Karin E Bornfeldt

Affiliations

From the Department of Medicine, University of Washington, Seattle (B.P.D., R.M., T.K., S.A.G., T.V., T.W., K.D.O., K.E.B., A.C., F.K.).

Publications (45)

Hematopoietic Cell-Expressed Endothelial Nitric Oxide Protects the Liver From Insulin Resistance.

Arteriosclerosis, thrombosis, and vascular biology

Avec: Brian P Dick , Ryan McMahan , Taft Knowles , Lev Becker , Sina A Gharib , Tomas Vaisar , Tomasz Wietecha , Kevin D O'Brien , Karin E Bornfeldt , Alan Chait , Francis Kim

TNF-α induces acyl-CoA synthetase 3 to promote lipid droplet formation in human endothelial cells.

Journal of lipid research

Avec: Hye Seung Jung , Masami Shimizu-Albergine , Xia Shen , Farah Kramer , Dan Shao , Anuradha Vivekanandan-Giri , Subramaniam Pennathur , Rong Tian , Jenny E Kanter , Karin E Bornfeldt

Albuminuria, the High-Density Lipoprotein Proteome, and Coronary Artery Calcification in Type 1 Diabetes Mellitus.

Arteriosclerosis, thrombosis, and vascular biology

Avec: Baohai Shao , Leila R Zelnick , Jake Wimberger , Jonathan Himmelfarb , John Brunzell , W Sean Davidson , Janet K Snell-Bergeon , Karin E Bornfeldt , Ian H de Boer , Jay W Heinecke

Triglyceride lowering by omega-3 fatty acids: a mechanism mediated by N-acyl taurines.

The Journal of clinical investigation

Avec: Karin E Bornfeldt

Cardiovascular disease in diabetes, beyond glucose.

Cell metabolism

Avec: Robert H Eckel , Karin E Bornfeldt , Ira J Goldberg

A targeted proteomics method for quantifying plasma apolipoprotein kinetics in individual mice using stable isotope labeling.

Journal of lipid research

Avec: Baohai Shao , Masami Shimizu-Albergine , Farah Kramer , Jenny E Kanter , Jay W Heinecke , Tomas Vaisar , Bettina Mittendorfer , Bruce W Patterson , Karin E Bornfeldt

Intracellular and Intercellular Aspects of Macrophage Immunometabolism in Atherosclerosis.

Circulation research

Avec: Ira Tabas , Karin E Bornfeldt

Apolipoprotein A1 Forms 5/5 and 5/4 Antiparallel Dimers in Human High-density Lipoprotein.

Molecular & cellular proteomics : MCP

Avec: Yi He , Hyun D Song , G M Anantharamaiah , M N Palgunachari , Karin E Bornfeldt , Jere P Segrest , Jay W Heinecke

Association of apolipoprotein C3 with insulin resistance and coronary artery calcium in patients with type 1 diabetes.

Journal of clinical lipidology

Avec: Teresa Buckner , Baohai Shao , Robert H Eckel , Jay W Heinecke , Karin E Bornfeldt , Janet Snell-Bergeon

ADAM17 Boosts Cholesterol Efflux and Downstream Effects of High-Density Lipoprotein on Inflammatory Pathways in Macrophages.

Arteriosclerosis, thrombosis, and vascular biology

Avec: Vishal Kothari , Jingjing Tang , Yi He , Farah Kramer , Jenny E Kanter , Karin E Bornfeldt

Comparison between genetic and pharmaceutical disruption of Ldlr expression for the development of atherosclerosis.

Journal of lipid research

Avec: Diego Gomes , Shari Wang , Leela Goodspeed , Katherine E Turk , Tomasz Wietecha , Yongjun Liu , Karin E Bornfeldt , Kevin D O'Brien , Alan Chait , Laura J den Hartigh

Niacin Increases Atherogenic Proteins in High-Density Lipoprotein of Statin-Treated Subjects.

Arteriosclerosis, thrombosis, and vascular biology

Avec: Graziella E Ronsein , Tomas Vaisar , W Sean Davidson , Karin E Bornfeldt , Jeffrey L Probstfield , Kevin D O'Brien , Xue-Qiao Zhao , Jay W Heinecke

Hematopoietic NLRP3 and AIM2 Inflammasomes Promote Diabetes-Accelerated Atherosclerosis, but Increased Necrosis Is Independent of Pyroptosis.

Diabetes

Avec: Cheng-Chieh Hsu , Trevor P Fidler , Jenny E Kanter , Vishal Kothari , Farah Kramer , Jingjing Tang , Alan R Tall , Karin E Bornfeldt

Imbalance of APOB Lipoproteins and Large HDL in Type 1 Diabetes Drives Atherosclerosis.

Circulation research

Avec: Vishal Kothari , Tse W W Ho , Ainara G Cabodevilla , Yi He , Farah Kramer , Masami Shimizu-Albergine , Jenny E Kanter , Janet Snell-Bergeon , Edward A Fisher , Baohai Shao , Jay W Heinecke , Jacob O Wobbrock , Warren L Lee , Ira J Goldberg , Tomas Vaisar , Karin E Bornfeldt

Hypertriglyceridemia and Atherosclerosis: Using Human Research to Guide Mechanistic Studies in Animal Models.

Frontiers in endocrinology

Avec: Debapriya Basu , Karin E Bornfeldt

CREBH normalizes dyslipidemia and halts atherosclerosis in diabetes by decreasing circulating remnant lipoproteins.

The Journal of clinical investigation

Avec: Masami Shimizu-Albergine , Debapriya Basu , Jenny E Kanter , Farah Kramer , Vishal Kothari , Shelley Barnhart , Carissa Thornock , Adam E Mullick , Noemie Clouet-Foraison , Tomas Vaisar , Jay W Heinecke , Robert A Hegele , Ira J Goldberg , Karin E Bornfeldt

Pulmonary surfactant protein B carried by HDL predicts incident CVD in patients with type 1 diabetes.

Journal of lipid research

Avec: Baohai Shao , Janet K Snell-Bergeon , Laura L Pyle , Katie E Thomas , Ian H de Boer , Vishal Kothari , Jere Segrest , William S Davidson , Karin E Bornfeldt , Jay W Heinecke

High-Density Lipoprotein Particle Concentration and Size Predict Incident Coronary Artery Disease Events in a Cohort With Type 1 Diabetes.

Journal of the American Heart Association

Avec: Tina Costacou , Tomas Vaisar , Rachel G Miller , W Sean Davidson , Jay W Heinecke , Trevor J Orchard , Karin E Bornfeldt

Central androgen action reverses hypothalamic astrogliosis and atherogenic risk factors induced by orchiectomy and high-fat diet feeding in male mice.

American journal of physiology. Endocrinology and metabolism

Avec: Mauricio D Dorfman , Thomas Monfeuga , Susan J Melhorn , Jenny E Kanter , Jeremy M Frey , Rachael D Fasnacht , Anandhakumar Chandran , Emaad Lala , Inmaculada Velasco , Katya B Rubinow , Thomas H Meek , Ellen A Schur , Karin E Bornfeldt , Joshua P Thaler

Quartet of APOCs and the Different Roles They Play in Diabetes.

Arteriosclerosis, thrombosis, and vascular biology

Avec: Cheng-Chieh Hsu , Jenny E Kanter , Vishal Kothari , Karin E Bornfeldt

Inflammasomes and Atherosclerosis: a Mixed Picture.

Circulation research

Avec: Alan R Tall , Karin E Bornfeldt

sTREM2 is a plasma biomarker for human NASH and promotes hepatocyte lipid accumulation.

Hepatology communications

Avec: Vishal Kothari , Christopher Savard , Jingjing Tang , Sum P Lee , Savitha Subramanian , Shari Wang , Laura J den Hartigh , Karin E Bornfeldt , George N Ioannou

Flipped C-Terminal Ends of APOA1 Promote ABCA1-dependent Cholesterol Efflux by Small HDLs.

medRxiv : the preprint server for health sciences

Avec: Yi He , Chiara Pavanello , Patrick M Hutchins , Chongren Tang , Mohsen Pourmousa , Tomas Vaisar , Hyun D Song , Richard W Pastor , Alan T Remaley , Ira J Goldberg , Tina Costacou , W Sean Davidson , Karin E Bornfeldt , Laura Calabresi , Jere P Segrest , Jay W Heinecke

Distinct roles of size-defined HDL subpopulations in cardiovascular disease.

Current opinion in lipidology

Avec: W Sean Davidson , Tomas Vaisar , Jay W Heinecke , Karin E Bornfeldt

High Concentration of Medium-Sized HDL Particles and Enrichment in HDL Paraoxonase 1 Associate With Protection From Vascular Complications in People With Long-standing Type 1 Diabetes.

Diabetes care

Avec: Tomas Vaisar , Jenny E Kanter , Jake Wimberger , Angela D Irwin , John Gauthier , Emily Wolfson , Vanessa Bahnam , I-Hsien Wu , Hetal Shah , Hillary A Keenan , Carla J Greenbaum , George L King , Jay W Heinecke , Karin E Bornfeldt

Growing evidence for a role for acyl-CoA synthetase 1 in immunometabolism.

Journal of leukocyte biology

Avec: Karin E Bornfeldt

Emerging Targets for Cardiovascular Disease Prevention in Diabetes.

Trends in molecular medicine

Avec: Nathan O Stitziel , Jenny E Kanter , Karin E Bornfeldt

JCL roundtable: Lipids and inflammation in atherosclerosis.

Journal of clinical lipidology

Avec: Karin E Bornfeldt , MacRae F Linton , Edward A Fisher , John R Guyton

Low concentrations of medium-sized HDL particles predict incident CVD in chronic kidney disease patients.

Journal of lipid research

Avec: Baohai Shao , Farsad Afshinnia , Anna V Mathew , Graziella E Ronsein , Carissa Thornock , Angela D Irwin , Mayank Kansal , Panduranga S Rao , Mirela Dobre , Sadeer Al-Kindi , Matthew R Weir , Alan Go , Jiang He , Jing Chen , Harold Feldman , Karin E Bornfeldt , Subramaniam Pennathur , Auteur inconnu

Sex differences in the associations of HDL particle concentration and cholesterol efflux capacity with incident coronary artery disease in type 1 diabetes: The RETRO HDLc cohort study.

Journal of clinical lipidology

Avec: Tina Costacou , Rachel G Miller , Karin E Bornfeldt , Jay W Heinecke , Trevor J Orchard , Tomas Vaisar

Apolipoprotein C3: Form begets function.

Journal of lipid research

Avec: Karin E Bornfeldt

HDL Particle Concentration and Size Predict Incident Coronary Artery Disease Events in People with Type 1 Diabetes.

medRxiv : the preprint server for health sciences

Avec: Tina Costacou , Tomas Vaisar , Rachel G Miller , W Sean Davidson , Jay W Heinecke , Trevor J Orchard , Karin E Bornfeldt

Flipped C-Terminal Ends of APOA1 Promote ABCA1-Dependent Cholesterol Efflux by Small HDLs.

Circulation

Changes in the composition and mechanical properties of dentin in mouse models of diabetes.

Dental materials : official publication of the Academy of Dental Materials

Avec: K Tang , S Ceteznik , M Kim , K E Bornfeldt , J E Kanter , H Zhang , D D Arola

Diabetes Impairs Cellular Cholesterol Efflux From ABCA1 to Small HDL Particles.

Circulation research

Avec: Yi He , Graziella E Ronsein , Chongren Tang , Gail P Jarvik , W Sean Davidson , Vishal Kothari , Hyun D Song , Jere P Segrest , Karin E Bornfeldt , Jay W Heinecke

Remnants of the Triglyceride-Rich Lipoproteins, Diabetes, and Cardiovascular Disease.

Diabetes

Avec: Alan Chait , Henry N Ginsberg , Tomas Vaisar , Jay W Heinecke , Ira J Goldberg , Karin E Bornfeldt

A Role of the Heme Degradation Pathway in Shaping Prostate Inflammatory Responses and Lipid Metabolism.

The American journal of pathology

Avec: Lisa Vikström Lilljebjörn , Eva Csizmadia , Andreas Hedblom , Giacomo Canesin , Alireza Kalbasi , Mailin Li , Farah Kramer , Karin E Bornfeldt , Barbara Wegiel

Monocytes and Macrophages as Protagonists in Vascular Complications of Diabetes.

Frontiers in cardiovascular medicine

Avec: Jenny E Kanter , Cheng-Chieh Hsu , Karin E Bornfeldt

Increased apolipoprotein C3 drives cardiovascular risk in type 1 diabetes.

The Journal of clinical investigation

Avec: Jenny E Kanter , Baohai Shao , Farah Kramer , Shelley Barnhart , Masami Shimizu-Albergine , Tomas Vaisar , Mark J Graham , Rosanne M Crooke , Clarence R Manuel , Rebecca A Haeusler , Daniel Mar , Karol Bomsztyk , John E Hokanson , Gregory L Kinney , Janet K Snell-Bergeon , Jay W Heinecke , Karin E Bornfeldt

Anti-Inflammatory Effects of HDL (High-Density Lipoprotein) in Macrophages Predominate Over Proinflammatory Effects in Atherosclerotic Plaques.

Arteriosclerosis, thrombosis, and vascular biology

Avec: Panagiotis Fotakis , Vishal Kothari , David G Thomas , Marit Westerterp , Matthew M Molusky , Elissa Altin , Sandra Abramowicz , Nan Wang , Yi He , Jay W Heinecke , Karin E Bornfeldt , Alan R Tall

Phosphoproteomic Analysis as an Approach for Understanding Molecular Mechanisms of cAMP-Dependent Actions.

Molecular pharmacology

Avec: Joseph A Beavo , Martin Golkowski , Masami Shimizu-Albergine , Michael-Claude Beltejar , Karin E Bornfeldt , Shao-En Ong

Atherosclerosis Regression and Cholesterol Efflux in Hypertriglyceridemic Mice.

Circulation research

Avec: Tatjana Josefs , Debapriya Basu , Tomas Vaisar , Britt Arets , Jenny E Kanter , Lesley-Ann Huggins , Yunying Hu , Jianhua Liu , Noemie Clouet-Foraison , Jay W Heinecke , Karin E Bornfeldt , Ira J Goldberg , Edward A Fisher

Correction: Cardiomyocyte-specific disruption of Cathepsin K protects against doxorubicin-induced cardiotoxicity.

Cell death & disease

Avec: Rui Guo , Yinan Hua , Jun Ren , Karin E Bornfeldt , Sreejayan Nair

Conformational flexibility of apolipoprotein A-I amino- and carboxy-termini is necessary for lipid binding but not cholesterol efflux.

Journal of lipid research

Avec: Shimpi Bedi , Jamie Morris , Amy Shah , Rachel C Hart , W Gray Jerome , Stephen G Aller , Chongren Tang , Tomas Vaisar , Karin E Bornfeldt , Jere P Segrest , Jay W Heinecke , W Sean Davidson

The Remnant Lipoprotein Hypothesis of Diabetes-Associated Cardiovascular Disease.

Arteriosclerosis, thrombosis, and vascular biology

Avec: Karin E Bornfeldt

Réseau de co-auteurs

Jay W Heinecke 21 collaborations

Tomas Vaisar 16 collaborations

Jenny E Kanter 13 collaborations

W Sean Davidson 9 collaborations

Vishal Kothari 9 collaborations

Farah Kramer 8 collaborations

Baohai Shao 7 collaborations

Ira J Goldberg 7 collaborations

Yi He 7 collaborations

Masami Shimizu-Albergine 6 collaborations

Jere P Segrest 5 collaborations

Tina Costacou 5 collaborations

Hyun D Song 4 collaborations

Chongren Tang 4 collaborations

Kevin D O'Brien 3 collaborations

Alan Chait 3 collaborations

Janet K Snell-Bergeon 3 collaborations

Jingjing Tang 3 collaborations

Graziella E Ronsein 3 collaborations

Cheng-Chieh Hsu 3 collaborations

Alan R Tall 3 collaborations

Edward A Fisher 3 collaborations

Debapriya Basu 3 collaborations

Rachel G Miller 3 collaborations

Trevor J Orchard 3 collaborations

Tomasz Wietecha 2 collaborations

Subramaniam Pennathur 2 collaborations

Jake Wimberger 2 collaborations

Ian H de Boer 2 collaborations

Robert H Eckel 2 collaborations

Janet Snell-Bergeon 2 collaborations

Shari Wang 2 collaborations

Laura J den Hartigh 2 collaborations

Shelley Barnhart 2 collaborations

Carissa Thornock 2 collaborations

Noemie Clouet-Foraison 2 collaborations

Chiara Pavanello 2 collaborations

Patrick M Hutchins 2 collaborations

Mohsen Pourmousa 2 collaborations

Richard W Pastor 2 collaborations

Alan T Remaley 2 collaborations

Laura Calabresi 2 collaborations

Angela D Irwin 2 collaborations

Brian P Dick 1 collaboration

Ryan McMahan 1 collaboration

Taft Knowles 1 collaboration

Lev Becker 1 collaboration

Sina A Gharib 1 collaboration

Francis Kim 1 collaboration

Hye Seung Jung 1 collaboration

Xia Shen 1 collaboration

Dan Shao 1 collaboration

Anuradha Vivekanandan-Giri 1 collaboration

Rong Tian 1 collaboration

Leila R Zelnick 1 collaboration

Jonathan Himmelfarb 1 collaboration

John Brunzell 1 collaboration

Bettina Mittendorfer 1 collaboration

Bruce W Patterson 1 collaboration

Ira Tabas 1 collaboration

G M Anantharamaiah 1 collaboration

M N Palgunachari 1 collaboration

Teresa Buckner 1 collaboration

Diego Gomes 1 collaboration

Leela Goodspeed 1 collaboration

Katherine E Turk 1 collaboration

Yongjun Liu 1 collaboration

Jeffrey L Probstfield 1 collaboration

Xue-Qiao Zhao 1 collaboration

Trevor P Fidler 1 collaboration

Tse W W Ho 1 collaboration

Ainara G Cabodevilla 1 collaboration

Jacob O Wobbrock 1 collaboration

Warren L Lee 1 collaboration

Adam E Mullick 1 collaboration

Robert A Hegele 1 collaboration

Laura L Pyle 1 collaboration

Katie E Thomas 1 collaboration

Jere Segrest 1 collaboration

William S Davidson 1 collaboration

Mauricio D Dorfman 1 collaboration

Thomas Monfeuga 1 collaboration

Susan J Melhorn 1 collaboration

Jeremy M Frey 1 collaboration

Rachael D Fasnacht 1 collaboration

Anandhakumar Chandran 1 collaboration

Emaad Lala 1 collaboration

Inmaculada Velasco 1 collaboration

Katya B Rubinow 1 collaboration

Thomas H Meek 1 collaboration

Ellen A Schur 1 collaboration

Joshua P Thaler 1 collaboration

Christopher Savard 1 collaboration

Sum P Lee 1 collaboration

Savitha Subramanian 1 collaboration

George N Ioannou 1 collaboration

John Gauthier 1 collaboration

Emily Wolfson 1 collaboration

Vanessa Bahnam 1 collaboration

I-Hsien Wu 1 collaboration

Hetal Shah 1 collaboration

Hillary A Keenan 1 collaboration

Carla J Greenbaum 1 collaboration

George L King 1 collaboration

Nathan O Stitziel 1 collaboration

MacRae F Linton 1 collaboration

John R Guyton 1 collaboration

Farsad Afshinnia 1 collaboration

Anna V Mathew 1 collaboration

Mayank Kansal 1 collaboration

Panduranga S Rao 1 collaboration

Mirela Dobre 1 collaboration

Sadeer Al-Kindi 1 collaboration

Matthew R Weir 1 collaboration

Alan Go 1 collaboration

Jiang He 1 collaboration

Jing Chen 1 collaboration

Harold Feldman 1 collaboration

None None 1 collaboration

K Tang 1 collaboration

S Ceteznik 1 collaboration

M Kim 1 collaboration

K E Bornfeldt 1 collaboration

J E Kanter 1 collaboration

H Zhang 1 collaboration

D D Arola 1 collaboration

Gail P Jarvik 1 collaboration

Henry N Ginsberg 1 collaboration

Lisa Vikström Lilljebjörn 1 collaboration

Eva Csizmadia 1 collaboration

Andreas Hedblom 1 collaboration

Giacomo Canesin 1 collaboration

Alireza Kalbasi 1 collaboration

Mailin Li 1 collaboration

Barbara Wegiel 1 collaboration

Mark J Graham 1 collaboration

Rosanne M Crooke 1 collaboration

Clarence R Manuel 1 collaboration

Rebecca A Haeusler 1 collaboration

Daniel Mar 1 collaboration

Karol Bomsztyk 1 collaboration

John E Hokanson 1 collaboration

Gregory L Kinney 1 collaboration

Panagiotis Fotakis 1 collaboration

David G Thomas 1 collaboration

Marit Westerterp 1 collaboration

Matthew M Molusky 1 collaboration

Elissa Altin 1 collaboration

Sandra Abramowicz 1 collaboration

Nan Wang 1 collaboration

Joseph A Beavo 1 collaboration

Martin Golkowski 1 collaboration

Michael-Claude Beltejar 1 collaboration

Shao-En Ong 1 collaboration

Tatjana Josefs 1 collaboration

Britt Arets 1 collaboration

Lesley-Ann Huggins 1 collaboration

Yunying Hu 1 collaboration

Jianhua Liu 1 collaboration

Rui Guo 1 collaboration

Yinan Hua 1 collaboration

Jun Ren 1 collaboration

Sreejayan Nair 1 collaboration

Shimpi Bedi 1 collaboration

Jamie Morris 1 collaboration

Amy Shah 1 collaboration

Rachel C Hart 1 collaboration

W Gray Jerome 1 collaboration

Stephen G Aller 1 collaboration