Jennifer Shanklin

Affiliations

Department of Anesthesia, University of Iowa, Iowa City.
now with Allina Health Surgical Specialists, Abbott Northwestern Hospital, Minneapolis, Minnesota.

Publications (48)

A conserved evolutionary mechanism permits Δ9 desaturation of very-long-chain fatty acyl lipids.

The Journal of biological chemistry

Avec: Yuanheng Cai , Xiao-Hong Yu , Jin Chai , Chang-Jun Liu , John Shanklin

Expression of a Bacterial Trehalose-6-phosphate Synthase otsA Increases Oil Accumulation in Plant Seeds and Vegetative Tissues.

Frontiers in plant science

Avec: Zhiyang Zhai , Jantana Keereetaweep , Hui Liu , Regina Feil , John E Lunn , John Shanklin

Intron-mediated enhancement of DIACYLGLYCEROL ACYLTRANSFERASE1 expression in energycane promotes a step change for lipid accumulation in vegetative tissues.

Biotechnology for biofuels and bioproducts

Avec: Viet Dang Cao , Guangbin Luo , Shelby Korynta , Hui Liu , Yuanxue Liang , John Shanklin , Fredy Altpeter

Physiological Functions of Phospholipid: Diacylglycerol Acyltransferases.

Plant & cell physiology

Avec: Saroj Kumar Sah , Jilian Fan , Jantana Blanford , John Shanklin , Changcheng Xu

Divergent evolution of extreme production of variant plant monounsaturated fatty acids.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Lu Gan , Kiyoul Park , Jin Chai , Evan M Updike , Hyojin Kim , Adam Voshall , Sairam Behera , Xiao-Hong Yu , Yuanheng Cai , Chunyu Zhang , Mark A Wilson , Jeffrey P Mower , Etsuko N Moriyama , Chi Zhang , Sireewan Kaewsuwan , Qun Liu , John Shanklin , Edgar B Cahoon

Purple acid phosphatase2 stimulates a futile cycle of lipid synthesis and degradation, and mitigates the negative growth effects of triacylglycerol accumulation in vegetative tissues.

The New phytologist

Avec: Yingqi Cai , Zhiyang Zhai , Jantana Blanford , Hui Liu , Hai Shi , Jorg Schwender , Changcheng Xu , John Shanklin

CYCLIN-DEPENDENT KINASE 8 positively regulates oil synthesis by activating WRINKLED1 transcription.

The New phytologist

Avec: Zhiyang Zhai , Jantana K Blanford , Yingqi Cai , Jing Sun , Hui Liu , Hai Shi , Jorg Schwender , John Shanklin

Plasticity of the Arabidopsis leaf lipidome and proteome in response to pathogen infection and heat stress.

Plant physiology

Avec: Patricia Scholz , Nathan M Doner , Katharina Gutbrod , Cornelia Herrfurth , Philipp Niemeyer , Magdiel S S Lim , Katharina Blersch , Kerstin Schmitt , Oliver Valerius , John Shanklin , Ivo Doe Feussner , Peter Dörmann , Gerhard H Braus , Robert T Mullen , Till Ischebeck

GRIK phosphorylates and activates KIN10 which also promotes its degradation.

Frontiers in plant science

Avec: Jing Sun , Hui Liu , Jantana K Blanford , Yingqi Cai , Zhiyang Zhai , John Shanklin

The Effect of Improving Basic Preventive Measures in the Perioperative Arena on Staphylococcus aureus Transmission and Surgical Site Infections: A Randomized Clinical Trial.

JAMA network open

Avec: Randy W Loftus , Franklin Dexter , Michael J Goodheart , Megan McDonald , John Keech , Nicolas Noiseux , Andrew Pugely , William Sharp , Mel Sharafuddin , W Thomas Lawrence , Mark Fisher , Patrick McGonagill , Jennifer Shanklin , Dionne Skeete , Chad Tracy , Bradley Erickson , Thomas Granchi , Lance Evans , Eli Schmidt , Joshua Godding , Raven Brenneke , Deanna Persons , Alexia Herber , Mark Yeager , Brent Hadder , Jeremiah R Brown

Rhodoxanthin synthase from honeysuckle; a membrane diiron enzyme catalyzes the multistep conversation of β-carotene to rhodoxanthin.

Science advances

Avec: John Royer , John Shanklin , Nathalie Balch-Kenney , Maria Mayorga , Peter Houston , René M de Jong , Jenna McMahon , Lisa Laprade , Paul Blomquist , Timothy Berry , Yuanheng Cai , Katherine LoBuglio , Joshua Trueheart , Bastien Chevreux

Atomistic insight on structure and dynamics of spinach acyl carrier protein with substrate length.

Biophysical journal

Avec: Marcel D Baer , John Shanklin , Simone Raugei

Castor Stearoyl-ACP Desaturase Can Synthesize a Vicinal Diol by Dioxygenase Chemistry.

Plant physiology

Avec: Edward J Whittle , Yuanheng Cai , Jantana Keereetaweep , Jin Chai , Peter H Buist , John Shanklin

Ectopic Expression of

Plants (Basel, Switzerland)

Avec: Zhiyang Zhai , Hui Liu , John Shanklin

The Role of Sugar Signaling in Regulating Plant Fatty Acid Synthesis.

Frontiers in plant science

Avec: Zhiyang Zhai , Jantana Keereetaweep , Hui Liu , Changcheng Xu , John Shanklin

Engineering triacylglycerol accumulation in duckweed (Lemna japonica).

Plant biotechnology journal

Avec: Yuanxue Liang , Xiao-Hong Yu , Sanket Anaokar , Hai Shi , William B Dahl , Yingqi Cai , Guangbin Luo , Jin Chai , Yuanheng Cai , Almudena Mollá-Morales , Fredy Altpeter , Evan Ernst , Jorg Schwender , Robert A Martienssen , John Shanklin

Metabolic engineering of energycane to hyperaccumulate lipids in vegetative biomass.

BMC biotechnology

Avec: Guangbin Luo , Viet Dang Cao , Baskaran Kannan , Hui Liu , John Shanklin , Fredy Altpeter

Hepatitis C virus NS3/4A inhibitors and other drug-like compounds as covalent binders of SARS-CoV-2 main protease.

Scientific reports

Avec: Babak Andi , Desigan Kumaran , Dale F Kreitler , Alexei S Soares , Jantana Keereetaweep , Jean Jakoncic , Edwin O Lazo , Wuxian Shi , Martin R Fuchs , Robert M Sweet , John Shanklin , Paul D Adams , Jurgen G Schmidt , Martha S Head , Sean McSweeney

Genomics of turions from the Greater Duckweed reveal its pathways for dormancy and re-emergence strategy.

The New phytologist

Avec: Buntora Pasaribu , Kenneth Acosta , Anthony Aylward , Yuanxue Liang , Bradley W Abramson , Kelly Colt , Nolan T Hartwick , John Shanklin , Todd P Michael , Eric Lam

Molecular mechanism of trehalose 6-phosphate inhibition of the plant metabolic sensor kinase SnRK1.

Science advances

Avec: Jantana Blanford , Zhiyang Zhai , Marcel D Baer , Gongrui Guo , Hui Liu , Qun Liu , Simone Raugei , John Shanklin

Diversion of Carbon Flux from Sugars to Lipids Improves the Growth of an Arabidopsis Starchless Mutant.

Plants (Basel, Switzerland)

Avec: Jilian Fan , Chao Zhou , Linhui Yu , Ping Li , John Shanklin , Changcheng Xu

Tissue-specific differences in metabolites and transcripts contribute to the heterogeneity of ricinoleic acid accumulation in Ricinus communis L. (castor) seeds.

Metabolomics : Official journal of the Metabolomic Society

Avec: Drew Sturtevant , Trevor B Romsdahl , Xiao-Hong Yu , David J Burks , Rajeev K Azad , John Shanklin , Kent D Chapman

WRINKLED1 Regulates BIOTIN ATTACHMENT DOMAIN-CONTAINING Proteins that Inhibit Fatty Acid Synthesis.

Plant physiology

Avec: Hui Liu , Zhiyang Zhai , Kate Kuczynski , Jantana Keereetaweep , Jorg Schwender , John Shanklin

Biotin attachment domain-containing proteins mediate hydroxy fatty acid-dependent inhibition of acetyl CoA carboxylase.

Plant physiology

Avec: Xiao-Hong Yu , Yuanheng Cai , Jantana Keereetaweep , Kenneth Wei , Jin Chai , Elen Deng , Hui Liu , John Shanklin

Mechanisms and functions of membrane lipid remodeling in plants.

The Plant journal : for cell and molecular biology

Avec: Linhui Yu , Chao Zhou , Jilian Fan , John Shanklin , Changcheng Xu

Structural basis for SARS-CoV-2 envelope protein recognition of human cell junction protein PALS1.

Nature communications

Avec: Jin Chai , Yuanheng Cai , Changxu Pang , Liguo Wang , Sean McSweeney , John Shanklin , Qun Liu

Mobilizing Vacuolar Sugar Increases Vegetative Triacylglycerol Accumulation.

Frontiers in plant science

Avec: Sanket Anaokar , Hui Liu , Jantana Keereetaweep , Zhiyang Zhai , John Shanklin

Microbiome differences in sugarcane and metabolically engineered oilcane accessions and their implications for bioenergy production.

Biotechnology for biofuels and bioproducts

Avec: Jihoon Yang , Thanwalee Sooksa-Nguan , Baskaran Kannan , Sofia Cano-Alfanar , Hui Liu , Angela Kent , John Shanklin , Fredy Altpeter , Adina Howe

Mechanisms of metabolic adaptation in the duckweed Lemna gibba: an integrated metabolic, transcriptomic and flux analysis.

BMC plant biology

Avec: Hai Shi , Evan Ernst , Nicolas Heinzel , Sean McCorkle , Hardy Rolletschek , Ljudmilla Borisjuk , Stefan Ortleb , Robert Martienssen , John Shanklin , Jorg Schwender

Arabidopsis SnRK1 negatively regulates phenylpropanoid metabolism via Kelch domain-containing F-box proteins.

The New phytologist

Avec: Bin Wang , Xianhai Zhao , Yunjun Zhao , John Shanklin , Qiao Zhao , Chang-Jun Liu

Solving a furan fatty acid biosynthesis puzzle.

The Journal of biological chemistry

Avec: Xiao-Hong Yu , John Shanklin

A consensus-based ensemble approach to improve transcriptome assembly.

BMC bioinformatics

Avec: Adam Voshall , Sairam Behera , Xiangjun Li , Xiao-Hong Yu , Kushagra Kapil , Jitender S Deogun , John Shanklin , Edgar B Cahoon , Etsuko N Moriyama

The expression of genes encoding novel Sesame oleosin variants facilitates enhanced triacylglycerol accumulation in Arabidopsis leaves and seeds.

The New phytologist

Avec: Sanket Anaokar , Yuanxue Liang , Xiao-Hong Yu , Yingqi Cai , Yuanheng Cai , John Shanklin

Creating yellow seed Camelina sativa with enhanced oil accumulation by CRISPR-mediated disruption of Transparent Testa 8.

Plant biotechnology journal

Avec: Yuanheng Cai , Yuanxue Liang , Hai Shi , Jodie Cui , Shreyas Prakash , Jianhui Zhang , Sanket Anaokar , Jin Chai , Jorg Schwender , Chaofu Lu , Xiao-Hong Yu , John Shanklin

An expanded role for the transcription factor

Frontiers in plant science

Avec: Cathleen Kuczynski , Sean McCorkle , Jantana Keereetaweep , John Shanklin , Jorg Schwender

Structural basis for enzymatic terminal C-H bond functionalization of alkanes.

Nature structural & molecular biology

Avec: Jin Chai , Gongrui Guo , Sean M McSweeney , John Shanklin , Qun Liu

Predicting Mössbauer Parameters of Nonheme Diiron Complexes with Density Functional Theory.

Inorganic chemistry

Avec: Atiya Banerjee , Qun Liu , John Shanklin , Mehmed Z Ertem

Arabidopsis trigalactosyldiacylglycerol1 mutants reveal a critical role for phosphtidylcholine remodeling in lipid homeostasis.

The Plant journal : for cell and molecular biology

Avec: Jilian Fan , Saroj Kumar Sah , Gabriel Lemes Jorge , Jantana Blanford , Dongling Xie , Linhui Yu , Jay Thelen , John Shanklin , Changcheng Xu

Structural basis for Ca

Nature communications

Avec: Ping Zhu , Xiao-Hong Yu , Cheng Wang , Qingfang Zhang , Wu Liu , Sean McSweeney , John Shanklin , Eric Lam , Qun Liu

Invasive non-native species likely to threaten biodiversity and ecosystems in the Antarctic Peninsula region.

Global change biology

Avec: Kevin A Hughes , Oliver L Pescott , Jodey Peyton , Tim Adriaens , Elizabeth J Cottier-Cook , Gillian Key , Wolfgang Rabitsch , Elena Tricarico , David K A Barnes , Naomi Baxter , Mark Belchier , Denise Blake , Peter Convey , Wayne Dawson , Danielle Frohlich , Lauren M Gardiner , Pablo González-Moreno , Ross James , Christopher Malumphy , Stephanie Martin , Angeliki F Martinou , Dan Minchin , Andrea Monaco , Niall Moore , Simon A Morley , Katherine Ross , Jonathan Shanklin , Katharine Turvey , David Vaughan , Alexander G C Vaux , Victoria Werenkraut , Ian J Winfield , Helen E Roy

Expression of a Lychee

Plant physiology

Avec: Xiao-Hong Yu , Yuanheng Cai , Jin Chai , Jorg Schwender , John Shanklin

Metabolic and functional connections between cytoplasmic and chloroplast triacylglycerol storage.

Progress in lipid research

Avec: Changcheng Xu , Jilian Fan , John Shanklin

Hydrothermal pretreatment for valorization of genetically engineered bioenergy crop for lipid and cellulosic sugar recovery.

Bioresource technology

Avec: Ramkrishna Singh , Hui Liu , John Shanklin , Vijay Singh

Genome-wide bioinformatic analyses predict key host and viral factors in SARS-CoV-2 pathogenesis.

Communications biology

Avec: Mariana G Ferrarini , Avantika Lal , Rita Rebollo , Andreas J Gruber , Andrea Guarracino , Itziar Martinez Gonzalez , Taylor Floyd , Daniel Siqueira de Oliveira , Justin Shanklin , Ethan Beausoleil , Taneli Pusa , Brett E Pickett , Vanessa Aguiar-Pulido

Regioselectivity mechanism of the Thunbergia alata Δ6-16:0-acyl carrier protein desaturase.

Plant physiology

Avec: Jodie E Guy , Yuanheng Cai , Marcel D Baer , Edward Whittle , Jin Chai , Xiao-Hong Yu , Ylva Lindqvist , Simone Raugei , John Shanklin

A toolkit for plant lipid engineering: Surveying the efficacies of lipogenic factors for accumulating specialty lipids.

Frontiers in plant science

Avec: Yingqi Cai , Xiao-Hong Yu , John Shanklin

Structural mechanism of intracellular autoregulation of zinc uptake in ZIP transporters.

Nature communications

Avec: Changxu Pang , Jin Chai , Ping Zhu , John Shanklin , Qun Liu

Towards oilcane: preliminary field evaluation of metabolically engineered sugarcane with hyper-accumulation of triacylglycerol in vegetative tissues.

Molecular breeding : new strategies in plant improvement

Avec: Baskaran Kannan , Hui Liu , John Shanklin , Fredy Altpeter

Réseau de co-auteurs

John Shanklin 45 collaborations

Hui Liu 15 collaborations

Xiao-Hong Yu 13 collaborations

Yuanheng Cai 11 collaborations

Jin Chai 11 collaborations

Zhiyang Zhai 9 collaborations

Jantana Keereetaweep 8 collaborations

Jorg Schwender 8 collaborations

Changcheng Xu 7 collaborations

Qun Liu 7 collaborations

Yingqi Cai 6 collaborations

Yuanxue Liang 5 collaborations

Fredy Altpeter 5 collaborations

Jilian Fan 5 collaborations

Hai Shi 5 collaborations

Jantana Blanford 4 collaborations

Sanket Anaokar 4 collaborations

Guangbin Luo 3 collaborations

Marcel D Baer 3 collaborations

Simone Raugei 3 collaborations

Baskaran Kannan 3 collaborations

Sean McSweeney 3 collaborations

Linhui Yu 3 collaborations

Chang-Jun Liu 2 collaborations

Viet Dang Cao 2 collaborations

Saroj Kumar Sah 2 collaborations

Adam Voshall 2 collaborations

Sairam Behera 2 collaborations

Etsuko N Moriyama 2 collaborations

Edgar B Cahoon 2 collaborations

Jantana K Blanford 2 collaborations

Jing Sun 2 collaborations

Evan Ernst 2 collaborations

Eric Lam 2 collaborations

Gongrui Guo 2 collaborations

Chao Zhou 2 collaborations

Changxu Pang 2 collaborations

Sean McCorkle 2 collaborations

Ping Zhu 2 collaborations

Regina Feil 1 collaboration

John E Lunn 1 collaboration

Shelby Korynta 1 collaboration

Lu Gan 1 collaboration

Kiyoul Park 1 collaboration

Evan M Updike 1 collaboration

Hyojin Kim 1 collaboration

Chunyu Zhang 1 collaboration

Mark A Wilson 1 collaboration

Jeffrey P Mower 1 collaboration

Chi Zhang 1 collaboration

Sireewan Kaewsuwan 1 collaboration

Patricia Scholz 1 collaboration

Nathan M Doner 1 collaboration

Katharina Gutbrod 1 collaboration

Cornelia Herrfurth 1 collaboration

Philipp Niemeyer 1 collaboration

Magdiel S S Lim 1 collaboration

Katharina Blersch 1 collaboration

Kerstin Schmitt 1 collaboration

Oliver Valerius 1 collaboration

Ivo Doe Feussner 1 collaboration

Peter Dörmann 1 collaboration

Gerhard H Braus 1 collaboration

Robert T Mullen 1 collaboration

Till Ischebeck 1 collaboration

Randy W Loftus 1 collaboration

Franklin Dexter 1 collaboration

Michael J Goodheart 1 collaboration

Megan McDonald 1 collaboration

John Keech 1 collaboration

Nicolas Noiseux 1 collaboration

Andrew Pugely 1 collaboration

William Sharp 1 collaboration

Mel Sharafuddin 1 collaboration

W Thomas Lawrence 1 collaboration

Mark Fisher 1 collaboration

Patrick McGonagill 1 collaboration

Dionne Skeete 1 collaboration

Chad Tracy 1 collaboration

Bradley Erickson 1 collaboration

Thomas Granchi 1 collaboration

Lance Evans 1 collaboration

Eli Schmidt 1 collaboration

Joshua Godding 1 collaboration

Raven Brenneke 1 collaboration

Deanna Persons 1 collaboration

Alexia Herber 1 collaboration

Mark Yeager 1 collaboration

Brent Hadder 1 collaboration

Jeremiah R Brown 1 collaboration

John Royer 1 collaboration

Nathalie Balch-Kenney 1 collaboration

Maria Mayorga 1 collaboration

Peter Houston 1 collaboration

René M de Jong 1 collaboration

Jenna McMahon 1 collaboration

Lisa Laprade 1 collaboration

Paul Blomquist 1 collaboration

Timothy Berry 1 collaboration

Katherine LoBuglio 1 collaboration

Joshua Trueheart 1 collaboration

Bastien Chevreux 1 collaboration

Edward J Whittle 1 collaboration

Peter H Buist 1 collaboration

William B Dahl 1 collaboration

Almudena Mollá-Morales 1 collaboration

Robert A Martienssen 1 collaboration

Babak Andi 1 collaboration

Desigan Kumaran 1 collaboration

Dale F Kreitler 1 collaboration

Alexei S Soares 1 collaboration

Jean Jakoncic 1 collaboration

Edwin O Lazo 1 collaboration

Wuxian Shi 1 collaboration

Martin R Fuchs 1 collaboration

Robert M Sweet 1 collaboration

Paul D Adams 1 collaboration

Jurgen G Schmidt 1 collaboration

Martha S Head 1 collaboration

Buntora Pasaribu 1 collaboration

Kenneth Acosta 1 collaboration

Anthony Aylward 1 collaboration

Bradley W Abramson 1 collaboration

Kelly Colt 1 collaboration

Nolan T Hartwick 1 collaboration

Todd P Michael 1 collaboration

Ping Li 1 collaboration

Drew Sturtevant 1 collaboration

Trevor B Romsdahl 1 collaboration

David J Burks 1 collaboration

Rajeev K Azad 1 collaboration

Kent D Chapman 1 collaboration

Kate Kuczynski 1 collaboration

Kenneth Wei 1 collaboration

Elen Deng 1 collaboration

Liguo Wang 1 collaboration

Jihoon Yang 1 collaboration

Thanwalee Sooksa-Nguan 1 collaboration

Sofia Cano-Alfanar 1 collaboration

Angela Kent 1 collaboration

Adina Howe 1 collaboration

Nicolas Heinzel 1 collaboration

Hardy Rolletschek 1 collaboration

Ljudmilla Borisjuk 1 collaboration

Stefan Ortleb 1 collaboration

Robert Martienssen 1 collaboration

Bin Wang 1 collaboration

Xianhai Zhao 1 collaboration

Yunjun Zhao 1 collaboration

Qiao Zhao 1 collaboration

Xiangjun Li 1 collaboration

Kushagra Kapil 1 collaboration

Jitender S Deogun 1 collaboration

Jodie Cui 1 collaboration

Shreyas Prakash 1 collaboration

Jianhui Zhang 1 collaboration

Chaofu Lu 1 collaboration

Cathleen Kuczynski 1 collaboration

Sean M McSweeney 1 collaboration

Atiya Banerjee 1 collaboration

Mehmed Z Ertem 1 collaboration

Gabriel Lemes Jorge 1 collaboration

Dongling Xie 1 collaboration

Jay Thelen 1 collaboration

Cheng Wang 1 collaboration

Qingfang Zhang 1 collaboration

Wu Liu 1 collaboration

Kevin A Hughes 1 collaboration

Oliver L Pescott 1 collaboration

Jodey Peyton 1 collaboration

Tim Adriaens 1 collaboration

Elizabeth J Cottier-Cook 1 collaboration

Gillian Key 1 collaboration

Wolfgang Rabitsch 1 collaboration

Elena Tricarico 1 collaboration

David K A Barnes 1 collaboration

Naomi Baxter 1 collaboration

Mark Belchier 1 collaboration

Denise Blake 1 collaboration

Peter Convey 1 collaboration

Wayne Dawson 1 collaboration

Danielle Frohlich 1 collaboration

Lauren M Gardiner 1 collaboration

Pablo González-Moreno 1 collaboration

Ross James 1 collaboration

Christopher Malumphy 1 collaboration

Stephanie Martin 1 collaboration

Angeliki F Martinou 1 collaboration

Dan Minchin 1 collaboration

Andrea Monaco 1 collaboration

Niall Moore 1 collaboration

Simon A Morley 1 collaboration

Katherine Ross 1 collaboration

Jonathan Shanklin 1 collaboration

Katharine Turvey 1 collaboration

David Vaughan 1 collaboration

Alexander G C Vaux 1 collaboration

Victoria Werenkraut 1 collaboration

Ian J Winfield 1 collaboration

Helen E Roy 1 collaboration

Ramkrishna Singh 1 collaboration

Vijay Singh 1 collaboration

Mariana G Ferrarini 1 collaboration

Avantika Lal 1 collaboration

Rita Rebollo 1 collaboration

Andreas J Gruber 1 collaboration

Andrea Guarracino 1 collaboration

Itziar Martinez Gonzalez 1 collaboration

Taylor Floyd 1 collaboration

Daniel Siqueira de Oliveira 1 collaboration

Justin Shanklin 1 collaboration

Ethan Beausoleil 1 collaboration

Taneli Pusa 1 collaboration

Brett E Pickett 1 collaboration

Vanessa Aguiar-Pulido 1 collaboration

Jodie E Guy 1 collaboration

Edward Whittle 1 collaboration

Ylva Lindqvist 1 collaboration