questionsmedicales.fr
Phénomènes génétiques
Régulation de l'expression des gènes
Modification traductionnelle des protéines
Maturation post-traductionnelle des protéines
Réponse aux protéines mal repliées
Réponse aux protéines mal repliées : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Réponse aux protéines mal repliées
Stress cellulaire
Biopsie
Analyse protéomique
Imagerie médicale
Complications
Biomarqueurs
Protéines chaperonnes
Antécédents médicaux
Maladies métaboliques
Symptômes
5
Fatigue
Troubles métaboliques
Douleur musculaire
Douleur articulaire
Troubles cognitifs
Céphalée
Métabolisme
Résistance à l'insuline
Nausées
Troubles gastro-intestinaux
Prévention
5
Mode de vie sain
Gestion du stress
Bilan de santé
Prévention
Éducation à la santé
Sensibilisation
Soutien psychologique
Santé mentale
Traitements
5
Thérapies ciblées
Médicaments anti-inflammatoires
Exercice physique
Stress cellulaire
Inhibiteurs de protéase
Médicaments
Thérapie génique
Recherche
Complications
5
Maladies métaboliques
Cancers
Troubles cardiovasculaires
Inflammation
Facteurs de risque
5
Stress oxydatif
Prédispositions génétiques
Vieillissement
Dysfonctionnement
Mode de vie sédentaire
Alimentation
Maladies auto-immunes
Exacerbation
Tabagisme
Stress cellulaire
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"name": "L'UPR affecte-t-elle le métabolisme ?",
"position": 9,
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"name": "Des symptômes digestifs sont-ils possibles ?",
"position": 10,
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"position": 11,
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"text": "Maintenir un mode de vie sain et gérer le stress peut aider à prévenir l'UPR."
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"@type": "Question",
"name": "L'évitement de toxines est-il important ?",
"position": 12,
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"text": "Oui, éviter les toxines environnementales peut réduire le risque d'UPR."
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"@type": "Question",
"name": "Les bilans de santé réguliers sont-ils utiles ?",
"position": 13,
"acceptedAnswer": {
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"position": 14,
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"@type": "Question",
"name": "L'alimentation influence-t-elle l'UPR ?",
"position": 17,
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"text": "Oui, une alimentation riche en antioxydants peut aider à réduire le stress cellulaire."
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"@type": "Question",
"name": "Les exercices physiques sont-ils bénéfiques ?",
"position": 18,
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"text": "Oui, l'exercice modéré peut améliorer la réponse au stress cellulaire."
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"name": "Des médicaments spécifiques sont-ils prescrits ?",
"position": 19,
"acceptedAnswer": {
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"text": "Des médicaments comme les inhibiteurs de la protéase peuvent être utilisés."
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"@type": "Question",
"name": "La thérapie génique est-elle une option ?",
"position": 20,
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"text": "La thérapie génique est en recherche pour corriger des défauts liés à l'UPR."
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"@type": "Question",
"name": "Quelles complications peuvent survenir ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des maladies métaboliques, des troubles neurologiques et des cancers peuvent survenir."
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"@type": "Question",
"name": "L'UPR peut-elle entraîner des maladies chroniques ?",
"position": 22,
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"text": "Oui, l'UPR est liée à des maladies chroniques comme le diabète et l'obésité."
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"@type": "Question",
"name": "Y a-t-il un risque accru de cancer ?",
"position": 23,
"acceptedAnswer": {
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"@type": "Question",
"name": "Des troubles cardiovasculaires sont-ils possibles ?",
"position": 24,
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"@type": "Question",
"name": "L'UPR affecte-t-elle la longévité ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des études suggèrent que l'UPR peut influencer la longévité et la santé globale."
}
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"@type": "Question",
"name": "Quels sont les facteurs de risque de l'UPR ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent le stress oxydatif, l'inflammation et des prédispositions génétiques."
}
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{
"@type": "Question",
"name": "L'âge est-il un facteur de risque ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le vieillissement augmente le risque de dysfonctionnement de l'UPR."
}
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{
"@type": "Question",
"name": "Le mode de vie influence-t-il l'UPR ?",
"position": 28,
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"@type": "Answer",
"text": "Oui, un mode de vie sédentaire et une mauvaise alimentation augmentent le risque."
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{
"@type": "Question",
"name": "Les maladies auto-immunes sont-elles un risque ?",
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"@type": "Question",
"name": "Le tabagisme est-il un facteur de risque ?",
"position": 30,
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Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
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Publications dans "Réponse aux protéines mal repliées" :
Traditional education of clinical training mainly relies on a single mode of lecture-based learning (LBL), in which the teacher lectures and the students listen, and the teaching effect is often unsat...
Through objective evaluation of joint surgery students' theoretical knowledge and clinical skills, and subjective evaluation of teaching quality by anonymous questionnaire, the teaching effects of LBL...
Sixty students who participated in the standardized training of residents in the Center for Joint Surgery, Southwest Hospital, Army University, China from March 2020 to September 2021 were selected an...
The scores of theoretical knowledge, clinical skills and total score of group C were (86.40 ± 9.76), (92.15 ± 4.49), (88.70 ± 5.75) points respectively, which were significantly higher than (78.80 ± 1...
SBL combined with CPBL teaching mode can effectively improve the theoretical knowledge and clinical skills of the students, which could improve self-assessment and teaching satisfaction rate, and is w...
Team-based learning (TBL) and problem-based learning (PBL) are two effective educational approaches used in medical education for increasing knowledge acquisition, learning motivation, and collaborati...
The present study aimed to evaluate the perceptions of current or previous preclinical students at the College of Medicine, Najran University (NU) about the effectiveness of PBL and TBL and to assess ...
A cross-sectional survey was conducted on 106 preclinical students at NU, Saudi Arabia. The survey questionnaire was validated by a pilot study and designed based on Kirkpatrick's evaluation model. De...
73.6% of participants enjoyed PBL and found it motivating compared to TBL and classic lectures. PBL was reported as more effective for knowledge acquisition (50%), teamwork (62.3%), and high academic ...
It is concluded that PBL was more favored by the students regarding the learning outcomes. TBL was reported to need more individual preparation and effort and require lecturer involvement, suggesting ...
To enhance tutors' teaching skills, tutor shadowing for novice tutors of problem-based learning (PBL) in addition to conventional faculty development (FD) was applied. This study aimed to develop a tu...
This study employed a before-and-after study design with three phases. In phase 1, a TS-scale was elaborated. A validity examination was performed in phase 2. Phase 3 was a study of the effectiveness ...
A TS-scale with a 32-item questionnaire of self-rated confidence for PBL tutors was identified in phase 1. In phase 2, 7 experienced specialists in medical education were invited to evaluate the conte...
Novice PBL tutors benefit from FD that incorporates tutor shadowing in the 3 key domains of tutoring competencies. The TS-scale developed in this study can be applied in future research on FD design....
Problem-based learning (PBL) is a learner-centered method in which complex real-world problems are used to stimulate students thinking and problem-solving abilities during the teaching and learning pr...
This study developed a problem-based learning (PBL) module to improve integrated thinking and problem-solving ability in students of dental hygiene. After applying PBL, the study tested the improvemen...
This meta-analysis was conducted to systematically evaluate the impact of problem-based learning (PBL) and lecture-based learning (LBL) teaching models on students' learning in surgical education....
We systematically searched the publications related to the application of PBL and LBL in surgical courses in PubMed, Embase, Web of Science and Cochrane Library databases, the last retrieval time is S...
Nine studies were included totally. The results showed that compared with LBL, PBL was superior in clinical competence (SMD = 0.81, 95% CI: 0.12 ~ 1.49, P = 0.020) and student satisfaction (SMD = 2.13...
This study showed that the PBL teaching model is more effective than the LBL teaching model in surgical education on the aspects of enhancing clinical competence and student satisfaction. However, fur...
To study the application of PBL combined with CBL teaching mode in the teaching of international classification of diseases (ICD) encoding, so as to improve students' grasp of ICD encoding knowledge. ...
With traditional lecture-based learning methods often criticized for their limited ability to foster critical thinking and cognitive engagement, problem-based learning (PBL) has emerged as a promising...
PBL was implemented in an undergraduate public health course at a private university in the southeast US. The study was conducted in the Spring of 2022 using a convergent mixed-methods approach. Quant...
Results indicated significant improvements in student communication skills, growth mindset, and metacognitive abilities across the semester. The thematic analysis of qualitative responses corroborated...
The findings contribute to the growing body of evidence supporting PBL and offer practical insights for implementing PBL in public health education. The study also highlights the need for institutiona...
Problem-based learning (PBL) is a pedagogy involving self-directed learning in small groups around case problems. Group function is important to PBL outcomes, but there is currently poor scaffolding a...
Tool development unfolded in four steps: 1) a literature review was conducted to identify existent evaluation tools for group function in PBL, 2) literature findings informed the development of this n...
Nineteen scales relating to group function assessment were identified in the literature, lending 18 constructs that mapped into four dimensions: Learning Climate, Facilitation and Process, Engagement ...
A four-dimension tool to assist group function reflection in PBL was produced. Its constructs were well supported by literature and experts. Faculty and student stakeholders acknowledged the utility o...
The adaptation process for first-year medical students is an important problem because it significantly affects educational activities. The previous study showed that 63% of students had difficulties ...
We searched PubMed, ScienceDirect, Cochrane, and Google Scholar databases until June 5, 2021. Search terms included problem-based learning, effectiveness, effectivity, and medical student. We excluded...
Seven eligible studies (622 patients) were included. The pooled analysis demonstrated no significant difference between PBL with conventional learning method in critical thinking/knowledge assessment ...
The present study concluded that the PBL approach in first-year medical students appeared to be ineffective in improving critical thinking/knowledge, problem-solving, and self-directed compared with t...
