questionsmedicales.fr
Phénomènes génétiques
Régulation de l'expression des gènes
Modification traductionnelle des protéines
Maturation post-traductionnelle des protéines
Réponse aux protéines mal repliées
Réponse aux protéines mal repliées : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Réponse aux protéines mal repliées
Stress cellulaire
Biopsie
Analyse protéomique
Imagerie médicale
Complications
Biomarqueurs
Protéines chaperonnes
Antécédents médicaux
Maladies métaboliques
Symptômes
5
Fatigue
Troubles métaboliques
Douleur musculaire
Douleur articulaire
Troubles cognitifs
Céphalée
Métabolisme
Résistance à l'insuline
Nausées
Troubles gastro-intestinaux
Prévention
5
Mode de vie sain
Gestion du stress
Bilan de santé
Prévention
Éducation à la santé
Sensibilisation
Soutien psychologique
Santé mentale
Traitements
5
Thérapies ciblées
Médicaments anti-inflammatoires
Exercice physique
Stress cellulaire
Inhibiteurs de protéase
Médicaments
Thérapie génique
Recherche
Complications
5
Maladies métaboliques
Cancers
Troubles cardiovasculaires
Inflammation
Facteurs de risque
5
Stress oxydatif
Prédispositions génétiques
Vieillissement
Dysfonctionnement
Mode de vie sédentaire
Alimentation
Maladies auto-immunes
Exacerbation
Tabagisme
Stress cellulaire
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"position": 17,
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}
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"name": "Les exercices physiques sont-ils bénéfiques ?",
"position": 18,
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"@type": "Question",
"name": "Des médicaments spécifiques sont-ils prescrits ?",
"position": 19,
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"text": "Des médicaments comme les inhibiteurs de la protéase peuvent être utilisés."
}
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"@type": "Question",
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"position": 20,
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"text": "La thérapie génique est en recherche pour corriger des défauts liés à l'UPR."
}
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"@type": "Question",
"name": "Quelles complications peuvent survenir ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des maladies métaboliques, des troubles neurologiques et des cancers peuvent survenir."
}
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"@type": "Question",
"name": "L'UPR peut-elle entraîner des maladies chroniques ?",
"position": 22,
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"text": "Oui, l'UPR est liée à des maladies chroniques comme le diabète et l'obésité."
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"@type": "Question",
"name": "Y a-t-il un risque accru de cancer ?",
"position": 23,
"acceptedAnswer": {
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}
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"name": "Des troubles cardiovasculaires sont-ils possibles ?",
"position": 24,
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}
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"@type": "Question",
"name": "L'UPR affecte-t-elle la longévité ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des études suggèrent que l'UPR peut influencer la longévité et la santé globale."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque de l'UPR ?",
"position": 26,
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"text": "Les facteurs incluent le stress oxydatif, l'inflammation et des prédispositions génétiques."
}
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"@type": "Question",
"name": "L'âge est-il un facteur de risque ?",
"position": 27,
"acceptedAnswer": {
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"text": "Oui, le vieillissement augmente le risque de dysfonctionnement de l'UPR."
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{
"@type": "Question",
"name": "Le mode de vie influence-t-il l'UPR ?",
"position": 28,
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"text": "Oui, un mode de vie sédentaire et une mauvaise alimentation augmentent le risque."
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"name": "Les maladies auto-immunes sont-elles un risque ?",
"position": 29,
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Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 08/04/2025
Contenu vérifié selon les dernières recommandations médicales
9 publications dans cette catégorie
Affiliations :
School of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana Monroe, Monroe, LA, USA.
3 publications dans cette catégorie
Affiliations :
School of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana Monroe, Monroe, LA 71201, USA.
Publications dans "Réponse aux protéines mal repliées" :
2 publications dans cette catégorie
Affiliations :
MSU-DOE Plant Research Lab and Plant Biology Department Michigan State University, East Lansing, MI, USA. fb@msu.edu.
Publications dans "Réponse aux protéines mal repliées" :
2 publications dans cette catégorie
Affiliations :
Department of Neuroscience; Institute for Translational Neuroscience, University of Minnesota, Minneapolis, MN, USA.
Publications dans "Réponse aux protéines mal repliées" :
2 publications dans cette catégorie
Affiliations :
School of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana Monroe, Monroe, LA 71201, USA.
Publications dans "Réponse aux protéines mal repliées" :
2 publications dans cette catégorie
Affiliations :
School of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana Monroe, Monroe, LA 71201, USA.
Publications dans "Réponse aux protéines mal repliées" :
2 publications dans cette catégorie
Affiliations :
Department of Biophysics, Graduate School of Science, Kyoto University, Kyoto 606-8502, Japan.
Publications dans "Réponse aux protéines mal repliées" :
2 publications dans cette catégorie
Affiliations :
Department of Orthopedics, University of Colorado Anschutz Medical Campus, 12800 E 19th Ave, Mailstop:8343, Aurora, CO, 80045, USA. Srividhya.Iyer@cuanschutz.edu.
Publications dans "Réponse aux protéines mal repliées" :
2 publications dans cette catégorie
Affiliations :
Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile. chetz@med.uchile.cl.
FONDAP Center for Geroscience Brain Health and Metabolism (GERO), Santiago, Chile. chetz@med.uchile.cl.
Program of Cellular and Molecular Biology, Institute of Biomedical Science, University of Chile, Santiago, Chile. chetz@med.uchile.cl.
Buck Institute for Research on Aging, Novato, CA, USA. chetz@med.uchile.cl.
Publications dans "Réponse aux protéines mal repliées" :
2 publications dans cette catégorie
Affiliations :
Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, Massachusetts 01605.
Publications dans "Réponse aux protéines mal repliées" :
2 publications dans cette catégorie
Affiliations :
Apoptosis Research Centre, School of Natural Sciences, National University of Ireland, Galway, Ireland.
Publications dans "Réponse aux protéines mal repliées" :
2 publications dans cette catégorie
Affiliations :
Apoptosis Research Centre, School of Natural Sciences, National University of Ireland, Galway, Ireland.
Publications dans "Réponse aux protéines mal repliées" :
2 publications dans cette catégorie
Affiliations :
Apoptosis Research Centre, School of Natural Sciences, National University of Ireland, Galway, Ireland.
Publications dans "Réponse aux protéines mal repliées" :
2 publications dans cette catégorie
Affiliations :
Medical Biochemistry and Molecular Biology, Medical Faculty, Saarland University, 66421 Homburg, Germany.
Preclinical Center for Molecular Signaling (PZMS), Medical Faculty, Saarland University, 66421 Homburg, Germany.
Publications dans "Réponse aux protéines mal repliées" :
2 publications dans cette catégorie
Affiliations :
Division of Biological Science, Graduate School of Science and Technology, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, Nara 630-0192, Japan.
Publications dans "Réponse aux protéines mal repliées" :
2 publications dans cette catégorie
Affiliations :
Division of Biological Science, Graduate School of Science and Technology, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, Nara 630-0192, Japan.
Publications dans "Réponse aux protéines mal repliées" :
2 publications dans cette catégorie
Affiliations :
Istituto di Biologia e Biotecnologia Agraria, Consiglio Nazionale delle Ricerche, Milano 20133, Italy.
Publications dans "Réponse aux protéines mal repliées" :
2 publications dans cette catégorie
Affiliations :
Istituto di Biologia e Biotecnologia Agraria, Consiglio Nazionale delle Ricerche, Milano 20133, Italy.
Publications dans "Réponse aux protéines mal repliées" :
1 publication dans cette catégorie
Affiliations :
Department of Biosciences, Durham University, South Road, Durham DH1 3LE, UK.
Biophysical Sciences Institute, Durham University, South Road, Durham DH1 3LE, UK.
Publications dans "Réponse aux protéines mal repliées" :
1 publication dans cette catégorie
Affiliations :
Department of Biosciences, Durham University, South Road, Durham DH1 3LE, UK.
Biophysical Sciences Institute, Durham University, South Road, Durham DH1 3LE, UK.
Publications dans "Réponse aux protéines mal repliées" :
Current medical care deeply relies on informatics during all stages of patient care, which is significantly enhanced due to its use. The healthcare professional's formation in medical informatics resu...
A questionnaire was produced with 3 sections and a total of 24 questions. Students replied to the survey before and after taking the medical informatics course....
A total of 719 students from second year of medical and dental school were recruited for the study between the period of September of 2017-May 2018, September 2018-May 2019, September 2019-May 2020, a...
Medical and dental students find medical informatics learning useful for their future professional practice and feel inclined to use it. However, they feel that Universities need to adapt their progra...
When we think of medical research, one intuitively associates it with the analysis of study data collected for a specific research question or with the secondary use of patient data from routine care....
The purpose of educational recommendations is to assist in establishing courses and programs in a discipline, to further develop existing educational activities in the various nations, and to support ...
The aim of these updated recommendations is to support educators in developing BMHI curricula at different education levels, to identify essential skills and competencies for certification of healthca...
An IMIA taskforce, established in 2017, updated the recommendations. The taskforce included representatives from all IMIA regions, with several having been involved in the development of the previous ...
Recommendations are provided for courses/course tracks in BMHI as part of educational programs in biomedical and health sciences, health information management, and informatics/computer science, as we...
The IMIA recommendations reflect societal changes related to globalization, digitalization, and digital transformation in general and in healthcare specifically, and center on educational needs for th...
The vast and heterogeneous data being constantly generated in clinics can provide great wealth for patients and research alike. The quickly evolving field of medical informatics research has contribut...
We performed a scoping review of informatics core literature about medical practice variation (MPV) as an agile summary of the subject in our field....
The Ovid integrated database was searched between 1946 and 2022 to identify MPV studies published in major informatics journals and conference proceedings. Two reviewers performed relevance screening,...
A total of 43 articles were included and went through the thematic analysis. About half (n = 21) of the included articles were published in conference proceedings. Five articles reported the effect of...
MPV remains a critical issue in health care, yet most informatics research has been focused on simple tasks such as automating the detection of MPV and assessing compliance to decision-support systems...
Our scoping review found that informatics studies have focused on detecting of MPV, especially variability in treatments and deviation from practice guidelines. Technological advances should promote m...
Vanderbilt University Medical Center has adopted a unified approach to undergraduate and graduate clinical informatics education. Twenty-three learners have completed the course which is designed arou...
Achieving predictive, precise, participatory, preventive, and personalized health (abbreviated as p-Health) requires comprehensive evaluations of an individual's conditions captured by various measure...
Over the past 30 years, the American Medical Informatics Association (AMIA) has played a pivotal role in fostering a collaborative community for professionals in biomedical and health informatics. As ...
To outline the evolution of the FAMIA program and shed light on its origins, development, and impact. This report explores factors that led to the establishment of FAMIA, considerations affecting its ...
The development of FAMIA is examined through a historical lens, encompassing key milestones, discussions, and decisions that shaped the program. Insights into the formation of FAMIA were gathered thro...
The FAMIA program has inducted five classes, totaling 602 fellows. An overview of disciplines, roles, and application pathways for FAMIA members is provided. A comparative analysis with other fellow r...
Now in its sixth year, FAMIA acknowledges the growing influence of applied informatics within health information professionals, recognizing individuals with experience, training, and a commitment to t...
Imaging and Clinical Informatics are domains of biomedical informatics. Imaging Informatics topics are often not covered in depth in most Clinical Informatics fellowships. While dedicated Imaging Info...
We compared published curricula and test content between Clinical and Imaging Informatics fellowship programs. We then highlighted differences between training programs and identified overlapping topi...
Published consensus curricula and topics were extracted for each specialty. Two informaticists compared topics as shared or not shared between specialties. Next, test content outlines were compared fo...
There were 139 Clinical Informatics topics compared with 97 Imaging Informatics topics. Of the 139 Clinical Informatics topics, 115 (83%) were covered in the Imaging Informatics curriculum. Of the 97 ...
Imaging Informatics and Clinical Informatics fellowship programs have some overlap with areas unique to each. Our review may help guide those seeking informatics education and potential certification....
Even if English is the leading language for international communication, it is essential to keep in mind that research runs at the local level by local teams generally communicating in their local/nat...
Therefore, the European Federation for Medical Informatics - Working Group on Health Informatics for Inter-regional Cooperation" has one objective: To develop a multilingual ontology focusing on Healt...
We have developed the Medical Informatics and Digital Health Multilingual Ontology (MIMO). Hosted on the Health Terminology/Ontology Portal (HeTOP), MIMO contains around 1,000 concepts, 460 MeSH Descr...
MIMO is hosted by HeTOP (Health Terminology/Ontology Portal), which integrates 100 terminologies and ontologies in 55 languages. MIMO is freely available online. MIMO is portable to other knowledge pl...