Titre : Système endocrine

Système endocrine : Questions médicales fréquentes

Termes MeSH sélectionnés :

Apnea

Questions fréquentes et termes MeSH associés

Diagnostic 5

#1

Comment diagnostiquer un déséquilibre hormonal ?

Des tests sanguins mesurant les niveaux hormonaux sont effectués.
Déséquilibre hormonal Tests hormonaux
#2

Quels examens pour les maladies endocriniennes ?

L'échographie, l'IRM et les tests de stimulation hormonale sont utilisés.
Maladies endocriniennes IRM
#3

Quels symptômes nécessitent un bilan hormonal ?

Fatigue, prise de poids inexpliquée, ou changements d'humeur peuvent indiquer un bilan.
Symptômes Bilan hormonal
#4

Comment évaluer la fonction thyroïdienne ?

Des tests de TSH, T3 et T4 sont réalisés pour évaluer la fonction thyroïdienne.
Fonction thyroïdienne TSH
#5

Quelles analyses pour le diabète ?

La glycémie à jeun et l'HbA1c sont des analyses clés pour diagnostiquer le diabète.
Diabète Glycémie

Symptômes 5

#1

Quels sont les symptômes d'une hyperthyroïdie ?

Perte de poids, nervosité, palpitations et transpiration excessive sont fréquents.
Hyperthyroïdie Symptômes
#2

Comment reconnaître un syndrome de Cushing ?

Obésité centrale, vergetures et hypertension artérielle sont des signes typiques.
Syndrome de Cushing Hypertension
#3

Quels signes d'un déséquilibre hormonal chez les femmes ?

Règles irrégulières, acné et changements d'humeur peuvent indiquer un déséquilibre.
Déséquilibre hormonal Règles irrégulières
#4

Quels symptômes d'un hypoparathyroïdisme ?

Tétanie, engourdissements et crampes musculaires sont des symptômes courants.
Hypoparathyroïdisme Tétanie
#5

Quels signes d'un diabète de type 1 ?

Soif excessive, urination fréquente et fatigue sont des symptômes à surveiller.
Diabète de type 1 Symptômes

Prévention 5

#1

Comment prévenir le diabète de type 2 ?

Maintenir un poids santé, faire de l'exercice et avoir une alimentation équilibrée aide.
Diabète de type 2 Prévention
#2

Quelles mesures pour éviter l'hypothyroïdie ?

Une alimentation riche en iode et un suivi médical régulier peuvent aider.
Hypothyroïdie Iode
#3

Comment réduire le risque de maladies endocriniennes ?

Un mode de vie sain, incluant une bonne nutrition et de l'exercice, est essentiel.
Maladies endocriniennes Mode de vie sain
#4

Quelles habitudes pour prévenir le syndrome des ovaires polykystiques ?

Maintenir un poids santé et gérer le stress peuvent réduire les risques.
Syndrome des ovaires polykystiques Poids santé
#5

Comment éviter les complications du diabète ?

Contrôler la glycémie et faire des examens réguliers sont cruciaux.
Diabète Glycémie

Traitements 5

#1

Comment traiter l'hypothyroïdie ?

Le traitement principal est la thérapie de remplacement hormonal avec la lévothyroxine.
Hypothyroïdie Thérapie de remplacement
#2

Quelles options pour le diabète de type 2 ?

Les médicaments oraux, l'insuline et les changements de mode de vie sont recommandés.
Diabète de type 2 Médicaments oraux
#3

Comment gérer le syndrome des ovaires polykystiques ?

Des contraceptifs oraux et des médicaments pour la résistance à l'insuline sont utilisés.
Syndrome des ovaires polykystiques Contraceptifs oraux
#4

Quel traitement pour l'hyperparathyroïdie ?

La chirurgie est souvent nécessaire pour retirer la glande parathyroïdienne affectée.
Hyperparathyroïdie Chirurgie
#5

Comment traiter le syndrome de Cushing ?

Le traitement peut inclure la chirurgie, la radiothérapie ou des médicaments spécifiques.
Syndrome de Cushing Radiothérapie

Complications 5

#1

Quelles complications de l'hyperthyroïdie ?

Les complications incluent des problèmes cardiaques et l'ostéoporose.
Hyperthyroïdie Complications
#2

Quels risques liés au diabète mal contrôlé ?

Les complications peuvent inclure des maladies cardiovasculaires et des neuropathies.
Diabète Maladies cardiovasculaires
#3

Quelles complications du syndrome de Cushing ?

Hypertension, diabète et infections fréquentes sont des complications possibles.
Syndrome de Cushing Hypertension
#4

Quels effets d'un hypoparathyroïdisme non traité ?

Des complications graves comme des convulsions et des problèmes cardiaques peuvent survenir.
Hypoparathyroïdisme Convulsions
#5

Quelles complications des maladies endocriniennes ?

Les maladies endocriniennes peuvent entraîner des troubles métaboliques et cardiovasculaires.
Maladies endocriniennes Troubles métaboliques

Facteurs de risque 5

#1

Quels facteurs de risque pour le diabète de type 2 ?

Obésité, sédentarité et antécédents familiaux augmentent le risque.
Diabète de type 2 Obésité
#2

Quels facteurs influencent l'hyperthyroïdie ?

L'âge, le sexe féminin et des antécédents familiaux sont des facteurs de risque.
Hyperthyroïdie Antécédents familiaux
#3

Quels risques liés au syndrome des ovaires polykystiques ?

L'obésité et la résistance à l'insuline sont des facteurs de risque majeurs.
Syndrome des ovaires polykystiques Résistance à l'insuline
#4

Quels facteurs de risque pour l'hypoparathyroïdisme ?

Les antécédents de chirurgie thyroïdienne et des maladies auto-immunes augmentent le risque.
Hypoparathyroïdisme Chirurgie thyroïdienne
#5

Quels facteurs de risque pour le syndrome de Cushing ?

L'utilisation prolongée de corticostéroïdes et certaines tumeurs peuvent être des facteurs.
Syndrome de Cushing Corticostéroïdes
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prevention and treatment of apnea in preterm infants.", "datePublished": "2023-10-04", "url": "https://questionsmedicales.fr/article/37791592", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1002/14651858.CD015462.pub2" } }, { "@type": "ScholarlyArticle", "name": "Frequent Apnea Attacks in a 1-Month-old Infant With Influenza C Virus Infection.", "datePublished": "2023-09-04", "url": "https://questionsmedicales.fr/article/37967034", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1097/INF.0000000000004088" } } ], "breadcrumb": { "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "questionsmedicales.fr", "item": "https://questionsmedicales.fr" }, { "@type": "ListItem", "position": 2, "name": "Système endocrine", "item": "https://questionsmedicales.fr/mesh/D004703" } ] } }, { "@type": "MedicalWebPage", "name": "Article complet : Système endocrine - Questions et réponses", "headline": "Questions et réponses médicales fréquentes sur Système endocrine", "description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.", "datePublished": "2026-08-25", "inLanguage": "fr", "hasPart": [ { "@type": "MedicalWebPage", "name": "Diagnostic", "headline": "Diagnostic sur Système endocrine", "description": "Comment diagnostiquer un déséquilibre hormonal ?\nQuels examens pour les maladies endocriniennes ?\nQuels symptômes nécessitent un bilan hormonal ?\nComment évaluer la fonction thyroïdienne ?\nQuelles analyses pour le diabète ?", "url": "https://questionsmedicales.fr/mesh/D004703?mesh_terms=Apnea#section-diagnostic" }, { "@type": "MedicalWebPage", "name": "Symptômes", "headline": "Symptômes sur Système endocrine", "description": "Quels sont les symptômes d'une hyperthyroïdie ?\nComment reconnaître un syndrome de Cushing ?\nQuels signes d'un déséquilibre hormonal chez les femmes ?\nQuels symptômes d'un hypoparathyroïdisme ?\nQuels signes d'un diabète de type 1 ?", "url": "https://questionsmedicales.fr/mesh/D004703?mesh_terms=Apnea#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Système endocrine", "description": "Comment prévenir le diabète de type 2 ?\nQuelles mesures pour éviter l'hypothyroïdie ?\nComment réduire le risque de maladies endocriniennes ?\nQuelles habitudes pour prévenir le syndrome des ovaires polykystiques ?\nComment éviter les complications du diabète ?", "url": "https://questionsmedicales.fr/mesh/D004703?mesh_terms=Apnea#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Système endocrine", "description": "Comment traiter l'hypothyroïdie ?\nQuelles options pour le diabète de type 2 ?\nComment gérer le syndrome des ovaires polykystiques ?\nQuel traitement pour l'hyperparathyroïdie ?\nComment traiter le syndrome de Cushing ?", "url": "https://questionsmedicales.fr/mesh/D004703?mesh_terms=Apnea#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Système endocrine", "description": "Quelles complications de l'hyperthyroïdie ?\nQuels risques liés au diabète mal contrôlé ?\nQuelles complications du syndrome de Cushing ?\nQuels effets d'un hypoparathyroïdisme non traité ?\nQuelles complications des maladies endocriniennes ?", "url": "https://questionsmedicales.fr/mesh/D004703?mesh_terms=Apnea#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Système endocrine", "description": "Quels facteurs de risque pour le diabète de type 2 ?\nQuels facteurs influencent l'hyperthyroïdie ?\nQuels risques liés au syndrome des ovaires polykystiques ?\nQuels facteurs de risque pour l'hypoparathyroïdisme ?\nQuels facteurs de risque pour le syndrome de Cushing ?", "url": "https://questionsmedicales.fr/mesh/D004703?mesh_terms=Apnea#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment diagnostiquer un déséquilibre hormonal ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "Des tests sanguins mesurant les niveaux hormonaux sont effectués." } }, { "@type": "Question", "name": "Quels examens pour les maladies endocriniennes ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "L'échographie, l'IRM et les tests de stimulation hormonale sont utilisés." } }, { "@type": "Question", "name": "Quels symptômes nécessitent un bilan hormonal ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Fatigue, prise de poids inexpliquée, ou changements d'humeur peuvent indiquer un bilan." } }, { "@type": "Question", "name": "Comment évaluer la fonction thyroïdienne ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Des tests de TSH, T3 et T4 sont réalisés pour évaluer la fonction thyroïdienne." } }, { "@type": "Question", "name": "Quelles analyses pour le diabète ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "La glycémie à jeun et l'HbA1c sont des analyses clés pour diagnostiquer le diabète." } }, { "@type": "Question", "name": "Quels sont les symptômes d'une hyperthyroïdie ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Perte de poids, nervosité, palpitations et transpiration excessive sont fréquents." } }, { "@type": "Question", "name": "Comment reconnaître un syndrome de Cushing ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Obésité centrale, vergetures et hypertension artérielle sont des signes typiques." } }, { "@type": "Question", "name": "Quels signes d'un déséquilibre hormonal chez les femmes ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Règles irrégulières, acné et changements d'humeur peuvent indiquer un déséquilibre." } }, { "@type": "Question", "name": "Quels symptômes d'un hypoparathyroïdisme ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Tétanie, engourdissements et crampes musculaires sont des symptômes courants." } }, { "@type": "Question", "name": "Quels signes d'un diabète de type 1 ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Soif excessive, urination fréquente et fatigue sont des symptômes à surveiller." } }, { "@type": "Question", "name": "Comment prévenir le diabète de type 2 ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "Maintenir un poids santé, faire de l'exercice et avoir une alimentation équilibrée aide." } }, { "@type": "Question", "name": "Quelles mesures pour éviter l'hypothyroïdie ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Une alimentation riche en iode et un suivi médical régulier peuvent aider." } }, { "@type": "Question", "name": "Comment réduire le risque de maladies endocriniennes ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Un mode de vie sain, incluant une bonne nutrition et de l'exercice, est essentiel." } }, { "@type": "Question", "name": "Quelles habitudes pour prévenir le syndrome des ovaires polykystiques ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Maintenir un poids santé et gérer le stress peuvent réduire les risques." } }, { "@type": "Question", "name": "Comment éviter les complications du diabète ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Contrôler la glycémie et faire des examens réguliers sont cruciaux." } }, { "@type": "Question", "name": "Comment traiter l'hypothyroïdie ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Le traitement principal est la thérapie de remplacement hormonal avec la lévothyroxine." } }, { "@type": "Question", "name": "Quelles options pour le diabète de type 2 ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "Les médicaments oraux, l'insuline et les changements de mode de vie sont recommandés." } }, { "@type": "Question", "name": "Comment gérer le syndrome des ovaires polykystiques ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "Des contraceptifs oraux et des médicaments pour la résistance à l'insuline sont utilisés." } }, { "@type": "Question", "name": "Quel traitement pour l'hyperparathyroïdie ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "La chirurgie est souvent nécessaire pour retirer la glande parathyroïdienne affectée." } }, { "@type": "Question", "name": "Comment traiter le syndrome de Cushing ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "Le traitement peut inclure la chirurgie, la radiothérapie ou des médicaments spécifiques." } }, { "@type": "Question", "name": "Quelles complications de l'hyperthyroïdie ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Les complications incluent des problèmes cardiaques et l'ostéoporose." } }, { "@type": "Question", "name": "Quels risques liés au diabète mal contrôlé ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Les complications peuvent inclure des maladies cardiovasculaires et des neuropathies." } }, { "@type": "Question", "name": "Quelles complications du syndrome de Cushing ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "Hypertension, diabète et infections fréquentes sont des complications possibles." } }, { "@type": "Question", "name": "Quels effets d'un hypoparathyroïdisme non traité ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Des complications graves comme des convulsions et des problèmes cardiaques peuvent survenir." } }, { "@type": "Question", "name": "Quelles complications des maladies endocriniennes ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "Les maladies endocriniennes peuvent entraîner des troubles métaboliques et cardiovasculaires." } }, { "@type": "Question", "name": "Quels facteurs de risque pour le diabète de type 2 ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "Obésité, sédentarité et antécédents familiaux augmentent le risque." } }, { "@type": "Question", "name": "Quels facteurs influencent l'hyperthyroïdie ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "L'âge, le sexe féminin et des antécédents familiaux sont des facteurs de risque." } }, { "@type": "Question", "name": "Quels risques liés au syndrome des ovaires polykystiques ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "L'obésité et la résistance à l'insuline sont des facteurs de risque majeurs." } }, { "@type": "Question", "name": "Quels facteurs de risque pour l'hypoparathyroïdisme ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Les antécédents de chirurgie thyroïdienne et des maladies auto-immunes augmentent le risque." } }, { "@type": "Question", "name": "Quels facteurs de risque pour le syndrome de Cushing ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "L'utilisation prolongée de corticostéroïdes et certaines tumeurs peuvent être des facteurs." } } ] } ] }
Dr Olivier Menir

Contenu validé par Dr Olivier Menir

Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale


Validation scientifique effectuée le 23/06/2026

Contenu vérifié selon les dernières recommandations médicales

Auteurs principaux

Roger Bouillon

3 publications dans cette catégorie

Affiliations :
  • Laboratory of Clinical and Experimental Endocrinology, Department of Chronic Diseases, Metabolism and Ageing KU Leuven Leuven Belgium.

Felix Beuschlein

2 publications dans cette catégorie

Affiliations :
  • Department of Endocrinology, Diabetology and Clinical Nutrition, University Hospital Zurich (USZ) and University of Zurich (UZH), 8091 Zurich, Switzerland.
  • Endocrine Research Unit, Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, 80336 Munich, Germany.
Publications dans "Système endocrine" :

Nicholas Emanuele

2 publications dans cette catégorie

Affiliations :
  • Endocrinology Section, Medical Service, VA Hospital, Hines, Illinois, USA.
Publications dans "Système endocrine" :

Caroline Poku

2 publications dans cette catégorie

Affiliations :
  • Department of Medicine, Division of Endocrinology, Loyola University Health Care System, Maywood, Illinois, USA.
Publications dans "Système endocrine" :

Mary Ann Emanuele

2 publications dans cette catégorie

Affiliations :
  • Department of Medicine, Division of Endocrinology, Loyola University Health Care System, Maywood, Illinois, USA. memanue@lumc.edu.
Publications dans "Système endocrine" :

Jose Manuel Quesada-Gomez

2 publications dans cette catégorie

Affiliations :
  • Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Hospital Universitario Reina Sofía, 14004 Córdoba, Spain.
  • Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, 28029 Madrid, Spain.

Ying Zhao

2 publications dans cette catégorie

Affiliations :
  • Geriatric Medicine Center, Key Laboratory of Endocrine Gland Diseases of Zhejiang Province, Department of Endocrinology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.
Publications dans "Système endocrine" :

Giuseppe Lisco

2 publications dans cette catégorie

Affiliations :
  • Interdisciplinary Department of Medicine, Section of Internal Medicine, Geriatrics, Endocrinology and Rare Diseases, School of Medicine, University of Bari "Aldo Moro", 70124 Bari, Italy.

Vito Angelo Giagulli

2 publications dans cette catégorie

Affiliations :
  • Interdisciplinary Department of Medicine, Section of Internal Medicine, Geriatrics, Endocrinology and Rare Diseases, School of Medicine, University of Bari "Aldo Moro", 70124 Bari, Italy.

Edoardo Guastamacchia

2 publications dans cette catégorie

Affiliations :
  • Interdisciplinary Department of Medicine, Section of Internal Medicine, Geriatrics, Endocrinology and Rare Diseases, School of Medicine, University of Bari "Aldo Moro", 70124 Bari, Italy.

Giovanni De Pergola

2 publications dans cette catégorie

Affiliations :
  • Department of Biomedical Sciences and Human Oncology, Section of Internal Medicine and Clinical Oncology, University of Bari Aldo Moro, 70124 Bari, Italy.
  • National Institute of Gastroenterology "Saverio de Bellis", Research Hospital, 70013 Castellana Grotte, Italy.

Vincenzo Triggiani

2 publications dans cette catégorie

Affiliations :
  • Interdisciplinary Department of Medicine, Section of Internal Medicine, Geriatrics, Endocrinology and Rare Diseases, School of Medicine, University of Bari "Aldo Moro", 70124 Bari, Italy.

Zhengwei Fu

2 publications dans cette catégorie

Affiliations :
  • Department of Biotechnology, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, 310014, China.
Publications dans "Système endocrine" :

Yuanxiang Jin

2 publications dans cette catégorie

Affiliations :
  • Department of Biotechnology, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, 310014, China. Electronic address: jinyx@zjut.edu.cn.
Publications dans "Système endocrine" :

Diego Muñoz Moreno

2 publications dans cette catégorie

Affiliations :
  • Servicio de Endocrinología y Nutrición, Hospital General Universitario Gregorio Marañón, Madrid, España. Electronic address: diego.munozm93@gmail.com.
Publications dans "Système endocrine" :

María Miguélez González

2 publications dans cette catégorie

Affiliations :
  • Servicio de Endocrinología y Nutrición, Hospital General Universitario Gregorio Marañón, Madrid, España.
Publications dans "Système endocrine" :

Laura González Fernández

2 publications dans cette catégorie

Affiliations :
  • Servicio de Endocrinología y Nutrición, Hospital General Universitario Gregorio Marañón, Madrid, España.
Publications dans "Système endocrine" :

Juan Carlos Percovich Hualpa

2 publications dans cette catégorie

Affiliations :
  • Servicio de Endocrinología y Nutrición, Hospital General Universitario Gregorio Marañón, Madrid, España.
Publications dans "Système endocrine" :

Michael P Reilly

2 publications dans cette catégorie

Affiliations :
  • Division of Pharmacology and Toxicology, College of Pharmacy, The University of Texas at Austin, Austin, Texas, USA.
Publications dans "Système endocrine" :

Andrea C Gore

2 publications dans cette catégorie

Affiliations :
  • Division of Pharmacology and Toxicology, College of Pharmacy, The University of Texas at Austin, Austin, Texas, USA.
  • Department of Psychology, The University of Texas at Austin, Austin, Texas, USA.
  • Institute for Neuroscience, The University of Texas at Austin, Austin, Texas, USA.
Publications dans "Système endocrine" :

Sources (1490 au total)

Methylxanthine for the prevention and treatment of apnea in preterm infants.

Very preterm infants often require respiratory support and are therefore exposed to an increased risk of chronic lung disease and later neurodevelopmental disability. Although methylxanthines are wide... To assess the effects of methylxanthines on the incidence of apnea, death, neurodevelopmental disability, and other longer-term outcomes in preterm infants (1) at risk for or with apnea, or (2) underg... We searched CENTRAL, MEDLINE, Embase, two other databases, and three trial registers (November 2022).... We included randomized trials in preterm infants, in which methylxanthines (aminophylline, caffeine, or theophylline) were compared to placebo or no treatment for any indication (i.e. prevention of ap... We used standard Cochrane methods and GRADE to assess the certainty of evidence.... We included 18 studies (2705 infants), evaluating the use of methylxanthine in preterm infants for: any indication (one study); prevention of apnea (six studies); treatment of apnea (five studies); an... Caffeine probably reduces the risk of death, major neurodevelopmental disability at 18 to 24 months, and the composite outcome DMND at 18 to 24 months. Administration of any methylxanthine to preterm ...

Doxapram for the prevention and treatment of apnea in preterm infants.

Apnea of prematurity is a common problem in preterm infants that may have significant consequences on their development. Methylxanthines (aminophylline, theophylline, and caffeine) are effective in th... To evaluate the benefits and harms of doxapram administration on the incidence of apnea and other short-term and longer-term clinical outcomes in preterm infants.... We used standard, extensive Cochrane search methods. The latest search date was March 2023.... We included randomized controlled trials (RCTs) assessing the role of doxapram in prevention and treatment of apnea of prematurity and prevention of reintubation in preterm infants (less than 37 weeks... We used standard Cochrane methods. Our primary outcomes were clinical apnea, need for positive pressure ventilation after initiation of treatment, failed apnea reduction after two to seven days, and f... We included eight RCTs enrolling 248 infants. Seven studies (214 participants) provided data for meta-analysis. Five studied doxapram for treatment of apnea in preterm infants. Three studied doxapram ... In treating apnea of prematurity, doxapram may slightly reduce failure in apnea reduction when compared to no treatment and there may be little to no difference in side effects against both no treatme...

Apnea or cyanosis as COVID-19 initial presentation in newborns.

The clinical manifestation of coronavirus disease 2019 (COVID-19) infection in newborns varies from asymptomatic infection to severe illness. Apnea or cyanosis as the earliest symptoms is rarely menti... This is a descriptive observational study with retrospectively collected data. All neonates under 30 days old and preterm infants with corrected gestational age of 44 weeks who had confirmed severe ac... During the two years of the study, 410 patients were admitted to the neonatal unit. Twenty-six patients (6.3%) presented with confirmed SARS-CoV-2 infection. The main clinical characteristic at admiss... Apnea and cyanosis can be a manifestation of SARS-CoV-2 infection in newborns, which suggests the need to include it in the diagnostic workup as other viral respiratory infections....

Caffeine versus other methylxanthines for the prevention and treatment of apnea in preterm infants.

Methylxanthines, including caffeine, theophylline, and aminophylline, work as stimulants of the respiratory drive, and decrease apnea of prematurity, a developmental disorder common in preterm infants... To assess the effects of caffeine compared to aminophylline or theophylline in preterm infants at risk of apnea, with apnea, or in the peri-extubation phase.... We searched CENTRAL, MEDLINE, Embase, Epistemonikos, the World Health Organization (WHO) International Clinical Trials Registry Platform (ICTRP), and clinicaltrials.gov in February 2023. We also check... Studies: randomized controlled trials (RCTs) and quasi-RCTs Participants: infants born before 34 weeks of gestation for prevention and extubation trials, and infants born before 37 weeks of gestation ... We used standard methodological procedures expected by Cochrane. We evaluated treatment effects using a fixed-effect model with risk ratio (RR), risk difference (RD), and 95% confidence intervals (CI)... We included 22 trials enrolling 1776 preterm infants. The indication for treatment was prevention of apnea in three studies, treatment of apnea in 13 studies, and extubation management in three studie... Although caffeine has been shown to improve important clinical outcomes, in the few studies that compared caffeine to other methylxanthines, there might be little to no difference in mortality, bronch...

Stress biomarker changes following a series of repeated static and dynamic apneas in non-divers.

This study examined the magnitude of physiological strain imposed by repeated maximal static and dynamic apneas through assessing a panel of stress-related biomarkers.... Eleven healthy men performed on three separate occasions (≥72-h apart): a series of five repeated maximal (i) static (STA) or (ii) dynamic apneas (DYN) or (iii) a static eupneic protocol (CTL). Venous... IMA was elevated after the apnoeic interventions (STA,+86%;DYN,+332%,p ≤ 0.047) but not CTL (p = 0.385). Myoglobin was higher than baseline (23.6 ± 3.9 ng/mL) 30-min post DYN (+70%,38.8 ± 13.3 ng/mL,p... Five repeated maximal DYN led to a greater muscle injury compared with STA but neither elicited myocardial injury or neuronal-parenchymal damage....

Establishment and validation of apnea risk prediction models in preterm infants: a retrospective case control study.

Apnea is common in preterm infants and can be accompanied with severe hypoxic damage. Early assessment of apnea risk can impact the prognosis of preterm infants. We constructed a prediction model to a... A total of 162 and 324 preterm infants with and without apnea who were admitted to the neonatal intensive care unit of Xiamen University between January 2018 and December 2021 were selected as the cas... Results of LASSO combined with multivariate logistic regression analysis showed that gestational age at birth, birth length, Apgar score, and neonatal respiratory distress syndrome were predictors of ... Our risk prediction model based on gestational age, birth length, Apgar score 10 min post-birth, and neonatal respiratory distress syndrome was validated in many aspects and had good predictive effica...

Altered amygdala volumes and microstructure in focal epilepsy patients with tonic-clonic seizures, ictal, and post-convulsive central apnea.

Sudden unexpected death in epilepsy (SUDEP) is a leading cause of death for patients with epilepsy; however, the pathophysiology remains unclear. Focal-to-bilateral tonic-clonic seizures (FBTCS) are a... Seventy-three patients with focal impaired awareness seizures without FBTC seizures (FBTCneg group) and 30 with FBTCS (FBTCpos group) recorded during video electroencephalography (VEEG) with respirato... Bilateral amygdala volumes were significantly increased in the FBTCpos cohort compared to healthy controls and the FBTCneg group. Patients with recorded PCCA had the highest increase in bilateral amyg... Individuals with FBTCpos and PCCA show significantly increased amygdala volumes and disrupted architecture bilaterally, with greater changes on the left side. The structural alterations reflected by N...

Detection of spontaneous breathing during an apnea test in a patient with suspected brain death using electrical impedance tomography: a case report.

The apnea test (AT) is a crucial procedure in determining brain death (BD), with detection of spontaneous breathing efforts serving as a key criterion. Numerous national statutes mandate complete disc... This case report presents a 55-year-old morbidly obese male patient with suspected BD due to cerebral hemorrhage undergoing an AT. The AT was performed with continuous electrical impedance tomography ... The findings suggest EIT could enhance the sensitivity and accuracy of detecting spontaneous breathing efforts, providing additional insights into the respiratory status of patients during the AT....

The association of gene polymorphisms of adenosine and dopamine receptors with the response to caffeine citrate treatment in infants with apnea of prematurity: a prospective nested case-control study.

To investigate the potential influence of adenosine and dopamine receptor genes polymorphisms in combination with clinical factors on the response of preterm infants to caffeine citrate treatment in a... A prospective nested case-control study enrolled 221 preterm infants with gestational age < 34 weeks. These infants were divided into the response (n = 160) and the non-response groups (n = 61). 22 si... Preterm infants in the non-response group had lower gestational age, lower birth weight, longer periods of oxygen supplementation and caffeine citrate use, and higher incidence of patent ductus arteri... Adenosine receptor gene and dopamine receptor gene polymorphisms influence caffeine citrate treatment response in AOP. By combining genetic and clinical variables, it is possible to predict the respon...