Jacques Kiladjian

Affiliations

AP-HP, Hôpital Saint-Louis, Centre d'Investigations Cliniques, INSERM, CIC1427, Université Paris Cité, Paris, France.

Publications (95)

Long-term efficacy and safety of ruxolitinib versus best available therapy in polycythaemia vera (RESPONSE): 5-year follow up of a phase 3 study.

The Lancet. Haematology

Avec: Jean-Jacques Kiladjian , Pierre Zachee , Masayuki Hino , Fabrizio Pane , Tamas Masszi , Claire N Harrison , Ruben Mesa , Carole B Miller , Francesco Passamonti , Simon Durrant , Martin Griesshammer , Keita Kirito , Carlos Besses , Beatriz Moiraghi , Elisa Rumi , Vittorio Rosti , Igor Wolfgang Blau , Nathalie Francillard , Tuochuan Dong , Monika Wroclawska , Alessandro M Vannucchi , Srdan Verstovsek

Fedratinib, a newly approved treatment for patients with myeloproliferative neoplasm-associated myelofibrosis.

Leukemia

Avec: Moshe Talpaz , Jean-Jacques Kiladjian

Ropeginterferon alfa-2b versus standard therapy for polycythaemia vera (PROUD-PV and CONTINUATION-PV): a randomised, non-inferiority, phase 3 trial and its extension study.

The Lancet. Haematology

Avec: Heinz Gisslinger , Christoph Klade , Pencho Georgiev , Dorota Krochmalczyk , Liana Gercheva-Kyuchukova , Miklos Egyed , Viktor Rossiev , Petr Dulicek , Arpad Illes , Halyna Pylypenko , Lylia Sivcheva , Jiri Mayer , Vera Yablokova , Kurt Krejcy , Barbara Grohmann-Izay , Hans C Hasselbalch , Robert Kralovics , Jean-Jacques Kiladjian , Auteur inconnu

Should Transplantation Still Be Considered for Ph1-Negative Myeloproliferative Neoplasms in Transformation?

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation

Avec: Mathilde Ruggiu , Bruno Cassinat , Jean-Jacques Kiladjian , Emmanuel Raffoux , Stéphane Giraudier , Marie Robin , Raphael Itzykson , Emmanuelle Clappier , David Michonneau , Flore Sicre de Fontbrune , Régis Peffault de Latour , Lionel Ades , Gérard Socié

A Constitutional Activating

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Morad El Bouchtaoui , Marcio Do Cruzeiro , Christophe Leboeuf , Irmine Loisel-Ferreira , Carèle Fedronie , Chrystophe Ferreira , Rachida Ait El Far , Marianne Ziol , Marc Espié , Géraldine Falgarone , Bruno Cassinat , Jean-Jacques Kiladjian , Jean-Paul Feugeas , Anne Janin , Guilhem Bousquet

Next-generation sequencing for JAK2 mutation testing: advantages and pitfalls.

Annals of hematology

Avec: Nabih Maslah , Emmanuelle Verger , Marie-Helene Schlageter , Jean-Michel Miclea , Jean-Jacques Kiladjian , Stephane Giraudier , Christine Chomienne , Bruno Cassinat

Efficacy and tolerability of Janus kinase inhibitors in myelofibrosis: a systematic review and network meta-analysis.

Blood cancer journal

Avec: Léa Sureau , Corentin Orvain , Jean-Christophe Ianotto , Valérie Ugo , Jean-Jacques Kiladjian , Damien Luque Paz , Jérémie Riou

Appropriate management of polycythaemia vera with cytoreductive drug therapy: European LeukemiaNet 2021 recommendations.

The Lancet. Haematology

Avec: Monia Marchetti , Alessandro Maria Vannucchi , Martin Griesshammer , Claire Harrison , Steffen Koschmieder , Heinz Gisslinger , Alberto Álvarez-Larrán , Valerio De Stefano , Paola Guglielmelli , Francesca Palandri , Francesco Passamonti , Giovanni Barosi , Richard T Silver , Rüdiger Hehlmann , Jean-Jacques Kiladjian , Tiziano Barbui

Safety and efficacy of fedratinib, a selective oral inhibitor of Janus kinase-2 (JAK2), in patients with myelofibrosis and low pretreatment platelet counts.

British journal of haematology

Avec: Claire N Harrison , Nicolaas Schaap , Alessandro M Vannucchi , Jean-Jacques Kiladjian , Francesco Passamonti , Sonja Zweegman , Moshe Talpaz , Srdan Verstovsek , Shelonitda Rose , Jun Zhang , Oumar Sy , Ruben A Mesa

Momelotinib versus danazol in symptomatic patients with anaemia and myelofibrosis previously treated with a JAK inhibitor (MOMENTUM): an updated analysis of an international, double-blind, randomised phase 3 study.

The Lancet. Haematology

Avec: Aaron T Gerds , Srdan Verstovsek , Alessandro M Vannucchi , Haifa Kathrin Al-Ali , David Lavie , Andrew T Kuykendall , Sebastian Grosicki , Alessandra Iurlo , Yeow Tee Goh , Mihaela C Lazaroiu , Miklos Egyed , Maria Laura Fox , Donal McLornan , Andrew Perkins , Sung-Soo Yoon , Vikas Gupta , Jean-Jacques Kiladjian , Nikki Granacher , Sung-Eun Lee , Luminita Ocroteala , Francesco Passamonti , Claire N Harrison , Stephen Oh , Barbara J Klencke , Jing Yu , Rafe Donahue , Jun Kawashima , Ruben Mesa

Identifying Patients with Polycythemia Vera at Risk of Thrombosis after Hydroxyurea Initiation: The Polycythemia Vera-Advanced Integrated Models (PV-AIM) Project.

Biomedicines

Avec: Srdan Verstovsek , Ivan Krečak , Florian H Heidel , Valerio De Stefano , Kenneth Bryan , Mike W Zuurman , Michael Zaiac , Mara Morelli , Aoife Smyth , Santiago Redondo , Erwan Bigan , Michael Ruhl , Christoph Meier , Magali Beffy , Jean-Jacques Kiladjian

Incidence of COVID-19 mRNA vaccine symptomatic breakthrough infections during Omicron circulation in adults with or without infection prior to vaccination.

Infectious diseases now

Avec: Christine Durier , Laetitia Ninove , Sylvie van der Werf , Maeva Lefebvre , Corinne Desaint , Rebecca Bauer , Mikael Attia , Anne-Sophie Lecompte , Marie Lachatre , Zoha Maakaroun-Vermesse , Jean-François Nicolas , Renaud Verdon , Jean-Jacques Kiladjian , Paul Loubet , Catherine Schmidt-Mutter , Violaine Corbin , Séverine Ansart , Giovanna Melica , Martine Resch , Emmanuelle Netzer , Yousra Kherabi , Raphaëlle Tardieu , Jean-Daniel Lelièvre , Eric Tartour , Laurence Meyer , Xavier de Lamballerie , Odile Launay , Auteur inconnu

Changes in bone marrow fibrosis during momelotinib or ruxolitinib therapy do not correlate with efficacy outcomes in patients with myelofibrosis.

EJHaem

Avec: Stephen T Oh , Srdan Verstovsek , Vikas Gupta , Uwe Platzbecker , Timothy Devos , Jean-Jacques Kiladjian , Donal P McLornan , Andrew Perkins , Maria Laura Fox , Mary Frances McMullin , Adam J Mead , Miklos Egyed , Jiri Mayer , Tomasz Sacha , Jun Kawashima , Mei Huang , Bryan Strouse , Ruben Mesa

Myelofibrosis: Current unmet needs, emerging treatments, and future perspectives.

Cancer

Avec: Claire N Harrison , Jean-Jacques Kiladjian , Steffen Koschmieder , Francesco Passamonti

Serum and Salivary IgG and IgA Response After COVID-19 Messenger RNA Vaccination.

JAMA network open

Avec: Guy Gorochov , Jacques Ropers , Odile Launay , Karim Dorgham , Omaira da Mata-Jardin , Said Lebbah , Christine Durier , Rebecca Bauer , Anne Radenne , Corinne Desaint , Louis-Victorien Vieillard , Claire Rekacewicz , Marie Lachatre , Béatrice Parfait , Frédéric Batteux , Philippe Hupé , Läétitia Ninove , Maeva Lefebvre , Anne Conrad , Bertrand Dussol , Zoha Maakaroun-Vermesse , Giovanna Melica , Jean-François Nicolas , Renaud Verdon , Jean-Jacques Kiladjian , Paul Loubet , Catherine Schmidt-Mutter , Christian Dualé , Séverine Ansart , Elisabeth Botelho-Nevers , Jean-Daniel Lelièvre , Xavier de Lamballerie , Marie-Paule Kieny , Eric Tartour , Stéphane Paul

Pacritinib Response Is Associated With Overall Survival in Myelofibrosis: PERSIST-2 Landmark Analysis of Survival.

European journal of haematology

Avec: Helen Ajufo , Jan Philipp Bewersdorf , Claire Harrison , Francesca Palandri , John Mascarenhas , Jeanne Palmer , Aaron Gerds , Jean-Jacques Kiladjian , Sarah Buckley , Andriy Derkach , Karisse Roman-Torres , Raajit K Rampal

JAK2V617F myeloproliferative neoplasm eradication by a novel interferon/arsenic therapy involves PML.

The Journal of experimental medicine

Avec: Tracy Dagher , Nabih Maslah , Valérie Edmond , Bruno Cassinat , William Vainchenker , Stéphane Giraudier , Florence Pasquier , Emmanuelle Verger , Michiko Niwa-Kawakita , Valérie Lallemand-Breitenbach , Isabelle Plo , Jean-Jacques Kiladjian , Jean-Luc Villeval , Hugues de Thé

High mortality rate in COVID-19 patients with myeloproliferative neoplasms after abrupt withdrawal of ruxolitinib.

Leukemia

Avec: Tiziano Barbui , Alessandro Maria Vannucchi , Alberto Alvarez-Larran , Alessandra Iurlo , Arianna Masciulli , Alessandra Carobbio , Arianna Ghirardi , Alberto Ferrari , Giuseppe Rossi , Elena Elli , Marcio Miguel Andrade-Campos , Mercedes Gasior Kabat , Jean-Jaques Kiladjian , Francesca Palandri , Giulia Benevolo , Valentin Garcia-Gutierrez , Maria Laura Fox , Maria Angeles Foncillas , Carmen Montoya Morcillo , Elisa Rumi , Santiago Osorio , Petros Papadopoulos , Massimiliano Bonifacio , Keina Susana Quiroz Cervantes , Miguel Sagues Serrano , Gonzalo Carreno-Tarragona , Marta Anna Sobas , Francesca Lunghi , Andrea Patriarca , Begona Navas Elorza , Anna Angona , Elena Magro Mazo , Steffen Koschmieder , Marco Ruggeri , Beatriz Cuevas , Juan Carlos Hernandez-Boluda , Emma Lopez Abadia , Blanca Xicoy Cirici , Paola Guglielmelli , Marta Garrote , Daniele Cattaneo , Rosa Daffini , Fabrizio Cavalca , Beatriz Bellosillo , Lina Benajiba , Natalia Curto-Garcia , Marta Bellini , Silvia Betti , Valerio De Stefano , Claire Harrison , Alessandro Rambaldi

MOMENTUM: momelotinib vs danazol in patients with myelofibrosis previously treated with JAKi who are symptomatic and anemic.

Future oncology (London, England)

Avec: Srdan Verstovsek , Chih-Cheng Chen , Miklós Egyed , Martin Ellis , Laura Fox , Yeow T Goh , Vikas Gupta , Claire Harrison , Jean-Jacques Kiladjian , Mihaela C Lazaroiu , Adam Mead , Donal McLornan , Mary F McMullin , Stephen T Oh , Andrew Perkins , Uwe Platzbecker , Christof Scheid , Alessandro Vannucchi , Sung-Soo Yoon , Mark M Kowalski , Ruben A Mesa

Determining the recommended dose of pacritinib: results from the PAC203 dose-finding trial in advanced myelofibrosis.

Blood advances

Avec: Aaron T Gerds , Michael R Savona , Bart L Scott , Moshe Talpaz , Miklos Egyed , Claire N Harrison , Abdulraheem Yacoub , Alessandro Vannucchi , Adam J Mead , Jean-Jacques Kiladjian , Jennifer O'Sullivan , Valentin García-Gutiérrez , Prithviraj Bose , Raajit K Rampal , Carole B Miller , Jeanne Palmer , Stephen T Oh , Sarah A Buckley , Diane R Mould , Kaori Ito , Shanthakumar Tyavanagimatt , Jennifer A Smith , Karisse Roman-Torres , Sri Devineni , Adam R Craig , John O Mascarenhas

Pegcetacoplan versus Eculizumab in Paroxysmal Nocturnal Hemoglobinuria.

The New England journal of medicine

Avec: Peter Hillmen , Jeff Szer , Ilene Weitz , Alexander Röth , Britta Höchsmann , Jens Panse , Kensuke Usuki , Morag Griffin , Jean-Jacques Kiladjian , Carlos de Castro , Hisakazu Nishimori , Lisa Tan , Mohamed Hamdani , Pascal Deschatelets , Cedric Francois , Federico Grossi , Temitayo Ajayi , Antonio Risitano , Régis Peffault de la Tour

Long-term outcome of imatinib 400 mg compared to imatinib 600 mg or imatinib 400 mg daily in combination with cytarabine or pegylated interferon alpha 2a for chronic myeloid leukaemia: results from the French SPIRIT phase III randomised trial.

Leukemia

Avec: Francois Guilhot , Françoise Rigal-Huguet , Joëlle Guilhot , Agnès-Paule Guerci-Bresler , Frédéric Maloisel , Delphine Rea , Valérie Coiteux , Martine Gardembas , Christian Berthou , Anne Vekhoff , Eric Jourdan , Marc Berger , Loïc Fouillard , Magda Alexis , Laurence Legros , Philippe Rousselot , Alain Delmer , Pascal Lenain , Martine Escoffre Barbe , Emmanuel Gyan , Claude-Eric Bulabois , Viviane Dubruille , Bertrand Joly , Bertrand Pollet , Pascale Cony-Makhoul , Hyacinthe Johnson-Ansah , Melanie Mercier , Denis Caillot , Aude Charbonnier , Jean-Jacques Kiladjian , Jacques Chapiro , Amélie Penot , Véronique Dorvaux , Iona Vaida , Alberto Santagostino , Lydia Roy , Hacene Zerazhi , Eric Deconinck , Herve Maisonneuve , Isabelle Plantier , Delphine Lebon , Yazid Arkam , Nathalie Cambier , Kamel Ghomari , Jean-Michel Miclea , Sylvie Glaisner , Jean-Michel Cayuela , Jean-Claude Chomel , Marc Muller , Ludovic Lhermitte , Marc Delord , Claude Preudhomme , Gabriel Etienne , François-Xavier Mahon , Franck-Emmanuel Nicolini , Auteur inconnu

Rare and private spliceosomal gene mutations drive partial, complete, and dual phenocopies of hotspot alterations.

Blood

Avec: Joseph Pangallo , Jean-Jacques Kiladjian , Bruno Cassinat , Aline Renneville , Justin Taylor , Jacob T Polaski , Khrystyna North , Omar Abdel-Wahab , Robert K Bradley

Pitfalls in CALR exon 9 mutation detection: A single-center experience in 571 positive patients.

International journal of laboratory hematology

Avec: Emmanuelle Verger , Nabih Maslah , Marie-Helene Schlageter , Christine Chomienne , Jean-Jacques Kiladjian , Stephane Giraudier , Bruno Cassinat

Perspective: Pivotal translational hematology and therapeutic insights in chronic myeloid hematopoietic stem cell malignancies.

Hematological oncology

Avec: Tariq I Mughal , Naveen Pemmaraju , Rafael Bejar , Robert P Gale , Prithviraj Bose , Jean-Jacques Kiladjian , Josef Prchal , Daniel Royston , Daniel Pollyea , Peter Valent , Tim H Brümmendorf , Tomasz Skorski , Mrinal Patnaik , Valeria Santini , Pierre Fenaux , Nicole Kucine , Srdan Verstovsek , Ruben Mesa , Tiziano Barbui , Guiseppe Saglio , Richard A Van Etten

An inherited gain-of-function risk allele in EPOR predisposes to familial JAK2

British journal of haematology

Avec: Graciela Rabadan Moraes , Florence Pasquier , Christophe Marzac , Eric Deconinck , Carlotta Caterina Damanti , Gwendoline Leroy , Mira El-Khoury , Wassim El Nemer , Jean-Jacques Kiladjian , Hana Raslova , Albert Najman , William Vainchenker , Caroline Marty , Christine Bellanné-Chantelot , Isabelle Plo

ROP-ET: a prospective phase III trial investigating the efficacy and safety of ropeginterferon alfa-2b in essential thrombocythemia patients with limited treatment options.

Annals of hematology

Avec: Jean-Jacques Kiladjian , Francisca Ferrer Marin , Haifa Kathrin Al-Ali , Alberto Alvarez-Larrán , Eloise Beggiato , Maria Bieniaszewska , Massimo Breccia , Veronika Buxhofer-Ausch , Olga Cerna , Ana-Manuela Crisan , Catalin Doru Danaila , Valerio De Stefano , Konstanze Döhner , Victoria Empson , Joanna Gora-Tybor , Martin Griesshammer , Sebastian Grosicki , Paola Guglielmelli , Valentin García-Gutierrez , Florian H Heidel , Arpád Illés , Ciprian Tomuleasa , Chloe James , Steffen Koschmieder , Maria-Theresa Krauth , Kurt Krejcy , Mihaela-Cornelia Lazaroiu , Jiri Mayer , Zsolt György Nagy , Franck-Emmanuel Nicolini , Francesca Palandri , Vassiliki Pappa , Andreas Johannes Reiter , Tomasz Sacha , Stefanie Schlager , Stefan Schmidt , Evangelos Terpos , Martin Unger , Albert Wölfler , Blanca Xicoy Cirici , Christoph Klade

Myeloproliferative neoplasms: young patients, current data and future considerations.

Annals of hematology

Avec: Marta Sobas , Jean-Christophe Ianotto , Jean-Jacques Kiladjian , Claire Harrison

Myeloproliferative neoplasms in the adolescent and young adult population: A comprehensive review of the literature.

British journal of haematology

Avec: Hannah Goulart , Lucia Masarova , Ruben Mesa , Claire Harrison , Jean-Jacques Kiladjian , Naveen Pemmaraju

Efficacy and safety of ruxolitinib in patients with myelofibrosis and low platelet count (50 × 10

Therapeutic advances in hematology

Avec: Paola Guglielmelli , Jean-Jacques Kiladjian , Alessandro M Vannucchi , Minghui Duan , Haitao Meng , Ling Pan , Guangsheng He , Srdan Verstovsek , Françoise Boyer , Fiorenza Barraco , Dietger Niederwieser , Ester Pungolino , Anna Marina Liberati , Claire Harrison , Pantelia Roussou , Monika Wroclawska , Divyadeep Karumanchi , Karen Sinclair , Peter A W Te Boekhorst , Heinz Gisslinger

Early intervention in myelofibrosis and impact on outcomes: A pooled analysis of the COMFORT-I and COMFORT-II studies.

Cancer

Avec: Srdan Verstovsek , Jean-Jacques Kiladjian , Alessandro M Vannucchi , Ruben A Mesa , Peg Squier , J E Hamer-Maansson , Claire Harrison

Incidence of blast phase in myelofibrosis according to anemia severity.

EJHaem

Avec: Barbara Mora , Margherita Maffioli , Elisa Rumi , Paola Guglielmelli , Marianna Caramella , Andrew Kuykendall , Francesca Palandri , Alessandra Iurlo , Valerio De Stefano , Jean-Jacques Kiladjian , Elena M Elli , Nicola Polverelli , Jason Gotlib , Francesco Albano , Richard T Silver , Giulia Benevolo , David M Ross , Timothy Devos , Oscar Borsani , Tiziano Barbui , Matteo G Della Porta , Lorenza Bertù , Rami Komrokji , Alessandro M Vannucchi , Francesco Passamonti

Inequality factors in access to early-phase clinical trials in oncology in France: results of the EGALICAN-2 study.

ESMO open

Avec: E Charton , C Baldini , Y Fayet , E Schultz , L Auroy , E Vallier , A Italiano , M Robert , E Coquan , N Isambert , P Moreau , C Touzeau , C Le Tourneau , Z Ghrieb , J-J Kiladjian , J-P Delord , C Gomez Roca , N Vey , F Barlesi , T Lesimple , N Penel , J-C Soria , C Massard , S Besle

Clinical outcomes of patients with myelofibrosis after immediate transition to momelotinib from ruxolitinib.

Haematologica

Avec: Ruben Mesa , Srdan Verstovsek , Uwe Platzbecker , Vikas Gupta , David Lavie , Pilar Giraldo , Christian Recher , Jean-Jacques Kiladjian , Stephen T Oh , Aaron T Gerds , Timothy Devos , Francesco Passamonti , Alessandro M Vannucchi , Miklos Egyed , Ewa Lech-Maranda , Andrzej Pluta , Lars Nilsson , Kazuya Shimoda , Donal McLornan , Jun Kawashima , Barbara Klencke , Mei Huang , Bryan Strouse , Claire Harrison

Genomic and functional impact of Trp53 inactivation in JAK2V617F myeloproliferative neoplasms.

Blood cancer journal

Avec: Panhong Gou , Duanya Liu , Saravanan Ganesan , Evelyne Lauret , Nabih Maslah , Veronique Parietti , Wenchao Zhang , Véronique Meignin , Jean-Jacques Kiladjian , Bruno Cassinat , Stephane Giraudier

Patient-reported Outcomes and Quality of Life in Anemic and Symptomatic Patients With Myelofibrosis: Results From the MOMENTUM Study.

HemaSphere

Avec: Ruben A Mesa , Claire Harrison , Jeanne M Palmer , Vikas Gupta , Donal P McLornan , Mary Frances McMullin , Jean-Jacques Kiladjian , Lynda Foltz , Uwe Platzbecker , Maria Laura Fox , Adam J Mead , David M Ross , Stephen T Oh , Andrew Charles Perkins , Michael F Leahy , Jun Kawashima , Sunhee Ro , Rafe Donahue , Boris Gorsh , Samineh Deheshi , Srdan Verstovsek

Current myeloproliferative neoplasm scoring systems for clinical practice.

Blood

Avec: Hélène Pasquer , Jean-Jacques Kiladjian , Lina Benajiba

Safety and efficacy findings from the open-label, multicenter, phase 3b, expanded treatment protocol study of ruxolitinib for treatment of patients with polycythemia vera who are resistant/intolerant to hydroxyurea and for whom no alternative treatments are available.

Leukemia & lymphoma

Avec: Lynda Foltz , Gian-Matteo Pica , Hacene Zerazhi , Jan Van Droogenbroeck , Sorin Visanica , Enrique Báez de la Fuente , Brian Leber , Antonio Medina de Almeida , Dana Ranta , Jean-Jacques Kiladjian , Linda Chrit , Albert Kandra , Juliane Morando , Timothy Devos

Fedratinib in patients with myelofibrosis previously treated with ruxolitinib: An updated analysis of the JAKARTA2 study using stringent criteria for ruxolitinib failure.

American journal of hematology

Avec: Claire N Harrison , Nicolaas Schaap , Alessandro M Vannucchi , Jean-Jacques Kiladjian , Eric Jourdan , Richard T Silver , Harry C Schouten , Francesco Passamonti , Sonja Zweegman , Moshe Talpaz , Srdan Verstovsek , Shelonitda Rose , Juan Shen , Tymara Berry , Carrie Brownstein , Ruben A Mesa

Ruxolitinib before allogeneic hematopoietic transplantation in patients with myelofibrosis on behalf SFGM-TC and FIM groups.

Bone marrow transplantation

Avec: Marie Robin , Raphael Porcher , Corentin Orvain , Jacques-Olivier Bay , Fiorenza Barraco , Anne Huynh , Amandine Charbonnier , Edouard Forcade , Sylvain Chantepie , Claude Bulabois , Ibrahim Yakoub-Agha , Marie Detrait , David Michonneau , Pascal Turlure , Nicole Raus , Françoise Boyer , Felipe Suarez , Laure Vincent , Stéphanie N Guyen , Jérôme Cornillon , Alban Villate , Brigitte Dupriez , Bruno Cassinat , Valérie Rolland , Marie Hélène Schlageter , Gérard Socié , Jean-Jacques Kiladjian

ABCG2 Is Overexpressed on Red Blood Cells in Ph-Negative Myeloproliferative Neoplasms and Potentiates Ruxolitinib-Induced Apoptosis.

International journal of molecular sciences

Avec: Ralfs Buks , Mégane Brusson , Sylvie Cochet , Tatiana Galochkina , Bruno Cassinat , Ivan Nemazanyy , Thierry Peyrard , Jean-Jacques Kiladjian , Alexandre G de Brevern , Slim Azouzi , Wassim El Nemer

Splenectomy before allogeneic hematopoietic cell transplantation for myelofibrosis: A French nationwide study.

American journal of hematology

Avec: Jean-Baptiste Bossard , Jean-Baptiste Beuscart , Marie Robin , Mohamad Mohty , Fiorenza Barraco , Patrice Chevallier , Tony Marchand , Marie-Thérèse Rubio , Amandine Charbonnier , Didier Blaise , Jacques-Olivier Bay , Carmen Botella-Garcia , Gandhi Damaj , Florence Beckerich , Patrice Ceballos , Thomas Cluzeau , Jérôme Cornillon , Mathieu Meunier , Corentin Orvain , Alain Duhamel , Federico Garnier , Jean-Jacques Kiladjian , Ibrahim Yakoub-Agha , Auteur inconnu

Avadomide induces degradation of ZMYM2 fusion oncoproteins in hematologic malignancies.

Blood cancer discovery

Avec: Aline Renneville , Jessica A Gasser , Daniel E Grinshpun , Pierre M Jean Beltran , Namrata D Udeshi , Mary E Matyskiela , Thomas Clayton , Marie McConkey , Kaushik Viswanathan , Alexander Tepper , Andrew A Guirguis , Rob S Sellar , Sophie Cotteret , Christophe Marzac , Véronique Saada , Stéphane De Botton , Jean-Jacques Kiladjian , Jean-Michel Cayuela , Mark Rolfe , Philip P Chamberlain , Steven A Carr , Benjamin L Ebert

Fedratinib Improves Myelofibrosis-related Symptoms and Health-related Quality of Life in Patients with Myelofibrosis Previously Treated with Ruxolitinib: Patient-reported Outcomes from the Phase II JAKARTA2 Trial.

HemaSphere

Avec: Claire N Harrison , Nicolaas Schaap , Alessandro M Vannucchi , Jean-Jacques Kiladjian , Eric Jourdan , Richard T Silver , Harry C Schouten , Francesco Passamonti , Sonja Zweegman , Moshe Talpaz , Srdan Verstovsek , Derek Tang , Pranav Abraham , Jennifer Lord-Bessen , Shelonitda Rose , Shien Guo , Weiqin Liao , Ruben A Mesa

First-in-human study of naporafenib (LXH254) with or without spartalizumab in adult patients with advanced solid tumors harboring MAPK signaling pathway alterations.

European journal of cancer (Oxford, England : 1990)

Avec: Filip Janku , Tae Min Kim , Gopakumar Iyer , Anna Spreafico , Elena Elez , Maja de Jonge , Noboru Yamamoto , Anthonie J van der Wekken , Paolo Antonio Ascierto , Michela Maur , Frederik Marmé , Jean-Jacques Kiladjian , Sumit Basu , Fabienne Baffert , Amparo Buigues , Chi Chen , Vesselina Cooke , Elisa Giorgetti , Jaeyeon Kim , Fiona McCarthy , Michele Moschetta , Reinhard Dummer

Overall survival in the SIMPLIFY-1 and SIMPLIFY-2 phase 3 trials of momelotinib in patients with myelofibrosis.

Leukemia

Avec: Ruben Mesa , Claire Harrison , Stephen T Oh , Aaron T Gerds , Vikas Gupta , John Catalano , Francisco Cervantes , Timothy Devos , Marek Hus , Jean-Jacques Kiladjian , Ewa Lech-Maranda , Donal McLornan , Alessandro M Vannucchi , Uwe Platzbecker , Mei Huang , Bryan Strouse , Barbara Klencke , Srdan Verstovsek

International Consensus Classification of Myeloid Neoplasms and Acute Leukemias: integrating morphologic, clinical, and genomic data.

Blood

Avec: Daniel A Arber , Attilio Orazi , Robert P Hasserjian , Michael J Borowitz , Katherine R Calvo , Hans-Michael Kvasnicka , Sa A Wang , Adam Bagg , Tiziano Barbui , Susan Branford , Carlos E Bueso-Ramos , Jorge E Cortes , Paola Dal Cin , Courtney D DiNardo , Hervé Dombret , Eric J Duncavage , Benjamin L Ebert , Elihu H Estey , Fabio Facchetti , Kathryn Foucar , Naseema Gangat , Umberto Gianelli , Lucy A Godley , Nicola Gökbuget , Jason Gotlib , Eva Hellström-Lindberg , Gabriela S Hobbs , Ronald Hoffman , Elias J Jabbour , Jean-Jacques Kiladjian , Richard A Larson , Michelle M Le Beau , Mignon L-C Loh , Bob Löwenberg , Elizabeth Macintyre , Luca Malcovati , Charles G Mullighan , Charlotte Niemeyer , Olatoyosi M Odenike , Seishi Ogawa , Alberto Orfao , Elli Papaemmanuil , Francesco Passamonti , Kimmo Porkka , Ching-Hon Pui , Jerald P Radich , Andreas Reiter , Maria Rozman , Martina Rudelius , Michael R Savona , Charles A Schiffer , Annette Schmitt-Graeff , Akiko Shimamura , Jorge Sierra , Wendy A Stock , Richard M Stone , Martin S Tallman , Jürgen Thiele , Hwei-Fang Tien , Alexandar Tzankov , Alessandro M Vannucchi , Paresh Vyas , Andrew H Wei , Olga K Weinberg , Agnieszka Wierzbowska , Mario Cazzola , Hartmut Döhner , Ayalew Tefferi

Pegcetacoplan versus eculizumab in patients with paroxysmal nocturnal haemoglobinuria (PEGASUS): 48-week follow-up of a randomised, open-label, phase 3, active-comparator, controlled trial.

The Lancet. Haematology

Avec: Régis Peffault de Latour , Jeff Szer , Ilene C Weitz , Alexander Röth , Britta Höchsmann , Jens Panse , Kensuke Usuki , Morag Griffin , Jean-Jacques Kiladjian , Carlos M de Castro , Hisakazu Nishimori , Temitayo Ajayi , Mohammed Al-Adhami , Pascal Deschatelets , Cedric Francois , Federico Grossi , Antonio M Risitano , Peter Hillmen

Prediction of thrombosis in post-polycythemia vera and post-essential thrombocythemia myelofibrosis: a study on 1258 patients.

Leukemia

Avec: Barbara Mora , Paola Guglielmelli , Andrew Kuykendall , Elisa Rumi , Margherita Maffioli , Francesca Palandri , Valerio De Stefano , Marianna Caramella , Silvia Salmoiraghi , Jean-Jacques Kiladjian , Jason Gotlib , Alessandra Iurlo , Francisco Cervantes , Marco Ruggeri , Richard T Silver , Francesco Albano , Giulia Benevolo , David M Ross , Matteo G Della Porta , Timothy Devos , Giada Rotunno , Rami S Komrokji , Ilaria C Casetti , Michele Merli , Marco Brociner , Domenica Caramazza , Giuseppe Auteri , Tiziano Barbui , Daniele Cattaneo , Lorenza Bertù , Luca Arcaini , Alessandro M Vannucchi , Francesco Passamonti

BOREAS: a global, phase III study of the MDM2 inhibitor navtemadlin (KRT-232) in relapsed/refractory myelofibrosis.

Future oncology (London, England)

Avec: Srdan Verstovsek , Haifa Kathrin Al-Ali , John Mascarenhas , Andrew Perkins , Alessandro Maria Vannucchi , Sanjay R Mohan , Bart L Scott , Dariusz Woszczyk , Steffen Koschmieder , Regina García-Delgado , Rejtő László , Jesse S McGreivy , Wayne P Rothbaum , Jean-Jacques Kiladjian

Neutralizing antibodies against SARS-CoV-2 variants following mRNA booster vaccination in adults older than 65 years.

Scientific reports

Avec: Christine Durier , Laetitia Ninove , Maeva Lefebvre , Anne Radenne , Corinne Desaint , Jacques Ropers , Rebecca Bauer , Said Lebbah , Diane Carette , Marie Lachatre , Anne-Sophie Lecompte , Dominique Deplanque , Elisabeth Botelho-Nevers , Anne Conrad , Bertrand Dussol , Zoha Maakaroun-Vermesse , Giovanna Melica , Jean-François Nicolas , Renaud Verdon , Jacques Kiladjian , Paul Loubet , Catherine Schmidt-Mutter , Christian Dualé , Séverine Ansart , Stéphane Priet , Axel Levier , Diana Molino , Louis-Victorien Vieillard , Béatrice Parfait , Jean-Daniel Lelièvre , Eric Tartour , Xavier de Lamballerie , Odile Launay , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu

Biological drivers of clinical phenotype in myelofibrosis.

Leukemia

Avec: John Mascarenhas , Hélène F E Gleitz , Helen T Chifotides , Claire N Harrison , Srdan Verstovsek , Alessandro Maria Vannucchi , Raajit K Rampal , Jean-Jacques Kiladjian , William Vainchenker , Ronald Hoffman , Rebekka K Schneider , Alan F List

Phase III MANIFEST-2: pelabresib + ruxolitinib vs placebo + ruxolitinib in JAK inhibitor treatment-naive myelofibrosis.

Future oncology (London, England)

Avec: Claire N Harrison , Vikas K Gupta , Aaron T Gerds , Raajit Rampal , Srdan Verstovsek , Moshe Talpaz , Jean-Jacques Kiladjian , Ruben Mesa , Andrew T Kuykendall , Alessandro M Vannucchi , Francesca Palandri , Sebastian Grosicki , Timothy Devos , Eric Jourdan , Marielle J Wondergem , Haifa Kathrin Al-Ali , Veronika Buxhofer-Ausch , Alberto Alvarez-Larrán , Andrea Patriarca , Marina Kremyanskaya , Adam J Mead , Sanjay Akhani , Yuri Sheikine , Gozde Colak , John Mascarenhas

Momelotinib long-term safety and survival in myelofibrosis: integrated analysis of phase 3 randomized controlled trials.

Blood advances

Avec: Srdan Verstovsek , Ruben Mesa , Vikas Gupta , David Lavie , Viviane Dubruille , Nathalie Cambier , Uwe Platzbecker , Marek Hus , Blanca Xicoy , Stephen T Oh , Jean-Jacques Kiladjian , Alessandro M Vannucchi , Aaron Gerds , Miklos Egyed , Jiří Mayer , Tomasz Sacha , Jun Kawashima , Marc Morris , Mei Huang , Claire Harrison

Pacritinib is a potent ACVR1 inhibitor with significant anemia benefit in patients with myelofibrosis.

Blood advances

Avec: Stephen T Oh , Ruben A Mesa , Claire N Harrison , Prithviraj Bose , Aaron T Gerds , Vikas Gupta , Bart L Scott , Jean-Jacques Kiladjian , Alessandro Lucchesi , Tim Kong , Sarah A Buckley , Shanthakumar Tyavanagimatt , Bryan G Harder , Karisse Roman-Torres , Jennifer Smith , Adam R Craig , John Mascarenhas , Srdan Verstovsek

Safety and efficacy of fedratinib in patients with myelofibrosis previously treated with ruxolitinib: primary analysis of FREEDOM trial.

Leukemia & lymphoma

Avec: Vikas Gupta , Abdulraheem Yacoub , Ruben A Mesa , Claire N Harrison , Alessandro M Vannucchi , Jean-Jacques Kiladjian , Hans-Joachim Deeg , Salman Fazal , Lynda Foltz , Ryan J Mattison , Carole B Miller , Vinod Parameswaran , Patrick Brown , Christopher Hernandez , Jia Wang , Moshe Talpaz

Illuminating novel biological aspects and potential new therapeutic approaches for chronic myeloproliferative malignancies.

Hematological oncology

Avec: Tariq I Mughal , Naveen Pemmaraju , Bethan Psaila , Jerald Radich , Prithviraj Bose , Thomas Lion , Jean-Jacques Kiladjian , Raajit Rampal , Tania Jain , Srdnan Verstovsek , Abdulraheem Yacoub , Jorge E Cortes , Ruben Mesa , Giuseppe Saglio , Richard A van Etten

Genomic analysis of primary and secondary myelofibrosis redefines the prognostic impact of ASXL1 mutations: a FIM study.

Blood advances

Avec: Damien Luque Paz , Jérémie Riou , Emmanuelle Verger , Bruno Cassinat , Aurélie Chauveau , Jean-Christophe Ianotto , Brigitte Dupriez , Françoise Boyer , Maxime Renard , Olivier Mansier , Anne Murati , Jérôme Rey , Gabriel Etienne , Véronique Mansat-De Mas , Suzanne Tavitian , Olivier Nibourel , Stéphane Girault , Yannick Le Bris , François Girodon , Dana Ranta , Jean-Claude Chomel , Pascale Cony-Makhoul , Pierre Sujobert , Margot Robles , Raouf Ben Abdelali , Olivier Kosmider , Laurane Cottin , Lydia Roy , Ivan Sloma , Fabienne Vacheret , Mathieu Wemeau , Pascal Mossuz , Borhane Slama , Vincent Cussac , Guillaume Denis , Anouk Walter-Petrich , Barbara Burroni , Nathalie Jézéquel , Stéphane Giraudier , Eric Lippert , Gérard Socié , Jean-Jacques Kiladjian , Valérie Ugo

PPARγ agonists promote the resolution of myelofibrosis in preclinical models.

The Journal of clinical investigation

Avec: Juliette Lambert , Joseph Saliba , Carolina Calderon , Karine Sii-Felice , Mohammad Salma , Valérie Edmond , Jean-Claude Alvarez , Marc Delord , Caroline Marty , Isabelle Plo , Jean-Jacques Kiladjian , Eric Soler , William Vainchenker , Jean-Luc Villeval , Philippe Rousselot , Stéphane Prost

[An example of Clinical Investigations Center reorganization during the COVID-19 pandemic French national lockdown].

Therapie

Avec: Zineb Ghrieb , Souhil Allaoua , Jin Huang , Nathalie Langner , Florène François , Corinne Maréchal , Majdi Jebali , Céleste Lebbé , Abdennour Chellah , Anne Bergeron , Jean-Jacques Kiladjian , Rafael Daltro De Oliveira , Juliette Soret-Dulphy , Lina Benajiba

Among classic myeloproliferative neoplasms, essential thrombocythemia is associated with the greatest risk of venous thromboembolism during COVID-19.

Blood cancer journal

Avec: Tiziano Barbui , Valerio De Stefano , Alberto Alvarez-Larran , Alessandra Iurlo , Arianna Masciulli , Alessandra Carobbio , Arianna Ghirardi , Alberto Ferrari , Valeria Cancelli , Elena Maria Elli , Marcio Miguel Andrade-Campos , Mercedes Gasior Kabat , Jean-Jaques Kiladjian , Francesca Palandri , Giulia Benevolo , Valentin Garcia-Gutierrez , Maria Laura Fox , Maria Angeles Foncillas , Carmen Montoya Morcillo , Elisa Rumi , Santiago Osorio , Petros Papadopoulos , Massimiliano Bonifacio , Keina Susana Quiroz Cervantes , Miguel Sagues Serrano , Gonzalo Carreno-Tarragona , Marta Anna Sobas , Francesca Lunghi , Andrea Patriarca , Begoña Navas Elorza , Anna Angona , Elena Magro Mazo , Steffen Koschmieder , Giuseppe Carli , Beatriz Cuevas , Juan Carlos Hernandez-Boluda , Emma Lopez Abadia , Blanca Xicoy Cirici , Paola Guglielmelli , Marta Garrote , Daniele Cattaneo , Rosa Daffini , Fabrizio Cavalca , Beatriz Bellosillo , Lina Benajiba , Natalia Curto-Garcia , Marta Bellini , Silvia Betti , Claire Harrison , Alessandro Rambaldi , Alessandro Maria Vannucchi

Revisiting Diagnostic performances of serum erythropoïetin level and JAK2 mutation for polycythemias: analysis of a cohort of 1090 patients with red cell mass measurement.

British journal of haematology

Avec: Nabih Maslah , Odonchimeg Ravdan , Louis Drevon , Emmanuelle Verger , Célia Belkhodja , Christine Chomienne , Bruno Cassinat , Jean-Jacques Kiladjian , Stéphane Giraudier , Marie-Hélène Schlageter

Altered Ca

Cells

Avec: Ralfs Buks , Tracy Dagher , Maria Giustina Rotordam , David Monedero Alonso , Sylvie Cochet , Emilie-Fleur Gautier , Philippe Chafey , Bruno Cassinat , Jean-Jacques Kiladjian , Nadine Becker , Isabelle Plo , Stéphane Egée , Wassim El Nemer

Single-cell analysis reveals selection of TP53-mutated clones after MDM2 inhibition.

Blood advances

Avec: Nabih Maslah , Emmanuelle Verger , Stéphane Giraudier , Mathias Chea , Ronald Hoffman , John Mascarenhas , Bruno Cassinat , Jean-Jacques Kiladjian

A randomized phase 3 trial of interferon-α vs hydroxyurea in polycythemia vera and essential thrombocythemia.

Blood

Avec: John Mascarenhas , Heidi E Kosiorek , Josef T Prchal , Alessandro Rambaldi , Dmitriy Berenzon , Abdulraheem Yacoub , Claire N Harrison , Mary Frances McMullin , Alessandro M Vannucchi , Joanne Ewing , Casey L O'Connell , Jean-Jacques Kiladjian , Adam J Mead , Elliott F Winton , David S Leibowitz , Valerio De Stefano , Murat O Arcasoy , Craig M Kessler , Rosalind Catchatourian , Damiano Rondelli , Richard T Silver , Andrea Bacigalupo , Arnon Nagler , Marina Kremyanskaya , Max F Levine , Juan E Arango Ossa , Erin McGovern , Lonette Sandy , Mohamad E Salama , Vesna Najfeld , Joseph Tripodi , Noushin Farnoud , Alexander V Penson , Rona Singer Weinberg , Leah Price , Judith D Goldberg , Tiziano Barbui , Roberto Marchioli , Gianni Tognoni , Raajit K Rampal , Ruben A Mesa , Amylou C Dueck , Ronald Hoffman

Imetelstat in intermediate-2 or high-risk myelofibrosis refractory to JAK inhibitor: IMpactMF phase III study design.

Future oncology (London, England)

Avec: John Mascarenhas , Claire N Harrison , Jean-Jacques Kiladjian , Rami S Komrokji , Steffen Koschmieder , Alessandro M Vannucchi , Tymara Berry , Denise Redding , Laurie Sherman , Souria Dougherty , Lixian Peng , Libo Sun , Fei Huang , Ying Wan , Faye M Feller , Aleksandra Rizo , Srdan Verstovsek

Real-world study of children and young adults with myeloproliferative neoplasms: identifying risks and unmet needs.

Blood advances

Avec: Marta Sobas , Jean-Jacques Kiladjian , Yan Beauverd , Natalia Curto-Garcia , Parvis Sadjadian , Lee Yung Shih , Timothy Devos , Dorota Krochmalczyk , Serena Galli , Maria Bieniaszewska , Ilona Seferynska , Mary Frances McMullin , Anna Armatys , Adrianna Spalek , Joanna Waclaw , Mihnea Zdrenghea , Laurence Legros , François Girodon , Krzysztof Lewandowski , Anna Angona Figueras , Jan Samuelsson , Aitor Abuin Blanco , Pascale Cony-Makhoul , Angela Collins , Chloé James , Rajko Kusec , Marie Lauermannova , Maria Sol Noya , Malgorzata Skowronek , Lukasz Szukalski , Anna Szmigielska-Kaplon , Marielle Wondergem , Iryna Dudchenko , Joanna Gora Tybor , Kamel Laribi , Anna Kulikowska de Nalecz , Jean-Loup Demory , Katell Le Du , Sonja Zweegman , Carlos Besses Raebel , Radek Skoda , Stéphane Giraudier , Martin Griesshammer , Claire N Harrison , Jean-Christophe Ianotto

The ABNL-MARRO 001 study: a phase 1-2 study of randomly allocated active myeloid target compound combinations in MDS/MPN overlap syndromes.

BMC cancer

Avec: Tamara K Moyo , Jason H Mendler , Raphael Itzykson , Ashwin Kishtagari , Eric Solary , Adam C Seegmiller , Aaron T Gerds , Gregory D Ayers , Amy E Dezern , Aziz Nazha , Peter Valent , Arjan A van de Loosdrecht , Francesco Onida , Lisa Pleyer , Blanca Xicoy Cirici , Raoul Tibes , Klaus Geissler , Rami S Komrokji , Jing Zhang , Ulrich Germing , David P Steensma , Daniel H Wiseman , Michael Pfeilstöecker , Chiara Elena , Nicholas C P Cross , Jean-Jacques Kiladjian , Michael Luebbert , Ruben A Mesa , Guillermo Montalban-Bravo , Guillermo F Sanz , Uwe Platzbecker , Mrinal M Patnaik , Eric Padron , Valeria Santini , Pierre Fenaux , Michael R Savona , Auteur inconnu

Anemia in myelofibrosis: Current and emerging treatment options.

Critical reviews in oncology/hematology

Avec: Francesco Passamonti , Claire N Harrison , Ruben A Mesa , Jean-Jacques Kiladjian , Alessandro M Vannucchi , Srdan Verstovsek

Momelotinib versus danazol in symptomatic patients with anaemia and myelofibrosis (MOMENTUM): results from an international, double-blind, randomised, controlled, phase 3 study.

Lancet (London, England)

Avec: Srdan Verstovsek , Aaron T Gerds , Alessandro M Vannucchi , Haifa Kathrin Al-Ali , David Lavie , Andrew T Kuykendall , Sebastian Grosicki , Alessandra Iurlo , Yeow Tee Goh , Mihaela C Lazaroiu , Miklos Egyed , Maria Laura Fox , Donal McLornan , Andrew Perkins , Sung-Soo Yoon , Vikas Gupta , Jean-Jacques Kiladjian , Nikki Granacher , Sung-Eun Lee , Luminita Ocroteala , Francesco Passamonti , Claire N Harrison , Barbara J Klencke , Sunhee Ro , Rafe Donahue , Jun Kawashima , Ruben Mesa , Auteur inconnu

Clonal architecture evolution in Myeloproliferative Neoplasms: from a driver mutation to a complex heterogeneous mutational and phenotypic landscape.

Leukemia

Avec: Nabih Maslah , Lina Benajiba , Stephane Giraudier , Jean-Jacques Kiladjian , Bruno Cassinat

Matching-adjusted indirect comparison of the pelabresib-ruxolitinib combination vs JAKi monotherapy in myelofibrosis.

Blood advances

Avec: Vikas Gupta , John Mascarenhas , Marina Kremyanskaya , Raajit K Rampal , Moshe Talpaz , Jean-Jacques Kiladjian , Alessandro M Vannucchi , Srdan Verstovsek , Gozde Colak , Debarshi Dey , Claire Harrison

Advances in management of primary myelofibrosis and polycythaemia vera: Implications in clinical practice.

EJHaem

Avec: Shanti Amé , Fiorenza Barraco , Jean-Christophe Ianotto , Eric Jourdan , Jérôme Rey , Jean-François Viallard , Mathieu Wémeau , Jean-Jacques Kiladjian

Meaningful symptomatic change in patients with myelofibrosis from the SIMPLIFY studies.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

Avec: Stacie Hudgens , Srdan Verstovsek , Lysbeth Floden , Claire N Harrison , Jeanne Palmer , Vikas Gupta , Donal McLornan , Mary Frances McMulllin , Jean-Jacques Kiladjian , Lynda Foltz , Uwe Platzbecker , Maria Laura Fox , Adam J Mead , David M Ross , Stephen T Oh , Andrew A Perkins , Michael F Leahy , Samineh Deheshi , Rafe Donahue , Barbara J Klencke , Ruben A Mesa

Comparative clinical and molecular landscape of primary and secondary myelofibrosis: Superior performance of MIPSS70+ v2.0 over MYSEC-PM.

American journal of hematology

Avec: Matteo Guerra , Hélène Pasquer , Rafael Daltro de Oliveira , Juliette Soret-Dulphy , Nabih Maslah , Lin-Pierre Zhao , Clémence Marcault , Marine Cazaux , Nicolas Gauthier , Emmanuelle Verger , Nathalie Parquet , William Vainchenker , Emmanuel Raffoux , Stéphane Giraudier , Bruno Cassinat , Jean-Jacques Kiladjian , Lina Benajiba

Efficacy and safety of fedratinib in patients with myelofibrosis previously treated with ruxolitinib (FREEDOM2): results from a multicentre, open-label, randomised, controlled, phase 3 trial.

The Lancet. Haematology

Avec: Claire N Harrison , Ruben Mesa , Moshe Talpaz , Haifa Kathrin Al-Ali , Blanca Xicoy , Francesco Passamonti , Francesca Palandri , Giulia Benevolo , Alessandro Maria Vannucchi , Clemence Mediavilla , Alessandra Iurlo , InHo Kim , Shelonitda Rose , Patrick Brown , Christopher Hernandez , Jia Wang , Jean-Jacques Kiladjian

Synergistic effect of concurrent high molecular risk mutations and lower JAK2 mutant variant allele frequencies on prognosis in patients with myelofibrosis-insights from a multicenter study.

Leukemia

Avec: Yu-Hung Wang , Chao-Hung Wei , Chien-Chin Lin , Carmelo Gurnari , Hussein Awada , Lina Benajiba , Rafael Daltro de Oliveira , Juliette Soret-Dulphy , Bruno Cassinat , Andrius Zucenka , Adrián Mosquera Orgueira , Chang-Tsu Yuan , Sze-Hwei Lee , Chi-Yuan Yao , Kristian Gurashi , Hsin-An Hou , Kiran Batta , Manuel Mateo Pérez Encinas , Wen-Chien Chou , Jaroslaw P Maciejewski , Daniel H Wiseman , Jean-Jacques Kiladjian , Hwei-Fang Tien

Molecular profiling and risk classification of patients with myeloproliferative neoplasms and splanchnic vein thromboses.

Blood advances

Avec: Pierre-Edouard Debureaux , Bruno Cassinat , Juliette Soret-Dulphy , Barbara Mora , Emmanuelle Verger , Nabih Maslah , Aurelie Plessier , Pierre-Emmanuel Rautou , Isabelle Ollivier-Hourman , Victor De Ledinghen , Odile Goria , Christophe Bureau , Claudia Siracusa , Dominique Valla , Stephane Giraudier , Francesco Passamonti , Jean-Jacques Kiladjian

Characteristics and outcomes of patients with essential thrombocythemia or polycythemia vera diagnosed before 20 years of age: a systematic review.

Haematologica

Avec: Jean-Christophe Ianotto , Natalia Curto-Garcia , Marie Lauermanova , Deepti Radia , Jean-Jacques Kiladjian , Claire N Harrison

A First-in-Human Phase I Study of INVAC-1, an Optimized Human Telomerase DNA Vaccine in Patients with Advanced Solid Tumors.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Luis Teixeira , Jacques Medioni , Julie Garibal , Olivier Adotevi , Ludovic Doucet , Marie-Agnès Dragon Durey , Zineb Ghrieb , Jean-Jacques Kiladjian , Mara Brizard , Caroline Laheurte , Maria Wehbe , Elodie Pliquet , Marie Escande , Rémy Defrance , Stephane Culine , Stephane Oudard , Simon Wain-Hobson , Valérie Doppler , Thierry Huet , Pierre Langlade-Demoyen

Thromboembolic events in polycythemia vera.

Annals of hematology

Avec: Martin Griesshammer , Jean-Jacques Kiladjian , Carlos Besses

Emerging translational science discoveries, clonal approaches, and treatment trends in chronic myeloproliferative neoplasms.

Hematological oncology

Avec: Tariq I Mughal , Naveen Pemmaraju , Jerald P Radich , Michael W Deininger , Nicole Kucine , Jean-Jacques Kiladjian , Prithviraj Bose , Jason Gotlib , Peter Valent , Chih-Cheng Chen , Tiziano Barbui , Raajit Rampal , Srdan Verstovsek , Steffen Koschmieder , Giuseppe Saglio , Richard A Van Etten

Results from a First-in-Human Phase I Study of Siremadlin (HDM201) in Patients with Advanced Wild-Type TP53 Solid Tumors and Acute Leukemia.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Eytan M Stein , Daniel J DeAngelo , Jörg Chromik , Manik Chatterjee , Sebastian Bauer , Chia-Chi Lin , Cristina Suarez , Filip de Vos , Neeltje Steeghs , Philippe A Cassier , David Tai , Jean-Jacques Kiladjian , Noboru Yamamoto , Rogier Mous , Jordi Esteve , Hironobu Minami , Stephane Ferretti , Nelson Guerreiro , Christophe Meille , Rajkumar Radhakrishnan , Bernard Pereira , Luisa Mariconti , Ensar Halilovic , Claire Fabre , Cecilia Carpio

Favorable overall survival with imetelstat in relapsed/refractory myelofibrosis patients compared with real-world data.

Annals of hematology

Avec: Andrew T Kuykendall , Libo Sun , John Mascarenhas , Jean-Jacques Kiladjian , Alessandro M Vannucchi , Julia Wang , Qi Xia , Eugene Zhu , Faye Feller , Aleksandra Rizo , Jacqueline Bussolari , Ying Wan , Rami Komrokji

Retrospective analysis of pacritinib in patients with myelofibrosis and severe thrombocytopenia.

Haematologica

Avec: Srdan Verstovsek , Ruben Mesa , Moshe Talpaz , Jean-Jacques Kiladjian , Claire N Harrison , Stephen T Oh , Alessandro M Vannucchi , Raajit Rampal , Bart L Scott , Sarah A Buckley , Adam R Craig , Karisse Roman-Torres , John O Mascarenhas

Transient expansion of TP53 mutated clones in polycythemia vera patients treated with idasanutlin.

Blood advances

Avec: Bridget K Marcellino , Noushin Farnoud , Bruno Cassinat , Min Lu , Emanuelle Verger , Erin McGovern , Minal Patel , Juan Medina-Martinez , Max Fine Levine , Juanes E Arango Ossa , Yangyu Zhou , Heidi Kosiorek , Meenakshi Mehrotra , Jane Houldsworth , Amylou Dueck , Michael Rossi , John Mascarenhas , Jean-Jacques Kiladjian , Raajit K Rampal , Ronald Hoffman

Patient-reported Effects of Fedratinib, an Oral, Selective Inhibitor of Janus Kinase 2, on Myelofibrosis-related Symptoms and Health-related Quality of Life in the Randomized, Placebo-controlled, Phase III JAKARTA Trial.

HemaSphere

Avec: Ruben A Mesa , Nicolaas Schaap , Alessandro M Vannucchi , Jean-Jacques Kiladjian , Francesco Passamonti , Sonja Zweegman , Moshe Talpaz , Srdan Verstovsek , Shelonitda Rose , Pranav Abraham , Jennifer Lord-Bessen , Derek Tang , Shien Guo , Xiaomei Ye , Claire N Harrison

Randomized, Single-Blind, Multicenter Phase II Study of Two Doses of Imetelstat in Relapsed or Refractory Myelofibrosis.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Avec: John Mascarenhas , Rami S Komrokji , Francesca Palandri , Bruno Martino , Dietger Niederwieser , Andreas Reiter , Bart L Scott , Maria R Baer , Ronald Hoffman , Olatoyosi Odenike , Alessandro M Vannucchi , Jacqueline Bussolari , Eugene Zhu , Esther Rose , Laurie Sherman , Souria Dougherty , Libo Sun , Fei Huang , Ying Wan , Faye M Feller , Aleksandra Rizo , Jean-Jacques Kiladjian

Inferring the dynamics of mutated hematopoietic stem and progenitor cells induced by IFNα in myeloproliferative neoplasms.

Blood

Avec: Matthieu Mosca , Gurvan Hermange , Amandine Tisserand , Robert Noble , Christophe Marzac , Caroline Marty , Cécile Le Sueur , Hugo Campario , Gaëlle Vertenoeil , Mira El-Khoury , Cyril Catelain , Philippe Rameau , Cyril Gella , Julien Lenglet , Nicole Casadevall , Rémi Favier , Eric Solary , Bruno Cassinat , Jean-Jacques Kiladjian , Stefan N Constantinescu , Florence Pasquier , Michael E Hochberg , Hana Raslova , Jean-Luc Villeval , François Girodon , William Vainchenker , Paul-Henry Cournède , Isabelle Plo

Unmet clinical needs in the management of CALR-mutated essential thrombocythaemia: a consensus-based proposal from the European LeukemiaNet.

The Lancet. Haematology

Avec: Alberto Alvarez-Larrán , Emanuela Sant'Antonio , Claire Harrison , Jean-Jacques Kiladjian , Martin Griesshammer , Ruben Mesa , Jean Christophe Ianotto , Francesca Palandri , Juan Carlos Hernández-Boluda , Gunnar Birgegård , Jyoti Nangalia , Steffen Koschmieder , Elisa Rumi , Tiziano Barbui

Momelotinib in Myelofibrosis Patients With Thrombocytopenia: Post Hoc Analysis From Three Randomized Phase 3 Trials.

HemaSphere

Avec: Jean-Jacques Kiladjian , Alessandro M Vannucchi , Aaron T Gerds , Vikas Gupta , Srdan Verstovsek , Miklos Egyed , Uwe Platzbecker , Jiří Mayer , Sebastian Grosicki , Árpád Illés , Tomasz Woźny , Stephen T Oh , Donal McLornan , Ilya Kirgner , Sung-Soo Yoon , Claire N Harrison , Barbara Klencke , Mei Huang , Jun Kawashima , Ruben Mesa

Distinct clinico-molecular arterial and venous thrombosis scores for myeloproliferative neoplasms risk stratification.

Leukemia

Avec: Hélène Pasquer , Rafael Daltro de Oliveira , Loic Vasseur , Juliette Soret-Dulphy , Nabih Maslah , Lin-Pierre Zhao , Clémence Marcault , Marine Cazaux , Nicolas Gauthier , Emmanuelle Verger , Nathalie Parquet , William Vainchenker , Emmanuel Raffoux , Valérie Ugo , Damien Luque Paz , Lydia Roy , Wayne-Corentin Lambert , Jean-Christophe Ianotto , Eric Lippert , Stéphane Giraudier , Bruno Cassinat , Jean-Jacques Kiladjian , Lina Benajiba

Myeloproliferative neoplasms and splanchnic vein thrombosis: Contemporary diagnostic and therapeutic strategies.

American journal of hematology

Avec: Jean-Jacques Kiladjian , Bruno Cassinat

Symptomatic benefit of momelotinib in patients with myelofibrosis: Results from the SIMPLIFY phase III studies.

Cancer medicine

Avec: Ruben A Mesa , Stacie Hudgens , Lysbeth Floden , Claire N Harrison , Jeanne Palmer , Vikas Gupta , Donal P McLornan , Mary F McMullin , Jean-Jaques Kiladjian , Lynda Foltz , Uwe Platzbecker , M Laura Fox , Adam J Mead , David M Ross , Stephen T Oh , Andrew Perkins , Michael F Leahy , Samineh Deheshi , Rafe Donahue , Barbara J Klencke , Srdan Verstovsek

MANIFEST: Pelabresib in Combination With Ruxolitinib for Janus Kinase Inhibitor Treatment-Naïve Myelofibrosis.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Avec: John Mascarenhas , Marina Kremyanskaya , Andrea Patriarca , Francesca Palandri , Timothy Devos , Francesco Passamonti , Raajit K Rampal , Adam J Mead , Gabriella Hobbs , Joseph M Scandura , Moshe Talpaz , Nikki Granacher , Tim C P Somervaille , Ronald Hoffman , Marielle J Wondergem , Mohamed E Salama , Gozde Colak , Jike Cui , Jean-Jacques Kiladjian , Alessandro M Vannucchi , Srdan Verstovsek , Natalia Curto-García , Claire Harrison , Vikas Gupta

Réseau de co-auteurs

Jean-Jacques Kiladjian 90 collaborations

Srdan Verstovsek 30 collaborations

Alessandro M Vannucchi 26 collaborations

Claire N Harrison 23 collaborations

Bruno Cassinat 21 collaborations

Francesco Passamonti 17 collaborations

Claire Harrison 16 collaborations

Ruben Mesa 15 collaborations

Vikas Gupta 15 collaborations

Ruben A Mesa 14 collaborations

None None 13 collaborations

John Mascarenhas 13 collaborations

Moshe Talpaz 12 collaborations

Francesca Palandri 12 collaborations

Stephen T Oh 12 collaborations

Nabih Maslah 10 collaborations

Tiziano Barbui 10 collaborations

Uwe Platzbecker 10 collaborations

Emmanuelle Verger 9 collaborations

Steffen Koschmieder 9 collaborations

Aaron T Gerds 9 collaborations

Timothy Devos 9 collaborations

Miklos Egyed 8 collaborations

Stéphane Giraudier 8 collaborations

Valerio De Stefano 8 collaborations

Adam J Mead 8 collaborations

Lina Benajiba 8 collaborations

Jean-Christophe Ianotto 7 collaborations

Paola Guglielmelli 7 collaborations

Alessandra Iurlo 7 collaborations

Maria Laura Fox 7 collaborations

Donal McLornan 7 collaborations

Jun Kawashima 7 collaborations

Raajit K Rampal 7 collaborations

William Vainchenker 7 collaborations

Ronald Hoffman 7 collaborations

Martin Griesshammer 6 collaborations

Elisa Rumi 6 collaborations

Alessandro Maria Vannucchi 6 collaborations

Richard T Silver 6 collaborations

Haifa Kathrin Al-Ali 6 collaborations

Andrew Perkins 6 collaborations

Stephane Giraudier 5 collaborations

Sonja Zweegman 5 collaborations

Shelonitda Rose 5 collaborations

Sebastian Grosicki 5 collaborations

Rafe Donahue 5 collaborations

Mei Huang 5 collaborations

Isabelle Plo 5 collaborations

Giulia Benevolo 5 collaborations

Bart L Scott 5 collaborations

Prithviraj Bose 5 collaborations

Eric Jourdan 5 collaborations

David M Ross 5 collaborations

Lynda Foltz 5 collaborations

Juliette Soret-Dulphy 5 collaborations

Nicolaas Schaap 4 collaborations

David Lavie 4 collaborations

Andrew T Kuykendall 4 collaborations

Sung-Soo Yoon 4 collaborations

Barbara J Klencke 4 collaborations

Mary Frances McMullin 4 collaborations

Jeanne Palmer 4 collaborations

Karisse Roman-Torres 4 collaborations

Andrea Patriarca 4 collaborations

Blanca Xicoy Cirici 4 collaborations

Natalia Curto-Garcia 4 collaborations

Abdulraheem Yacoub 4 collaborations

Naveen Pemmaraju 4 collaborations

Fiorenza Barraco 4 collaborations

Jason Gotlib 4 collaborations

Rami S Komrokji 4 collaborations

Raajit Rampal 4 collaborations

Marina Kremyanskaya 4 collaborations

Carole B Miller 3 collaborations

Heinz Gisslinger 3 collaborations

Jiri Mayer 3 collaborations

Emmanuel Raffoux 3 collaborations

Marie Robin 3 collaborations

Gérard Socié 3 collaborations

Christine Chomienne 3 collaborations

Corentin Orvain 3 collaborations

Valérie Ugo 3 collaborations

Damien Luque Paz 3 collaborations

Mihaela C Lazaroiu 3 collaborations

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