questionsmedicales.fr
Acides aminés, peptides et protéines
Protéines
Hémoprotéines
Globines
Hémoglobines
Hémoglobines anormales
Hémoglobine C
Hémoglobine C : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Hémoglobine C
Électrophorèse de l'hémoglobine
Hémoglobine C
Tests de laboratoire
Dépistage néonatal
Hémoglobine C
Symptômes
5
Complications
Hémoglobine C
Prévention
5
Complications
Hémoglobine C
Conseils génétiques
Hémoglobine C
Vaccination
Hémoglobine C
Traitements
5
Transfusion sanguine
Hémoglobine C
Hydroxyurée
Hémoglobine C
Thérapie génique
Hémoglobine C
Analgésiques
Hémoglobine C
Complications
5
Complications
Hémoglobine C
Crise vaso-occlusive
Hémoglobine C
Problèmes hépatiques
Hémoglobine C
Surveillance
Hémoglobine C
Facteurs de risque
5
Facteurs de risque
Hémoglobine C
Origine ethnique
Hémoglobine C
Antécédents familiaux
Hémoglobine C
Mode de vie
Hémoglobine C
{
"@context": "https://schema.org",
"@graph": [
{
"@type": "MedicalWebPage",
"name": "Hémoglobine C : Questions médicales les plus fréquentes",
"headline": "Hémoglobine C : Comprendre les symptômes, diagnostics et traitements",
"description": "Guide complet et accessible sur les Hémoglobine C : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.",
"datePublished": "2024-04-16",
"dateModified": "2025-04-11",
"inLanguage": "fr",
"medicalAudience": [
{
"@type": "MedicalAudience",
"name": "Grand public",
"audienceType": "Patient",
"healthCondition": {
"@type": "MedicalCondition",
"name": "Hémoglobine C"
},
"suggestedMinAge": 18,
"suggestedGender": "unisex"
},
{
"@type": "MedicalAudience",
"name": "Médecins",
"audienceType": "Physician",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "France"
}
},
{
"@type": "MedicalAudience",
"name": "Chercheurs",
"audienceType": "Researcher",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "International"
}
}
],
"reviewedBy": {
"@type": "Person",
"name": "Dr Olivier Menir",
"jobTitle": "Expert en Médecine",
"description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale",
"url": "/static/pages/docteur-olivier-menir.html",
"alumniOf": {
"@type": "EducationalOrganization",
"name": "Université Paris Descartes"
}
},
"isPartOf": {
"@type": "MedicalWebPage",
"name": "Hémoglobines anormales",
"url": "https://questionsmedicales.fr/mesh/D006455",
"about": {
"@type": "MedicalCondition",
"name": "Hémoglobines anormales",
"code": {
"@type": "MedicalCode",
"code": "D006455",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "D12.776.422.316.762.426"
}
}
},
"about": {
"@type": "MedicalCondition",
"name": "Hémoglobine C",
"alternateName": "Hemoglobin C",
"code": {
"@type": "MedicalCode",
"code": "D006444",
"codingSystem": "MeSH"
}
},
"author": [
{
"@type": "Person",
"name": "Mei Zhang",
"url": "https://questionsmedicales.fr/author/Mei%20Zhang",
"affiliation": {
"@type": "Organization",
"name": "Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu 610041, China."
}
},
{
"@type": "Person",
"name": "Benjamin Fröhlich",
"url": "https://questionsmedicales.fr/author/Benjamin%20Fr%C3%B6hlich",
"affiliation": {
"@type": "Organization",
"name": "1Physical Chemistry of Biosystems, Heidelberg University, Im Neuenheimer Feld 253, 69120 Heidelberg, Germany."
}
},
{
"@type": "Person",
"name": "Christine Lansche",
"url": "https://questionsmedicales.fr/author/Christine%20Lansche",
"affiliation": {
"@type": "Organization",
"name": "3Department of Infectious Diseases, Parasitology, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany."
}
},
{
"@type": "Person",
"name": "Michael Lanzer",
"url": "https://questionsmedicales.fr/author/Michael%20Lanzer",
"affiliation": {
"@type": "Organization",
"name": "3Department of Infectious Diseases, Parasitology, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany."
}
},
{
"@type": "Person",
"name": "Motomu Tanaka",
"url": "https://questionsmedicales.fr/author/Motomu%20Tanaka",
"affiliation": {
"@type": "Organization",
"name": "1Physical Chemistry of Biosystems, Heidelberg University, Im Neuenheimer Feld 253, 69120 Heidelberg, Germany."
}
}
],
"citation": [
{
"@type": "ScholarlyArticle",
"name": "Effect of Mean Platelet Volume to Platelet Count Ratio on Mortality in Peritoneal Dialysis.",
"datePublished": "2022-11-10",
"url": "https://questionsmedicales.fr/article/36405991",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1155/2022/6922809"
}
},
{
"@type": "ScholarlyArticle",
"name": "Neonatal Thrombocytopenia: Factors Associated With the Platelet Count Increment Following Platelet Transfusion.",
"datePublished": "2023-08-11",
"url": "https://questionsmedicales.fr/article/37572863",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1016/j.jpeds.2023.113666"
}
},
{
"@type": "ScholarlyArticle",
"name": "Effect of platelet count and platelet transfusion on fever duration in patients with febrile neutropenia.",
"datePublished": "2022-07-20",
"url": "https://questionsmedicales.fr/article/35855637",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1080/08880018.2022.2066236"
}
},
{
"@type": "ScholarlyArticle",
"name": "Platelet count, temperature and pH value differentially affect hemostatic and immunomodulatory functions of platelets.",
"datePublished": "2023-01-27",
"url": "https://questionsmedicales.fr/article/36738664",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1016/j.thromres.2023.01.026"
}
},
{
"@type": "ScholarlyArticle",
"name": "Platelet count in preeclampsia: a systematic review and meta-analysis.",
"datePublished": "2023-04-24",
"url": "https://questionsmedicales.fr/article/37098392",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1016/j.ajogmf.2023.100979"
}
}
],
"breadcrumb": {
"@type": "BreadcrumbList",
"itemListElement": [
{
"@type": "ListItem",
"position": 1,
"name": "questionsmedicales.fr",
"item": "https://questionsmedicales.fr"
},
{
"@type": "ListItem",
"position": 2,
"name": "Acides aminés, peptides et protéines",
"item": "https://questionsmedicales.fr/mesh/D000602"
},
{
"@type": "ListItem",
"position": 3,
"name": "Protéines",
"item": "https://questionsmedicales.fr/mesh/D011506"
},
{
"@type": "ListItem",
"position": 4,
"name": "Hémoprotéines",
"item": "https://questionsmedicales.fr/mesh/D006420"
},
{
"@type": "ListItem",
"position": 5,
"name": "Globines",
"item": "https://questionsmedicales.fr/mesh/D005914"
},
{
"@type": "ListItem",
"position": 6,
"name": "Hémoglobines",
"item": "https://questionsmedicales.fr/mesh/D006454"
},
{
"@type": "ListItem",
"position": 7,
"name": "Hémoglobines anormales",
"item": "https://questionsmedicales.fr/mesh/D006455"
},
{
"@type": "ListItem",
"position": 8,
"name": "Hémoglobine C",
"item": "https://questionsmedicales.fr/mesh/D006444"
}
]
}
},
{
"@type": "MedicalWebPage",
"name": "Article complet : Hémoglobine C - Questions et réponses",
"headline": "Questions et réponses médicales fréquentes sur Hémoglobine C",
"description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.",
"datePublished": "2025-05-07",
"inLanguage": "fr",
"hasPart": [
{
"@type": "MedicalWebPage",
"name": "Diagnostic",
"headline": "Diagnostic sur Hémoglobine C",
"description": "Comment diagnostiquer l'hémoglobine C ?\nQuels tests sont utilisés pour l'hémoglobine C ?\nL'hémoglobine C est-elle héréditaire ?\nQuels symptômes indiquent un test pour l'hémoglobine C ?\nPeut-on détecter l'hémoglobine C à la naissance ?",
"url": "https://questionsmedicales.fr/mesh/D006444?mesh_terms=Platelet+Count#section-diagnostic"
},
{
"@type": "MedicalWebPage",
"name": "Symptômes",
"headline": "Symptômes sur Hémoglobine C",
"description": "Quels sont les symptômes de l'hémoglobine C ?\nL'hémoglobine C cause-t-elle de l'anémie ?\nY a-t-il des complications liées à l'hémoglobine C ?\nLes symptômes varient-ils selon l'âge ?\nL'hémoglobine C provoque-t-elle des douleurs ?",
"url": "https://questionsmedicales.fr/mesh/D006444?mesh_terms=Platelet+Count#section-symptômes"
},
{
"@type": "MedicalWebPage",
"name": "Prévention",
"headline": "Prévention sur Hémoglobine C",
"description": "Peut-on prévenir l'hémoglobine C ?\nLe dépistage est-il recommandé ?\nComment éviter les complications ?\nLes conseils génétiques sont-ils utiles ?\nY a-t-il des vaccinations recommandées ?",
"url": "https://questionsmedicales.fr/mesh/D006444?mesh_terms=Platelet+Count#section-prévention"
},
{
"@type": "MedicalWebPage",
"name": "Traitements",
"headline": "Traitements sur Hémoglobine C",
"description": "Comment traite-t-on l'hémoglobine C ?\nLes transfusions sont-elles nécessaires ?\nY a-t-il des médicaments spécifiques pour l'hémoglobine C ?\nLa thérapie génique est-elle une option ?\nComment gérer les crises douloureuses ?",
"url": "https://questionsmedicales.fr/mesh/D006444?mesh_terms=Platelet+Count#section-traitements"
},
{
"@type": "MedicalWebPage",
"name": "Complications",
"headline": "Complications sur Hémoglobine C",
"description": "Quelles sont les complications possibles ?\nL'hémoglobine C augmente-t-elle le risque d'infections ?\nY a-t-il un risque de crise vaso-occlusive ?\nLes problèmes hépatiques sont-ils fréquents ?\nComment surveiller les complications ?",
"url": "https://questionsmedicales.fr/mesh/D006444?mesh_terms=Platelet+Count#section-complications"
},
{
"@type": "MedicalWebPage",
"name": "Facteurs de risque",
"headline": "Facteurs de risque sur Hémoglobine C",
"description": "Quels sont les facteurs de risque de l'hémoglobine C ?\nL'origine ethnique influence-t-elle le risque ?\nLes antécédents familiaux sont-ils importants ?\nLe mode de vie affecte-t-il le risque ?\nLes femmes enceintes doivent-elles être testées ?",
"url": "https://questionsmedicales.fr/mesh/D006444?mesh_terms=Platelet+Count#section-facteurs de risque"
}
]
},
{
"@type": "FAQPage",
"mainEntity": [
{
"@type": "Question",
"name": "Comment diagnostiquer l'hémoglobine C ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un test sanguin spécifique, comme l'électrophorèse de l'hémoglobine, permet de diagnostiquer."
}
},
{
"@type": "Question",
"name": "Quels tests sont utilisés pour l'hémoglobine C ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les tests incluent l'électrophorèse et le dosage de l'hémoglobine C dans le sang."
}
},
{
"@type": "Question",
"name": "L'hémoglobine C est-elle héréditaire ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'hémoglobine C est une condition génétique transmise par les parents."
}
},
{
"@type": "Question",
"name": "Quels symptômes indiquent un test pour l'hémoglobine C ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des symptômes comme l'anémie ou des douleurs abdominales peuvent justifier un test."
}
},
{
"@type": "Question",
"name": "Peut-on détecter l'hémoglobine C à la naissance ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le dépistage néonatal peut inclure des tests pour l'hémoglobine C."
}
},
{
"@type": "Question",
"name": "Quels sont les symptômes de l'hémoglobine C ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes incluent fatigue, jaunisse, et douleurs osseuses ou abdominales."
}
},
{
"@type": "Question",
"name": "L'hémoglobine C cause-t-elle de l'anémie ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'hémoglobine C peut entraîner une anémie due à la destruction des globules rouges."
}
},
{
"@type": "Question",
"name": "Y a-t-il des complications liées à l'hémoglobine C ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications peuvent inclure des crises douloureuses et des infections fréquentes."
}
},
{
"@type": "Question",
"name": "Les symptômes varient-ils selon l'âge ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les symptômes peuvent être plus prononcés chez les enfants et les jeunes adultes."
}
},
{
"@type": "Question",
"name": "L'hémoglobine C provoque-t-elle des douleurs ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des douleurs peuvent survenir en raison de la vaso-occlusion des vaisseaux sanguins."
}
},
{
"@type": "Question",
"name": "Peut-on prévenir l'hémoglobine C ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Étant génétique, l'hémoglobine C ne peut pas être prévenue, mais des conseils génétiques aident."
}
},
{
"@type": "Question",
"name": "Le dépistage est-il recommandé ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le dépistage est recommandé pour les personnes à risque, notamment les porteurs."
}
},
{
"@type": "Question",
"name": "Comment éviter les complications ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une bonne hydratation et des soins médicaux réguliers aident à éviter les complications."
}
},
{
"@type": "Question",
"name": "Les conseils génétiques sont-ils utiles ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les conseils génétiques aident les familles à comprendre les risques de transmission."
}
},
{
"@type": "Question",
"name": "Y a-t-il des vaccinations recommandées ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des vaccinations contre certaines infections sont recommandées pour les patients."
}
},
{
"@type": "Question",
"name": "Comment traite-t-on l'hémoglobine C ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le traitement peut inclure des transfusions sanguines et des médicaments pour l'anémie."
}
},
{
"@type": "Question",
"name": "Les transfusions sont-elles nécessaires ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des transfusions peuvent être nécessaires en cas d'anémie sévère ou de complications."
}
},
{
"@type": "Question",
"name": "Y a-t-il des médicaments spécifiques pour l'hémoglobine C ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des médicaments comme l'hydroxyurée peuvent être prescrits pour réduire les crises."
}
},
{
"@type": "Question",
"name": "La thérapie génique est-elle une option ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "La thérapie génique est en recherche, mais pas encore une option standard pour l'hémoglobine C."
}
},
{
"@type": "Question",
"name": "Comment gérer les crises douloureuses ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des analgésiques et une hydratation adéquate aident à gérer les crises douloureuses."
}
},
{
"@type": "Question",
"name": "Quelles sont les complications possibles ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent des infections, des crises douloureuses et des problèmes hépatiques."
}
},
{
"@type": "Question",
"name": "L'hémoglobine C augmente-t-elle le risque d'infections ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les patients ont un risque accru d'infections en raison de l'anémie et de la splénomégalie."
}
},
{
"@type": "Question",
"name": "Y a-t-il un risque de crise vaso-occlusive ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les crises vaso-occlusives peuvent survenir, provoquant des douleurs intenses."
}
},
{
"@type": "Question",
"name": "Les problèmes hépatiques sont-ils fréquents ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des problèmes hépatiques peuvent survenir, surtout en cas de transfusions fréquentes."
}
},
{
"@type": "Question",
"name": "Comment surveiller les complications ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des examens réguliers et des bilans sanguins aident à surveiller les complications."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque de l'hémoglobine C ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent des antécédents familiaux et l'origine ethnique, notamment africaine."
}
},
{
"@type": "Question",
"name": "L'origine ethnique influence-t-elle le risque ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les personnes d'origine africaine ou méditerranéenne sont plus à risque."
}
},
{
"@type": "Question",
"name": "Les antécédents familiaux sont-ils importants ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, avoir des membres de la famille atteints augmente le risque de développer l'hémoglobine C."
}
},
{
"@type": "Question",
"name": "Le mode de vie affecte-t-il le risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un mode de vie sain peut réduire les complications, mais ne prévient pas la condition."
}
},
{
"@type": "Question",
"name": "Les femmes enceintes doivent-elles être testées ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le dépistage est recommandé pour les femmes enceintes à risque d'hémoglobine C."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 11/04/2025
Contenu vérifié selon les dernières recommandations médicales
2 publications dans cette catégorie
Affiliations :
Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
1Physical Chemistry of Biosystems, Heidelberg University, Im Neuenheimer Feld 253, 69120 Heidelberg, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
3Department of Infectious Diseases, Parasitology, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
3Department of Infectious Diseases, Parasitology, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
1Physical Chemistry of Biosystems, Heidelberg University, Im Neuenheimer Feld 253, 69120 Heidelberg, Germany.
7Center for Integrative Medicine and Physics, Institute for Advanced Study, Kyoto University, Kyoto, 606-8501 Japan.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Institute of Molecular Virology, Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Institute of Medical Microbiology and Hygiene, Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Institute of Molecular Virology, Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Institute of Molecular Virology, Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Institute of Medical Microbiology and Hygiene, Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Core Facility for Functional Peptidomics, Ulm Peptide Pharmaceuticals (U-PEP), Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Core Facility for Functional Peptidomics, Ulm Peptide Pharmaceuticals (U-PEP), Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Core Unit of Mass Spectrometry and Proteomics, Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Computational Biochemistry, Center of Medical Biotechnology, University of Duisburg-Essen, 45141, Essen, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Max-Planck-Institute for Polymer Research Mainz, 55128, Mainz, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Institute of Medical Microbiology and Hygiene, Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Central Facility for Electron Microscopy, Ulm University, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Institute of Molecular Virology, Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Institute of Medical Microbiology and Hygiene, Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Institute of Molecular Virology, Ulm University Medical Center, 89081, Ulm, Germany. jan.muench@uni-ulm.de.
Core Unit of Mass Spectrometry and Proteomics, Ulm University Medical Center, 89081, Ulm, Germany. jan.muench@uni-ulm.de.
Publications dans "Hémoglobine C" :
Mean platelet volume to platelet count ratio (MPV/PC) has been found to be an independent risk factor for mortality in various diseases, including cardiovascular disease, cancer, and hemodialysis. We ...
We conducted a retrospective cohort study at a single center and enrolled 1473 PD patients who were catheterized at our PD center from January 1, 2006, to December 31, 2013. All patients were divided ...
Our results indicated that low MPV/PC level was an independent risk factor for all-cause and CV mortality in PD patients aged less than 60 years....
To understand better those factors relevant to the increment of rise in platelet count following a platelet transfusion among thrombocytopenic neonates....
We reviewed all platelet transfusions over 6 years in our multi-neonatal intensive care unit system. For every platelet transfusion in 8 neonatal centers we recorded: (1) platelet count before and aft...
We evaluated 1797 platelet transfusions administered to 605 neonates (median one/recipient, mean 3, and range 1-52). The increment was not associated with gestational age at birth, postnatal age at tr...
The magnitude of post-transfusion rise was unaffected by most variables we studied. However, the increment was lower in neonates with consumptive thrombocytopenia, after pathogen reduction, with longe...
Platelets play a role in hemostasis, thrombosis, and vascular integrity. They also play a major role in the development of inflammation and the activation of immune responses. They have phagocytic act...
Platelets are primarily recognized for their role in hemostasis, but also regulate immune responses by interacting with leukocytes. Their highly sensitive nature enables platelets to rapidly respond t...
Many studies have reported the association between platelets and preeclampsia. However, sample sizes were small, and their findings were inconsistent. We conducted a systematic review and meta-analysi...
A systematic literature search was performed using Medline, Embase, ScienceDirect, Web of Science, Cochrane Library, NICHD-DASH, LILACS, and Scopus from inception to April 22, 2022....
Observational studies comparing platelet count between women with preeclampsia and normotensive pregnant women were included....
The mean differences with 95% confidence interval in platelet count were calculated. Heterogeneity was assessed using I...
A total of 56 studies comprising 4892 preeclamptic and 9947 normotensive pregnant women were included. Meta-analysis showed that platelet count was significantly lower in women with preeclampsia than ...
This meta-analysis confirmed that platelet count was significantly lower in preeclamptic women, irrespective of severity and presence or absence of associated complications, even before the onset of p...
Megakaryocytes (MKs), a kind of functional hematopoietic stem cell, form platelets to maintain platelet balance through cell differentiation and maturation. In recent years, the incidence of blood dis...
Platelet transfusion is commonly performed in infants to correct severe thrombocytopenia or prevent bleeding. Exploring the associations of platelet transfusion, platelet count (PC), and mean platelet...
To evaluate the associations of platelet transfusion, PC, and MPV with IVH and in-hospital mortality and to explore whether platelet transfusion-associated IVH and mortality risks vary with PC and MPV...
This retrospective cohort study included preterm infants who were transferred to the neonatal intensive care unit on their day of birth and received ventilation during their hospital stay. The study w...
Platelet transfusion, PC, and MPV....
Any grade IVH, severe IVH (grade 3 or 4), and in-hospital mortality....
Among the 1221 preterm infants (731 [59.9%] male; median [IQR] gestational age, 31.0 [29.0-33.0] weeks), 94 (7.7%) received 166 platelet transfusions. After adjustment for potential confounders, plate...
In preterm infants, platelet transfusion, PC, and MPV were associated with mortality, and PC was also associated with any grade IVH and severe IVH. The findings suggest that a lower platelet transfusi...
The familial chylomicronemia syndrome (FCS) is an ultra rare disease caused by lipoprotein lipase (LPL) deficiency associated with potentially lethal acute pancreatitis risk. Thrombocytopenia (platele...
To evaluate post-prandial fluctuations in the platelet count (PLC) and functional defects of hemostasis in FCS....
PLC, functional defects in hemostasis and hematologic variables were measured up-to 5 h after a meal in 6 homozygotes for FCS causing gene variants (HoLPL), 6 heterozygotes for LPL loss-of-function va...
Hourly post-prandial PLC was significantly lower in HoLPL than in controls (P < 0.009). Compared to the other groups, the PLC tended to decrease rapidly (in the first hour) post-meal in HoLPL (P = 0.0...
The PLC decreases post-prandially in FCS (HoLPL), is not associated with changes in functional defects of hemostasis and correlates with the NLR, a marker of acute pancreatitis severity....
This study aimed to evaluate the role of platelet count (PLT) in the prognosis of patients with acute respiratory distress syndrome (ARDS)....
The data were extracted from the Medical Information Mart for Intensive Care database (version 2.2). Patients diagnosed with ARDS according to criteria from Berlin Definition and had the platelet coun...
Overall, the final analysis included 3,207 eligible participants with ARDS. According to the Kaplan-Meier curves for 28-day mortality of PLT, PLT ≤ 100 × 10...
PLT appeared to be an independent predictor of mortality in critically ill patients with ARDS....
Linezolid (LZD) is one of the antibiotics used to treat methicillin-resistant Staphylococcus aureus. In Japan, the dose of LZD is not generally adjusted by renal function or therapeutic drug monitorin...
Fifty-five critically ill patients with existing thrombocytopenia (platelet count < 100 ×103 /μL) who received LZD for five days or more during the period from January 2011 to October 2018 were includ...
Mean (± standard error) platelet count prior to initiation of LZD was 47 ± 4 ×103 /uL, which increased significantly to 86 ± 13 ×103 /uL on day 15 (p<0.01). Median [interquartile range] duration of LZ...
Thrombocytopenia in critically ill patients in the ICU did not worsen after initiation of LZD therapy, and may be considered for the treatment of MRSA in this setting....