Christiane Klec

Affiliations

Division of Oncology, Department of Internal Medicine, Medical University of Graz (MUG), Graz, Austria.
Research Unit for Non-coding RNAs and Genome Editing, Medical University of Graz (MUG), Graz, Austria.

Publications (25)

MiR-1287-5p inhibits triple negative breast cancer growth by interaction with phosphoinositide 3-kinase CB, thereby sensitizing cells for PI3Kinase inhibitors.

Breast cancer research : BCR

Avec: Daniela Schwarzenbacher , Christiane Klec , Barbara Pasculli , Stefanie Cerk , Beate Rinner , Michael Karbiener , Cristina Ivan , Raffaela Barbano , Hui Ling , Annika Wulf-Goldenberg , Stefanie Stanzer , Gabriel Rinnerthaler , Herbert Stoeger , Thomas Bauernhofer , Johannes Haybaeck , Gerald Hoefler , Stephan Wenzel Jahn , Paola Parrella , George Adrian Calin , Martin Pichler

Lipid-independent control of endothelial and neuronal TRPC3 channels by light.

Chemical science

Avec: Oleksandra Tiapko , Niroj Shrestha , Sonja Lindinger , Gema Guedes de la Cruz , Annarita Graziani , Christiane Klec , Carmen Butorac , Wolfgang F Graier , Helmut Kubista , Marc Freichel , Lutz Birnbaumer , Christoph Romanin , Toma Glasnov , Klaus Groschner

Therapeutic potential of FLANC, a novel primate-specific long non-coding RNA in colorectal cancer.

Gut

Avec: Martin Pichler , Cristian Rodriguez-Aguayo , Su Youn Nam , Mihnea Paul Dragomir , Recep Bayraktar , Simone Anfossi , Erik Knutsen , Cristina Ivan , Enrique Fuentes-Mattei , Sang Kil Lee , Hui Ling , Tina Catela Ivkovic , Guoliang Huang , Li Huang , Yoshinaga Okugawa , Hiroyuki Katayama , Ayumu Taguchi , Emine Bayraktar , Rajat Bhattacharya , Paola Amero , William Ruixian He , Anh M Tran , Petra Vychytilova-Faltejskova , Christiane Klec , Diana L Bonilla , Xinna Zhang , Sanja Kapitanovic , Bozo Loncar , Roberta Gafà , Zhihui Wang , Vittorio Cristini , Samir M Hanash , Menashe Bar-Eli , Giovanni Lanza , Ondrej Slaby , Ajay Goel , Isidore Rigoutsos , Gabriel Lopez-Berestein , George Adrian Calin

MiR-200c-3p Modulates Cisplatin Resistance in Biliary Tract Cancer by ZEB1-Independent Mechanisms.

Cancers

Avec: Florian Posch , Felix Prinz , Amar Balihodzic , Christian Mayr , Tobias Kiesslich , Christiane Klec , Katharina Jonas , Dominik A Barth , Jakob M Riedl , Armin Gerger , Martin Pichler

ALYREF, a novel factor involved in breast carcinogenesis, acts through transcriptional and post-transcriptional mechanisms selectively regulating the short NEAT1 isoform.

Cellular and molecular life sciences : CMLS

Avec: Christiane Klec , Erik Knutsen , Daniela Schwarzenbacher , Katharina Jonas , Barbara Pasculli , Ellen Heitzer , Beate Rinner , Katarina Krajina , Felix Prinz , Benjamin Gottschalk , Peter Ulz , Alexander Deutsch , Andreas Prokesch , Stephan W Jahn , S Mohammad Lellahi , Maria Perander , Raffaela Barbano , Wolfgang F Graier , Paola Parrella , George Adrian Calin , Martin Pichler

Long Non-Coding RNA PANTR1 is Associated with Poor Prognosis and Influences Angiogenesis and Apoptosis in Clear-Cell Renal Cell Cancer.

Cancers

Avec: Maximilian Seles , Georg C Hutterer , Johannes Foßelteder , Marek Svoboda , Margit Resel , Dominik A Barth , Renate Pichler , Thomas Bauernhofer , Richard E Zigeuner , Karl Pummer , Ondrej Slaby , Christiane Klec , Martin Pichler

Development and Application of Sub-Mitochondrial Targeted Ca

Frontiers in cellular neuroscience

Avec: Markus Waldeck-Weiermair , Benjamin Gottschalk , Corina T Madreiter-Sokolowski , Jeta Ramadani-Muja , Gabriela Ziomek , Christiane Klec , Sandra Burgstaller , Helmut Bischof , Maria R Depaoli , Emrah Eroglu , Roland Malli , Wolfgang F Graier

Calcium Signaling in ß-cell Physiology and Pathology: A Revisit.

International journal of molecular sciences

Avec: Christiane Klec , Gabriela Ziomek , Martin Pichler , Roland Malli , Wolfgang F Graier

Cancer of Unknown Primary: Challenges and Progress in Clinical Management.

Cancers

Avec: Noemi Laprovitera , Mattia Riefolo , Elisa Ambrosini , Christiane Klec , Martin Pichler , Manuela Ferracin

MicroRNA mimics can distort physiological microRNA effects on immune checkpoints by triggering an antiviral interferon response.

RNA biology

Avec: Felix Prinz , Katharina Jonas , Amar Balihodzic , Christiane Klec , Andreas Reicher , Dominik Andreas Barth , Jakob Riedl , Armin Gerger , Tobias Kiesslich , Christian Mayr , Beate Rinner , Julia Kargl , Martin Pichler

MiR-4646-5p Acts as a Tumor-Suppressive Factor in Triple Negative Breast Cancer and Targets the Cholesterol Transport Protein GRAMD1B.

Non-coding RNA

Avec: Katharina Jonas , Felix Prinz , Manuela Ferracin , Katarina Krajina , Alexander Deutsch , Tobias Madl , Beate Rinner , Ondrej Slaby , Christiane Klec , Martin Pichler

Long-Noncoding RNA (lncRNA) in the Regulation of Hypoxia-Inducible Factor (HIF) in Cancer.

Non-coding RNA

Avec: Dominik A Barth , Felix Prinz , Julia Teppan , Katharina Jonas , Christiane Klec , Martin Pichler

Current Concepts of Non-Coding RNAs in the Pathogenesis of Non-Clear Cell Renal Cell Carcinoma.

Cancers

Avec: Dominik A Barth , Ondrej Slaby , Christiane Klec , Jaroslav Juracek , Rares Drula , George A Calin , Martin Pichler

The Implications of the Long Non-Coding RNA

International journal of molecular sciences

Avec: Felix Prinz , Anita Kapeller , Martin Pichler , Christiane Klec

Presenilin-1 Established ER-Ca

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Avec: Christiane Klec , Corina T Madreiter-Sokolowski , Gabriela Ziomek , Sarah Stryeck , Vinay Sachdev , Madalina Duta-Mare , Benjamin Gottschalk , Maria R Depaoli , Rene Rost , Jesse Hay , Markus Waldeck-Weiermair , Dagmar Kratky , Tobias Madl , Roland Malli , Wolfgang F Graier

Involvement of the long noncoding RNA NEAT1 in carcinogenesis.

Molecular oncology

Avec: Christiane Klec , Felix Prinz , Martin Pichler

Non-Coding RNAs and SARS-Related Coronaviruses.

Viruses

Avec: Hanna Henzinger , Dominik A Barth , Christiane Klec , Martin Pichler

Patterns of Peripheral Blood B-Cell Subtypes Are Associated With Treatment Response in Patients Treated With Immune Checkpoint Inhibitors: A Prospective Longitudinal Pan-Cancer Study.

Frontiers in immunology

Avec: Dominik A Barth , Stefanie Stanzer , Jasmin A Spiegelberg , Thomas Bauernhofer , Gudrun Absenger , Joanna Szkandera , Armin Gerger , Maria A Smolle , Georg C Hutterer , Sascha A Ahyai , Tobias Madl , Florian Posch , Jakob M Riedl , Christiane Klec , Philipp J Jost , Julia Kargl , Martin H Stradner , Martin Pichler

Involvement of long non-coding RNA HULC (highly up-regulated in liver cancer) in pathogenesis and implications for therapeutic intervention.

Expert opinion on therapeutic targets

Avec: Christiane Klec , Tony Gutschner , Katrin Panzitt , Martin Pichler

MICU1 controls cristae junction and spatially anchors mitochondrial Ca

Nature communications

Avec: Benjamin Gottschalk , Christiane Klec , Gerd Leitinger , Eva Bernhart , René Rost , Helmut Bischof , Corina T Madreiter-Sokolowski , Snježana Radulović , Emrah Eroglu , Wolfgang Sattler , Markus Waldeck-Weiermair , Roland Malli , Wolfgang F Graier

Glycogen Synthase Kinase 3 Beta Controls Presenilin-1-Mediated Endoplasmic Reticulum Ca²⁺ Leak Directed to Mitochondria in Pancreatic Islets and β-Cells.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Avec: Christiane Klec , Corina T Madreiter-Sokolowski , Sarah Stryeck , Vinay Sachdev , Madalina Duta-Mare , Benjamin Gottschalk , Maria R Depaoli , Rene Rost , Jesse Hay , Markus Waldeck-Weiermair , Dagmar Kratky , Tobias Madl , Roland Malli , Wolfgang F Graier

Enhanced inter-compartmental Ca

Redox biology

Avec: Corina T Madreiter-Sokolowski , Markus Waldeck-Weiermair , Marie-Pierre Bourguignon , Nicole Villeneuve , Benjamin Gottschalk , Christiane Klec , Sarah Stryeck , Snjezana Radulovic , Warisara Parichatikanond , Saša Frank , Tobias Madl , Roland Malli , Wolfgang F Graier

Involvement of Long Non-Coding RNAs (lncRNAs) in Tumor Angiogenesis.

Non-coding RNA

Avec: Julia Teppan , Dominik A Barth , Felix Prinz , Katharina Jonas , Martin Pichler , Christiane Klec

Evaluation of autoantibodies as predictors of treatment response and immune-related adverse events during the treatment with immune checkpoint inhibitors: A prospective longitudinal pan-cancer study.

Cancer medicine

Avec: Dominik A Barth , Stefanie Stanzer , Jasmin Spiegelberg , Thomas Bauernhofer , Gudrun Absenger , Florian Posch , Rainer Lipp , Michael Halm , Joanna Szkandera , Marija Balic , Armin Gerger , Maria A Smolle , Georg C Hutterer , Christiane Klec , Philipp J Jost , Julia Kargl , Martin Stradner , Martin Pichler

MiR-4649-5p acts as a tumor-suppressive microRNA in triple negative breast cancer by direct interaction with PIP5K1C, thereby potentiating growth-inhibitory effects of the AKT inhibitor capivasertib.

Breast cancer research : BCR

Avec: Katharina Jonas , Felix Prinz , Manuela Ferracin , Katarina Krajina , Barbara Pasculli , Alexander Deutsch , Tobias Madl , Beate Rinner , Ondrej Slaby , Christiane Klec , Martin Pichler

Réseau de co-auteurs

Martin Pichler 19 collaborations

Felix Prinz 9 collaborations

Wolfgang F Graier 8 collaborations

Dominik A Barth 8 collaborations

Katharina Jonas 7 collaborations

Benjamin Gottschalk 6 collaborations

Roland Malli 6 collaborations

Tobias Madl 6 collaborations

Beate Rinner 5 collaborations

Ondrej Slaby 5 collaborations

Markus Waldeck-Weiermair 5 collaborations

Corina T Madreiter-Sokolowski 5 collaborations

Thomas Bauernhofer 4 collaborations

Armin Gerger 4 collaborations

Barbara Pasculli 3 collaborations

Stefanie Stanzer 3 collaborations

George Adrian Calin 3 collaborations

Florian Posch 3 collaborations

Katarina Krajina 3 collaborations

Alexander Deutsch 3 collaborations

Georg C Hutterer 3 collaborations

Gabriela Ziomek 3 collaborations

Maria R Depaoli 3 collaborations

Manuela Ferracin 3 collaborations

Julia Kargl 3 collaborations

Sarah Stryeck 3 collaborations

Daniela Schwarzenbacher 2 collaborations

Cristina Ivan 2 collaborations

Raffaela Barbano 2 collaborations

Hui Ling 2 collaborations

Paola Parrella 2 collaborations

Erik Knutsen 2 collaborations

Amar Balihodzic 2 collaborations

Christian Mayr 2 collaborations

Tobias Kiesslich 2 collaborations

Jakob M Riedl 2 collaborations

Helmut Bischof 2 collaborations

Emrah Eroglu 2 collaborations

Julia Teppan 2 collaborations

Vinay Sachdev 2 collaborations

Madalina Duta-Mare 2 collaborations

Rene Rost 2 collaborations

Jesse Hay 2 collaborations

Dagmar Kratky 2 collaborations

Gudrun Absenger 2 collaborations

Joanna Szkandera 2 collaborations

Maria A Smolle 2 collaborations

Philipp J Jost 2 collaborations

Stefanie Cerk 1 collaboration

Michael Karbiener 1 collaboration

Annika Wulf-Goldenberg 1 collaboration

Gabriel Rinnerthaler 1 collaboration

Herbert Stoeger 1 collaboration

Johannes Haybaeck 1 collaboration

Gerald Hoefler 1 collaboration

Stephan Wenzel Jahn 1 collaboration

Oleksandra Tiapko 1 collaboration

Niroj Shrestha 1 collaboration

Sonja Lindinger 1 collaboration

Gema Guedes de la Cruz 1 collaboration

Annarita Graziani 1 collaboration

Carmen Butorac 1 collaboration

Helmut Kubista 1 collaboration

Marc Freichel 1 collaboration

Lutz Birnbaumer 1 collaboration

Christoph Romanin 1 collaboration

Toma Glasnov 1 collaboration

Klaus Groschner 1 collaboration

Cristian Rodriguez-Aguayo 1 collaboration

Su Youn Nam 1 collaboration

Mihnea Paul Dragomir 1 collaboration

Recep Bayraktar 1 collaboration

Simone Anfossi 1 collaboration

Enrique Fuentes-Mattei 1 collaboration

Sang Kil Lee 1 collaboration

Tina Catela Ivkovic 1 collaboration

Guoliang Huang 1 collaboration

Li Huang 1 collaboration

Yoshinaga Okugawa 1 collaboration

Hiroyuki Katayama 1 collaboration

Ayumu Taguchi 1 collaboration

Emine Bayraktar 1 collaboration

Rajat Bhattacharya 1 collaboration

Paola Amero 1 collaboration

William Ruixian He 1 collaboration

Anh M Tran 1 collaboration

Petra Vychytilova-Faltejskova 1 collaboration

Diana L Bonilla 1 collaboration

Xinna Zhang 1 collaboration

Sanja Kapitanovic 1 collaboration

Bozo Loncar 1 collaboration

Roberta Gafà 1 collaboration

Zhihui Wang 1 collaboration

Vittorio Cristini 1 collaboration

Samir M Hanash 1 collaboration

Menashe Bar-Eli 1 collaboration

Giovanni Lanza 1 collaboration

Ajay Goel 1 collaboration

Isidore Rigoutsos 1 collaboration

Gabriel Lopez-Berestein 1 collaboration

Ellen Heitzer 1 collaboration

Peter Ulz 1 collaboration

Andreas Prokesch 1 collaboration

Stephan W Jahn 1 collaboration

S Mohammad Lellahi 1 collaboration

Maria Perander 1 collaboration

Maximilian Seles 1 collaboration

Johannes Foßelteder 1 collaboration

Marek Svoboda 1 collaboration

Margit Resel 1 collaboration

Renate Pichler 1 collaboration

Richard E Zigeuner 1 collaboration

Karl Pummer 1 collaboration

Jeta Ramadani-Muja 1 collaboration

Sandra Burgstaller 1 collaboration

Noemi Laprovitera 1 collaboration

Mattia Riefolo 1 collaboration

Elisa Ambrosini 1 collaboration

Andreas Reicher 1 collaboration

Dominik Andreas Barth 1 collaboration

Jakob Riedl 1 collaboration

Jaroslav Juracek 1 collaboration

Rares Drula 1 collaboration

George A Calin 1 collaboration

Anita Kapeller 1 collaboration

Hanna Henzinger 1 collaboration

Jasmin A Spiegelberg 1 collaboration

Sascha A Ahyai 1 collaboration

Martin H Stradner 1 collaboration

Tony Gutschner 1 collaboration

Katrin Panzitt 1 collaboration

Gerd Leitinger 1 collaboration

Eva Bernhart 1 collaboration

René Rost 1 collaboration

Snježana Radulović 1 collaboration

Wolfgang Sattler 1 collaboration

Marie-Pierre Bourguignon 1 collaboration

Nicole Villeneuve 1 collaboration

Snjezana Radulovic 1 collaboration

Warisara Parichatikanond 1 collaboration

Saša Frank 1 collaboration

Jasmin Spiegelberg 1 collaboration

Rainer Lipp 1 collaboration

Michael Halm 1 collaboration

Marija Balic 1 collaboration

Martin Stradner 1 collaboration