Samuel A Sprowls

Affiliations

Department of Pharmaceutical Sciences, School of Pharmacy, West Virginia University HSC, Morgantown, West Virginia 26506, USA.

Publications (18)

Improving CNS Delivery to Brain Metastases by Blood-Tumor Barrier Disruption.

Trends in cancer

Avec: Samuel A Sprowls , Tasneem A Arsiwala , Jacob R Bumgarner , Neal Shah , Sundus S Lateef , Brooke N Kielkowski , Paul R Lockman

Circadian Influences on Chemotherapy Efficacy in a Mouse Model of Brain Metastases of Breast Cancer.

Frontiers in oncology

Avec: William H Walker , Samuel A Sprowls , Jacob R Bumgarner , Jennifer A Liu , O Hecmarie Meléndez-Fernández , James C Walton , Paul R Lockman , A Courtney DeVries , Randy J Nelson

Blood-tumor barrier opening by MRI-guided transcranial focused ultrasound in a preclinical breast cancer brain metastasis model improves efficacy of combinatorial chemotherapy.

Frontiers in oncology

Avec: Tasneem A Arsiwala , Kathryn E Blethen , Cullen P Wolford , Dhruvi M Panchal , Samuel A Sprowls , Ross A Fladeland , Brooke N Kielkowski , Trenton A Pritt , Peng Wang , Olivia Wilson , Jeffrey S Carpenter , Victor Finomore , Ali Rezai , Paul R Lockman

Drug resistance occurred in a newly characterized preclinical model of lung cancer brain metastasis.

BMC cancer

Avec: Neal Shah , Zhongwei Liu , Rachel M Tallman , Afroz Mohammad , Samuel A Sprowls , Pushkar A Saralkar , Schuyler D Vickers , Mark V Pinti , Weimin Gao , Paul R Lockman

Overcoming the acquired resistance to gefitinib in lung cancer brain metastasis in vitro and in vivo.

Archives of toxicology

Avec: Zhongwei Liu , Neal Shah , Kent L Marshall , Samuel A Sprowls , Pushkar Saralkar , Afroz Mohammad , Kathryn E Blethen , Tasneem A Arsiwala , Ross Fladeland , Paul R Lockman , Weimin Gao

Characterization of passive permeability after low intensity focused ultrasound mediated blood-brain barrier disruption in a preclinical model.

Fluids and barriers of the CNS

Avec: Tasneem A Arsiwala , Samuel A Sprowls , Kathryn E Blethen , Ross A Fladeland , Cullen P Wolford , Brooke N Kielkowski , Morgan J Glass , Peng Wang , Olivia Wilson , Jeffrey S Carpenter , Manish Ranjan , Victor Finomore , Ali Rezai , Paul R Lockman

Chemotherapeutic Activity of Pitavastatin in Vincristine Resistant B-Cell Acute Lymphoblastic Leukemia.

Cancers

Avec: Debbie Piktel , Javohn C Moore , Sloan Nesbit , Samuel A Sprowls , Michael D Craig , Stephanie L Rellick , Rajesh R Nair , Ethan Meadows , John M Hollander , Werner J Geldenhuys , Karen H Martin , Laura F Gibson

Development of a Cx46 Targeting Strategy for Cancer Stem Cells.

Cell reports

Avec: Erin E Mulkearns-Hubert , Luke A Torre-Healy , Daniel J Silver , Jennifer T Eurich , Defne Bayik , Emily Serbinowski , Masahiro Hitomi , John Zhou , Bartlomiej Przychodzen , Renliang Zhang , Samuel A Sprowls , James S Hale , Tyler J Alban , Artem Berezovsky , Brent A Bell , Paul R Lockman , Babal K Jha , Justin D Lathia

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition.

Journal of visualized experiments : JoVE

Avec: Samuel A Sprowls , Vincenzo J Pizzuti , William Pentz , Divine C Nwafor , R Alfredo C Siochi , Paul R Lockman

Breaking down the barrier to medulloblastoma treatment: Piezo2 knockout disrupts the BTB and increases vascular permeability.

Neuron

Avec: Samuel A Sprowls , Justin D Lathia

MiR-34a Interacts with Cytochrome c and Shapes Stroke Outcomes.

Scientific reports

Avec: Heng Hu , Emily A Hone , Edward A P Provencher , Samuel A Sprowls , Imran Farooqi , Deborah R Corbin , Saumyendra N Sarkar , John M Hollander , Paul R Lockman , James W Simpkins , Xuefang Ren

Ultrasound-mediated disruption of the blood tumor barrier for improved therapeutic delivery.

Neoplasia (New York, N.Y.)

Avec: T A Arsiwala , S A Sprowls , K E Blethen , C E Adkins , P A Saralkar , R A Fladeland , W Pentz , A Gabriele , B Kielkowski , R I Mehta , P Wang , J S Carpenter , M Ranjan , U Najib , A R Rezai , P R Lockman

Y Chromosome LncRNA Are Involved in Radiation Response of Male Non-Small Cell Lung Cancer Cells.

Cancer research

Avec: Tayvia Brownmiller , Jamie A Juric , Abby D Ivey , Brandon M Harvey , Emily S Westemeier , Michael T Winters , Alyson M Stevens , Alana N Stanley , Karen E Hayes , Samuel A Sprowls , Amanda S Gatesman Ammer , Mackenzee Walker , Erik A Bey , Xiaoliang Wu , Zuan-Fu Lim , Lin Zhu , Sijin Wen , Gangqing Hu , Patrick C Ma , Ivan Martinez

Modulation of the blood-tumor barrier to enhance drug delivery and efficacy for brain metastases.

Neuro-oncology advances

Avec: Kathryn E Blethen , Tasneem A Arsiwala , Ross A Fladeland , Samuel A Sprowls , Dhruvi M Panchal , Chris E Adkins , Brooke N Kielkowski , Leland E Earp , Morgan J Glass , Trenton A Pritt , Yssabela M Cabuyao , Sonikpreet Aulakh , Paul R Lockman

A Review of Mathematics Determining Solute Uptake at the Blood-Brain Barrier in Normal and Pathological Conditions.

Pharmaceutics

Avec: Samuel A Sprowls , Pushkar Saralkar , Tasneem Arsiwala , Christopher E Adkins , Kathryn E Blethen , Vincenzo J Pizzuti , Neal Shah , Ross Fladeland , Paul R Lockman

WDR5 represents a therapeutically exploitable target for cancer stem cells in glioblastoma.

Genes & development

Avec: Kelly Mitchell , Samuel A Sprowls , Sonali Arora , Sajina Shakya , Daniel J Silver , Christopher M Goins , Lisa Wallace , Gustavo Roversi , Rachel E Schafer , Kristen Kay , Tyler E Miller , Adam Lauko , John Bassett , Anjali Kashyap , Jonathan D'Amato Kass , Erin E Mulkearns-Hubert , Sadie Johnson , Joseph Alvarado , Jeremy N Rich , Eric C Holland , Patrick J Paddison , Anoop P Patel , Shaun R Stauffer , Christopher G Hubert , Justin D Lathia

Effects of whole-brain radiation therapy on the blood-brain barrier in immunocompetent and immunocompromised mouse models.

Radiation oncology (London, England)

Avec: K E Blethen , S A Sprowls , T A Arsiwala , C P Wolford , D M Panchal , R A Fladeland , M J Glass , L P Dykstra , B N Kielkowski , J R Blackburn , C J Andrick , P R Lockman

GAP43-dependent mitochondria transfer from astrocytes enhances glioblastoma tumorigenicity.

Nature cancer

Avec: Dionysios C Watson , Defne Bayik , Simon Storevik , Shannon Sherwin Moreino , Samuel A Sprowls , Jianhua Han , Mina Thue Augustsson , Adam Lauko , Palavalasa Sravya , Gro Vatne Røsland , Katie Troike , Karl Johan Tronstad , Sabrina Wang , Katharina Sarnow , Kristen Kay , Taral R Lunavat , Daniel J Silver , Sahil Dayal , Justin Vareecal Joseph , Erin Mulkearns-Hubert , Lars Andreas Rømo Ystaas , Gauravi Deshpande , Joris Guyon , Yadi Zhou , Capucine R Magaut , Juliana Seder , Laura Neises , Sarah E Williford , Johannes Meiser , Andrew J Scott , Peter Sajjakulnukit , Jason A Mears , Rolf Bjerkvig , Abhishek Chakraborty , Thomas Daubon , Feixiong Cheng , Costas A Lyssiotis , Daniel R Wahl , Anita B Hjelmeland , Jubayer A Hossain , Hrvoje Miletic , Justin D Lathia

Réseau de co-auteurs

Paul R Lockman 11 collaborations

Tasneem A Arsiwala 5 collaborations

Kathryn E Blethen 5 collaborations

Neal Shah 4 collaborations

Brooke N Kielkowski 4 collaborations

Justin D Lathia 4 collaborations

Ross A Fladeland 3 collaborations

Daniel J Silver 3 collaborations

Jacob R Bumgarner 2 collaborations

Cullen P Wolford 2 collaborations

Dhruvi M Panchal 2 collaborations

Trenton A Pritt 2 collaborations

Peng Wang 2 collaborations

Olivia Wilson 2 collaborations

Jeffrey S Carpenter 2 collaborations

Victor Finomore 2 collaborations

Ali Rezai 2 collaborations

Zhongwei Liu 2 collaborations

Afroz Mohammad 2 collaborations

Weimin Gao 2 collaborations

Pushkar Saralkar 2 collaborations

Ross Fladeland 2 collaborations

Morgan J Glass 2 collaborations

John M Hollander 2 collaborations

Erin E Mulkearns-Hubert 2 collaborations

Defne Bayik 2 collaborations

Vincenzo J Pizzuti 2 collaborations

T A Arsiwala 2 collaborations

S A Sprowls 2 collaborations

K E Blethen 2 collaborations

R A Fladeland 2 collaborations

P R Lockman 2 collaborations

Kristen Kay 2 collaborations

Adam Lauko 2 collaborations

Sundus S Lateef 1 collaboration

William H Walker 1 collaboration

Jennifer A Liu 1 collaboration

O Hecmarie Meléndez-Fernández 1 collaboration

James C Walton 1 collaboration

A Courtney DeVries 1 collaboration

Randy J Nelson 1 collaboration

Rachel M Tallman 1 collaboration

Pushkar A Saralkar 1 collaboration

Schuyler D Vickers 1 collaboration

Mark V Pinti 1 collaboration

Kent L Marshall 1 collaboration

Manish Ranjan 1 collaboration

Debbie Piktel 1 collaboration

Javohn C Moore 1 collaboration

Sloan Nesbit 1 collaboration

Michael D Craig 1 collaboration

Stephanie L Rellick 1 collaboration

Rajesh R Nair 1 collaboration

Ethan Meadows 1 collaboration

Werner J Geldenhuys 1 collaboration

Karen H Martin 1 collaboration

Laura F Gibson 1 collaboration

Luke A Torre-Healy 1 collaboration

Jennifer T Eurich 1 collaboration

Emily Serbinowski 1 collaboration

Masahiro Hitomi 1 collaboration

John Zhou 1 collaboration

Bartlomiej Przychodzen 1 collaboration

Renliang Zhang 1 collaboration

James S Hale 1 collaboration

Tyler J Alban 1 collaboration

Artem Berezovsky 1 collaboration

Brent A Bell 1 collaboration

Babal K Jha 1 collaboration

William Pentz 1 collaboration

Divine C Nwafor 1 collaboration

R Alfredo C Siochi 1 collaboration

Heng Hu 1 collaboration

Emily A Hone 1 collaboration

Edward A P Provencher 1 collaboration

Imran Farooqi 1 collaboration

Deborah R Corbin 1 collaboration

Saumyendra N Sarkar 1 collaboration

James W Simpkins 1 collaboration

Xuefang Ren 1 collaboration

C E Adkins 1 collaboration

P A Saralkar 1 collaboration

W Pentz 1 collaboration

A Gabriele 1 collaboration

B Kielkowski 1 collaboration

R I Mehta 1 collaboration

P Wang 1 collaboration

J S Carpenter 1 collaboration

M Ranjan 1 collaboration

U Najib 1 collaboration

A R Rezai 1 collaboration

Tayvia Brownmiller 1 collaboration

Jamie A Juric 1 collaboration

Abby D Ivey 1 collaboration

Brandon M Harvey 1 collaboration

Emily S Westemeier 1 collaboration

Michael T Winters 1 collaboration

Alyson M Stevens 1 collaboration

Alana N Stanley 1 collaboration

Karen E Hayes 1 collaboration

Amanda S Gatesman Ammer 1 collaboration

Mackenzee Walker 1 collaboration

Erik A Bey 1 collaboration

Xiaoliang Wu 1 collaboration

Zuan-Fu Lim 1 collaboration

Lin Zhu 1 collaboration

Sijin Wen 1 collaboration

Gangqing Hu 1 collaboration

Patrick C Ma 1 collaboration

Ivan Martinez 1 collaboration

Chris E Adkins 1 collaboration

Leland E Earp 1 collaboration

Yssabela M Cabuyao 1 collaboration

Sonikpreet Aulakh 1 collaboration

Tasneem Arsiwala 1 collaboration

Christopher E Adkins 1 collaboration

Kelly Mitchell 1 collaboration

Sonali Arora 1 collaboration

Sajina Shakya 1 collaboration

Christopher M Goins 1 collaboration

Lisa Wallace 1 collaboration

Gustavo Roversi 1 collaboration

Rachel E Schafer 1 collaboration

Tyler E Miller 1 collaboration

John Bassett 1 collaboration

Anjali Kashyap 1 collaboration

Jonathan D'Amato Kass 1 collaboration

Sadie Johnson 1 collaboration

Joseph Alvarado 1 collaboration

Jeremy N Rich 1 collaboration

Eric C Holland 1 collaboration

Patrick J Paddison 1 collaboration

Anoop P Patel 1 collaboration

Shaun R Stauffer 1 collaboration

Christopher G Hubert 1 collaboration

C P Wolford 1 collaboration

D M Panchal 1 collaboration

M J Glass 1 collaboration

L P Dykstra 1 collaboration

B N Kielkowski 1 collaboration

J R Blackburn 1 collaboration

C J Andrick 1 collaboration

Dionysios C Watson 1 collaboration

Simon Storevik 1 collaboration

Shannon Sherwin Moreino 1 collaboration

Jianhua Han 1 collaboration

Mina Thue Augustsson 1 collaboration

Palavalasa Sravya 1 collaboration

Gro Vatne Røsland 1 collaboration

Katie Troike 1 collaboration

Karl Johan Tronstad 1 collaboration

Sabrina Wang 1 collaboration

Katharina Sarnow 1 collaboration

Taral R Lunavat 1 collaboration

Sahil Dayal 1 collaboration

Justin Vareecal Joseph 1 collaboration

Erin Mulkearns-Hubert 1 collaboration

Lars Andreas Rømo Ystaas 1 collaboration

Gauravi Deshpande 1 collaboration

Joris Guyon 1 collaboration

Yadi Zhou 1 collaboration

Capucine R Magaut 1 collaboration

Juliana Seder 1 collaboration

Laura Neises 1 collaboration

Sarah E Williford 1 collaboration

Johannes Meiser 1 collaboration

Andrew J Scott 1 collaboration

Peter Sajjakulnukit 1 collaboration

Jason A Mears 1 collaboration

Rolf Bjerkvig 1 collaboration

Abhishek Chakraborty 1 collaboration

Thomas Daubon 1 collaboration

Feixiong Cheng 1 collaboration

Costas A Lyssiotis 1 collaboration

Daniel R Wahl 1 collaboration

Anita B Hjelmeland 1 collaboration

Jubayer A Hossain 1 collaboration

Hrvoje Miletic 1 collaboration