questionsmedicales.fr
Acides aminés, peptides et protéines
Protéines
Hémoprotéines
Globines
Hémoglobines
Hémoglobines anormales
Hémoglobine C
Hémoglobine C : Questions médicales fréquentes
Termes MeSH sélectionnés :
Randomized Controlled Trials as Topic
Diagnostic
5
Hémoglobine C
Électrophorèse de l'hémoglobine
Hémoglobine C
Tests de laboratoire
Dépistage néonatal
Hémoglobine C
Symptômes
5
Complications
Hémoglobine C
Prévention
5
Complications
Hémoglobine C
Conseils génétiques
Hémoglobine C
Vaccination
Hémoglobine C
Traitements
5
Transfusion sanguine
Hémoglobine C
Hydroxyurée
Hémoglobine C
Thérapie génique
Hémoglobine C
Analgésiques
Hémoglobine C
Complications
5
Complications
Hémoglobine C
Crise vaso-occlusive
Hémoglobine C
Problèmes hépatiques
Hémoglobine C
Surveillance
Hémoglobine C
Facteurs de risque
5
Facteurs de risque
Hémoglobine C
Origine ethnique
Hémoglobine C
Antécédents familiaux
Hémoglobine C
Mode de vie
Hémoglobine C
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"@type": "Question",
"name": "Comment diagnostiquer l'hémoglobine C ?",
"position": 1,
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"text": "Un test sanguin spécifique, comme l'électrophorèse de l'hémoglobine, permet de diagnostiquer."
}
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"@type": "Question",
"name": "Quels tests sont utilisés pour l'hémoglobine C ?",
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"@type": "Question",
"name": "L'hémoglobine C est-elle héréditaire ?",
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"@type": "Question",
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"@type": "Question",
"name": "Quels sont les symptômes de l'hémoglobine C ?",
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"@type": "Question",
"name": "L'hémoglobine C cause-t-elle de l'anémie ?",
"position": 7,
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}
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{
"@type": "Question",
"name": "Y a-t-il des complications liées à l'hémoglobine C ?",
"position": 8,
"acceptedAnswer": {
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"text": "Des complications peuvent inclure des crises douloureuses et des infections fréquentes."
}
},
{
"@type": "Question",
"name": "Les symptômes varient-ils selon l'âge ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les symptômes peuvent être plus prononcés chez les enfants et les jeunes adultes."
}
},
{
"@type": "Question",
"name": "L'hémoglobine C provoque-t-elle des douleurs ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des douleurs peuvent survenir en raison de la vaso-occlusion des vaisseaux sanguins."
}
},
{
"@type": "Question",
"name": "Peut-on prévenir l'hémoglobine C ?",
"position": 11,
"acceptedAnswer": {
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"text": "Étant génétique, l'hémoglobine C ne peut pas être prévenue, mais des conseils génétiques aident."
}
},
{
"@type": "Question",
"name": "Le dépistage est-il recommandé ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le dépistage est recommandé pour les personnes à risque, notamment les porteurs."
}
},
{
"@type": "Question",
"name": "Comment éviter les complications ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une bonne hydratation et des soins médicaux réguliers aident à éviter les complications."
}
},
{
"@type": "Question",
"name": "Les conseils génétiques sont-ils utiles ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les conseils génétiques aident les familles à comprendre les risques de transmission."
}
},
{
"@type": "Question",
"name": "Y a-t-il des vaccinations recommandées ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des vaccinations contre certaines infections sont recommandées pour les patients."
}
},
{
"@type": "Question",
"name": "Comment traite-t-on l'hémoglobine C ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le traitement peut inclure des transfusions sanguines et des médicaments pour l'anémie."
}
},
{
"@type": "Question",
"name": "Les transfusions sont-elles nécessaires ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des transfusions peuvent être nécessaires en cas d'anémie sévère ou de complications."
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},
{
"@type": "Question",
"name": "Y a-t-il des médicaments spécifiques pour l'hémoglobine C ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des médicaments comme l'hydroxyurée peuvent être prescrits pour réduire les crises."
}
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{
"@type": "Question",
"name": "La thérapie génique est-elle une option ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "La thérapie génique est en recherche, mais pas encore une option standard pour l'hémoglobine C."
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{
"@type": "Question",
"name": "Comment gérer les crises douloureuses ?",
"position": 20,
"acceptedAnswer": {
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"text": "Des analgésiques et une hydratation adéquate aident à gérer les crises douloureuses."
}
},
{
"@type": "Question",
"name": "Quelles sont les complications possibles ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent des infections, des crises douloureuses et des problèmes hépatiques."
}
},
{
"@type": "Question",
"name": "L'hémoglobine C augmente-t-elle le risque d'infections ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les patients ont un risque accru d'infections en raison de l'anémie et de la splénomégalie."
}
},
{
"@type": "Question",
"name": "Y a-t-il un risque de crise vaso-occlusive ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les crises vaso-occlusives peuvent survenir, provoquant des douleurs intenses."
}
},
{
"@type": "Question",
"name": "Les problèmes hépatiques sont-ils fréquents ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des problèmes hépatiques peuvent survenir, surtout en cas de transfusions fréquentes."
}
},
{
"@type": "Question",
"name": "Comment surveiller les complications ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des examens réguliers et des bilans sanguins aident à surveiller les complications."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque de l'hémoglobine C ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent des antécédents familiaux et l'origine ethnique, notamment africaine."
}
},
{
"@type": "Question",
"name": "L'origine ethnique influence-t-elle le risque ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les personnes d'origine africaine ou méditerranéenne sont plus à risque."
}
},
{
"@type": "Question",
"name": "Les antécédents familiaux sont-ils importants ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, avoir des membres de la famille atteints augmente le risque de développer l'hémoglobine C."
}
},
{
"@type": "Question",
"name": "Le mode de vie affecte-t-il le risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un mode de vie sain peut réduire les complications, mais ne prévient pas la condition."
}
},
{
"@type": "Question",
"name": "Les femmes enceintes doivent-elles être testées ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le dépistage est recommandé pour les femmes enceintes à risque d'hémoglobine C."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 11/04/2025
Contenu vérifié selon les dernières recommandations médicales
2 publications dans cette catégorie
Affiliations :
Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
1Physical Chemistry of Biosystems, Heidelberg University, Im Neuenheimer Feld 253, 69120 Heidelberg, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
3Department of Infectious Diseases, Parasitology, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
3Department of Infectious Diseases, Parasitology, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
1Physical Chemistry of Biosystems, Heidelberg University, Im Neuenheimer Feld 253, 69120 Heidelberg, Germany.
7Center for Integrative Medicine and Physics, Institute for Advanced Study, Kyoto University, Kyoto, 606-8501 Japan.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Institute of Molecular Virology, Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Institute of Medical Microbiology and Hygiene, Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Institute of Molecular Virology, Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Institute of Molecular Virology, Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Institute of Medical Microbiology and Hygiene, Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Core Facility for Functional Peptidomics, Ulm Peptide Pharmaceuticals (U-PEP), Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Core Facility for Functional Peptidomics, Ulm Peptide Pharmaceuticals (U-PEP), Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Core Unit of Mass Spectrometry and Proteomics, Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Computational Biochemistry, Center of Medical Biotechnology, University of Duisburg-Essen, 45141, Essen, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Max-Planck-Institute for Polymer Research Mainz, 55128, Mainz, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Institute of Medical Microbiology and Hygiene, Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Central Facility for Electron Microscopy, Ulm University, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Institute of Molecular Virology, Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Institute of Medical Microbiology and Hygiene, Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Institute of Molecular Virology, Ulm University Medical Center, 89081, Ulm, Germany. jan.muench@uni-ulm.de.
Core Unit of Mass Spectrometry and Proteomics, Ulm University Medical Center, 89081, Ulm, Germany. jan.muench@uni-ulm.de.
Publications dans "Hémoglobine C" :
Diquafosol enhances fluid transfer and mucin secretion on ocular surface, which has been suggested as an effective treatment for dry eye disease (DED). The aim of the systematic review and meta-analys...
Relevant randomized controlled trials were obtained via search of electronic including PubMed, Embase, Cochrane Library, and Web of Science. A random-effects model was used to pool the results after i...
A total of nine RCTs involving 1295 patients with DED were included in the meta-analysis. Compared to treatment with 0.1% HA, topical treatment with 3% diquafosol significantly improved the Ocular Sur...
Topical treatment with 3% diquafosol may be more effective than 0.1% HA for patients with DED. However, the long-term efficacy and tolerability of diquafosol still need to be determined....
Narrowband ultraviolet B (NB-UVB) phototherapy is commonly prescribed for patients with moderate-to-severe atopic eczema (AE). The efficacy of NB-UVB, however, has not yet properly been established, a...
A pragmatic, multicenter, PROBE trial will be performed with 1:1 randomization of 316 adult patients with moderate-to-severe AE who have inadequate disease control with topical therapy and who are eli...
The UPDATE trial aims to provide high-quality evidence regarding the (cost-)effectiveness and safety of NB-UVB phototherapy in moderate-to-severe AE patients. Challenges that are addressed in the prot...
ClinicalTrials.gov NCT05704205. Registered on December 8, 2022....
Topical drugs are often used as first-line treatment for dermatological conditions. A within-person design may then be well adapted: it consists of randomizing lesions/body sites rather than patients,...
The aim of this review was to provide a methodological overview of within-person randomized trials (WP-RCTs) in dermatology....
We searched for eligible trials published between 2017 and 2021 in MEDLINE, Embase, and Central in dermatology journals and the 6 highest-impact-factor general medical journals. Two authors selected p...
From 1,034 articles identified, we included 54 WP-RCTs, mainly for acne vulgaris, psoriasis, actinic keratosis, and atopic dermatitis. In most of the trials, patients had only 2 lesions/body sites. In...
Our systematic review highlights that despite the publication of the CONSORT checklist extension for WP-RCTs in 2017, this design is rarely used, and when it is, there are methodological and reporting...
We aim to evaluate the clinical efficacy and safety of using laser and light combined with topical minoxidil for alopecia areata. We searched PubMed, Embase, Web of Science, the Cochrane Library, Chin...
Vulvar lichen sclerosus (LS) is a chronic debilitating inflammatory skin disease. Today, the gold standard is a life-long topical steroid treatment. Alternative options are highly desired. We present ...
We recruited 66 patients, 44 in the laser arm and 22 in the steroid arm. Patients with a physician-administered clinical LS score ≥ 4 were included. Participants received either four laser treatments ...
The findings of this trial have the potential to offer a novel treatment option for LS. The standardized Nd:YAG/Er:YAG laser settings and the treatment regime are presented in this paper....
NCT03926299....
Alopecia areata (AA) is a common autoimmune skin disease. Our study aimed to systematically evaluate the efficacy and safety of compound glycyrrhizin (CG) combined with topical minoxidil therapy in tr...
We searched the PubMed, EMBASE, Cochrane Library, Web of Science, CNKI, Wanfang, and VIP databases. Randomized controlled trials (RCTs) on CG combined with topical minoxidil therapy compared with topi...
11 RCTs and 1189 patients were included. Compared with topical minoxidil therapy alone, CG combined with topical minoxidil therapy was more effective at improving the clinical efficacy (RR = 1.36, 95%...
The current evidence indicates that CG combined with topical minoxidil therapy is effective and safe for AA. However, owing to the suboptimal quality of the included studies, more high-quality and lar...
The purpose was to identify and summarize the existing evidence on the efficacy and safety of the topical application of olive oil for preventing pressure ulcers (PUs). We included only randomized con...
To investigate the clinical efficacy and safety of topical difamilast in mild-to-moderate atopic dermatitis (AD)....
Only randomized controlled trials (RCTs) that compared topical difamilast with vehicle treatment for patients with AD were included. PubMed, Web of Science, Ovid Medline, Cochrane Library, ClinicalTri...
Five studies enrolling a total of 1009 patients with mild-to-moderate AD were identified. Compared with the topical vehicle, topical difamilast was associated with a significantly higher success rate ...
This meta-analysis suggests that topical difamilast is an effective and safe treatment for mild-to-moderate AD....
Melasma is a chronic relapsing skin condition. Laser therapy is a new advancement in treatment. Whether the topical application of tranexamic acid (TXA) increases the efficacy of laser therapy in mela...
Randomized controlled trials are used to estimate the causal effect of a treatment on a health outcome of interest in a patient population. Often the specified treatment in a randomized controlled tri...
We use causal reasoning to explain why randomized controlled trials of biomarker targets can arrive at conflicting or misleading conclusions. We describe four key threats to the validity of trials of ...
We illustrate these findings using evidence from 15 randomized controlled trials of blood pressure targets for management of hypertension. Randomized trials of blood pressure targets exhibit substanti...
Researchers should critically assess meta-analyses of trials of targets for variation in the types, distributions, and off-target effects of therapies studied. Trial investigators should release detai...