questionsmedicales.fr
Composés chimiques organiques
Lactones
Épothilones
Épothilones : Questions médicales fréquentes
Diagnostic
2
Épothilones
Cancer
Diagnostic
Épothilones
Imagerie médicale
Analyse sanguine
Symptômes
2
Épothilones
Effets secondaires
Nausées
Épothilones
Douleurs musculaires
Troubles gastro-intestinaux
Prévention
2
Épothilones
Prévention des effets secondaires
Médicaments antiémétiques
Épothilones
Évaluation médicale
Prévention
Traitements
2
Épothilones
Administration intraveineuse
Traitement du cancer
Épothilones
Chimiothérapie
Traitement combiné
Complications
2
Épothilones
Complications
Thrombocytopénie
Épothilones
Gestion des complications
Transfusions sanguines
Facteurs de risque
2
Épothilones
Facteurs de risque
Maladies cardiaques
Épothilones
Sécurité du traitement
Évaluation de la santé
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Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 23/03/2026
Contenu vérifié selon les dernières recommandations médicales
5 publications dans cette catégorie
Affiliations :
State Key Laboratory of Microbial Technology, Institute of Microbial Technology, Shandong University, Qingdao, 266237, China.
Publications dans "Épothilones" :
3 publications dans cette catégorie
Affiliations :
Active Carbohydrate Research Institute, Chongqing Key Laboratory of Green Synthesis and Application, College of Chemistry, Chongqing Normal University, Chongqing, China.
Publications dans "Épothilones" :
3 publications dans cette catégorie
Affiliations :
Collaborative Innovation Center for Genetics and Development, State Key Laboratory of Genetic Engineering, Department of Microbiology, School of Life Sciences, Fudan University, Shanghai, 200438, People's Republic of China.
Publications dans "Épothilones" :
3 publications dans cette catégorie
Affiliations :
Collaborative Innovation Center for Genetics and Development, State Key Laboratory of Genetic Engineering, Department of Microbiology, School of Life Sciences, Fudan University, Shanghai, 200438, People's Republic of China.
Publications dans "Épothilones" :
3 publications dans cette catégorie
Affiliations :
Shandong University-Helmholtz Institute of Biotechnology, State Key Laboratory of Microbial Technology, School of Life Sciences, Shandong University, Qingdao, Shandong 266237, People's Republic of China.
Publications dans "Épothilones" :
3 publications dans cette catégorie
Affiliations :
Shandong University-Helmholtz Institute of Biotechnology, State Key Laboratory of Microbial Technology, School of Life Sciences, Shandong University, Qingdao, Shandong 266237, People's Republic of China.
Publications dans "Épothilones" :
3 publications dans cette catégorie
Affiliations :
Collaborative Innovation Center for Genetics and Development, State Key Laboratory of Genetic Engineering, Department of Microbiology, School of Life Sciences, Fudan University, Shanghai, 200438, People's Republic of China.
Publications dans "Épothilones" :
3 publications dans cette catégorie
Affiliations :
Enzymology and Fungal Biotechnology Lab, Botany and Microbiology Department, Faculty of Science, Zagazig University, Zagazig, 44519, Egypt. Electronic address: ash.elsayed@gmail.com.
Publications dans "Épothilones" :
2 publications dans cette catégorie
Affiliations :
Active Carbohydrate Research Institute, Chongqing Key Laboratory of Green Synthesis and Application, College of Chemistry, Chongqing Normal University, Chongqing, China.
Publications dans "Épothilones" :
2 publications dans cette catégorie
Affiliations :
Active Carbohydrate Research Institute, Chongqing Key Laboratory of Green Synthesis and Application, College of Chemistry, Chongqing Normal University, Chongqing, China.
Publications dans "Épothilones" :
2 publications dans cette catégorie
Affiliations :
State Key Laboratory of Microbial Technology, Institute of Microbial Technology, Shandong University, Qingdao, 266237, China.
Publications dans "Épothilones" :
2 publications dans cette catégorie
Affiliations :
State Key Laboratory of Microbial Technology, Institute of Microbial Technology, Shandong University, Qingdao, 266237, China.
Publications dans "Épothilones" :
2 publications dans cette catégorie
Affiliations :
State Key Laboratory of Microbial Technology, Institute of Microbial Technology, Shandong University, Qingdao, 266237, China.
Publications dans "Épothilones" :
2 publications dans cette catégorie
Affiliations :
State Key Laboratory of Microbial Technology, Institute of Microbial Technology, Shandong University, Qingdao, 266237, China.
Publications dans "Épothilones" :
2 publications dans cette catégorie
Affiliations :
Collaborative Innovation Center for Genetics and Development, State Key Laboratory of Genetic Engineering, Shanghai Engineering Research Center of Industrial Microorganisms, Department of Microbiology, School of Life Sciences, Fudan University, Shanghai, 200438, People's Republic of China.
CAS Key Laboratory of Synthetic Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, 200032, People's Republic of China.
Publications dans "Épothilones" :
2 publications dans cette catégorie
Affiliations :
Utrecht University, Department of Biology, NETHERLANDS.
Publications dans "Épothilones" :
2 publications dans cette catégorie
Affiliations :
Ludwig-Maximilians-Universitat Munchen, Dept Pharmacy, Butenandtstr 5-13, 81377, Munich, GERMANY.
Publications dans "Épothilones" :
2 publications dans cette catégorie
Affiliations :
Laboratory for Axonal Growth and Regeneration, German Center for Neurodegenerative Diseases (DZNE), Bonn 53127, Germany.
Publications dans "Épothilones" :
2 publications dans cette catégorie
Affiliations :
Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia.
Publications dans "Épothilones" :
2 publications dans cette catégorie
Affiliations :
School of Chemistry and Chemical Engineering, Frontiers Science Center for Transformative Molecules, Shanghai Jiao Tong University, Shanghai 200240, China.
Publications dans "Épothilones" :
Taxane-induced peripheral neurotoxicity (TIPN) is the most common non-hematological side effect of taxane-based chemotherapy, and may result in dose reductions and discontinuations, having as such a d...
Epothilones are one of the common prescribed anticancer drugs for solid tumors, for their exceptional binding affinity with β-tubulin microtubule, stabilizing their disassembly, causing an ultimate ar...
Chemotherapy-induced peripheral neuropathy is a common adverse reaction in a variety of medications frequently used for a great number of cancer treatments. This condition consists of mainly sensory-t...
To determine the prevalence of chemotherapy-induced peripheral neuropathy in a Colombian population....
A real-world evidence cross-sectional retrospective study was performed in all patients from oncological clinical centers in Colombia, which received pharmacological therapy for any cancer between Jan...
A total of 1,551 patients in four cities were included, and 11,280 doses were applied; predominantly females (n = 1,094; 70.5%), with a mean age of 57 ± 13 years old. Paclitaxel was the most commonly ...
Chemotherapy-induced peripheral neuropathy is a frequent adverse reaction to daily cancer therapy in Colombian patients managed with taxanes, alkylators, proteasome inhibitors, and epothilone B analog...
Epothilone is a natural 16-membered macrolide cytotoxic compound produced by the metabolism of the cellulose-degrading myxobacterium...
Epothilone B (Epo B) is a potent antitumor natural product with sub-nanomolar anti-proliferation action against several human cancer cells. However, poor selectivity to tumor cells and unacceptable th...
Central nervous system injury, specifically traumatic brain and spinal cord injury, can have significant long lasting effects. There are no comprehensive treatments to combat the injury and sequalae o...
Epothilones are a kind of 16-member macrolides with strong anticancer activity, which was produced by Sorangium cellulosum. Epothlione D shows better drug resistance and safety than taxol in clinical ...
Glycosyltransferases typically display acceptor substrate flexibility but more stringent donor specificity. BsGT-1 is a highly effective glycosyltransferase to glycosylate macrolides, including epothi...
Optical methods to modulate microtubule dynamics show promise for reaching the micron- and millisecond-scale resolution needed to decrypt the roles of the cytoskeleton in biology. However, optical mic...
Epothilones are 16-membered macrolides that can act as microtubule-targeting agents to tackle cancer. Many synthetic analogues have been investigated for their activity, yet often based on macrolide s...