questionsmedicales.fr
Acides aminés, peptides et protéines
Protéines
Protéines inhibitrices de la fraction C1 du complément
C1 Inhibiteur
C1 Inhibiteur : Questions médicales fréquentes
Termes MeSH sélectionnés :
Multidetector Computed Tomography
Diagnostic
5
Déficience en C1 inhibiteur
Tests de laboratoire
Protéines du complément
Tests de laboratoire
Antécédents médicaux
Hérédité
Symptômes
5
Maladies auto-immunes
Allergies
Prévention
5
Allergies alimentaires
Réactions
Stress
Facteurs déclenchants
Traitements
5
Traitement
Médicaments anti-inflammatoires
Corticostéroïdes
Inflammation
Thérapie génique
Traitements expérimentaux
Crise aiguë
Administration de médicaments
Complications
5
Œdème laryngé
Difficultés respiratoires
Maladies auto-immunes
Risque accru
Qualité de vie
Symptômes chroniques
Surveillance médicale
Complications
Facteurs de risque
5
Facteurs de risque
Hérédité
Facteurs environnementaux
Crises
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"@type": "Question",
"name": "Comment diagnostiquer une déficience en C1 inhibiteur ?",
"position": 1,
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"text": "Un dosage sanguin du C1 inhibiteur et des tests fonctionnels sont nécessaires."
}
},
{
"@type": "Question",
"name": "Quels tests sont utilisés pour évaluer le C1 inhibiteur ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les tests incluent le dosage du C1 inhibiteur et l'évaluation de l'activité fonctionnelle."
}
},
{
"@type": "Question",
"name": "Quels symptômes indiquent un problème de C1 inhibiteur ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes incluent des œdèmes, des douleurs abdominales et des éruptions cutanées."
}
},
{
"@type": "Question",
"name": "Le diagnostic nécessite-t-il une consultation spécialisée ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une consultation en immunologie ou en allergologie est souvent recommandée."
}
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{
"@type": "Question",
"name": "Peut-on diagnostiquer par des antécédents familiaux ?",
"position": 5,
"acceptedAnswer": {
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"text": "Oui, des antécédents familiaux de symptômes similaires peuvent orienter le diagnostic."
}
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{
"@type": "Question",
"name": "Quels sont les symptômes d'une carence en C1 inhibiteur ?",
"position": 6,
"acceptedAnswer": {
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"text": "Les symptômes incluent des œdèmes récurrents, des douleurs abdominales et des éruptions cutanées."
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"@type": "Question",
"name": "Les symptômes varient-ils selon l'âge ?",
"position": 7,
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}
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"@type": "Question",
"name": "Les œdèmes sont-ils toujours présents ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Non, les œdèmes peuvent être intermittents et ne pas se manifester constamment."
}
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"@type": "Question",
"name": "Y a-t-il des symptômes associés à des infections ?",
"position": 9,
"acceptedAnswer": {
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"text": "Oui, des infections peuvent exacerber les symptômes liés à la carence en C1 inhibiteur."
}
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{
"@type": "Question",
"name": "Les symptômes peuvent-ils être confondus avec d'autres maladies ?",
"position": 10,
"acceptedAnswer": {
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"text": "Oui, ils peuvent être similaires à ceux d'autres troubles allergiques ou auto-immuns."
}
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{
"@type": "Question",
"name": "Comment prévenir les crises d'œdème ?",
"position": 11,
"acceptedAnswer": {
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"text": "Éviter les déclencheurs connus et suivre un traitement préventif régulier."
}
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{
"@type": "Question",
"name": "Les patients doivent-ils éviter certains aliments ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certains aliments peuvent déclencher des réactions, il est conseillé de les identifier."
}
},
{
"@type": "Question",
"name": "Le stress influence-t-il les crises ?",
"position": 13,
"acceptedAnswer": {
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"text": "Oui, le stress peut être un facteur déclenchant pour certaines personnes."
}
},
{
"@type": "Question",
"name": "Des vaccinations sont-elles recommandées ?",
"position": 14,
"acceptedAnswer": {
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"text": "Oui, les vaccinations peuvent aider à prévenir les infections qui aggravent les symptômes."
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"@type": "Question",
"name": "Les patients doivent-ils porter un bracelet médical ?",
"position": 15,
"acceptedAnswer": {
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}
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{
"@type": "Question",
"name": "Quels traitements sont disponibles pour la carence en C1 inhibiteur ?",
"position": 16,
"acceptedAnswer": {
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"text": "Les traitements incluent des concentrés de C1 inhibiteur et des médicaments anti-inflammatoires."
}
},
{
"@type": "Question",
"name": "Le traitement préventif est-il nécessaire ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un traitement préventif peut être recommandé pour éviter les crises d'œdème."
}
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{
"@type": "Question",
"name": "Les corticostéroïdes sont-ils efficaces ?",
"position": 18,
"acceptedAnswer": {
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"text": "Les corticostéroïdes peuvent réduire l'inflammation, mais ne traitent pas la cause sous-jacente."
}
},
{
"@type": "Question",
"name": "Y a-t-il des traitements expérimentaux ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des thérapies géniques et des traitements ciblés sont en cours d'évaluation."
}
},
{
"@type": "Question",
"name": "Comment gérer une crise aiguë ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'administration rapide de C1 inhibiteur est essentielle lors d'une crise aiguë."
}
},
{
"@type": "Question",
"name": "Quelles sont les complications possibles de la carence en C1 inhibiteur ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent des œdèmes sévères, des infections et des douleurs chroniques."
}
},
{
"@type": "Question",
"name": "Les œdèmes peuvent-ils entraîner des complications graves ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des œdèmes laryngés peuvent provoquer des difficultés respiratoires potentiellement mortelles."
}
},
{
"@type": "Question",
"name": "Y a-t-il un risque accru de maladies auto-immunes ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les patients peuvent avoir un risque accru de développer des maladies auto-immunes."
}
},
{
"@type": "Question",
"name": "Les complications peuvent-elles affecter la qualité de vie ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les symptômes chroniques et les crises peuvent significativement altérer la qualité de vie."
}
},
{
"@type": "Question",
"name": "Les complications nécessitent-elles une surveillance régulière ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une surveillance régulière est essentielle pour gérer les complications potentielles."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque de carence en C1 inhibiteur ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les antécédents familiaux et certaines mutations génétiques augmentent le risque."
}
},
{
"@type": "Question",
"name": "Les infections fréquentes sont-elles un facteur de risque ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les infections récurrentes peuvent exacerber les symptômes chez les patients."
}
},
{
"@type": "Question",
"name": "Le sexe influence-t-il le risque de carence ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la carence en C1 inhibiteur est plus fréquente chez les femmes que chez les hommes."
}
},
{
"@type": "Question",
"name": "L'âge joue-t-il un rôle dans le risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le risque peut augmenter avec l'âge, bien que les symptômes apparaissent souvent plus tôt."
}
},
{
"@type": "Question",
"name": "Les facteurs environnementaux influencent-ils le risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certains facteurs environnementaux peuvent déclencher des crises chez les individus sensibles."
}
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}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 01/05/2025
Contenu vérifié selon les dernières recommandations médicales
8 publications dans cette catégorie
Affiliations :
Department of Internal Medicine and Haematology, Hungarian Angioedema Center of Reference and Excellence, Semmelweis University, Szentkiralyi u. 46, Budapest, 1088, Hungary. farkas.henriette@med.semmelweis-univ.hu.
4 publications dans cette catégorie
Affiliations :
Department of Internal Medicine and Haematology, Hungarian Angioedema Center of Reference and Excellence, Semmelweis University, Szentkiralyi u. 46, Budapest, 1088, Hungary.
Publications dans "C1 Inhibiteur" :
4 publications dans cette catégorie
Affiliations :
Department of Immunology and Histocompatibility, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece.
CeMIA SA, Larissa, Greece.
Publications dans "C1 Inhibiteur" :
4 publications dans cette catégorie
Affiliations :
Department of Biomedical and Clinical Sciences Luigi Sacco, University of Milan, Via G.B. Grassi 74, 20157 Milan, Italy.
Publications dans "C1 Inhibiteur" :
3 publications dans cette catégorie
Affiliations :
ASST-Fatebenefratelli-Sacco, Milan, Italy. chiarasuffritti@gmail.com.
Publications dans "C1 Inhibiteur" :
3 publications dans cette catégorie
Affiliations :
Department of Immunology and Histocompatibility, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece.
Publications dans "C1 Inhibiteur" :
3 publications dans cette catégorie
Affiliations :
CeMIA SA, Larissa, Greece.
Publications dans "C1 Inhibiteur" :
3 publications dans cette catégorie
Affiliations :
Department of Allergology, Navy Hospital, Athens, Greece.
Publications dans "C1 Inhibiteur" :
3 publications dans cette catégorie
Publications dans "C1 Inhibiteur" :
3 publications dans cette catégorie
Affiliations :
Department of Otorhinolaryngology, Head and Neck Surgery, Ulm University Medical Center, Ulm, Germany.
Publications dans "C1 Inhibiteur" :
3 publications dans cette catégorie
Affiliations :
Department of Otorhinolaryngology, Head and Neck Surgery, Ulm University Medical Center, Ulm, Germany.
Publications dans "C1 Inhibiteur" :
3 publications dans cette catégorie
Affiliations :
Department of Otorhinolaryngology, Head and Neck Surgery, Ulm University Medical Center, Ulm, Germany.
Publications dans "C1 Inhibiteur" :
3 publications dans cette catégorie
Affiliations :
Department of Translational Medicine, University of Naples, Via S. Pansini 5, 80131 Naples, Italy.
Publications dans "C1 Inhibiteur" :
2 publications dans cette catégorie
Affiliations :
Department of Translational Medicine, Division of Medical Protein Chemistry, Lund University, Malmö, Sweden.
Publications dans "C1 Inhibiteur" :
2 publications dans cette catégorie
Affiliations :
Sanquin Diagnostic Services, Amsterdam, The Netherlands.
Publications dans "C1 Inhibiteur" :
2 publications dans cette catégorie
Affiliations :
Department of Immunopathology, Sanquin Research and Landsteiner Laboratory, Amsterdam University Medical Centre, Amsterdam Infection and Immunity Institute, Amsterdam, The Netherlands.
Department of Pediatric Immunology, Rheumatology, and Infectious Diseases, Emma Children's Hospital, Amsterdam University Medical Center, Amsterdam, The Netherlands.
Publications dans "C1 Inhibiteur" :
2 publications dans cette catégorie
Affiliations :
Department of Internal Medicine and Haematology, Hungarian Angioedema Center of Reference and Excellence, Semmelweis University, Szentkiralyi u. 46, Budapest, 1088, Hungary.
Publications dans "C1 Inhibiteur" :
2 publications dans cette catégorie
Affiliations :
Department of Internal Medicine and Haematology, Hungarian Angioedema Center of Reference and Excellence, Semmelweis University, Szentkiralyi u. 46, Budapest, 1088, Hungary.
Publications dans "C1 Inhibiteur" :
2 publications dans cette catégorie
Affiliations :
Department of Internal Medicine and Haematology, Semmelweis University, Budapest, Hungary.
Publications dans "C1 Inhibiteur" :
2 publications dans cette catégorie
Affiliations :
Department of Pediatrics, Eastern Virginia Medical School, 700 West Olney Road, Norfolk, VA 23507, USA.
Children's Specialty Group, 811 Redgate Avenue, Norfolk, VA 23507, USA.
Children's Hospital of the King's Daughters, 601 Children's Lane, Norfolk, VA 23507, USA.
Department of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, 700 West Olney Road, Norfolk, VA 23507-1696, USA.
Publications dans "C1 Inhibiteur" :
Knowledge about anatomical variants of the external carotid artery is crucial in head and neck surgery and interventional technique. This work aimed to present the frequency of regular and another var...
This retrospective study included 120 patients in our university hospital between April 2017 and October 2021. They were 65 men and 55 women (mean age, 45.6 years; range, 18-65 years). They were angio...
According to the level of bifurcation; the external carotid artery originated at the level of the upper border of the thyroid cartilage in 164/240 cases (68.3%), and a higher level was detected in 76/...
MDCT angiography is a valuable noninvasive diagnostic tool for evaluating the external carotid artery and its branches....
The objective of this study was to correlate multidetector computed tomography (MDCT) findings in hepatic alveolar echinococcosis (HAE) with intraoperative and postoperative histopathological results ...
A total of 136 HAE patients who underwent CT examination were included in this study. The lesion-vessel contact angle, irregular wall, lumen stenosis and occlusion were evaluated....
A total of 614 veins were estimated. In total, 510 veins were invaded, and 104 veins were not. The invasion rate was 83.06%. In single CT findings, with a cutoff value of > 180° determined by receiver...
The lesion-vessel contact angle > 180° had the best sensitivity and specificity in the diagnosis of HAE venous invasion, and good interobserver agreement had been noted. The diagnostic performance of ...
Multidetector computed tomography (MDCT) can provide valuable information for mitral assessment, but its role in transcatheter mitral edge-to-edge repair (TEER) planning has been poorly elucidated. We...
The deep femoral artery (DFA) is the largest and thickest branch of the femoral artery (FA), separated from the posterior lateral surface of the FA. This study aimed to analyze the anatomy of DFA usin...
Eight hundred right and left DFA MDCT angiography images from 400 individuals, 302 males (75.5%) and 98 females (24.5%), were included....
It was determined that the DFA originates from six different aspects of the FA. The DFA was found to most commonly originate from the posterolateral aspect of the FA, with an incidence of 53%. The DFA...
Knowledge regarding the anatomical variants and morphology of the DFA will enhance the accuracy of decision-making during interventional procedures and operations in the femoral region, as well as aid...
Forensic pathologists have to deal with post-mortem changes of the human body. Those post-mortem phenomena are familiar and largely described in thanatology. However, knowledge about the influence of ...
We report a case of a 2-day-old male with a diagnosis of interrupted aortic arch combined with aortopulmonary window suspected through echocardiography and confirmed by multidetector computer tomograp...
Childhood interstitial lung disease (chILD) is an umbrella concept covering a wide range of rare lung diseases, many of which are unique to childhood. The diagnosis is based on clinical presentation, ...
We searched the biopsy, MDCT, and clinical information database of a single national paediatric referral hospital for 2004-2020. Data were from affected children under age 18. MDCT images we reanalyse...
We included 90 patients, of whom 63 (70 %) were male. The median age at biopsy was 1.3 years (interquartile range 0.1-16.8). Biopsy findings fell into 26 histological classes covering all nine chILD c...
Among cases of chILD, we identified a specific predefined MDCT pattern in only 43 %. However, when such a recognizable pattern occurred, it was predictive of the final chILD diagnosis....
With aging of the global population peripheral arterial disease is increasingly common. Arteriography, computed tomography angiography and magnetic resonance angiography are common modalities used for...
A prospective cross sectional descriptive study involving 114 patients was conducted from November 2015 to October 2016. The patients were evaluated by Doppler ultrasound following multi-detector comp...
Duplex imaging showed sensitivity 94.94%, specificity 98.54%, accuracy 97.54%, positive predictive value 96.15 % and negative predictive value 98.06 %. In assessment of 22 segments, partial stenosis s...
Duplex imaging is safe cost effective and reliable method of evaluation of patients with peripheral arterial diseases....
The present study sought to evaluate the morphology and associated cardiovascular anomalies in patients with aortopulmonary window on virtual dissection of multidetector computed tomography (CT) angio...
We conducted a retrospective search of our departmental database from January 2014 to September 2021 to identify patients with aortopulmonary window and relevant information was extracted from the ele...
An aortopulmonary window was observed in 26 patients (20 males; 6 females). Based on location of the defect, a distal aortopulmonary window was the most common subtype, seen in 13/26 (50%) patients fo...
Aortopulmonary window is associated with a wide gamut of cardiovascular lesions, with ventricular septal defect being the commonest associated anomaly followed by tetralogy of Fallot and interrupted a...
The evaluation of patients following aortic valve replacement has evolved, with multiple imaging modalities available that complement each other and permit better and prompt delineation of specific st...