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Technologie, industrie et agriculture
Produits manufacturés
Matériaux biomimétiques
Membrane artificielle
Double couche lipidique
Double couche lipidique : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Membrane cellulaire
Microscopie électronique
Fluidité membranaire
Marqueurs fluorescents
Perméabilité membranaire
Protéines
Chromatographie
Lipidomique
Lipidomique
Oxydation lipidique
Symptômes
5
Dysfonction membranaire
Inflammation
Fluidité membranaire
Transport cellulaire
Athérosclérose
Maladies métaboliques
Immunité
Signalisation cellulaire
Prévention
5
Alimentation
Acides gras essentiels
Traitements
5
Antioxydants
Stress oxydatif
Thérapie génique
Maladies génétiques
Complications
5
Maladies cardiovasculaires
Maladies métaboliques
Cancer
Progression tumorale
Sclérose en plaques
Troubles neurologiques
Infections
Agents pathogènes
Défaillance membranaire
Inflammation
Facteurs de risque
5
Facteurs génétiques
Mutations
Alimentation
Graisses saturées
Vieillissement
Rigidité membranaire
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"name": "Quels effets sur la santé sont liés aux membranes ?",
"position": 8,
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"name": "Quels signes cliniques sont associés aux membranes ?",
"position": 9,
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"position": 10,
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"name": "Quels modes de vie favorisent la santé membranaire ?",
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{
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"name": "Comment éviter l'oxydation des membranes ?",
"position": 13,
"acceptedAnswer": {
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}
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"name": "Quels facteurs environnementaux affectent les membranes ?",
"position": 14,
"acceptedAnswer": {
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}
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"@type": "Question",
"name": "Comment le stress influence-t-il la santé membranaire ?",
"position": 15,
"acceptedAnswer": {
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"text": "Le stress chronique peut altérer la composition lipidique des membranes."
}
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{
"@type": "Question",
"name": "Quels traitements ciblent les membranes cellulaires ?",
"position": 16,
"acceptedAnswer": {
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"text": "Des médicaments comme les statines modifient la composition lipidique."
}
},
{
"@type": "Question",
"name": "Comment les lipides peuvent-ils être manipulés ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des techniques de nanomédecine utilisent des liposomes pour délivrer des médicaments."
}
},
{
"@type": "Question",
"name": "Quels suppléments peuvent améliorer la santé membranaire ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les acides gras oméga-3 sont bénéfiques pour la fluidité membranaire."
}
},
{
"@type": "Question",
"name": "Comment les antioxydants aident-ils les membranes ?",
"position": 19,
"acceptedAnswer": {
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"text": "Ils protègent les membranes contre l'oxydation et le stress oxydatif."
}
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{
"@type": "Question",
"name": "Quels traitements sont utilisés pour les maladies membranaires ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des thérapies géniques peuvent corriger des défauts dans les membranes."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec des membranes altérées ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des maladies cardiovasculaires et métaboliques peuvent en résulter."
}
},
{
"@type": "Question",
"name": "Comment les membranes affectent-elles le cancer ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des modifications membranaires peuvent favoriser la progression tumorale."
}
},
{
"@type": "Question",
"name": "Quels troubles neurologiques sont liés aux membranes ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des maladies comme la sclérose en plaques sont associées à des anomalies membranaires."
}
},
{
"@type": "Question",
"name": "Comment les infections impactent-elles les membranes ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les agents pathogènes peuvent perturber l'intégrité des membranes cellulaires."
}
},
{
"@type": "Question",
"name": "Quelles sont les conséquences d'une défaillance membranaire ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une défaillance peut entraîner des troubles métaboliques graves et des inflammations."
}
},
{
"@type": "Question",
"name": "Quels facteurs génétiques influencent la santé membranaire ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des mutations dans les gènes liés aux lipides peuvent affecter la membrane."
}
},
{
"@type": "Question",
"name": "Comment l'alimentation impacte-t-elle les membranes ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation riche en graisses saturées peut altérer la fluidité membranaire."
}
},
{
"@type": "Question",
"name": "Quels comportements augmentent le risque de maladies membranaires ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le tabagisme et la sédentarité sont des comportements à risque."
}
},
{
"@type": "Question",
"name": "Comment l'âge affecte-t-il la santé des membranes ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le vieillissement peut entraîner une rigidité accrue des membranes cellulaires."
}
},
{
"@type": "Question",
"name": "Quels facteurs environnementaux sont des risques pour les membranes ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'exposition à des toxines et à des polluants peut endommager les membranes."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 15/02/2025
Contenu vérifié selon les dernières recommandations médicales
4 publications dans cette catégorie
Affiliations :
Department of Physics , Carnegie Mellon University , Pittsburgh , Pennsylvania 15213 , United States.
Publications dans "Double couche lipidique" :
2 publications dans cette catégorie
Affiliations :
Department of Chemistry, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, South Korea.
Publications dans "Double couche lipidique" :
2 publications dans cette catégorie
Affiliations :
Department of Chemistry, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, South Korea.
Publications dans "Double couche lipidique" :
2 publications dans cette catégorie
Affiliations :
Department of Chemistry, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, South Korea.
Publications dans "Double couche lipidique" :
2 publications dans cette catégorie
Affiliations :
Department of Chemistry, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, South Korea.
Publications dans "Double couche lipidique" :
2 publications dans cette catégorie
Affiliations :
Theory and Bio-Systems, Max Planck Institute of Colloids and Interfaces, 14424 Potsdam, Germany. lipowsky@mpikg.mpg.de.
Publications dans "Double couche lipidique" :
2 publications dans cette catégorie
Affiliations :
Department of Molecular Physiology and Biophysics, University of Fukui Faculty of Medical Sciences.
Publications dans "Double couche lipidique" :
2 publications dans cette catégorie
Affiliations :
Department of Molecular Physiology and Biophysics, University of Fukui Faculty of Medical Sciences; oiki-fki@umin.ac.jp.
Publications dans "Double couche lipidique" :
2 publications dans cette catégorie
Affiliations :
Department of Theory and Bio-Systems, Max Planck Institute of Colloids and Interfaces, Science Park Golm, 14424, Potsdam, Germany.
Publications dans "Double couche lipidique" :
2 publications dans cette catégorie
Affiliations :
Interdisciplinary Nanoscience Center (iNANO), Aarhus University, Aarhus C, DK 8000, Denmark. dong@inano.au.dk.
Publications dans "Double couche lipidique" :
2 publications dans cette catégorie
Affiliations :
Department of Cancer Biology and Pharmacology, University of Illinois College of Medicine, Peoria, IL, United States. Electronic address: zakharel@uic.edu.
Publications dans "Double couche lipidique" :
2 publications dans cette catégorie
Affiliations :
A.N. Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences, 31/5 Leninskiy Prospekt, 119071 Moscow, Russia.
Publications dans "Double couche lipidique" :
2 publications dans cette catégorie
Affiliations :
Department of Mechanical Engineering , University of Maryland , College Park , Maryland 20742 , United States.
Publications dans "Double couche lipidique" :
2 publications dans cette catégorie
Affiliations :
Department of Mechanical Engineering , University of Maryland , College Park , Maryland 20742 , United States.
Publications dans "Double couche lipidique" :
2 publications dans cette catégorie
Affiliations :
Department of Mechanical Engineering , University of Maryland , College Park , Maryland 20742 , United States.
Publications dans "Double couche lipidique" :
2 publications dans cette catégorie
Affiliations :
Laboratory of Molecular Biology , National Cancer Institute, National Institutes of Health , Bethesda , Maryland 20892 , United States.
Publications dans "Double couche lipidique" :
2 publications dans cette catégorie
Affiliations :
Department of Mechanical Engineering , University of Maryland , College Park , Maryland 20742 , United States.
Publications dans "Double couche lipidique" :
2 publications dans cette catégorie
Affiliations :
Department of Chemistry, Lehigh University, Bethlehem, Pennsylvania 18015, United States.
Publications dans "Double couche lipidique" :
2 publications dans cette catégorie
Affiliations :
Institute for Biophysical Chemistry and Centre for Biomolecular Magnetic Resonance, Goethe Universität Frankfurt, 60438, Frankfurt am Main, Germany.
Publications dans "Double couche lipidique" :
2 publications dans cette catégorie
Affiliations :
School of Chemical Engineering, Sungkyunkwan University, Suwon, Republic of Korea. jjackman@skku.edu.
Publications dans "Double couche lipidique" :
Adenosine diphosphate (ADP) ribosylation is an important post-translational modification (PTM) that plays a role in a wide variety of cellular processes. To study the enzymes responsible for the estab...
Recent guidelines regarding acute coronary syndrome (ACS) have advocated for use of prasugrel and ticagrelor over clopidogrel for acute coronary syndrome. However, analyses from multiple databases hav...
Usage of oral anticoagulants (OACs) or adenosine diphosphate inhibitors (ADPi) is known to increase the risk of bleeding. We aimed to investigate the impact of OAC and ADPi therapies on short-term out...
All adult patients hospitalized for TBI in Finland during 2005-2018 were retrospectively studied using a combination of national registries. Usage of pharmacy-purchased OACs and ADPi at the time of TB...
The study population included 57,056 persons (mean age 66 years) of whom 0.9% used direct OACs (DOACs), 7.1% vitamin K antagonists (VKA), and 2.3% ADPi. Patients with VKAs had higher case-fatality tha...
Preinjury use of VKA is associated with increases in short-term mortality and in need for ANOs after TBI. DOACs are associated with lower fatality than VKAs after TBI. ADPi were not independently asso...
This study provides Class II evidence that among adults with TBI, mortality was significantly increased in those using VKAs but not in those using DOACs or ADPi....
Nucleoside polyphosphate (NPP) anions are important for enzymatic activity and should be monitored by scientists in industry and medicine. By elucidating enzyme kinetics and processes, it aids in the ...
However, a discriminative turn-on fluorescent property is exhibited by non-fluorescent p-tertbutylcalix[4]arene modified 1,2,3-triazole containing bis-ruthenium polypyridyl complex (RL) upon the addit...
The calix[4]arene macrocycle's excellent size and binding cone conformation make it a good host-guest interface for the pyrophosphate anion and ADP. The bis-ruthenium polypyridyl complex's connection ...
Metastatic castration-resistant prostate cancer (mCRPC) is a heterogeneous disease with varying clinical and molecular subtypes. Almost one-third of patients have abnormalities in homologous recombina...
To compare radiographic progression-free survival (rPFS), overall survival (OS), and treatment-emergent adverse events (TEAEs) among patients with metastatic castrate-resistant prostate cancer (mCRPC)...
We conducted a systematic review/meta-analysis of all published Phase III randomised controlled trials using EMBASE, MEDLINE, and Cochrane (inception until 6 June 2023). Published full-text manuscript...
Three trials were identified: PROpel, MAGNITUDE, and TALAPRO-2. Compared to placebo/ARAT, the PARPi/ARAT combination was associated with a 35% rPFS improvement in the overall cohort (HR 0.65, 95% CI 0...
The addition of PARPi to ARAT in the first-line mCRPC setting is associated with rPFS benefits across subgroups, with the greatest magnitude of benefit in BRCA1/2m patients. OS benefits remain inconsi...
BRCA1 c.5096G>A (p. Arg1699Gln) (hereinafter BRCA1 R1699Q) is classified as a pathogenic genetic variant despite its lower penetrance of breast and ovarian cancers compared to other BRCA1 variants. Ho...
We present a case of stage IIIc high-grade primary peritoneal cancer in a 69-year-old woman with germline BRCA1 R1699Q variant. She received platinum-containing chemotherapy followed by surgery. Eight...
This is the first report of the clinical outcome of PARP inhibitor and platinum-containing chemotherapy in a patient with a BRCA1 R1699Q variant. Despite BRCA1 mutation and high GIS, used as indicator...
Nucleoside diphosphate kinases (NDPKs) are encoded by...
Several experimental studies have linked adenosine's neuroprotective role in cerebral ischemia. During ischemia, adenosine is formed due to intracellular ATP breakdown into ADP, further when phosphate...
Ion channel activation upon ligand gating triggers a myriad of biological events and, therefore, evolution of ligand gating mechanism is of fundamental importance. TRPM2, a typical ancient ion channel...