Kristian W Pajtler

Affiliations

Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
Division of Pediatric Neurooncology (B062), German Cancer Research Center (DKFZ), Heidelberg, Germany.

Publications (79)

Transcriptional profiling of medulloblastoma with extensive nodularity (MBEN) reveals two clinically relevant tumor subsets with VSNL1 as potent prognostic marker.

Acta neuropathologica

Avec: Andrey Korshunov , Konstantin Okonechnikov , Felix Sahm , Marina Ryzhova , Damian Stichel , Daniel Schrimpf , David R Ghasemi , Kristian W Pajtler , Manila Antonelli , Vittoria Donofrio , Angela Mastronuzzi , Sabrina Rossi , Francesca Diomedi Camassei , Anna Maria Buccoliero , Christine Haberler , Irene Slavc , Sonika Dahiya , Belen Casalini , Philipp Sievers , Jochen Meyer , Ella Kumirova , Olga Zheludkova , Andrey Golanov , David T W Jones , Stefan M Pfister , Marcel Kool , Andreas von Deimling

Molecular characterization of histopathological ependymoma variants.

Acta neuropathologica

Avec: Julia E Neumann , Michael Spohn , Denise Obrecht , Martin Mynarek , Christian Thomas , Martin Hasselblatt , Mario M Dorostkar , Annika K Wefers , Stephan Frank , Camelia-Maria Monoranu , Arend Koch , Hendrik Witt , Marcel Kool , Kristian W Pajtler , Stefan Rutkowski , Markus Glatzel , Ulrich Schüller

Brainstem biopsy in pediatric diffuse intrinsic pontine glioma in the era of precision medicine: the INFORM study experience.

European journal of cancer (Oxford, England : 1990)

Avec: Elke Pfaff , Ahmed El Damaty , Gnana Prakash Balasubramanian , Mirjam Blattner-Johnson , Barbara C Worst , Sebastian Stark , Hendrik Witt , Kristian W Pajtler , Cornelis M van Tilburg , Ruth Witt , Till Milde , Martin Jakobs , Petra Fiesel , Michael C Frühwald , Pablo Hernáiz Driever , Ulrich W Thomale , Martin U Schuhmann , Markus Metzler , Konrad Bochennek , Thorsten Simon , Matthias Dürken , Michael Karremann , Stephanie Knirsch , Martin Ebinger , André O von Bueren , Torsten Pietsch , Christel Herold-Mende , David E Reuss , Karl Kiening , Peter Lichter , Angelika Eggert , Christof M Kramm , Stefan M Pfister , David T W Jones , Heidi Bächli , Olaf Witt

Diagnostics of pediatric supratentorial RELA ependymomas: integration of information from histopathology, genetics, DNA methylation and imaging.

Brain pathology (Zurich, Switzerland)

Avec: Mélanie Pagès , Kristian W Pajtler , Stéphanie Puget , David Castel , Nathalie Boddaert , Arnault Tauziède-Espariat , Stéphanie Picot , Marie-Anne Debily , Marcel Kool , David Capper , Christian Sainte-Rose , Fabrice Chrétien , Stefan M Pfister , Torsten Pietsch , Jacques Grill , Pascale Varlet , Felipe Andreiuolo

The genetic landscape of choroid plexus tumors in children and adults.

Neuro-oncology

Avec: Christian Thomas , Patrick Soschinski , Melissa Zwaig , Spyridon Oikonomopoulos , Konstantin Okonechnikov , Kristian W Pajtler , Martin Sill , Leonille Schweizer , Arend Koch , Julia Neumann , Ulrich Schüller , Felix Sahm , Laurèl Rauschenbach , Kathy Keyvani , Martin Proescholdt , Markus J Riemenschneider , Jochen Segewiß , Christian Ruckert , Oliver Grauer , Camelia-Maria Monoranu , Katrin Lamszus , Annarita Patrizi , Uwe Kordes , Reiner Siebert , Marcel Kool , Jiannis Ragoussis , William D Foulkes , Werner Paulus , Barbara Rivera , Martin Hasselblatt

Bioanalysis of selinexor in mouse plasma micro-samples utilizing UPLC-MS/MS.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Avec: Max Sauter , Kathrin I Foerster , Julia Benzel , Stefan Pfister , Kristian W Pajtler , Walter E Haefeli , Jürgen Burhenne

SIOP Ependymoma I: Final results, long-term follow-up, and molecular analysis of the trial cohort-A BIOMECA Consortium Study.

Neuro-oncology

Avec: Timothy A Ritzmann , Rebecca J Chapman , John-Paul Kilday , Nicola Thorp , Piergiorgio Modena , Robert A Dineen , Donald Macarthur , Conor Mallucci , Timothy Jaspan , Kristian W Pajtler , Marzia Giagnacovo , Thomas S Jacques , Simon M L Paine , David W Ellison , Eric Bouffet , Richard G Grundy

Analytical Performance Evaluation of New DESI Enhancements for Targeted Drug Quantification in Tissue Sections.

Pharmaceuticals (Basel, Switzerland)

Avec: Margaux Fresnais , Siwen Liang , Marius Breitkopf , Joshua Raoul Lindner , Emmanuelle Claude , Steven Pringle , Pavel A Levkin , Konstantin Demir , Julia Benzel , Julia Sundheimer , Britta Statz , Kristian W Pajtler , Stefan M Pfister , Walter E Haefeli , Jürgen Burhenne , Rémi Longuespée

Pediatric-type high-grade neuroepithelial tumors with CIC gene fusion share a common DNA methylation signature.

NPJ precision oncology

Avec: Philipp Sievers , Martin Sill , Daniel Schrimpf , Zied Abdullaev , Andrew M Donson , Jessica A Lake , Dennis Friedel , David Scheie , Olli Tynninen , Tuomas Rauramaa , Kaisa L Vepsäläinen , David Samuel , Rebecca Chapman , Richard G Grundy , Kristian W Pajtler , Arnault Tauziède-Espariat , Alice Métais , Pascale Varlet , Matija Snuderl , Thomas S Jacques , Kenneth Aldape , David E Reuss , Andrey Korshunov , Wolfgang Wick , Stefan M Pfister , Andreas von Deimling , Felix Sahm , David T W Jones

Molecular diagnostics enables detection of actionable targets: the Pediatric Targeted Therapy 2.0 registry.

European journal of cancer (Oxford, England : 1990)

Avec: Jonas Ecker , Florian Selt , Dominik Sturm , Martin Sill , Andrey Korshunov , Steffen Hirsch , David Capper , Nicola Dikow , Christian Sutter , Carina Müller , Romain Sigaud , Angelika Eggert , Thorsten Simon , Tim Niehues , Andreas von Deimling , Kristian W Pajtler , Cornelis M van Tilburg , David T W Jones , Felix Sahm , Stefan M Pfister , Olaf Witt , Till Milde

Rebound growth of BRAF mutant pediatric glioma cells after MAPKi withdrawal is associated with MAPK reactivation and secretion of microglia-recruiting cytokines.

Journal of neuro-oncology

Avec: Daniela Kocher , Lei Cao , Romain Guiho , Melanie Langhammer , Yun-Lu Lai , Pauline Becker , Hiba Hamdi , Dennis Friedel , Florian Selt , David Vonhören , Julia Zaman , Gintvile Valinciute , Sonja Herter , Daniel Picard , Johanna Rettenmeier , Kendra K Maass , Kristian W Pajtler , Marc Remke , Andreas von Deimling , Stefan Pusch , Stefan M Pfister , Ina Oehme , David T W Jones , Sebastian Halbach , Tilman Brummer , Juan Pedro Martinez-Barbera , Olaf Witt , Till Milde , Romain Sigaud

Second series by the Italian Association of Pediatric Hematology and Oncology of children and adolescents with intracranial ependymoma: an integrated molecular and clinical characterization with a long-term follow-up.

Neuro-oncology

Avec: Maura Massimino , Francesco Barretta , Piergiorgio Modena , Hendrik Witt , Simone Minasi , Stefan M Pfister , Kristian W Pajtler , Manila Antonelli , Lorenza Gandola , Maria Luisa Garrè , Daniele Bertin , Angela Mastronuzzi , Maurizio Mascarin , Lucia Quaglietta , Elisabetta Viscardi , Iacopo Sardi , Antonio Ruggiero , Bianca Pollo , Annamaria Buccoliero , Luna Boschetti , Elisabetta Schiavello , Luisa Chiapparini , Alessandra Erbetta , Isabella Morra , Marco Gessi , Vittoria Donofrio , Carlo Patriarca , Felice Giangaspero , Pascal Johann , Francesca Romana Buttarelli

Ultra high-risk PFA ependymoma is characterized by loss of chromosome 6q.

Neuro-oncology

Avec: Lorena V Baroni , Lakshmikirupa Sundaresan , Ayala Heled , Hallie Coltin , Kristian W Pajtler , Tong Lin , Thomas E Merchant , Roger McLendon , Claudia Faria , Molly Buntine , Christine L White , Stefan M Pfister , Mark R Gilbert , Terri S Armstrong , Eric Bouffet , Sachin Kumar , Michael D Taylor , Kenneth D Aldape , David W Ellison , Nicholas G Gottardo , Marcel Kool , Andrey Korshunov , Jordan R Hansford , Vijay Ramaswamy

Sarcoma classification by DNA methylation profiling.

Nature communications

Avec: Christian Koelsche , Daniel Schrimpf , Damian Stichel , Martin Sill , Felix Sahm , David E Reuss , Mirjam Blattner , Barbara Worst , Christoph E Heilig , Katja Beck , Peter Horak , Simon Kreutzfeldt , Elke Paff , Sebastian Stark , Pascal Johann , Florian Selt , Jonas Ecker , Dominik Sturm , Kristian W Pajtler , Annekathrin Reinhardt , Annika K Wefers , Philipp Sievers , Azadeh Ebrahimi , Abigail Suwala , Francisco Fernández-Klett , Belén Casalini , Andrey Korshunov , Volker Hovestadt , Felix K F Kommoss , Mark Kriegsmann , Matthias Schick , Melanie Bewerunge-Hudler , Till Milde , Olaf Witt , Andreas E Kulozik , Marcel Kool , Laura Romero-Pérez , Thomas G P Grünewald , Thomas Kirchner , Wolfgang Wick , Michael Platten , Andreas Unterberg , Matthias Uhl , Amir Abdollahi , Jürgen Debus , Burkhard Lehner , Christian Thomas , Martin Hasselblatt , Werner Paulus , Christian Hartmann , Ori Staszewski , Marco Prinz , Jürgen Hench , Stephan Frank , Yvonne M H Versleijen-Jonkers , Marije E Weidema , Thomas Mentzel , Klaus Griewank , Enrique de Álava , Juan Díaz Martín , Miguel A Idoate Gastearena , Kenneth Tou-En Chang , Sharon Yin Yee Low , Adrian Cuevas-Bourdier , Michel Mittelbronn , Martin Mynarek , Stefan Rutkowski , Ulrich Schüller , Viktor F Mautner , Jens Schittenhelm , Jonathan Serrano , Matija Snuderl , Reinhard Büttner , Thomas Klingebiel , Rolf Buslei , Manfred Gessler , Pieter Wesseling , Winand N M Dinjens , Sebastian Brandner , Zane Jaunmuktane , Iben Lyskjær , Peter Schirmacher , Albrecht Stenzinger , Benedikt Brors , Hanno Glimm , Christoph Heining , Oscar M Tirado , Miguel Sáinz-Jaspeado , Jaume Mora , Javier Alonso , Xavier Garcia Del Muro , Sebastian Moran , Manel Esteller , Jamal K Benhamida , Marc Ladanyi , Eva Wardelmann , Cristina Antonescu , Adrienne Flanagan , Uta Dirksen , Peter Hohenberger , Daniel Baumhoer , Wolfgang Hartmann , Christian Vokuhl , Uta Flucke , Iver Petersen , Gunhild Mechtersheimer , David Capper , David T W Jones , Stefan Fröhling , Stefan M Pfister , Andreas von Deimling

Single-Cell RNA-Seq Reveals Cellular Hierarchies and Impaired Developmental Trajectories in Pediatric Ependymoma.

Cancer cell

Avec: Johannes Gojo , Bernhard Englinger , Li Jiang , Jens M Hübner , McKenzie L Shaw , Olivia A Hack , Sibylle Madlener , Dominik Kirchhofer , Ilon Liu , Jason Pyrdol , Volker Hovestadt , Emanuele Mazzola , Nathan D Mathewson , Maria Trissal , Daniela Lötsch , Christian Dorfer , Christine Haberler , Angela Halfmann , Lisa Mayr , Andreas Peyrl , Rene Geyeregger , Benjamin Schwalm , Monica Mauermann , Kristian W Pajtler , Till Milde , Marni E Shore , Jack E Geduldig , Kristine Pelton , Thomas Czech , Orr Ashenberg , Kai W Wucherpfennig , Orit Rozenblatt-Rosen , Sanda Alexandrescu , Keith L Ligon , Stefan M Pfister , Aviv Regev , Irene Slavc , Walter Berger , Mario L Suvà , Marcel Kool , Mariella G Filbin

Investigating the Central Nervous System Disposition of Actinomycin D: Implementation and Evaluation of Cerebral Microdialysis and Brain Tissue Measurements Supported by UPLC-MS/MS Quantification.

Pharmaceutics

Avec: Julia Benzel , Gzona Bajraktari-Sylejmani , Philipp Uhl , Abigail Davis , Sreenath Nair , Stefan M Pfister , Walter E Haefeli , Johanna Weiss , Jürgen Burhenne , Kristian W Pajtler , Max Sauter

Serial assessment of measurable residual disease in medulloblastoma liquid biopsies.

Cancer cell

Avec: Anthony P Y Liu , Kyle S Smith , Rahul Kumar , Leena Paul , Laure Bihannic , Tong Lin , Kendra K Maass , Kristian W Pajtler , Murali Chintagumpala , Jack M Su , Eric Bouffet , Michael J Fisher , Sridharan Gururangan , Richard Cohn , Tim Hassall , Jordan R Hansford , Paul Klimo , Frederick A Boop , Clinton F Stewart , Julie H Harreld , Thomas E Merchant , Ruth G Tatevossian , Geoffrey Neale , Matthew Lear , Jeffery M Klco , Brent A Orr , David W Ellison , Richard J Gilbertson , Arzu Onar-Thomas , Amar Gajjar , Giles W Robinson , Paul A Northcott

Targeting fibroblast growth factor receptors to combat aggressive ependymoma.

Acta neuropathologica

Avec: Daniela Lötsch , Dominik Kirchhofer , Bernhard Englinger , Li Jiang , Konstantin Okonechnikov , Daniel Senfter , Anna Laemmerer , Lisa Gabler , Christine Pirker , Andrew M Donson , Peter Bannauer , Pia Korbel , Carola N Jaunecker , Jens-Martin Hübner , Lisa Mayr , Sibylle Madlener , Maria T Schmook , Gerda Ricken , Kendra Maaß , Michael Grusch , Klaus Holzmann , Bettina Grasl-Kraupp , Sabine Spiegl-Kreinecker , Jennifer Hsu , Christian Dorfer , Karl Rössler , Amedeo A Azizi , Nicholas K Foreman , Andreas Peyrl , Christine Haberler , Thomas Czech , Irene Slavc , Mariella G Filbin , Kristian W Pajtler , Marcel Kool , Walter Berger , Johannes Gojo

Clinically aggressive pediatric spinal ependymoma with novel MYC amplification demonstrates molecular and histopathologic similarity to newly described MYCN-amplified spinal ependymomas.

Acta neuropathologica communications

Avec: Margaret Shatara , Kathleen M Schieffer , Darren Klawinski , Diana L Thomas , Christopher R Pierson , Eric A Sribnick , Jeremy Jones , Diana P Rodriguez , Carol Deeg , Elizabeth Hamelberg , Stephanie LaHaye , Katherine E Miller , James Fitch , Benjamin Kelly , Kristen Leraas , Ruthann Pfau , Peter White , Vincent Magrini , Richard K Wilson , Elaine R Mardis , Mohamed S Abdelbaki , Jonathan L Finlay , Daniel R Boué , Catherine E Cottrell , David R Ghasemi , Kristian W Pajtler , Diana S Osorio

The treatment approach to pediatric non-rhabdomyosarcoma soft tissue sarcomas: a critical review from the INternational Soft Tissue SaRcoma ConsorTium.

European journal of cancer (Oxford, England : 1990)

Avec: Andrea Ferrari , Daniel Orbach , Monika Sparber-Sauer , David O Walterhouse , Kristian W Pajtler , William H Meyer , Sheri L Spunt , Aaron R Weiss

The first-in-class ERK inhibitor ulixertinib shows promising activity in mitogen-activated protein kinase (MAPK)-driven pediatric low-grade glioma models.

Neuro-oncology

Avec: Romain Sigaud , Lisa Rösch , Charlotte Gatzweiler , Julia Benzel , Laura von Soosten , Heike Peterziel , Florian Selt , Sara Najafi , Simay Ayhan , Xenia F Gerloff , Nina Hofmann , Isabel Büdenbender , Lukas Schmitt , Kathrin I Foerster , Jürgen Burhenne , Walter E Haefeli , Andrey Korshunov , Felix Sahm , Cornelis M van Tilburg , David T W Jones , Stefan M Pfister , Deborah Knoerzer , Brent L Kreider , Max Sauter , Kristian W Pajtler , Marc Zuckermann , Ina Oehme , Olaf Witt , Till Milde

Radiotherapy for Recurrent Medulloblastoma in Children and Adolescents: Survival after Re-Irradiation and First-Time Irradiation.

Cancers

Avec: Jonas E Adolph , Gudrun Fleischhack , Sebastian Tschirner , Lydia Rink , Christine Dittes , Ruth Mikasch , Philipp Dammann , Martin Mynarek , Denise Obrecht-Sturm , Stefan Rutkowski , Brigitte Bison , Monika Warmuth-Metz , Torsten Pietsch , Stefan M Pfister , Kristian W Pajtler , Till Milde , Rolf-Dieter Kortmann , Stefan Dietzsch , Beate Timmermann , Stephan Tippelt , Auteur inconnu

Genotype-phenotype associations within the Li-Fraumeni spectrum: a report from the German Registry.

Journal of hematology & oncology

Avec: Judith Penkert , Farina J Strüwe , Christina M Dutzmann , Beate B Doergeloh , Emilie Montellier , Claire Freycon , Myriam Keymling , Heinz-Peter Schlemmer , Birte Sänger , Beatrice Hoffmann , Tanja Gerasimov , Claudia Blattmann , Sebastian Fetscher , Michael Frühwald , Simone Hettmer , Uwe Kordes , Vita Ridola , Sabine Kroiss Benninger , Angela Mastronuzzi , Sarah Schott , Juliane Nees , Aram Prokop , Antje Redlich , Markus G Seidel , Stefanie Zimmermann , Kristian W Pajtler , Stefan M Pfister , Pierre Hainaut , Christian P Kratz

Response assessment in paediatric intracranial ependymoma: recommendations from the Response Assessment in Pediatric Neuro-Oncology (RAPNO) working group.

The Lancet. Oncology

Avec: Holly B Lindsay , Maura Massimino , Shivaram Avula , Stavros Stivaros , Richard Grundy , Katie Metrock , Aashim Bhatia , Ana Fernández-Teijeiro , Luisa Chiapparini , Jeffrey Bennett , Karen Wright , Lindsey M Hoffman , Amy Smith , Kristian W Pajtler , Tina Young Poussaint , Katherine E Warren , Nicholas K Foreman , David M Mirsky

Glioneuronal tumor with ATRX alteration, kinase fusion and anaplastic features (GTAKA): a molecularly distinct brain tumor type with recurrent NTRK gene fusions.

Acta neuropathologica

Avec: Henri Bogumil , Martin Sill , Daniel Schrimpf , Britta Ismer , Christina Blume , Ramin Rahmanzade , Felix Hinz , Asan Cherkezov , Rouzbeh Banan , Dennis Friedel , David E Reuss , Florian Selt , Jonas Ecker , Till Milde , Kristian W Pajtler , Jens Schittenhelm , Jürgen Hench , Stephan Frank , Henning B Boldt , Bjarne Winther Kristensen , David Scheie , Linea C Melchior , Viola Olesen , Astrid Sehested , Daniel R Boué , Zied Abdullaev , Laveniya Satgunaseelan , Ina Kurth , Annekatrin Seidlitz , Christine L White , Ho-Keung Ng , Zhi-Feng Shi , Christine Haberler , Martina Deckert , Marco Timmer , Roland Goldbrunner , Arnault Tauziède-Espariat , Pascale Varlet , Sebastian Brandner , Sanda Alexandrescu , Matija Snuderl , Kenneth Aldape , Andrey Korshunov , Olaf Witt , Christel Herold-Mende , Andreas Unterberg , Wolfgang Wick , Stefan M Pfister , Andreas von Deimling , David T W Jones , Felix Sahm , Philipp Sievers

Mapping pediatric brain tumors to their origins in the developing cerebellum.

Neuro-oncology

Avec: Konstantin Okonechnikov , Piyush Joshi , Mari Sepp , Kevin Leiss , Ioannis Sarropoulos , Florent Murat , Martin Sill , Pengbo Beck , Kenneth Chun-Ho Chan , Andrey Korshunov , Felix Sah , Maximilian Y Deng , Dominik Sturm , John DeSisto , Andrew M Donson , Nicholas K Foreman , Adam L Green , Giles Robinson , Brent A Orr , Qingsong Gao , Emily Darrow , Jennifer L Hadley , Paul A Northcott , Johannes Gojo , Daisuke Kawauchi , Volker Hovestadt , Mariella G Filbin , Andreas von Deimling , Marc Zuckermann , Kristian W Pajtler , Marcel Kool , David T W Jones , Natalie Jäger , Lena M Kutscher , Henrik Kaessmann , Stefan M Pfister

Radiotherapy and long-term sequelae in pediatric patients with parameningeal rhabdomyosarcoma: Results of two Cooperative Weichteilsarkom Studiengruppe (CWS) trials and one registry.

Pediatric blood & cancer

Avec: Monika Sparber-Sauer , Maximilian Dietzschold , Anton Schönstein , Amadeus Heinz , Christian Vokuhl , Kristian W Pajtler , Semi Harrabi , Yi-Lan Lin , Thekla von Kalle , Rudolf Hagen , Ruth Ladenstein , Bernarda Kazanowska , Gustaf Ljungman , Thomas Klingebiel , Martin Ebinger , Ewa Koscielniak , Marc Münter , Beate Timmermann , Auteur inconnu

Molecular characteristics and improved survival prediction in a cohort of 2023 ependymomas.

Acta neuropathologica

Avec: Lara C Pohl , Maximilian Leitheiser , Denise Obrecht , Leonille Schweizer , Annika K Wefers , Alicia Eckhardt , Mark Raffeld , Dominik Sturm , Kristian W Pajtler , Stefan Rutkowski , Kohei Fukuoka , Koichi Ichimura , Michael Bockmayr , Ulrich Schüller

Germline Elongator mutations in Sonic Hedgehog medulloblastoma.

Nature

Avec: Sebastian M Waszak , Giles W Robinson , Brian L Gudenas , Kyle S Smith , Antoine Forget , Marija Kojic , Jesus Garcia-Lopez , Jennifer Hadley , Kayla V Hamilton , Emilie Indersie , Ivo Buchhalter , Jules Kerssemakers , Natalie Jäger , Tanvi Sharma , Tobias Rausch , Marcel Kool , Dominik Sturm , David T W Jones , Aksana Vasilyeva , Ruth G Tatevossian , Geoffrey Neale , Bérangère Lombard , Damarys Loew , Joy Nakitandwe , Michael Rusch , Daniel C Bowers , Anne Bendel , Sonia Partap , Murali Chintagumpala , John Crawford , Nicholas G Gottardo , Amy Smith , Christelle Dufour , Stefan Rutkowski , Tone Eggen , Finn Wesenberg , Kristina Kjaerheim , Maria Feychting , Birgitta Lannering , Joachim Schüz , Christoffer Johansen , Tina V Andersen , Martin Röösli , Claudia E Kuehni , Michael Grotzer , Marc Remke , Stéphanie Puget , Kristian W Pajtler , Till Milde , Olaf Witt , Marina Ryzhova , Andrey Korshunov , Brent A Orr , David W Ellison , Laurence Brugieres , Peter Lichter , Kim E Nichols , Amar Gajjar , Brandon J Wainwright , Olivier Ayrault , Jan O Korbel , Paul A Northcott , Stefan M Pfister

INFORM2 NivEnt: The first trial of the INFORM2 biomarker driven phase I/II trial series: the combination of nivolumab and entinostat in children and adolescents with refractory high-risk malignancies.

BMC cancer

Avec: Cornelis M van Tilburg , Ruth Witt , Melanie Heiss , Kristian W Pajtler , Christoph Plass , Isabel Poschke , Michael Platten , Inga Harting , Oliver Sedlaczek , Angelika Freitag , David Meyrath , Lenka Taylor , Gnana Prakash Balasubramanian , Natalie Jäger , Elke Pfaff , Barbara C Jones , Till Milde , Stefan M Pfister , David T W Jones , Annette Kopp-Schneider , Olaf Witt

[Update on Li-Fraumeni syndrome].

Der Pathologe

Avec: C M Dutzmann , J Vogel , C P Kratz , K W Pajtler , S M Pfister , B B Dörgeloh

EANO-EURACAN clinical practice guideline for diagnosis, treatment, and follow-up of post-pubertal and adult patients with medulloblastoma.

The Lancet. Oncology

Avec: Enrico Franceschi , Silvia Hofer , Alba A Brandes , Didier Frappaz , Rolf-Dieter Kortmann , Jacoline Bromberg , Volodia Dangouloff-Ros , Nathalie Boddaert , Elke Hattingen , Benedikt Wiestler , Steven C Clifford , Dominique Figarella-Branger , Felice Giangaspero , Christine Haberler , Torsten Pietsch , Kristian W Pajtler , Stefan M Pfister , Raphael Guzman , Walter Stummer , Stephanie E Combs , Clemens Seidel , Dagmar Beier , Martin G McCabe , Michael Grotzer , Florence Laigle-Donadey , Ana S Guerreiro Stücklin , Ahmed Idbaih , Matthias Preusser , Martin van den Bent , Michael Weller , Peter Hau

Evaluation of Storage Tubes for Combined Analysis of Circulating Nucleic Acids in Liquid Biopsies.

International journal of molecular sciences

Avec: Aoife Ward Gahlawat , Judith Lenhardt , Tania Witte , Denise Keitel , Anna Kaufhold , Kendra K Maass , Kristian W Pajtler , Christof Sohn , Sarah Schott

Newly Diagnosed Metastatic Intracranial Ependymoma in Children: Frequency, Molecular Characteristics, Treatment, and Outcome in the Prospective HIT Series.

The oncologist

Avec: Martin Benesch , Martin Mynarek , Hendrik Witt , Monika Warmuth-Metz , Torsten Pietsch , Brigitte Bison , Stefan M Pfister , Kristian W Pajtler , Marcel Kool , Ulrich Schüller , Klaus Pietschmann , Björn-Ole Juhnke , Stephan Tippelt , Gudrun Fleischhack , Irene Schmid , Christof M Kramm , Peter Vorwerk , Andreas Beilken , Carl Friedrich Classen , Pablo Hernáiz Driever , Gabriele Kropshofer , Thomas Imschweiler , Andreas Lemmer , Rolf-Dieter Kortmann , Stefan Rutkowski , Katja von Hoff

YAP1 subgroup supratentorial ependymoma requires TEAD and nuclear factor I-mediated transcriptional programmes for tumorigenesis.

Nature communications

Avec: Kristian W Pajtler , Yiju Wei , Konstantin Okonechnikov , Patricia B G Silva , Mikaella Vouri , Lei Zhang , Sebastian Brabetz , Laura Sieber , Melissa Gulley , Monika Mauermann , Tatjana Wedig , Norman Mack , Yuka Imamura Kawasawa , Tanvi Sharma , Marc Zuckermann , Felipe Andreiuolo , Eric Holland , Kendra Maass , Huiqin Körkel-Qu , Hai-Kun Liu , Felix Sahm , David Capper , Jens Bunt , Linda J Richards , David T W Jones , Andrey Korshunov , Lukas Chavez , Peter Lichter , Mikio Hoshino , Stefan M Pfister , Marcel Kool , Wei Li , Daisuke Kawauchi

Cerebrospinal Fluid Penetration and Combination Therapy of Entrectinib for Disseminated

Journal of personalized medicine

Avec: Lisa Mayr , Armin S Guntner , Sibylle Madlener , Maria T Schmook , Andreas Peyrl , Amedeo A Azizi , Karin Dieckmann , Dominik Reisinger , Natalia M Stepien , Kathrin Schramm , Anna Laemmerer , David T W Jones , Jonas Ecker , Felix Sahm , Till Milde , Kristian W Pajtler , Mirjam Blattner-Johnson , Miroslav Strbac , Christian Dorfer , Thomas Czech , Dominik Kirchhofer , Lisa Gabler , Walter Berger , Christine Haberler , Leonhard Müllauer , Wolfgang Buchberger , Irene Slavc , Daniela Lötsch-Gojo , Johannes Gojo

Rapid MALDI-MS Assays for Drug Quantification in Biological Matrices: Lessons Learned, New Developments, and Future Perspectives.

Molecules (Basel, Switzerland)

Avec: Margaux Fresnais , Esra Yildirim , Seda Karabulut , Dirk Jäger , Inka Zörnig , Julia Benzel , Kristian W Pajtler , Stefan M Pfister , Jürgen Burhenne , Walter E Haefeli , Rémi Longuespée

SMARCB1-deficient and SMARCA4-deficient Malignant Brain Tumors With Complex Copy Number Alterations and TP53 Mutations May Represent the First Clinical Manifestation of Li-Fraumeni Syndrome.

The American journal of surgical pathology

Avec: Martin Hasselblatt , Christian Thomas , Aniello Federico , Karolina Nemes , Pascal D Johann , Brigitte Bison , Susanne Bens , Sonja Dahlum , Uwe Kordes , Antje Redlich , Lienhard Lessel , Kristian W Pajtler , Christian Mawrin , Ulrich Schüller , Kay Nolte , Christof M Kramm , Felix Hinz , Felix Sahm , Caterina Giannini , Judith Penkert , Christian P Kratz , Stefan M Pfister , Reiner Siebert , Werner Paulus , Marcel Kool , Michael C Frühwald

Clinical outcome of pediatric medulloblastoma patients with Li-Fraumeni syndrome.

Neuro-oncology

Avec: Anna S Kolodziejczak , Lea Guerrini-Rousseau , Julien Masliah Planchon , Jonas Ecker , Florian Selt , Martin Mynarek , Denise Obrecht , Martin Sill , Robert J Autry , Eric Stutheit-Zhao , Steffen Hirsch , Elsa Amouyal , Christelle Dufour , Olivier Ayrault , Jacob Torrejon , Sebastian M Waszak , Vijay Ramaswamy , Virve Pentikainen , Haci Ahmet Demir , Steven C Clifford , Ed C Schwalbe , Luca Massimi , Matija Snuderl , Kristyn Galbraith , Matthias A Karajannis , Katherine Hill , Bryan K Li , Mike Walsh , Christine L White , Shelagh Redmond , Loizou Loizos , Marcus Jakob , Uwe R Kordes , Irene Schmid , Julia Hauer , Claudia Blattmann , Maria Filippidou , Gianluca Piccolo , Wolfram Scheurlen , Ahmed Farrag , Kerstin Grund , Christian Sutter , Torsten Pietsch , Stephan Frank , Denis M Schewe , David Malkin , Myriam Ben-Arush , Astrid Sehested , Tai-Tong Wong , Kuo-Sheng Wu , Yen-Lin Liu , Fernando Carceller , Sabine Mueller , Schuyler Stoller , Michael D Taylor , Uri Tabori , Eric Bouffet , Marcel Kool , Felix Sahm , Andreas von Deimling , Andrey Korshunov , Katja von Hoff , Christian P Kratz , Dominik Sturm , David T W Jones , Stefan Rutkowski , Cornelis M van Tilburg , Olaf Witt , Gaëlle Bougeard , Kristian W Pajtler , Stefan M Pfister , Franck Bourdeaut , Till Milde

Outcome of Children and Adolescents With Relapsed/Refractory/Progressive Malignancies Treated With Molecularly Informed Targeted Drugs in the Pediatric Precision Oncology Registry INFORM.

JCO precision oncology

Avec: Anna-Elisa Heipertz , Kristian W Pajtler , Elke Pfaff , Kathrin Schramm , Mirjam Blattner-Johnson , Till Milde , Barbara C Jones , Cecilia Zuliani , Caroline Hutter , Olli Lohi , Antonis Kattamis , Iwona Dachowska-Kalwak , Anna Nilsson , Nicolas U Gerber , Karin P S Langenberg , Bianca Goemans , C Michel Zwaan , Jan J Molenaar , Natalie Jäger , Uta Dirksen , Ruth Witt , Stefan M Pfister , David T W Jones , Annette Kopp-Schneider , Olaf Witt , Cornelis M van Tilburg

Molecular analysis of cancer genomes in children with Lynch syndrome: Exploring causal associations.

International journal of cancer

Avec: Dilys D Weijers , Steffen Hirsch , Jette J Bakhuizen , Nienke van Engelen , Lennart A Kester , Mariëtte E G Kranendonk , Laura S Hiemcke-Jiwa , Evelien de Vos-Kerkhof , Jan L C Loeffen , Robert J Autry , Kristian W Pajtler , Natalie Jäger , Marjolijn C J Jongmans , Roland P Kuiper

Cerebrospinal fluid cfDNA sequencing for classification of central nervous system glioma.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Florian Iser , Felix Hinz , Dirk C Hoffmann , Niklas Grassl , Cansu Güngör , Jochen Meyer , Laura Dörner , Lea Hofmann , Vanessa Kelbch , Kirsten Göbel , Mustafa Ahmed Mahmutoglu , Phillipp Vollmuth , Areeba Patel , Duy Nguyen , Leon D Kaulen , Iris Mildenberger , Katharina Sahm , Kendra Maaß , Kristian W Pajtler , Ganesh M Shankar , Markus Weiler , Brigitte Wildemann , Frank Winkler , Andreas von Deimling , Michael Platten , Wolfgang Wick , Felix Sahm , Tobias Kessler

Update on surveillance for Wilms tumor and hepatoblastoma in Beckwith-Wiedemann Syndrome and other predisposition syndromes.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Jennifer M Kalish , Kerri D Becktell , Gaëlle Bougeard , Garrett M Brodeur , Lisa R Diller , Andrea S Doria , Jordan R Hansford , Steven D Klein , Wendy K Kohlmann , Christian P Kratz , Suzanne P MacFarland , Kristian W Pajtler , Surya P Rednam , Jaclyn Schienda , Lisa J States , Anita Villani , Rosanna Weksberg , Kristin Zelley , Gail E Tomlinson , Jack J Brzezinski

Central nervous system tumors in adolescents and young adults: A Society for Neuro-Oncology consensus review on diagnosis, management, and future directions.

Neuro-oncology

Avec: Mary Jane Lim-Fat , Julie Bennett , Quinn Ostrom , Mehdi Touat , Enrico Franceschi , Jessica Schulte , Ranjit S Bindra , Jason Fangusaro , Girish Dhall , James Nicholson , Sadhana Jackson , Tom Belle Davidson , Gabriele Calaminus , Giles Robinson , James R Whittle , Peter Hau , Vijay Ramaswamy , Kristian W Pajtler , Roberta Rudà , Nicholas K Foreman , Shawn L Hervey-Jumper , Sunit Das , Peter Dirks , Wenya Linda Bi , Annie Huang , Thomas E Merchant , Maryam Fouladi , Kenneth Aldape , Martin J Van den Bent , Roger J Packer , Julie J Miller , David A Reardon , Susan M Chang , Daphne Haas-Kogan , Uri Tabori , Cynthia Hawkins , Michelle Monje , Patrick Y Wen , Eric Bouffet , Kee Kiat Yeo

Comparison of tumor-associated YAP1 fusions identifies a recurrent set of functions critical for oncogenesis.

Genes & development

Avec: Frank Szulzewsky , Sonali Arora , Pia Hoellerbauer , Claire King , Erica Nathan , Marina Chan , Patrick J Cimino , Tatsuya Ozawa , Daisuke Kawauchi , Kristian W Pajtler , Richard J Gilbertson , Patrick J Paddison , Valeri Vasioukhin , Taranjit S Gujral , Eric C Holland

Cancer predisposition in pediatric neuro-oncology-practical approaches and ethical considerations.

Neuro-oncology practice

Avec: Steffen Hirsch , Nicola Dikow , Stefan M Pfister , Kristian W Pajtler

Cross-Species Genomics Reveals Oncogenic Dependencies in ZFTA/C11orf95 Fusion-Positive Supratentorial Ependymomas.

Cancer discovery

Avec: Tuyu Zheng , David R Ghasemi , Konstantin Okonechnikov , Andrey Korshunov , Martin Sill , Kendra K Maass , Patricia Benites Goncalves da Silva , Marina Ryzhova , Johannes Gojo , Damian Stichel , Amir Arabzade , Robert Kupp , Julia Benzel , Shinichiro Taya , Toma Adachi , Ryo Shiraishi , Nicolas U Gerber , Dominik Sturm , Jonas Ecker , Philipp Sievers , Florian Selt , Rebecca Chapman , Christine Haberler , Dominique Figarella-Branger , Guido Reifenberger , Gudrun Fleischhack , Stefan Rutkowski , Andrew M Donson , Vijay Ramaswamy , David Capper , David W Ellison , Christel C Herold-Mende , Ulrich Schüller , Sebastian Brandner , Pablo Hernáiz Driever , Johan M Kros , Matija Snuderl , Till Milde , Richard G Grundy , Mikio Hoshino , Stephen C Mack , Richard J Gilbertson , David T W Jones , Marcel Kool , Andreas von Deimling , Stefan M Pfister , Felix Sahm , Daisuke Kawauchi , Kristian W Pajtler

ZFTA-RELA Dictates Oncogenic Transcriptional Programs to Drive Aggressive Supratentorial Ependymoma.

Cancer discovery

Avec: Amir Arabzade , Yanhua Zhao , Srinidhi Varadharajan , Hsiao-Chi Chen , Selin Jessa , Bryan Rivas , Austin J Stuckert , Minerva Solis , Alisha Kardian , Dana Tlais , Brian J Golbourn , Ann-Catherine J Stanton , Yuen San Chan , Calla Olson , Kristen L Karlin , Kathleen Kong , Robert Kupp , Baoli Hu , Sarah G Injac , Madeline Ngo , Peter R Wang , Luz A De León , Felix Sahm , Daisuke Kawauchi , Stefan M Pfister , Charles Y Lin , H Courtney Hodges , Irtisha Singh , Thomas F Westbrook , Murali M Chintagumpala , Susan M Blaney , Donald W Parsons , Kristian W Pajtler , Sameer Agnihotri , Richard J Gilbertson , Joanna Yi , Nada Jabado , Claudia L Kleinman , Kelsey C Bertrand , Benjamin Deneen , Stephen C Mack

From Sampling to Sequencing: A Liquid Biopsy Pre-Analytic Workflow to Maximize Multi-Layer Genomic Information from a Single Tube.

Cancers

Avec: Kendra K Maass , Paulina S Schad , Agnes M E Finster , Pitithat Puranachot , Fabian Rosing , Tatjana Wedig , Nathalie Schwarz , Natalie Stumpf , Stefan M Pfister , Kristian W Pajtler

PATZ1 fusions define a novel molecularly distinct neuroepithelial tumor entity with a broad histological spectrum.

Acta neuropathologica

Avec: Karam T Alhalabi , Damian Stichel , Philipp Sievers , Heike Peterziel , Alexander C Sommerkamp , Dominik Sturm , Andrea Wittmann , Martin Sill , Natalie Jäger , Pengbo Beck , Kristian W Pajtler , Matija Snuderl , George Jour , Michael Delorenzo , Allison M Martin , Adam Levy , Nagma Dalvi , Jordan R Hansford , Nicholas G Gottardo , Emmanuelle Uro-Coste , Claude-Alain Maurage , Catherine Godfraind , Fanny Vandenbos , Torsten Pietsch , Christof Kramm , Maria Filippidou , Antonis Kattamis , Chris Jones , Ingrid Øra , Torben Stamm Mikkelsen , Michal Zapotocky , David Sumerauer , David Scheie , Martin McCabe , Pieter Wesseling , Bastiaan B J Tops , Mariëtte E G Kranendonk , Matthias A Karajannis , Nancy Bouvier , Elli Papaemmanuil , Hildegard Dohmen , Till Acker , Katja von Hoff , Simone Schmid , Evelina Miele , Katharina Filipski , Lidija Kitanovski , Lenka Krskova , Johannes Gojo , Christine Haberler , Frank Alvaro , Jonas Ecker , Florian Selt , Till Milde , Olaf Witt , Ina Oehme , Marcel Kool , Andreas von Deimling , Andrey Korshunov , Stefan M Pfister , Felix Sahm , David T W Jones

How we treat medulloblastoma in adults.

ESMO open

Avec: E Franceschi , C Seidel , F Sahm , K W Pajtler , P Hau

Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors.

Acta neuropathologica

Avec: Philipp Sievers , Sophie C Henneken , Christina Blume , Martin Sill , Daniel Schrimpf , Damian Stichel , Konstantin Okonechnikov , David E Reuss , Julia Benzel , Kendra K Maaß , Marcel Kool , Dominik Sturm , Tuyu Zheng , David R Ghasemi , Patricia Kohlhof-Meinecke , Ofelia Cruz , Mariona Suñol , Cinzia Lavarino , Viktoria Ruf , Henning B Boldt , Mélanie Pagès , Celso Pouget , Leonille Schweizer , Mariëtte E G Kranendonk , Noreen Akhtar , Stephanie Bunkowski , Christine Stadelmann , Ulrich Schüller , Wolf C Mueller , Hildegard Dohmen , Till Acker , Patrick N Harter , Christian Mawrin , Rudi Beschorner , Sebastian Brandner , Matija Snuderl , Zied Abdullaev , Kenneth Aldape , Mark R Gilbert , Terri S Armstrong , David W Ellison , David Capper , Koichi Ichimura , Guido Reifenberger , Richard G Grundy , Nada Jabado , Lenka Krskova , Michal Zapotocky , Ales Vicha , Pascale Varlet , Pieter Wesseling , Stefan Rutkowski , Andrey Korshunov , Wolfgang Wick , Stefan M Pfister , David T W Jones , Andreas von Deimling , Kristian W Pajtler , Felix Sahm

Important Requirements for the Selection of Internal Standards during the Development of Desorption/Ionization Assays for Drug Quantification in Biological Matrices-A Practical Example.

Molecules (Basel, Switzerland)

Avec: Margaux Fresnais , Seda Karabulut , Yasmin Abou Zeed , Johannes Ungermann , Julia Benzel , Kristian W Pajtler , Stefan M Pfister , Walter E Haefeli , Jürgen Burhenne , Rémi Longuespée

The Current Landscape of Targeted Clinical Trials in Non-WNT/Non-SHH Medulloblastoma.

Cancers

Avec: David R Ghasemi , Gudrun Fleischhack , Till Milde , Kristian W Pajtler

Compartments in medulloblastoma with extensive nodularity are connected through differentiation along the granular precursor lineage.

Nature communications

Avec: David R Ghasemi , Konstantin Okonechnikov , Anne Rademacher , Stephan Tirier , Kendra K Maass , Hanna Schumacher , Piyush Joshi , Maxwell P Gold , Julia Sundheimer , Britta Statz , Ahmet S Rifaioglu , Katharina Bauer , Sabrina Schumacher , Michele Bortolomeazzi , Felice Giangaspero , Kati J Ernst , Steven C Clifford , Julio Saez-Rodriguez , David T W Jones , Daisuke Kawauchi , Ernest Fraenkel , Jan-Philipp Mallm , Karsten Rippe , Andrey Korshunov , Stefan M Pfister , Kristian W Pajtler

Clinically relevant molecular hallmarks of PFA ependymomas display intratumoral heterogeneity and correlate with tumor morphology.

Acta neuropathologica

Avec: Swenja Gödicke , Catena Kresbach , Max Ehlert , Denise Obrecht , Lea Altendorf , Karoline Hack , Katja von Hoff , Helena Carén , Viktoria Melcher , Kornelius Kerl , Bernhard Englinger , Mariella Filbin , Kristian W Pajtler , Johannes Gojo , Torsten Pietsch , Stefan Rutkowski , Ulrich Schüller

PTPRD and CNTNAP2 as markers of tumor aggressiveness in oligodendrogliomas.

Scientific reports

Avec: Kirsi J Rautajoki , Serafiina Jaatinen , Aliisa M Tiihonen , Matti Annala , Elisa M Vuorinen , Anni Kivinen , Minna J Rauhala , Kendra K Maass , Kristian W Pajtler , Olli Yli-Harja , Pauli Helén , Joonas Haapasalo , Hannu Haapasalo , Wei Zhang , Matti Nykter

Optimizing biomarkers for accurate ependymoma diagnosis, prognostication, and stratification within International Clinical Trials: A BIOMECA study.

Neuro-oncology

Avec: Rebecca J Chapman , David R Ghasemi , Felipe Andreiuolo , Valentina Zschernack , Arnault Tauziede Espariat , Francesca R Buttarelli , Felice Giangaspero , Jacques Grill , Christine Haberler , Simon M L Paine , Ian Scott , Thomas S Jacques , Martin Sill , Stefan Pfister , John-Paul Kilday , Pierre Leblond , Maura Massimino , Hendrik Witt , Piergiorgio Modena , Pascale Varlet , Torsten Pietsch , Richard G Grundy , Kristian W Pajtler , Timothy A Ritzmann

Key Pharmacokinetic Parameters of 74 Pediatric Anticancer Drugs Providing Assistance in Preclinical Studies.

Clinical pharmacology and therapeutics

Avec: Nora Jamaladdin , Romain Sigaud , Daniela Kocher , Anna S Kolodziejczak , Leo F Nonnenbroich , Jonas Ecker , Diren Usta , Julia Benzel , Heike Peterziel , Kristian W Pajtler , Cornelis M van Tilburg , Ina Oehme , Olaf Witt , Till Milde

Significant increase of high-risk chromosome 1q gain and 6q loss at recurrence in posterior fossa group A ependymoma: A multicenter study.

Neuro-oncology

Avec: Andrew M Donson , Kelsey C Bertrand , Kent A Riemondy , Dexiang Gao , Yonghua Zhuang , Bridget Sanford , Gregory A Norris , Rebecca J Chapman , Rui Fu , Nicholas Willard , Andrea M Griesinger , Graziella Ribeiro de Sousa , Vladimir Amani , Enrique Grimaldo , Todd C Hankinson , Ffyona Booker , Martin Sill , Richard G Grundy , Kristian W Pajtler , David W Ellison , Nicholas K Foreman , Timothy A Ritzmann

Neuroblastoma Predisposition and Surveillance-An Update from the 2023 AACR Childhood Cancer Predisposition Workshop.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Junne Kamihara , Lisa R Diller , William D Foulkes , Orli Michaeli , Yoshiko Nakano , Kristian W Pajtler , Melissa Perrino , Sarah R Scollon , Douglas R Stewart , Stephan Voss , Rosanna Weksberg , Jordan R Hansford , Garrett M Brodeur

Update on surveillance guidelines in emerging Wilms tumor predisposition syndromes.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Jack J Brzezinski , Kerri D Becktell , Gaëlle Bougeard , Garrett M Brodeur , Lisa R Diller , Andrea S Doria , Jordan R Hansford , Wendy K Kohlmann , Christian P Kratz , Suzanne P MacFarland , Kristian W Pajtler , Surya P Rednam , Jaclyn Schienda , Lisa J States , Anita Villani , Rosanna Weksberg , Kristin Zelley , Gail E Tomlinson , Jennifer M Kalish

EZHIP/CXorf67 mimics K27M mutated oncohistones and functions as an intrinsic inhibitor of PRC2 function in aggressive posterior fossa ependymoma.

Neuro-oncology

Avec: Jens-Martin Hübner , Torsten Müller , Dimitris N Papageorgiou , Monika Mauermann , Jeroen Krijgsveld , Robert B Russell , David W Ellison , Stefan M Pfister , Kristian W Pajtler , Marcel Kool

MYCN amplification drives an aggressive form of spinal ependymoma.

Acta neuropathologica

Avec: David R Ghasemi , Martin Sill , Konstantin Okonechnikov , Andrey Korshunov , Stephen Yip , Peter W Schutz , David Scheie , Anders Kruse , Patrick N Harter , Marina Kastelan , Marlies Wagner , Christian Hartmann , Julia Benzel , Kendra K Maass , Mustafa Khasraw , Ronald Sträter , Christian Thomas , Werner Paulus , Christian P Kratz , Hendrik Witt , Daisuke Kawauchi , Christel Herold-Mende , Felix Sahm , Sebastian Brandner , Marcel Kool , David T W Jones , Andreas von Deimling , Stefan M Pfister , David E Reuss , Kristian W Pajtler

Systemic chemotherapy of pediatric recurrent ependymomas: results from the German HIT-REZ studies.

Journal of neuro-oncology

Avec: Jonas E Adolph , Gudrun Fleischhack , Christine Gaab , Ruth Mikasch , Martin Mynarek , Stefan Rutkowski , Ulrich Schüller , Stefan M Pfister , Kristian W Pajtler , Till Milde , Olaf Witt , Brigitte Bison , Monika Warmuth-Metz , Rolf-Dieter Kortmann , Stefan Dietzsch , Torsten Pietsch , Beate Timmermann , Stephan Tippelt , Auteur inconnu

Local and systemic therapy of recurrent ependymoma in children and adolescents: short- and long-term results of the E-HIT-REZ 2005 study.

Neuro-oncology

Avec: Jonas E Adolph , Gudrun Fleischhack , Ruth Mikasch , Julia Zeller , Monika Warmuth-Metz , Brigitte Bison , Martin Mynarek , Stefan Rutkowski , Ulrich Schüller , Katja von Hoff , Denise Obrecht , Torsten Pietsch , Stefan M Pfister , Kristian W Pajtler , Olaf Witt , Hendrik Witt , Rolf-Dieter Kortmann , Beate Timmermann , Jürgen Krauß , Michael C Frühwald , Andreas Faldum , Robert Kwiecien , Udo Bode , Stephan Tippelt

Predisposition to cancer in children and adolescents.

The Lancet. Child & adolescent health

Avec: Christian P Kratz , Marjolijn C Jongmans , Hélène Cavé , Katharina Wimmer , Sam Behjati , Lea Guerrini-Rousseau , Till Milde , Kristian W Pajtler , Lisa Golmard , Marion Gauthier-Villars , Rosalyn Jewell , Catriona Duncan , Eamonn R Maher , Laurence Brugieres , Kathy Pritchard-Jones , Franck Bourdeaut

Current recommendations for clinical surveillance and genetic testing in rhabdoid tumor predisposition: a report from the SIOPE Host Genome Working Group.

Familial cancer

Avec: M C Frühwald , K Nemes , H Boztug , M C A Cornips , D G Evans , R Farah , S Glentis , M Jorgensen , K Katsibardi , S Hirsch , K Jahnukainen , I Kventsel , K Kerl , C P Kratz , K W Pajtler , U Kordes , V Ridola , E Stutz , F Bourdeaut

Response to trametinib treatment in progressive pediatric low-grade glioma patients.

Journal of neuro-oncology

Avec: Florian Selt , Cornelis M van Tilburg , Brigitte Bison , Philipp Sievers , Inga Harting , Jonas Ecker , Kristian W Pajtler , Felix Sahm , Annabelle Bahr , Michèle Simon , David T W Jones , Lennart Well , Victor-Felix Mautner , David Capper , Pablo Hernáiz Driever , Astrid Gnekow , Stefan M Pfister , Olaf Witt , Till Milde

The Pediatric Precision Oncology INFORM Registry: Clinical Outcome and Benefit for Patients with Very High-Evidence Targets.

Cancer discovery

Avec: Cornelis M van Tilburg , Elke Pfaff , Kristian W Pajtler , Karin P S Langenberg , Petra Fiesel , Barbara C Jones , Gnana Prakash Balasubramanian , Sebastian Stark , Pascal D Johann , Mirjam Blattner-Johnson , Kathrin Schramm , Nicola Dikow , Steffen Hirsch , Christian Sutter , Kerstin Grund , Arend von Stackelberg , Andreas E Kulozik , Andrej Lissat , Arndt Borkhardt , Roland Meisel , Dirk Reinhardt , Jan-Henning Klusmann , Gudrun Fleischhack , Stephan Tippelt , Dietrich von Schweinitz , Irene Schmid , Christof M Kramm , André O von Bueren , Gabriele Calaminus , Peter Vorwerk , Norbert Graf , Frank Westermann , Matthias Fischer , Angelika Eggert , Birgit Burkhardt , Wilhelm Wößmann , Michaela Nathrath , Stefanie Hecker-Nolting , Michael C Frühwald , Dominik T Schneider , Ines B Brecht , Petra Ketteler , Simone Fulda , Ewa Koscielniak , Michael T Meister , Monika Scheer , Simone Hettmer , Matthias Schwab , Roman Tremmel , Ingrid Øra , Caroline Hutter , Nicolas U Gerber , Olli Lohi , Bernarda Kazanowska , Antonis Kattamis , Maria Filippidou , Bianca Goemans , C Michel Zwaan , Till Milde , Natalie Jäger , Stephan Wolf , David Reuss , Felix Sahm , Andreas von Deimling , Uta Dirksen , Angelika Freitag , Ruth Witt , Peter Lichter , Annette Kopp-Schneider , David T W Jones , Jan J Molenaar , David Capper , Stefan M Pfister , Olaf Witt

Development of Randomized Trials in Adults with Medulloblastoma-The Example of EORTC 1634-BTG/NOA-23.

Cancers

Avec: Peter Hau , Didier Frappaz , Elizabeth Hovey , Martin G McCabe , Kristian W Pajtler , Benedikt Wiestler , Clemens Seidel , Stephanie E Combs , Linda Dirven , Martin Klein , Antoinette Anazodo , Elke Hattingen , Silvia Hofer , Stefan M Pfister , Claus Zimmer , Rolf-Dieter Kortmann , Marie-Pierre Sunyach , Ronan Tanguy , Rachel Effeney , Andreas von Deimling , Felix Sahm , Stefan Rutkowski , Anna S Berghoff , Enrico Franceschi , Estela Pineda , Dagmar Beier , Ellen Peeters , Thierry Gorlia , Maureen Vanlancker , Jacoline E C Bromberg , Julien Gautier , David S Ziegler , Matthias Preusser , Wolfgang Wick , Michael Weller

The significance of margins in pediatric Non-Rhabdomyosarcoma soft tissue sarcomas: Consensus on surgical margin definition harmonization from the INternational Soft Tissue SaRcoma ConsorTium (INSTRuCT).

Cancer medicine

Avec: Monika Sparber-Sauer , Andrea Ferrari , Sheri L Spunt , Christian Vokuhl , Dana Casey , Timothy B Lautz , William H Meyer , David O Walterhouse , Kristian W Pajtler , Rita Alaggio , Andreas Schmidt , Akmal Safwat , Beate Timmermann , Patrizia Dall'Igna , Sonja Chen , Aaron R Weiss , Daniel Orbach

Second-line treatment of pediatric patients with relapsed rhabdomyosarcoma adapted to initial risk stratification: Data of the European Soft Tissue Sarcoma Registry (SoTiSaR).

Pediatric blood & cancer

Avec: Amadeus T Heinz , Martin Ebinger , Anton Schönstein , Jörg Fuchs , Beate Timmermann , Guido Seitz , Christian Vokuhl , Marc W Münter , Kristian W Pajtler , Sabine Stegmaier , Thekla von Kalle , Christian P Kratz , Jochen Rößler , Gustaf Ljungman , Thomas Klingebiel , Ewa Koscielniak , Monika Sparber-Sauer , Auteur inconnu

3D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma.

Nature communications

Avec: Konstantin Okonechnikov , Aylin Camgöz , Owen Chapman , Sameena Wani , Donglim Esther Park , Jens-Martin Hübner , Abhijit Chakraborty , Meghana Pagadala , Rosalind Bump , Sahaana Chandran , Katerina Kraft , Rocio Acuna-Hidalgo , Derek Reid , Kristin Sikkink , Monika Mauermann , Edwin F Juarez , Anne Jenseit , James T Robinson , Kristian W Pajtler , Till Milde , Natalie Jäger , Petra Fiesel , Ling Morgan , Sunita Sridhar , Nicole G Coufal , Michael Levy , Denise Malicki , Charlotte Hobbs , Stephen Kingsmore , Shareef Nahas , Matija Snuderl , John Crawford , Robert J Wechsler-Reya , Tom Belle Davidson , Jennifer Cotter , George Michaiel , Gudrun Fleischhack , Stefan Mundlos , Anthony Schmitt , Hannah Carter , Kulandaimanuvel Antony Michealraj , Sachin A Kumar , Michael D Taylor , Jeremy Rich , Frank Buchholz , Jill P Mesirov , Stefan M Pfister , Ferhat Ay , Jesse R Dixon , Marcel Kool , Lukas Chavez

Developmental basis of SHH medulloblastoma heterogeneity.

Nature communications

Avec: Maxwell P Gold , Winnie Ong , Andrew M Masteller , David R Ghasemi , Julie Anne Galindo , Noel R Park , Nhan C Huynh , Aneesh Donde , Veronika Pister , Raul A Saurez , Maria C Vladoiu , Grace H Hwang , Tanja Eisemann , Laura K Donovan , Adam D Walker , Joseph Benetatos , Christelle Dufour , Livia Garzia , Rosalind A Segal , Robert J Wechsler-Reya , Jill P Mesirov , Andrey Korshunov , Kristian W Pajtler , Scott L Pomeroy , Olivier Ayrault , Shawn M Davidson , Jennifer A Cotter , Michael D Taylor , Ernest Fraenkel

Update on cancer predisposition syndromes and surveillance guidelines for childhood brain tumors.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Jordan R Hansford , Anirban Das , Rose B McGee , Yoshiko Nakano , Jack Brzezinski , Sarah R Scollon , Surya P Rednam , Jaclyn Schienda , Orli Michaeli , Sun Young Kim , Mary-Louise C Greer , Rosanna Weksberg , Douglas R Stewart , William D Foulkes , Uri Tabori , Kristian W Pajtler , Stefan M Pfister , Garrett M Brodeur , Junne Kamihara

Adult Medulloblastoma: Updates on Current Management and Future Perspectives.

Cancers

Avec: Enrico Franceschi , Caterina Giannini , Julia Furtner , Kristian W Pajtler , Sofia Asioli , Raphael Guzman , Clemens Seidel , Lidia Gatto , Peter Hau

Significance of fusion status, Oberlin risk factors, local and maintenance treatment in pediatric and adolescent patients with metastatic rhabdomyosarcoma: Data of the European Soft Tissue Sarcoma Registry SoTiSaR.

Pediatric blood & cancer

Avec: Amadeus T Heinz , Anton Schönstein , Martin Ebinger , Jörg Fuchs , Beate Timmermann , Guido Seitz , Christian Vokuhl , Marc Münter , Kristian W Pajtler , Sabine Stegmaier , Thekla von Kalle , Christian P Kratz , Gustaf Ljungman , Hanna Juntti , Thomas Klingebiel , Ewa Koscielniak , Monika Sparber-Sauer , Auteur inconnu

Genomic characterization of IDH-mutant astrocytoma progression to grade 4 in the treatment setting.

Acta neuropathologica communications

Avec: Kirsi J Rautajoki , Serafiina Jaatinen , Anja Hartewig , Aliisa M Tiihonen , Matti Annala , Iida Salonen , Masi Valkonen , Vili Simola , Elisa M Vuorinen , Anni Kivinen , Minna J Rauhala , Riikka Nurminen , Kendra K Maass , Sirpa-Liisa Lahtela , Arja Jukkola , Olli Yli-Harja , Pauli Helén , Kristian W Pajtler , Pekka Ruusuvuori , Joonas Haapasalo , Wei Zhang , Hannu Haapasalo , Matti Nykter

Réseau de co-auteurs

Stefan M Pfister 43 collaborations

David T W Jones 22 collaborations

Till Milde 22 collaborations

Felix Sahm 20 collaborations

Marcel Kool 20 collaborations

Andrey Korshunov 17 collaborations

Olaf Witt 16 collaborations

Andreas von Deimling 15 collaborations

Stefan Rutkowski 13 collaborations

Martin Sill 13 collaborations

Ulrich Schüller 11 collaborations

Torsten Pietsch 11 collaborations

Konstantin Okonechnikov 10 collaborations

Julia Benzel 10 collaborations

David R Ghasemi 9 collaborations

Christine Haberler 9 collaborations

Cornelis M van Tilburg 9 collaborations

Jonas Ecker 9 collaborations

Florian Selt 9 collaborations

Dominik Sturm 9 collaborations

Kendra K Maass 9 collaborations

Christian P Kratz 9 collaborations

Philipp Sievers 8 collaborations

David Capper 8 collaborations

David W Ellison 8 collaborations

Matija Snuderl 8 collaborations

Gudrun Fleischhack 8 collaborations

Natalie Jäger 8 collaborations

Martin Mynarek 7 collaborations

Hendrik Witt 7 collaborations

Jordan R Hansford 7 collaborations

Johannes Gojo 7 collaborations

Beate Timmermann 7 collaborations

Daisuke Kawauchi 7 collaborations

David E Reuss 6 collaborations

Walter E Haefeli 6 collaborations

Jürgen Burhenne 6 collaborations

Richard G Grundy 6 collaborations

Wolfgang Wick 6 collaborations

Brigitte Bison 6 collaborations

Rolf-Dieter Kortmann 6 collaborations

Damian Stichel 5 collaborations

Daniel Schrimpf 5 collaborations

Denise Obrecht 5 collaborations

Christian Thomas 5 collaborations

Pascale Varlet 5 collaborations

Eric Bouffet 5 collaborations

Andrew M Donson 5 collaborations

Steffen Hirsch 5 collaborations

Sebastian Brandner 5 collaborations

Christian Vokuhl 5 collaborations

Nicholas K Foreman 5 collaborations

Monika Sparber-Sauer 5 collaborations

Stephan Tippelt 5 collaborations

None None 5 collaborations

Katja von Hoff 5 collaborations

Irene Slavc 4 collaborations

Martin Hasselblatt 4 collaborations

Stephan Frank 4 collaborations

Elke Pfaff 4 collaborations

Mirjam Blattner-Johnson 4 collaborations

Ruth Witt 4 collaborations

Michael C Frühwald 4 collaborations

Pablo Hernáiz Driever 4 collaborations

Martin Ebinger 4 collaborations

Peter Lichter 4 collaborations

Christof M Kramm 4 collaborations

Werner Paulus 4 collaborations

David Scheie 4 collaborations

Kenneth Aldape 4 collaborations

Romain Sigaud 4 collaborations

Ina Oehme 4 collaborations

Felice Giangaspero 4 collaborations

Michael D Taylor 4 collaborations

Vijay Ramaswamy 4 collaborations

Thomas Klingebiel 4 collaborations

Richard J Gilbertson 4 collaborations

Monika Warmuth-Metz 4 collaborations

Ewa Koscielniak 4 collaborations

Enrico Franceschi 4 collaborations

Peter Hau 4 collaborations

Garrett M Brodeur 4 collaborations

Rosanna Weksberg 4 collaborations

Marina Ryzhova 3 collaborations

Angela Mastronuzzi 3 collaborations

Annika K Wefers 3 collaborations

Gnana Prakash Balasubramanian 3 collaborations

Sebastian Stark 3 collaborations

Petra Fiesel 3 collaborations

Christel Herold-Mende 3 collaborations

Angelika Eggert 3 collaborations

Arnault Tauziède-Espariat 3 collaborations

Felipe Andreiuolo 3 collaborations

Leonille Schweizer 3 collaborations

Uwe Kordes 3 collaborations

William D Foulkes 3 collaborations

Max Sauter 3 collaborations

Timothy A Ritzmann 3 collaborations

Rebecca J Chapman 3 collaborations

Piergiorgio Modena 3 collaborations

Thomas S Jacques 3 collaborations

Margaux Fresnais 3 collaborations

Rémi Longuespée 3 collaborations

Zied Abdullaev 3 collaborations

Dennis Friedel 3 collaborations

Nicola Dikow 3 collaborations

Christian Sutter 3 collaborations

Maura Massimino 3 collaborations

Thomas E Merchant 3 collaborations

Christine L White 3 collaborations

Nicholas G Gottardo 3 collaborations

Volker Hovestadt 3 collaborations

Michael Platten 3 collaborations

Pieter Wesseling 3 collaborations

Uta Dirksen 3 collaborations

Bernhard Englinger 3 collaborations

Sibylle Madlener 3 collaborations

Dominik Kirchhofer 3 collaborations

Christian Dorfer 3 collaborations

Lisa Mayr 3 collaborations

Andreas Peyrl 3 collaborations

Thomas Czech 3 collaborations

Walter Berger 3 collaborations

Mariella G Filbin 3 collaborations

Brent A Orr 3 collaborations

Paul A Northcott 3 collaborations

Jens-Martin Hübner 3 collaborations

Heike Peterziel 3 collaborations

Marc Zuckermann 3 collaborations

Jonas E Adolph 3 collaborations

Ruth Mikasch 3 collaborations

Felix Hinz 3 collaborations

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