questionsmedicales.fr
Acides nucléiques, nucléotides et nucléosides
Nucléotides
Ribonucléotides
Nucléoside diphosphate ose
Adénosine diphosphate ose
Adénosine diphosphate ribose
O-acétyl-ADP-ribose
O-acétyl-ADP-ribose : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Analyse Chromatographique
Spectrométrie de Masse
Tests Biochimiques
Dosage Enzymatique
Échantillons Sanguins
Méthodes de Mesure
Biomarqueurs
Niveaux Biologiques
Dysfonctionnement Cellulaire
Troubles Métaboliques
Symptômes
5
Douleur
Troubles Inflammatoires
Troubles Neurologiques
Études Cliniques
Symptômes Digestifs
Déséquilibres Métaboliques
Système Immunitaire
Réponse Immunitaire
Prévention
5
Mode de Vie Sain
Prévention des Maladies
Exercice Physique
Métabolisme
Suppléments
Consultation Médicale
Traitements
5
Inhibiteurs Enzymatiques
Modulateurs Métaboliques
Médicaments
Voies Métaboliques
Thérapies Alternatives
Suppléments Nutritionnels
Alimentation Équilibrée
Régulation Métabolique
Interventions Chirurgicales
Complications Médicales
Complications
5
Complications Métaboliques
Inflammation
Maladies Chroniques
Diabète
Troubles Cardiovasculaires
Études Épidémiologiques
Santé Mentale
Troubles Associés
Infections
Système Immunitaire
Facteurs de risque
5
Facteurs de Risque
Mode de Vie
Vieillissement
Santé Cellulaire
Mode de Vie Sédentaire
Déséquilibres Métaboliques
Maladies Préexistantes
Diabète
{
"@context": "https://schema.org",
"@graph": [
{
"@type": "MedicalWebPage",
"name": "O-acétyl-ADP-ribose : Questions médicales les plus fréquentes",
"headline": "O-acétyl-ADP-ribose : Comprendre les symptômes, diagnostics et traitements",
"description": "Guide complet et accessible sur les O-acétyl-ADP-ribose : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.",
"datePublished": "2024-03-08",
"dateModified": "2025-03-03",
"inLanguage": "fr",
"medicalAudience": [
{
"@type": "MedicalAudience",
"name": "Grand public",
"audienceType": "Patient",
"healthCondition": {
"@type": "MedicalCondition",
"name": "O-acétyl-ADP-ribose"
},
"suggestedMinAge": 18,
"suggestedGender": "unisex"
},
{
"@type": "MedicalAudience",
"name": "Médecins",
"audienceType": "Physician",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "France"
}
},
{
"@type": "MedicalAudience",
"name": "Chercheurs",
"audienceType": "Researcher",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "International"
}
}
],
"reviewedBy": {
"@type": "Person",
"name": "Dr Olivier Menir",
"jobTitle": "Expert en Médecine",
"description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale",
"url": "/static/pages/docteur-olivier-menir.html",
"alumniOf": {
"@type": "EducationalOrganization",
"name": "Université Paris Descartes"
}
},
"isPartOf": {
"@type": "MedicalWebPage",
"name": "Adénosine diphosphate ribose",
"url": "https://questionsmedicales.fr/mesh/D000246",
"about": {
"@type": "MedicalCondition",
"name": "Adénosine diphosphate ribose",
"code": {
"@type": "MedicalCode",
"code": "D000246",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "D13.695.827.708.070.125"
}
}
},
"about": {
"@type": "MedicalCondition",
"name": "O-acétyl-ADP-ribose",
"alternateName": "O-Acetyl-ADP-Ribose",
"code": {
"@type": "MedicalCode",
"code": "D038961",
"codingSystem": "MeSH"
}
},
"author": [
{
"@type": "Person",
"name": "Anthony K L Leung",
"url": "https://questionsmedicales.fr/author/Anthony%20K%20L%20Leung",
"affiliation": {
"@type": "Organization",
"name": "Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA."
}
},
{
"@type": "Person",
"name": "Morgan Dasovich",
"url": "https://questionsmedicales.fr/author/Morgan%20Dasovich",
"affiliation": {
"@type": "Organization",
"name": "Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA."
}
},
{
"@type": "Person",
"name": "Mohsen Badiee",
"url": "https://questionsmedicales.fr/author/Mohsen%20Badiee",
"affiliation": {
"@type": "Organization",
"name": "Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205."
}
},
{
"@type": "Person",
"name": "Yong Zhang",
"url": "https://questionsmedicales.fr/author/Yong%20Zhang",
"affiliation": {
"@type": "Organization",
"name": "Department of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern California, Los Angeles, California 90089, United States."
}
},
{
"@type": "Person",
"name": "Sua Myong",
"url": "https://questionsmedicales.fr/author/Sua%20Myong",
"affiliation": {
"@type": "Organization",
"name": "Program in Cell, Molecular, Developmental Biology, and Biophysics, Johns Hopkins University, Baltimore, Maryland 21218, United States."
}
}
],
"citation": [
{
"@type": "ScholarlyArticle",
"name": "No Association of Multiple Sclerosis with",
"datePublished": "2023-07-09",
"url": "https://questionsmedicales.fr/article/37511014",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.3390/ijms241411254"
}
},
{
"@type": "ScholarlyArticle",
"name": "Alemtuzumab for multiple sclerosis.",
"datePublished": "2023-06-05",
"url": "https://questionsmedicales.fr/article/37272540",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1002/14651858.CD011203.pub3"
}
},
{
"@type": "ScholarlyArticle",
"name": "[Multiple sclerosis treatments].",
"datePublished": "2023-03-23",
"url": "https://questionsmedicales.fr/article/37037639",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1016/j.soin.2023.02.005"
}
},
{
"@type": "ScholarlyArticle",
"name": "Concurrent diagnoses of Tuberous sclerosis and multiple sclerosis.",
"datePublished": "2023-02-18",
"url": "https://questionsmedicales.fr/article/36863086",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1016/j.msard.2023.104586"
}
},
{
"@type": "ScholarlyArticle",
"name": "Pregnancy and multiple sclerosis: 2022 recommendations from the French multiple sclerosis society.",
"datePublished": "2022-11-01",
"url": "https://questionsmedicales.fr/article/36317497",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1177/13524585221129472"
}
}
],
"breadcrumb": {
"@type": "BreadcrumbList",
"itemListElement": [
{
"@type": "ListItem",
"position": 1,
"name": "questionsmedicales.fr",
"item": "https://questionsmedicales.fr"
},
{
"@type": "ListItem",
"position": 2,
"name": "Acides nucléiques, nucléotides et nucléosides",
"item": "https://questionsmedicales.fr/mesh/D009706"
},
{
"@type": "ListItem",
"position": 3,
"name": "Nucléotides",
"item": "https://questionsmedicales.fr/mesh/D009711"
},
{
"@type": "ListItem",
"position": 4,
"name": "Ribonucléotides",
"item": "https://questionsmedicales.fr/mesh/D012265"
},
{
"@type": "ListItem",
"position": 5,
"name": "Nucléoside diphosphate ose",
"item": "https://questionsmedicales.fr/mesh/D009702"
},
{
"@type": "ListItem",
"position": 6,
"name": "Adénosine diphosphate ose",
"item": "https://questionsmedicales.fr/mesh/D000247"
},
{
"@type": "ListItem",
"position": 7,
"name": "Adénosine diphosphate ribose",
"item": "https://questionsmedicales.fr/mesh/D000246"
},
{
"@type": "ListItem",
"position": 8,
"name": "O-acétyl-ADP-ribose",
"item": "https://questionsmedicales.fr/mesh/D038961"
}
]
}
},
{
"@type": "MedicalWebPage",
"name": "Article complet : O-acétyl-ADP-ribose - Questions et réponses",
"headline": "Questions et réponses médicales fréquentes sur O-acétyl-ADP-ribose",
"description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.",
"datePublished": "2025-05-18",
"inLanguage": "fr",
"hasPart": [
{
"@type": "MedicalWebPage",
"name": "Diagnostic",
"headline": "Diagnostic sur O-acétyl-ADP-ribose",
"description": "Comment détecter l'O-acétyl-ADP-ribose dans les cellules ?\nQuels tests sont utilisés pour évaluer l'O-acétyl-ADP-ribose ?\nL'O-acétyl-ADP-ribose est-il mesurable dans le sang ?\nY a-t-il des biomarqueurs associés à l'O-acétyl-ADP-ribose ?\nQuels sont les indicateurs de dysfonctionnement de l'O-acétyl-ADP-ribose ?",
"url": "https://questionsmedicales.fr/mesh/D038961?mesh_terms=Multiple+Sclerosis#section-diagnostic"
},
{
"@type": "MedicalWebPage",
"name": "Symptômes",
"headline": "Symptômes sur O-acétyl-ADP-ribose",
"description": "Quels symptômes sont liés à des niveaux anormaux d'O-acétyl-ADP-ribose ?\nL'O-acétyl-ADP-ribose provoque-t-il des douleurs ?\nY a-t-il des symptômes neurologiques liés à l'O-acétyl-ADP-ribose ?\nDes symptômes digestifs peuvent-ils être liés à l'O-acétyl-ADP-ribose ?\nL'O-acétyl-ADP-ribose affecte-t-il le système immunitaire ?",
"url": "https://questionsmedicales.fr/mesh/D038961?mesh_terms=Multiple+Sclerosis#section-symptômes"
},
{
"@type": "MedicalWebPage",
"name": "Prévention",
"headline": "Prévention sur O-acétyl-ADP-ribose",
"description": "Comment prévenir les déséquilibres d'O-acétyl-ADP-ribose ?\nY a-t-il des recommandations diététiques pour l'O-acétyl-ADP-ribose ?\nL'exercice physique aide-t-il à réguler l'O-acétyl-ADP-ribose ?\nLe stress influence-t-il l'O-acétyl-ADP-ribose ?\nDes suppléments peuvent-ils prévenir les déséquilibres d'O-acétyl-ADP-ribose ?",
"url": "https://questionsmedicales.fr/mesh/D038961?mesh_terms=Multiple+Sclerosis#section-prévention"
},
{
"@type": "MedicalWebPage",
"name": "Traitements",
"headline": "Traitements sur O-acétyl-ADP-ribose",
"description": "Quels traitements ciblent l'O-acétyl-ADP-ribose ?\nL'O-acétyl-ADP-ribose peut-il être traité par des médicaments ?\nY a-t-il des thérapies alternatives pour l'O-acétyl-ADP-ribose ?\nComment l'alimentation influence-t-elle l'O-acétyl-ADP-ribose ?\nDes interventions chirurgicales sont-elles nécessaires pour l'O-acétyl-ADP-ribose ?",
"url": "https://questionsmedicales.fr/mesh/D038961?mesh_terms=Multiple+Sclerosis#section-traitements"
},
{
"@type": "MedicalWebPage",
"name": "Complications",
"headline": "Complications sur O-acétyl-ADP-ribose",
"description": "Quelles complications peuvent survenir avec l'O-acétyl-ADP-ribose ?\nL'O-acétyl-ADP-ribose est-il lié à des maladies chroniques ?\nDes troubles cardiovasculaires peuvent-ils être liés à l'O-acétyl-ADP-ribose ?\nL'O-acétyl-ADP-ribose peut-il affecter la santé mentale ?\nY a-t-il des risques d'infection liés à l'O-acétyl-ADP-ribose ?",
"url": "https://questionsmedicales.fr/mesh/D038961?mesh_terms=Multiple+Sclerosis#section-complications"
},
{
"@type": "MedicalWebPage",
"name": "Facteurs de risque",
"headline": "Facteurs de risque sur O-acétyl-ADP-ribose",
"description": "Quels facteurs de risque influencent l'O-acétyl-ADP-ribose ?\nL'âge est-il un facteur de risque pour l'O-acétyl-ADP-ribose ?\nLe tabagisme influence-t-il l'O-acétyl-ADP-ribose ?\nLe manque d'exercice est-il un facteur de risque ?\nDes maladies préexistantes augmentent-elles le risque d'O-acétyl-ADP-ribose ?",
"url": "https://questionsmedicales.fr/mesh/D038961?mesh_terms=Multiple+Sclerosis#section-facteurs de risque"
}
]
},
{
"@type": "FAQPage",
"mainEntity": [
{
"@type": "Question",
"name": "Comment détecter l'O-acétyl-ADP-ribose dans les cellules ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des techniques comme la chromatographie et la spectrométrie de masse sont utilisées."
}
},
{
"@type": "Question",
"name": "Quels tests sont utilisés pour évaluer l'O-acétyl-ADP-ribose ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les tests biochimiques et les dosages enzymatiques sont couramment utilisés."
}
},
{
"@type": "Question",
"name": "L'O-acétyl-ADP-ribose est-il mesurable dans le sang ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, il peut être mesuré dans des échantillons sanguins par des méthodes spécifiques."
}
},
{
"@type": "Question",
"name": "Y a-t-il des biomarqueurs associés à l'O-acétyl-ADP-ribose ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des biomarqueurs spécifiques peuvent indiquer des niveaux d'O-acétyl-ADP-ribose."
}
},
{
"@type": "Question",
"name": "Quels sont les indicateurs de dysfonctionnement de l'O-acétyl-ADP-ribose ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des niveaux anormaux peuvent indiquer des troubles métaboliques ou cellulaires."
}
},
{
"@type": "Question",
"name": "Quels symptômes sont liés à des niveaux anormaux d'O-acétyl-ADP-ribose ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des symptômes variés peuvent inclure fatigue, troubles métaboliques et inflammation."
}
},
{
"@type": "Question",
"name": "L'O-acétyl-ADP-ribose provoque-t-il des douleurs ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il peut être associé à des douleurs dues à des troubles métaboliques ou inflammatoires."
}
},
{
"@type": "Question",
"name": "Y a-t-il des symptômes neurologiques liés à l'O-acétyl-ADP-ribose ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des études suggèrent un lien potentiel avec des troubles neurologiques, mais c'est encore à explorer."
}
},
{
"@type": "Question",
"name": "Des symptômes digestifs peuvent-ils être liés à l'O-acétyl-ADP-ribose ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des déséquilibres métaboliques peuvent entraîner des symptômes digestifs."
}
},
{
"@type": "Question",
"name": "L'O-acétyl-ADP-ribose affecte-t-il le système immunitaire ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il peut influencer la réponse immunitaire, entraînant des symptômes d'inflammation."
}
},
{
"@type": "Question",
"name": "Comment prévenir les déséquilibres d'O-acétyl-ADP-ribose ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Maintenir un mode de vie sain et équilibré peut aider à prévenir ces déséquilibres."
}
},
{
"@type": "Question",
"name": "Y a-t-il des recommandations diététiques pour l'O-acétyl-ADP-ribose ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation riche en antioxydants et nutriments peut soutenir la santé cellulaire."
}
},
{
"@type": "Question",
"name": "L'exercice physique aide-t-il à réguler l'O-acétyl-ADP-ribose ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exercice régulier peut améliorer le métabolisme et réguler les niveaux d'O-acétyl-ADP-ribose."
}
},
{
"@type": "Question",
"name": "Le stress influence-t-il l'O-acétyl-ADP-ribose ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le stress chronique peut perturber les niveaux d'O-acétyl-ADP-ribose et affecter la santé."
}
},
{
"@type": "Question",
"name": "Des suppléments peuvent-ils prévenir les déséquilibres d'O-acétyl-ADP-ribose ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certains suppléments peuvent aider, mais il est essentiel de consulter un professionnel de santé."
}
},
{
"@type": "Question",
"name": "Quels traitements ciblent l'O-acétyl-ADP-ribose ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des inhibiteurs enzymatiques et des modulateurs métaboliques sont explorés comme traitements."
}
},
{
"@type": "Question",
"name": "L'O-acétyl-ADP-ribose peut-il être traité par des médicaments ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des recherches sont en cours pour développer des médicaments ciblant ses voies métaboliques."
}
},
{
"@type": "Question",
"name": "Y a-t-il des thérapies alternatives pour l'O-acétyl-ADP-ribose ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines thérapies alternatives, comme les suppléments, sont étudiées mais nécessitent plus de preuves."
}
},
{
"@type": "Question",
"name": "Comment l'alimentation influence-t-elle l'O-acétyl-ADP-ribose ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation équilibrée peut aider à réguler les niveaux d'O-acétyl-ADP-ribose."
}
},
{
"@type": "Question",
"name": "Des interventions chirurgicales sont-elles nécessaires pour l'O-acétyl-ADP-ribose ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "En général, les interventions chirurgicales ne sont pas nécessaires, sauf en cas de complications graves."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec l'O-acétyl-ADP-ribose ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications métaboliques et inflammatoires peuvent survenir en cas de déséquilibre."
}
},
{
"@type": "Question",
"name": "L'O-acétyl-ADP-ribose est-il lié à des maladies chroniques ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des niveaux anormaux peuvent être associés à des maladies chroniques comme le diabète."
}
},
{
"@type": "Question",
"name": "Des troubles cardiovasculaires peuvent-ils être liés à l'O-acétyl-ADP-ribose ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des études suggèrent un lien potentiel entre les déséquilibres et les troubles cardiovasculaires."
}
},
{
"@type": "Question",
"name": "L'O-acétyl-ADP-ribose peut-il affecter la santé mentale ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des recherches indiquent qu'il pourrait influencer la santé mentale et les troubles associés."
}
},
{
"@type": "Question",
"name": "Y a-t-il des risques d'infection liés à l'O-acétyl-ADP-ribose ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des déséquilibres peuvent affaiblir le système immunitaire, augmentant le risque d'infections."
}
},
{
"@type": "Question",
"name": "Quels facteurs de risque influencent l'O-acétyl-ADP-ribose ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des facteurs comme l'alimentation, le stress et le mode de vie peuvent influencer ses niveaux."
}
},
{
"@type": "Question",
"name": "L'âge est-il un facteur de risque pour l'O-acétyl-ADP-ribose ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le vieillissement peut affecter les niveaux d'O-acétyl-ADP-ribose et la santé cellulaire."
}
},
{
"@type": "Question",
"name": "Le tabagisme influence-t-il l'O-acétyl-ADP-ribose ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le tabagisme peut perturber le métabolisme et affecter les niveaux d'O-acétyl-ADP-ribose."
}
},
{
"@type": "Question",
"name": "Le manque d'exercice est-il un facteur de risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un mode de vie sédentaire peut contribuer à des déséquilibres d'O-acétyl-ADP-ribose."
}
},
{
"@type": "Question",
"name": "Des maladies préexistantes augmentent-elles le risque d'O-acétyl-ADP-ribose ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines maladies, comme le diabète, peuvent augmenter le risque de déséquilibres."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 03/03/2025
Contenu vérifié selon les dernières recommandations médicales
10 publications dans cette catégorie
Affiliations :
Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.
McKusick-Nathans Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
5 publications dans cette catégorie
Affiliations :
Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.
Department of Chemistry, Krieger School of Arts and Sciences, Johns Hopkins University, Baltimore, MD 21218, USA.
Publications dans "O-acétyl-ADP-ribose" :
5 publications dans cette catégorie
Affiliations :
Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205.
Publications dans "O-acétyl-ADP-ribose" :
4 publications dans cette catégorie
Affiliations :
Department of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern California, Los Angeles, California 90089, United States.
Department of Chemistry, Dornsife College of Letters, Arts and Sciences, University of Southern California, Los Angeles, California 90089, United States.
Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California 90089, United States.
Research Center for Liver Diseases, University of Southern California, Los Angeles, California 90089, United States.
Publications dans "O-acétyl-ADP-ribose" :
4 publications dans cette catégorie
Affiliations :
Program in Cell, Molecular, Developmental Biology, and Biophysics, Johns Hopkins University, Baltimore, Maryland 21218, United States.
Department of Biophysics, Johns Hopkins University, Baltimore, Maryland 21218, United States.
Physics Frontier Center (Center for the Physics of Living Cells), University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
Publications dans "O-acétyl-ADP-ribose" :
3 publications dans cette catégorie
Affiliations :
Department of Biomedical Sciences, Chung Shan Medical University, Taichung, Taiwan.
Publications dans "O-acétyl-ADP-ribose" :
3 publications dans cette catégorie
Affiliations :
Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan.
Publications dans "O-acétyl-ADP-ribose" :
3 publications dans cette catégorie
Affiliations :
Institute of Molecular and Genomic Medicine, National Health Research Institutes, Miaoli, Taiwan.
Publications dans "O-acétyl-ADP-ribose" :
3 publications dans cette catégorie
Affiliations :
Institute of Molecular and Genomic Medicine, National Health Research Institutes, Miaoli, Taiwan.
Publications dans "O-acétyl-ADP-ribose" :
3 publications dans cette catégorie
Affiliations :
Institute of Molecular and Genomic Medicine, National Health Research Institutes, Miaoli, Taiwan.
Publications dans "O-acétyl-ADP-ribose" :
3 publications dans cette catégorie
Affiliations :
Department of Food Science and Biotechnology, Da-Yeh University, Changhua, Taiwan.
Publications dans "O-acétyl-ADP-ribose" :
3 publications dans cette catégorie
Affiliations :
Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan.
Institute of Molecular and Genomic Medicine, National Health Research Institutes, Miaoli, Taiwan.
Department of Food Science and Biotechnology, Da-Yeh University, Changhua, Taiwan.
Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan.
Guang EM Laboratory, New Taipei, Taiwan.
Publications dans "O-acétyl-ADP-ribose" :
3 publications dans cette catégorie
Affiliations :
Laboratory of Signaling and Gene Regulation, Cecil H. and Ida Green Center for Reproductive Biology Sciences, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Section of Laboratory Research, Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address: Cristel.Camacho@utsouthwestern.edu.
Publications dans "O-acétyl-ADP-ribose" :
3 publications dans cette catégorie
Affiliations :
Department of Neurology, Johns Hopkins University, School of Medicine, Baltimore, MD 21205, USA.
Publications dans "O-acétyl-ADP-ribose" :
3 publications dans cette catégorie
Affiliations :
Department of Neurology, Johns Hopkins University, School of Medicine, Baltimore, MD 21205, USA.
Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University, School of Medicine, Baltimore, MD 21205, USA.
Department of Neuroscience, Johns Hopkins University, School of Medicine, Baltimore, MD 21205, USA.
Publications dans "O-acétyl-ADP-ribose" :
3 publications dans cette catégorie
Affiliations :
Department of Neurology, Johns Hopkins University, School of Medicine, Baltimore, MD 21205, USA.
Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University, School of Medicine, Baltimore, MD 21205, USA.
Department of Neuroscience, Johns Hopkins University, School of Medicine, Baltimore, MD 21205, USA.
Publications dans "O-acétyl-ADP-ribose" :
3 publications dans cette catégorie
Publications dans "O-acétyl-ADP-ribose" :
2 publications dans cette catégorie
Affiliations :
Institute of Molecular Biology, Academia Sinica, Taipei 115, Taiwan.
Publications dans "O-acétyl-ADP-ribose" :
2 publications dans cette catégorie
Affiliations :
Institute of Molecular Biology, Academia Sinica, Taipei 115, Taiwan.
Publications dans "O-acétyl-ADP-ribose" :
2 publications dans cette catégorie
Affiliations :
Molecular Toxicology Group, University of Konstanz, Konstanz, Germany.
Publications dans "O-acétyl-ADP-ribose" :
Multiple Sclerosis (MS) is a common immune-mediated disorder of the central nervous system that affects young adults and is characterized by demyelination and neurodegeneration. Recent studies have as...
Multiple sclerosis (MS) is an autoimmune, T-cell-dependent, inflammatory, demyelinating disease of the central nervous system, with an unpredictable course. Current MS therapies focus on treating and ...
To evaluate the benefits and harms of alemtuzumab alone or associated with other treatments in people with any form of MS....
We used standard, extensive Cochrane search methods. The latest search date was 21 June 2022....
We included randomized controlled trials (RCTs) in adults with any subtype of MS comparing alemtuzumab alone or associated with other medications versus placebo; another active drug; or alemtuzumab in...
We used standard Cochrane methods. Our co-primary outcomes were 1. relapse-free survival, 2. sustained disease progression, and 3. number of participants experiencing at least one adverse event. Our s...
We included three RCTs (1713 participants) comparing intravenous alemtuzumab versus subcutaneous interferon beta-1a for relapsing-remitting MS. Participants were treatment-naive (two studies) or had e...
Compared with interferon beta-1a, alemtuzumab may improve relapse-free survival and sustained disease progression-free survival, and make little to no difference on the proportion of participants with...
The last thirty years have led to the introduction of treatments that reduce the frequency of relapses and slow the progression of multiple sclerosis. They must be prescribed early, chosen according t...
Tuberous sclerosis (TS) is a monogenic disorder which causes disabling neurological symptoms. Similarly, multiple sclerosis (MS) may result in disability, but in contrast, is diagnosed without genetic...
The objective of this study was to develop evidence-based recommendations on pregnancy management for persons with multiple sclerosis (MS)....
MS typically affects young women in their childbearing years. Increasing evidence is available to inform questions raised by MS patients and health professionals about pregnancy issues....
The French Group for Recommendations in Multiple Sclerosis (France4MS) reviewed PubMed and university databases (January 1975 through June 2021). The RAND/UCLA appropriateness method was developed to ...
A strong agreement was reached for all 104 proposed recommendations. They cover diverse topics, such as pregnancy planning, follow-up during pregnancy and postpartum, delivery routes, locoregional ana...
The 2022 recommendations of the French MS society should be helpful to harmonise counselling and treatment practice for pregnancy in persons with MS, allowing for better and individualised choices....
The factor that is most relevant and strongly associated with the clinical course of multiple sclerosis is chronological age. Very young patients exclusively have relapsing remitting disease, whereas ...
Changes in the immune system associated with ageing are known as immunosenescence. This is characterised by a decline in immune response, chronic inflammation and an increased risk of autoimmune disea...
Multiple sclerosis is a chronic inflammatory disease of the central nervous system, caused by an autoimmune reaction. Treatment options have largely increased over the years. In this article, we prese...
The current diagnostic criteria for pediatric onset multiple sclerosis (POMS) are summarized, as well as the evidence for performance of the most recent iteration of McDonald criteria in the pediatric...
There is increasing need for evidence-based data on reproduction for women with multiple sclerosis (MS). First-trimester (first 13 weeks) miscarriages are relatively common in the general population. ...
The Canadian Multiple Sclerosis Pregnancy Study (CANPREG-MS) is a prospective study on women with MS who are pregnant or actively trying to conceive. As far as we are aware, this is the first study on...
There were 208 pregnancies during the study and 36 resulted in first-trimester miscarriage for a rate of 17.31%, within the expected range of 15%-20% for the general population....
CANPREG-MS provides real world data that there does not appear to be an increase in first-trimester miscarriages for women with MS. This information will be helpful to women with MS and their healthca...