questionsmedicales.fr
Acides aminés, peptides et protéines
Protéines
Hémoprotéines
Globines
Hémoglobines
Hémoglobines anormales
Hémoglobine C
Hémoglobine C : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Hémoglobine C
Électrophorèse de l'hémoglobine
Hémoglobine C
Tests de laboratoire
Dépistage néonatal
Hémoglobine C
Symptômes
5
Complications
Hémoglobine C
Prévention
5
Complications
Hémoglobine C
Conseils génétiques
Hémoglobine C
Vaccination
Hémoglobine C
Traitements
5
Transfusion sanguine
Hémoglobine C
Hydroxyurée
Hémoglobine C
Thérapie génique
Hémoglobine C
Analgésiques
Hémoglobine C
Complications
5
Complications
Hémoglobine C
Crise vaso-occlusive
Hémoglobine C
Problèmes hépatiques
Hémoglobine C
Surveillance
Hémoglobine C
Facteurs de risque
5
Facteurs de risque
Hémoglobine C
Origine ethnique
Hémoglobine C
Antécédents familiaux
Hémoglobine C
Mode de vie
Hémoglobine C
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"@type": "Question",
"name": "Comment diagnostiquer l'hémoglobine C ?",
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"text": "Un test sanguin spécifique, comme l'électrophorèse de l'hémoglobine, permet de diagnostiquer."
}
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{
"@type": "Question",
"name": "Quels tests sont utilisés pour l'hémoglobine C ?",
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"@type": "Question",
"name": "L'hémoglobine C est-elle héréditaire ?",
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"@type": "Question",
"name": "Quels symptômes indiquent un test pour l'hémoglobine C ?",
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"@type": "Question",
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"@type": "Question",
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"@type": "Question",
"name": "L'hémoglobine C cause-t-elle de l'anémie ?",
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}
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{
"@type": "Question",
"name": "Y a-t-il des complications liées à l'hémoglobine C ?",
"position": 8,
"acceptedAnswer": {
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"text": "Des complications peuvent inclure des crises douloureuses et des infections fréquentes."
}
},
{
"@type": "Question",
"name": "Les symptômes varient-ils selon l'âge ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les symptômes peuvent être plus prononcés chez les enfants et les jeunes adultes."
}
},
{
"@type": "Question",
"name": "L'hémoglobine C provoque-t-elle des douleurs ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des douleurs peuvent survenir en raison de la vaso-occlusion des vaisseaux sanguins."
}
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{
"@type": "Question",
"name": "Peut-on prévenir l'hémoglobine C ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Étant génétique, l'hémoglobine C ne peut pas être prévenue, mais des conseils génétiques aident."
}
},
{
"@type": "Question",
"name": "Le dépistage est-il recommandé ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le dépistage est recommandé pour les personnes à risque, notamment les porteurs."
}
},
{
"@type": "Question",
"name": "Comment éviter les complications ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une bonne hydratation et des soins médicaux réguliers aident à éviter les complications."
}
},
{
"@type": "Question",
"name": "Les conseils génétiques sont-ils utiles ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les conseils génétiques aident les familles à comprendre les risques de transmission."
}
},
{
"@type": "Question",
"name": "Y a-t-il des vaccinations recommandées ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des vaccinations contre certaines infections sont recommandées pour les patients."
}
},
{
"@type": "Question",
"name": "Comment traite-t-on l'hémoglobine C ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le traitement peut inclure des transfusions sanguines et des médicaments pour l'anémie."
}
},
{
"@type": "Question",
"name": "Les transfusions sont-elles nécessaires ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des transfusions peuvent être nécessaires en cas d'anémie sévère ou de complications."
}
},
{
"@type": "Question",
"name": "Y a-t-il des médicaments spécifiques pour l'hémoglobine C ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des médicaments comme l'hydroxyurée peuvent être prescrits pour réduire les crises."
}
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{
"@type": "Question",
"name": "La thérapie génique est-elle une option ?",
"position": 19,
"acceptedAnswer": {
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"text": "La thérapie génique est en recherche, mais pas encore une option standard pour l'hémoglobine C."
}
},
{
"@type": "Question",
"name": "Comment gérer les crises douloureuses ?",
"position": 20,
"acceptedAnswer": {
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"text": "Des analgésiques et une hydratation adéquate aident à gérer les crises douloureuses."
}
},
{
"@type": "Question",
"name": "Quelles sont les complications possibles ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent des infections, des crises douloureuses et des problèmes hépatiques."
}
},
{
"@type": "Question",
"name": "L'hémoglobine C augmente-t-elle le risque d'infections ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les patients ont un risque accru d'infections en raison de l'anémie et de la splénomégalie."
}
},
{
"@type": "Question",
"name": "Y a-t-il un risque de crise vaso-occlusive ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les crises vaso-occlusives peuvent survenir, provoquant des douleurs intenses."
}
},
{
"@type": "Question",
"name": "Les problèmes hépatiques sont-ils fréquents ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des problèmes hépatiques peuvent survenir, surtout en cas de transfusions fréquentes."
}
},
{
"@type": "Question",
"name": "Comment surveiller les complications ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des examens réguliers et des bilans sanguins aident à surveiller les complications."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque de l'hémoglobine C ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent des antécédents familiaux et l'origine ethnique, notamment africaine."
}
},
{
"@type": "Question",
"name": "L'origine ethnique influence-t-elle le risque ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les personnes d'origine africaine ou méditerranéenne sont plus à risque."
}
},
{
"@type": "Question",
"name": "Les antécédents familiaux sont-ils importants ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, avoir des membres de la famille atteints augmente le risque de développer l'hémoglobine C."
}
},
{
"@type": "Question",
"name": "Le mode de vie affecte-t-il le risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un mode de vie sain peut réduire les complications, mais ne prévient pas la condition."
}
},
{
"@type": "Question",
"name": "Les femmes enceintes doivent-elles être testées ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le dépistage est recommandé pour les femmes enceintes à risque d'hémoglobine C."
}
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}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 11/04/2025
Contenu vérifié selon les dernières recommandations médicales
2 publications dans cette catégorie
Affiliations :
Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
1Physical Chemistry of Biosystems, Heidelberg University, Im Neuenheimer Feld 253, 69120 Heidelberg, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
3Department of Infectious Diseases, Parasitology, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
3Department of Infectious Diseases, Parasitology, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
1Physical Chemistry of Biosystems, Heidelberg University, Im Neuenheimer Feld 253, 69120 Heidelberg, Germany.
7Center for Integrative Medicine and Physics, Institute for Advanced Study, Kyoto University, Kyoto, 606-8501 Japan.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Institute of Molecular Virology, Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Institute of Medical Microbiology and Hygiene, Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Institute of Molecular Virology, Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Institute of Molecular Virology, Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Institute of Medical Microbiology and Hygiene, Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Core Facility for Functional Peptidomics, Ulm Peptide Pharmaceuticals (U-PEP), Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Core Facility for Functional Peptidomics, Ulm Peptide Pharmaceuticals (U-PEP), Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Core Unit of Mass Spectrometry and Proteomics, Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Computational Biochemistry, Center of Medical Biotechnology, University of Duisburg-Essen, 45141, Essen, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Max-Planck-Institute for Polymer Research Mainz, 55128, Mainz, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Institute of Medical Microbiology and Hygiene, Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Central Facility for Electron Microscopy, Ulm University, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Institute of Molecular Virology, Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Institute of Medical Microbiology and Hygiene, Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Institute of Molecular Virology, Ulm University Medical Center, 89081, Ulm, Germany. jan.muench@uni-ulm.de.
Core Unit of Mass Spectrometry and Proteomics, Ulm University Medical Center, 89081, Ulm, Germany. jan.muench@uni-ulm.de.
Publications dans "Hémoglobine C" :
BACKGROUND Congenital dislocation of the knee (CDK) is rare and can cause significant distress in the delivery room to parents and to healthcare providers, especially if the latter are unaware of this...
Knee fracture-dislocations are complex injuries; however, there is no universally accepted definition of what constitutes a fracture-dislocation within the Schenck Knee Dislocation (KD) V subcategory....
A series of clinical scenarios encompassing various fracture patterns in association with a bicruciate knee ligament injury was created by a working group of 8 surgeons. Utilizing a modified Delphi te...
There was a 100% response rate for Rounds 1 and 2 and a 96% response rate for Round 3. A total of 11 fracture patterns reached consensus for inclusion: (1) nondisplaced articular fracture of the femur...
Using a modified Delphi technique, this study established consensus for specific fracture patterns to include within or exclude from the Schenck KD V subcategory....
Prognostic Level V . See Instructions for Authors for a complete description of levels of evidence....
Traumatic knee dislocations are complex injuries that can be associated with compromise of the neurovascular structures about the knee....
Various classification systems for knee dislocations exist in the literature but should be used with caution as a prognostic tool because many knee dislocations fit into more than 1 category....
Special populations of knee dislocations, such as obese patients and high-velocity mechanism injuries, require additional caution during the initial evaluation for possible vascular injuries....
Congenital dislocation of the knee is characterised by excessive knee extension or dislocation and anterior subluxation of the proximal tibia, and this disease can occur independently or coexist with ...
We reported a case of a 4-month-old female infant with congenital dislocation of the right knee joint, which presented as flexion deformity since birth. Due to limitations in local medical conditions,...
Early initiation of treatment is generally advised, as nonsurgical methods prove satisfactory for mild cases. However, surgical intervention should be considered in cases with severe stiffness, unresp...
Irreducible knee dislocations (IKD) are rare and can often be missed or misdiagnosed. The incidence of knee dislocation is quoted between 0.01% and 0.2% of all orthopaedic injuries, with up to 4% of t...
A systematic review of the literature was conducted on 1st September 2021 in accordance with the PRISMA guidelines using the online databases Medline and EMBASE. The review was registered prospectivel...
The search strategy identified 60 studies eligible for inclusion, giving a total of 114 cases of IKD. Posterolateral dislocation was most common, seen in 85% of cases. The dimple sign was present in 7...
Based on the findings of this SR we conclude that: the most common type of IKDs are PL dislocations, and the MCL, medial retinaculum and capsule and vastus medialis oblique form the most common struct...
IV....
Multisystem injuries affecting vasculature and nerves can be detrimental sequelae of knee dislocations (KDs). The purpose of this study was to provide an update of the current literature since the con...
A two-author screening process was conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines using the MEDLINE database. Frequency of vascular injury, ...
Nineteen articles were analyzed for a total of 37,087 KDs. Of these, 10.7% sustained vascular injuries and 19.6% sustained nerve injuries. Overall, 62.2% of patients with vascular injury underwent sur...
This review updates our understanding on the clinical implications of KDs including frequency of vascular injury (10.7%), amputation (2.2%), and nerve injuries (19.6%). Compared with prior literature,...
To investigate the diagnostic performance of preoperative MRI in evaluating posterolateral corner (PLC) structures after acute knee dislocation (KD) and determine the correlation of MRI with operative...
Acute knee (femorotibial) dislocations between 2005 and 2020 with preoperative MRI and surgical posterolateral corner repair were identified from a single academic institution. From MRI, integrity was...
Thirty-nine KD cases (19 right) in 39 patients (28 male) were included, with mean age of 33 years. Mechanism of injury was as follows: high energy 52%, low energy 38%, ultra-low energy 10%. LCL was mo...
MRI has high accuracy for detecting tears of posterolateral corner stabilizers in the setting of acute KD. However, for grading structure integrity, the correlation of MRI with surgical findings is va...
• In acute knee dislocation, MRI has high diagnostic accuracy for detecting tears of posterolateral corner (PLC) structures. • Preoperative MRI should be considered by orthopedic surgeons when there i...
A 19-year-old man sustained combined, ipsilateral inferior hip and posterior knee fracture-dislocations secondary to a motor vehicle collision. He underwent immediate closed reduction of the knee and ...
Irreducible inferior femoral head dislocation in combination with a knee dislocation requires thoughtful staging and treatment but can result in satisfactory outcomes....
The literature on the disease burden of knee dislocation is lacking. The aim of the study is to systematically assess the global burden, trends, causes, and influencing factors of knee dislocation....
The incidence and years lived with disability (YLDs) of knee dislocation were assessed globally, as well as at the regional and national levels from 1990 to 2019. Subsequent analyses focused on the ag...
Although the age-standardized incidence and YLDs rate of knee dislocation decreased over the past 30 years, the incidence and YLDs number increased. The disease burden remained higher in males compare...
The disease burden of knee dislocation remains heavy. It is essential to recognize the evolving epidemiology of knee dislocation. Utilizing data-driven assessments can assist in formulating public hea...
The management of unreduced knee dislocations who present late is challenging. The aim of this study was to determine the clinical, radiological, and functional outcomes following open reduction and r...