage", "name": "Peroxiredoxin III", "alternateName": "Peroxiredoxin III", "url": "https://questionsmedicales.fr/mesh/D061105", "about": { "@type": "MedicalCondition", "name": "Peroxiredoxin III", "code": { "@type": "MedicalCode", "code": "D061105", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D12.776.575.812" } } }, { "@type": "MedicalWebPage", "name": "Prohibitines", "alternateName": "Prohibitins", "url": "https://questionsmedicales.fr/mesh/D000091402", "about": { "@type": "MedicalCondition", "name": "Prohibitines", "code": { "@type": "MedicalCode", "code": "D000091402", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D12.776.575.844" } } }, { "@type": "MedicalWebPage", "name": "Sirtuine-3", "alternateName": "Sirtuin 3", "url": "https://questionsmedicales.fr/mesh/D056566", "about": { "@type": "MedicalCondition", "name": "Sirtuine-3", "code": { "@type": "MedicalCode", "code": "D056566", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D12.776.575.875" } } } ], "about": { "@type": "MedicalCondition", "name": "Protéines mitochondriales", "alternateName": "Mitochondrial Proteins", "code": { "@type": "MedicalCode", "code": "D024101", "codingSystem": "MeSH" } }, "author": [ { "@type": "Person", "name": "Thomas Becker", "url": "https://questionsmedicales.fr/author/Thomas%20Becker", "affiliation": { "@type": "Organization", "name": "Institute of Biochemistry und Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, 79104 Freiburg, Germany." } }, { "@type": "Person", "name": "Johannes M Herrmann", "url": "https://questionsmedicales.fr/author/Johannes%20M%20Herrmann", "affiliation": { "@type": "Organization", "name": "Cell Biology, University of Kaiserslautern, Kaiserslautern, Germany. Electronic address: hannes.herrmann@biologie.uni-kl.de." } }, { "@type": "Person", "name": "Timothy E Shutt", "url": "https://questionsmedicales.fr/author/Timothy%20E%20Shutt", "affiliation": { "@type": "Organization", "name": "Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada." } }, { "@type": "Person", "name": "Cole M Haynes", "url": "https://questionsmedicales.fr/author/Cole%20M%20Haynes", "affiliation": { "@type": "Organization", "name": "Molecular, Cell and Cancer Biology, UMass-Chan Medical School, Worcester, MA 01655, USA." } }, { "@type": "Person", "name": "Yang Yang", "url": "https://questionsmedicales.fr/author/Yang%20Yang", "affiliation": { "@type": "Organization", "name": "Stem Cells and Metabolism Research Program, Research Programs Unit, Faculty of Medicine, University of Helsinki, 00014 Helsinki, Finland." } } ], "citation": [ { "@type": "ScholarlyArticle", "name": "How To Read a Network Meta-analysis.", "datePublished": "2023-11-03", "url": "https://questionsmedicales.fr/article/37925328", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1016/j.euf.2023.10.018" } }, { "@type": "ScholarlyArticle", "name": "Methodological quality of network meta-analysis in dentistry: a meta-research.", "datePublished": "2023-07-10", "url": "https://questionsmedicales.fr/article/37436290", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1590/1807-3107bor-2023.vol37.0062" } }, { "@type": "ScholarlyArticle", "name": "Effects of non-pharmacological interventions for adults with subjective cognitive decline: a network meta-analysis and component network meta-analysis.", "datePublished": "2024-06-27", "url": "https://questionsmedicales.fr/article/38937777", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1186/s12916-024-03491-z" } }, { "@type": "ScholarlyArticle", "name": "Network meta-interpolation: Effect modification adjustment in network meta-analysis using subgroup analyses.", "datePublished": "2022-11-04", "url": "https://questionsmedicales.fr/article/36283960", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1002/jrsm.1608" } }, { "@type": "ScholarlyArticle", "name": "Treatments for alopecia areata: a network meta-analysis.", "datePublished": "2023-10-23", "url": "https://questionsmedicales.fr/article/37870096", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1002/14651858.CD013719.pub2" } } ], "breadcrumb": { "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "questionsmedicales.fr", "item": "https://questionsmedicales.fr" }, { "@type": "ListItem", "position": 2, "name": "Acides aminés, peptides et protéines", "item": "https://questionsmedicales.fr/mesh/D000602" }, { "@type": "ListItem", "position": 3, "name": "Protéines", "item": "https://questionsmedicales.fr/mesh/D011506" }, { "@type": "ListItem", "position": 4, "name": "Protéines mitochondriales", "item": "https://questionsmedicales.fr/mesh/D024101" } ] } }, { "@type": "MedicalWebPage", "name": "Article complet : Protéines mitochondriales - Questions et réponses", "headline": "Questions et réponses médicales fréquentes sur Protéines mitochondriales", "description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.", "datePublished": "2025-05-05", "inLanguage": "fr", "hasPart": [ { "@type": "MedicalWebPage", "name": "Diagnostic", "headline": "Diagnostic sur Protéines mitochondriales", "description": "Comment diagnostiquer une dysfonction mitochondriale ?\nQuels tests sanguins sont utilisés pour évaluer les protéines mitochondriales ?\nQuels symptômes indiquent une maladie mitochondriale ?\nLes tests génétiques sont-ils fiables pour les maladies mitochondriales ?\nQuel rôle joue l'imagerie dans le diagnostic mitochondrial ?", "url": "https://questionsmedicales.fr/mesh/D024101?mesh_terms=Network+Meta-Analysis#section-diagnostic" }, { "@type": "MedicalWebPage", "name": "Symptômes", "headline": "Symptômes sur Protéines mitochondriales", "description": "Quels sont les symptômes courants des maladies mitochondriales ?\nLes troubles cognitifs sont-ils liés aux protéines mitochondriales ?\nComment la myopathie mitochondriale se manifeste-t-elle ?\nLes troubles cardiaques sont-ils fréquents dans les maladies mitochondriales ?\nLes symptômes varient-ils selon l'âge d'apparition ?", "url": "https://questionsmedicales.fr/mesh/D024101?mesh_terms=Network+Meta-Analysis#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Protéines mitochondriales", "description": "Peut-on prévenir les maladies mitochondriales ?\nL'exercice physique peut-il réduire les risques ?\nLes antioxydants jouent-ils un rôle préventif ?\nUne alimentation équilibrée est-elle importante ?\nLes dépistages précoces sont-ils recommandés ?", "url": "https://questionsmedicales.fr/mesh/D024101?mesh_terms=Network+Meta-Analysis#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Protéines mitochondriales", "description": "Quels traitements sont disponibles pour les maladies mitochondriales ?\nLes coenzymes Q10 sont-elles bénéfiques ?\nLa thérapie génique est-elle une option pour ces maladies ?\nLes régimes alimentaires peuvent-ils aider ?\nLes traitements varient-ils selon le type de maladie mitochondriale ?", "url": "https://questionsmedicales.fr/mesh/D024101?mesh_terms=Network+Meta-Analysis#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Protéines mitochondriales", "description": "Quelles complications peuvent survenir avec les maladies mitochondriales ?\nLes maladies mitochondriales peuvent-elles affecter la fertilité ?\nLes complications peuvent-elles être gérées ?\nLes maladies mitochondriales augmentent-elles le risque de cancer ?\nLes complications cardiovasculaires sont-elles fréquentes ?", "url": "https://questionsmedicales.fr/mesh/D024101?mesh_terms=Network+Meta-Analysis#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Protéines mitochondriales", "description": "Quels sont les facteurs de risque pour les maladies mitochondriales ?\nL'âge est-il un facteur de risque ?\nLes facteurs environnementaux influencent-ils les maladies mitochondriales ?\nLe stress oxydatif est-il un facteur de risque ?\nLes habitudes alimentaires peuvent-elles influencer le risque ?", "url": "https://questionsmedicales.fr/mesh/D024101?mesh_terms=Network+Meta-Analysis#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment diagnostiquer une dysfonction mitochondriale ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "Un diagnostic peut inclure des tests génétiques, des biopsies musculaires et des analyses biochimiques." } }, { "@type": "Question", "name": "Quels tests sanguins sont utilisés pour évaluer les protéines mitochondriales ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Des tests de lactate, pyruvate et des enzymes spécifiques peuvent être effectués." } }, { "@type": "Question", "name": "Quels symptômes indiquent une maladie mitochondriale ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Fatigue, faiblesse musculaire, troubles neurologiques et problèmes cardiaques peuvent indiquer une maladie." } }, { "@type": "Question", "name": "Les tests génétiques sont-ils fiables pour les maladies mitochondriales ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les tests génétiques peuvent identifier des mutations spécifiques liées aux maladies mitochondriales." } }, { "@type": "Question", "name": "Quel rôle joue l'imagerie dans le diagnostic mitochondrial ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "L'imagerie par résonance magnétique (IRM) peut aider à visualiser des anomalies cérébrales." } }, { "@type": "Question", "name": "Quels sont les symptômes courants des maladies mitochondriales ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Les symptômes incluent fatigue, douleurs musculaires, troubles de la vision et épilepsie." } }, { "@type": "Question", "name": "Les troubles cognitifs sont-ils liés aux protéines mitochondriales ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des troubles cognitifs peuvent survenir en raison de dysfonctionnements mitochondriaux." } }, { "@type": "Question", "name": "Comment la myopathie mitochondriale se manifeste-t-elle ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Elle se manifeste par une faiblesse musculaire, des crampes et une intolérance à l'exercice." } }, { "@type": "Question", "name": "Les troubles cardiaques sont-ils fréquents dans les maladies mitochondriales ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des cardiomyopathies peuvent se développer en raison de dysfonctionnements mitochondriaux." } }, { "@type": "Question", "name": "Les symptômes varient-ils selon l'âge d'apparition ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les symptômes peuvent varier considérablement selon l'âge d'apparition de la maladie." } }, { "@type": "Question", "name": "Peut-on prévenir les maladies mitochondriales ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "Certaines maladies génétiques ne peuvent pas être prévenues, mais un mode de vie sain aide." } }, { "@type": "Question", "name": "L'exercice physique peut-il réduire les risques ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Oui, l'exercice régulier peut améliorer la santé mitochondriale et réduire les risques." } }, { "@type": "Question", "name": "Les antioxydants jouent-ils un rôle préventif ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les antioxydants peuvent protéger les mitochondries des dommages oxydatifs." } }, { "@type": "Question", "name": "Une alimentation équilibrée est-elle importante ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Oui, une alimentation riche en nutriments soutient la santé mitochondriale." } }, { "@type": "Question", "name": "Les dépistages précoces sont-ils recommandés ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Oui, le dépistage précoce peut aider à identifier les risques et à intervenir rapidement." } }, { "@type": "Question", "name": "Quels traitements sont disponibles pour les maladies mitochondriales ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Les traitements incluent des suppléments, des thérapies symptomatiques et des approches nutritionnelles." } }, { "@type": "Question", "name": "Les coenzymes Q10 sont-elles bénéfiques ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "Oui, le coenzyme Q10 peut améliorer la fonction mitochondriale et réduire les symptômes." } }, { "@type": "Question", "name": "La thérapie génique est-elle une option pour ces maladies ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "La thérapie génique est en recherche, mais elle pourrait offrir des solutions futures." } }, { "@type": "Question", "name": "Les régimes alimentaires peuvent-ils aider ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des régimes spécifiques peuvent soutenir la fonction mitochondriale et améliorer les symptômes." } }, { "@type": "Question", "name": "Les traitements varient-ils selon le type de maladie mitochondriale ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les traitements doivent être adaptés au type spécifique de maladie mitochondriale." } }, { "@type": "Question", "name": "Quelles complications peuvent survenir avec les maladies mitochondriales ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Les complications incluent des troubles neurologiques, cardiaques et endocriniens." } }, { "@type": "Question", "name": "Les maladies mitochondriales peuvent-elles affecter la fertilité ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certaines maladies mitochondriales peuvent entraîner des problèmes de fertilité." } }, { "@type": "Question", "name": "Les complications peuvent-elles être gérées ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "Certaines complications peuvent être gérées avec des traitements symptomatiques appropriés." } }, { "@type": "Question", "name": "Les maladies mitochondriales augmentent-elles le risque de cancer ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Certaines études suggèrent un lien entre dysfonction mitochondriale et risque accru de cancer." } }, { "@type": "Question", "name": "Les complications cardiovasculaires sont-elles fréquentes ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les maladies mitochondriales peuvent entraîner des cardiomyopathies et d'autres complications." } }, { "@type": "Question", "name": "Quels sont les facteurs de risque pour les maladies mitochondriales ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "Les facteurs incluent des antécédents familiaux, des mutations génétiques et des expositions environnementales." } }, { "@type": "Question", "name": "L'âge est-il un facteur de risque ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certaines maladies mitochondriales se manifestent plus fréquemment avec l'âge." } }, { "@type": "Question", "name": "Les facteurs environnementaux influencent-ils les maladies mitochondriales ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "Oui, l'exposition à des toxines peut augmenter le risque de dysfonction mitochondriale." } }, { "@type": "Question", "name": "Le stress oxydatif est-il un facteur de risque ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Oui, le stress oxydatif peut endommager les mitochondries et contribuer à des maladies." } }, { "@type": "Question", "name": "Les habitudes alimentaires peuvent-elles influencer le risque ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "Oui, une alimentation pauvre en nutriments peut augmenter le risque de dysfonction mitochondriale." } } ] } ] }
Dr Olivier Menir

Contenu validé par Dr Olivier Menir

Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale

Validation scientifique effectuée le 07/04/2025

Contenu vérifié selon les dernières recommandations médicales

En savoir plus sur Dr Menir

Sous-catégories

25 au total
└─

Aldehyde dehydrogenase, mitochondrial

Aldehyde Dehydrogenase, Mitochondrial D000071396 - D12.776.575.093
└─

Mitochondrial creatine kinase

Creatine Kinase, Mitochondrial Form D052281 - D12.776.575.186
└─

DNA Polymerase gamma

DNA Polymerase gamma D000074002 - D12.776.575.280
└─

Ferrochelatase

Ferrochelatase D005294 - D12.776.575.562
└─

Protéines de transport de la membrane mitochondriale

Mitochondrial Membrane Transport Proteins D033681 - D12.776.575.750
└─

Protéine trifonctionnelle mitochondriale

Mitochondrial Trifunctional Protein D063991 - D12.776.575.765
└─

Nucleoside diphosphate kinase D

Nucleoside Diphosphate Kinase D D061107 - D12.776.575.781
└─

Peroxiredoxin III

Peroxiredoxin III D061105 - D12.776.575.812
└─

Prohibitines

Prohibitins D000091402 - D12.776.575.844
└─

Sirtuine-3

Sirtuin 3 D056566 - D12.776.575.875
└─└─

Mitochondrial ADP, ATP Translocases

Mitochondrial ADP, ATP Translocases D000226 - D12.776.575.750.500
└─└─

Pore de transition de perméabilité mitochondriale

Mitochondrial Permeability Transition Pore D000083162 - D12.776.575.750.563
└─└─

Protéines du complexe d'import des protéines précurseurs mitochondriales

Mitochondrial Precursor Protein Import Complex Proteins D000090622 - D12.776.575.750.594
└─└─

Mitochondrial Proton-Translocating ATPases

Mitochondrial Proton-Translocating ATPases D025261 - D12.776.575.750.625
└─└─

Protéines de découplage mitochondrial

Mitochondrial Uncoupling Proteins D000071245 - D12.776.575.750.688
└─└─

Canal anionique-1 voltage-dépendant

Voltage-Dependent Anion Channel 1 D050995 - D12.776.575.750.750
└─└─

Canal anionique-2 voltage-dépendant

Voltage-Dependent Anion Channel 2 D050996 - D12.776.575.750.875
└─└─

Sous-unité alpha de la protéine trifonctionnelle mitochondriale

Mitochondrial Trifunctional Protein, alpha Subunit D063992 - D12.776.575.765.200
└─└─

Sous-unité bêta de la protéine trifonctionnelle mitochondriale

Mitochondrial Trifunctional Protein, beta Subunit D063993 - D12.776.575.765.500
└─└─└─

Translocateur-1 de nucléotides adényliques

Adenine Nucleotide Translocator 1 D033741 - D12.776.575.750.500.100
└─└─└─

Translocateur-2 de nucléotides adényliques

Adenine Nucleotide Translocator 2 D033742 - D12.776.575.750.500.200
└─└─└─

Translocateur-3 de nucléotides adényliques

Adenine Nucleotide Translocator 3 D033781 - D12.776.575.750.500.300
└─└─└─

Protéine-1 de découplage

Uncoupling Protein 1 D000071256 - D12.776.575.750.688.500
└─└─└─

Protéine-2 de découplage

Uncoupling Protein 2 D000071246 - D12.776.575.750.688.750
└─└─└─

Protéine-3 de découplage

Uncoupling Protein 3 D000071247 - D12.776.575.750.688.875

Auteurs principaux

Thomas Becker

3 publications dans cette catégorie

Affiliations :
  • Institute of Biochemistry und Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, 79104 Freiburg, Germany.
  • CIBSS Centre for Integrative Biological Signalling Studies, University of Freiburg, 79104 Freiburg, Germany.
Publications dans "Protéines mitochondriales" :

Johannes M Herrmann

3 publications dans cette catégorie

Affiliations :
  • Cell Biology, University of Kaiserslautern, Kaiserslautern, Germany. Electronic address: hannes.herrmann@biologie.uni-kl.de.
Publications dans "Protéines mitochondriales" :

Timothy E Shutt

2 publications dans cette catégorie

Affiliations :
  • Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada.
  • Alberta Children's Hospital Research Institute, University of Calgary, Calgary, AB T2N 4N1, Canada.
  • Department of Medical Genetics, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada.
  • Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada.
Publications dans "Protéines mitochondriales" :

Cole M Haynes

2 publications dans cette catégorie

Affiliations :
  • Molecular, Cell and Cancer Biology, UMass-Chan Medical School, Worcester, MA 01655, USA.
Publications dans "Protéines mitochondriales" :

Yang Yang

2 publications dans cette catégorie

Affiliations :
  • Stem Cells and Metabolism Research Program, Research Programs Unit, Faculty of Medicine, University of Helsinki, 00014 Helsinki, Finland.
  • School of Life and Health Sciences, Faculty of Science, The Chinese University of Hong Kong, 518172 Shenzhen, China.
Publications dans "Protéines mitochondriales" :

Yury S Bykov

2 publications dans cette catégorie

Affiliations :
  • Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Publications dans "Protéines mitochondriales" :

Maya Schuldiner

2 publications dans cette catégorie

Affiliations :
  • Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel. Electronic address: maya.schuldiner@weizmann.ac.il.
Publications dans "Protéines mitochondriales" :

Süleyman Bozkurt

2 publications dans cette catégorie

Affiliations :
  • Institute of Molecular Systems Medicine, Faculty of Medicine, Goethe University, Frankfurt am Main, Germany.
Publications dans "Protéines mitochondriales" :

Christian Münch

2 publications dans cette catégorie

Affiliations :
  • Institute of Molecular Systems Medicine, Faculty of Medicine, Goethe University, Frankfurt am Main, Germany; Cardio-Pulmonary Institute, Frankfurt am Main, Germany. Electronic address: ch.muench@em.uni-frankfurt.de.
Publications dans "Protéines mitochondriales" :

Bettina Warscheid

2 publications dans cette catégorie

Affiliations :
  • Institute of Biology II, Biochemistry and Functional Proteomics, Faculty of Biology, University of Freiburg, Freiburg, Germany.
  • Signalling Research Centres BIOSS and CIBSS, University of Freiburg, Freiburg, Germany.
Publications dans "Protéines mitochondriales" :

Sarah Gerlich

2 publications dans cette catégorie

Affiliations :
  • Institute of Molecular Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, University Avenue, Glasgow, G12 8QQ Scotland, UK.
  • Department for Chemistry, Institute for Biochemistry, University of Cologne, 50674 Cologne, Germany.
Publications dans "Protéines mitochondriales" :

Markus Räschle

2 publications dans cette catégorie

Affiliations :
  • Molecular Genetics, University of Kaiserslautern, 67663 Kaiserslautern, Germany.
Publications dans "Protéines mitochondriales" :

Nikolaus Pfanner

2 publications dans cette catégorie

Affiliations :
  • Institute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, 79104 Freiburg, Germany; CIBSS Centre for Integrative Biological Signalling Studies, University of Freiburg, 79104 Freiburg, Germany; BIOSS Centre for Biological Signalling Studies, University of Freiburg, 79104 Freiburg, Germany. Electronic address: nikolaus.pfanner@biochemie.uni-freiburg.de.
Publications dans "Protéines mitochondriales" :

Nils Wiedemann

2 publications dans cette catégorie

Affiliations :
  • Institute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, 79104 Freiburg, Germany; CIBSS Centre for Integrative Biological Signalling Studies, University of Freiburg, 79104 Freiburg, Germany; BIOSS Centre for Biological Signalling Studies, University of Freiburg, 79104 Freiburg, Germany. Electronic address: nils.wiedemann@biochemie.uni-freiburg.de.
Publications dans "Protéines mitochondriales" :

Sahebgowda Sidramagowda Patil

1 publication dans cette catégorie

Affiliations :
  • University of South Florida, Division of Allergy and Immunology, Department of Internal Medicine, College of Medicine, Tampa, FL, United States.
Publications dans "Protéines mitochondriales" :

Ramani Soundararajan

1 publication dans cette catégorie

Affiliations :
  • University of South Florida, Division of Allergy and Immunology, Department of Internal Medicine, College of Medicine, Tampa, FL, United States.
Publications dans "Protéines mitochondriales" :

Jutaro Fukumoto

1 publication dans cette catégorie

Affiliations :
  • University of South Florida, Division of Allergy and Immunology, Department of Internal Medicine, College of Medicine, Tampa, FL, United States.
Publications dans "Protéines mitochondriales" :

Mason Breitzig

1 publication dans cette catégorie

Affiliations :
  • University of South Florida, Division of Allergy and Immunology, Department of Internal Medicine, College of Medicine, Tampa, FL, United States.
  • Washington University in St. Louis, Brown School, St. Louis, MO, United States.
Publications dans "Protéines mitochondriales" :

Helena Hernández-Cuervo

1 publication dans cette catégorie

Affiliations :
  • University of South Florida, Division of Allergy and Immunology, Department of Internal Medicine, College of Medicine, Tampa, FL, United States.
  • University of South Florida, Department of Molecular Medicine, College of Medicine, Tampa, FL, United States.
Publications dans "Protéines mitochondriales" :

Matthew Alleyn

1 publication dans cette catégorie

Affiliations :
  • University of South Florida, Division of Allergy and Immunology, Department of Internal Medicine, College of Medicine, Tampa, FL, United States.
Publications dans "Protéines mitochondriales" :

Sources (10000 au total)

Effects of non-pharmacological interventions for adults with subjective cognitive decline: a network meta-analysis and component network meta-analysis.

27 Jun 2024
DOI: 10.1186/s12916-024-03491-z PMID: 38937777

Non-pharmacological interventions have a myriad of available intervention options and contain multiple components. Whether specific components of non-pharmacological interventions or combinations are ... PubMed, Embase, Cochrane, CINAHL, PsycINFO, CENTRAL, Web of Science, and China's two largest databases, CNKI and Wanfang, were searched from inception to 22nd, January 2023. Randomized controlled tria... A total of 39 trials with 2959 patients were included (range of mean ages, 58.79-77.41 years). Resistance exercise might be the optimal intervention for reducing memory complaints in adults with subje... The form of physical activity performed appears to be more beneficial than cognitive interventions in reducing subjective memory complaints for adults with subjective cognitive decline, and this diffe... PROSPERO registry number. CRD42022355363....

Humans Cognitive Dysfunction Network Meta-Analysis Middle Aged Aged +2 autres

Treatments for alopecia areata: a network meta-analysis.

23 10 2023
DOI: 10.1002/14651858.CD013719.pub2 PMID: 37870096

Alopecia areata is an autoimmune disease leading to nonscarring hair loss on the scalp or body. There are different treatments including immunosuppressants, hair growth stimulants, and contact immunot... To assess the benefits and harms of the treatments for alopecia areata (AA), alopecia totalis (AT), and alopecia universalis (AU) in children and adults.... The Cochrane Skin Specialised Register, CENTRAL, MEDLINE, Embase, ClinicalTrials.gov and WHO ICTRP were searched up to July 2022.... We included randomised controlled trials (RCTs) that evaluated classical immunosuppressants, biologics, small molecule inhibitors, contact immunotherapy, hair growth stimulants, and other therapies in... We used the standard procedures expected by Cochrane including assessment of risks of bias using RoB2 and the certainty of the evidence using GRADE. The primary outcomes were short-term hair regrowth ... We included 63 studies that tested 47 different treatments in 4817 randomised participants. All trials used a parallel-group design except one that used a cross-over design. The mean sample size was 7... We found that treatment with baricitinib results in an increase in short- and long-term hair regrowth compared to placebo. Although we found inconclusive results for the risk of serious adverse effect...

Adult Humans Child Child, Preschool Adolescent +11 autres

Does type of funding affect reporting in network meta-analysis? A scoping review of network meta-analyses.

06 05 2023
DOI: 10.1186/s13643-023-02235-z PMID: 37149700

Evidence has shown that private industry-sponsored randomized controlled trials (RCTs) and meta-analyses are more likely to report intervention-favourable results compared with other sources of fundin... To (a) explore the recommendation rate of industry-sponsored NMAs on their company's intervention, and (b) assess reporting in NMAs of pharmacologic interventions according to their funding type.... Design: Scoping review of published NMAs with RCTs.... We used a pre-existing NMA database including 1,144 articles from MEDLINE, EMBASE and Cochrane Database of Systematic Reviews, published between January 2013 and July 2018.... NMAs with transparent funding information and comparing pharmacologic interventions with/without placebo.... We captured whether NMAs recommended their own or another company's intervention, classified NMAs according to their primary outcome findings (i.e., statistical significance and direction of effect), ... We retrieved 658 NMAs, which reported a median of 23 items in the PRISMA-NMA checklist (interquartile range [IQR]: 21-26). NMAs were categorized as 314 publicly-sponsored (PRISMA-NMA median 24.5, IQR ... Differences in completeness of reporting and author characteristics were apparent among NMAs with different types of funding. Publicly-sponsored NMAs had the best reporting and published their finding...

Humans Network Meta-Analysis Bias Checklist MEDLINE +1 autres

Efficacy of innovative therapies in myasthenia gravis: A systematic review, meta-analysis and network meta-analysis.

12 2023
DOI: 10.1111/ene.15872 PMID: 37204031

Therapy for myasthenia gravis (MG) is undergoing a profound change, with new treatments being tested. These include complement inhibitors and neonatal Fc receptor (FcRn) blockers. The aim of this stud... We assessed statistical heterogeneity across trials based on the Cochrane Q test and I... We observed an overall mean Myasthenia Gravis-Activities of Daily Living scale (MG-ADL) score change of -2.17 points (95% confidence interval [CI] -2.67, -1.67; p < 0.001) as compared to placebo. No s... Anti-complement and FcRn treatments both proved to be effective in MG patients, whereas rituximab did not show a significant benefit for patients. Within the limitations of this meta-analysis, includi...

Infant, Newborn Humans Rituximab Network Meta-Analysis Activities of Daily Living +3 autres

Effectiveness of aerobic exercise in the prevention and treatment of postpartum depression: Meta-analysis and network meta-analysis.

2023
DOI: 10.1371/journal.pone.0287650 PMID: 38019729

Aerobic exercise is widely recognized for improving mental health and reducing negative emotions, including anxiety. However, research on its role in preventing and treating postpartum depression (PPD... We conducted a quantitative systematic review of the study in 5 representative databases for the effect of aerobic exercise on PPD. Meta-analysis and network meta-analysis were performed with Review-M... Twenty-six studies with 2,867 participants were eventually included and the efficacy of aerobic exercise in preventing and treating postpartum depression is significant compared to standard care. (MD ... The efficacy of aerobic exercise in preventing and treating postpartum depression is significant compared to standard care, with a greater emphasis on prevention. The optimal prescribed exercise volum...

Female Humans Depression, Postpartum Network Meta-Analysis Exercise +1 autres

Antibiotic Prophylaxis in Reduction Mammaplasty: A Network Meta-Analysis.

06 2023
DOI: 10.1007/s00266-023-03313-2 PMID: 36928312

Mounting evidence suggests that breast reduction surgery displays higher rates of surgical site infections (SSI) than initially presumed. Objective of this network meta-analysis is to evaluate the eff... A network meta-analysis was conducted using a predetermined protocol after searching the electronic databases MEDLINE, Scopus, the Cochrane Library and US National Institutes of Health Ongoing Trials ... A total of 10 studies was included in the analysis involving 1331 patients. All but one study controlled for major risk factors, and no differences were observed in patients' baseline characteristics.... Antibiotics mitigate the SSI rate after breast reduction. This meta-analysis provides an evidence-based strategy to optimize antibiotic administration. Further research is needed though to examine ant... This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Inst...

Female Humans Surgical Wound Infection Antibiotic Prophylaxis Network Meta-Analysis +2 autres