questionsmedicales.fr
Phénomènes génétiques
Régulation de l'expression des gènes
Modification traductionnelle des protéines
Maturation post-traductionnelle des protéines
Réponse aux protéines mal repliées
Réponse aux protéines mal repliées : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Réponse aux protéines mal repliées
Stress cellulaire
Biopsie
Analyse protéomique
Imagerie médicale
Complications
Biomarqueurs
Protéines chaperonnes
Antécédents médicaux
Maladies métaboliques
Symptômes
5
Fatigue
Troubles métaboliques
Douleur musculaire
Douleur articulaire
Troubles cognitifs
Céphalée
Métabolisme
Résistance à l'insuline
Nausées
Troubles gastro-intestinaux
Prévention
5
Mode de vie sain
Gestion du stress
Bilan de santé
Prévention
Éducation à la santé
Sensibilisation
Soutien psychologique
Santé mentale
Traitements
5
Thérapies ciblées
Médicaments anti-inflammatoires
Exercice physique
Stress cellulaire
Inhibiteurs de protéase
Médicaments
Thérapie génique
Recherche
Complications
5
Maladies métaboliques
Cancers
Troubles cardiovasculaires
Inflammation
Facteurs de risque
5
Stress oxydatif
Prédispositions génétiques
Vieillissement
Dysfonctionnement
Mode de vie sédentaire
Alimentation
Maladies auto-immunes
Exacerbation
Tabagisme
Stress cellulaire
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"position": 17,
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}
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"name": "Les exercices physiques sont-ils bénéfiques ?",
"position": 18,
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}
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"@type": "Question",
"name": "Des médicaments spécifiques sont-ils prescrits ?",
"position": 19,
"acceptedAnswer": {
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"text": "Des médicaments comme les inhibiteurs de la protéase peuvent être utilisés."
}
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"@type": "Question",
"name": "La thérapie génique est-elle une option ?",
"position": 20,
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"text": "La thérapie génique est en recherche pour corriger des défauts liés à l'UPR."
}
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"@type": "Question",
"name": "Quelles complications peuvent survenir ?",
"position": 21,
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"text": "Des maladies métaboliques, des troubles neurologiques et des cancers peuvent survenir."
}
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"@type": "Question",
"name": "L'UPR peut-elle entraîner des maladies chroniques ?",
"position": 22,
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"text": "Oui, l'UPR est liée à des maladies chroniques comme le diabète et l'obésité."
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{
"@type": "Question",
"name": "Y a-t-il un risque accru de cancer ?",
"position": 23,
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}
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"@type": "Question",
"name": "Des troubles cardiovasculaires sont-ils possibles ?",
"position": 24,
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}
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"@type": "Question",
"name": "L'UPR affecte-t-elle la longévité ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des études suggèrent que l'UPR peut influencer la longévité et la santé globale."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque de l'UPR ?",
"position": 26,
"acceptedAnswer": {
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"text": "Les facteurs incluent le stress oxydatif, l'inflammation et des prédispositions génétiques."
}
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{
"@type": "Question",
"name": "L'âge est-il un facteur de risque ?",
"position": 27,
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"@type": "Question",
"name": "Le mode de vie influence-t-il l'UPR ?",
"position": 28,
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"@type": "Question",
"name": "Les maladies auto-immunes sont-elles un risque ?",
"position": 29,
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Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 08/04/2025
Contenu vérifié selon les dernières recommandations médicales
9 publications dans cette catégorie
Affiliations :
School of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana Monroe, Monroe, LA, USA.
3 publications dans cette catégorie
Affiliations :
School of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana Monroe, Monroe, LA 71201, USA.
Publications dans "Réponse aux protéines mal repliées" :
2 publications dans cette catégorie
Affiliations :
MSU-DOE Plant Research Lab and Plant Biology Department Michigan State University, East Lansing, MI, USA. fb@msu.edu.
Publications dans "Réponse aux protéines mal repliées" :
2 publications dans cette catégorie
Affiliations :
Department of Neuroscience; Institute for Translational Neuroscience, University of Minnesota, Minneapolis, MN, USA.
Publications dans "Réponse aux protéines mal repliées" :
2 publications dans cette catégorie
Affiliations :
School of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana Monroe, Monroe, LA 71201, USA.
Publications dans "Réponse aux protéines mal repliées" :
2 publications dans cette catégorie
Affiliations :
School of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana Monroe, Monroe, LA 71201, USA.
Publications dans "Réponse aux protéines mal repliées" :
2 publications dans cette catégorie
Affiliations :
Department of Biophysics, Graduate School of Science, Kyoto University, Kyoto 606-8502, Japan.
Publications dans "Réponse aux protéines mal repliées" :
2 publications dans cette catégorie
Affiliations :
Department of Orthopedics, University of Colorado Anschutz Medical Campus, 12800 E 19th Ave, Mailstop:8343, Aurora, CO, 80045, USA. Srividhya.Iyer@cuanschutz.edu.
Publications dans "Réponse aux protéines mal repliées" :
2 publications dans cette catégorie
Affiliations :
Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile. chetz@med.uchile.cl.
FONDAP Center for Geroscience Brain Health and Metabolism (GERO), Santiago, Chile. chetz@med.uchile.cl.
Program of Cellular and Molecular Biology, Institute of Biomedical Science, University of Chile, Santiago, Chile. chetz@med.uchile.cl.
Buck Institute for Research on Aging, Novato, CA, USA. chetz@med.uchile.cl.
Publications dans "Réponse aux protéines mal repliées" :
2 publications dans cette catégorie
Affiliations :
Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, Massachusetts 01605.
Publications dans "Réponse aux protéines mal repliées" :
2 publications dans cette catégorie
Affiliations :
Apoptosis Research Centre, School of Natural Sciences, National University of Ireland, Galway, Ireland.
Publications dans "Réponse aux protéines mal repliées" :
2 publications dans cette catégorie
Affiliations :
Apoptosis Research Centre, School of Natural Sciences, National University of Ireland, Galway, Ireland.
Publications dans "Réponse aux protéines mal repliées" :
2 publications dans cette catégorie
Affiliations :
Apoptosis Research Centre, School of Natural Sciences, National University of Ireland, Galway, Ireland.
Publications dans "Réponse aux protéines mal repliées" :
2 publications dans cette catégorie
Affiliations :
Medical Biochemistry and Molecular Biology, Medical Faculty, Saarland University, 66421 Homburg, Germany.
Preclinical Center for Molecular Signaling (PZMS), Medical Faculty, Saarland University, 66421 Homburg, Germany.
Publications dans "Réponse aux protéines mal repliées" :
2 publications dans cette catégorie
Affiliations :
Division of Biological Science, Graduate School of Science and Technology, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, Nara 630-0192, Japan.
Publications dans "Réponse aux protéines mal repliées" :
2 publications dans cette catégorie
Affiliations :
Division of Biological Science, Graduate School of Science and Technology, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, Nara 630-0192, Japan.
Publications dans "Réponse aux protéines mal repliées" :
2 publications dans cette catégorie
Affiliations :
Istituto di Biologia e Biotecnologia Agraria, Consiglio Nazionale delle Ricerche, Milano 20133, Italy.
Publications dans "Réponse aux protéines mal repliées" :
2 publications dans cette catégorie
Affiliations :
Istituto di Biologia e Biotecnologia Agraria, Consiglio Nazionale delle Ricerche, Milano 20133, Italy.
Publications dans "Réponse aux protéines mal repliées" :
1 publication dans cette catégorie
Affiliations :
Department of Biosciences, Durham University, South Road, Durham DH1 3LE, UK.
Biophysical Sciences Institute, Durham University, South Road, Durham DH1 3LE, UK.
Publications dans "Réponse aux protéines mal repliées" :
1 publication dans cette catégorie
Affiliations :
Department of Biosciences, Durham University, South Road, Durham DH1 3LE, UK.
Biophysical Sciences Institute, Durham University, South Road, Durham DH1 3LE, UK.
Publications dans "Réponse aux protéines mal repliées" :
Feedback is information provided to recipients about their behavior, performance, or understanding, the goal of which is to foster recipients' self-awareness, and behavioral reinforcement or change. Y...
Clinicians spend a considerable part of their time while supervising trainees providing feedback. It is generally accepted that feedback can play a major role in subsequent academic performance. Tradi...
Feedback from learners is known to be an important motivator for medical teachers, but it can be de-motivating if delivered poorly, leaving teachers frustrated and uncertain. Research has identified c...
We conducted semi-structured interviews with 16 learners from the MD program at the University of British Columbia. Applying an interpretive description methodology, interviews continued until data su...
Learners articulated well-intentioned goals in relation to upward feedback (e.g., to encourage effective teaching practices). However, conflicting priorities such as protecting one's image created ten...
Our findings offer a nuanced understanding of the complexities that influence learners' approaches to upward feedback when challenges arise. In particular, goal conflicts make it difficult for learner...
For motor learning, the processing of behavioral outcomes is of high significance. The feedback-related negativity (FRN) is an event-related potential, which is often described as a correlate of the r...
Safe and competent patient care depends on physicians recognizing and correcting performance deficiencies. Generating effective insight depends on feedback from credible sources. Unfortunately, physic...
Between October 2018 and May 2020, 30 physicians representing various specialties and career stages were interviewed about their experiences with peer review in the context of regulatory body-mandated...
Perceptions about the learning value of mandated peer review were mixed. Most saw value but felt anxiety about being selected due to being wary of regulatory bodies. Recognizing barriers such percepti...
This study establishes an intriguing and challenging paradox: feedback appears often to not be recognized as feedback when it poses no threat, yet feedback that carries such threat is known to be subo...
In this study, we propose...
This is a time of unprecedented change in healthcare. More physicians are being tasked with stepping into a variety of leadership roles without having received the training needed to be an effective l...
Participants completed a tailored 360-feedback tool to gather input on their leadership skills, then engaged in five bi-weekly leadership coaching sessions. We conducted a post-intervention semi-struc...
Twenty-three primary care physicians at an academic medical center engaged in the 360 leadership coaching study. Participants reported that the intervention yielded valuable benefits in five coaching ...
Combining a tailored 360-feedback tool with a five-session leadership coaching intervention provided physicians with valued support infrastructure for becoming more effective leaders. Physicians descr...
Receiving feedback from different types of assessors (e.g., senior residents, staff supervisors) may impact trainees' perceptions of the quantity and quality of data during entrustable professional ac...
From a database of 2228 EPAs, we calculated the frequency of contribution from three assessor groups. We appraised the quality of 60 procedure-related EPAs completed between July 2019 and March 2020 u...
Residents completed over 60% of EPA assessments. We found no difference in modified-CCERR scores between the three groups. When judging EPA feedback value, residents described a process of weighted de...
Like other recent studies, we found that residents contributed most to procedure-related EPA assessments. To the established list of factors influencing residents' judgements of feedback value, we add...
Feedback is regarded as a key component of formative assessment and one of the elements with the greatest impact on students' academic learning. The present study aimed to evaluate and compare student...
All undergraduate second-year dental students were invited to participate in the dental materials science practical session and were randomly allocated into two groups: Group 1 (feedback) sandwich and...
Sixty-nine students participated in the present study with the majority being females (72.5%) and Chinese (79.7%). Cronbach's alpha analysis suggested removing three Likert-scale items, with the remai...
Although students generally had positive perceptions of both feedback models, they tended to favour the feedback sandwich. Neither gender nor ethnicity affected the students' perceptions of the two fe...
Accessible and efficient opportunities for health professional faculty to hone feedback skills are limited. In addition, feedback models to apply to the objective structured clinical examination (OSCE...
Annually, paediatric interns from Children's National Hospital and Walter Reed National Military Medical Center participate in an OSCE, which includes faculty observation and immediate feedback to tra...
Comparison of the initial evaluation to the post-SOAP Feedback Training Program intervention data using a Wilcoxon signed rank test showed statistically significant improvement in six of eight feedbac...
The SOAP Feedback Training Program is an effective intervention to teach the SOAP feedback model and improve faculty feedback quality in an OSCE setting. It is efficient and low resource, facilitating...