A bipartite boundary element restricts
Angelman Syndrome
/ genetics
Binding Sites
Chromatin
/ genetics
Epistasis, Genetic
Exons
Gene Expression
Gene Expression Regulation
Genomic Imprinting
Induced Pluripotent Stem Cells
/ cytology
Neurons
/ metabolism
Protein Binding
RNA, Antisense
RNA, Long Noncoding
Sequence Deletion
Ubiquitin-Protein Ligases
/ genetics
Angelman syndrome
antisense transcript
genomic imprinting
iPSC
long noncoding RNA
Journal
Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876
Informations de publication
Date de publication:
05 02 2019
05 02 2019
Historique:
pubmed:
25
1
2019
medline:
17
4
2019
entrez:
25
1
2019
Statut:
ppublish
Résumé
Angelman syndrome (AS) is a severe neurodevelopmental disorder caused by the loss of function from the maternal allele of
Identifiants
pubmed: 30674673
pii: 1815279116
doi: 10.1073/pnas.1815279116
pmc: PMC6369781
doi:
Substances chimiques
Chromatin
0
RNA, Antisense
0
RNA, Long Noncoding
0
UBE3A protein, human
EC 2.3.2.26
Ubiquitin-Protein Ligases
EC 2.3.2.27
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
2181-2186Subventions
Organisme : NICHD NIH HHS
ID : R01 HD068730
Pays : United States
Organisme : NICHD NIH HHS
ID : R01 HD094953
Pays : United States
Organisme : NIGMS NIH HHS
ID : R35 GM119465
Pays : United States
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
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